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Overview

ID MAG01854
Name HKD3_bin.39
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Actinomycetota
Class Coriobacteriia
Order Anaerosomatales
Family PALSA-660
Genus
Species
Assembly information
Completeness (%) 57.91
Contamination (%) 1.14
GC content (%) 70.0
N50 (bp) 8,982
Genome size (bp) 1,289,311

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1225

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1047983_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004185 246.0
HKD3_k127_1047983_1 protein containing a NRPS condensation (Elongation) domain - - - 0.0000000000000000000000000000000000000000000868 177.0
HKD3_k127_1047983_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000002649 81.0
HKD3_k127_113622_0 Telomere recombination K04656 - - 6.737e-222 719.0
HKD3_k127_113622_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 493.0
HKD3_k127_113622_10 ABC transporter K02006,K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000212 283.0
HKD3_k127_113622_11 response regulator receiver K07705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003822 271.0
HKD3_k127_113622_12 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001938 265.0
HKD3_k127_113622_13 4Fe-4S ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000002433 239.0
HKD3_k127_113622_14 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000004362 202.0
HKD3_k127_113622_15 cobalt ion transport K02007,K16915 - - 0.0000000000000000000000000000000000000000000000000001392 197.0
HKD3_k127_113622_16 Metal-dependent phosphohydrolase, HD region - - - 0.0000000000000000000000000000000000000000000000000005743 208.0
HKD3_k127_113622_17 QueT transporter - - - 0.000000000000000000000000000000000000000000000000001749 188.0
HKD3_k127_113622_18 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000004574 184.0
HKD3_k127_113622_19 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000007037 199.0
HKD3_k127_113622_2 hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 467.0
HKD3_k127_113622_20 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000001316 144.0
HKD3_k127_113622_21 PFAM GGDEF domain containing protein K02488 - 2.7.7.65 0.000000000000000000000000000000006246 146.0
HKD3_k127_113622_22 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000004198 124.0
HKD3_k127_113622_23 Cobalt ABC transporter K02008 - - 0.000000000000000000000000007737 127.0
HKD3_k127_113622_24 PBP superfamily domain K02040 - - 0.000000000000000000000001357 107.0
HKD3_k127_113622_25 membrane transporter protein K07090 - - 0.00000000000000000000001311 110.0
HKD3_k127_113622_26 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000002914 105.0
HKD3_k127_113622_27 hydrogenase assembly chaperone HypC HupF K04653 - - 0.0000000000000000000676 93.0
HKD3_k127_113622_28 SMART Nucleotide binding protein, PINc K07175 - - 0.000000000000000002539 97.0
HKD3_k127_113622_29 Acetyltransferase (GNAT) family K22477 - 2.3.1.1 0.00001397 57.0
HKD3_k127_113622_3 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 450.0
HKD3_k127_113622_30 - - - - 0.00005518 49.0
HKD3_k127_113622_31 Tetratricopeptide repeat - - - 0.0006358 51.0
HKD3_k127_113622_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 447.0
HKD3_k127_113622_5 histidine kinase DNA gyrase B K07704 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 374.0
HKD3_k127_113622_6 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 371.0
HKD3_k127_113622_7 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 356.0
HKD3_k127_113622_8 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 349.0
HKD3_k127_113622_9 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000142 293.0
HKD3_k127_118234_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004371 371.0
HKD3_k127_118234_1 PFAM Aminotransferase class I and II K00639,K00652,K01906 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47,6.2.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 344.0
HKD3_k127_118234_11 integration host factor - - - 0.00007344 45.0
HKD3_k127_118234_2 abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 323.0
HKD3_k127_118234_3 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 293.0
HKD3_k127_118234_4 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002142 261.0
HKD3_k127_118234_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000001224 196.0
HKD3_k127_118234_6 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.00000000000000000000000000000000000000000000000003172 189.0
HKD3_k127_118234_7 protein deglycation K03152,K05520,K12132 - 2.7.11.1,3.5.1.124 0.00000000000000000000000000000000001399 143.0
HKD3_k127_118234_8 Rubrerythrin K19824 - - 0.0000000000000000000000000297 115.0
HKD3_k127_118234_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.7.7.6 0.0000000004439 66.0
HKD3_k127_1218637_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 412.0
HKD3_k127_1218637_1 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000000000000000006312 174.0
HKD3_k127_1218637_2 Essential for sporulation. Interferes with or is a negative regulator of the pathway leading to asymmetric septation K06412 GO:0000003,GO:0008150,GO:0019954,GO:0030436,GO:0032502,GO:0043934 - 0.000000000000000000000008768 104.0
HKD3_k127_1231720_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009212 291.0
HKD3_k127_1231720_1 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000005158 175.0
HKD3_k127_1231720_2 40-residue YVTN family beta-propeller - - - 0.000000000000000000000000000000000000000002184 179.0
HKD3_k127_1231720_3 depolymerase K03932 - - 0.000000000000000000000000000000000002379 158.0
HKD3_k127_1231720_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000001433 141.0
HKD3_k127_1276670_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 453.0
HKD3_k127_1276670_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000003712 188.0
HKD3_k127_1322945_0 Peptidase, U32 family K08303 - - 0.000000000000000000000000000000000001114 149.0
HKD3_k127_1322945_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000003178 79.0
HKD3_k127_1322945_2 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0000002183 61.0
HKD3_k127_1339682_0 TIGRFAM cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 342.0
HKD3_k127_1339682_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000002062 169.0
HKD3_k127_1339682_3 Bacterial regulatory proteins, tetR family - - - 0.000000003532 65.0
HKD3_k127_1339682_4 - - - - 0.00003086 51.0
HKD3_k127_1357126_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000124 251.0
HKD3_k127_1357126_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000006354 110.0
HKD3_k127_1398502_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 7.917e-205 652.0
HKD3_k127_1398502_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 358.0
HKD3_k127_1398502_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007195 332.0
HKD3_k127_1398502_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000001192 259.0
HKD3_k127_1398502_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000006272 226.0
HKD3_k127_1398502_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000004537 72.0
HKD3_k127_1398502_6 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0002845 44.0
HKD3_k127_1439660_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.583e-196 643.0
HKD3_k127_1439660_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007343 544.0
HKD3_k127_1439660_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 472.0
HKD3_k127_1439660_3 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 312.0
HKD3_k127_1439660_4 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000003207 136.0
HKD3_k127_1439660_5 Chorismate mutase type II - - - 0.0000000000000000000005397 98.0
HKD3_k127_1439660_6 Glycosyltransferase Family 4 - - - 0.000008327 50.0
HKD3_k127_1490265_0 Acyl-CoA synthetase (NDP forming) K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 611.0
HKD3_k127_1490265_1 PFAM 2-nitropropane dioxygenase K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 387.0
HKD3_k127_1490265_10 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000001168 80.0
HKD3_k127_1490265_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
HKD3_k127_1490265_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 329.0
HKD3_k127_1490265_4 PFAM DRTGG domain protein K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000133 243.0
HKD3_k127_1490265_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000003238 162.0
HKD3_k127_1490265_6 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000003157 136.0
HKD3_k127_1490265_7 acr, cog1399 K07040 - - 0.0000000000000000000000000005855 120.0
HKD3_k127_1490265_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000001879 113.0
HKD3_k127_1490265_9 Acetyltransferase (GNAT) domain K03830 - - 0.0000000000000003509 87.0
HKD3_k127_1548504_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 418.0
HKD3_k127_1548504_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 403.0
HKD3_k127_1548504_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001413 256.0
HKD3_k127_1548504_3 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient. Cyanobacterial NDH-1 also plays a role in inorganic carbon- concentration K05582 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001917 189.0
HKD3_k127_1548504_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000001541 125.0
HKD3_k127_1548504_5 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.00000000000000000000001107 116.0
HKD3_k127_1548504_6 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.00000000000000002977 87.0
HKD3_k127_1634335_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 579.0
HKD3_k127_1634335_1 MobA-like NTP transferase domain K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 301.0
HKD3_k127_1634335_2 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000007947 241.0
HKD3_k127_1634335_3 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000006691 150.0
HKD3_k127_1673997_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 618.0
HKD3_k127_1673997_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 371.0
HKD3_k127_1673997_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000007143 236.0
HKD3_k127_1673997_3 L,D-transpeptidase catalytic domain - - - 0.0000000000315 73.0
HKD3_k127_1673997_4 - - - - 0.0000002974 61.0
HKD3_k127_1673997_5 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 - 4.1.3.38 0.0000008077 60.0
HKD3_k127_1673997_6 - - - - 0.0000009189 52.0
HKD3_k127_1687370_0 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000001492 248.0
HKD3_k127_1687370_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000009374 232.0
HKD3_k127_1687370_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000002906 238.0
HKD3_k127_1687370_3 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.000000000000000000000000000000000000000003342 168.0
HKD3_k127_1687370_4 - - - - 0.00000000223 68.0
HKD3_k127_1687370_5 PFAM sugar transferase - - - 0.0000007889 50.0
HKD3_k127_1687370_6 Conserved repeat domain - - - 0.000004162 58.0
HKD3_k127_1720899_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 389.0
HKD3_k127_1720899_1 May be required for sporulation K09762 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 369.0
HKD3_k127_1720899_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 317.0
HKD3_k127_1720899_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 301.0
HKD3_k127_1720899_4 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000001602 245.0
HKD3_k127_1720899_5 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000002277 91.0
HKD3_k127_1776116_0 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.000000000000000000000000000000000000000000000004619 185.0
HKD3_k127_1776116_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000077 179.0
HKD3_k127_1776116_2 Acetyltransferase (GNAT) domain - - - 0.000000000235 69.0
HKD3_k127_1907292_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0030312,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0070402,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000009326 243.0
HKD3_k127_1907292_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000003548 243.0
HKD3_k127_1932207_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 621.0
HKD3_k127_1932207_1 Class ii aldolase K01628,K18847 - 2.2.1.8,4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 422.0
HKD3_k127_1932207_2 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 362.0
HKD3_k127_203979_0 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 444.0
HKD3_k127_203979_1 TIGRFAM exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009205 277.0
HKD3_k127_203979_2 O-antigen ligase like membrane protein - - - 0.0000000000000000000001151 115.0
HKD3_k127_216822_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 302.0
HKD3_k127_216822_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006417 243.0
HKD3_k127_216822_10 Transcriptional regulator - - - 0.0002306 49.0
HKD3_k127_216822_2 channel protein, hemolysin III family K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000002036 233.0
HKD3_k127_216822_3 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000001204 240.0
HKD3_k127_216822_4 - - - - 0.00000000000000000000000000000000000000000000000000004774 202.0
HKD3_k127_216822_5 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 K03775 - 5.2.1.8 0.0000000000000000000000000000000000000004811 154.0
HKD3_k127_216822_6 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress - - - 0.000000000000000000000000000000000001526 156.0
HKD3_k127_216822_7 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000488 132.0
HKD3_k127_216822_8 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000003552 96.0
HKD3_k127_216822_9 acetyltransferase - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.00000000007738 74.0
HKD3_k127_2177708_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000008819 141.0
HKD3_k127_2177708_1 branched-chain amino acid - - - 0.000000000001409 69.0
HKD3_k127_218942_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1138.0
HKD3_k127_218942_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 603.0
HKD3_k127_218942_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 471.0
HKD3_k127_218942_3 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001624 287.0
