Overview

ID MAG01859
Name HKD3_bin.48
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Casimicrobiaceae
Genus VBCG01
Species
Assembly information
Completeness (%) 72.57
Contamination (%) 4.39
GC content (%) 71.0
N50 (bp) 9,518
Genome size (bp) 3,695,003

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3636

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1202999_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 9.919e-199 632.0
HKD3_k127_1202999_1 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 491.0
HKD3_k127_1202999_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.0000000000000000000000000000000000000000000000009286 184.0
HKD3_k127_1202999_11 - - - - 0.000000000000000000000152 109.0
HKD3_k127_1202999_2 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 434.0
HKD3_k127_1202999_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 407.0
HKD3_k127_1202999_4 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009402 370.0
HKD3_k127_1202999_5 dehydrogenase K13775 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 345.0
HKD3_k127_1202999_6 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000005545 250.0
HKD3_k127_1202999_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000001411 211.0
HKD3_k127_1202999_8 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000000000000000007623 199.0
HKD3_k127_1202999_9 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000001799 197.0
HKD3_k127_1205724_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 521.0
HKD3_k127_1213008_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 1.175e-220 695.0
HKD3_k127_1213008_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.851e-195 622.0
HKD3_k127_1213008_10 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.000000000000000000000000000000000000000000000000002381 183.0
HKD3_k127_1213008_11 DNA-binding transcription factor activity - - - 0.00000000000000000000000000004209 123.0
HKD3_k127_1213008_12 HIUase/Transthyretin family K07127 - 3.5.2.17 0.000000000000000000000001041 109.0
HKD3_k127_1213008_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 521.0
HKD3_k127_1213008_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 486.0
HKD3_k127_1213008_4 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 469.0
HKD3_k127_1213008_5 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10112 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015169,GO:0015399,GO:0015405,GO:0015430,GO:0015605,GO:0015711,GO:0015748,GO:0015794,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1901264,GO:1901505 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
HKD3_k127_1213008_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 355.0
HKD3_k127_1213008_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 320.0
HKD3_k127_1213008_8 PFAM Integral membrane protein TerC - - - 0.000000000000000000000000000000000000000000000000000001273 197.0
HKD3_k127_1213008_9 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000001224 196.0
HKD3_k127_1219009_0 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 533.0
HKD3_k127_1219009_1 PFAM polysaccharide deacetylase K01452 - 3.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 505.0
HKD3_k127_1219009_10 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000001425 233.0
HKD3_k127_1219009_11 2-keto-3-deoxy-galactonokinase K00883 - 2.7.1.58 0.00000000000000000000000000000000000000000000000000000000000007736 224.0
HKD3_k127_1219009_12 Molybdopterin guanine dinucleotide synthesis protein B K03753 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000003748 208.0
HKD3_k127_1219009_13 OHCU decarboxylase K13485 - 4.1.1.97 0.000000000000000000000000000000000000000000000001704 196.0
HKD3_k127_1219009_14 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.00000000000000000000000000000000000000000000001835 174.0
HKD3_k127_1219009_15 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000004732 159.0
HKD3_k127_1219009_16 - - - - 0.000000000000000000000000000000000000001866 156.0
HKD3_k127_1219009_17 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K10003 - - 0.00000000000000000000000000000000009536 136.0
HKD3_k127_1219009_18 Copper resistance protein D - - - 0.00000000000000000000000000000133 131.0
HKD3_k127_1219009_19 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000008555 126.0
HKD3_k127_1219009_2 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 500.0
HKD3_k127_1219009_20 - - - - 0.00000000000000000000000005738 123.0
HKD3_k127_1219009_21 SnoaL-like domain - - - 0.00000000000000000000005964 104.0
HKD3_k127_1219009_22 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.000000000000008309 80.0
HKD3_k127_1219009_24 OmpA-like transmembrane domain - - - 0.000004788 57.0
HKD3_k127_1219009_25 protein import - - - 0.000004827 59.0
HKD3_k127_1219009_3 Extracellular solute-binding protein family 3 K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 434.0
HKD3_k127_1219009_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009583 420.0
HKD3_k127_1219009_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 396.0
HKD3_k127_1219009_6 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001701 269.0
HKD3_k127_1219009_7 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001231 276.0
HKD3_k127_1219009_8 Aldolase K01631 - 4.1.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000008896 253.0
HKD3_k127_1219009_9 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001725 249.0
HKD3_k127_1219827_0 AcrB/AcrD/AcrF family K07787 - - 9.544e-236 738.0
HKD3_k127_1219827_1 PFAM Blue (type 1) copper domain - - - 0.00000000000000000000000000000000000000000000006042 180.0
HKD3_k127_1219827_2 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000002701 113.0
HKD3_k127_1219827_3 - - - - 0.0000000000000000000000007694 121.0
HKD3_k127_1219827_4 Subtilase family K14645 - - 0.0000000000000007047 90.0
HKD3_k127_1220407_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 289.0
HKD3_k127_1220407_1 NADPH-dependent FMN reductase K19784 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002079 264.0
HKD3_k127_1220407_2 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000003337 117.0
HKD3_k127_1220407_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000033 57.0
HKD3_k127_1221918_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008457 465.0
HKD3_k127_1221918_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 450.0
HKD3_k127_1221918_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 397.0
HKD3_k127_1221918_3 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 350.0
HKD3_k127_1221918_4 phenazine biosynthesis protein PhzF family - - - 0.0000000000000000000000000007405 114.0
HKD3_k127_1221918_5 Competence protein K02237 - - 0.0000000000000000004987 101.0
HKD3_k127_1222788_0 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 534.0
HKD3_k127_1222788_1 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 287.0
HKD3_k127_1222788_2 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.00000000000000000000000000000000000000000005226 160.0
HKD3_k127_1222788_3 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.000000007509 60.0
HKD3_k127_1237096_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 550.0
HKD3_k127_1237096_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 488.0
HKD3_k127_1237096_10 RHS Repeat - - - 0.000000000000000000000000000000000000000000000000008598 209.0
HKD3_k127_1237096_11 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000002434 183.0
HKD3_k127_1237096_12 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000007235 189.0
HKD3_k127_1237096_13 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000006391 152.0
HKD3_k127_1237096_14 Zinc metalloprotease (Elastase) K01186,K05994,K21449 - 3.2.1.18,3.4.11.10 0.0000000000000000000000000000000000008349 161.0
HKD3_k127_1237096_15 Dodecin K09165 - - 0.000000000000000000000000000003346 121.0
HKD3_k127_1237096_16 Invasion gene expression up-regulator SirB - - - 0.000000000000000000000000000009395 123.0
HKD3_k127_1237096_17 PFAM Cyclic nucleotide-binding K21563 - - 0.000000000009522 69.0
HKD3_k127_1237096_18 Subtilase family - - - 0.00009412 53.0
HKD3_k127_1237096_2 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 340.0
HKD3_k127_1237096_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 350.0
HKD3_k127_1237096_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007074 328.0
HKD3_k127_1237096_5 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 311.0
HKD3_k127_1237096_6 protein, hemolysin III K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 311.0
HKD3_k127_1237096_7 FIST N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 303.0
HKD3_k127_1237096_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000001311 237.0
HKD3_k127_1237096_9 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000222 206.0
HKD3_k127_1240816_0 PFAM ABC transporter K06158 - - 3.399e-202 647.0
HKD3_k127_1240816_1 Major facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 516.0
HKD3_k127_1240816_2 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 372.0
HKD3_k127_1240816_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 368.0
HKD3_k127_1240816_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000201 284.0
HKD3_k127_1240816_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000005356 235.0
HKD3_k127_1240816_6 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000003156 209.0
HKD3_k127_1240816_7 Domain of unknown function (DUF4124) - - - 0.00000000000007311 80.0
HKD3_k127_1264476_0 Abc transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 407.0
HKD3_k127_1264476_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001623 302.0
HKD3_k127_1264476_2 COG0845 Membrane-fusion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002345 284.0
HKD3_k127_1264476_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000002802 172.0
HKD3_k127_1264476_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0000000000000000000000000000000000000004468 152.0
HKD3_k127_1271055_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 454.0
HKD3_k127_1271055_1 PFAM bifunctional deaminase-reductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 321.0
HKD3_k127_1271055_11 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000007527 118.0
HKD3_k127_1271055_12 Transcription factor zinc-finger K09981 - - 0.0000002552 62.0
HKD3_k127_1271055_2 Protein of unknown function (DUF4256) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008045 255.0
HKD3_k127_1271055_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000164 228.0
HKD3_k127_1271055_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000008805 225.0
HKD3_k127_1271055_5 Chloramphenicol phosphotransferase-like protein K18554 - - 0.0000000000000000000000000000000000000000000000000000000004872 209.0
HKD3_k127_1271055_6 PFAM Acetyltransferase (GNAT) family K03395 - 2.3.1.60 0.0000000000000000000000000000000000000000000000000000000008768 208.0
HKD3_k127_1271055_7 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000001793 191.0
HKD3_k127_1271055_8 YCII-related domain - - - 0.0000000000000000000000000000000000000000000000000004132 189.0
HKD3_k127_1271055_9 COGs COG1670 Acetyltransferase including N-acetylase of ribosomal protein - - - 0.00000000000000000000000000000000000000001784 160.0
HKD3_k127_1273545_0 ABC transporter substrate-binding protein K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 584.0
HKD3_k127_1273545_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 482.0
HKD3_k127_1273545_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000001089 215.0
HKD3_k127_1273545_3 Succinylglutamate desuccinylase - - - 0.000000000000000000000000000000000000000000172 181.0
HKD3_k127_1287451_0 DnaJ molecular chaperone homology domain K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 449.0
HKD3_k127_1287451_1 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 386.0
HKD3_k127_1287451_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000001323 231.0
HKD3_k127_1287451_3 calcium- and calmodulin-responsive adenylate cyclase activity K01406 - 3.4.24.40 0.000000000000000000000000000000000000000000000000000001038 207.0
HKD3_k127_1287451_4 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000000000000000000000000000000000006088 173.0
HKD3_k127_1287451_5 MerR HTH family regulatory protein K18997 - - 0.00000001223 57.0
HKD3_k127_1287451_6 PBS lyase - - - 0.0006222 52.0
HKD3_k127_1291555_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1155.0
HKD3_k127_1291555_1 Competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 623.0
HKD3_k127_1291555_2 Catalyzes the cleavage of L-allo-threonine and L- threonine to glycine and acetaldehyde K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 382.0
HKD3_k127_1291555_3 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000001104 201.0
HKD3_k127_1291555_4 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000001088 203.0
HKD3_k127_1291555_5 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000000779 206.0
HKD3_k127_1291555_6 - - - - 0.00000000000000000000000000000000000001725 147.0
HKD3_k127_1291555_7 - - - - 0.000000000000000000000000000001531 128.0
HKD3_k127_1291555_8 Glycosyl hydrolases family 16 - - - 0.0004571 53.0
HKD3_k127_1292439_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 450.0
HKD3_k127_1292439_1 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.0000001012 56.0
HKD3_k127_1303543_0 Dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 395.0
HKD3_k127_1303543_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 347.0
HKD3_k127_1303543_2 AcrB/AcrD/AcrF family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 326.0
HKD3_k127_1303543_3 PFAM regulatory protein TetR K03577 - - 0.00000000000000000000000000000000000000000000000002846 191.0
HKD3_k127_1313626_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.516e-222 701.0
HKD3_k127_1313626_1 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 613.0
HKD3_k127_1313626_10 - - - - 0.0000001037 62.0
HKD3_k127_1313626_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 492.0
HKD3_k127_1313626_3 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 352.0
HKD3_k127_1313626_4 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 344.0
HKD3_k127_1313626_5 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000002017 212.0
HKD3_k127_1313626_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000008026 201.0
HKD3_k127_1313626_7 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000009691 201.0
HKD3_k127_1313626_8 Transfers a palmitate residue from the sn-1 position of a phospholipid to the N-linked hydroxymyristate on the proximal unit of lipid A or its precursors K12973 - 2.3.1.251 0.000000000000000000000000000000006553 146.0
HKD3_k127_1313626_9 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000007576 102.0
HKD3_k127_1317965_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 7.709e-297 932.0
HKD3_k127_1317965_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003278 289.0
HKD3_k127_1317965_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000001418 261.0
HKD3_k127_1317965_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002259 250.0
HKD3_k127_1317965_4 Isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000002071 208.0
HKD3_k127_1317965_5 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000003209 151.0
HKD3_k127_1317965_6 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000006781 126.0
HKD3_k127_1317965_7 Cytochrome c - - - 0.0000000007581 60.0
HKD3_k127_1319406_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 416.0
HKD3_k127_1319406_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000406 281.0
HKD3_k127_1319406_2 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003523 274.0
HKD3_k127_1319406_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005833 246.0
HKD3_k127_1319406_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000000000000003562 184.0
HKD3_k127_1319406_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000313 156.0
HKD3_k127_1319406_6 Domain of unknown function (DUF1857) - - - 0.000000000000000000000000000001022 127.0
HKD3_k127_1319406_7 - - - - 0.00000000000000000000000002552 118.0
HKD3_k127_1319406_8 - - - - 0.0003683 53.0
HKD3_k127_1334835_0 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 2.023e-215 677.0
HKD3_k127_1334835_1 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 460.0
HKD3_k127_1334835_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004772 407.0
HKD3_k127_1334835_3 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0005538 45.0
HKD3_k127_1379845_0 PFAM alanine racemase domain protein K19967 - 4.1.2.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 404.0
HKD3_k127_1379845_1 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 305.0
HKD3_k127_1379845_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001343 290.0
HKD3_k127_1379845_3 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000001742 225.0
HKD3_k127_1379845_4 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000001465 201.0
HKD3_k127_1387157_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.973e-238 764.0
HKD3_k127_1387157_1 4Fe-4S dicluster domain - - - 1.74e-215 689.0
HKD3_k127_1387157_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 324.0
HKD3_k127_1387157_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000003109 264.0
HKD3_k127_1387157_12 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000001628 229.0
HKD3_k127_1387157_13 transcriptional Regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000004366 234.0
HKD3_k127_1387157_14 cytoplasmic chaperone TorD family protein - - - 0.0000000000000000000000000000000000000007303 157.0
HKD3_k127_1387157_15 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000000000000006362 143.0
HKD3_k127_1387157_16 Domain of unknown function (DUF202) - - - 0.00000000000000000000000007296 120.0
HKD3_k127_1387157_17 Protein of unknown function (DUF3306) - - - 0.0000000000000000000006643 112.0
HKD3_k127_1387157_18 - - - - 0.0000000000000001772 88.0
HKD3_k127_1387157_19 2'-5' RNA ligase superfamily - - - 0.000000000000004581 87.0
HKD3_k127_1387157_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.822e-201 632.0
HKD3_k127_1387157_20 Protein of unknown function (DUF3563) - - - 0.0003561 48.0
HKD3_k127_1387157_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 562.0
HKD3_k127_1387157_4 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 492.0
HKD3_k127_1387157_5 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 488.0
HKD3_k127_1387157_6 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 491.0
HKD3_k127_1387157_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 439.0
HKD3_k127_1387157_8 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 414.0
HKD3_k127_1387157_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 396.0
HKD3_k127_1415616_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.38e-290 898.0
HKD3_k127_1415616_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000002731 257.0
HKD3_k127_1420873_0 Phospholipase D Active site motif K01115 - 3.1.4.4 1.236e-232 741.0
HKD3_k127_1420873_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573,K03183,K07003 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 2.1.1.163,2.1.1.201,2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000002779 258.0
HKD3_k127_1420873_2 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008427 241.0
HKD3_k127_1443233_0 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 3.526e-218 696.0
HKD3_k127_1443233_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.082e-195 624.0
HKD3_k127_1443233_10 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 361.0
HKD3_k127_1443233_11 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009265 334.0
HKD3_k127_1443233_12 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 325.0
HKD3_k127_1443233_13 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 309.0
HKD3_k127_1443233_14 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003771 265.0
HKD3_k127_1443233_15 Tetrapyrrole (Corrin/Porphyrin) Methylases K02303 - 2.1.1.107 0.00000000000000000000000000000000000000000000000000000000000000000005889 240.0
HKD3_k127_1443233_16 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000003701 168.0
HKD3_k127_1443233_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000001797 153.0
HKD3_k127_1443233_18 Tripartite tricarboxylate transporter TctA family - - - 0.0000000000000000000000000000000002704 134.0
HKD3_k127_1443233_19 Transglycosylase associated protein - - - 0.00000000000000001817 90.0
HKD3_k127_1443233_2 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 604.0
HKD3_k127_1443233_20 - - - - 0.000000000001276 76.0
HKD3_k127_1443233_21 Protein of unknown function (DUF2726) - - - 0.0002703 51.0
HKD3_k127_1443233_3 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 576.0
HKD3_k127_1443233_4 Protein of unknown function (DUF993) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 510.0
HKD3_k127_1443233_5 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 490.0
HKD3_k127_1443233_6 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 438.0
HKD3_k127_1443233_7 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 415.0
HKD3_k127_1443233_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 387.0
HKD3_k127_1443233_9 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 365.0
HKD3_k127_1453868_0 Domain of unknown function (DUF3479) K03403 - 6.6.1.1 0.0 1802.0
HKD3_k127_1453868_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.121e-257 809.0
HKD3_k127_1453868_10 Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K04035 - 1.14.13.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 517.0
HKD3_k127_1453868_11 TIGRFAM bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 436.0
HKD3_k127_1453868_12 The reaction center of purple bacteria contains a tightly bound cytochrome molecule which re-reduces the photo oxidized primary electron donor K13992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 422.0
HKD3_k127_1453868_13 Photosynthetic reaction centre, H-chain N-terminal region K13991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 302.0
HKD3_k127_1453868_14 Protein of unknown function (DUF3623) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 286.0
HKD3_k127_1453868_15 TIGRFAM magnesium protoporphyrin O-methyltransferase K03428 - 2.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007906 310.0
HKD3_k127_1453868_16 Bacterial PH domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 241.0
HKD3_k127_1453868_17 PFAM 2-vinyl bacteriochlorophyllide hydratase K11336 - 4.2.1.165 0.0000000000000000000000000000000000000000000000000000000000000185 219.0
HKD3_k127_1453868_18 Bacteriochlorophyll 4-vinyl reductase K04036 - - 0.00000000000000000000000000000000000000000000000000000000000003018 227.0
HKD3_k127_1453868_19 B12-binding - - - 0.00000000000000000000000000000000000000000000000858 184.0
HKD3_k127_1453868_2 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04039 - 1.3.7.7 9.046e-223 707.0
HKD3_k127_1453868_20 Photosynthetic complex assembly protein - - - 0.000000000000000000000000000000000001631 148.0
HKD3_k127_1453868_21 Antenna complex alpha/beta subunit K08926 - - 0.00000000000000000001046 92.0
HKD3_k127_1453868_22 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08927 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000005013 83.0
HKD3_k127_1453868_23 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins - - - 0.00000000004886 77.0
HKD3_k127_1453868_24 - K08927 - - 0.0001137 53.0
HKD3_k127_1453868_3 chlorophyllide reductase subunit Z K11335 - 1.3.7.14,1.3.7.15 1.45e-215 674.0
HKD3_k127_1453868_4 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 2.805e-195 627.0
HKD3_k127_1453868_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 578.0
HKD3_k127_1453868_6 The reaction center is a membrane-bound complex that mediates the initial photochemical event in the electron transfer process of photosynthesis K08929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 558.0
HKD3_k127_1453868_7 Photosynthetic reaction center L subunit K08928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 546.0
HKD3_k127_1453868_8 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 525.0
HKD3_k127_1453868_9 PUCC protein K08226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 547.0
HKD3_k127_14640_0 FAD dependent oxidoreductase central domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 344.0
HKD3_k127_14640_1 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000002304 146.0
HKD3_k127_146773_0 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 458.0
HKD3_k127_146773_1 Transcriptional regulator K03603,K05799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 400.0
HKD3_k127_146773_2 CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 374.0
HKD3_k127_146773_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000002018 235.0
HKD3_k127_146773_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000007511 181.0
HKD3_k127_1468816_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 479.0
HKD3_k127_1468816_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 364.0
HKD3_k127_1468816_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000001165 244.0
HKD3_k127_1468816_3 type 4 pilus biogenesis protein K02656 - - 0.00000000000000000000000000000000000000000000000001353 190.0
HKD3_k127_1468816_4 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000003805 93.0
HKD3_k127_1474779_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.442e-219 698.0
HKD3_k127_1474779_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 554.0
HKD3_k127_1474779_10 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 323.0
HKD3_k127_1474779_11 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 307.0
HKD3_k127_1474779_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004233 276.0
HKD3_k127_1474779_13 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000006684 263.0
HKD3_k127_1474779_14 PFAM VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000004787 247.0
HKD3_k127_1474779_15 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000001067 212.0
HKD3_k127_1474779_16 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.000000000000000000000000000000000000000000000000000000002249 216.0
HKD3_k127_1474779_17 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000002276 196.0
HKD3_k127_1474779_18 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000003755 168.0
HKD3_k127_1474779_19 Belongs to the BolA IbaG family - - - 0.00000000000000000000000002979 111.0
HKD3_k127_1474779_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 400.0
HKD3_k127_1474779_20 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000094 113.0
HKD3_k127_1474779_21 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000002879 102.0
HKD3_k127_1474779_22 STAS domain K07122 - - 0.0001084 54.0
HKD3_k127_1474779_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 396.0
HKD3_k127_1474779_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 392.0
HKD3_k127_1474779_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009856 377.0
HKD3_k127_1474779_6 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 363.0
HKD3_k127_1474779_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 356.0
HKD3_k127_1474779_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 357.0
HKD3_k127_1474779_9 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 342.0
HKD3_k127_1484505_0 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 532.0
HKD3_k127_1484505_1 FAD binding K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 405.0
HKD3_k127_1484505_2 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 0.000000000000000000000000000000000000000000000000000000000000000000000000002858 256.0
HKD3_k127_1484505_3 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000001299 222.0
HKD3_k127_1484505_4 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000001915 184.0
HKD3_k127_1484505_5 acetyltransferase - - - 0.000000000000000000352 96.0
HKD3_k127_1485656_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1319.0
HKD3_k127_1485656_1 PFAM aminotransferase, class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 508.0
HKD3_k127_1485656_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 479.0
HKD3_k127_1485656_3 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 444.0
HKD3_k127_1485656_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 309.0
HKD3_k127_1485656_5 HAD-hyrolase-like K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000006305 244.0
HKD3_k127_1485656_6 OmpA family K03286 - - 0.0000000000000000000000000000000000000000000000000000002985 203.0
HKD3_k127_1485656_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000324 64.0
HKD3_k127_1492809_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.719e-208 656.0
HKD3_k127_1492809_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 536.0
HKD3_k127_1492809_2 phenylacetic acid degradation protein PaaD K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.0000000000000000000000000000000000000000000000000008422 195.0
HKD3_k127_1492809_3 Thiolase, C-terminal domain K00632 - 2.3.1.16 0.00000000000000000000000001345 110.0
HKD3_k127_1492809_4 enoyl-CoA hydratase K15866 - 5.3.3.18 0.000000004148 57.0
HKD3_k127_1519028_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 570.0
HKD3_k127_1519028_1 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000002116 227.0
HKD3_k127_1519028_10 - - - - 0.00000000000003301 83.0
HKD3_k127_1519028_2 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000000000000000000000000000000000000000000001941 234.0
HKD3_k127_1519028_3 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000000000000000000000000000000009916 201.0
HKD3_k127_1519028_4 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.000000000000000000000000000000001102 136.0
HKD3_k127_1519028_5 Hydrogenase-1 expression protein HyaE K03619 - - 0.00000000000000000000000000000001768 133.0
HKD3_k127_1519028_6 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000001732 124.0
HKD3_k127_1519028_7 Hydrogenase/urease nickel incorporation, metallochaperone, hypA K04651 - - 0.0000000000000000000000000002506 125.0
HKD3_k127_1519028_8 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000003555 106.0
HKD3_k127_1519028_9 Hydrogenase expression formation protein hupF K04653 - - 0.0000000000000000004605 98.0
HKD3_k127_1534699_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1251.0
HKD3_k127_1534699_1 COG0437 Fe-S-cluster-containing hydrogenase components 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 329.0
HKD3_k127_1534699_2 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000005365 223.0
HKD3_k127_1534699_3 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000006798 176.0
HKD3_k127_1534699_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000008026 178.0
HKD3_k127_1534699_5 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000000000000004554 151.0
HKD3_k127_1536619_0 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 1.413e-258 814.0
HKD3_k127_1536619_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 352.0
HKD3_k127_1536619_2 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000006334 246.0
HKD3_k127_1536619_3 - - - - 0.0000000000000003543 85.0
HKD3_k127_1544867_0 - - - - 0.00000000000000000000000000000000000000000000000000005414 192.0
HKD3_k127_1544867_1 radical SAM domain protein K03639,K15045 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000006479 204.0
HKD3_k127_1544867_2 Lipopolysaccharide biosynthesis protein - - - 0.0000000000008402 81.0
HKD3_k127_1552642_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 5.022e-320 998.0
HKD3_k127_1552642_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 7.817e-213 687.0
HKD3_k127_1552642_10 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000008548 247.0
HKD3_k127_1552642_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000008684 234.0
HKD3_k127_1552642_12 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000002487 187.0
HKD3_k127_1552642_13 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000003873 171.0
HKD3_k127_1552642_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000005825 130.0
HKD3_k127_1552642_16 Belongs to the frataxin K06202 - - 0.0000000000000000000000000009925 116.0
HKD3_k127_1552642_17 - - - - 0.0000000000000000001113 104.0
HKD3_k127_1552642_2 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00632 - 2.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 546.0
HKD3_k127_1552642_3 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 534.0
HKD3_k127_1552642_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 428.0
HKD3_k127_1552642_5 transglycosylase K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 409.0
HKD3_k127_1552642_6 Glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 356.0
HKD3_k127_1552642_7 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 310.0
HKD3_k127_1552642_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003442 280.0
HKD3_k127_1552642_9 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000002411 263.0
HKD3_k127_1586020_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 7.613e-310 972.0
HKD3_k127_1586020_1 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 511.0
HKD3_k127_1586020_10 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000005379 192.0
HKD3_k127_1586020_11 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000009045 179.0
HKD3_k127_1586020_12 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000001431 136.0
HKD3_k127_1586020_13 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000001329 149.0
HKD3_k127_1586020_14 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000003335 139.0
HKD3_k127_1586020_15 Enoyl-(Acyl carrier protein) reductase K16216 - 1.1.1.320 0.0000000000000000000000000027 121.0