HKD3_k127_218942_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000008712 190.0
HKD3_k127_218942_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000002052 125.0
HKD3_k127_218942_6 TrpR family protein YerC YecD - - - 0.000000000000000000000000005795 113.0
HKD3_k127_218942_7 His Kinase A (phosphoacceptor) domain - - - 0.00000000003924 68.0
HKD3_k127_2313402_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000222 188.0
HKD3_k127_2313402_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000004729 154.0
HKD3_k127_2313402_2 ligase activity - - - 0.0000000000000000000000000000000003885 145.0
HKD3_k127_2313402_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000004673 129.0
HKD3_k127_2313402_4 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000007341 85.0
HKD3_k127_2321075_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 501.0
HKD3_k127_2321075_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000005161 114.0
HKD3_k127_235171_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 490.0
HKD3_k127_235171_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 357.0
HKD3_k127_235171_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000007818 175.0
HKD3_k127_2554912_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.574e-248 786.0
HKD3_k127_2554912_1 1,2-diacylglycerol 3-glucosyltransferase K19002 - 2.4.1.337 0.0000000000000000000000000000000000000000000000000000000000000000000000006084 262.0
HKD3_k127_2554912_2 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.0000000000000000000000000000000000000127 162.0
HKD3_k127_2554912_3 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000004244 119.0
HKD3_k127_2554912_4 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000005629 126.0
HKD3_k127_2554912_5 Rhomboid family K19225 - 3.4.21.105 0.000000001377 66.0
HKD3_k127_2557817_0 Belongs to the transketolase family K00615 - 2.2.1.1 2.521e-196 631.0
HKD3_k127_2557817_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 495.0
HKD3_k127_2557817_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008425 432.0
HKD3_k127_2557817_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 359.0
HKD3_k127_2557817_4 Inositol monophosphatase family K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.00000000000000000000000000000000000000000000000001208 191.0
HKD3_k127_2557817_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000002912 147.0
HKD3_k127_2557817_6 hydrogenase maturation protease K03605 - - 0.000000000000000000000000001461 121.0
HKD3_k127_2557817_7 Cytochrome b/b6/petB K03620 - - 0.000000000000000000000000002969 114.0
HKD3_k127_2578365_0 integral membrane protein MviN K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 372.0
HKD3_k127_2578365_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001719 232.0
HKD3_k127_2613799_0 PFAM Uncharacterised protein family UPF0182 K09118 - - 7.105e-231 745.0
HKD3_k127_2613799_1 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 537.0
HKD3_k127_2613799_10 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000004274 112.0
HKD3_k127_2613799_11 lyase activity - - - 0.000000000000000008217 98.0
HKD3_k127_2613799_12 - - - - 0.0000000000000000249 91.0
HKD3_k127_2613799_13 PFAM PRC-barrel domain - - - 0.0000001488 62.0
HKD3_k127_2613799_15 - - - - 0.000107 49.0
HKD3_k127_2613799_2 Magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 509.0
HKD3_k127_2613799_3 Metal ion transporter, metal ion (Mn2 Fe2 ) transporter (Nramp) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 451.0
HKD3_k127_2613799_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 311.0
HKD3_k127_2613799_5 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000006121 222.0
HKD3_k127_2613799_6 Polysaccharide deacetylase K01181,K22278 - 3.2.1.8,3.5.1.104 0.00000000000000000000000000000000000000000001097 180.0
HKD3_k127_2613799_7 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000001871 157.0
HKD3_k127_2613799_8 Maf-like protein K06287 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000003995 128.0
HKD3_k127_2613799_9 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000006919 117.0
HKD3_k127_2634548_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002061 259.0
HKD3_k127_2634548_1 heat shock protein binding - - - 0.0000000000000000000000000000000001027 147.0
HKD3_k127_2634548_2 PFAM PKD domain containing protein - - - 0.00000000000000000000002076 112.0
HKD3_k127_2713168_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 527.0
HKD3_k127_2713168_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 483.0
HKD3_k127_2713168_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000003052 98.0
HKD3_k127_2713168_3 transcriptional regulator - - - 0.00000000000000000004402 98.0
HKD3_k127_2713168_4 cyclic-guanylate-specific phosphodiesterase activity - - - 0.000002974 61.0
HKD3_k127_2713168_5 cyclic-guanylate-specific phosphodiesterase activity - - - 0.000004756 56.0
HKD3_k127_2713168_6 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K07027 - - 0.000005231 59.0
HKD3_k127_2713168_7 FtsX-like permease family K02004 - - 0.00002767 51.0
HKD3_k127_2713704_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 340.0
HKD3_k127_2713704_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002566 280.0
HKD3_k127_2713704_2 diacylglycerol kinase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000008351 244.0
HKD3_k127_2713704_3 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000001871 128.0
HKD3_k127_2729573_0 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 289.0
HKD3_k127_2729573_1 Immune inhibitor A peptidase M6 K09607 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006482 277.0
HKD3_k127_2729573_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000007481 246.0
HKD3_k127_2745298_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 525.0
HKD3_k127_2745298_1 Hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004734 250.0
HKD3_k127_2745298_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000004166 254.0
HKD3_k127_2745298_3 G5 domain protein - - - 0.00000000000000000000000000000000000004337 157.0
HKD3_k127_2745298_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000001677 147.0
HKD3_k127_2745298_5 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000008253 134.0
HKD3_k127_2745298_6 Biofilm formation stimulator VEG - - - 0.00000000000000000000003578 101.0
HKD3_k127_2745298_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K21681 - 1.1.1.405,2.7.7.40,2.7.7.60 0.000122 50.0
HKD3_k127_2754384_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 589.0
HKD3_k127_2754384_1 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 544.0
HKD3_k127_2754384_10 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 308.0
HKD3_k127_2754384_11 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000006811 170.0
HKD3_k127_2754384_12 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000000000000000000000000001211 163.0
HKD3_k127_2754384_2 penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 471.0
HKD3_k127_2754384_3 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 409.0
HKD3_k127_2754384_4 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005096 404.0
HKD3_k127_2754384_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 378.0
HKD3_k127_2754384_6 Phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 368.0
HKD3_k127_2754384_7 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 330.0
HKD3_k127_2754384_8 PFAM NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 325.0
HKD3_k127_2754384_9 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 324.0
HKD3_k127_2783000_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070,K03789,K14742 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0004596,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006473,GO:0006474,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008080,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008999,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016787,GO:0017189,GO:0018193,GO:0018194,GO:0019538,GO:0030312,GO:0031365,GO:0032991,GO:0034212,GO:0034470,GO:0034641,GO:0034660,GO:0036211,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051604,GO:0070011,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.128,2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 476.0
HKD3_k127_2783000_1 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000002911 221.0
HKD3_k127_2783000_2 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000001146 164.0
HKD3_k127_2783000_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000001242 171.0
HKD3_k127_2783000_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679 - 0.000000000000000000000000000000000003628 139.0
HKD3_k127_2783000_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000001042 136.0
HKD3_k127_2783000_6 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000000000000005767 138.0
HKD3_k127_2783000_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000002448 132.0
HKD3_k127_2790634_0 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 616.0
HKD3_k127_2790634_1 Catalyzes the reversible phosphorolysis of thymidine, deoxyuridine and their analogues to their respective bases and 2-deoxyribose 1-phosphate K00756 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 470.0
HKD3_k127_2790634_2 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006746 276.0
HKD3_k127_2790634_3 PFAM peptidase M50 - - - 0.00005303 47.0
HKD3_k127_2790677_0 type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 517.0
HKD3_k127_2790677_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 339.0
HKD3_k127_2790677_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000001161 93.0
HKD3_k127_2791247_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 288.0
HKD3_k127_2791247_1 RmlD substrate binding domain K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000006681 263.0
HKD3_k127_2791247_2 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000003356 199.0
HKD3_k127_2791247_3 O-acyltransferase activity - - - 0.0000000000000000000000003335 113.0
HKD3_k127_2791247_4 polysaccharide biosynthetic process - - - 0.0000000000000000004501 100.0
HKD3_k127_2791247_5 Acyltransferase - - - 0.000000008256 67.0
HKD3_k127_2856095_0 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 439.0
HKD3_k127_2856095_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 364.0
HKD3_k127_2856095_2 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000634 225.0
HKD3_k127_2856095_3 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000001538 96.0
HKD3_k127_2856095_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000156 56.0
HKD3_k127_2903976_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 598.0
HKD3_k127_2903976_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 557.0
HKD3_k127_2903976_10 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000004582 185.0
HKD3_k127_2903976_11 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000000000000000125 166.0
HKD3_k127_2903976_12 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000001163 133.0
HKD3_k127_2903976_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000001486 114.0
HKD3_k127_2903976_14 - - - - 0.0000000000000000000004423 99.0
HKD3_k127_2903976_15 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000004736 102.0
HKD3_k127_2903976_16 conserved protein (DUF2249) - - - 0.000000001735 64.0
HKD3_k127_2903976_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0001167 48.0
HKD3_k127_2903976_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0007284 46.0
HKD3_k127_2903976_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 526.0
HKD3_k127_2903976_3 ATP dependent DNA ligase domain protein K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 483.0
HKD3_k127_2903976_4 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 419.0
HKD3_k127_2903976_5 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 357.0
HKD3_k127_2903976_6 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 300.0
HKD3_k127_2903976_7 PFAM 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005557 291.0
HKD3_k127_2903976_8 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002548 256.0
HKD3_k127_2903976_9 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000006953 241.0
HKD3_k127_2919199_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 328.0
HKD3_k127_2919199_1 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000003554 238.0
HKD3_k127_2919199_2 aminopeptidase activity K19701,K19702 - 3.4.11.10,3.4.11.24,3.4.11.6 0.0000000000000000000000001702 111.0
HKD3_k127_296442_0 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005531 288.0
HKD3_k127_296442_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003159 262.0
HKD3_k127_296442_2 Acetyl-CoA carboxylase, biotin carboxyl carrier protein K01571 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 256.0
HKD3_k127_296442_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000762 192.0
HKD3_k127_296442_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000002397 124.0
HKD3_k127_3007769_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.134e-265 839.0
HKD3_k127_3007769_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 7.055e-224 709.0
HKD3_k127_3007769_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 446.0
HKD3_k127_3007769_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000008008 235.0
HKD3_k127_3007769_4 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000001029 222.0
HKD3_k127_3007769_5 Belongs to the ribF family K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000005681 218.0
HKD3_k127_3007769_6 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000002171 140.0
HKD3_k127_3007769_7 FMN binding - - - 0.00000000000000000000000000000002521 135.0
HKD3_k127_3007769_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000001903 107.0
HKD3_k127_3007769_9 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.0000000000000000005488 89.0
HKD3_k127_3016914_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 557.0
HKD3_k127_3016914_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 459.0
HKD3_k127_3016914_10 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 296.0
HKD3_k127_3016914_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 295.0
HKD3_k127_3016914_12 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000001365 272.0