HKD3_k127_1586020_16 TonB C terminal K03646 - - 0.000000000000000000000000007373 118.0
HKD3_k127_1586020_17 - - - - 0.000000000000000000000001535 119.0
HKD3_k127_1586020_18 luxR family K21405 - - 0.00000000000000001189 98.0
HKD3_k127_1586020_2 tRNA wobble cytosine modification - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000799 438.0
HKD3_k127_1586020_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 449.0
HKD3_k127_1586020_4 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 332.0
HKD3_k127_1586020_5 FAD binding domain K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 330.0
HKD3_k127_1586020_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 291.0
HKD3_k127_1586020_7 Disulfide bond isomerase protein N-terminus K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000007653 246.0
HKD3_k127_1586020_8 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003387 251.0
HKD3_k127_1586020_9 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000007538 221.0
HKD3_k127_1598292_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 296.0
HKD3_k127_1598292_1 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003556 249.0
HKD3_k127_1598292_2 acyl-CoA dehydrogenase K06445 - - 0.0000000000000000000000000000000000000002438 155.0
HKD3_k127_160218_0 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 563.0
HKD3_k127_160218_1 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 300.0
HKD3_k127_160218_2 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000006802 131.0
HKD3_k127_160218_3 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000001104 106.0
HKD3_k127_1639776_0 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 437.0
HKD3_k127_1639776_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 422.0
HKD3_k127_1645230_0 2-keto-4-pentenoate hydratase K01617 - 4.1.1.77 0.0000000000000000000000000000000000000000000000000000001011 215.0
HKD3_k127_1645230_1 Belongs to the ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000009987 144.0
HKD3_k127_1645230_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000003043 115.0
HKD3_k127_1645230_3 Sortase (surface protein transpeptidase) K07284 - 3.4.22.70 0.000000004699 59.0
HKD3_k127_1661525_0 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000006307 130.0
HKD3_k127_1661525_1 COG4970 Tfp pilus assembly protein FimT K08084 - - 0.0000000000000000000000000004312 121.0
HKD3_k127_1661525_2 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0000000000000000000000004633 105.0
HKD3_k127_1661525_3 Type IV Pilus-assembly protein W K02672 - - 0.000000000000000000000003593 115.0
HKD3_k127_1661525_4 Pilus assembly protein PilX - - - 0.0000000000000001336 93.0
HKD3_k127_1661525_5 Type II transport protein GspH K08084 - - 0.0000000000000281 84.0
HKD3_k127_1661525_6 type IV pilus modification protein PilV K02671 - - 0.00000000002517 75.0
HKD3_k127_1681172_0 transport system, permease component K05778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 531.0
HKD3_k127_1681172_1 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000008289 181.0
HKD3_k127_1682633_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 385.0
HKD3_k127_1682633_1 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 350.0
HKD3_k127_1682633_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 337.0
HKD3_k127_1682633_3 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 299.0
HKD3_k127_1682633_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000001044 235.0
HKD3_k127_1692958_0 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001979 282.0
HKD3_k127_1692958_1 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000008235 184.0
HKD3_k127_1692958_2 Met-10+ like-protein - - - 0.00000000000000000000168 102.0
HKD3_k127_1692958_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.0000000008801 60.0
HKD3_k127_1694188_0 GMC oxidoreductase - - - 1.359e-203 647.0
HKD3_k127_1694188_1 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 398.0
HKD3_k127_1694188_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 297.0
HKD3_k127_1694188_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001683 226.0
HKD3_k127_1694188_4 PFAM regulatory protein TetR - - - 0.000000000000000000000000000000000000000000000000000000001001 215.0
HKD3_k127_1694188_5 - - - - 0.000000000000000000000000000000000000000000001792 175.0
HKD3_k127_1694188_6 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000002444 141.0
HKD3_k127_1694188_7 twin-arginine translocation pathway signal protein - - - 0.000000000000000000000000000000001618 135.0
HKD3_k127_1694188_8 polyhydroxyalkanoic acid - - - 0.0000000001384 66.0
HKD3_k127_1694188_9 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00008576 51.0
HKD3_k127_1724549_0 Methyl-transferase K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 353.0
HKD3_k127_1724549_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002798 257.0
HKD3_k127_1724549_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000004777 207.0
HKD3_k127_172528_0 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 601.0
HKD3_k127_172528_1 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 388.0
HKD3_k127_172528_2 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000009889 130.0
HKD3_k127_1729315_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 291.0
HKD3_k127_1729315_1 Tripartite tricarboxylate transporter TctA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005553 254.0
HKD3_k127_1729315_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000002807 204.0
HKD3_k127_1729315_3 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000006131 116.0
HKD3_k127_1729315_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000006149 79.0
HKD3_k127_1763656_0 Histidine kinase - - - 0.000000000000001948 90.0
HKD3_k127_1773843_0 Sulfatase - - - 0.00000000000000000000000000000000000004064 146.0
HKD3_k127_1773843_2 - - - - 0.00000002877 61.0
HKD3_k127_1773843_3 Cupin - - - 0.0008989 42.0
HKD3_k127_17790_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 610.0
HKD3_k127_17790_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 580.0
HKD3_k127_17790_2 STAS domain K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 578.0
HKD3_k127_17790_3 taurine ABC transporter, periplasmic binding protein K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 413.0
HKD3_k127_17790_4 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 405.0
HKD3_k127_17790_5 Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system K10831 - 3.6.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 368.0
HKD3_k127_17790_6 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000001178 233.0
HKD3_k127_17790_7 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000001847 213.0
HKD3_k127_17790_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000004676 135.0
HKD3_k127_17790_9 Outer membrane lipoprotein K06077 - - 0.000000000000000000000000000002184 121.0
HKD3_k127_1780429_0 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 368.0
HKD3_k127_1780429_1 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 368.0
HKD3_k127_1780429_2 PFAM fumarylacetoacetate (FAA) hydrolase K01826 - 5.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 355.0
HKD3_k127_1780429_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 276.0
HKD3_k127_1780429_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000009491 231.0
HKD3_k127_1780429_5 - - - - 0.0000001274 64.0
HKD3_k127_1782470_0 Glycosyl transferases group 1 - - - 3.926e-212 678.0
HKD3_k127_1782470_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 471.0
HKD3_k127_1814016_0 GMC oxidoreductase K00108 - 1.1.99.1 4.879e-202 637.0
HKD3_k127_1814016_1 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004942 487.0
HKD3_k127_1816868_0 Pfam Enoyl-CoA hydratase isomerase K15513 - 4.1.2.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 434.0
HKD3_k127_1816868_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 414.0
HKD3_k127_1816868_2 Domain of unknown function (DUF4863) - - - 0.00000000000000000000000000000000000000000000000000000000000000001611 243.0
HKD3_k127_1816868_3 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.0000000000000000001231 93.0
HKD3_k127_1856227_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 475.0
HKD3_k127_1856227_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001495 238.0
HKD3_k127_1856227_2 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000002744 206.0
HKD3_k127_1856227_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000005773 203.0
HKD3_k127_1861472_0 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004834 262.0
HKD3_k127_1861472_1 YgbB family K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000001026 218.0
HKD3_k127_1861472_2 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000011 115.0
HKD3_k127_1877214_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.938e-225 707.0
HKD3_k127_1877214_1 Cys/Met metabolism PLP-dependent enzyme K01739,K01740 - 2.5.1.48,2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 571.0
HKD3_k127_1877214_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000003555 253.0
HKD3_k127_1877214_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000006944 228.0
HKD3_k127_1877214_4 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000001365 217.0
HKD3_k127_1877214_5 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000003499 132.0
HKD3_k127_1877214_6 Psort location CytoplasmicMembrane, score K03558 - - 0.00000000000000000000000001697 117.0
HKD3_k127_1877214_7 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.000000000008768 68.0
HKD3_k127_1881280_0 PFAM AIR synthase related protein domain protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 315.0
HKD3_k127_1881280_1 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 306.0
HKD3_k127_1881280_2 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000006602 187.0
HKD3_k127_1881280_3 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000004713 179.0
HKD3_k127_192230_0 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 309.0
HKD3_k127_192230_1 ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001819 265.0
HKD3_k127_192230_2 AzlC protein - - - 0.00000000000000000000000000000000000000000000001967 179.0
HKD3_k127_192230_3 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000008001 77.0
HKD3_k127_1946227_0 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 495.0
HKD3_k127_1946227_1 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 421.0
HKD3_k127_1946227_2 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 410.0
HKD3_k127_1946227_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 317.0
HKD3_k127_1946227_4 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005965 293.0
HKD3_k127_1946227_5 HAF family - - - 0.000000000000000000000000000003861 135.0
HKD3_k127_195232_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 541.0
HKD3_k127_195232_1 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003215 278.0
HKD3_k127_195232_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000001747 192.0
HKD3_k127_195232_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000002767 162.0
HKD3_k127_195232_4 acetyltransferase - - - 0.0000000000000000000000000000000000004263 146.0
HKD3_k127_196108_0 NADH-quinone oxidoreductase K00336 - 1.6.5.3 1.404e-298 936.0
HKD3_k127_196108_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 503.0
HKD3_k127_196108_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000005554 139.0
HKD3_k127_196108_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000004895 61.0
HKD3_k127_1968542_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 4.396e-197 628.0
HKD3_k127_1968542_1 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 370.0
HKD3_k127_1968542_2 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002956 285.0
HKD3_k127_1968542_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001344 274.0
HKD3_k127_1968542_4 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 0.0000000000009565 69.0
HKD3_k127_1968542_5 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000009907 68.0
HKD3_k127_1968542_6 Glycine zipper 2TM domain - - - 0.0003516 49.0
HKD3_k127_1984356_0 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 369.0
HKD3_k127_1984356_1 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 362.0
HKD3_k127_1984356_2 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 305.0
HKD3_k127_1984356_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000003713 151.0
HKD3_k127_1984356_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000003901 72.0
HKD3_k127_200996_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1328.0
HKD3_k127_200996_1 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 2.372e-250 806.0
HKD3_k127_200996_10 LysE type translocator K05834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001327 244.0
HKD3_k127_200996_11 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000005266 233.0
HKD3_k127_200996_12 Hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000003009 175.0
HKD3_k127_200996_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000002538 168.0
HKD3_k127_200996_14 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000001703 118.0
HKD3_k127_200996_15 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00003203 56.0
HKD3_k127_200996_2 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 5.987e-232 763.0
HKD3_k127_200996_3 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 1.109e-212 679.0
HKD3_k127_200996_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 651.0
HKD3_k127_200996_5 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 365.0
HKD3_k127_200996_6 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 332.0
HKD3_k127_200996_7 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 316.0
HKD3_k127_200996_8 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
HKD3_k127_200996_9 PFAM FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004539 255.0
HKD3_k127_205430_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.413e-292 942.0
HKD3_k127_205430_1 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 483.0
HKD3_k127_205430_2 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000004499 225.0
HKD3_k127_205430_3 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000005324 217.0
HKD3_k127_2066336_0 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons - - - 7.345e-219 712.0
HKD3_k127_2066336_1 PFAM acyl-CoA dehydrogenase domain protein K00249,K07545 - 1.3.8.3,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 560.0
HKD3_k127_2066336_2 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009927 448.0
HKD3_k127_2066336_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 399.0
HKD3_k127_2066336_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 341.0
HKD3_k127_2066336_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 310.0
HKD3_k127_2066336_6 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000005692 262.0
HKD3_k127_2066336_7 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009917 246.0
HKD3_k127_2066336_8 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000000000000000000000000000000000000000000001681 194.0
HKD3_k127_2066336_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000001322 166.0
HKD3_k127_2077934_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 538.0
HKD3_k127_2077934_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000006656 241.0
HKD3_k127_2077934_2 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000002534 230.0
HKD3_k127_2077934_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000001058 63.0
HKD3_k127_208574_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 476.0
HKD3_k127_208574_1 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006084,GO:0006139,GO:0006163,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009117,GO:0009150,GO:0009259,GO:0009308,GO:0009310,GO:0009987,GO:0016043,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0019439,GO:0019441,GO:0019442,GO:0019637,GO:0019693,GO:0019752,GO:0020037,GO:0022607,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046906,GO:0048037,GO:0051186,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.13.11.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 386.0
HKD3_k127_208574_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007221 336.0
HKD3_k127_208574_3 abc transporter atp-binding protein K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 309.0
HKD3_k127_208574_4 sodium ABC transporter, permease K09696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003227 265.0
HKD3_k127_208574_5 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000227 180.0
HKD3_k127_208574_6 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000001726 187.0
HKD3_k127_210382_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.234e-317 983.0
HKD3_k127_210382_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 468.0
HKD3_k127_210382_2 amino acid K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 456.0
HKD3_k127_210382_3 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 460.0
HKD3_k127_210382_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 355.0
HKD3_k127_210382_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008486 275.0
HKD3_k127_210382_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002124 254.0
HKD3_k127_210382_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000009333 157.0
HKD3_k127_2168724_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 454.0
HKD3_k127_2168724_1 short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 407.0
HKD3_k127_2168724_2 amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 345.0
HKD3_k127_2168724_3 Eukaryotic DNA topoisomerase I, catalytic core K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 319.0
HKD3_k127_2168724_4 Transglycosylase associated protein - - - 0.00000000000000000000000000001247 130.0
HKD3_k127_2185677_0 ABC transporter K06020 - 3.6.3.25 3.411e-295 912.0
HKD3_k127_2185677_1 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000241 240.0
HKD3_k127_2185677_2 domain, Protein K19615 - - 0.000000000000000000000000000000000007721 157.0
HKD3_k127_2185677_3 - - - - 0.00000000000000000000000009171 113.0
HKD3_k127_2185677_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000001999 111.0
HKD3_k127_2185677_5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000005234 63.0
HKD3_k127_2185677_6 - - - - 0.00001726 51.0
HKD3_k127_2198147_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 484.0
HKD3_k127_2198147_1 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002086 276.0
HKD3_k127_2198147_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002994 232.0
HKD3_k127_2198147_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000003138 237.0
HKD3_k127_2198147_4 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.00000000000000000000000000001317 122.0
HKD3_k127_220816_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 2.574e-194 617.0
HKD3_k127_2212517_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 318.0
HKD3_k127_2212517_1 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000009008 210.0
HKD3_k127_2212517_2 SdpI/YhfL protein family - - - 0.00000000000001159 78.0
HKD3_k127_2212517_3 Helix-turn-helix domain - - - 0.0005426 49.0
HKD3_k127_2215085_0 Pfam:DUF59 - - - 0.00000000000000000000000000000000000000000000000000003631 194.0
HKD3_k127_2215085_1 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000002171 134.0
HKD3_k127_2215085_3 Arm DNA-binding domain K14059 - - 0.00000000001195 70.0
HKD3_k127_2282045_0 PfkB domain protein K03338 - 2.7.1.92 5.648e-287 896.0
HKD3_k127_2282045_1 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 542.0
HKD3_k127_2282045_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004733 374.0
HKD3_k127_2282045_3 Belongs to the TPP enzyme family K03336 - 3.7.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 355.0
HKD3_k127_2282045_4 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000002128 156.0
HKD3_k127_231114_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.876e-277 873.0
HKD3_k127_231114_1 AMP-binding enzyme C-terminal domain K00666,K20034 - 6.2.1.44 2.899e-247 774.0
HKD3_k127_231114_10 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000001462 151.0
HKD3_k127_231114_11 PFAM PsiF repeat protein - - - 0.00000000000000006056 88.0
HKD3_k127_231114_12 Acetyltransferase (GNAT) domain - - - 0.000004184 54.0
HKD3_k127_231114_2 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 4.697e-204 644.0
HKD3_k127_231114_3 DAHP synthetase I family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 594.0
HKD3_k127_231114_4 PFAM alpha beta hydrolase K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 376.0
HKD3_k127_231114_5 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 347.0
HKD3_k127_231114_6 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 298.0
HKD3_k127_231114_7 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002276 276.0
HKD3_k127_231114_8 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001147 252.0
HKD3_k127_231114_9 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
HKD3_k127_2413293_0 Dynamin family - - - 1.873e-224 715.0
HKD3_k127_2413293_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 567.0
HKD3_k127_2413293_10 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003429 282.0
HKD3_k127_2413293_11 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001514 251.0
HKD3_k127_2413293_12 Peptidyl-tRNA hydrolase K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000002274 232.0
HKD3_k127_2413293_13 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000255 212.0
HKD3_k127_2413293_14 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000002012 148.0
HKD3_k127_2413293_15 Outer membrane lipoprotein LolB - - - 0.00000000000000000000000000003464 127.0
HKD3_k127_2413293_16 Cna B domain protein - - - 0.0000000000005594 82.0
HKD3_k127_2413293_17 Late embryogenesis abundant protein - - - 0.00002729 53.0
HKD3_k127_2413293_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 502.0
HKD3_k127_2413293_3 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 416.0
HKD3_k127_2413293_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 381.0
HKD3_k127_2413293_5 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 376.0
HKD3_k127_2413293_6 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 307.0
HKD3_k127_2413293_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 319.0
HKD3_k127_2413293_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001123 284.0
HKD3_k127_2413293_9 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002683 286.0
HKD3_k127_2416341_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003703 250.0
HKD3_k127_2416341_1 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000007335 228.0
HKD3_k127_2416341_2 Coenzyme A transferase K01026 - 2.8.3.1 0.00000000000000000000000003826 109.0
HKD3_k127_2416341_3 PFAM OmpA MotB domain protein - - - 0.00000000000000000000000005248 113.0
HKD3_k127_2420789_0 Methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009338 460.0
HKD3_k127_2420789_1 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 290.0
HKD3_k127_2420789_2 Alpha beta hydrolase K01066 - - 0.0000000000000000000000000000000000000000616 160.0
HKD3_k127_2436707_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 396.0
HKD3_k127_2436707_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 368.0
HKD3_k127_2436707_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 366.0
HKD3_k127_2436707_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000001817 233.0
HKD3_k127_2436707_4 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000002209 156.0
HKD3_k127_2449091_0 peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000007267 199.0
HKD3_k127_2449091_1 PFAM plasmid K06218 - - 0.00000000000000000000000000159 116.0
HKD3_k127_2449091_2 PIN domain - - - 0.00001271 48.0
HKD3_k127_2455221_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1542.0
HKD3_k127_2455221_1 RNA secondary structure unwinding K03724 - - 8.429e-305 961.0
HKD3_k127_2455221_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 599.0
HKD3_k127_2455221_3 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 551.0
HKD3_k127_2455221_4 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000006167 233.0
HKD3_k127_2455221_5 CHRD domain - - - 0.00000000000000000000000000000000000000001367 164.0
HKD3_k127_2455221_6 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000127 96.0
HKD3_k127_2455221_7 - - - - 0.0000000000007743 72.0
HKD3_k127_2455221_8 SdpI/YhfL protein family - - - 0.00000001202 59.0
HKD3_k127_2455353_0 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 415.0
HKD3_k127_2455353_1 Catalyzes the sodium-dependent transport of glutamate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 374.0
HKD3_k127_2455353_10 Putative stress-induced transcription regulator - - - 0.000000000000000000001092 103.0
HKD3_k127_2455353_11 LytTr DNA-binding domain K02477 - - 0.000000000000000000003223 101.0
HKD3_k127_2455353_12 LytTr DNA-binding domain K02477 - - 0.000000000000000001785 91.0
HKD3_k127_2455353_13 TonB dependent receptor K02014 - - 0.00000002989 65.0
HKD3_k127_2455353_14 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000008402 58.0
HKD3_k127_2455353_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 316.0
HKD3_k127_2455353_3 Dihydrodipicolinate synthetase family K13876 - 4.2.1.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 301.0
HKD3_k127_2455353_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005755 292.0
HKD3_k127_2455353_5 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000002521 239.0
HKD3_k127_2455353_6 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000001606 228.0
HKD3_k127_2455353_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000007371 163.0
HKD3_k127_2455353_8 Belongs to the IlvD Edd family K13875 - 4.2.1.25 0.000000000000000000000000000005807 120.0
HKD3_k127_2455353_9 - - - - 0.00000000000000000000000000001947 121.0
HKD3_k127_24562_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 480.0
HKD3_k127_24562_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 409.0
HKD3_k127_24562_2 DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001585 289.0
HKD3_k127_24562_3 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.0000000000000000000000000000000000000000000000000000000004036 203.0
HKD3_k127_24562_4 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000008403 151.0
HKD3_k127_24562_5 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.0000001608 57.0
HKD3_k127_2460100_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.879e-302 949.0
HKD3_k127_2460438_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.114e-206 649.0
HKD3_k127_2460438_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 2.551e-194 620.0
HKD3_k127_2460438_2 pilus assembly protein tip-associated adhesin K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 459.0
HKD3_k127_2460438_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 400.0
HKD3_k127_2460438_4 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000003141 248.0
HKD3_k127_2460438_5 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
HKD3_k127_2460438_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000003779 239.0
HKD3_k127_2460438_7 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000165 103.0
HKD3_k127_2463905_0 binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 620.0
HKD3_k127_2463905_1 Aldehyde dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 605.0
HKD3_k127_2463905_2 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 566.0
HKD3_k127_2463905_3 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 476.0
HKD3_k127_2463905_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007167 379.0
HKD3_k127_2463905_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003632 275.0
HKD3_k127_2463905_6 Thioesterase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000001883 195.0
HKD3_k127_2463905_7 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000007448 200.0
HKD3_k127_2464450_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000499 272.0
HKD3_k127_2464450_1 ChrR Cupin-like domain K05913 - 1.13.11.41 0.00000000000000000000000000000000000000000000000000000002763 203.0
HKD3_k127_2464450_2 transcriptional regulator - - - 0.000000000000000000000144 110.0
HKD3_k127_2473971_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 2.195e-227 712.0
HKD3_k127_2473971_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001547 284.0
HKD3_k127_2473971_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000005843 271.0
HKD3_k127_2473971_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000238 161.0
HKD3_k127_2473971_4 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000001083 169.0
HKD3_k127_2491107_0 TIGRFAM 3-oxoacid CoA-transferase, B subunit K01032 - 2.8.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 334.0
HKD3_k127_2491107_1 very-long-chain-acyl-CoA dehydrogenase activity K17880,K18817 - 2.7.1.119,2.7.1.163 0.00000000000000000000000000000000000000000000000000000000000000000000002001 258.0
HKD3_k127_2491107_2 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000002991 241.0
HKD3_k127_2491107_3 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000003022 160.0
HKD3_k127_2491107_4 RNA cap guanine-N2 methyltransferase - - - 0.0000000000000000000000000000001128 141.0
HKD3_k127_2491107_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000005407 124.0
HKD3_k127_2491107_6 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01031 - 2.8.3.6 0.00000000000000000000003226 100.0
HKD3_k127_2491107_7 phosphatase activity - - - 0.0000001973 57.0
HKD3_k127_2491107_8 Protein of unknown function (DUF2628) - - - 0.0000002772 62.0
HKD3_k127_2491794_0 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 414.0
HKD3_k127_2491794_1 Transcriptional regulatory protein, C terminal K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 313.0
HKD3_k127_2491794_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 278.0
HKD3_k127_2491794_3 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008045 260.0
HKD3_k127_2491794_4 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000005838 212.0
HKD3_k127_2491794_5 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000006692 212.0
HKD3_k127_2508043_0 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 529.0
HKD3_k127_2508043_1 peptidase dimerisation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 532.0
HKD3_k127_2508043_2 N-terminal TM domain of oligopeptide transport permease C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 453.0
HKD3_k127_2508043_3 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 377.0
HKD3_k127_2508043_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000002064 209.0
HKD3_k127_2508043_5 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000001386 92.0
HKD3_k127_2510663_0 Soluble lytic murein transglycosylase L domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 332.0
HKD3_k127_2510663_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000001004 57.0
HKD3_k127_251335_0 oxidoreductase activity - - - 6.205e-315 973.0
HKD3_k127_251335_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 486.0
HKD3_k127_251335_2 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 421.0
HKD3_k127_251335_3 PFAM response regulator receiver K11443 - - 0.000000000000000000000000000000000004824 153.0
HKD3_k127_251335_4 - - - - 0.000006701 58.0
HKD3_k127_251478_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1519.0
HKD3_k127_251478_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000009927 67.0
HKD3_k127_251478_2 PFAM ATP-binding region, ATPase domain protein - - - 0.000000001451 66.0
HKD3_k127_25214_0 Belongs to the UPF0061 (SELO) family - - - 1.21e-239 751.0
HKD3_k127_25214_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 452.0
HKD3_k127_25214_2 ABC transporter transmembrane region K11085 - - 0.0000000000000000000000000000000000000001117 156.0
HKD3_k127_25214_3 Double zinc ribbon - - - 0.00000000000007166 81.0
HKD3_k127_25214_4 nitrite sulfite reductase hemoprotein beta-component ferrodoxin domain protein K00381,K00392 - 1.8.1.2,1.8.7.1 0.00000003555 61.0
HKD3_k127_2525617_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 5.329e-229 728.0
HKD3_k127_2525617_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 572.0
HKD3_k127_2525617_2 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000002263 168.0
HKD3_k127_2525617_3 - - - - 0.0000000008015 68.0
HKD3_k127_2525617_4 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K02488 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65 0.00000003072 64.0
HKD3_k127_2526044_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000006125 183.0
HKD3_k127_2526044_1 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.00000000000000000000000001702 123.0
HKD3_k127_2540771_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 597.0
HKD3_k127_2551839_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 5.087e-249 781.0
HKD3_k127_2551839_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 360.0
HKD3_k127_2552048_0 Cation transporter/ATPase, N-terminus K01531,K01535 - 3.6.3.2,3.6.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 396.0
HKD3_k127_2552048_1 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001055 263.0
HKD3_k127_2552048_2 Helix-turn-helix K21498 - - 0.00000000000000000000000006032 111.0
HKD3_k127_2552048_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000001271 73.0
HKD3_k127_255602_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 5.983e-320 1004.0
HKD3_k127_255602_1 Fumarase C C-terminus K01744 - 4.3.1.1 3.277e-268 831.0
HKD3_k127_255602_10 fumarate reductase K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 321.0
HKD3_k127_255602_11 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003889 243.0
HKD3_k127_255602_12 PFAM Extracellular solute-binding protein, family 3 K10001 - - 0.000000000000000000000000000000000000000000000000000001632 205.0
HKD3_k127_255602_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000002828 111.0
HKD3_k127_255602_14 Tautomerase enzyme K01821 - 5.3.2.6 0.000000000000004102 78.0
HKD3_k127_255602_2 Responsible for the transport of C4-dicarboxylates from the periplasm across the inner membrane K07791,K07792 - - 1.517e-239 746.0
HKD3_k127_255602_3 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 6.696e-228 715.0
HKD3_k127_255602_4 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.197e-220 688.0
HKD3_k127_255602_5 Arsenical pump membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 564.0
HKD3_k127_255602_6 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 514.0
HKD3_k127_255602_7 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 447.0
HKD3_k127_255602_8 TIGRFAM Succinate dehydrogenase fumarate reductase iron-sulphur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 376.0
HKD3_k127_255602_9 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 336.0
HKD3_k127_2575045_0 modulator of DNA gyrase K03568 - - 2.291e-220 693.0
HKD3_k127_2575045_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 610.0
HKD3_k127_2575045_2 KaiC K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 533.0
HKD3_k127_2575045_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008474 456.0
HKD3_k127_2575045_4 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 335.0
HKD3_k127_2575045_5 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 304.0
HKD3_k127_2575045_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006532,GO:0006551,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009098,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.000000000000000000000000000000000007434 137.0
HKD3_k127_2575045_7 SnoaL-like domain - - - 0.0000000000000000000000000002217 119.0
HKD3_k127_2575045_8 Zinc-finger domain - - - 0.0000000000000000004961 87.0
HKD3_k127_257732_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 323.0
HKD3_k127_257732_1 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000001532 237.0
HKD3_k127_257732_2 Subtilase family K14645 - - 0.0000000000002115 83.0
HKD3_k127_257732_3 bacterial-type flagellum-dependent cell motility K21449 - - 0.000000000001965 80.0
HKD3_k127_2583575_0 UTRA domain K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 346.0
HKD3_k127_2583575_1 Dehydratase family K22186 - 4.2.1.82 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 328.0
HKD3_k127_2583575_2 SAF K16845 - 4.4.1.24 0.000003196 50.0
HKD3_k127_2586684_0 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 561.0
HKD3_k127_2586684_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 422.0
HKD3_k127_2586684_2 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 358.0
HKD3_k127_2586684_3 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000005431 204.0
HKD3_k127_2586684_4 FCD - - - 0.0000000000000000000000000000000000000000000000000001528 198.0
HKD3_k127_2586684_5 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000002303 168.0
HKD3_k127_2586684_6 Tripartite ATP-independent periplasmic transporter, DctQ - - - 0.0000000000000000000000000000000000000003238 155.0
HKD3_k127_2586684_7 - - - - 0.0000000000000000000000006793 120.0
HKD3_k127_2586684_8 2-methylisocitrate dehydratase, Fe S-dependent K20455 - 4.2.1.117 0.000000000008148 64.0
HKD3_k127_2587713_0 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000116 224.0
HKD3_k127_2587713_1 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000006288 111.0
HKD3_k127_2587713_2 RDD family - - - 0.0000000000001359 82.0
HKD3_k127_2589460_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 486.0
HKD3_k127_2589460_1 Belongs to the malate synthase family K01638 - 2.3.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 406.0
HKD3_k127_2589460_2 ATPases associated with a variety of cellular activities K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 398.0
HKD3_k127_2589460_3 COG4149 ABC-type molybdate transport system, permease component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 311.0
HKD3_k127_2589460_4 Molybdenum ABC transporter periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 297.0
HKD3_k127_2589460_5 transcriptional regulator - - - 0.000000000000000000000000000000000000001463 161.0
HKD3_k127_2589460_6 Transcriptional regulator, ModE family K02019 - - 0.0000000000000000002549 94.0
HKD3_k127_2598234_0 Phospholipase_D-nuclease N-terminal K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 525.0
HKD3_k127_2598234_1 Arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 402.0
HKD3_k127_2598234_2 - - - - 0.0007333 52.0
HKD3_k127_2600514_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 586.0
HKD3_k127_2600514_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 543.0
HKD3_k127_2600514_2 Transporter K11688,K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 528.0
HKD3_k127_2600514_3 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 539.0
HKD3_k127_2600514_4 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 413.0
HKD3_k127_2600514_5 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000112 241.0
HKD3_k127_2600514_6 Tripartite ATP-independent periplasmic transporter - - - 0.000000000000000000000000000000000000000000000000000005666 196.0
HKD3_k127_2605078_0 AMP-binding enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 497.0
HKD3_k127_2605078_1 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002657 285.0
HKD3_k127_2605078_2 Thermostable hemolysin - - - 0.000000000000000000000000000000000000000000001821 176.0
HKD3_k127_2605078_3 Iron-containing redox enzyme - - - 0.000000000000000000000000000000000000000006066 177.0
HKD3_k127_2611906_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000664 557.0
HKD3_k127_2611906_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 544.0
HKD3_k127_2611906_10 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000003852 214.0
HKD3_k127_2611906_11 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000001001 209.0
HKD3_k127_2611906_12 membrane - - - 0.0000000000000000000000000000000000000000000000003722 180.0
HKD3_k127_2611906_13 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000004194 169.0
HKD3_k127_2611906_14 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000005578 123.0
HKD3_k127_2611906_15 Glyco_18 K01183 - 3.2.1.14 0.0000000000000000003784 103.0
HKD3_k127_2611906_16 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000005218 58.0
HKD3_k127_2611906_17 polysaccharide catabolic process K02388,K02396 - - 0.0002887 54.0
HKD3_k127_2611906_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 421.0
HKD3_k127_2611906_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 289.0
HKD3_k127_2611906_4 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 285.0
HKD3_k127_2611906_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006756 275.0
HKD3_k127_2611906_6 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002417 276.0
HKD3_k127_2611906_7 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000002254 264.0
HKD3_k127_2611906_8 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000003591 278.0
HKD3_k127_2611906_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002066 264.0
HKD3_k127_261437_0 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 436.0
HKD3_k127_261437_1 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000001281 59.0
HKD3_k127_261437_2 Plasmid maintenance system killer K07334 - - 0.0000000325 59.0
HKD3_k127_2618627_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 389.0
HKD3_k127_2618627_1 drug resistance transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 390.0
HKD3_k127_2618627_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 372.0
HKD3_k127_2618627_3 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 338.0
HKD3_k127_2618627_4 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000006872 243.0
HKD3_k127_2618627_5 Bacterial regulatory helix-turn-helix protein, lysR family K13634 - - 0.0000000000000000000000000000000000000000000000000007844 186.0
HKD3_k127_2618627_6 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000209 151.0
HKD3_k127_2618627_7 rieske 2fe-2s - - - 0.0000000000000000000000000008735 124.0
HKD3_k127_2625437_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 2.025e-198 625.0
HKD3_k127_2625437_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 303.0
HKD3_k127_2625437_2 Ankyrin repeats (many copies) K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009411 252.0
HKD3_k127_2625437_3 - - - - 0.0000000000000000000000000000000000000004792 156.0
HKD3_k127_2625437_4 NADH:flavin oxidoreductase / NADH oxidase family K00354 - 1.6.99.1 0.0000000000000000000000000000000000000006625 150.0
HKD3_k127_2625437_5 - - - - 0.000000000003767 68.0
HKD3_k127_2639712_0 von Willebrand factor type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001074 287.0
HKD3_k127_2639712_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001684 237.0
HKD3_k127_2640525_0 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1321.0
HKD3_k127_2640525_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 441.0
HKD3_k127_2640525_10 - - - - 0.000000000000000000009888 96.0
HKD3_k127_2640525_11 Tfp pilus assembly protein FimV - - - 0.0000000000004739 79.0
HKD3_k127_2640525_2 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 385.0
HKD3_k127_2640525_3 PFAM NAD-dependent epimerase dehydratase K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 355.0
HKD3_k127_2640525_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 320.0
HKD3_k127_2640525_5 Glutathione S-transferase, N-terminal domain K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001713 243.0
HKD3_k127_2640525_6 spore germination - GO:0000099,GO:0000101,GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015318,GO:0015711,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072348,GO:0098656,GO:1901682,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000002828 211.0
HKD3_k127_2640525_7 stringent starvation protein B K03600 - - 0.0000000000000000000000000000000006658 139.0
HKD3_k127_2640525_8 Major Facilitator Superfamily - - - 0.000000000000000000000000134 120.0
HKD3_k127_2640525_9 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000003371 108.0
HKD3_k127_2646650_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 611.0
HKD3_k127_2646650_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 493.0
HKD3_k127_2646650_2 Protein of unknown function (DUF3095) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 390.0
HKD3_k127_2646650_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000007354 239.0
HKD3_k127_2646650_4 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000002541 223.0
HKD3_k127_2646650_5 Belongs to the P-Pant transferase superfamily K06133 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008897,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.000000000000000000002756 104.0
HKD3_k127_2650517_0 amino acid transport system, periplasmic component K01999 - - 8.915e-195 617.0
HKD3_k127_2650517_1 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 568.0
HKD3_k127_2650517_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 535.0
HKD3_k127_2650517_3 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 494.0
HKD3_k127_2650517_4 branched-chain amino acid K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 434.0
HKD3_k127_2650517_5 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004984 288.0
HKD3_k127_2650517_6 polysaccharide deacetylase - - - 0.000000000000000000000000000000000303 151.0
HKD3_k127_2650517_7 YjbR - - - 0.0000000000000000000000001107 111.0
HKD3_k127_2667487_0 Neisseria PilC beta-propeller domain K02674 - - 6.073e-236 759.0
HKD3_k127_2667487_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 331.0
HKD3_k127_2667487_10 - - - - 0.00000006323 64.0
HKD3_k127_2667487_2 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001489 267.0
HKD3_k127_2667487_3 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000283 179.0
HKD3_k127_2667487_4 TYPE 4 fimbrial BIOGENESIS K02672 - - 0.00000000000000000000000000000000000000000402 175.0
HKD3_k127_2667487_5 type IV pilus assembly protein PilV K02671 - - 0.00000000000000000000000001384 123.0
HKD3_k127_2667487_7 PilX N-terminal - - - 0.000000000000000008524 98.0
HKD3_k127_2667487_8 COG4968 Tfp pilus assembly protein PilE K02655 - - 0.000000000000009219 80.0
HKD3_k127_2667487_9 protein transport across the cell outer membrane K08084 - - 0.00000000001675 75.0
HKD3_k127_2671161_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 5.781e-209 656.0
HKD3_k127_2671161_1 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 419.0
HKD3_k127_2671161_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000002456 101.0
HKD3_k127_2671161_11 - - - - 0.0000000000000000000003424 104.0
HKD3_k127_2671161_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 331.0
HKD3_k127_2671161_3 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 286.0
HKD3_k127_2671161_4 PFAM Cytochrome C1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000007815 254.0
HKD3_k127_2671161_5 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000006549 186.0
HKD3_k127_2671161_6 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000000000000000001756 171.0
HKD3_k127_2671161_7 Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000001016 183.0
HKD3_k127_2671161_8 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000002291 136.0
HKD3_k127_2671161_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000004652 130.0
HKD3_k127_2714373_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 559.0
HKD3_k127_2714373_1 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 290.0
HKD3_k127_2714373_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000003516 123.0
HKD3_k127_2714826_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 7.698e-302 966.0
HKD3_k127_2714826_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 599.0
HKD3_k127_2714826_2 Belongs to the GPI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 467.0
HKD3_k127_2714826_3 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 446.0
HKD3_k127_2714826_4 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 432.0
HKD3_k127_2714826_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 361.0
HKD3_k127_2714826_6 COG2951 Membrane-bound lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001118 278.0
HKD3_k127_2714826_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000001284 202.0
HKD3_k127_2714826_8 MaoC like domain - - - 0.00000000000000000000000000000000000000008544 161.0
HKD3_k127_2714826_9 molybdopterin binding domain - - - 0.0000000000000000000000004881 108.0
HKD3_k127_2733038_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
HKD3_k127_2733038_1 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 380.0
HKD3_k127_2733038_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 350.0
HKD3_k127_2733038_3 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008393 254.0
HKD3_k127_2733038_4 - K11477 - - 0.000000000000000000000000000001275 132.0
HKD3_k127_2737694_0 Flavin containing amine oxidoreductase - - - 2.268e-246 770.0
HKD3_k127_2737694_1 Flavin containing amine oxidoreductase K09845 - 1.3.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002881 599.0
HKD3_k127_2737694_10 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000816 365.0
HKD3_k127_2737694_11 PFAM hydroxyneurosporene synthase K09844 - 4.2.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 367.0
HKD3_k127_2737694_12 Nitrogenase component 1 type Oxidoreductase K11334 - 1.3.7.14,1.3.7.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 342.0
HKD3_k127_2737694_13 carboxylic ester hydrolase activity K06049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 291.0
HKD3_k127_2737694_14 membrane - - - 0.0000000000000000000000000000000000002474 147.0
HKD3_k127_2737694_15 Heme oxygenase K21480 - 1.14.15.20 0.0000000000000000000000000000002596 141.0
HKD3_k127_2737694_16 Alpha/beta hydrolase family - - - 0.00000000000000000001725 102.0
HKD3_k127_2737694_17 Peptidoglycan-binding domain 1 protein K07273 - - 0.00000000236 69.0
HKD3_k127_2737694_2 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 582.0
HKD3_k127_2737694_3 Belongs to the NifH BchL ChlL family K11333 - 1.3.7.14,1.3.7.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 565.0
HKD3_k127_2737694_4 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 561.0
HKD3_k127_2737694_5 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 524.0
HKD3_k127_2737694_6 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 457.0
HKD3_k127_2737694_7 Dehydrogenase K11337 - 1.1.1.396 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006198 450.0
HKD3_k127_2737694_8 Dimerisation domain K09846 - 2.1.1.210 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 409.0
HKD3_k127_2737694_9 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 368.0
HKD3_k127_274762_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 370.0
HKD3_k127_274762_1 FtsJ-like methyltransferase K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000264 250.0
HKD3_k127_274762_2 - - - - 0.000000000000000001608 91.0
HKD3_k127_2778168_0 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000001404 104.0
HKD3_k127_2817283_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 468.0
HKD3_k127_2817283_1 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000000000000000000000000000000000002098 168.0
HKD3_k127_2817283_2 cyclic-guanylate-specific phosphodiesterase activity K13924,K21023 - 2.1.1.80,2.7.7.65,3.1.1.61 0.00000001164 57.0
HKD3_k127_2823873_0 B12 binding domain K04034 - 1.21.98.3 6.102e-286 886.0
HKD3_k127_2823873_1 AMP-binding enzyme C-terminal domain K00666 - - 1.378e-206 659.0
HKD3_k127_2823873_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000003727 260.0
HKD3_k127_2823873_11 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003909 262.0
HKD3_k127_2823873_12 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001328 277.0
HKD3_k127_2823873_13 SmpB protein K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000003573 233.0
HKD3_k127_2823873_14 DNA polymerase III, delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000001708 221.0
HKD3_k127_2823873_15 Cyclase dehydrase - - - 0.0000000000000000000000000000000000000000000000000001115 192.0
HKD3_k127_2823873_16 PFAM Type IV pilus assembly PilZ K02676 - - 0.00000000000000000000000000000000000000000004092 164.0
HKD3_k127_2823873_17 Ankyrin repeat K06867 - - 0.00000000000000000000000000000000000000000165 166.0
HKD3_k127_2823873_18 NLP P60 protein - - - 0.000000000000000000000000000000000000000001664 174.0
HKD3_k127_2823873_19 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000006841 75.0
HKD3_k127_2823873_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 1.197e-194 613.0
HKD3_k127_2823873_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 448.0
HKD3_k127_2823873_4 Squalene synthase HpnD K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 379.0
HKD3_k127_2823873_5 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008267 365.0
HKD3_k127_2823873_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 346.0
HKD3_k127_2823873_7 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 324.0
HKD3_k127_2823873_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 322.0
HKD3_k127_2823873_9 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 319.0
HKD3_k127_2836255_0 Methionine synthase K00548 - 2.1.1.13 2.946e-247 777.0
HKD3_k127_2836255_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 558.0
HKD3_k127_2836255_10 Trypsin-like peptidase domain - - - 0.00005313 55.0
HKD3_k127_2836255_2 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 476.0
HKD3_k127_2836255_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 437.0
HKD3_k127_2836255_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007435 263.0
HKD3_k127_2836255_5 Tryptophan-rich sensory protein K05770 - - 0.0000000000000000000000000000000000000000000000000005451 209.0
HKD3_k127_2836255_6 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000009305 155.0
HKD3_k127_2836255_7 ChrR Cupin-like domain - - - 0.00000000000000000000000000001433 122.0
HKD3_k127_2836255_8 DKNYY family - - - 0.0000000000000000000000000001256 126.0
HKD3_k127_2836255_9 Thioredoxin - - - 0.00000000000000000000243 102.0
HKD3_k127_2846625_0 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 520.0
HKD3_k127_2846625_1 Cobalamin-independent synthase, Catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 515.0
HKD3_k127_2846625_2 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 398.0
HKD3_k127_2846625_3 Bacterial extracellular solute-binding protein K02027 - - 0.000000000000000000001171 97.0
HKD3_k127_2846625_4 Cold shock protein K03704 - - 0.0000000000000000007464 85.0
HKD3_k127_2853843_0 domain, Protein K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002029 299.0
HKD3_k127_2853843_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000002082 210.0
HKD3_k127_2853843_2 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287,K18589 - 1.5.1.3 0.000000000000000000000000000000000000000000000000006983 186.0
HKD3_k127_2864728_0 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 297.0
HKD3_k127_2864728_1 ABC transporter, ATP-binding protein K06020 - 3.6.3.25 0.0000000000000000000000000000000000000000001424 160.0
HKD3_k127_2864728_2 Psort location Cytoplasmic, score 9.97 K01142 - 3.1.11.2 0.00000000000000000000000000000000000002637 150.0
HKD3_k127_2864728_3 Domain of unknown function (DUF4124) - - - 0.0000000000003038 82.0
HKD3_k127_2871346_0 Protein of unknown function (DUF3141) - - - 0.0 1030.0
HKD3_k127_2871346_1 phosphate K00625 - 2.3.1.8 0.0000000000000000000000000000000002254 134.0
HKD3_k127_2871346_2 Protein of unknown function (DUF3300) - - - 0.00000000000000000000002994 103.0
HKD3_k127_2882398_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 2.241e-292 925.0
HKD3_k127_2882398_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 584.0
HKD3_k127_2882398_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 432.0
HKD3_k127_2882398_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 370.0
HKD3_k127_2882398_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000006295 224.0
HKD3_k127_2882398_5 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000008761 149.0
HKD3_k127_2883372_0 PFAM Coenzyme A transferase K01026 - 2.8.3.1 6.046e-217 694.0
HKD3_k127_2883372_1 PFAM Methionine synthase vitamin-B12 independent K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 488.0
HKD3_k127_2883372_2 Lanthionine synthetase C-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 368.0
HKD3_k127_2883372_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004658 237.0
HKD3_k127_2883372_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000003398 232.0
HKD3_k127_2883372_5 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000001473 222.0
HKD3_k127_2883372_6 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000001062 161.0
HKD3_k127_2883372_7 Hemerythrin HHE cation binding - - - 0.000000000000000000000000000000000000001438 153.0
HKD3_k127_2888273_0 carbohydrate binding - - - 0.0 1372.0
HKD3_k127_291478_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 575.0
HKD3_k127_291478_1 Helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 376.0
HKD3_k127_291478_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 364.0
HKD3_k127_291478_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 314.0
HKD3_k127_291478_4 ZIP Zinc transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007496 245.0
HKD3_k127_291478_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000757 217.0
HKD3_k127_291478_6 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.00000000000000000000000000000000000000000000000000000008012 199.0
HKD3_k127_2926610_0 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 536.0
HKD3_k127_2926610_1 Belongs to the aldehyde dehydrogenase family K00154,K22445 - 1.2.1.68,1.2.99.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 541.0
HKD3_k127_2926610_2 AlkA N-terminal domain K13529,K13530 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 537.0
HKD3_k127_2926610_3 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008764 359.0
HKD3_k127_2926610_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002227 255.0
HKD3_k127_2926610_5 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000007839 237.0
HKD3_k127_2926610_6 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000001094 168.0
HKD3_k127_2926610_7 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000004684 57.0
HKD3_k127_2926754_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 480.0
HKD3_k127_2926754_1 serine threonine protein kinase K08282 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000105 306.0
HKD3_k127_2926754_2 Phospholipase D Active site motif K01115 - 3.1.4.4 0.000000000000000000000000000000000000000000000000000000000002197 220.0
HKD3_k127_2926754_3 signal peptide protein - - - 0.00000000000000000000000000000000000000000000000000000008176 219.0
HKD3_k127_2926754_4 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000003358 164.0
HKD3_k127_2926754_5 - - - - 0.000000000000000000000000000000000000000004347 164.0
HKD3_k127_2926754_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000005974 160.0
HKD3_k127_2926754_7 - - - - 0.0000000000000000000000000000001891 133.0
HKD3_k127_2958443_0 Adenylate cyclase K01768 - 4.6.1.1 8.77e-253 793.0
HKD3_k127_2958443_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 516.0
HKD3_k127_2958443_2 phosphoesterase, PA-phosphatase related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 427.0
HKD3_k127_2958443_3 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000007505 138.0
HKD3_k127_2958443_4 Peptidase M48 Ste24p - - - 0.0000000000174 64.0
HKD3_k127_2983165_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 394.0
HKD3_k127_2983165_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003336 272.0
HKD3_k127_2983165_2 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000002149 241.0
HKD3_k127_2983165_3 Protein of unknown function (DUF3302) - - - 0.00000000000000000001385 99.0
HKD3_k127_2983165_4 Rieske-like [2Fe-2S] domain K05710 - - 0.00000000006143 70.0
HKD3_k127_299186_0 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 630.0
HKD3_k127_299186_1 Amidohydrolase family K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 491.0
HKD3_k127_299186_2 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000005588 220.0
HKD3_k127_299186_3 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000188 224.0
HKD3_k127_299186_4 Transcriptional regulator K04033 - - 0.0000000000000000000000003303 118.0
HKD3_k127_2992800_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 481.0
HKD3_k127_2992800_1 Malate/L-lactate dehydrogenase K13574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 304.0
HKD3_k127_2992800_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001887 260.0
HKD3_k127_299383_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004974 519.0
HKD3_k127_299383_1 ABC transporter transmembrane region K02021 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006556 417.0
HKD3_k127_299383_2 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 364.0
HKD3_k127_299383_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 331.0
HKD3_k127_299383_4 - - - - 0.000000000000000000000000000000000000000000000000000000000003734 218.0
HKD3_k127_299383_5 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000006039 174.0
HKD3_k127_299383_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000003278 155.0
HKD3_k127_299383_7 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000586 141.0
HKD3_k127_299383_8 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000001013 117.0
HKD3_k127_301473_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 2.964e-229 715.0
HKD3_k127_301473_1 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 559.0
HKD3_k127_301473_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 382.0
HKD3_k127_301473_3 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001626 301.0
HKD3_k127_3023223_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 2.143e-305 949.0
HKD3_k127_3023223_1 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000001163 220.0
HKD3_k127_3023223_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000000000000000000000000000000000116 134.0
HKD3_k127_305630_0 Bacterial protein of unknown function (DUF853) K06915 - - 1.511e-236 740.0
HKD3_k127_305630_1 Belongs to the peptidase S8 family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 337.0
HKD3_k127_305630_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004748 244.0
HKD3_k127_305630_3 - - - - 0.00000000000000000000000000000000001363 156.0
HKD3_k127_305630_4 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000003621 96.0
HKD3_k127_305630_5 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 0.00000000000000001779 96.0
HKD3_k127_305630_6 Sugar-transfer associated ATP-grasp - - - 0.0000000000006082 81.0
HKD3_k127_3063099_0 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000763 151.0
HKD3_k127_3063099_1 Positively regulates the transcription of the maltose regulon whose gene products are responsible for uptake and catabolism of malto-oligosaccharides. Binds and recognizes a DNA motif (called the malT box) 5'-GGA TG GA-3' K03556 GO:0003674,GO:0003700,GO:0005488,GO:0005515,GO:0005975,GO:0006355,GO:0008150,GO:0008152,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030246,GO:0031323,GO:0031326,GO:0042802,GO:0044238,GO:0048031,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070492,GO:0071704,GO:0080090,GO:0140110,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000003944 112.0
HKD3_k127_3072389_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 2.023e-200 632.0
HKD3_k127_3072389_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.505e-198 626.0
HKD3_k127_3072389_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 424.0
HKD3_k127_3072389_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 420.0
HKD3_k127_3072389_4 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 377.0
HKD3_k127_3072389_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 357.0
HKD3_k127_3072389_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002235 252.0
HKD3_k127_3072389_7 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000004449 138.0
HKD3_k127_3081334_0 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 375.0
HKD3_k127_3081334_1 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000004315 173.0
HKD3_k127_3081334_2 Nuclear protein SET K07117 - - 0.00000000000000006966 85.0
HKD3_k127_3104923_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 473.0
HKD3_k127_3104923_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 352.0
HKD3_k127_3104923_2 Protein of unknown function (DUF1349) - - - 0.000000000165 64.0
HKD3_k127_3117762_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 351.0
HKD3_k127_3117762_1 FR47-like protein - - - 0.000000000000000000000000000000000000000000003926 180.0
HKD3_k127_3117762_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000003576 164.0
HKD3_k127_3117762_3 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000004485 152.0
HKD3_k127_3117762_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000008187 135.0
HKD3_k127_3117762_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000001933 83.0
HKD3_k127_3134749_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 299.0
HKD3_k127_3134749_1 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008081 265.0
HKD3_k127_3134749_2 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000006016 83.0
HKD3_k127_3194994_0 Flavin containing amine oxidoreductase - - - 2.26e-297 930.0
HKD3_k127_3194994_1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000153 250.0
HKD3_k127_3194994_2 WHG domain - - - 0.000000000000000000000000000000000000000000000000000000002726 207.0
HKD3_k127_3194994_3 Beta-lactamase superfamily domain - - - 0.00000002214 60.0
HKD3_k127_3212496_0 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000196 195.0
HKD3_k127_3212496_1 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.00000000000000000000000000000000000000000005648 160.0
HKD3_k127_3212496_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000005404 122.0
HKD3_k127_3221793_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 414.0
HKD3_k127_3221793_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005559 385.0
HKD3_k127_3221793_2 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 372.0
HKD3_k127_3221793_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000825 312.0
HKD3_k127_3221793_4 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004407 274.0
HKD3_k127_3221793_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000007533 145.0
HKD3_k127_3234999_0 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 520.0
HKD3_k127_3234999_1 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000000000007425 87.0
HKD3_k127_3234999_2 Protein of unknown function (DUF3604) - - - 0.000000000000001054 81.0
HKD3_k127_3235976_0 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 309.0
HKD3_k127_3235976_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 282.0
HKD3_k127_3235976_2 transcriptional Regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000007094 228.0
HKD3_k127_3367542_0 Sulfide dehydrogenase K05301,K17218 - 1.8.2.1,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 591.0
HKD3_k127_3367542_1 exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 517.0
HKD3_k127_3367542_2 Drug metabolite transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 364.0