HKD3_k127_3016914_13 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003258 265.0
HKD3_k127_3016914_14 MraZ protein, putative antitoxin-like K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000005545 139.0
HKD3_k127_3016914_15 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000000000001296 140.0
HKD3_k127_3016914_16 Cell division protein FtsQ K03589 - - 0.00000000000000000000000001021 122.0
HKD3_k127_3016914_17 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000001759 103.0
HKD3_k127_3016914_2 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 443.0
HKD3_k127_3016914_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 424.0
HKD3_k127_3016914_4 PASTA domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 394.0
HKD3_k127_3016914_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 385.0
HKD3_k127_3016914_6 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 359.0
HKD3_k127_3016914_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 357.0
HKD3_k127_3016914_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 347.0
HKD3_k127_3016914_9 PFAM Branched-chain amino acid transport system permease component K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 293.0
HKD3_k127_3076292_0 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 402.0
HKD3_k127_3076292_1 amidohydrolase K07045 - - 0.000000000000000000000000000000000007062 149.0
HKD3_k127_3076292_2 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000006138 146.0
HKD3_k127_3076292_3 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000313 128.0
HKD3_k127_3076292_4 PFAM Maf family protein K06287 - - 0.0000000005256 64.0
HKD3_k127_3076292_5 Phage-shock protein K03973 - - 0.0000000006881 68.0
HKD3_k127_3076292_6 - - - - 0.00001661 57.0
HKD3_k127_3285701_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 354.0
HKD3_k127_3285701_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000004496 210.0
HKD3_k127_3285701_2 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000008876 179.0
HKD3_k127_3285701_3 ACT domain protein - - - 0.000000000004641 72.0
HKD3_k127_3342531_0 Polysaccharide biosynthesis protein K01784,K08679 - 5.1.3.2,5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 329.0
HKD3_k127_3342531_1 Belongs to the folylpolyglutamate synthase family K11754 GO:0003674,GO:0003824,GO:0004326,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006761,GO:0006807,GO:0008150,GO:0008152,GO:0008841,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046452,GO:0046483,GO:0046900,GO:0046901,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009437 296.0
HKD3_k127_3342531_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0000000009888 59.0
HKD3_k127_3436965_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000001002 245.0
HKD3_k127_3436965_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000001595 100.0
HKD3_k127_3436965_2 TIGRFAM looped-hinge helix DNA binding domain, AbrB family K06284 - - 0.00000000000000005958 85.0
HKD3_k127_3498885_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 4.332e-233 749.0
HKD3_k127_3498885_1 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000004779 131.0
HKD3_k127_3498885_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000008028 96.0
HKD3_k127_3587729_0 DNA topoisomerase K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 511.0
HKD3_k127_3587729_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006823 317.0
HKD3_k127_3587729_2 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 331.0
HKD3_k127_3587729_3 Fumarase C-terminus K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000001055 199.0
HKD3_k127_3587729_4 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000155 206.0
HKD3_k127_3587729_5 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000006554 192.0
HKD3_k127_3587729_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000001163 128.0
HKD3_k127_3683296_0 Endoribonuclease that initiates mRNA decay K18682 - - 3.827e-208 658.0
HKD3_k127_3683296_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.162e-199 640.0
HKD3_k127_3683296_10 pfam ammecr1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 384.0
HKD3_k127_3683296_11 histidine kinase DNA gyrase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 366.0
HKD3_k127_3683296_12 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 359.0
HKD3_k127_3683296_13 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 319.0
HKD3_k127_3683296_14 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009294 292.0
HKD3_k127_3683296_15 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002238 289.0
HKD3_k127_3683296_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001392 283.0
HKD3_k127_3683296_17 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006541 272.0
HKD3_k127_3683296_18 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000002471 257.0
HKD3_k127_3683296_19 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007064 259.0
HKD3_k127_3683296_2 FtsK SpoIIIE family K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 591.0
HKD3_k127_3683296_20 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001758 256.0
HKD3_k127_3683296_21 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000002184 241.0
HKD3_k127_3683296_22 PFAM PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000001562 228.0
HKD3_k127_3683296_23 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000584 224.0
HKD3_k127_3683296_24 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000001196 220.0
HKD3_k127_3683296_25 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000001956 209.0
HKD3_k127_3683296_26 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000001101 198.0
HKD3_k127_3683296_27 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000002616 198.0
HKD3_k127_3683296_28 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000001057 189.0
HKD3_k127_3683296_29 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000002163 148.0
HKD3_k127_3683296_3 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 536.0
HKD3_k127_3683296_30 Stage V sporulation protein S (SpoVS) K06416 - - 0.0000000000000000000000000000000006868 142.0
HKD3_k127_3683296_31 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000373 139.0
HKD3_k127_3683296_32 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000005499 121.0
HKD3_k127_3683296_33 TfoX N-terminal domain - - - 0.00000000000000000000000769 104.0
HKD3_k127_3683296_34 Mechanosensitive ion channel - - - 0.000000000000000001587 90.0
HKD3_k127_3683296_35 Helix-turn-helix domain - - - 0.000000000000000472 89.0
HKD3_k127_3683296_36 Hydrolase, NUDIX family - - - 0.000000000000007316 82.0
HKD3_k127_3683296_37 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000004664 79.0
HKD3_k127_3683296_38 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000008451 77.0
HKD3_k127_3683296_39 membrane K00389 - - 0.0000001462 62.0
HKD3_k127_3683296_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 504.0
HKD3_k127_3683296_40 Ami_3 K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.000009408 54.0
HKD3_k127_3683296_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 505.0
HKD3_k127_3683296_6 permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 492.0
HKD3_k127_3683296_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003357 482.0
HKD3_k127_3683296_8 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 467.0
HKD3_k127_3683296_9 permease K06901 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 445.0
HKD3_k127_3690008_0 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000005719 235.0
HKD3_k127_3690008_1 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000008769 205.0
HKD3_k127_3690008_2 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000001329 181.0
HKD3_k127_3690008_3 Transcriptional regulator - - - 0.00000000000001956 74.0
HKD3_k127_3695300_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 387.0
HKD3_k127_3713193_0 PFAM cation transporter K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 390.0
HKD3_k127_3713193_1 - - - - 0.0000000000000000000005214 111.0
HKD3_k127_3713193_2 Peptidase family M23 - - - 0.000119 49.0
HKD3_k127_3730683_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 602.0
HKD3_k127_3730683_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 490.0
HKD3_k127_3730683_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 490.0
HKD3_k127_3730683_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004677 261.0
HKD3_k127_3730683_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000001766 180.0
HKD3_k127_3730683_5 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.00000000000000000000259 97.0
HKD3_k127_3738578_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 404.0
HKD3_k127_3738578_1 PFAM Response regulator receiver domain K07658 - - 0.0000000000000000000000000000002385 128.0
HKD3_k127_3738578_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000006277 127.0
HKD3_k127_3738578_3 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000005076 119.0
HKD3_k127_3760967_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 460.0
HKD3_k127_3760967_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 305.0
HKD3_k127_3760967_2 Glycosyl transferase family 4 K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016043,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0034645,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0045229,GO:0046872,GO:0046914,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:1901576 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000116 285.0
HKD3_k127_3760967_3 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000001962 224.0
HKD3_k127_3760967_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000002625 203.0
HKD3_k127_3760967_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation - - - 0.000000000000000008304 86.0
HKD3_k127_3760967_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000001785 68.0
HKD3_k127_376882_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.527e-275 858.0
HKD3_k127_376882_1 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000001716 207.0
HKD3_k127_376882_2 transcriptional regulator K07667 - - 0.00000000000000000000000000000000000000000000000001485 188.0
HKD3_k127_376882_3 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.000000000000000000000000000000000003062 154.0
HKD3_k127_376882_4 Double zinc ribbon - - - 0.00000000000000000000000000000000003412 139.0
HKD3_k127_3781012_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1022.0
HKD3_k127_3781012_1 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 524.0
HKD3_k127_3781012_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 483.0
HKD3_k127_3781012_3 Phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 466.0
HKD3_k127_3781012_4 Peptidase S24-like K13280 - 3.4.21.89 0.000002085 59.0
HKD3_k127_3793618_0 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 618.0
HKD3_k127_3793618_1 DHHA2 K15986 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 410.0
HKD3_k127_3793618_2 Response regulator receiver K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000005239 234.0
HKD3_k127_3793618_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000001268 233.0
HKD3_k127_3793618_4 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000005928 228.0
HKD3_k127_3793618_5 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000004024 232.0
HKD3_k127_3793618_6 LssY C-terminus - - - 0.00000000000000000000000000000007304 143.0
HKD3_k127_3793618_7 PFAM phosphoesterase PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000003214 109.0
HKD3_k127_3797168_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 569.0
HKD3_k127_3797168_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 492.0
HKD3_k127_3797168_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000227 237.0
HKD3_k127_3797168_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000001289 196.0
HKD3_k127_3797168_4 NAD-dependent epimerase dehydratase - - - 0.0000000000008154 76.0
HKD3_k127_3802306_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 553.0
HKD3_k127_3802306_1 glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 443.0
HKD3_k127_3802306_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 403.0
HKD3_k127_3802306_3 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 314.0
HKD3_k127_3802306_4 Peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000004639 169.0
HKD3_k127_3802306_5 NLP P60 protein K21471 - - 0.0000000000000000000000000000000000000002298 166.0
HKD3_k127_3802306_6 chemotaxis K03406 - - 0.00000000000000000000000000000000000001975 158.0
HKD3_k127_3802306_7 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000004043 120.0
HKD3_k127_3802306_8 VanZ like family - - - 0.000000000000000001256 92.0
HKD3_k127_3805064_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 488.0
HKD3_k127_3805064_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 462.0
HKD3_k127_3805064_2 2-nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 353.0
HKD3_k127_3805064_3 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 288.0
HKD3_k127_3805064_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000005833 184.0
HKD3_k127_3805064_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000003369 130.0
HKD3_k127_3805064_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000009088 114.0
HKD3_k127_3807056_0 polyphosphate kinase K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 408.0
HKD3_k127_3807056_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.000000000000000000000000000000000000000000000000005195 185.0
HKD3_k127_3807056_2 metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000001784 186.0
HKD3_k127_3807056_3 - - - - 0.0000000000000003545 87.0
HKD3_k127_3807056_4 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000003899 76.0
HKD3_k127_3871686_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 407.0
HKD3_k127_3871686_1 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 351.0
HKD3_k127_3871686_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 338.0
HKD3_k127_3871686_3 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000001597 216.0
HKD3_k127_3871686_4 GGDEF domain - - - 0.00000000000000000000000000000001291 141.0
HKD3_k127_3871686_5 Protein of unknown function (DUF2469) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000614 83.0
HKD3_k127_3899273_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 442.0
HKD3_k127_3899273_1 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 314.0
HKD3_k127_3899273_2 TipAS antibiotic-recognition domain K21744 - - 0.0000000000000000000000000000000000000000000000000002234 189.0
HKD3_k127_3910974_0 - - - - 0.0000000000000000000000000000006208 129.0
HKD3_k127_3910974_1 FtsX-like permease family K02004 - - 0.000000000000000163 90.0
HKD3_k127_3910974_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000001721 81.0
HKD3_k127_3916212_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 387.0
HKD3_k127_3916212_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003298 290.0
HKD3_k127_3916212_2 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000002883 228.0
HKD3_k127_3916212_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000003443 140.0
HKD3_k127_3916212_4 PFAM Fimbrial assembly family protein K02663 - - 0.000002287 57.0
HKD3_k127_3916212_5 PFAM Pilus assembly protein PilO K02664 - - 0.000184 51.0
HKD3_k127_3983850_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 304.0
HKD3_k127_3983850_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000003906 147.0
HKD3_k127_4031244_0 biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 480.0
HKD3_k127_4031244_1 PFAM ABC transporter K01990,K02193,K09697 - 3.6.3.41,3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 306.0
HKD3_k127_4031244_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000002517 66.0
HKD3_k127_4031244_11 Tetrapyrrole (Corrin/Porphyrin) Methylases K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.0000004463 52.0
HKD3_k127_4031244_2 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 303.0
HKD3_k127_4031244_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000004585 266.0
HKD3_k127_4031244_4 heme exporter protein CcmB K02194 - - 0.00000000000000000000000000000000000000000000000000000000000001346 223.0
HKD3_k127_4031244_5 Transcriptional regulatory protein, C terminal K07668,K07775 - - 0.00000000000000000000000000000000000000000000000000000000000002662 225.0
HKD3_k127_4031244_6 Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000009831 211.0
HKD3_k127_4031244_7 histidine kinase DNA gyrase B - - - 0.000000000000000000000000000000000000002493 162.0
HKD3_k127_4031244_8 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000001234 149.0
HKD3_k127_4031244_9 Cytochrome c assembly protein - - - 0.0000000005537 70.0
HKD3_k127_4054814_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 417.0
HKD3_k127_4054814_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007352 274.0
HKD3_k127_4054814_2 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000001173 188.0
HKD3_k127_4054814_3 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000004047 125.0
HKD3_k127_418578_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 463.0
HKD3_k127_418578_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 396.0
HKD3_k127_418578_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 327.0
HKD3_k127_418578_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000009513 235.0
HKD3_k127_418578_4 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000001199 181.0
HKD3_k127_418578_5 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000001641 157.0
HKD3_k127_418578_6 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000003888 144.0
HKD3_k127_4196698_0 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 409.0
HKD3_k127_4196698_1 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000004849 202.0
HKD3_k127_4196698_2 IrrE N-terminal-like domain - - - 0.00000134 57.0
HKD3_k127_4196698_3 - - - - 0.0000171 58.0
HKD3_k127_4311532_0 Putative glucoamylase K13688 - - 0.0 1356.0
HKD3_k127_4311532_1 PFAM Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000001591 162.0
HKD3_k127_4311532_2 Bifunctional nuclease K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000183 146.0
HKD3_k127_4311532_3 PFAM NADPH-dependent FMN reductase - - - 0.00000000000003939 78.0
HKD3_k127_4369841_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1496.0
HKD3_k127_4369841_1 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 461.0
HKD3_k127_4369841_2 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 403.0
HKD3_k127_4369841_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000105 232.0
HKD3_k127_4369841_4 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000001276 232.0
HKD3_k127_4369841_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000005558 216.0
HKD3_k127_4369841_6 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000001161 187.0
HKD3_k127_4369841_7 integration host factor - - - 0.00000000000000000000000000005965 124.0
HKD3_k127_4369841_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000003887 116.0
HKD3_k127_4392784_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1231.0
HKD3_k127_4392784_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 399.0
HKD3_k127_4392784_2 Transcriptional modulator of MazE toxin, MazF K07171,K18841 GO:0001558,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0022607,GO:0030308,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0040008,GO:0042802,GO:0042803,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044877,GO:0045926,GO:0046483,GO:0046700,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051259,GO:0051291,GO:0060255,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000002724 133.0
HKD3_k127_4401546_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 2.103e-227 716.0
HKD3_k127_4401546_1 Glycosyl transferase, family 2 - - - 0.000000000006141 74.0
HKD3_k127_4428789_0 GTP-binding protein TypA K06207 - - 1.479e-200 640.0
HKD3_k127_4428789_1 PFAM Rubrerythrin - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007353 278.0
HKD3_k127_4428789_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007001 248.0
HKD3_k127_447084_0 PFAM Band 7 protein - - - 3.367e-272 856.0
HKD3_k127_447084_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 565.0
HKD3_k127_447084_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.0000000000000000000000000000000000000000000000007853 184.0
HKD3_k127_447084_11 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000008072 171.0
HKD3_k127_447084_12 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000005795 155.0
HKD3_k127_447084_13 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000005318 166.0
HKD3_k127_447084_14 Protein of unknown function (DUF1648) - - - 0.00000000000000000000000000000000000009899 154.0
HKD3_k127_447084_15 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000001603 138.0
HKD3_k127_447084_16 ArsR family transcriptional regulator - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000001431 116.0
HKD3_k127_447084_17 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000001517 94.0
HKD3_k127_447084_18 Zn-dependent protease with chaperone function K03799 - - 0.00000000002282 76.0
HKD3_k127_447084_19 - - - - 0.0000001392 59.0
HKD3_k127_447084_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 495.0
HKD3_k127_447084_20 cheY-homologous receiver domain K03413 - - 0.000007411 49.0
HKD3_k127_447084_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007486 475.0
HKD3_k127_447084_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 359.0
HKD3_k127_447084_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 351.0
HKD3_k127_447084_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 357.0
HKD3_k127_447084_7 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000001812 258.0
HKD3_k127_447084_8 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000007043 238.0
HKD3_k127_447084_9 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000111 236.0
HKD3_k127_4506917_0 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 434.0
HKD3_k127_464451_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.019e-230 730.0
HKD3_k127_464451_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000004488 171.0
HKD3_k127_464451_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000003269 165.0
HKD3_k127_464451_3 response regulator - - - 0.0000000000000000002904 102.0
HKD3_k127_4749105_0 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001804 277.0
HKD3_k127_4749105_1 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000004245 214.0
HKD3_k127_4749105_2 Phosphoribosyl transferase domain - - - 0.0000000000000000001942 92.0
HKD3_k127_4749105_3 Redoxin - - - 0.00000000003892 69.0
HKD3_k127_4877487_0 transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 381.0
HKD3_k127_4877487_1 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 333.0
HKD3_k127_4877487_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 310.0
HKD3_k127_4877487_3 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000009522 185.0
HKD3_k127_4877487_4 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000007328 148.0
HKD3_k127_4877487_5 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000001249 146.0
HKD3_k127_4877487_6 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000001119 97.0
HKD3_k127_4877487_7 methyltransferase - - - 0.0000003774 59.0
HKD3_k127_4923935_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 349.0
HKD3_k127_4923935_1 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005423 278.0
HKD3_k127_4923935_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190,K05350 - 3.2.1.21,3.2.1.23 0.000000002495 68.0
HKD3_k127_4925130_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 8.188e-216 687.0
HKD3_k127_4925130_1 NeuB family K01654 - 2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 574.0
HKD3_k127_4925130_2 PFAM Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 401.0
HKD3_k127_4925130_3 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 297.0
HKD3_k127_4925130_4 ADP-glyceromanno-heptose 6-epimerase activity K01710,K01784 - 4.2.1.46,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001073 293.0
HKD3_k127_4925130_5 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005877 269.0
HKD3_k127_4978795_0 phosphate starvation-inducible protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 421.0
HKD3_k127_4978795_1 7TM receptor with intracellular HD hydrolase K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003715 261.0
HKD3_k127_4978795_2 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.000000000000000000000000000000000000000000000006369 191.0
HKD3_k127_4978795_3 CBS domain - - - 0.00000000000000000000000000000000000000000000005213 188.0
HKD3_k127_4978795_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000001453 126.0
HKD3_k127_4978795_5 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.0000000000000000000000000005474 118.0
HKD3_k127_4998081_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1110.0
HKD3_k127_4998081_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 341.0
HKD3_k127_4998081_10 belongs to the nudix hydrolase family - - - 0.000148 51.0
HKD3_k127_4998081_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000258 253.0
HKD3_k127_4998081_3 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000004732 213.0
HKD3_k127_4998081_4 peptidyl-prolyl isomerase K07533 - 5.2.1.8 0.000000000000000000000000000000001012 143.0
HKD3_k127_4998081_5 deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000008172 138.0
HKD3_k127_4998081_6 Redoxin K03564 - 1.11.1.15 0.00000000000000000001024 94.0
HKD3_k127_4998081_7 PFAM blue (type 1) copper domain protein - - - 0.0000000000000003108 87.0
HKD3_k127_4998081_8 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.00000007512 55.0
HKD3_k127_4998081_9 Phosphoribosyl-ATP pyrophosphohydrolase K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.000005446 59.0
HKD3_k127_5036761_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008841 243.0
HKD3_k127_5036761_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000009795 210.0
HKD3_k127_5072011_0 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000002946 228.0
HKD3_k127_5072011_1 potassium uptake protein TrkH K03498 - - 0.000000000000000000000000000000000000000000000000000000008476 205.0
HKD3_k127_5072011_10 Protein of unknown function (DUF1461) - - - 0.00000000000004578 84.0
HKD3_k127_5072011_11 PFAM Peptidase family M28 - - - 0.0000000000002845 83.0
HKD3_k127_5072011_12 WYL domain K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000001802 81.0
HKD3_k127_5072011_13 - - - - 0.000000005266 66.0
HKD3_k127_5072011_2 TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000001786 190.0
HKD3_k127_5072011_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000003815 190.0
HKD3_k127_5072011_4 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000001195 160.0
HKD3_k127_5072011_5 domain, Protein - - - 0.00000000000000000000000000000003383 145.0
HKD3_k127_5072011_7 cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000000000000001713 116.0
HKD3_k127_5072011_8 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000009845 118.0
HKD3_k127_5072011_9 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.00000000000000005249 82.0
HKD3_k127_5072193_0 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 378.0
HKD3_k127_5072193_1 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 355.0
HKD3_k127_5072193_2 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 319.0
HKD3_k127_5072193_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001731 290.0
HKD3_k127_5072193_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000001926 231.0
HKD3_k127_5072193_5 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000001207 74.0
HKD3_k127_5074100_0 Thiamine pyrophosphokinase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 431.0
HKD3_k127_5074100_1 May be involved in recombinational repair of damaged DNA K03631,K13582 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0030312,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000005596 198.0
HKD3_k127_5074100_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000001795 154.0
HKD3_k127_5074100_3 Copper transport outer membrane protein, MctB - - - 0.00000000444 67.0
HKD3_k127_5082159_0 metallopeptidase activity K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 515.0
HKD3_k127_5082159_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009975 275.0
HKD3_k127_5082159_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000001248 165.0