HKD3_k127_3367542_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 290.0
HKD3_k127_3367542_4 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000001368 147.0
HKD3_k127_3367542_5 Belongs to the ClpA ClpB family K03694 - - 0.0000000000000000000000000001719 115.0
HKD3_k127_3367542_6 Cytochrome c, class I - - - 0.0000000000000000000008621 111.0
HKD3_k127_3367542_7 FAD dependent oxidoreductase - - - 0.0000000006682 67.0
HKD3_k127_340843_0 Shikimate dehydrogenase substrate binding domain protein K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 381.0
HKD3_k127_340843_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 361.0
HKD3_k127_340843_2 acetolactate synthase large subunit K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000005558 211.0
HKD3_k127_3444891_0 PFAM regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005349 535.0
HKD3_k127_3444891_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 319.0
HKD3_k127_3444891_2 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001897 297.0
HKD3_k127_3444891_3 EamA-like transporter family K15268 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005968 274.0
HKD3_k127_3444891_4 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000001463 171.0
HKD3_k127_3444891_5 Peptidase family M48 - - - 0.0000000000000000000000000002865 121.0
HKD3_k127_3444891_6 - - - - 0.0000000000000000000009868 111.0
HKD3_k127_3444891_7 - - - - 0.000000001729 65.0
HKD3_k127_3444891_8 gluconolactonase activity - - - 0.00000003197 67.0
HKD3_k127_346823_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 510.0
HKD3_k127_346823_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 367.0
HKD3_k127_346823_2 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000001498 192.0
HKD3_k127_346823_3 Cation efflux family - - - 0.00000000000000000000000000000005214 126.0
HKD3_k127_346823_4 - - - - 0.00000000000000000000000001321 121.0
HKD3_k127_347054_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 401.0
HKD3_k127_347054_1 COG0156 7-keto-8-aminopelargonate synthetase and related enzymes K21784 GO:0003674,GO:0005488,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016999,GO:0017000,GO:0017144,GO:0019842,GO:0036094,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0048037,GO:0070279,GO:0070280,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 326.0
HKD3_k127_347054_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000000000000000000000000000001654 158.0
HKD3_k127_347949_0 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008195 274.0
HKD3_k127_347949_1 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007237 276.0
HKD3_k127_347949_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000002087 178.0
HKD3_k127_3621672_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 9.53e-213 672.0
HKD3_k127_3621672_1 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 381.0
HKD3_k127_3621672_2 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000297 205.0
HKD3_k127_3621672_3 Transcriptional regulatory protein, C terminal K22486 - - 0.000000006207 68.0
HKD3_k127_3621672_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0001495 54.0
HKD3_k127_3624361_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 434.0
HKD3_k127_3624361_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 414.0
HKD3_k127_3624361_2 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 389.0
HKD3_k127_3624361_3 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 357.0
HKD3_k127_3624361_4 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 325.0
HKD3_k127_3624361_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000002018 234.0
HKD3_k127_3624361_6 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000003108 149.0
HKD3_k127_3624361_7 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000003652 137.0
HKD3_k127_3631686_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01856,K19802 - 5.1.1.20,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 518.0
HKD3_k127_3631686_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 484.0
HKD3_k127_3631686_10 PFAM Di-haem cytochrome c - - - 0.0000000000000000000000000000000006742 136.0
HKD3_k127_3631686_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000002162 77.0
HKD3_k127_3631686_2 PFAM ATP-binding region ATPase domain protein K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 360.0
HKD3_k127_3631686_3 PFAM response regulator receiver K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 299.0
HKD3_k127_3631686_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001059 302.0
HKD3_k127_3631686_5 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000000000000001178 230.0
HKD3_k127_3631686_6 SnoaL-like domain K01822 - 5.3.3.1 0.00000000000000000000000000000000000000000003616 168.0
HKD3_k127_3631686_7 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000001383 160.0
HKD3_k127_3631686_8 FCD - - - 0.000000000000000000000000000000000000002682 155.0
HKD3_k127_3631686_9 Domain of unknown function (DUF1924) - - - 0.0000000000000000000000000000000004786 135.0
HKD3_k127_3632902_0 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 526.0
HKD3_k127_3632902_1 transporter component K07112 - - 0.0000000000000000000000000000000000000000000000000001301 188.0
HKD3_k127_3632902_2 transporter component K07112 - - 0.0000000000000000000000000000000000000000000000000001701 192.0
HKD3_k127_3632902_3 Dihydrodipicolinate synthetase family K01714,K13876 - 4.2.1.43,4.3.3.7 0.000000000000000000000000000000000000002294 147.0
HKD3_k127_3639965_0 Transposase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 527.0
HKD3_k127_3639965_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 445.0
HKD3_k127_3639965_10 - - - - 0.000000000000000000000000000000000000000000000004776 181.0
HKD3_k127_3639965_11 Glutathione-dependent formaldehyde-activating enzyme - - - 0.00000000000000000000000000000000000000000000002545 175.0
HKD3_k127_3639965_12 Cupin domain - - - 0.000000000000000000000000000000000000003476 155.0
HKD3_k127_3639965_13 Protein of unknown function (DUF3108) - - - 0.000000000005788 79.0
HKD3_k127_3639965_2 Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate K01815 - 5.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 415.0
HKD3_k127_3639965_3 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 342.0
HKD3_k127_3639965_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002959 274.0
HKD3_k127_3639965_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000005303 267.0
HKD3_k127_3639965_6 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000000000000000000254 215.0
HKD3_k127_3639965_7 - - - - 0.0000000000000000000000000000000000000000000000000000005326 201.0
HKD3_k127_3639965_8 Protein of unknown function (DUF4239) - - - 0.00000000000000000000000000000000000000000000000001413 188.0
HKD3_k127_3639965_9 Phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000001152 176.0
HKD3_k127_3649209_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 440.0
HKD3_k127_3649209_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 400.0
HKD3_k127_3649209_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 343.0
HKD3_k127_3649209_3 Domain of unknown function (DUF1932) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 313.0
HKD3_k127_3649209_4 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 299.0
HKD3_k127_3649209_5 Sugar (and other) transporter K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009212 291.0
HKD3_k127_3649209_6 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000004737 158.0
HKD3_k127_3649209_7 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000002458 114.0
HKD3_k127_3649209_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K15520 - 2.3.1.189 0.00000000000000000001069 99.0
HKD3_k127_3653490_0 Belongs to the pirin family K06911 - - 0.000000000000000000003839 93.0
HKD3_k127_3653490_1 - - - - 0.00000000000000000007264 103.0
HKD3_k127_3653490_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00003852 47.0
HKD3_k127_3655598_0 Alpha beta hydrolase - - - 9.967e-267 843.0
HKD3_k127_3655598_1 Acts as a magnesium transporter K06213 - - 5.404e-201 639.0
HKD3_k127_3655598_2 Phosphatase K01090 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 539.0
HKD3_k127_3655598_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 313.0
HKD3_k127_3655598_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 304.0
HKD3_k127_3655598_5 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000002491 262.0
HKD3_k127_3655598_6 TonB C terminal K03832 - - 0.0000000000004978 69.0
HKD3_k127_3671519_0 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 379.0
HKD3_k127_3671519_1 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 359.0
HKD3_k127_3671692_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 436.0
HKD3_k127_3671692_1 Sulfotransferase domain - - - 0.0000000000000000000000000000000000001807 147.0
HKD3_k127_3671937_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.14e-202 640.0
HKD3_k127_3671937_1 Glycosyltransferase WbsX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 423.0
HKD3_k127_3671937_10 zinc protease protein - - - 0.0000000000000003239 83.0
HKD3_k127_3671937_2 Glycosyltransferases involved in cell wall biogenesis K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 346.0
HKD3_k127_3671937_3 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000008403 199.0
HKD3_k127_3671937_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000002911 195.0
HKD3_k127_3671937_5 Ribosomal protein S18 K02963 - - 0.0000000000000000000000000000000000003124 141.0
HKD3_k127_3671937_6 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000001193 136.0
HKD3_k127_3671937_7 PFAM Citrate transporter - - - 0.00000000000000000000000000000001216 128.0
HKD3_k127_3671937_8 Universal stress protein - - - 0.00000000000000000000000002036 113.0
HKD3_k127_3671937_9 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000005376 93.0
HKD3_k127_368369_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 363.0
HKD3_k127_368369_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 319.0
HKD3_k127_368369_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002519 257.0
HKD3_k127_3684070_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 576.0
HKD3_k127_3684070_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 428.0
HKD3_k127_3684070_2 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000003233 175.0
HKD3_k127_3684070_3 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000002412 131.0
HKD3_k127_3684070_4 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000000000000004743 102.0
HKD3_k127_3687517_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1239.0
HKD3_k127_3697619_0 ABC-type sugar transport system periplasmic component K02027 - - 8.835e-203 641.0
HKD3_k127_3697619_1 TOBE domain K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 551.0
HKD3_k127_3697619_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 459.0
HKD3_k127_3697619_3 PFAM binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 457.0
HKD3_k127_3697619_4 Dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 422.0
HKD3_k127_3697619_5 Alpha beta hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000001639 215.0
HKD3_k127_3697619_6 major facilitator superfamily MFS_1 K08226 - - 0.0000000000000000000000000000000000000000000000105 190.0
HKD3_k127_369871_0 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 389.0
HKD3_k127_369871_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000001744 212.0
HKD3_k127_369871_2 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000006636 189.0
HKD3_k127_3699293_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000802 269.0
HKD3_k127_3699293_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000182 256.0
HKD3_k127_3699293_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000002003 63.0
HKD3_k127_3699293_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001644 251.0
HKD3_k127_3699293_3 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000007104 174.0
HKD3_k127_3699293_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000006704 151.0
HKD3_k127_3699293_5 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000499 129.0
HKD3_k127_3699293_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0008150,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000006655 119.0
HKD3_k127_3699293_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000004035 93.0
HKD3_k127_3699293_8 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000002905 93.0
HKD3_k127_3699293_9 Ribosomal protein L30p/L7e K02907 - - 0.000000000000118 73.0
HKD3_k127_3704215_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1166.0
HKD3_k127_3704215_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 372.0
HKD3_k127_3704215_10 - - - - 0.000004138 57.0
HKD3_k127_3704215_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 289.0
HKD3_k127_3704215_3 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000003658 271.0
HKD3_k127_3704215_4 Response regulator of the LytR AlgR family K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005796 258.0
HKD3_k127_3704215_5 pyrroloquinoline quinone binding - - - 0.000000000000000000000000000000000000000000000000000000000002836 223.0
HKD3_k127_3704215_6 Histidine kinase - - - 0.0000000000000000000000000000000000000000000001181 186.0
HKD3_k127_3704215_7 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000002118 174.0
HKD3_k127_3704215_8 component of anaerobic dehydrogenases - - - 0.000000000000000000000000002399 121.0
HKD3_k127_3704215_9 Histidine kinase - - - 0.000000000002997 80.0
HKD3_k127_3706671_0 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 5.21e-260 823.0
HKD3_k127_3706671_1 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 510.0
HKD3_k127_3706671_2 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 451.0
HKD3_k127_3706671_3 abc transporter, permease K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 406.0
HKD3_k127_3706671_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 332.0
HKD3_k127_3706671_5 MaoC like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003186 270.0
HKD3_k127_3706771_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 6.039e-226 703.0
HKD3_k127_3706771_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 321.0
HKD3_k127_3706771_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 294.0
HKD3_k127_3724441_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 478.0
HKD3_k127_3724441_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009866 427.0
HKD3_k127_3724441_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 419.0
HKD3_k127_3724441_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001104 280.0
HKD3_k127_3724441_4 Phospholipase D. Active site motifs. K06132 - - 0.0000000000000000000000000000000000000000000000000000000000002677 220.0
HKD3_k127_3724441_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000003817 179.0
HKD3_k127_3724441_6 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000001616 118.0
HKD3_k127_3724441_7 NmrA-like family - - - 0.000000000000000002218 100.0
HKD3_k127_3732948_0 glycosyl transferase family 2 K20444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 624.0
HKD3_k127_3732948_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 479.0
HKD3_k127_3732948_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002678 280.0
HKD3_k127_3732948_11 - - - - 0.000000000000000000000000000000000000000000000000000000000001074 227.0
HKD3_k127_3732948_12 PFAM glycosyl transferase family 9 K02843 - - 0.0000000000000000000000000000000000000000000000000000000001058 217.0
HKD3_k127_3732948_13 ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000004369 203.0
HKD3_k127_3732948_14 - - - - 0.0000000000000000000000000000000000000000000001151 192.0
HKD3_k127_3732948_15 glycosyl transferase family 2 K20444 - - 0.0000000000000000000000000000000000000001221 172.0
HKD3_k127_3732948_16 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000007562 140.0
HKD3_k127_3732948_17 - - - - 0.0000000000000000000000000000000632 140.0
HKD3_k127_3732948_18 Kdo2-lipid A biosynthetic process - - - 0.00000000000000000000000004427 118.0
HKD3_k127_3732948_19 - - - - 0.00000000009339 69.0
HKD3_k127_3732948_2 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000663 439.0
HKD3_k127_3732948_21 - K02463 - - 0.000009757 57.0
HKD3_k127_3732948_22 protein conserved in bacteria - - - 0.0008925 53.0
HKD3_k127_3732948_3 pfam abc K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 418.0
HKD3_k127_3732948_4 TIGRFAM Undecaprenyl-phosphate glucose phosphotransferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 396.0
HKD3_k127_3732948_5 Glycosyl transferase, group 1 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 369.0
HKD3_k127_3732948_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 354.0
HKD3_k127_3732948_7 PFAM Tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 338.0
HKD3_k127_3732948_8 Male sterility protein K15856,K22252 - 1.1.1.135,1.1.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 310.0
HKD3_k127_3732948_9 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009412 301.0
HKD3_k127_3741713_0 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000211 291.0
HKD3_k127_3741713_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000004767 240.0
HKD3_k127_3741713_2 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000003574 210.0
HKD3_k127_3746698_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 516.0
HKD3_k127_3746698_1 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 294.0
HKD3_k127_3746698_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000003675 250.0
HKD3_k127_3746698_3 serine threonine protein kinase - - - 0.00000000000000000000000000000284 124.0
HKD3_k127_3746698_4 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000009225 109.0
HKD3_k127_3759019_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 599.0
HKD3_k127_3759019_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 478.0
HKD3_k127_3759019_10 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000000000000000008938 198.0
HKD3_k127_3759019_11 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000001533 194.0
HKD3_k127_3759019_12 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000004671 160.0
HKD3_k127_3759019_13 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000007663 153.0
HKD3_k127_3759019_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000185 137.0
HKD3_k127_3759019_15 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000004099 140.0
HKD3_k127_3759019_16 Bacterial SH3 domain - - - 0.000000000000000000000000000001485 134.0
HKD3_k127_3759019_17 Integral membrane protein (DUF2244) - - - 0.00000001038 64.0
HKD3_k127_3759019_2 Cytochrome C oxidase subunit II, transmembrane domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 486.0
HKD3_k127_3759019_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 401.0
HKD3_k127_3759019_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 307.0
HKD3_k127_3759019_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 312.0
HKD3_k127_3759019_6 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 308.0
HKD3_k127_3759019_7 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000004104 232.0
HKD3_k127_3759019_8 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000000000000000000000000000000000000000000000001587 227.0
HKD3_k127_3759019_9 AAA domain - - - 0.000000000000000000000000000000000000000000000000000006406 209.0
HKD3_k127_3759706_0 Transcriptional regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 311.0
HKD3_k127_3759706_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 312.0
HKD3_k127_3759706_2 dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 294.0
HKD3_k127_3759706_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000001611 228.0
HKD3_k127_3759706_4 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000227 197.0
HKD3_k127_3759706_5 Eukaryotic integral membrane protein (DUF1751) - - - 0.00000000000000000000000000000000000000000000000008964 199.0
HKD3_k127_3759706_6 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000000000000007161 171.0
HKD3_k127_3759706_7 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000001294 166.0
HKD3_k127_3759706_8 - - - - 0.000000000000000000000000000001694 126.0
HKD3_k127_3759706_9 Hemerythrin HHE cation binding domain - - - 0.0000008759 59.0
HKD3_k127_3765937_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 3.017e-196 625.0
HKD3_k127_3765937_1 COG0010 Arginase agmatinase formimionoglutamate hydrolase, arginase family K00819 - 2.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 532.0
HKD3_k127_3765937_10 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000001411 128.0
HKD3_k127_3765937_11 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000003175 115.0
HKD3_k127_3765937_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000008888 119.0
HKD3_k127_3765937_13 SH3 domain - - - 0.000000000000000000000009456 109.0
HKD3_k127_3765937_2 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 452.0
HKD3_k127_3765937_3 5'-nucleotidase K01081 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 412.0
HKD3_k127_3765937_4 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 356.0
HKD3_k127_3765937_5 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 344.0
HKD3_k127_3765937_6 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001796 287.0
HKD3_k127_3765937_7 Belongs to the peptidase S11 family K07258,K07262 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000002377 224.0
HKD3_k127_3765937_8 protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000000003042 187.0
HKD3_k127_3765937_9 Uncharacterised protein family (UPF0227) K07000 - - 0.0000000000000000000000000000000000000000001366 181.0
HKD3_k127_3769415_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 326.0
HKD3_k127_3769415_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000002806 241.0
HKD3_k127_3769415_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000003585 221.0
HKD3_k127_3769415_3 Psort location CytoplasmicMembrane, score 9.46 - - - 0.000000000000000000000003397 105.0
HKD3_k127_3769415_5 Lysozyme inhibitor LprI - - - 0.0002252 49.0
HKD3_k127_3778452_0 ATP-dependent DNA ligase K01971 - 6.5.1.1 5.264e-219 707.0
HKD3_k127_3778452_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 362.0
HKD3_k127_3778452_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 306.0
HKD3_k127_3778452_3 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000002433 187.0
HKD3_k127_3778452_4 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000002424 189.0
HKD3_k127_3778452_5 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000001486 114.0
HKD3_k127_3778452_6 Glycine-zipper domain - - - 0.00000000000000000000007355 109.0
HKD3_k127_3778452_7 - - - - 0.000000000000002859 85.0
HKD3_k127_3784529_0 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000006321 220.0
HKD3_k127_3784529_1 Belongs to the ATP-dependent AMP-binding enzyme family. MenE subfamily K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000000000000004212 213.0
HKD3_k127_3787071_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 297.0
HKD3_k127_3787071_1 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000626 250.0
HKD3_k127_3787071_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000002715 207.0
HKD3_k127_3787071_3 Response regulator receiver - - - 0.00000000000000000000001327 106.0
HKD3_k127_3787071_4 - - - - 0.00000000000000000604 91.0
HKD3_k127_3787339_0 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 313.0
HKD3_k127_3787339_1 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000008439 138.0
HKD3_k127_3787339_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003824,GO:0004654,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.8 0.00000000000001036 74.0
HKD3_k127_3810330_0 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000001189 235.0
HKD3_k127_3810330_1 - - - - 0.0000000000000000004619 100.0
HKD3_k127_3821453_0 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 577.0
HKD3_k127_3821453_1 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000001994 197.0
HKD3_k127_3821453_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000004416 168.0
HKD3_k127_3821453_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000009207 125.0
HKD3_k127_3821837_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 584.0
HKD3_k127_3821837_1 TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. DOES NOT COUPLE THE REDOX REACTION TO PROTON TRANSLOCATION. Interpro FAD-dependent pyridine K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 468.0
HKD3_k127_3821837_2 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 337.0
HKD3_k127_3821837_3 effector of murein hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003443 274.0
HKD3_k127_3821837_4 effector of murein hydrolase LrgA K06518 - - 0.000000000000000000003616 109.0
HKD3_k127_3821837_5 Phospholipid - - - 0.00001197 57.0
HKD3_k127_3823503_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 417.0
HKD3_k127_3823503_1 peptidase - - - 0.00000000000000000000000000000000000000008215 171.0
HKD3_k127_3828423_0 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 347.0
HKD3_k127_3828423_1 Putative prokaryotic signal transducing protein - - - 0.00000000000000000001014 95.0
HKD3_k127_3828423_2 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000003503 91.0
HKD3_k127_3831637_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 430.0
HKD3_k127_3831637_1 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001304 272.0
HKD3_k127_3831637_2 Sodium Bile acid symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002366 261.0
HKD3_k127_3831637_3 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000004085 202.0
HKD3_k127_3831637_4 Histidine kinase - - - 0.000000000000000000000000000000000000000005954 159.0
HKD3_k127_3845132_0 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 8.261e-206 659.0
HKD3_k127_3845132_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 580.0
HKD3_k127_3845132_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 489.0
HKD3_k127_3845132_3 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 465.0
HKD3_k127_3845132_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007515 276.0
HKD3_k127_3845132_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000003634 223.0
HKD3_k127_3845132_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000007705 181.0
HKD3_k127_3845132_7 Shikimate kinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000000000000008115 186.0
HKD3_k127_3845132_8 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000871 111.0
HKD3_k127_3845132_9 Protein of unknown function (DUF2798) - - - 0.0000000000000233 79.0
HKD3_k127_3845862_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.105e-258 822.0
HKD3_k127_3845862_1 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 453.0
HKD3_k127_3845862_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 336.0
HKD3_k127_3845862_3 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 323.0
HKD3_k127_3845862_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001661 275.0
HKD3_k127_3845862_5 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000000000000004516 187.0
HKD3_k127_3845969_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 505.0
HKD3_k127_3845969_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 336.0
HKD3_k127_3845969_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 323.0
HKD3_k127_3845969_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 323.0
HKD3_k127_3845969_4 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 285.0
HKD3_k127_3845969_5 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002216 278.0
HKD3_k127_3845969_6 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008093 252.0
HKD3_k127_3845969_7 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.000000000000000000000000000000000000000000000000000000008767 202.0
HKD3_k127_3845969_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000006654 151.0
HKD3_k127_3845969_9 Tfp pilus assembly protein FimV - - - 0.0000000000003872 81.0
HKD3_k127_384725_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 354.0
HKD3_k127_384725_1 Asp Glu hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000003655 182.0
HKD3_k127_384725_2 Rhodanese Homology Domain - - - 0.00000000000000005198 91.0
HKD3_k127_384725_3 Beta-lactamase superfamily domain - - - 0.0000000000000002153 81.0
HKD3_k127_3850015_0 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002185 241.0
HKD3_k127_3850015_1 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.00000000000000000000000000000000000000000000000000002339 190.0
HKD3_k127_3850015_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000008749 190.0
HKD3_k127_3850015_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000001059 197.0
HKD3_k127_385194_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 3.265e-232 739.0
HKD3_k127_385194_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.000000000000000000000000000000000000000000000008394 183.0
HKD3_k127_385194_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000001196 126.0
HKD3_k127_3856451_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 398.0
HKD3_k127_3856451_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000225 274.0
HKD3_k127_3856451_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002912 271.0
HKD3_k127_3856451_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.0000000165 59.0
HKD3_k127_385716_0 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 490.0
HKD3_k127_385716_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000003983 127.0
HKD3_k127_385716_2 PFAM acyl-coA-binding protein, ACBP - - - 0.0000000000000000000000001008 109.0
HKD3_k127_3860414_0 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 404.0
HKD3_k127_3860414_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 378.0
HKD3_k127_3860414_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 342.0
HKD3_k127_3860414_3 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 338.0
HKD3_k127_3860414_4 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001647 297.0
HKD3_k127_3860414_5 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000006568 205.0
HKD3_k127_3860414_6 ChaC-like protein K07232 - - 0.0000000000000000000000000000000000000000000000000000009672 203.0
HKD3_k127_3860414_7 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000006569 193.0
HKD3_k127_3898094_0 Amidohydrolase family - - - 2.327e-254 807.0
HKD3_k127_3898094_1 glucuronate isomerase K01812 - 5.3.1.12 3.415e-234 734.0
HKD3_k127_3898094_10 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000344 259.0
HKD3_k127_3898094_11 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000004387 229.0
HKD3_k127_3898094_12 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000001172 178.0
HKD3_k127_3898094_13 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000000001066 168.0
HKD3_k127_3898094_14 ABC transporter K09810 - - 0.00000000000000000000000000000000000000001577 155.0
HKD3_k127_3898094_15 Type III secretion system lipoprotein chaperone (YscW) K09914 - - 0.0000000000000000000000000574 115.0
HKD3_k127_3898094_2 Belongs to the mannitol dehydrogenase family K00040 - 1.1.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 505.0
HKD3_k127_3898094_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 494.0
HKD3_k127_3898094_4 Bacterial extracellular solute-binding protein K02012,K11081 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 451.0
HKD3_k127_3898094_5 peptidase m48, ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 432.0
HKD3_k127_3898094_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 399.0
HKD3_k127_3898094_7 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 337.0
HKD3_k127_3898094_8 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 323.0
HKD3_k127_3898094_9 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 305.0
HKD3_k127_3920345_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.315e-208 655.0
HKD3_k127_3920345_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 467.0
HKD3_k127_3920345_2 PFAM Spermine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000007167 256.0
HKD3_k127_3920345_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000002599 263.0
HKD3_k127_3920345_4 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000001568 212.0
HKD3_k127_3920345_5 Alpha beta hydrolase K00433 - 1.11.1.10 0.00000000000000000000000000000000000000000000004007 188.0
HKD3_k127_3920345_6 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000000004181 182.0
HKD3_k127_3920345_7 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000001325 73.0
HKD3_k127_393014_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
HKD3_k127_393014_1 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 340.0
HKD3_k127_393014_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 305.0
HKD3_k127_393014_3 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000004732 228.0
HKD3_k127_3942980_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 584.0
HKD3_k127_3942980_1 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 545.0
HKD3_k127_3942980_2 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001185 270.0
HKD3_k127_3942980_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000006648 196.0
HKD3_k127_3942980_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000002017 102.0
HKD3_k127_3942980_6 NAD dependent epimerase/dehydratase family - GO:0003674,GO:0003824,GO:0004033,GO:0008106,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0055114 - 0.0000000000002508 75.0
HKD3_k127_3942980_7 AAA domain - - - 0.000002969 61.0
HKD3_k127_3942980_9 amidohydrolase - - - 0.0005804 53.0
HKD3_k127_3943807_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003067 251.0
HKD3_k127_3943807_1 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000007122 205.0
HKD3_k127_3943807_2 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000001838 160.0
HKD3_k127_3943807_3 Phage integrase family - - - 0.00000000000000000002752 92.0
HKD3_k127_3943807_4 Belongs to the 'phage' integrase family - - - 0.000000003586 64.0
HKD3_k127_3945426_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.279e-240 750.0
HKD3_k127_3945426_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 2.628e-223 695.0
HKD3_k127_3945426_10 Sulfurtransferase TusA - - - 0.000000000000000000000000000000000000000000000000008949 197.0
HKD3_k127_3945426_11 - - - - 0.00000000000000000000000000000000000000000000000005892 191.0
HKD3_k127_3945426_12 DsrH like protein K07237 - - 0.0000000000000000000001081 114.0
HKD3_k127_3945426_13 TIGRFAM CRISPR-associated protein - - - 0.000000000000003936 86.0
HKD3_k127_3945426_14 - - - - 0.000000000000004948 83.0
HKD3_k127_3945426_15 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00001821 46.0
HKD3_k127_3945426_2 Fe-S oxidoreductase K21834 - - 3.691e-219 685.0
HKD3_k127_3945426_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 472.0
HKD3_k127_3945426_4 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 393.0
HKD3_k127_3945426_5 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 319.0
HKD3_k127_3945426_6 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008763 252.0
HKD3_k127_3945426_7 DsrE/DsrF-like family K07235 - - 0.0000000000000000000000000000000000000000000000000000000000025 209.0
HKD3_k127_3945426_8 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000003172 195.0
HKD3_k127_3945426_9 Sulfur relay protein TusC DsrF K07236 - - 0.0000000000000000000000000000000000000000000000000000006171 194.0
HKD3_k127_3947766_0 Protein of unknown function (DUF3141) - - - 3.68e-252 794.0
HKD3_k127_3949291_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0 1533.0
HKD3_k127_3949291_1 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 453.0
HKD3_k127_3949291_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 417.0
HKD3_k127_3949291_3 Histidine kinase K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 406.0
HKD3_k127_3949291_4 Parallel beta-helix repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 348.0
HKD3_k127_3949291_5 YaeQ family - - - 0.00000000000000000000000000000000000000000000000000000000000000000008871 237.0
HKD3_k127_3949291_6 - - - - 0.0000000000000000000000000000000000000000212 164.0
HKD3_k127_395064_0 type IV-A pilus assembly ATPase PilB K02652 - - 4.521e-249 781.0
HKD3_k127_395064_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 612.0
HKD3_k127_395064_10 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000008282 219.0
HKD3_k127_395064_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000001736 201.0
HKD3_k127_395064_12 Legume lectin domain - - - 0.00000000000000000000000000000000000000000000005783 185.0
HKD3_k127_395064_13 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000001596 169.0
HKD3_k127_395064_14 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000007505 125.0
HKD3_k127_395064_15 DNA gyrase inhibitor YacG - - - 0.000000000000000000005042 94.0
HKD3_k127_395064_16 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000001039 87.0
HKD3_k127_395064_17 integral membrane protein - - - 0.00000000000001271 83.0
HKD3_k127_395064_2 PFAM type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 532.0
HKD3_k127_395064_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 501.0
HKD3_k127_395064_4 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 454.0
HKD3_k127_395064_5 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 374.0
HKD3_k127_395064_6 Protein of unknown function (DUF815) K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 368.0
HKD3_k127_395064_7 Thiamine monophosphate synthase K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 340.0
HKD3_k127_395064_8 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 295.0
HKD3_k127_395064_9 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000002012 263.0
HKD3_k127_3969491_0 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 428.0
HKD3_k127_3969491_1 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 386.0
HKD3_k127_3973584_0 Serine dehydratase beta chain K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002546 289.0
HKD3_k127_3973584_1 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000003073 221.0
HKD3_k127_3973584_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000006288 89.0
HKD3_k127_397919_0 Aminotransferase class-V K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 440.0
HKD3_k127_397919_1 AraC-like ligand binding domain - - - 0.00000000000000000000000000000000000000001454 162.0
HKD3_k127_397919_2 - - - - 0.000000000000000000000000000000000514 135.0
HKD3_k127_397919_4 Protein of unknown function (DUF2970) - - - 0.0000000008194 63.0
HKD3_k127_397972_0 ABC transporter transmembrane region K06147 - - 5.4e-259 837.0
HKD3_k127_397972_1 RESPONSE REGULATOR receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 471.0
HKD3_k127_397972_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 420.0
HKD3_k127_397972_3 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 349.0
HKD3_k127_397972_4 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 338.0
HKD3_k127_397972_5 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 316.0
HKD3_k127_397972_6 D-alanyl-D-alanine carboxypeptidase K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007818 280.0
HKD3_k127_397972_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000003306 211.0
HKD3_k127_397972_8 PFAM phosphoesterase PA-phosphatase related K09474 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.1.3.2 0.000000000000003968 79.0
HKD3_k127_4001946_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.034e-210 671.0
HKD3_k127_4004817_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 3.6e-305 957.0
HKD3_k127_4004817_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 354.0
HKD3_k127_4004817_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000268 85.0
HKD3_k127_4004817_2 Tetratricopeptide repeat K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009982 275.0
HKD3_k127_4004817_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001796 248.0
HKD3_k127_4004817_4 oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000003034 257.0
HKD3_k127_4004817_5 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000005064 205.0
HKD3_k127_4004817_6 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000004931 181.0
HKD3_k127_4004817_7 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000002866 171.0
HKD3_k127_4004817_8 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000000000002324 162.0
HKD3_k127_4004817_9 Malic enzyme K00029 - 1.1.1.40 0.000000000000000000003634 97.0
HKD3_k127_4006272_0 Predicted membrane protein (DUF2339) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 494.0
HKD3_k127_4006272_1 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000001837 171.0
HKD3_k127_4015246_0 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 397.0
HKD3_k127_4015246_1 D-isomer specific 2-hydroxyacid dehydrogenase K16843 - 1.1.1.310 0.0000000000000000000000000000000000000000000000000000000000000000000001681 246.0
HKD3_k127_4015246_2 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846,K16850 - 4.2.1.7,4.4.1.24 0.000000000000004425 74.0
HKD3_k127_4026069_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 334.0
HKD3_k127_4026069_1 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000001789 177.0
HKD3_k127_4026069_2 bacterial (prokaryotic) histone like domain - - - 0.00000000000000000000000000000000001366 136.0
HKD3_k127_4026069_3 - - - - 0.00000000000008987 74.0
HKD3_k127_4054368_0 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 577.0
HKD3_k127_4054368_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002062 268.0
HKD3_k127_4054368_2 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000919 133.0
HKD3_k127_4054368_3 - - - - 0.0000000000000000000000001199 123.0
HKD3_k127_4054368_4 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.00000000000000000005648 90.0
HKD3_k127_4056569_0 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 449.0
HKD3_k127_4056569_1 EVE domain - - - 0.00000000000000000000000000000000000000000000000000161 196.0
HKD3_k127_4056569_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000000000001479 146.0
HKD3_k127_4056569_3 Belongs to the UPF0149 family K09895 - - 0.000000000000000000000006173 113.0
HKD3_k127_4056569_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000004506 97.0
HKD3_k127_4056569_5 TIGRFAM TIGR02449 family protein K09892 - - 0.0000000003748 71.0
HKD3_k127_4094801_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 495.0
HKD3_k127_4094801_1 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003871 255.0
HKD3_k127_4099887_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 537.0
HKD3_k127_4099887_1 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 486.0
HKD3_k127_4099887_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 447.0
HKD3_k127_4099887_3 ABC-type dipeptide transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 383.0
HKD3_k127_4099887_4 Yip1 domain - - - 0.0000000000000000000000000000000003435 142.0
HKD3_k127_4099887_5 oxidation-reduction process - - - 0.00000000000000000000000000000000484 133.0
HKD3_k127_4099887_6 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000001325 90.0
HKD3_k127_4109329_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 4.309e-301 962.0
HKD3_k127_4109329_1 abc transporter K15738 - - 8.093e-205 652.0
HKD3_k127_4109329_10 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000000000000002995 138.0
HKD3_k127_4109329_11 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000009219 136.0
HKD3_k127_4109329_12 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.00000000000000001431 85.0
HKD3_k127_4109329_13 OmpA-like transmembrane domain - - - 0.000000000006881 74.0
HKD3_k127_4109329_14 - - - - 0.00000000008252 67.0
HKD3_k127_4109329_15 - - - - 0.0000657 53.0
HKD3_k127_4109329_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 594.0
HKD3_k127_4109329_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 601.0
HKD3_k127_4109329_4 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 576.0
HKD3_k127_4109329_5 Von Willebrand factor K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 453.0
HKD3_k127_4109329_6 Helix-turn-helix type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 354.0
HKD3_k127_4109329_7 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000007158 241.0
HKD3_k127_4109329_8 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000915 182.0
HKD3_k127_4109329_9 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000002366 188.0
HKD3_k127_4117416_0 Protease prsW family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002122 257.0
HKD3_k127_4117416_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000001586 173.0
HKD3_k127_4124174_0 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000001399 276.0
HKD3_k127_4124174_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000007366 230.0
HKD3_k127_4124174_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001407 162.0
HKD3_k127_4124174_3 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000009812 141.0
HKD3_k127_4124174_4 TPM domain - - - 0.0000000000000000000000000003406 125.0
HKD3_k127_4124174_5 - - - - 0.0000000000000001392 91.0
HKD3_k127_4124174_6 PFAM Sporulation domain protein - - - 0.0000000000001188 80.0
HKD3_k127_4124174_7 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000009255 59.0
HKD3_k127_4135751_0 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000347 241.0
HKD3_k127_4135751_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000002026 216.0
HKD3_k127_4149737_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.406e-310 958.0
HKD3_k127_4164897_0 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 531.0
HKD3_k127_4164897_1 PFAM VWA containing CoxE family protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 430.0
HKD3_k127_4164897_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000001043 217.0
HKD3_k127_4164897_3 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000001912 215.0
HKD3_k127_4164897_4 carbon monoxide dehydrogenase subunit g K09386 - - 0.0000000000000000000000000000000000000000000000001236 183.0
HKD3_k127_4182308_0 nucleoside-diphosphate sugar epimerase - - - 2.886e-205 656.0
HKD3_k127_4182308_1 Peptidase M20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 604.0
HKD3_k127_4182308_2 peptidase, M13 K07386 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 543.0
HKD3_k127_4182308_3 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 430.0
HKD3_k127_4182308_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 430.0
HKD3_k127_4182308_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 406.0
HKD3_k127_4182308_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006055 347.0
HKD3_k127_4182308_7 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000006885 179.0
HKD3_k127_4182308_8 sh3 domain protein - - - 0.00000000000000000000000000000000002834 139.0
HKD3_k127_4182308_9 - - - - 0.00002404 58.0
HKD3_k127_4184169_0 TIGRFAM arginyl-tRNA synthetase K01887 - 6.1.1.19 1.672e-209 664.0
HKD3_k127_4184169_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000103 275.0
HKD3_k127_4184169_2 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001049 274.0
HKD3_k127_4184169_3 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000005847 186.0
HKD3_k127_4184169_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000002034 155.0
HKD3_k127_4184169_5 cell division protein - - - 0.00000000000000000000000000001785 130.0
HKD3_k127_4184169_6 esterase K12686 - - 0.000000000000000000000000000717 124.0
HKD3_k127_4271600_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006658 464.0
HKD3_k127_4271600_1 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 356.0
HKD3_k127_4271600_2 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 342.0
HKD3_k127_4271600_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000134 243.0
HKD3_k127_4271600_4 COGs COG4446 conserved - - - 0.00000000000000000000000000000000000002 151.0
HKD3_k127_4271600_5 Aldo/keto reductase family - - - 0.00000000000000000362 84.0
HKD3_k127_4319234_0 Bifunctional protein RfaE, domain I K21344 - 2.7.1.167 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 396.0
HKD3_k127_4319234_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 364.0
HKD3_k127_4319234_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000005014 143.0
HKD3_k127_4328699_0 Pyridine nucleotide-disulphide oxidoreductase - - - 4.313e-244 771.0
HKD3_k127_4328699_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000002145 215.0
HKD3_k127_4328699_2 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000003184 84.0
HKD3_k127_4330437_0 NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1684.0
HKD3_k127_4336722_0 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 295.0
HKD3_k127_4336722_1 Tartrate K01677 - 4.2.1.2 0.0000000000000000000000000000001204 125.0
HKD3_k127_4336722_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000001589 121.0
HKD3_k127_4336722_3 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.00000000000000000000000003239 111.0
HKD3_k127_4365346_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 9.741e-269 834.0
HKD3_k127_4365346_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 597.0
HKD3_k127_4365346_10 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 318.0
HKD3_k127_4365346_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006039 254.0
HKD3_k127_4365346_12 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000006301 244.0
HKD3_k127_4365346_13 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000588 246.0
HKD3_k127_4365346_14 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000007647 234.0
HKD3_k127_4365346_15 HemY domain protein K02498 - - 0.000000000000000000000000000000000000000000000000000000000000000008951 241.0
HKD3_k127_4365346_16 glycosylase K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000957 198.0
HKD3_k127_4365346_17 OmpW family - - - 0.00000000000000000000000000000000000000000000000000003827 195.0
HKD3_k127_4365346_18 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000006379 196.0
HKD3_k127_4365346_19 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000001787 169.0
HKD3_k127_4365346_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 604.0
HKD3_k127_4365346_20 COG3970 Fumarylacetoacetate (FAA) hydrolase family protein - - - 0.00000000000000000000000000001099 125.0
HKD3_k127_4365346_21 Domain of unknown function (DUF1992) - - - 0.0000000000000000000000005336 109.0
HKD3_k127_4365346_22 Predicted membrane protein (DUF2061) - - - 0.00000000000000000000002872 102.0
HKD3_k127_4365346_23 membrane - - - 0.0000000000000000003394 96.0
HKD3_k127_4365346_24 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000001099 94.0
HKD3_k127_4365346_25 Thioredoxin-like - - - 0.00000000000006886 79.0
HKD3_k127_4365346_26 NADH ubiquinone oxidoreductase 41 kD complex I subunit - - - 0.0000000000001148 81.0
HKD3_k127_4365346_27 membrane - - - 0.00000000008311 69.0
HKD3_k127_4365346_3 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 484.0
HKD3_k127_4365346_4 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 388.0
HKD3_k127_4365346_5 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 379.0
HKD3_k127_4365346_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 376.0
HKD3_k127_4365346_7 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 375.0
HKD3_k127_4365346_8 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 363.0
HKD3_k127_4365346_9 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 326.0
HKD3_k127_4420179_0 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 481.0
HKD3_k127_4420179_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 466.0
HKD3_k127_4420179_2 Histidine kinase K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 362.0
HKD3_k127_4420179_3 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006529 346.0
HKD3_k127_4420179_4 Transcriptional regulatory protein, C terminal K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008588 292.0
HKD3_k127_4420179_5 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000003915 224.0
HKD3_k127_4420179_6 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000009654 209.0
HKD3_k127_4420179_7 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000004403 186.0
HKD3_k127_4420179_8 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000002767 177.0
HKD3_k127_44809_0 Bacterial regulatory protein, Fis family K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 371.0
HKD3_k127_44809_1 response regulator - - - 0.0000000000008281 70.0
HKD3_k127_4531651_0 Belongs to the P(II) protein family K04752 GO:0003674,GO:0005488,GO:0005515,GO:0006808,GO:0008150,GO:0042802,GO:0045848,GO:0048518,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000001488 182.0
HKD3_k127_4531651_1 Ferredoxin - - - 0.000000000000000000000000000000000006352 140.0
HKD3_k127_4531651_2 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000001286 116.0
HKD3_k127_453333_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 5.582e-310 959.0
HKD3_k127_453333_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.858e-305 947.0
HKD3_k127_453333_10 PFAM conserved K07795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 341.0
HKD3_k127_453333_11 Ammonia monooxygenase K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 305.0
HKD3_k127_453333_12 pfkB family carbohydrate kinase K00852,K18478 - 2.7.1.15,2.7.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000000001365 272.0
HKD3_k127_453333_13 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000007167 257.0
HKD3_k127_453333_14 trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000000002846 255.0
HKD3_k127_453333_15 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000000000000000000000000000000004306 223.0
HKD3_k127_453333_16 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000001805 201.0
HKD3_k127_453333_17 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000005086 192.0
HKD3_k127_453333_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000001762 151.0
HKD3_k127_453333_19 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000006991 115.0
HKD3_k127_453333_2 Protein conserved in bacteria K07793 - - 2.533e-213 674.0
HKD3_k127_453333_20 Tripartite tricarboxylate transporter TctB family K07794 - - 0.00000000000000000003992 98.0
HKD3_k127_453333_21 ThiS family K03636 - - 0.000000000001798 78.0
HKD3_k127_453333_22 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000006253 67.0
HKD3_k127_453333_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.000000008726 57.0
HKD3_k127_453333_24 ATP synthase I chain K02116 - - 0.00001164 54.0
HKD3_k127_453333_3 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 567.0
HKD3_k127_453333_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 560.0
HKD3_k127_453333_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 484.0
HKD3_k127_453333_6 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 472.0
HKD3_k127_453333_7 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 360.0
HKD3_k127_453333_8 involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 350.0
HKD3_k127_453333_9 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 347.0
HKD3_k127_4576415_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 491.0
HKD3_k127_4576415_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001633 256.0
HKD3_k127_4576415_2 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000535 198.0
HKD3_k127_4576415_3 Gram-negative porin - - - 0.000000000000000000000000000000000000000000902 170.0
HKD3_k127_4576415_4 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.0000000000000000000000000000000000005218 146.0
HKD3_k127_4576415_5 Saccharopine dehydrogenase NADP binding domain K00329,K00356 - 1.6.5.3,1.6.99.3 0.00009728 45.0
HKD3_k127_4590213_0 PQQ-like domain K00114 - 1.1.2.8 0.0 1031.0
HKD3_k127_4590213_1 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 612.0
HKD3_k127_4590213_10 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000006907 126.0
HKD3_k127_4590213_11 - - - - 0.0000000000000000000009553 111.0
HKD3_k127_4590213_12 4Fe-4S dicluster domain K05796 - - 0.00000000000000000362 84.0
HKD3_k127_4590213_2 Metallo-beta-lactamase superfamily K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 374.0
HKD3_k127_4590213_3 Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 331.0
HKD3_k127_4590213_4 extracellular solute-binding protein, family 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008006 267.0
HKD3_k127_4590213_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003734 257.0
HKD3_k127_4590213_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000001429 222.0
HKD3_k127_4590213_7 - - - - 0.000000000000000000000000000000000000000000006235 179.0
HKD3_k127_4590213_8 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000003716 166.0
HKD3_k127_4590213_9 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000000000000000005273 148.0
HKD3_k127_4603891_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 630.0
HKD3_k127_4603891_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 563.0
HKD3_k127_4603891_10 Ankyrin repeats (3 copies) K06867 - - 0.0000000000000000000000000000000000000000000000000000000000000000003018 250.0
HKD3_k127_4603891_11 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000009578 234.0
HKD3_k127_4603891_12 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000002097 210.0
HKD3_k127_4603891_13 protein conserved in bacteria - - - 0.000000000000000000000000000000004287 145.0
HKD3_k127_4603891_14 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000009277 122.0
HKD3_k127_4603891_15 Evidence 5 No homology to any previously reported sequences - - - 0.0001791 51.0
HKD3_k127_4603891_2 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 390.0
HKD3_k127_4603891_3 PFAM Serine threonine protein kinase-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 378.0
HKD3_k127_4603891_4 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 355.0
HKD3_k127_4603891_5 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004509 355.0
HKD3_k127_4603891_6 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 345.0
HKD3_k127_4603891_7 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 321.0
HKD3_k127_4603891_8 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 318.0
HKD3_k127_4603891_9 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 333.0
HKD3_k127_469556_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 327.0
HKD3_k127_469556_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000004084 141.0
HKD3_k127_469556_2 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000006968 123.0
HKD3_k127_469556_3 EamA-like transporter family - - - 0.00000000000000000000000008983 113.0
HKD3_k127_470142_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 441.0
HKD3_k127_470142_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000001655 130.0
HKD3_k127_470142_2 Sporulation related domain K03749 - - 0.00000000000001196 85.0
HKD3_k127_4721214_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002739 261.0
HKD3_k127_4721214_1 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000002719 161.0
HKD3_k127_4721214_2 Helix-turn-helix XRE-family like proteins - - - 0.00007813 49.0
HKD3_k127_476948_0 Peptidase family M3 K01414 - 3.4.24.70 2.972e-263 850.0
HKD3_k127_476948_10 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000003145 117.0
HKD3_k127_476948_11 Domain of unknown function (DUF4124) - - - 0.000000000004935 76.0
HKD3_k127_476948_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 3.01e-200 639.0
HKD3_k127_476948_3 Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005313 573.0
HKD3_k127_476948_4 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 448.0
HKD3_k127_476948_5 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 408.0
HKD3_k127_476948_6 PFAM ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007539 364.0
HKD3_k127_476948_7 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 349.0
HKD3_k127_476948_8 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000002693 236.0
HKD3_k127_476948_9 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.000000000000000000000000000000000000000000002437 164.0
HKD3_k127_4803066_0 Carbamoyltransferase K00612 - - 2.045e-225 719.0
HKD3_k127_4803066_1 PFAM glycosyl transferase group 1 K00696 - 2.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 477.0
HKD3_k127_4803066_10 D,D-heptose 1,7-bisphosphate phosphatase - - - 0.00000000000000000000000000000000000000000000000000003826 211.0
HKD3_k127_4803066_11 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000004085 196.0
HKD3_k127_4803066_12 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000001219 177.0
HKD3_k127_4803066_13 Adenylyl- / guanylyl cyclase, catalytic domain K01768,K07678 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000005111 133.0
HKD3_k127_4803066_14 Belongs to the ompA family K03640 - - 0.0000000000000000000000000001421 121.0
HKD3_k127_4803066_15 - - - - 0.000000000000005585 84.0
HKD3_k127_4803066_16 Glycosyltransferase Family 4 - - - 0.000000001827 70.0
HKD3_k127_4803066_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 396.0
HKD3_k127_4803066_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 377.0
HKD3_k127_4803066_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 378.0
HKD3_k127_4803066_5 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 336.0
HKD3_k127_4803066_6 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 331.0
HKD3_k127_4803066_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004931 276.0
HKD3_k127_4803066_8 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005549 263.0
HKD3_k127_4803066_9 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004145 244.0
HKD3_k127_4838879_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 330.0
HKD3_k127_4838879_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 299.0
HKD3_k127_4838879_2 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001838 280.0
HKD3_k127_4838879_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000284 253.0
HKD3_k127_4839748_0 CoA-binding domain protein K09181 - - 3.664e-272 864.0
HKD3_k127_4839748_1 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000006757 163.0
HKD3_k127_4839748_2 Histone deacetylase domain - - - 0.0000000000006966 81.0
HKD3_k127_4849558_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 449.0
HKD3_k127_4849558_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 362.0
HKD3_k127_4849558_2 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000001172 216.0
HKD3_k127_4849558_3 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000001289 196.0
HKD3_k127_4851001_0 Ferritin, Dps family protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000006129 261.0
HKD3_k127_4851001_1 membrane - GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0043021,GO:0043024,GO:0044464,GO:0044877,GO:0060187,GO:0071944 - 0.000000000003078 76.0
HKD3_k127_4859764_0 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000003441 211.0
HKD3_k127_4859764_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000007167 65.0
HKD3_k127_487277_0 AcrB/AcrD/AcrF family - - - 0.0 1587.0
HKD3_k127_487277_1 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 463.0
HKD3_k127_487277_10 - - - - 0.000000000000000000000000000000000000000000002968 183.0
HKD3_k127_487277_11 PFAM Transcriptional regulator, TetR-like, DNA-binding, bacterial archaeal - - - 0.000000000000000000000000000000000000005337 156.0
HKD3_k127_487277_12 PFAM cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.0000000000000000000000000000003198 130.0
HKD3_k127_487277_13 TIGRFAM outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000001658 110.0
HKD3_k127_487277_14 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000002538 104.0
HKD3_k127_487277_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 445.0
HKD3_k127_487277_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 381.0
HKD3_k127_487277_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 315.0
HKD3_k127_487277_5 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008945 264.0
HKD3_k127_487277_6 esterase lipase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000009227 260.0
HKD3_k127_487277_7 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000006539 210.0
HKD3_k127_487277_8 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000000000000000000169 195.0
HKD3_k127_487277_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000000002482 188.0
HKD3_k127_4882673_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 410.0
HKD3_k127_4882673_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 334.0
HKD3_k127_4882673_2 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 327.0
HKD3_k127_4882673_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 300.0
HKD3_k127_4882673_4 Kelch motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000002709 254.0
HKD3_k127_4882673_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K01317 - 3.4.21.10 0.000000000000000000000000000000000000000000000000000000000000000001101 249.0
HKD3_k127_4882673_6 2OG-Fe(II) oxygenase superfamily - - - 0.00000000000000000000000000000000000000000000008591 175.0
HKD3_k127_4882673_7 chain release factor K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000000000000000000007117 160.0
HKD3_k127_4882673_8 transglycosylase - - - 0.0000000000003606 74.0
HKD3_k127_4888815_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 4.208e-197 625.0
HKD3_k127_4888815_1 Glycosyl transferases group 1 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 586.0
HKD3_k127_4888815_2 UDP binding domain K00066 - 1.1.1.132 0.0000000000000000000000000000000008819 138.0
HKD3_k127_4893112_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 1.233e-261 821.0
HKD3_k127_4893112_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 368.0
HKD3_k127_4893112_2 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 318.0
HKD3_k127_4893112_3 Autotransporter beta-domain K12686 - - 0.0000000000000000000000000000000000000000000000000002781 200.0
HKD3_k127_4893112_4 PFAM Cyclic nucleotide-binding K21563 - - 0.00000000000000000000000000000000000000000000000004709 187.0
HKD3_k127_4893112_5 - - - - 0.0000000000000000000000000000000000000004612 156.0
HKD3_k127_4893112_6 transcriptional - - - 0.0000000000000000000000000002765 131.0
HKD3_k127_4899499_0 Belongs to the glycosyl hydrolase 31 family K01811 GO:0003674,GO:0003824,GO:0004553,GO:0005488,GO:0005515,GO:0016787,GO:0016798,GO:0042802,GO:0080176 3.2.1.177 1.506e-208 672.0
HKD3_k127_4899499_1 Catalyzes the conversion of L-arabinose to L-ribulose - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 589.0
HKD3_k127_4899499_2 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 356.0
HKD3_k127_4899499_3 Belongs to the HpcH HpaI aldolase family K01630 - 4.1.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 323.0
HKD3_k127_4899499_4 Transaldolase/Fructose-6-phosphate aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 299.0
HKD3_k127_4899499_5 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 316.0
HKD3_k127_4899499_6 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004134 264.0
HKD3_k127_4899499_7 Aldose 1-epimerase K01785 - 5.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000007627 229.0
HKD3_k127_4899499_8 Domain of unknown function (DUF4867) - - - 0.0000000000000000000000000000000000000000000000000000002603 211.0
HKD3_k127_4900085_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1033.0
HKD3_k127_4900085_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 372.0