HKD3_k127_5082159_3 NLP P60 protein K21471 - - 0.00000000000000000000000000000000000000000469 173.0
HKD3_k127_5082159_4 Histidine kinase - - - 0.0003578 51.0
HKD3_k127_5208564_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.88e-250 782.0
HKD3_k127_5208564_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007795 508.0
HKD3_k127_5208564_2 Peptidase dimerisation domain K01258 - 3.4.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 341.0
HKD3_k127_5208564_3 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 331.0
HKD3_k127_5208564_4 Basic membrane lipoprotein K07335 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003613 286.0
HKD3_k127_5208564_5 Protein of unknown function (DUF3866) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002848 283.0
HKD3_k127_5208564_6 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000005279 182.0
HKD3_k127_5208564_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan - - - 0.0000000000000000000000000002537 130.0
HKD3_k127_5208564_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000001658 125.0
HKD3_k127_523946_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 334.0
HKD3_k127_523946_1 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000001992 66.0
HKD3_k127_523946_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000004377 55.0
HKD3_k127_5266081_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K13019 - 5.1.3.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 421.0
HKD3_k127_5266081_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 410.0
HKD3_k127_5266081_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 334.0
HKD3_k127_5266081_3 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
HKD3_k127_5266081_4 Hexapeptide repeat of succinyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001518 243.0
HKD3_k127_5266081_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000004201 83.0
HKD3_k127_5323302_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.484e-311 976.0
HKD3_k127_5323302_1 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 576.0
HKD3_k127_5323302_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000000000003303 144.0
HKD3_k127_5323302_11 - K04757 - 2.7.11.1 0.0000000000000000001495 93.0
HKD3_k127_5323302_12 - - - - 0.000000000002276 76.0
HKD3_k127_5323302_13 Bacterial protein of unknown function (DUF948) - - - 0.0009868 47.0
HKD3_k127_5323302_2 PFAM AAA ATPase central domain protein K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 536.0
HKD3_k127_5323302_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004683 475.0
HKD3_k127_5323302_4 RNA polymerase sigma-70 factor, sigma-B F G subfamily K03090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 312.0
HKD3_k127_5323302_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001515 257.0
HKD3_k127_5323302_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000341 232.0
HKD3_k127_5323302_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000005733 209.0
HKD3_k127_5323302_8 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000189 202.0
HKD3_k127_5323302_9 HAD superfamily (Subfamily IIIA) phosphatase, TIGR01668 K07015 - - 0.000000000000000000000000000000000000006417 160.0
HKD3_k127_5323740_0 CDP-glucose 4,6-dehydratase K01709 - 4.2.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 394.0
HKD3_k127_5323740_1 Belongs to the DegT DnrJ EryC1 family K12452 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 396.0
HKD3_k127_5323740_2 Nucleotidyl transferase K00978 - 2.7.7.33 0.000000000000000000000000000000000000000000000000000000002357 202.0
HKD3_k127_5368944_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 512.0
HKD3_k127_5368944_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000002026 269.0
HKD3_k127_5368944_2 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000004106 202.0
HKD3_k127_5368944_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000005392 113.0
HKD3_k127_5385645_0 Cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 478.0
HKD3_k127_5385645_1 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 458.0
HKD3_k127_5385645_10 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000007751 190.0
HKD3_k127_5385645_11 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000003073 189.0
HKD3_k127_5385645_12 electron transport chain K02560,K03613,K10773 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 2.3.1.243,4.2.99.18 0.000000000000000000000000000000000000000000000000004169 188.0
HKD3_k127_5385645_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000001447 190.0
HKD3_k127_5385645_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000001071 149.0
HKD3_k127_5385645_15 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000286 130.0
HKD3_k127_5385645_16 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000001452 90.0
HKD3_k127_5385645_17 Psort location CytoplasmicMembrane, score K00805 - 2.5.1.30 0.0000000000008847 78.0
HKD3_k127_5385645_18 NusG domain II - - - 0.000004303 59.0
HKD3_k127_5385645_2 Nickel-dependent hydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 429.0
HKD3_k127_5385645_3 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 415.0
HKD3_k127_5385645_4 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 366.0
HKD3_k127_5385645_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 345.0
HKD3_k127_5385645_6 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000252 257.0
HKD3_k127_5385645_7 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000002549 252.0
HKD3_k127_5385645_8 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000002178 239.0
HKD3_k127_5385645_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000002171 201.0
HKD3_k127_538977_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009949 481.0
HKD3_k127_538977_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 448.0
HKD3_k127_538977_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 342.0
HKD3_k127_538977_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000000000000671 239.0
HKD3_k127_538977_4 sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000001237 154.0
HKD3_k127_538977_5 SMART Metal-dependent phosphohydrolase, HD region K00969 - 2.7.7.18 0.000000000000000000000000000000000003386 145.0
HKD3_k127_538977_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000001124 136.0
HKD3_k127_538977_7 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000005786 99.0
HKD3_k127_538977_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000001178 76.0
HKD3_k127_538977_9 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.0001016 55.0
HKD3_k127_5578769_0 Sigma-70, region 4 K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004164 324.0
HKD3_k127_5578769_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 320.0
HKD3_k127_5578769_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 301.0
HKD3_k127_5578769_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002481 282.0
HKD3_k127_5578769_4 tyrosine recombinase XerC K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000001798 209.0
HKD3_k127_5578769_5 PFAM response regulator receiver K07657 - - 0.00000000000000000002011 100.0
HKD3_k127_5649928_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K16881 - 2.7.7.13,5.4.2.8 6.557e-232 744.0
HKD3_k127_5649928_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 574.0
HKD3_k127_5649928_10 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000001349 209.0
HKD3_k127_5649928_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000001822 175.0
HKD3_k127_5649928_12 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000000000000000000000000002328 169.0
HKD3_k127_5649928_13 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.00000000000000000000000000000000000004 147.0
HKD3_k127_5649928_14 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000001481 142.0
HKD3_k127_5649928_15 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000006842 151.0
HKD3_k127_5649928_16 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000001585 138.0
HKD3_k127_5649928_17 Forkhead associated domain - - - 0.000000000000000000000000001837 119.0
HKD3_k127_5649928_18 peptidoglycan binding K03642 - - 0.000000000000000000000003274 105.0
HKD3_k127_5649928_19 - - - - 0.000000000001218 74.0
HKD3_k127_5649928_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 557.0
HKD3_k127_5649928_20 Prepilin-type cleavage methylation N-terminal domain protein K02456 - - 0.0000000271 60.0
HKD3_k127_5649928_21 Sigma factor PP2C-like phosphatases - - - 0.000009705 49.0
HKD3_k127_5649928_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 439.0
HKD3_k127_5649928_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 319.0
HKD3_k127_5649928_5 TrkA-N domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002446 276.0
HKD3_k127_5649928_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000001983 246.0
HKD3_k127_5649928_7 VanW like protein - - - 0.0000000000000000000000000000000000000000000000000000000000002026 235.0
HKD3_k127_5649928_8 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000006465 204.0
HKD3_k127_5649928_9 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.00000000000000000000000000000000000000000000000000000007244 201.0
HKD3_k127_57104_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.733e-227 721.0
HKD3_k127_57104_1 Ribosomal RNA large subunit methyltransferase J K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000003375 264.0
HKD3_k127_57104_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000008839 232.0
HKD3_k127_57104_3 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000119 167.0
HKD3_k127_57104_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006797,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000006759 167.0
HKD3_k127_57104_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000226 141.0
HKD3_k127_57104_6 Asp23 family, cell envelope-related function - - - 0.00000000000000000002847 94.0
HKD3_k127_57104_7 Exonuclease VII small subunit - - - 0.0003381 48.0
HKD3_k127_5799826_0 response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 342.0
HKD3_k127_5799826_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 352.0
HKD3_k127_5799826_2 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 321.0
HKD3_k127_5799826_3 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000001608 238.0
HKD3_k127_5799826_4 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000001711 134.0
HKD3_k127_5799826_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000003564 127.0
HKD3_k127_582036_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 411.0
HKD3_k127_582036_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 381.0
HKD3_k127_582036_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 292.0
HKD3_k127_582036_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004854 271.0
HKD3_k127_582036_4 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000005562 226.0
HKD3_k127_582036_5 RIP metalloprotease RseP K11749 - - 0.0000000000000000000000000000000000000000000000000000001264 214.0
HKD3_k127_582036_6 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000009029 192.0
HKD3_k127_582036_7 PFAM Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000006631 139.0
HKD3_k127_5969627_0 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 410.0
HKD3_k127_5969627_1 branched-chain amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005368 288.0
HKD3_k127_5969627_11 Transcriptional regulator - - - 0.000000000188 72.0
HKD3_k127_5969627_12 Transcriptional regulator K13572,K13573 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000201 56.0
HKD3_k127_5969627_2 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001809 308.0
HKD3_k127_5969627_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000168 251.0
HKD3_k127_5969627_4 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000007686 251.0
HKD3_k127_5969627_5 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000001983 188.0
HKD3_k127_5969627_6 N-acetylglucosaminylinositol deacetylase activity - - - 0.00000000000000000000000000006738 126.0
HKD3_k127_5969627_7 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000523 107.0
HKD3_k127_5969627_8 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000000000000142 94.0
HKD3_k127_5969627_9 PFAM glutaredoxin - - - 0.00000000000000003463 89.0
HKD3_k127_6112690_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 300.0
HKD3_k127_6112690_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003484 255.0
HKD3_k127_6112690_2 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000005771 258.0
HKD3_k127_6112690_3 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000003782 177.0
HKD3_k127_6112690_4 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231,K02232 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568 2.7.1.156,2.7.7.62,6.3.5.10 0.0000000000000000000003476 111.0
HKD3_k127_6145879_0 Cation transporting ATPase, C-terminus K01531 - 3.6.3.2 6.348e-293 933.0
HKD3_k127_6145879_1 OST-HTH/LOTUS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 296.0
HKD3_k127_6145879_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K09565 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000001074 167.0
HKD3_k127_6145879_3 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000001015 160.0
HKD3_k127_6145879_4 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000001294 91.0
HKD3_k127_6145879_5 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.00000000000005592 73.0
HKD3_k127_6145879_6 heat shock protein binding K05516 - - 0.0000000000008097 73.0
HKD3_k127_6164903_0 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000003687 209.0
HKD3_k127_6164903_1 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000001745 139.0
HKD3_k127_6164903_2 transcriptional regulator K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000000000000000003849 93.0
HKD3_k127_6170656_0 pilus assembly protein ATPase CpaF K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 544.0
HKD3_k127_6170656_1 Evidence 2b Function of strongly homologous gene K02282 - - 0.00000000000000000000000000000000000000000000000000000005764 213.0
HKD3_k127_6170656_2 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000001115 112.0
HKD3_k127_6170656_3 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.00000000000000002548 91.0