HKD3_k127_4900085_2 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000005054 200.0
HKD3_k127_4900085_3 Putative metallopeptidase domain - - - 0.0000000000000000000000000000002958 126.0
HKD3_k127_4900085_4 Hsp20/alpha crystallin family - - - 0.000000000000000000002434 104.0
HKD3_k127_4900085_5 - - - - 0.00000000000009381 78.0
HKD3_k127_4911980_0 Prolyl oligopeptidase family - - - 3.966e-196 633.0
HKD3_k127_4911980_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 544.0
HKD3_k127_4911980_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 519.0
HKD3_k127_4911980_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000008144 261.0
HKD3_k127_4911980_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.000000000000000000000000000000000000000000000000000000001368 211.0
HKD3_k127_4911980_5 KTSC domain - - - 0.000000000000000000003174 94.0
HKD3_k127_4911980_6 Thioredoxin-like - - - 0.0000000000000008895 83.0
HKD3_k127_4911980_7 dksA traR - - - 0.000000000000003028 81.0
HKD3_k127_4911980_8 Yip1 domain - - - 0.00000002233 64.0
HKD3_k127_4911980_9 Periplasmic Protein K08985 - - 0.0004734 47.0
HKD3_k127_4927314_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 454.0
HKD3_k127_4927314_1 Urea ABC transporter ATP-binding protein urtd K11962 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 434.0
HKD3_k127_4927314_2 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 376.0
HKD3_k127_4927314_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 352.0
HKD3_k127_4927314_4 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000000000001031 180.0
HKD3_k127_4927314_5 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000006816 179.0
HKD3_k127_4927538_0 glycosyl transferase K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000003342 240.0
HKD3_k127_4927538_1 Nad-dependent epimerase dehydratase K00091,K01784 - 1.1.1.219,5.1.3.2 0.0000000000000000000000000000000000006685 158.0
HKD3_k127_4931114_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 379.0
HKD3_k127_4931114_1 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
HKD3_k127_4931114_2 SCO1/SenC K07152 - - 0.000000000000000000000000000000000225 140.0
HKD3_k127_4931114_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0002559 46.0
HKD3_k127_49313_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 323.0
HKD3_k127_49313_1 coenzyme F420 binding K07226 - - 0.000000000000000000000000001496 123.0
HKD3_k127_49313_2 - - - - 0.000000000000000000000003372 115.0
HKD3_k127_4934242_0 Cysteine-rich domain - - - 8.459e-211 664.0
HKD3_k127_4934242_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 494.0
HKD3_k127_4934242_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 394.0
HKD3_k127_4934242_3 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001012 248.0
HKD3_k127_4934242_4 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000113 258.0
HKD3_k127_4934242_5 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000006794 252.0
HKD3_k127_4934242_6 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000000001902 175.0
HKD3_k127_4945187_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001924 269.0
HKD3_k127_4945187_1 Protein of unknown function (DUF1838) - - - 0.0000000000000000000000000000000000000000000000000000000000672 213.0
HKD3_k127_4955764_0 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 376.0
HKD3_k127_4955764_1 LysR substrate binding domain K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 363.0
HKD3_k127_4955764_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001138 248.0
HKD3_k127_4955764_3 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000002473 172.0
HKD3_k127_4988169_0 UDP binding domain K00066 - 1.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 558.0
HKD3_k127_4988169_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000008208 210.0
HKD3_k127_4988169_2 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000002462 150.0
HKD3_k127_501154_0 ATP-dependent helicase hrpA K03578 - 3.6.4.13 0.0 1232.0
HKD3_k127_501154_1 Protein of unknown function (DUF1631) - - - 0.00000000000000000000000000000000000000000000000000000000000000002612 245.0
HKD3_k127_5024504_0 ERAP1-like C-terminal domain K01256 - 3.4.11.2 5.991e-212 689.0
HKD3_k127_5024504_1 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 595.0
HKD3_k127_5024504_10 - - - - 0.0000000000000000000000000000000000000000001808 180.0
HKD3_k127_5024504_11 helix_turn _helix lactose operon repressor K06145 - - 0.00000000000000000000000000000008967 136.0
HKD3_k127_5024504_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 610.0
HKD3_k127_5024504_3 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 301.0
HKD3_k127_5024504_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000802 274.0
HKD3_k127_5024504_5 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000001931 261.0
HKD3_k127_5024504_6 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000002214 224.0
HKD3_k127_5024504_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000007231 211.0
HKD3_k127_5024504_8 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000001556 195.0
HKD3_k127_5024504_9 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000002466 195.0
HKD3_k127_5024808_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1247.0
HKD3_k127_5024808_1 PQQ enzyme repeat - - - 1.183e-302 940.0
HKD3_k127_5024808_10 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000003432 164.0
HKD3_k127_5024808_11 TonB dependent receptor K02014 - - 0.0000000000000004111 79.0
HKD3_k127_5024808_2 Protein tyrosine kinase K12132 - 2.7.11.1 1.094e-207 676.0
HKD3_k127_5024808_3 ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 436.0
HKD3_k127_5024808_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 338.0
HKD3_k127_5024808_5 Dehydrogenase K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 333.0
HKD3_k127_5024808_6 carbon monoxide dehydrogenase K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002785 245.0
HKD3_k127_5024808_7 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000003433 252.0
HKD3_k127_5024808_8 - - - - 0.000000000000000000000000000000000000000000000007005 193.0
HKD3_k127_5024808_9 Ankyrin repeats (3 copies) K06867 - - 0.00000000000000000000000000000000000000000000006384 178.0
HKD3_k127_5025964_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 352.0
HKD3_k127_5025964_1 Glycosyltransferase like family - - - 0.0000000000000000000000000000000000000004406 166.0
HKD3_k127_5025964_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000001504 158.0
HKD3_k127_5025964_3 Glycosyl transferase, family 2 K20444 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000004939 162.0
HKD3_k127_5025964_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000257 50.0
HKD3_k127_5034892_0 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 528.0
HKD3_k127_5034892_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 380.0
HKD3_k127_5034892_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002456 243.0
HKD3_k127_5034892_3 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000003723 186.0
HKD3_k127_5043464_0 tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 5.715e-200 633.0
HKD3_k127_5043464_1 Fumarylacetoacetate (FAA) hydrolase family K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 464.0
HKD3_k127_5043464_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006363 261.0
HKD3_k127_5043464_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000007598 119.0
HKD3_k127_5043464_5 NADP oxidoreductase coenzyme F420-dependent - - - 0.000000000000000008861 84.0
HKD3_k127_505539_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 546.0
HKD3_k127_505539_1 phosphate K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 439.0
HKD3_k127_505539_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000002001 244.0
HKD3_k127_505928_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 3.192e-297 945.0
HKD3_k127_505928_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 506.0
HKD3_k127_505928_2 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000001417 252.0
HKD3_k127_505928_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000003772 209.0
HKD3_k127_505928_4 arylamine N-acetyltransferase activity K00675 - 2.3.1.118 0.0000000000000000000000000000000000000000000000000000000001933 220.0
HKD3_k127_5060320_0 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 329.0
HKD3_k127_5060320_1 Methyltransferase domain - - - 0.0000000000000000000000001298 114.0
HKD3_k127_5060872_0 ATPases associated with a variety of cellular activities K05779 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001029 280.0
HKD3_k127_5060872_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003004 274.0
HKD3_k127_5060872_2 transport system, permease component K05778 - - 0.000000000000000000000000000000000000000007294 156.0
HKD3_k127_5060872_3 PAS domain - - - 0.00000000000000000000000001808 115.0
HKD3_k127_5066076_0 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 457.0
HKD3_k127_5066076_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 427.0
HKD3_k127_5085639_0 DoxX-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 485.0
HKD3_k127_5085639_1 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 260.0
HKD3_k127_5085639_2 Predicted integral membrane protein (DUF2269) - - - 0.0000000000000000000000000000000000000000000000000000000001691 228.0
HKD3_k127_5085639_3 - - - - 0.000000000000000000000000000000000000000002152 176.0
HKD3_k127_5085639_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000001119 160.0
HKD3_k127_5085639_5 - - - - 0.0000000000000000000000000000000000004392 154.0
HKD3_k127_5086832_0 ABC transporter transmembrane region K06147,K18893 - - 3.285e-305 947.0
HKD3_k127_5086832_1 Glycosyltransferase like family 2 - - - 8.21e-265 828.0
HKD3_k127_5086832_10 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 346.0
HKD3_k127_5086832_11 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 340.0
HKD3_k127_5086832_12 Ornithine cyclodeaminase/mu-crystallin family K01750,K19743 - 1.5.1.1,4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 314.0
HKD3_k127_5086832_13 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002396 274.0
HKD3_k127_5086832_14 HutD K09975 - - 0.000000000000000000000000009513 121.0
HKD3_k127_5086832_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 3.369e-222 698.0
HKD3_k127_5086832_3 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 536.0
HKD3_k127_5086832_4 Amidohydrolase family K05603 - 3.5.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 516.0
HKD3_k127_5086832_5 fad dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 492.0
HKD3_k127_5086832_6 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 465.0
HKD3_k127_5086832_7 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 398.0
HKD3_k127_5086832_8 Protein of unknown function (DUF4254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 364.0
HKD3_k127_5086832_9 Subtilase family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 348.0
HKD3_k127_5104212_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1125.0
HKD3_k127_5104212_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 6.817e-279 865.0
HKD3_k127_5104212_10 methyltransferase K03437 - - 0.00000000000000000000000000000000000000000000000000000003999 205.0
HKD3_k127_5104212_11 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000000004907 160.0
HKD3_k127_5104212_12 RbsD / FucU transport protein family K02431 - 5.1.3.29 0.0000000000000000000000000000000006604 136.0
HKD3_k127_5104212_13 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000008748 112.0
HKD3_k127_5104212_14 - - - - 0.000000002715 58.0
HKD3_k127_5104212_15 - - - - 0.00000005565 55.0
HKD3_k127_5104212_16 Belongs to the peptidase S1B family - - - 0.0000002929 64.0
HKD3_k127_5104212_17 - - - - 0.0001739 50.0
HKD3_k127_5104212_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 8.571e-220 695.0
HKD3_k127_5104212_3 Putative amidoligase enzyme (DUF2126) - - - 9.374e-204 638.0
HKD3_k127_5104212_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 609.0
HKD3_k127_5104212_5 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 448.0
HKD3_k127_5104212_6 DNA polymerase alpha chain like domain K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 328.0
HKD3_k127_5104212_7 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 305.0
HKD3_k127_5104212_8 Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000005934 224.0
HKD3_k127_5104212_9 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.000000000000000000000000000000000000000000000000000000000001522 234.0
HKD3_k127_5110181_0 2-methylcitrate dehydratase K01720 - 4.2.1.79 2.521e-260 810.0
HKD3_k127_5110181_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 1.792e-215 672.0
HKD3_k127_5110181_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 558.0
HKD3_k127_5110181_3 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 533.0
HKD3_k127_5110181_4 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 463.0
HKD3_k127_5110181_5 GntR family K03710 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 287.0
HKD3_k127_5110181_6 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000000000000004934 142.0
HKD3_k127_5110181_7 succinate dehydrogenase, cytochrome b subunit K00241 - - 0.00000000000000000000000000001359 121.0
HKD3_k127_5110181_8 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000232 86.0
HKD3_k127_5111387_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 373.0
HKD3_k127_5111387_1 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002082 263.0
HKD3_k127_5111387_2 O-methyltransferase activity - - - 0.00000000000000000000000000000001432 129.0
HKD3_k127_5118036_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1328.0
HKD3_k127_5118036_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 551.0
HKD3_k127_5118036_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 443.0
HKD3_k127_5118036_3 Belongs to the PdxA family K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 377.0
HKD3_k127_5118036_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 304.0
HKD3_k127_5118036_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
HKD3_k127_5118036_6 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000002243 198.0
HKD3_k127_5118036_7 CRS1_YhbY K07574 - - 0.0000000000000000000000001438 117.0
HKD3_k127_5122912_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 6.046e-233 759.0
HKD3_k127_5122912_1 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 424.0
HKD3_k127_5122912_2 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 321.0
HKD3_k127_5122912_3 response regulator K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 288.0
HKD3_k127_5122912_4 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002551 255.0
HKD3_k127_5122912_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000435 230.0
HKD3_k127_5122912_6 Acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000002003 201.0
HKD3_k127_5122912_7 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000776 136.0
HKD3_k127_5127141_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 493.0
HKD3_k127_5127141_1 FtsK SpoIIIE family protein K03466 - - 0.00000000000000000000000000000000000000000000000000004888 213.0
HKD3_k127_5127141_2 Smr domain - - - 0.0000000000000000000000000000000000000001128 160.0
HKD3_k127_5186501_0 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 387.0
HKD3_k127_5186501_1 SAM (And some other nucleotide) binding motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004872 248.0
HKD3_k127_5186501_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000005283 224.0
HKD3_k127_5186501_3 Protein of unknown function (DUF2721) - - - 0.000000000000000000005864 107.0
HKD3_k127_5257990_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007358 248.0
HKD3_k127_5257990_1 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000002075 200.0
HKD3_k127_5257990_2 Protein of unknown function (DUF3106) - - - 0.00000000000000000000008335 111.0
HKD3_k127_5257990_3 RDD family - - - 0.0000000000000001546 92.0
HKD3_k127_5257990_5 Transposase IS200 like K07491 - - 0.000004044 55.0
HKD3_k127_5257990_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00003042 50.0
HKD3_k127_5258374_0 Belongs to the peptidase M16 family K07263 - - 1.286e-276 889.0
HKD3_k127_5258374_1 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 461.0
HKD3_k127_5258374_2 Methylmalonyl-CoA mutase K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.000000000000000000000000000000000000000000000000000000000000000000000003396 264.0
HKD3_k127_5258374_3 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000128 144.0
HKD3_k127_5258374_4 Peptidase family M48 - - - 0.00000000000000000000000000005687 129.0
HKD3_k127_5258374_5 Bacterial SH3 domain - - - 0.00000000000000974 83.0
HKD3_k127_5263922_0 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001284 261.0
HKD3_k127_5263922_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000004449 257.0
HKD3_k127_5263922_2 YGGT family - - - 0.00000000000000000000000000000000006676 143.0
HKD3_k127_5263922_3 twitching motility protein K02669 - - 0.000000000000000000000000000000004005 128.0
HKD3_k127_5263922_4 DUF167 K09131 - - 0.000000000000000000000005013 113.0
HKD3_k127_5268776_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.025e-283 892.0
HKD3_k127_5268776_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 401.0
HKD3_k127_5268776_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 334.0
HKD3_k127_5268776_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 304.0
HKD3_k127_5268776_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000003776 244.0
HKD3_k127_5268776_5 Von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000001707 213.0
HKD3_k127_5268776_6 Peptidase family M50 K11749 - - 0.000000000000000000000000000000000000000000000000000000000001028 213.0
HKD3_k127_5268776_7 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000001089 194.0
HKD3_k127_5268776_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000008964 147.0
HKD3_k127_5275019_0 Transglycosylase SLT domain - - - 3.618e-197 648.0
HKD3_k127_5275019_1 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 610.0
HKD3_k127_5275019_2 Belongs to the LDH2 MDH2 oxidoreductase family K00073 - 1.1.1.350 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 347.0
HKD3_k127_5275019_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000237 280.0
HKD3_k127_5275019_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000162 149.0
HKD3_k127_5306132_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 GO:0003674,GO:0003824,GO:0003942,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 494.0
HKD3_k127_5306132_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006042 250.0
HKD3_k127_5306132_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000001986 217.0
HKD3_k127_5306132_3 redox protein regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000001181 184.0
HKD3_k127_5306132_4 Copper chaperone PCu(A)C K09796 - - 0.00000000008379 67.0
HKD3_k127_5313492_0 binding-protein-dependent transport systems inner membrane component K02011 - - 2.369e-257 818.0
HKD3_k127_5313492_1 COG1960 Acyl-CoA dehydrogenases K20035 - - 4.51e-238 750.0
HKD3_k127_5313492_10 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 359.0
HKD3_k127_5313492_11 response regulator receiver K10715,K20974 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 362.0
HKD3_k127_5313492_12 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 295.0
HKD3_k127_5313492_13 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002157 248.0
HKD3_k127_5313492_14 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000006771 221.0
HKD3_k127_5313492_15 Enoyl-CoA hydratase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000004261 222.0
HKD3_k127_5313492_16 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000001547 203.0
HKD3_k127_5313492_17 - - - - 0.0000000000000000000000000000000000000000000000008594 194.0
HKD3_k127_5313492_18 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000323 194.0
HKD3_k127_5313492_19 - - - - 0.000000000000000000000000000000003062 147.0
HKD3_k127_5313492_2 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 604.0
HKD3_k127_5313492_20 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000007968 130.0
HKD3_k127_5313492_21 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.0000000000000000000001958 113.0
HKD3_k127_5313492_22 - - - - 0.00000000000000001001 90.0
HKD3_k127_5313492_24 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0005322 47.0
HKD3_k127_5313492_3 extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 441.0
HKD3_k127_5313492_4 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 430.0
HKD3_k127_5313492_5 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 415.0
HKD3_k127_5313492_6 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 391.0
HKD3_k127_5313492_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 400.0
HKD3_k127_5313492_8 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 402.0
HKD3_k127_5313492_9 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 376.0
HKD3_k127_5378261_0 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 492.0
HKD3_k127_5378261_1 ABC-type sugar K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 382.0
HKD3_k127_5378261_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000005333 262.0
HKD3_k127_5378261_3 Glutaredoxin K07390 - - 0.0000000000000000000000000000000000000000001211 163.0
HKD3_k127_5486834_0 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 4.915e-224 704.0
HKD3_k127_5486834_1 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 2.448e-201 640.0
HKD3_k127_5486834_10 Glutathione peroxidase K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000005246 228.0
HKD3_k127_5486834_11 Protein of unknown function (DUF3833) - - - 0.000000000000000000000000000000000000000000000000009551 203.0
HKD3_k127_5486834_12 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000006038 175.0
HKD3_k127_5486834_13 PGAP1-like protein - - - 0.0000000000000000000000000000000000001739 159.0
HKD3_k127_5486834_14 Chalcone isomerase-like - - - 0.00000000000000000000000000000000008243 144.0
HKD3_k127_5486834_2 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 501.0
HKD3_k127_5486834_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 463.0
HKD3_k127_5486834_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009816 430.0
HKD3_k127_5486834_5 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004483 375.0
HKD3_k127_5486834_6 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 351.0
HKD3_k127_5486834_7 B12 binding domain K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 314.0
HKD3_k127_5486834_8 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 289.0
HKD3_k127_5486834_9 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000003914 236.0
HKD3_k127_548745_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 459.0
HKD3_k127_548745_1 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 320.0
HKD3_k127_548745_2 Protein of unknown function (DUF2877) - - - 0.0000000000000000000000000000000000001656 153.0
HKD3_k127_548745_3 Protein of unknown function (DUF1116) K02381 - - 0.000000000000000000000000007485 111.0
HKD3_k127_548745_4 Pfam:Ureidogly_hydro K01483 - 4.3.2.3 0.000000000000000000000001991 119.0
HKD3_k127_550456_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 347.0
HKD3_k127_550456_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 303.0
HKD3_k127_550456_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000009167 134.0
HKD3_k127_55368_0 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1148.0
HKD3_k127_55368_1 MacB-like periplasmic core domain K02004 - - 2.369e-237 775.0
HKD3_k127_55368_10 Putative metallopeptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000002082 217.0
HKD3_k127_55368_11 Protein of unknown function (DUF2905) - - - 0.00000000000000000000006465 103.0
HKD3_k127_55368_2 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007988 571.0
HKD3_k127_55368_3 PFAM ATPase associated with various cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 443.0
HKD3_k127_55368_4 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 409.0
HKD3_k127_55368_5 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 317.0
HKD3_k127_55368_6 HlyD family secretion protein K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 304.0
HKD3_k127_55368_7 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 268.0
HKD3_k127_55368_8 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004318 261.0
HKD3_k127_55368_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000114 231.0
HKD3_k127_5572751_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 1.725e-221 697.0
HKD3_k127_5572751_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 3.421e-203 651.0
HKD3_k127_5572751_10 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000004029 178.0
HKD3_k127_5572751_11 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000002338 85.0
HKD3_k127_5572751_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 573.0
HKD3_k127_5572751_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 486.0
HKD3_k127_5572751_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 422.0
HKD3_k127_5572751_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 453.0
HKD3_k127_5572751_6 Surface antigen K07278 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 352.0
HKD3_k127_5572751_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 328.0
HKD3_k127_5572751_8 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000005477 228.0
HKD3_k127_5572751_9 - - - - 0.000000000000000000000000000000000000000000000000000000139 209.0
HKD3_k127_568279_0 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 364.0
HKD3_k127_568279_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 332.0
HKD3_k127_568279_2 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000002669 255.0
HKD3_k127_568279_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000001962 224.0
HKD3_k127_568279_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000001567 192.0
HKD3_k127_5690971_0 phenylacetic acid degradation protein paaN - - - 3.514e-199 627.0
HKD3_k127_5690971_1 Phenylacetic acid catabolic protein K02609 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 580.0
HKD3_k127_5690971_2 Oxidoreductase FAD-binding domain K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 479.0
HKD3_k127_5690971_3 phenylacetic acid K02611 - 1.14.13.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009955 342.0
HKD3_k127_5690971_4 phenylacetate-CoA oxygenase, PaaJ subunit K02612 GO:0006082,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016054,GO:0019439,GO:0019748,GO:0019752,GO:0032787,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000001737 211.0
HKD3_k127_5690971_5 PaaX-like protein K02616 - - 0.00000000000000000000000000000000000000000000000000000002227 205.0
HKD3_k127_5690971_6 Phenylacetic acid degradation B K02610 - - 0.0000000000000000000000000000000000000000000000000003464 186.0
HKD3_k127_5710640_0 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005523 522.0
HKD3_k127_5710640_1 helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 348.0
HKD3_k127_5710640_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000002623 94.0
HKD3_k127_5710645_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 3.965e-215 677.0
HKD3_k127_5710645_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 344.0
HKD3_k127_5710645_2 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000000000002136 210.0
HKD3_k127_5710645_3 import inner membrane translocase subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000009747 188.0
HKD3_k127_5710645_4 twitching motility protein K02670 - - 0.00000000000000000000000000000000004844 135.0
HKD3_k127_5710645_5 SCP-2 sterol transfer family K03690 - - 0.0000000381 66.0
HKD3_k127_572768_0 Berberine and berberine like - - - 6.313e-203 644.0
HKD3_k127_572768_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 344.0
HKD3_k127_572768_2 Histidine kinase K20975 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 337.0
HKD3_k127_572768_3 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000003467 238.0
HKD3_k127_572768_4 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000000000003037 201.0
HKD3_k127_572768_5 Outer membrane lipoprotein K06077 - - 0.00000000000000000000000000000000000000000005788 177.0
HKD3_k127_572768_6 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000004205 166.0
HKD3_k127_572768_9 Heavy-metal resistance - - - 0.00000003348 63.0
HKD3_k127_5771715_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 529.0
HKD3_k127_5771715_1 hydrolases of the HAD superfamily - - - 0.000000000000000000000000000000000000000001306 158.0
HKD3_k127_5771715_2 Phosphotransferase enzyme family - - - 0.000000000007779 66.0
HKD3_k127_5781856_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 386.0
HKD3_k127_5781856_1 PFAM multicopper oxidase type K04753,K08100,K14588 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 365.0
HKD3_k127_5781856_2 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 317.0
HKD3_k127_5781856_3 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003556 278.0
HKD3_k127_5781856_4 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000002292 257.0
HKD3_k127_5781856_5 Protein of unknown function (DUF3011) - - - 0.0000000000000000000000000000000000000000007456 166.0
HKD3_k127_5781856_6 Protein of unknown function (DUF3011) - - - 0.000000000000000000000000000000000000000006553 168.0
HKD3_k127_5781856_7 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.000000000000000000000682 96.0
HKD3_k127_580085_0 PFAM Type II secretion system protein E K02454 - - 2.311e-211 672.0
HKD3_k127_580085_1 Type II secretion system K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 383.0
HKD3_k127_580085_2 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000000000000000000008631 173.0
HKD3_k127_580085_3 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000389 163.0
HKD3_k127_580085_4 fimbrial assembly K02461 - - 0.000000000000000000000000000000000006976 155.0
HKD3_k127_580085_5 General secretion pathway protein H K02457 - - 0.00000000000000000000000000000001571 132.0
HKD3_k127_580085_6 General secretion pathway protein K02459 - - 0.0000000000000000000000585 112.0
HKD3_k127_580085_7 Prokaryotic N-terminal methylation motif - - - 0.00000000001161 77.0
HKD3_k127_580085_8 General secretion pathway protein M K02462 - - 0.00004497 55.0
HKD3_k127_581706_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 479.0
HKD3_k127_581706_1 Efflux pump membrane transporter K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002056 273.0
HKD3_k127_581706_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001529 292.0
HKD3_k127_5832772_0 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 509.0
HKD3_k127_5832772_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 356.0
HKD3_k127_5832772_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006673 263.0
HKD3_k127_5878352_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007126 442.0
HKD3_k127_5878352_1 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.000000000000000000000000000000000000001616 154.0
HKD3_k127_5878352_2 YXWGXW repeat (2 copies) - - - 0.000000000000000000000003588 111.0
HKD3_k127_5878352_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000001536 96.0
HKD3_k127_5878352_4 Pfam Response regulator receiver - - - 0.000000001272 67.0
HKD3_k127_5878352_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0001071 44.0
HKD3_k127_5878585_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.025e-215 679.0
HKD3_k127_5878585_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 296.0
HKD3_k127_5886192_0 PFAM Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 351.0
HKD3_k127_5886192_1 NnrU protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001607 243.0
HKD3_k127_5886192_2 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000008728 198.0
HKD3_k127_5886192_3 Protein of unknown function (DUF3014) - - - 0.00000000000000000000000000000000000000000000000000000104 203.0
HKD3_k127_5886192_4 Cytochrome c K17223 - - 0.00000000000000000004788 104.0
HKD3_k127_5951191_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000001038 132.0
HKD3_k127_5951191_1 Belongs to the UPF0337 (CsbD) family - - - 0.00000000000000000000000008212 113.0
HKD3_k127_6034978_0 Required for chromosome condensation and partitioning K03529 - - 4.844e-296 947.0
HKD3_k127_6034978_1 breast cancer carboxy-terminal domain K01972 - 6.5.1.2 2.27e-279 895.0
HKD3_k127_6034978_2 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000132 187.0
HKD3_k127_6034978_3 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000001954 123.0
HKD3_k127_6054555_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 3.403e-202 645.0
HKD3_k127_6054555_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000002483 199.0
HKD3_k127_6054555_2 - - - - 0.000000003201 64.0
HKD3_k127_6057612_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 574.0
HKD3_k127_6057612_1 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 479.0
HKD3_k127_6057612_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000002378 220.0
HKD3_k127_6057612_3 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000000000000006108 116.0
HKD3_k127_6058238_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 290.0
HKD3_k127_6058238_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003062 267.0
HKD3_k127_6058238_2 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000006202 75.0
HKD3_k127_6059873_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.563e-227 728.0
HKD3_k127_6059873_1 DNA mismatch repair protein, C-terminal domain K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 625.0
HKD3_k127_6059873_10 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000005119 243.0