HKD3_k127_6195709_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 326.0
HKD3_k127_6195709_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006051 318.0
HKD3_k127_6195709_10 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000001317 165.0
HKD3_k127_6195709_11 Protein of unknown function (DUF2089) - - - 0.0000000000000000000000000000000000013 142.0
HKD3_k127_6195709_12 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000001485 138.0
HKD3_k127_6195709_13 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.0000000000000000000000000000006829 137.0
HKD3_k127_6195709_14 - - - - 0.0000000000000000000001035 103.0
HKD3_k127_6195709_15 - - - - 0.000000000000000000009653 102.0
HKD3_k127_6195709_16 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.00000000000000000001299 99.0
HKD3_k127_6195709_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000001183 77.0
HKD3_k127_6195709_18 - - - - 0.0000000179 59.0
HKD3_k127_6195709_19 deoxyhypusine monooxygenase activity K01256,K01387 - 3.4.11.2,3.4.24.3 0.0002433 53.0
HKD3_k127_6195709_2 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 298.0
HKD3_k127_6195709_20 - - - - 0.0009972 48.0
HKD3_k127_6195709_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009488 240.0
HKD3_k127_6195709_4 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000001227 228.0
HKD3_k127_6195709_5 zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
HKD3_k127_6195709_6 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000001334 219.0
HKD3_k127_6195709_7 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000001841 210.0
HKD3_k127_6195709_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000002363 173.0
HKD3_k127_6195709_9 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000003986 179.0
HKD3_k127_6196979_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000531 183.0
HKD3_k127_6196979_1 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000001618 175.0
HKD3_k127_6196979_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000004475 69.0
HKD3_k127_6225723_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 583.0
HKD3_k127_6225723_1 UDP-N-acetylglucosamine 2-epimerase K08068,K18429 - 3.2.1.183,3.2.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 548.0
HKD3_k127_6225723_10 PFAM Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000001189 218.0
HKD3_k127_6225723_11 PFAM Polysaccharide biosynthesis protein - - - 0.00000000000000005781 93.0
HKD3_k127_6225723_13 PFAM mannose-6-phosphate isomerase, type II K16011 - 2.7.7.13,5.3.1.8 0.0000000004921 60.0
HKD3_k127_6225723_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 461.0
HKD3_k127_6225723_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 361.0
HKD3_k127_6225723_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 355.0
HKD3_k127_6225723_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 351.0
HKD3_k127_6225723_6 NeuB family K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 342.0
HKD3_k127_6225723_7 Cytidylyltransferase K00983,K18431 - 2.7.7.43,2.7.7.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005286 282.0
HKD3_k127_6225723_8 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000003227 241.0
HKD3_k127_6261012_0 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 442.0
HKD3_k127_6261012_1 PFAM LOR SDH bifunctional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 442.0
HKD3_k127_6261012_2 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000001748 80.0
HKD3_k127_628244_0 Glycosyltransferase 36 associated - - - 0.0 1206.0
HKD3_k127_628244_1 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 587.0
HKD3_k127_628244_2 amino acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 293.0
HKD3_k127_628244_3 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000002772 137.0
HKD3_k127_628244_4 COG0607 Rhodanese-related sulfurtransferase K03972 - - 0.00000000000000131 83.0
HKD3_k127_628244_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K06196 - - 0.000000008316 59.0
HKD3_k127_628265_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008066 286.0
HKD3_k127_628265_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000002941 179.0
HKD3_k127_628265_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000002692 169.0
HKD3_k127_628265_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000001626 172.0
HKD3_k127_628265_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000004849 160.0
HKD3_k127_628265_5 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000007888 96.0
HKD3_k127_628265_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000008105 95.0
HKD3_k127_628265_7 Belongs to the UPF0109 family K06960 - - 0.00000009445 53.0
HKD3_k127_6313915_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 484.0
HKD3_k127_6313915_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006441 245.0
HKD3_k127_6313915_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000263 179.0
HKD3_k127_6341234_0 - - - - 0.0000000000008401 73.0
HKD3_k127_6405182_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 7.604e-300 937.0
HKD3_k127_6405182_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004662 304.0
HKD3_k127_6405182_2 Prolipoprotein diacylglyceryl transferase K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 291.0
HKD3_k127_6405182_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002866 243.0
HKD3_k127_6405182_4 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000009043 207.0
HKD3_k127_6405182_5 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000002953 159.0
HKD3_k127_6405182_6 PFAM AzlC family protein - - - 0.00000000000000000000000000000000000005893 153.0
HKD3_k127_6405182_7 - - - - 0.0000000000000000002349 91.0
HKD3_k127_6405182_8 Protein of unknown function (DUF3048) C-terminal domain - - - 0.000000000000000001759 93.0
HKD3_k127_6405182_9 branched-chain amino acid - - - 0.00000000000003721 83.0
HKD3_k127_6595139_0 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000008972 236.0
HKD3_k127_6595139_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000001873 121.0
HKD3_k127_6595139_2 PFAM SpoVT AbrB K07172 - - 0.0000000000000000000008156 97.0
HKD3_k127_6595139_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000002418 73.0
HKD3_k127_6722793_0 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000000000000001737 187.0
HKD3_k127_6722793_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000001239 180.0
HKD3_k127_6722793_10 Heavy-metal-associated domain K01533,K07213,K07496,K17686 - 3.6.3.4,3.6.3.54 0.00000009437 57.0
HKD3_k127_6722793_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000002074 173.0
HKD3_k127_6722793_3 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000000000000002496 173.0
HKD3_k127_6722793_4 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000001672 134.0
HKD3_k127_6722793_5 PFAM Nitroreductase - - - 0.00000000000000000000000004825 115.0
HKD3_k127_6722793_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000003478 103.0
HKD3_k127_6722793_7 mannose-ethanolamine phosphotransferase activity K05288 - - 0.0000000000000002379 93.0
HKD3_k127_6722793_8 UDP-N-acetylglucosamine LPS N-acetylglucosamine transferase K03429 GO:0003674,GO:0003824,GO:0008194,GO:0016740,GO:0016757,GO:0016758,GO:0035251,GO:0046527,GO:0047228 2.4.1.315 0.00000000001896 76.0
HKD3_k127_6722793_9 - - - - 0.0000000002473 66.0
HKD3_k127_6813311_0 TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 456.0
HKD3_k127_6813311_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 399.0
HKD3_k127_6813311_2 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000006403 96.0
HKD3_k127_6813311_3 Catalyzes the coenzyme A dependent formation of succinyl-CoA from 2-oxoglutarate and ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.0000000003387 64.0
HKD3_k127_6813311_4 Major facilitator Superfamily - - - 0.0000002234 52.0
HKD3_k127_6821390_0 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000001414 192.0
HKD3_k127_6821390_1 SNARE associated Golgi protein K03975 - - 0.00000000000000000000001193 113.0
HKD3_k127_6837645_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000002645 271.0
HKD3_k127_6837645_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000002363 244.0
HKD3_k127_6837645_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000005121 64.0
HKD3_k127_6863880_0 DAK2 domain fusion protein YloV K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 502.0
HKD3_k127_6863880_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000001564 203.0
HKD3_k127_6863880_2 Proton-coupled thiamine transporter YuaJ K16789 - - 0.00000000000000000000000000000000000000004671 160.0
HKD3_k127_6863880_3 Asp23 family, cell envelope-related function - - - 0.00000000000000000000000000000002548 132.0
HKD3_k127_6863880_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000004937 101.0
HKD3_k127_6863880_5 PFAM Thiamin pyrophosphokinase catalytic K00949 - 2.7.6.2 0.00000000000001498 84.0
HKD3_k127_6863880_6 TIGRFAM degV family protein - - - 0.00000918 54.0
HKD3_k127_6863880_7 cluster protein-associated redox disulfide domain protein - - - 0.0001376 51.0
HKD3_k127_6915572_0 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003286 254.0
HKD3_k127_6915572_1 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000945 184.0
HKD3_k127_707673_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 354.0
HKD3_k127_707673_1 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit, TIM barrel K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 328.0
HKD3_k127_707673_2 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002908 259.0
HKD3_k127_707673_3 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000008844 204.0
HKD3_k127_707673_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000002891 180.0
HKD3_k127_707673_5 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000004305 161.0
HKD3_k127_707673_6 4Fe-4S binding domain - - - 0.000000000000000000000000002855 124.0
HKD3_k127_707673_7 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000002577 111.0
HKD3_k127_7251427_0 ABC transporter, transmembrane region K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 511.0
HKD3_k127_7251427_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 415.0
HKD3_k127_7251427_2 Immune inhibitor A peptidase M6 K09607 - - 0.0000000000000000000000000000000000000000000000000000000000000000002854 237.0
HKD3_k127_7251427_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000009792 175.0
HKD3_k127_7251427_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000002178 147.0
HKD3_k127_7269146_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 574.0
HKD3_k127_7269146_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 489.0
HKD3_k127_7269146_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009644 277.0
HKD3_k127_7269146_11 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000005318 263.0
HKD3_k127_7269146_12 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001969 263.0
HKD3_k127_7269146_13 Protein of unknown function (DUF4080) K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000001033 201.0
HKD3_k127_7269146_14 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000008119 162.0
HKD3_k127_7269146_15 EamA-like transporter family - - - 0.0000000000000000000000000000005781 136.0
HKD3_k127_7269146_16 Domain of unknown function DUF302 - - - 0.00000000000000000268 90.0
HKD3_k127_7269146_17 Histidine kinase - - - 0.0000000000000002146 90.0
HKD3_k127_7269146_18 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000006766 78.0
HKD3_k127_7269146_19 Preprotein translocase SecG subunit K03075 - - 0.00000000000008366 75.0
HKD3_k127_7269146_2 ABC transporter, ATP-binding protein K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 456.0
HKD3_k127_7269146_20 Elongator protein 3, MiaB family, Radical SAM K06139 - - 0.000006125 58.0
HKD3_k127_7269146_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009875 460.0
HKD3_k127_7269146_4 PFAM Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 434.0
HKD3_k127_7269146_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 389.0
HKD3_k127_7269146_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002262 310.0
HKD3_k127_7269146_7 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 305.0
HKD3_k127_7269146_8 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000492 291.0
HKD3_k127_7269146_9 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006767 298.0
HKD3_k127_7297512_0 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K01563,K04075,K11991 - 3.5.4.1,3.5.4.33,3.8.1.5,6.3.4.19 0.000000000000000000000000000000000000000000000000000000001141 205.0
HKD3_k127_7297512_1 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000001707 181.0
HKD3_k127_7297512_2 Resolvase, N terminal domain - - - 0.00001962 50.0
HKD3_k127_7301665_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1119.0
HKD3_k127_7301665_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.892e-260 814.0
HKD3_k127_7301665_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 286.0
HKD3_k127_7301665_3 IA, variant 3 K06019 - 3.6.1.1 0.00000000000000000000000000000000000000000000001517 183.0
HKD3_k127_7301665_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000237 150.0
HKD3_k127_7301665_5 Major facilitator superfamily - - - 0.00000000000000000000000000000000000001974 160.0
HKD3_k127_7301665_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000004707 72.0
HKD3_k127_7301665_7 FtsX-like permease family K02004 - - 0.00003948 52.0
HKD3_k127_7301665_8 Protein of unknown function (DUF721) - - - 0.0002248 52.0
HKD3_k127_7382277_0 Heat shock 70 kDa protein K04043 - - 1.146e-300 937.0
HKD3_k127_7382277_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 485.0
HKD3_k127_7382277_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 323.0
HKD3_k127_7382277_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000005123 141.0
HKD3_k127_7382277_4 Transcriptional regulator, MerR family K13640 - - 0.000000000000000000000000000609 119.0
HKD3_k127_7382277_5 4Fe-4S binding domain - - - 0.000000000000000000004804 94.0
HKD3_k127_7382277_6 - - - - 0.000001175 55.0
HKD3_k127_7384293_0 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000003344 225.0
HKD3_k127_7384293_1 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000002709 205.0
HKD3_k127_7384293_2 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000003847 162.0
HKD3_k127_7384293_3 Chemotaxis signal transduction protein K03408 - - 0.000000000000000000000000009131 119.0
HKD3_k127_7384293_4 Putative peptidoglycan binding domain - - - 0.000000000000000000000001065 121.0
HKD3_k127_7384293_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000003629 91.0
HKD3_k127_7384293_6 Fibronectin type III domain protein - - - 0.0000001263 66.0
HKD3_k127_7384293_7 gluconolactonase activity K14274 - - 0.0000003148 63.0
HKD3_k127_7384293_8 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000004537 61.0
HKD3_k127_7500425_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 364.0
HKD3_k127_7500425_1 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000000000000000000000000000009216 200.0
HKD3_k127_7500425_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000458 168.0
HKD3_k127_7500425_3 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000005009 109.0
HKD3_k127_7500425_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000001718 59.0
HKD3_k127_7594078_0 Belongs to the peptidase S8 family K14743 - - 0.000000000000000000000000000000000000000000000001196 198.0
HKD3_k127_7594078_1 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000000000000006955 119.0
HKD3_k127_7594078_2 - - - - 0.00000000000000001044 85.0
HKD3_k127_7594078_3 Belongs to the NAD(P)-dependent epimerase dehydratase family - - - 0.0000000003204 60.0
HKD3_k127_7637813_0 TIGRFAM DNA polymerase III, alpha subunit K02337,K14162 - 2.7.7.7 1.335e-222 730.0
HKD3_k127_7637813_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 376.0
HKD3_k127_7637813_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000001042 224.0
HKD3_k127_7637813_3 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000000000000000000000000001729 158.0
HKD3_k127_7640456_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 405.0
HKD3_k127_7640456_1 RecQ zinc-binding K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 369.0
HKD3_k127_7640456_2 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000001342 191.0
HKD3_k127_7640456_3 Histidine triad domain protein K02503 - - 0.000000000000000000000000000000000007071 146.0
HKD3_k127_7640456_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000001338 74.0
HKD3_k127_7708400_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 314.0
HKD3_k127_7708400_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000009204 191.0
HKD3_k127_7708400_2 Belongs to the anti-sigma-factor antagonist family K04749 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000368 123.0
HKD3_k127_7708400_3 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000002524 66.0
HKD3_k127_7708400_4 Twin arginine-targeting protein translocase, TatA E family K03117,K03646 - - 0.0000001687 59.0
HKD3_k127_7708400_5 antisigma factor binding K04749,K17763,K20978 - - 0.0000002343 58.0
HKD3_k127_7708400_6 Glycosyltransferase like family - - - 0.0005064 52.0
HKD3_k127_7732952_0 WG containing repeat - - - 0.000000000000000000000000000000000000000000000000008362 195.0
HKD3_k127_7732952_1 Kinase domain K12132 - 2.7.11.1 0.00000001294 64.0
HKD3_k127_7766305_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 342.0
HKD3_k127_7766305_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000002237 242.0
HKD3_k127_7766305_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000005422 213.0
HKD3_k127_7766305_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000001052 162.0
HKD3_k127_7766305_4 ATP cob(I)alamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000008577 120.0
HKD3_k127_7769722_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 402.0
HKD3_k127_7769722_1 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 324.0
HKD3_k127_7769722_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000007054 219.0
HKD3_k127_7769722_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000009757 218.0
HKD3_k127_7769722_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000003046 161.0
HKD3_k127_7769722_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.6.1.9 0.0000002514 55.0
HKD3_k127_7780340_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 469.0
HKD3_k127_7780340_1 quinolinate synthetase A activity K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0030312,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 338.0
HKD3_k127_7780340_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 309.0
HKD3_k127_7780340_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001311 284.0
HKD3_k127_7780340_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000008718 108.0
HKD3_k127_7824333_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 332.0
HKD3_k127_7824333_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 297.0
HKD3_k127_7824333_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000001061 228.0
HKD3_k127_7824333_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000002545 200.0
HKD3_k127_7824333_4 Beta-lactamase - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000000000000000000000000007191 134.0
HKD3_k127_7878127_0 Belongs to the SEDS family - - - 4.636e-249 798.0
HKD3_k127_7878127_1 Kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 454.0
HKD3_k127_7878127_2 phosphatase 2C K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 313.0
HKD3_k127_7878127_3 Kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000141 263.0
HKD3_k127_7878127_4 Protein of unknown function (DUF2662) - - - 0.0000000000000000000000000000000000003981 150.0
HKD3_k127_7878127_5 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000009778 138.0
HKD3_k127_7878127_6 positive regulation of acetylcholine metabolic process K06910 - - 0.00000000000000000000000000000003498 140.0
HKD3_k127_7878127_7 Inner membrane component of T3SS, cytoplasmic domain - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.00000000000002328 78.0
HKD3_k127_7878127_8 - - - - 0.0007 43.0
HKD3_k127_7966545_0 TIGRFAM cell envelope-related function transcriptional attenuator - - - 0.0000000000000000000000000000000000000000000000000000000000000000202 243.0
HKD3_k127_7966545_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000003485 226.0
HKD3_k127_7966545_2 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000002188 208.0
HKD3_k127_7966545_3 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000001312 104.0
HKD3_k127_797997_0 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 313.0
HKD3_k127_797997_1 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009575 288.0
HKD3_k127_797997_2 Type II secretion system (T2SS), protein F K12510 - - 0.00000000000000000000000000000000000000000000000000000000000001551 235.0
HKD3_k127_797997_3 Type II secretion system K12511 - - 0.000000000000000000000000000000000000000000000000000000001018 212.0
HKD3_k127_797997_4 oligosaccharyl transferase activity - - - 0.000000000000000000000000000000000000000000003086 185.0
HKD3_k127_797997_5 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000003447 139.0
HKD3_k127_8055844_0 - - - - 0.00000000177 59.0
HKD3_k127_8055844_1 cell wall anchor domain - - - 0.00000001404 67.0
HKD3_k127_8055844_2 Pfam:N_methyl_2 - - - 0.0000007441 61.0
HKD3_k127_8110455_0 Elongation factor SelB winged helix K03833 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 574.0
HKD3_k127_8110455_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 470.0
HKD3_k127_8110455_2 denitrification pathway - - - 0.0000000000000000000003529 108.0
HKD3_k127_8110455_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000006548 75.0
HKD3_k127_8123280_0 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004473 303.0
HKD3_k127_8123280_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000001078 236.0
HKD3_k127_8123280_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000001504 129.0
HKD3_k127_8174326_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 416.0
HKD3_k127_8174326_1 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 369.0
HKD3_k127_8174326_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 351.0
HKD3_k127_8174326_3 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000003706 130.0
HKD3_k127_8174326_4 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000003734 74.0
HKD3_k127_8174326_5 NAD(P)H-binding - - - 0.00000000493 62.0
HKD3_k127_8297079_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 392.0
HKD3_k127_8297079_1 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 347.0
HKD3_k127_8297079_10 YGGT family K02221 - - 0.0000000005288 69.0
HKD3_k127_8297079_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 327.0
HKD3_k127_8297079_3 phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001228 286.0
HKD3_k127_8297079_4 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 GO:0000287,GO:0003674,GO:0003824,GO:0004735,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019752,GO:0030145,GO:0040007,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000001151 213.0
HKD3_k127_8297079_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000009582 205.0
HKD3_k127_8297079_6 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.000000000000000000000000000000000000000000007404 173.0
HKD3_k127_8297079_7 Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA K09772 - - 0.00000000000000000000000000000000008495 141.0
HKD3_k127_8297079_8 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000002634 129.0
HKD3_k127_8297079_9 DivIVA domain protein K04074 - - 0.0000000000000000000000000001333 120.0
HKD3_k127_8322425_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1006.0
HKD3_k127_8322425_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 301.0
HKD3_k127_8322425_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005075 265.0
HKD3_k127_8322425_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000001479 223.0
HKD3_k127_8322425_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000002736 159.0
HKD3_k127_8396870_0 Histidine kinase - - - 0.000000000000000000000000000000000001206 158.0
HKD3_k127_8396870_1 response regulator - - - 0.00000000000000000000000000000000006926 141.0
HKD3_k127_8396870_2 GAF domain K02480 - 2.7.13.3 0.0000000000000000000000000003378 129.0
HKD3_k127_8396870_3 Histidine kinase - - - 0.0001116 51.0
HKD3_k127_841181_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.791e-204 643.0
HKD3_k127_841181_1 MazG family K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001323 273.0
HKD3_k127_841181_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000004052 59.0
HKD3_k127_8437066_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.787e-222 706.0
HKD3_k127_8437066_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 612.0
HKD3_k127_8437066_2 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000001445 238.0
HKD3_k127_8437066_3 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.00000000000000000000000000000000007317 148.0
HKD3_k127_8437066_4 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.000000000000000000000000000003599 134.0
HKD3_k127_8456848_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.312e-209 657.0
HKD3_k127_8456848_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000004461 263.0
HKD3_k127_8456848_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000002812 224.0
HKD3_k127_8456848_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000152 162.0
HKD3_k127_8468225_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 456.0
HKD3_k127_8468225_1 Domain of unknown function (DUF1508) K09946 - - 0.00000000000000000000000000000000000307 141.0
HKD3_k127_8468225_2 transcriptional regulator - - - 0.00000000000000000005105 98.0
HKD3_k127_8468225_3 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000002886 87.0
HKD3_k127_8472432_0 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 300.0
HKD3_k127_8472432_1 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000008766 175.0
HKD3_k127_8472432_2 Major facilitator Superfamily K03291 - - 0.0000000000000000000000000000000000000000105 171.0
HKD3_k127_849072_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 496.0
HKD3_k127_849072_1 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000001264 256.0
HKD3_k127_849072_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000395 233.0
HKD3_k127_849072_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03088,K03091,K12296 - - 0.000000000000000000000000000000000000000000000000000000000000005407 224.0
HKD3_k127_849072_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000001877 156.0
HKD3_k127_849072_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000001094 110.0
HKD3_k127_849072_6 NACHT domain - - - 0.0000000000000004961 92.0
HKD3_k127_849072_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000001409 65.0
HKD3_k127_849072_8 protein folding in endoplasmic reticulum K19134 - - 0.0000000002355 71.0
HKD3_k127_849072_9 Evidence 5 No homology to any previously reported sequences - - - 0.000001239 52.0
HKD3_k127_8523174_0 - - - - 0.00000000000000009939 84.0
HKD3_k127_8523174_1 cell wall binding repeat - - - 0.00000000000001081 85.0
HKD3_k127_8564252_0 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 360.0
HKD3_k127_8564252_1 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 296.0
HKD3_k127_8564252_2 signal peptide peptidase SppA, 36K type K04773 - - 0.0000000000000000000000000000000000000000000000000000005936 202.0
HKD3_k127_8564252_3 2-phosphoglycerate kinase K05715 - - 0.0000000000000000000000000000000004179 151.0
HKD3_k127_8575701_0 Cysteine desulfurase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 350.0
HKD3_k127_8575701_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 329.0
HKD3_k127_8575701_10 Prokaryotic cytochrome b561 - - - 0.000000000000001679 87.0
HKD3_k127_8575701_11 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000003473 58.0
HKD3_k127_8575701_13 Tetratricopeptide repeat - - - 0.00004407 55.0
HKD3_k127_8575701_2 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000009577 212.0
HKD3_k127_8575701_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000001195 192.0
HKD3_k127_8575701_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000002745 197.0
HKD3_k127_8575701_5 TIGRFAM molybdenum cofactor synthesis - - - 0.0000000000000000000000000000000000000000001404 172.0
HKD3_k127_8575701_6 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000002265 168.0