HKD3_k127_6059873_11 Glutamine amidotransferase class-I - - - 0.000000000000000000000000000000000000000000000000000000000000000003552 233.0
HKD3_k127_6059873_12 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000001261 205.0
HKD3_k127_6059873_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 546.0
HKD3_k127_6059873_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 518.0
HKD3_k127_6059873_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 520.0
HKD3_k127_6059873_5 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000079 426.0
HKD3_k127_6059873_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 365.0
HKD3_k127_6059873_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 329.0
HKD3_k127_6059873_8 IPP transferase K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 331.0
HKD3_k127_6059873_9 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 292.0
HKD3_k127_6060013_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000009598 129.0
HKD3_k127_6060013_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000001946 119.0
HKD3_k127_6060013_2 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000009668 79.0
HKD3_k127_6060013_3 Sigma factor PP2C-like phosphatases - - - 0.000001784 61.0
HKD3_k127_6060458_0 asparaginyl-tRNA synthetase K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 452.0
HKD3_k127_6060458_1 C-terminal, D2-small domain, of ClpB protein K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 433.0
HKD3_k127_6060458_11 VanZ like family - - - 0.0000000000000000000006078 100.0
HKD3_k127_6060458_2 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 322.0
HKD3_k127_6060458_3 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 340.0
HKD3_k127_6060458_4 Glutathione S-transferase, C-terminal domain K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 312.0
HKD3_k127_6060458_5 Lytic transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001533 268.0
HKD3_k127_6060458_6 Hydrogenase urease accessory protein K03192 - - 0.000000000000000000000000000000000000000000000000000000000000000000001265 257.0
HKD3_k127_6060458_7 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002505 234.0
HKD3_k127_6060458_8 cobalamin-transporting ATPase activity - - - 0.000000000000000000000000000000112 138.0
HKD3_k127_6060458_9 Family of unknown function (DUF5329) - - - 0.00000000000000000000000000001648 127.0
HKD3_k127_606398_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 342.0
HKD3_k127_606398_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 288.0
HKD3_k127_606398_2 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000001303 245.0
HKD3_k127_606398_3 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000004704 192.0
HKD3_k127_606398_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000001126 195.0
HKD3_k127_606398_5 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000003075 124.0
HKD3_k127_6064061_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 430.0
HKD3_k127_6064061_1 Male sterility protein K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007487 406.0
HKD3_k127_6064061_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 392.0
HKD3_k127_6064061_3 - K01992 - - 0.00000000000000000000000000000000000000000000000000000003086 217.0
HKD3_k127_6064061_4 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000000001055 157.0
HKD3_k127_6064061_5 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000002582 128.0
HKD3_k127_6064061_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000002801 113.0
HKD3_k127_6064061_7 Thioredoxin-like - - - 0.0000000000000000000000006401 113.0
HKD3_k127_6064061_8 Rieske (2fe-2S) K00499 - 1.14.15.7 0.0000000000000001367 80.0
HKD3_k127_6072162_0 Threonine synthase K01733 - 4.2.3.1 1.008e-197 629.0
HKD3_k127_6072162_1 Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 601.0
HKD3_k127_6072162_10 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000126 205.0
HKD3_k127_6072162_11 Peptidase C13 family - - - 0.00000000000000000000000000000008131 141.0
HKD3_k127_6072162_12 - - - - 0.0000000000000000000000001156 115.0
HKD3_k127_6072162_13 - - - - 0.00000000493 62.0
HKD3_k127_6072162_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 548.0
HKD3_k127_6072162_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 483.0
HKD3_k127_6072162_4 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 468.0
HKD3_k127_6072162_5 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 382.0
HKD3_k127_6072162_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 381.0
HKD3_k127_6072162_7 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 301.0
HKD3_k127_6072162_8 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000002111 246.0
HKD3_k127_6072162_9 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000008146 247.0
HKD3_k127_6100918_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 499.0
HKD3_k127_6100918_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 406.0
HKD3_k127_6100918_2 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 294.0
HKD3_k127_6100918_3 Phosphotransferase system, mannose fructose-specific component IIA K02821 - 2.7.1.194 0.00000000000000000000000000000000000000001177 165.0
HKD3_k127_6100918_4 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000002438 136.0
HKD3_k127_6112401_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 6.92e-321 1004.0
HKD3_k127_6112401_1 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 354.0
HKD3_k127_6112401_10 Hemerythrin HHE cation binding domain - - - 0.0000000006143 66.0
HKD3_k127_6112401_2 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 358.0
HKD3_k127_6112401_3 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 335.0
HKD3_k127_6112401_4 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002164 261.0
HKD3_k127_6112401_5 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001879 247.0
HKD3_k127_6112401_6 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.000000000000000000000000000000000000000000000000000000000001675 228.0
HKD3_k127_6112401_7 DMSO reductase anchor subunit (DmsC) - - - 0.00000000000000000000000000000000000000001656 166.0
HKD3_k127_6112401_8 ferredoxin - - - 0.000000000000000000000000000000005715 141.0
HKD3_k127_6112401_9 4Fe-4S binding domain K18362 - - 0.000000000000000000001428 94.0
HKD3_k127_6112441_0 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 3.041e-291 904.0
HKD3_k127_6112441_1 glycosyl transferase family 2 K20444 - - 1.091e-247 808.0
HKD3_k127_6112441_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 421.0
HKD3_k127_6112441_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000834 320.0
HKD3_k127_6112441_4 Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002532 251.0
HKD3_k127_6112441_5 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000000005364 80.0
HKD3_k127_6112441_6 - - - - 0.0001009 55.0
HKD3_k127_6127514_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1184.0
HKD3_k127_6127514_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001833 271.0
HKD3_k127_613140_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 417.0
HKD3_k127_613140_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 385.0
HKD3_k127_613140_2 - - - - 0.00000000000000000000000000000000134 145.0
HKD3_k127_613140_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000001007 136.0
HKD3_k127_613140_4 - - - - 0.00000000000000000004038 101.0
HKD3_k127_613140_5 ATP synthase subunit C K02124 - - 0.0000000000000008723 91.0
HKD3_k127_613140_6 ATP synthase (F/14-kDa) subunit - - - 0.00000002557 59.0
HKD3_k127_6135944_0 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 578.0
HKD3_k127_6135944_1 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 501.0
HKD3_k127_6135944_2 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 470.0
HKD3_k127_6135944_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04101 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 404.0
HKD3_k127_6135944_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004467 244.0
HKD3_k127_6135944_5 Aromatic-ring-opening dioxygenase LigAB, LigA subunit K04100 - 1.13.11.8 0.00000000000000000000000000000000000000000000000000409 186.0
HKD3_k127_6135944_6 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 0.0000000000000000000000001694 105.0
HKD3_k127_6141844_0 Ureidoglycolate lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 372.0
HKD3_k127_6141844_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 361.0
HKD3_k127_6141844_10 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000003968 211.0
HKD3_k127_6141844_11 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000004444 194.0
HKD3_k127_6141844_12 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000006419 197.0
HKD3_k127_6141844_13 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000007982 190.0
HKD3_k127_6141844_14 - - - - 0.000000000000000000000000000000000000000000000000006677 190.0
HKD3_k127_6141844_15 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000002771 183.0
HKD3_k127_6141844_16 Belongs to the acetyltransferase family. ArgA subfamily K03830 - - 0.00000000000000000000000000000000000000000001033 170.0
HKD3_k127_6141844_17 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000000000000000000007006 159.0
HKD3_k127_6141844_18 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000000000000000002323 161.0
HKD3_k127_6141844_19 phosphatase (DUF442) - - - 0.0000000000000000000000000000000000000001691 160.0
HKD3_k127_6141844_2 Short-chain dehydrogenase reductase sdr K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000001713 267.0
HKD3_k127_6141844_20 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.000000000000000000000000000000000002294 139.0
HKD3_k127_6141844_21 - - - - 0.00000000000000000000000000000000001229 143.0
HKD3_k127_6141844_22 - - - - 0.0000000000000000000000000000000002061 149.0
HKD3_k127_6141844_23 - - - - 0.00000000000000000000000000005497 129.0
HKD3_k127_6141844_24 - - - - 0.000000000000000000000000000155 129.0
HKD3_k127_6141844_25 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000002242 110.0
HKD3_k127_6141844_28 Domain of unknown function (DU1801) - - - 0.000000000000003607 81.0
HKD3_k127_6141844_29 - - - - 0.00000000000003508 81.0
HKD3_k127_6141844_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006421 265.0
HKD3_k127_6141844_30 SnoaL-like domain - - - 0.00000000119 60.0
HKD3_k127_6141844_31 isochorismatase - - - 0.000000001545 66.0
HKD3_k127_6141844_32 Gnat family - - - 0.00000001317 64.0
HKD3_k127_6141844_33 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides K08281 - 3.5.1.19 0.00000005049 54.0
HKD3_k127_6141844_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006628 254.0
HKD3_k127_6141844_5 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007387 261.0
HKD3_k127_6141844_6 Activator of Hsp90 ATPase 1 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002428 257.0
HKD3_k127_6141844_7 FR47-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003258 259.0
HKD3_k127_6141844_8 AraC-like ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001257 244.0
HKD3_k127_6141844_9 PFAM Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004635 235.0
HKD3_k127_6149880_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 535.0
HKD3_k127_6149880_1 Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 446.0
HKD3_k127_6149880_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 328.0
HKD3_k127_6149880_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 331.0
HKD3_k127_6149880_4 UvrD REP K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000004437 194.0
HKD3_k127_6149880_5 - - - - 0.00000000000001726 83.0
HKD3_k127_6149880_6 Protein of unknown function (DUF2782) - - - 0.00000000000007477 83.0
HKD3_k127_6149880_7 -acetyltransferase - - - 0.0000000000001407 81.0
HKD3_k127_615032_0 dihydrolipoamide dehydrogenase (E3 component of pyruvate and 2-oxoglutarate dehydrogenase complexes) K00382 K00382 - 1.8.1.4 2.034e-271 867.0
HKD3_k127_615032_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 9.017e-214 679.0
HKD3_k127_615032_2 Thioredoxin - - - 0.0000000000000000000000000000000000000000000000000003043 189.0
HKD3_k127_6158945_0 alcohol dehydrogenase K13954 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 485.0
HKD3_k127_6158945_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003934 439.0
HKD3_k127_6158945_2 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 290.0
HKD3_k127_6158945_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009379 270.0
HKD3_k127_6158945_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000005329 206.0
HKD3_k127_6176538_0 Catalyzes the transformation of hydroxyatrazine to N-isopropylammelide and ethylamine in the atrazine degradation pathway K18456 - 3.5.4.32 9.244e-212 665.0
HKD3_k127_6176538_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 549.0
HKD3_k127_6177441_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008758 564.0
HKD3_k127_6177441_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 516.0
HKD3_k127_6177441_10 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000001643 125.0
HKD3_k127_6177441_11 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.0000000000000000000001226 110.0
HKD3_k127_6177441_12 peptidase S1 and S6 chymotrypsin Hap K01337 - 3.4.21.50 0.00006956 54.0
HKD3_k127_6177441_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 383.0
HKD3_k127_6177441_3 Membrane-bound lytic murein transglycosylase K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006741 369.0
HKD3_k127_6177441_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 358.0
HKD3_k127_6177441_5 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000009822 246.0
HKD3_k127_6177441_6 Protein of unknown function (DUF1345) - - - 0.000000000000000000000000000000000000000000000000000003675 202.0
HKD3_k127_6177441_7 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000000000003185 187.0
HKD3_k127_6177441_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000006184 174.0
HKD3_k127_6177441_9 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000000000000008598 142.0
HKD3_k127_6180557_0 PFAM aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 475.0
HKD3_k127_6180557_1 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 411.0
HKD3_k127_6180557_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002988 285.0
HKD3_k127_6180557_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000001432 188.0
HKD3_k127_6180557_4 aminopeptidase - - - 0.000000000000000000000000000000000000000000001892 187.0
HKD3_k127_6180557_5 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000001268 161.0
HKD3_k127_6181221_0 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 405.0
HKD3_k127_6181221_1 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 361.0
HKD3_k127_6181221_2 silverDB K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 310.0
HKD3_k127_6181221_3 plastoquinol--plastocyanin reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001884 242.0
HKD3_k127_6181221_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000002911 204.0
HKD3_k127_6181221_5 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000001536 119.0
HKD3_k127_6181221_6 PFAM Transglutaminase-like K22452 - 2.3.2.13 0.000000004156 69.0
HKD3_k127_6185215_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 544.0
HKD3_k127_6185215_1 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 523.0
HKD3_k127_6185215_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 331.0
HKD3_k127_6185215_3 hydrolases of the HAD superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009036 256.0
HKD3_k127_6185215_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000766 209.0
HKD3_k127_6188490_0 Oxidative deamination of D-amino acids K00285 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0008718,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019478,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046144,GO:0046395,GO:0046416,GO:0046436,GO:0055114,GO:0055130,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 610.0
HKD3_k127_6188490_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 541.0
HKD3_k127_6188490_2 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 404.0
HKD3_k127_6188490_3 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 349.0
HKD3_k127_6188490_4 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000937 270.0
HKD3_k127_6188490_5 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000001649 242.0
HKD3_k127_6190135_0 Molecular chaperone. Has ATPase activity K04079 - - 2.121e-257 809.0
HKD3_k127_6190135_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.001e-247 777.0
HKD3_k127_6190135_10 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000581 239.0
HKD3_k127_6190135_11 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000001276 193.0
HKD3_k127_6190135_12 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000481 197.0
HKD3_k127_6190135_13 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000009681 182.0
HKD3_k127_6190135_14 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000008608 169.0
HKD3_k127_6190135_15 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000005111 178.0
HKD3_k127_6190135_16 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000000000000000000000000000000000001899 168.0
HKD3_k127_6190135_17 Cytochrome c class I - - - 0.00000000000000000000000000000008238 128.0
HKD3_k127_6190135_18 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000001001 111.0
HKD3_k127_6190135_19 Cytochrome c, class I - - - 0.000000000000000000000001059 115.0
HKD3_k127_6190135_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 588.0
HKD3_k127_6190135_20 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000002431 98.0
HKD3_k127_6190135_21 Peptidase M48 - - - 0.00000000000000001856 98.0
HKD3_k127_6190135_22 - - - - 0.00000000000002654 79.0
HKD3_k127_6190135_23 His Kinase A (phosphoacceptor) domain - - - 0.000000000000256 77.0
HKD3_k127_6190135_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 598.0
HKD3_k127_6190135_4 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 446.0
HKD3_k127_6190135_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 407.0
HKD3_k127_6190135_6 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 339.0
HKD3_k127_6190135_7 cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004779 300.0
HKD3_k127_6190135_8 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001367 300.0
HKD3_k127_6190135_9 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001552 261.0
HKD3_k127_6196869_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 591.0
HKD3_k127_6197353_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.069e-240 766.0
HKD3_k127_6197353_1 amidohydrolase - - - 2.629e-207 663.0
HKD3_k127_6197353_2 Domain of unknown function DUF21 K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 581.0
HKD3_k127_6197353_3 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 400.0
HKD3_k127_6197353_4 Glycosyltransferase like family - - - 0.00000000000000000000000000000000000000000000000001924 192.0
HKD3_k127_6197353_5 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000003583 168.0
HKD3_k127_6197353_6 protein conserved in bacteria - - - 0.000000000000000000000000001804 116.0
HKD3_k127_6197353_8 Sel1 repeat - - - 0.0000000000295 75.0
HKD3_k127_6198798_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 4.173e-213 673.0
HKD3_k127_6198798_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 525.0
HKD3_k127_6198798_2 Male sterility protein K02473 - 5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 464.0
HKD3_k127_6198798_3 COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001573 267.0
HKD3_k127_6198798_4 DUF218 domain - - - 0.000000000000000000000000000000000000000000000000000000002576 208.0
HKD3_k127_6198798_5 Two component transcriptional regulator, LuxR family K13041 - - 0.0000000000000000000000000000000000000000000000000474 190.0
HKD3_k127_6198798_6 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.000000000000000000000000000000000000000000000001208 176.0
HKD3_k127_6198798_7 MASE1 - - - 0.000000000000000000000000000000000000000000001558 176.0
HKD3_k127_6204419_0 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 349.0
HKD3_k127_6204419_1 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001 261.0
HKD3_k127_6204419_2 dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000002956 216.0
HKD3_k127_6207767_0 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 3.138e-268 832.0
HKD3_k127_6207767_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 535.0
HKD3_k127_6207767_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 538.0
HKD3_k127_6207767_3 L-asparaginase II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 349.0
HKD3_k127_6207767_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009191 321.0
HKD3_k127_6207767_5 Sigma E regulatory protein, MucB RseB K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004764 255.0
HKD3_k127_6207767_6 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.000000000000000000000005416 109.0
HKD3_k127_6207767_7 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.000000000006167 70.0
HKD3_k127_6217518_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000782 545.0
HKD3_k127_6217518_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000009675 149.0
HKD3_k127_6226890_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 438.0
HKD3_k127_6226890_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 442.0
HKD3_k127_6226890_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 369.0
HKD3_k127_6226890_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000003593 235.0
HKD3_k127_6241413_0 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 395.0
HKD3_k127_6241413_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003751 282.0
HKD3_k127_6241413_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000001953 73.0
HKD3_k127_6247507_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 407.0
HKD3_k127_6247507_1 cobalamin biosynthetic process K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 327.0
HKD3_k127_6247507_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 325.0
HKD3_k127_6247507_3 (Lipo)protein K07287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 326.0
HKD3_k127_6247507_4 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006223 278.0
HKD3_k127_6247507_5 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000001495 207.0
HKD3_k127_6247507_6 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.000000000000000000000000000000000004313 143.0
HKD3_k127_6247507_7 - - - - 0.000000000000000000003223 101.0
HKD3_k127_6268049_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 298.0
HKD3_k127_6268049_1 type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000008592 229.0
HKD3_k127_6268049_2 Shikimate kinase K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000009962 187.0
HKD3_k127_6279507_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000000001643 211.0
HKD3_k127_6279507_1 PAS domain - - - 0.000000000000000000000000000000002009 148.0
HKD3_k127_6314749_0 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000001027 190.0
HKD3_k127_6314749_1 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01555 - 3.7.1.2 0.00000000000000001111 82.0
HKD3_k127_6314749_2 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.00000000000008787 81.0
HKD3_k127_6314749_3 Patatin phospholipase - - - 0.000001234 53.0
HKD3_k127_63159_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.078e-308 957.0
HKD3_k127_63159_1 Proton-conducting membrane transporter - - - 8.801e-275 860.0
HKD3_k127_63159_10 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000001017 243.0
HKD3_k127_63159_2 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 8.838e-245 763.0
HKD3_k127_63159_3 PFAM peptidase S10 serine carboxypeptidase - - - 6.691e-215 681.0
HKD3_k127_63159_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 588.0
HKD3_k127_63159_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 560.0
HKD3_k127_63159_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 580.0
HKD3_k127_63159_7 NADH dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 449.0
HKD3_k127_63159_8 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 310.0
HKD3_k127_63159_9 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 268.0
HKD3_k127_6352337_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 572.0
HKD3_k127_6352337_1 Histidine kinase - - - 0.0000000000000000000866 97.0
HKD3_k127_6369833_0 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 386.0
HKD3_k127_6369833_1 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001112 262.0
HKD3_k127_6369833_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000008755 113.0
HKD3_k127_6381816_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1596.0
HKD3_k127_6381816_1 CoA binding domain - - - 1.58e-271 855.0
HKD3_k127_6381816_2 Ribonucleotide reductase, barrel domain K00525 - 1.17.4.1 6.38e-201 641.0
HKD3_k127_6381816_3 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 485.0
HKD3_k127_6381816_4 Phenylacetic acid degradation protein PaaY K02617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 281.0
HKD3_k127_6381816_5 Thioesterase - - - 0.000000000000000000000000000000000000000000000000005629 206.0
HKD3_k127_6381816_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000184 182.0
HKD3_k127_6381816_7 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000002933 173.0
HKD3_k127_6401393_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 322.0
HKD3_k127_6401393_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 333.0
HKD3_k127_6401393_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 289.0
HKD3_k127_6403302_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 336.0
HKD3_k127_6403302_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001495 274.0
HKD3_k127_6403302_2 Cobalt uptake substrate-specific transmembrane region - - - 0.000000000000000000000000000000002695 136.0
HKD3_k127_6403302_3 Protein of unknown function (DUF2892) - - - 0.000000000000000000002426 94.0
HKD3_k127_6415222_0 Transposase for IS481 element - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 348.0
HKD3_k127_6415222_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000364 175.0
HKD3_k127_6415222_2 protein conserved in bacteria - - - 0.000000000000000000000000000001849 132.0
HKD3_k127_6415222_3 Fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.0000000000000000000001714 97.0
HKD3_k127_6418884_0 arylsulfatase A K01130 - 3.1.6.1 1.004e-257 822.0
HKD3_k127_6418884_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 5.665e-240 767.0
HKD3_k127_6418884_10 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 359.0
HKD3_k127_6418884_11 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 331.0
HKD3_k127_6418884_12 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 316.0
HKD3_k127_6418884_13 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 331.0
HKD3_k127_6418884_14 PFAM regulatory protein TetR K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001032 250.0
HKD3_k127_6418884_15 PFAM Glycosyl transferase family 4 K13007 - - 0.000000000000000000000000000000000000000000000000000001071 207.0
HKD3_k127_6418884_16 Bile acid - - - 0.000000000000000000000000000000000000000000000000000002978 202.0
HKD3_k127_6418884_17 Gram-negative porin - - - 0.0000000000000000000000000000000000000000000000000006159 199.0
HKD3_k127_6418884_18 Protein of unknown function (DUF4254) - - - 0.000000000000000000000000000000000000000000000000009965 201.0
HKD3_k127_6418884_19 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000001371 175.0
HKD3_k127_6418884_2 PFAM polysaccharide biosynthesis protein CapD - - - 2.775e-205 674.0
HKD3_k127_6418884_20 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000003824 164.0
HKD3_k127_6418884_21 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000008747 123.0
HKD3_k127_6418884_22 Belongs to the P(II) protein family K04752 - - 0.000000000000000000114 98.0
HKD3_k127_6418884_23 O-Antigen ligase - - - 0.0000000000000000001699 102.0
HKD3_k127_6418884_24 Domain of unknown function (DUF4864) - - - 0.0000000000000003438 93.0
HKD3_k127_6418884_25 WD repeat-containing protein - - - 0.0008026 49.0
HKD3_k127_6418884_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 540.0
HKD3_k127_6418884_4 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 441.0
HKD3_k127_6418884_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 442.0
HKD3_k127_6418884_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 426.0
HKD3_k127_6418884_7 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 373.0
HKD3_k127_6418884_8 glycosyl transferase group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 370.0
HKD3_k127_6418884_9 PGAP1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 348.0
HKD3_k127_6434944_0 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 480.0
HKD3_k127_6434944_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 416.0
HKD3_k127_6434944_2 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 311.0
HKD3_k127_6434944_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000001158 163.0
HKD3_k127_6442242_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 574.0
HKD3_k127_6442242_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006006 523.0
HKD3_k127_6442242_2 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008413 457.0
HKD3_k127_6580012_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 4.272e-232 759.0
HKD3_k127_6580012_1 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 405.0
HKD3_k127_6580012_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 344.0
HKD3_k127_6580012_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 340.0
HKD3_k127_6580012_4 Aldo/keto reductase family - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000001398 244.0
HKD3_k127_6580012_5 DnaJ molecular chaperone homology domain - - - 0.0000001036 60.0
HKD3_k127_6580012_6 - - - - 0.000488 48.0
HKD3_k127_6600886_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 291.0
HKD3_k127_6600886_1 LppC putative lipoprotein K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000002308 191.0
HKD3_k127_6600886_2 Stringent starvation protein B K03600 GO:0000502,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0009376,GO:0009893,GO:0009894,GO:0009896,GO:0010604,GO:0019222,GO:0019899,GO:0031597,GO:0032781,GO:0032991,GO:0042176,GO:0042802,GO:0042803,GO:0043085,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043462,GO:0044093,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0045732,GO:0046983,GO:0048518,GO:0050789,GO:0050790,GO:0051117,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0097159,GO:1901363,GO:1902494,GO:1904949,GO:1905368,GO:1905369,GO:1990904 - 0.000000000000000000000000000000000001391 145.0
HKD3_k127_6600886_3 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000638 118.0
HKD3_k127_6600886_4 - - - - 0.00000000000000000626 98.0
HKD3_k127_6600886_5 PFAM Glutathione S-transferase K03599 - - 0.000000003487 59.0
HKD3_k127_6607496_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 1.873e-204 643.0
HKD3_k127_6607496_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 520.0
HKD3_k127_6613675_0 (Lipo)protein K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000001434 181.0
HKD3_k127_6613675_1 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000003673 123.0
HKD3_k127_6613675_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.0004889 52.0
HKD3_k127_6693325_0 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 3.284e-205 649.0
HKD3_k127_6693325_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 407.0
HKD3_k127_6693325_2 alginate biosynthesis protein AlgZ FimS K08082 - 2.7.13.3 0.0000000000000000000000000000000000000001324 161.0
HKD3_k127_6693325_3 PQ loop repeat K15383 - - 0.0000000000001203 76.0
HKD3_k127_6737905_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.783e-234 736.0
HKD3_k127_6737905_1 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000004659 217.0
HKD3_k127_6737905_2 PFAM regulatory protein, MerR K22491 - - 0.0000000000000000000000000000000000000001075 164.0
HKD3_k127_6737905_3 - - - - 0.00000000000000000000000000000000002794 154.0
HKD3_k127_6737905_4 - - - - 0.0000000000002076 82.0
HKD3_k127_6791798_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 9.347e-309 965.0
HKD3_k127_6791798_1 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 4.53e-228 743.0
HKD3_k127_6791798_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.113e-196 625.0
HKD3_k127_6791798_3 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 581.0
HKD3_k127_6791798_4 Pyridine nucleotide-disulphide oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 573.0
HKD3_k127_6791798_5 Light harvesting pigment Major Facilitator Family (MFS) transporter K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 528.0
HKD3_k127_6791798_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 493.0
HKD3_k127_6791798_7 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 373.0
HKD3_k127_6791798_8 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000002047 215.0
HKD3_k127_6791798_9 - - - - 0.000000000129 73.0
HKD3_k127_6866701_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.721e-195 616.0
HKD3_k127_6866701_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 567.0
HKD3_k127_6866701_2 DNA polymerase III tau subunit V interacting with alpha K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 522.0
HKD3_k127_6866701_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 327.0
HKD3_k127_6866701_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 294.0
HKD3_k127_6866701_5 Creatinine amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003239 295.0
HKD3_k127_6866701_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000001609 183.0
HKD3_k127_6896670_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 426.0