HKD3_k127_8575701_7 formate dehydrogenase - - - 0.0000000000000000000000323 114.0
HKD3_k127_8575701_8 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000001727 94.0
HKD3_k127_8575701_9 Cytochrome c7 and related cytochrome c - - - 0.0000000000000006831 91.0
HKD3_k127_8583648_0 M42 glutamyl aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 432.0
HKD3_k127_8583648_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000131 117.0
HKD3_k127_8583648_2 protein containing a NRPS condensation (Elongation) domain - - - 0.000000000000001312 86.0
HKD3_k127_8607675_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 364.0
HKD3_k127_8607675_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 324.0
HKD3_k127_8607675_2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
HKD3_k127_8607675_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000003761 227.0
HKD3_k127_8607675_4 mitochondrial genome maintenance K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000005088 134.0
HKD3_k127_8612781_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1307.0
HKD3_k127_8612781_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 391.0
HKD3_k127_8612781_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001827 246.0
HKD3_k127_8612781_3 ABC-type transport system involved in lipoprotein release permease component K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000002645 246.0
HKD3_k127_8612781_4 Cobalamin B12-binding domain protein - - - 0.0000000000000000008357 97.0
HKD3_k127_8617244_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0008150,GO:0009605,GO:0009607,GO:0016020,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136 - 5.018e-272 854.0
HKD3_k127_8617244_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 466.0
HKD3_k127_8617244_2 NmrA-like family K01709,K01710,K01784 - 4.2.1.45,4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 383.0
HKD3_k127_8617244_3 Ribosomal protein S1 K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 329.0
HKD3_k127_8617244_4 Glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 308.0
HKD3_k127_8617244_5 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000002454 233.0
HKD3_k127_8617244_6 sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000159 218.0
HKD3_k127_8617244_7 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000005287 151.0
HKD3_k127_8617244_8 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000000000000000000000000000007063 130.0
HKD3_k127_8638972_0 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 413.0
HKD3_k127_8638972_1 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008427 279.0
HKD3_k127_8638972_2 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000002995 260.0
HKD3_k127_8638972_3 Prephenate dehydratase K04518,K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002716 269.0
HKD3_k127_8638972_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000002637 193.0
HKD3_k127_8638972_5 Protein of unknown function (DUF4446) - - - 0.000000000000003418 83.0
HKD3_k127_8661927_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.296e-245 771.0
HKD3_k127_8661927_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.989e-222 697.0
HKD3_k127_8661927_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000001079 238.0
HKD3_k127_8661927_3 ATP synthase subunit C K02124 - - 0.0000000000000000000000000167 126.0
HKD3_k127_8661927_4 subunit c K02119 - - 0.00000000000000000000000001686 123.0
HKD3_k127_8661927_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000001255 72.0
HKD3_k127_8661927_6 Bacterial protein of unknown function (DUF951) - - - 0.0000000000002162 84.0
HKD3_k127_8661927_7 Psort location Cytoplasmic, score 8.87 K02122 - - 0.0000000003503 66.0
HKD3_k127_8661927_9 protein secretion K20276 - - 0.00002351 57.0
HKD3_k127_8924442_0 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000003025 211.0
HKD3_k127_8971343_0 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000007227 151.0
HKD3_k127_8993144_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 503.0
HKD3_k127_8993144_1 Amino acid kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 295.0
HKD3_k127_8993144_2 DegV family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007359 258.0
HKD3_k127_8993144_3 TIGRFAM degV family protein - - - 0.00000000000000000000000000000000000000000000000000000000003511 218.0
HKD3_k127_8993144_4 transferase activity, transferring glycosyl groups K20444 - - 0.00000000000000000000000000000000000000002362 169.0
HKD3_k127_8993144_5 calcium- and calmodulin-responsive adenylate cyclase activity K08372 - - 0.00000000000000000000000000000000001222 158.0
HKD3_k127_8993144_6 protein related to plant photosystem II stability assembly factor - - - 0.0000000000001279 86.0
HKD3_k127_8993144_7 Uncharacterized ACR, COG1430 K09005 - - 0.0000000001098 74.0
HKD3_k127_8993144_8 Pregnancy-associated plasma protein-A - - - 0.000007492 60.0
HKD3_k127_8993144_9 - - - - 0.0007801 47.0
HKD3_k127_8996689_0 Clp domain protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1137.0
HKD3_k127_8996689_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 320.0
HKD3_k127_8996689_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000001879 113.0
HKD3_k127_902917_0 domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000001297 136.0
HKD3_k127_902917_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000003086 142.0
HKD3_k127_9059236_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 449.0
HKD3_k127_9059236_1 SLBB domain K02237 - - 0.000000000000000000000000000000000003386 145.0
HKD3_k127_9089798_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 316.0
HKD3_k127_9089798_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 319.0
HKD3_k127_9089798_2 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000006832 246.0
HKD3_k127_9089798_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000003995 136.0
HKD3_k127_9116295_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 436.0
HKD3_k127_9116295_1 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 329.0
HKD3_k127_9116295_2 aminopeptidase activity K19701,K19702 - 3.4.11.10,3.4.11.24,3.4.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 314.0
HKD3_k127_9116295_3 Phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000001213 239.0
HKD3_k127_9116295_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000007889 50.0
HKD3_k127_9146390_0 DNA topoisomerase K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 361.0
HKD3_k127_9146390_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.00000000000000000000000000000000000000000000000000006717 192.0
HKD3_k127_9146390_2 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000002852 169.0
HKD3_k127_9154686_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.801e-219 691.0
HKD3_k127_9154686_1 Sortase family - - - 0.00000000000000000000000000000000001626 145.0
HKD3_k127_9154686_2 NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000744 127.0
HKD3_k127_9231022_0 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.452e-277 867.0
HKD3_k127_9231022_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.007e-258 832.0
HKD3_k127_9231022_10 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 331.0
HKD3_k127_9231022_11 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 291.0
HKD3_k127_9231022_12 PFAM glutamate synthase alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001912 286.0
HKD3_k127_9231022_13 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002734 266.0
HKD3_k127_9231022_14 Signal transduction histidine kinase K00936 GO:0000155,GO:0000160,GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005524,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035556,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006066 269.0
HKD3_k127_9231022_15 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000782 235.0
HKD3_k127_9231022_16 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000002233 237.0
HKD3_k127_9231022_17 Response regulator receiver K22010 GO:0000160,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0007154,GO:0007165,GO:0008150,GO:0009987,GO:0016020,GO:0023052,GO:0030312,GO:0035556,GO:0040007,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000001539 231.0
HKD3_k127_9231022_18 TIGRFAM methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000000000000007029 223.0
HKD3_k127_9231022_19 Transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000002097 207.0
HKD3_k127_9231022_2 Belongs to the glutamate synthase family K00265 - 1.4.1.13,1.4.1.14 1.298e-219 713.0
HKD3_k127_9231022_20 PFAM Class II aldolase K01628 - 4.1.2.17 0.000000000000000000000000000000000000000003243 164.0
HKD3_k127_9231022_21 HD domain - - - 0.000000000000000000000000000000000001284 155.0
HKD3_k127_9231022_22 Ribosomal protein S1 K02945 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000001285 121.0
HKD3_k127_9231022_23 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000001273 115.0
HKD3_k127_9231022_24 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000008569 114.0
HKD3_k127_9231022_25 D-glucuronyl C5-epimerase C-terminus - - - 0.000000000000000000003116 108.0
HKD3_k127_9231022_26 Cytochrome C oxidase, cbb3-type, subunit III K02275 - 1.9.3.1 0.00000000000000000007659 97.0
HKD3_k127_9231022_27 transcriptional regulator, Rrf2 family - - - 0.000000000000005276 80.0
HKD3_k127_9231022_28 PBS lyase HEAT-like repeat - - - 0.000000000000008989 85.0
HKD3_k127_9231022_29 membrane - - - 0.0000000000001433 79.0
HKD3_k127_9231022_3 Glutamine synthetase, beta-grasp domain K01915 - 6.3.1.2 1.974e-200 634.0
HKD3_k127_9231022_30 - - - - 0.000002139 60.0
HKD3_k127_9231022_31 Short C-terminal domain K08982 - - 0.0002171 48.0
HKD3_k127_9231022_4 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 553.0
HKD3_k127_9231022_5 Glutamate synthase (NADPH) GltB1 subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 459.0
HKD3_k127_9231022_6 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 454.0
HKD3_k127_9231022_7 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 427.0
HKD3_k127_9231022_8 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 422.0
HKD3_k127_9231022_9 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009333,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 338.0
HKD3_k127_9285796_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 411.0
HKD3_k127_9285796_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000002969 142.0
HKD3_k127_938331_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 592.0
HKD3_k127_938331_1 Aconitase C-terminal domain K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000001175 244.0
HKD3_k127_938331_2 Polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000002952 230.0
HKD3_k127_9436960_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 574.0
HKD3_k127_9436960_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 419.0
HKD3_k127_9436960_10 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000002081 87.0
HKD3_k127_9436960_11 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000006554 81.0
HKD3_k127_9436960_12 Cytochrome b/b6/petB K03620 - - 0.0000000000006027 71.0
HKD3_k127_9436960_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 416.0
HKD3_k127_9436960_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 396.0
HKD3_k127_9436960_4 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000001215 209.0
HKD3_k127_9436960_5 Involved in cell wall K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000003889 205.0
HKD3_k127_9436960_6 - - - - 0.000000000000000000000000000000000000000000001771 188.0
HKD3_k127_9436960_7 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000002238 171.0
HKD3_k127_9436960_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000000000000000000000662 134.0
HKD3_k127_9436960_9 OsmC-like protein K07397 - - 0.00000000000000000000000000000008956 130.0
HKD3_k127_9449827_0 Threonine synthase K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 608.0
HKD3_k127_9449827_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 496.0
HKD3_k127_9449827_2 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 404.0
HKD3_k127_9449827_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 366.0
HKD3_k127_9449827_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000003355 203.0
HKD3_k127_9449827_5 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000005959 148.0
HKD3_k127_9449827_6 negative regulation of transcription, DNA-templated - - - 0.000000000000000000000000000000002016 138.0
HKD3_k127_9449827_7 NIL domain - - - 0.0000000000000000000000000000000306 129.0
HKD3_k127_9503180_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.984e-290 906.0
HKD3_k127_9503180_1 PFAM Signal transduction histidine kinase, osmosensitive K channel sensor, N-terminal K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001133 275.0
HKD3_k127_9503180_2 K+-transporting ATPase, c chain K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000002617 191.0
HKD3_k127_9503180_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000002475 160.0
HKD3_k127_96768_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 2.732e-257 824.0
HKD3_k127_96768_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 417.0
HKD3_k127_96768_10 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000001503 132.0
HKD3_k127_96768_11 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000001775 134.0
HKD3_k127_96768_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000000000001402 120.0
HKD3_k127_96768_13 superoxide reductase activity K05919 - 1.15.1.2 0.0000000000000005154 85.0
HKD3_k127_96768_14 Preprotein translocase K03210 - - 0.000000000000002244 79.0
HKD3_k127_96768_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 392.0
HKD3_k127_96768_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 384.0
HKD3_k127_96768_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 338.0
HKD3_k127_96768_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001505 282.0
HKD3_k127_96768_6 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004526 249.0
HKD3_k127_96768_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000001875 171.0
HKD3_k127_96768_8 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.000000000000000000000000000000000000007614 156.0
HKD3_k127_96768_9 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000002011 144.0