HKD3_k127_6896670_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000002629 145.0
HKD3_k127_6910216_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 459.0
HKD3_k127_6910216_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 319.0
HKD3_k127_6920116_0 o-acetylhomoserine K01740 - 2.5.1.49 3.596e-217 689.0
HKD3_k127_6920116_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 459.0
HKD3_k127_6920116_2 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004066 267.0
HKD3_k127_6920116_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007144 269.0
HKD3_k127_6920116_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000002755 225.0
HKD3_k127_6920116_5 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000006425 179.0
HKD3_k127_6920116_6 transcriptional K15852 - - 0.00000000000000003149 91.0
HKD3_k127_6920116_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000004984 74.0
HKD3_k127_6961175_0 Subtilase family - - - 5.031e-206 659.0
HKD3_k127_6961175_1 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 405.0
HKD3_k127_6961175_2 Esterase PHB depolymerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 325.0
HKD3_k127_6961175_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000279 242.0
HKD3_k127_6961175_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000006026 186.0
HKD3_k127_6961175_5 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000007884 181.0
HKD3_k127_6961175_6 Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000003841 142.0
HKD3_k127_6965190_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 621.0
HKD3_k127_6965190_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000003733 226.0
HKD3_k127_6965190_2 Methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000225 131.0
HKD3_k127_698048_0 AsmA family K07289,K07290 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002445 272.0
HKD3_k127_698048_1 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000001691 208.0
HKD3_k127_698048_3 araC family - - - 0.000000000005224 79.0
HKD3_k127_7035188_0 Glycosyl hydrolase 36 superfamily, catalytic domain - - - 0.0 1508.0
HKD3_k127_7035188_1 Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity - - - 7.261e-252 804.0
HKD3_k127_7035188_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000005077 162.0
HKD3_k127_7035188_3 oxidoreductase - - - 0.00000000000000002243 83.0
HKD3_k127_7035188_4 - - - - 0.0000005456 59.0
HKD3_k127_7055702_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 565.0
HKD3_k127_7065640_0 Protein of unknown function (DUF1116) K02381 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 445.0
HKD3_k127_7065640_1 CoA-ligase - - - 0.000000000000000000000000000000000000000000000000000000000000001995 229.0
HKD3_k127_7065640_2 - - - - 0.0000002923 62.0
HKD3_k127_71355_0 AFG1-like ATPase K06916 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 440.0
HKD3_k127_71355_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 423.0
HKD3_k127_71355_2 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 345.0
HKD3_k127_7145004_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 1.621e-279 872.0
HKD3_k127_7145004_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184,K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 360.0
HKD3_k127_7145004_2 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000003762 207.0
HKD3_k127_7145004_3 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein - - - 0.00000000000000000000000000000000000005564 149.0
HKD3_k127_725190_0 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000007089 249.0
HKD3_k127_725190_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000001654 106.0
HKD3_k127_725190_2 - - - - 0.000000006051 66.0
HKD3_k127_7252211_0 mandelate racemase muconate lactonizing K01706 - 4.2.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 599.0
HKD3_k127_7252211_1 PFAM fumarylacetoacetate (FAA) hydrolase K18336 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 417.0
HKD3_k127_7252211_2 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 328.0
HKD3_k127_7252211_3 Transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000000000000000003999 205.0
HKD3_k127_7256386_0 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 328.0
HKD3_k127_7256386_1 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.0000000000000002497 79.0
HKD3_k127_7266436_0 carboxylase K01969 - 6.4.1.4 7.415e-268 835.0
HKD3_k127_7266436_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 6.267e-229 744.0
HKD3_k127_7266436_10 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000000003031 207.0
HKD3_k127_7266436_11 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000002147 207.0
HKD3_k127_7266436_12 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000002912 189.0
HKD3_k127_7266436_13 LysE type translocator K11250 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015175,GO:0015179,GO:0015190,GO:0015318,GO:0015658,GO:0015711,GO:0015803,GO:0015804,GO:0015807,GO:0015820,GO:0015849,GO:0016020,GO:0022857,GO:0034220,GO:0042968,GO:0042970,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000001734 192.0
HKD3_k127_7266436_14 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000665 168.0
HKD3_k127_7266436_15 MAPEG family - - - 0.00000000000000000000000000000000001119 140.0
HKD3_k127_7266436_16 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000003347 128.0
HKD3_k127_7266436_17 Protein of unknown function (DUF1289) K06938 - - 0.00000000000001735 85.0
HKD3_k127_7266436_18 Glyoxalase-like domain - - - 0.0000000000004216 79.0
HKD3_k127_7266436_2 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 7.46e-200 639.0
HKD3_k127_7266436_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 596.0
HKD3_k127_7266436_4 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 578.0
HKD3_k127_7266436_5 PFAM Pyruvate carboxyltransferase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 419.0
HKD3_k127_7266436_6 PFAM Glutathione S-transferase domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 308.0
HKD3_k127_7266436_7 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 297.0
HKD3_k127_7266436_8 d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009706 297.0
HKD3_k127_7266436_9 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000009079 208.0
HKD3_k127_7271127_0 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 7.243e-225 709.0
HKD3_k127_7271127_1 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 526.0
HKD3_k127_7271127_10 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 336.0
HKD3_k127_7271127_11 UTRA K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000132 276.0
HKD3_k127_7271127_12 glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.000000000000000000000000000000000000000000000000000000004264 201.0
HKD3_k127_7271127_13 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000001021 143.0
HKD3_k127_7271127_14 - - - - 0.0000000000000000001723 101.0
HKD3_k127_7271127_2 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 457.0
HKD3_k127_7271127_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007998 425.0
HKD3_k127_7271127_4 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 413.0
HKD3_k127_7271127_5 Belongs to the LDH2 MDH2 oxidoreductase family K16844 - 1.1.1.338 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 387.0
HKD3_k127_7271127_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 385.0
HKD3_k127_7271127_7 abc transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 391.0
HKD3_k127_7271127_8 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 361.0
HKD3_k127_7271127_9 Belongs to the peptidase S1C family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 344.0
HKD3_k127_7281679_0 COG1157 Flagellar biosynthesis type III secretory pathway ATPase K02412 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.14 1.534e-226 708.0
HKD3_k127_7281679_1 Flagellar biosynthesis type III secretory pathway protein K02411 - - 0.0000000000000000000000000000000000000000000000000000000000000000003451 238.0
HKD3_k127_7281679_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000002257 102.0
HKD3_k127_7281679_3 flagellar FliJ protein K02413 - - 0.000000000001161 73.0
HKD3_k127_7281679_4 FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02410 - - 0.000000236 52.0
HKD3_k127_7284547_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1132.0
HKD3_k127_7284547_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 553.0
HKD3_k127_7284547_10 Beta/Gamma crystallin - - - 0.0000000000000000000000000000000000000000000000000000000002201 215.0
HKD3_k127_7284547_11 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000000000002305 184.0
HKD3_k127_7284547_12 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000007161 179.0
HKD3_k127_7284547_13 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000009976 171.0
HKD3_k127_7284547_14 Restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000002759 167.0
HKD3_k127_7284547_15 - - - - 0.0000000000000000000000000000000000000000005544 166.0
HKD3_k127_7284547_16 Helix-turn-helix - - - 0.0000000000000000000000000000000000005426 146.0
HKD3_k127_7284547_17 - - - - 0.0000000000000000000000000000001596 136.0
HKD3_k127_7284547_18 oxidation protein (SoxZ) K17227 - - 0.0000000000000000000003414 106.0
HKD3_k127_7284547_19 Luciferase family - - - 0.000000000002452 69.0
HKD3_k127_7284547_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 522.0
HKD3_k127_7284547_20 - - - - 0.00002829 53.0
HKD3_k127_7284547_3 Putative serine dehydratase domain K20757 - 4.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 465.0
HKD3_k127_7284547_4 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 404.0
HKD3_k127_7284547_5 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 358.0
HKD3_k127_7284547_6 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 313.0
HKD3_k127_7284547_7 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000009176 259.0
HKD3_k127_7284547_8 Protein of unknown function (DUF3750) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001278 259.0
HKD3_k127_7284547_9 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000704 209.0
HKD3_k127_7288436_0 RNB K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 583.0
HKD3_k127_7288436_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 374.0
HKD3_k127_7288436_2 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 301.0
HKD3_k127_7288436_3 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000001217 245.0
HKD3_k127_7288436_4 TIGRFAM TonB family protein K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000002908 250.0
HKD3_k127_7288436_5 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000004503 241.0
HKD3_k127_7291797_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 479.0
HKD3_k127_7291797_1 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000008015 153.0
HKD3_k127_7291797_2 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000001318 135.0
HKD3_k127_7291797_3 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.0000000000000004715 78.0
HKD3_k127_7291797_4 NHL repeat - - - 0.000002443 61.0
HKD3_k127_7291797_5 C-terminal domain of CHU protein family - - - 0.000002775 60.0
HKD3_k127_7293008_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.956e-243 757.0
HKD3_k127_7293008_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 3.764e-202 640.0
HKD3_k127_7293008_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000000007914 177.0
HKD3_k127_7293008_11 Protein of unknown function (DUF3299) K09950 - - 0.00000000000000000000000000000000000002596 153.0
HKD3_k127_7293008_12 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000001006 140.0
HKD3_k127_7293008_13 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000000008997 138.0
HKD3_k127_7293008_14 Belongs to the Fur family K03711 - - 0.000000000000000000000000000003155 132.0
HKD3_k127_7293008_15 Alpha/beta hydrolase family - - - 0.0000000000000000000003955 98.0
HKD3_k127_7293008_16 COG0642 Signal transduction histidine kinase - - - 0.000001728 59.0
HKD3_k127_7293008_2 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 489.0
HKD3_k127_7293008_3 benzoate membrane transport protein K05782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 435.0
HKD3_k127_7293008_4 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 370.0
HKD3_k127_7293008_5 Permease, YjgP YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 354.0
HKD3_k127_7293008_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 353.0
HKD3_k127_7293008_7 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002328 290.0
HKD3_k127_7293008_8 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000003785 200.0
HKD3_k127_7293008_9 - - - - 0.0000000000000000000000000000000000000000000000002065 188.0
HKD3_k127_7293852_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 5.08e-239 752.0
HKD3_k127_7293852_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 7.109e-212 686.0
HKD3_k127_7293852_10 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 336.0
HKD3_k127_7293852_11 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 308.0
HKD3_k127_7293852_12 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008362 282.0
HKD3_k127_7293852_13 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 245.0
HKD3_k127_7293852_14 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000005 259.0
HKD3_k127_7293852_15 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000001557 239.0
HKD3_k127_7293852_16 PFAM Cupin 2 conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000006196 221.0
HKD3_k127_7293852_17 Trap-type c4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000002818 218.0
HKD3_k127_7293852_18 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000000000000000000000000000000000000000000000000000000929 197.0
HKD3_k127_7293852_19 Metalloprotease, specifically cleaves on the N-terminal side of aspartyl, glutamyl and cysteic acid residues - - - 0.00000000000000000000000000000000000000000000000003236 205.0
HKD3_k127_7293852_2 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 6.594e-210 660.0
HKD3_k127_7293852_20 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000004528 184.0
HKD3_k127_7293852_21 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000922 186.0
HKD3_k127_7293852_22 protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000000002089 166.0
HKD3_k127_7293852_23 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000002724 124.0
HKD3_k127_7293852_24 protein conserved in bacteria - - - 0.0000000000000000000008392 111.0
HKD3_k127_7293852_25 Thioredoxin - - - 0.000000000000000001581 93.0
HKD3_k127_7293852_3 Psort location Cytoplasmic, score 8.96 K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 626.0
HKD3_k127_7293852_4 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 578.0
HKD3_k127_7293852_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005292 537.0
HKD3_k127_7293852_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 488.0
HKD3_k127_7293852_7 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 487.0
HKD3_k127_7293852_8 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 370.0
HKD3_k127_7293852_9 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 347.0
HKD3_k127_7306173_0 TRAP transporter 4TM 12TM fusion - - - 5.332e-288 921.0
HKD3_k127_7306173_1 oxidase subunit I K00425 - 1.10.3.14 1.334e-212 670.0
HKD3_k127_7306173_10 Domain of unknown function (DUF1850) - - - 0.0000000000000000000001257 107.0
HKD3_k127_7306173_2 oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 492.0
HKD3_k127_7306173_3 Peptidase M48 K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 475.0
HKD3_k127_7306173_4 TRAP transporter solute receptor, TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 456.0
HKD3_k127_7306173_5 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 421.0
HKD3_k127_7306173_6 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001708 271.0
HKD3_k127_7306173_7 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006553 251.0
HKD3_k127_7306173_8 of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000003082 236.0
HKD3_k127_7306173_9 Protein of unknown function (DUF962) - - - 0.00000000000000000000000000000000000001231 163.0
HKD3_k127_7318645_0 AcyL-CoA dehydrogenase K06445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 613.0
HKD3_k127_7318645_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008304 599.0
HKD3_k127_7323301_0 GTPase activity K06207 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006417,GO:0006448,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0034641,GO:0034645,GO:0042802,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045727,GO:0045901,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:2000112 - 1.023e-248 784.0
HKD3_k127_7323301_1 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 577.0
HKD3_k127_7323301_10 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000001413 137.0
HKD3_k127_7323301_11 - - - - 0.0000000000000000000000001887 108.0
HKD3_k127_7323301_2 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 484.0
HKD3_k127_7323301_3 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 445.0
HKD3_k127_7323301_4 membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 415.0
HKD3_k127_7323301_5 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 374.0
HKD3_k127_7323301_6 Probable molybdopterin binding domain K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002235 276.0
HKD3_k127_7323301_7 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001918 258.0
HKD3_k127_7323301_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000009878 243.0
HKD3_k127_7323301_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000009691 150.0
HKD3_k127_7335814_0 MOFRL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 520.0
HKD3_k127_7335814_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000002117 154.0
HKD3_k127_7350369_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 599.0
HKD3_k127_7350369_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 407.0
HKD3_k127_7350369_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 336.0
HKD3_k127_7350369_3 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000000000000000000000000000000323 184.0
HKD3_k127_7354036_0 Domain related to MnhB subunit of Na+/H+ antiporter K00341,K05559 - 1.6.5.3 2.795e-293 927.0
HKD3_k127_7354036_1 (ABC) transporter K11004,K13409 - - 1.58e-223 713.0
HKD3_k127_7354036_10 HlyD membrane-fusion protein of T1SS K02022,K11003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 363.0
HKD3_k127_7354036_11 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 350.0
HKD3_k127_7354036_12 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000004276 209.0
HKD3_k127_7354036_13 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000005576 177.0
HKD3_k127_7354036_14 PFAM regulatory protein, MerR - - - 0.000000000000000000000000000000000000000000000518 169.0
HKD3_k127_7354036_15 Multisubunit Na H antiporter MnhE subunit K05562,K05569 - - 0.0000000000000000000000000000000000000001667 171.0
HKD3_k127_7354036_16 NADH-ubiquinone oxidoreductase subunit 4L K05560 - - 0.00000000000000000000000000000005685 146.0
HKD3_k127_7354036_17 monovalent cation proton antiporter, MnhG PhaG subunit K05564 - - 0.0000000000000000000000002152 110.0
HKD3_k127_7354036_18 Multiple resistance and pH regulation protein F (MrpF / PhaF) K05563 - - 0.000000000000000000004304 105.0
HKD3_k127_7354036_19 Haemolysin-type calcium binding protein related domain K01406 - 3.4.24.40 0.00000000000000004238 96.0
HKD3_k127_7354036_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 4.675e-223 700.0
HKD3_k127_7354036_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 2.118e-218 696.0
HKD3_k127_7354036_4 LUD domain K18929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 606.0
HKD3_k127_7354036_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 574.0
HKD3_k127_7354036_6 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 408.0
HKD3_k127_7354036_7 NADH dehydrogenase (Quinone) K05561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 402.0
HKD3_k127_7354036_8 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 396.0
HKD3_k127_7354036_9 HD domain K13815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 387.0
HKD3_k127_7354671_0 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 454.0
HKD3_k127_7354671_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000004672 214.0
HKD3_k127_7354671_2 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000001484 110.0
HKD3_k127_7367618_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848,K20906 - 5.4.99.2,5.4.99.64 9.204e-279 904.0
HKD3_k127_7367618_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.987e-278 860.0
HKD3_k127_7367618_10 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000001104 145.0
HKD3_k127_7367618_11 FixH family K09926 - - 0.00000000000000000000000000000000002539 144.0
HKD3_k127_7367618_12 - - - - 0.000000000000000000000000000000006794 142.0
HKD3_k127_7367618_13 - - - - 0.00000000000000000000000000001048 121.0
HKD3_k127_7367618_14 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000002647 122.0
HKD3_k127_7367618_15 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000001104 84.0
HKD3_k127_7367618_16 COG4736 Cbb3-type cytochrome oxidase, subunit 3 K00407 - - 0.00000006636 55.0
HKD3_k127_7367618_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.865e-243 758.0
HKD3_k127_7367618_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.807e-241 758.0
HKD3_k127_7367618_4 cytochrome C oxidase - - - 7.244e-196 622.0
HKD3_k127_7367618_5 Cytochrome c oxidase, subunit K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 396.0
HKD3_k127_7367618_6 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 361.0
HKD3_k127_7367618_7 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 333.0
HKD3_k127_7367618_8 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009793 302.0
HKD3_k127_7367618_9 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000003582 202.0
HKD3_k127_7383186_0 Belongs to the methyltransferase superfamily K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 427.0
HKD3_k127_7383186_1 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 417.0
HKD3_k127_7383186_2 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 416.0
HKD3_k127_7383186_3 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 328.0
HKD3_k127_7383186_4 Serine aminopeptidase, S33 K07018 - - 0.00000000000000000000000000000000000000000000000000000000000002618 226.0
HKD3_k127_7383186_5 ferredoxin - - - 0.000000000000000000000000000000000000000000166 162.0
HKD3_k127_7383186_6 VanZ like family - - - 0.00000000000000000000000000000000007924 148.0
HKD3_k127_7383186_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000007433 113.0
HKD3_k127_7383186_8 Protein of unknown function (DUF3460) - - - 0.00000000001065 71.0
HKD3_k127_7388565_0 Protein of unknown function - - - 2.983e-258 844.0
HKD3_k127_7388565_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 2.687e-210 675.0
HKD3_k127_7388565_2 fad dependent oxidoreductase K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 404.0
HKD3_k127_7388565_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 339.0
HKD3_k127_7388565_4 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 317.0
HKD3_k127_7388565_5 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000004692 247.0
HKD3_k127_7388565_6 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000008968 217.0
HKD3_k127_7388565_7 Protein of unknown function (DUF1631) - - - 0.0000000000000000000000000000000000000000000000006188 200.0
HKD3_k127_7388565_8 Protein of unknown function (DUF2788) - - - 0.000000000000000000000000002904 111.0
HKD3_k127_7404875_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 560.0
HKD3_k127_7404875_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 493.0
HKD3_k127_7404875_2 Queuosine biosynthesis protein K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 417.0
HKD3_k127_7404875_3 acetyltransferase K22441 - 2.3.1.57 0.00000000000000000000000000000000000000000000000000000000000006276 217.0
HKD3_k127_7404875_4 PFAM Acyltransferase - - - 0.0000000000000000000000000000000000000000001929 176.0
HKD3_k127_7404875_5 Preprotein translocase subunit YajC K03210 - - 0.00000004773 59.0
HKD3_k127_7406444_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.266e-196 620.0
HKD3_k127_7406444_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 314.0
HKD3_k127_7406444_2 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.0000000000000001237 81.0
HKD3_k127_7413750_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 520.0
HKD3_k127_7413750_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 517.0
HKD3_k127_7413750_2 - - - - 0.0000000000002003 73.0
HKD3_k127_7414852_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 1.26e-238 779.0
HKD3_k127_7414852_1 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 2.448e-238 753.0
HKD3_k127_7414852_10 NYN domain - - - 0.0000000000000000000000000000000006291 132.0
HKD3_k127_7414852_11 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000001133 120.0
HKD3_k127_7414852_12 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.00002196 55.0
HKD3_k127_7414852_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 1.434e-226 711.0
HKD3_k127_7414852_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 595.0
HKD3_k127_7414852_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 498.0
HKD3_k127_7414852_5 ABC transporter transmembrane region K02021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 425.0
HKD3_k127_7414852_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 387.0
HKD3_k127_7414852_7 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 344.0
HKD3_k127_7414852_8 Protein of unknown function, DUF480 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002949 265.0
HKD3_k127_7414852_9 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000006733 167.0
HKD3_k127_7424924_0 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000001097 235.0
HKD3_k127_7424924_1 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000009409 118.0
HKD3_k127_7424924_2 Tetratricopeptide repeat - - - 0.000000000000007473 80.0
HKD3_k127_7424924_3 - - - - 0.00000000000002654 79.0
HKD3_k127_7424924_4 Tetratricopeptide repeat - - - 0.00000000003396 70.0
HKD3_k127_7444648_0 May be involved in recombination K03554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
HKD3_k127_7444648_1 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000112 222.0
HKD3_k127_7444648_2 Hydrolase - - - 0.0000000000003016 71.0
HKD3_k127_7449698_0 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 329.0
HKD3_k127_7449698_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 322.0
HKD3_k127_7469651_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 507.0
HKD3_k127_7474574_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1069.0
HKD3_k127_7474574_1 Participates in both transcription termination and antitermination K02600 - - 6.407e-223 704.0
HKD3_k127_7474574_2 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 448.0
HKD3_k127_7474574_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 301.0
HKD3_k127_7474574_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000002507 163.0
HKD3_k127_7474574_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000005491 141.0
HKD3_k127_7474574_6 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000007337 140.0
HKD3_k127_7513407_0 PFAM Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 504.0
HKD3_k127_7513407_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 435.0
HKD3_k127_7513407_10 methyltransferase activity K00563,K13307,K13330,K15256 - 2.1.1.187,2.1.1.235,2.1.1.324 0.000000000000000000000000000000000000000000000000000000000011 231.0
HKD3_k127_7513407_11 glycosyl transferase family 2 K07011,K20444 - - 0.0000000000000000000000000000000000000000000000000000000001004 228.0
HKD3_k127_7513407_12 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.0000000000000000000000000000000000000000000000000000000007813 232.0
HKD3_k127_7513407_13 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000003609 211.0
HKD3_k127_7513407_14 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000000000000000005006 130.0
HKD3_k127_7513407_15 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000000000001637 115.0
HKD3_k127_7513407_16 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000001457 111.0
HKD3_k127_7513407_17 - - - - 0.000000000000000000002379 98.0
HKD3_k127_7513407_19 galactosyl transferase GMA12/MNN10 family K05531 - - 0.000007264 57.0
HKD3_k127_7513407_2 PFAM transferase hexapeptide repeat containing protein K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 437.0
HKD3_k127_7513407_20 polysaccharide biosynthetic process K20534 - - 0.00001249 57.0
HKD3_k127_7513407_22 Glycosyl transferase 4-like domain - - - 0.0005222 53.0
HKD3_k127_7513407_3 ABC transporter K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 425.0
HKD3_k127_7513407_4 Belongs to the DegT DnrJ EryC1 family K02805,K18653 - 2.6.1.104,2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 363.0
HKD3_k127_7513407_5 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 350.0
HKD3_k127_7513407_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 332.0
HKD3_k127_7513407_7 ABC-2 type transporter K09688,K09690,K09692 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001262 286.0
HKD3_k127_7513407_8 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001125 294.0
HKD3_k127_7513407_9 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003447 257.0
HKD3_k127_7547236_0 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 388.0
HKD3_k127_7547236_1 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002128 247.0
HKD3_k127_7547236_2 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000002656 215.0
HKD3_k127_7547236_3 - - - - 0.000000000000000000000000000000000001352 146.0
HKD3_k127_7549790_0 acetylesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000427 229.0
HKD3_k127_7549790_1 beta-lactamase - - - 0.0000000000000000000000000000000000000000000296 175.0
HKD3_k127_7549790_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000003816 147.0
HKD3_k127_7549790_3 Protein of unknown function (DUF2846) - - - 0.000000000000000000000000000003805 124.0
HKD3_k127_7549790_4 DNA-binding transcription factor activity - - - 0.0000000000000000000000001061 113.0
HKD3_k127_7549790_5 CbiX K03795 - 4.99.1.3 0.0000000000000000916 83.0
HKD3_k127_7549790_6 - - - - 0.00000000007669 70.0
HKD3_k127_7576901_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 4.646e-301 946.0
HKD3_k127_7576901_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008214 626.0
HKD3_k127_7576901_2 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 437.0
HKD3_k127_7576901_3 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 322.0
HKD3_k127_7576901_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000006671 261.0
HKD3_k127_7576901_5 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000002109 239.0
HKD3_k127_7600834_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.564e-204 646.0
HKD3_k127_7600834_1 RND efflux system, outer membrane lipoprotein K18139,K18903 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 423.0
HKD3_k127_7600834_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007589 368.0
HKD3_k127_7600834_3 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000001374 236.0
HKD3_k127_7600834_4 Phasin protein - - - 0.000000000000000000000000001641 120.0
HKD3_k127_7600834_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000002912 89.0
HKD3_k127_7605917_0 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000002224 218.0
HKD3_k127_7605917_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.00000004942 59.0
HKD3_k127_7605917_2 - - - - 0.000001906 59.0
HKD3_k127_7613518_0 Histidine kinase K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 385.0
HKD3_k127_7613518_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 330.0
HKD3_k127_7613518_2 Tetratricopeptide repeat K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000008617 233.0
HKD3_k127_7613518_3 Histidine kinase K07641 - 2.7.13.3 0.000000000001027 81.0
HKD3_k127_7613518_4 von Willebrand factor, type A K07114 - - 0.0005764 50.0
HKD3_k127_7623157_0 FAD linked oxidase domain protein - - - 0.0 1819.0
HKD3_k127_7623157_1 Ammonium Transporter K03320 - - 5.144e-225 710.0
HKD3_k127_7623157_10 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000001808 233.0
HKD3_k127_7623157_11 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000002355 205.0
HKD3_k127_7623157_12 - - - - 0.0000000000000000000000000000000000000000000004334 171.0
HKD3_k127_7623157_13 Alpha beta hydrolase - - - 0.00000000000000000000000000000000002162 153.0
HKD3_k127_7623157_14 Lysin motif - - - 0.000000000000000000000000000000001433 143.0
HKD3_k127_7623157_15 PFAM cytochrome c, class I K08738 - - 0.0000000000000000000000000002761 121.0
HKD3_k127_7623157_16 - - - - 0.0000000000000000000000000006919 130.0
HKD3_k127_7623157_17 Membrane fusogenic activity K09806 - - 0.000000000000000000003039 98.0
HKD3_k127_7623157_18 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000002659 88.0
HKD3_k127_7623157_19 cytochrome K17230 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000003234 83.0
HKD3_k127_7623157_2 Magnesium chelatase, subunit ChlI K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 590.0
HKD3_k127_7623157_20 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.0000000000001165 80.0
HKD3_k127_7623157_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 562.0
HKD3_k127_7623157_4 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 477.0
HKD3_k127_7623157_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 424.0
HKD3_k127_7623157_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 402.0
HKD3_k127_7623157_7 Transcriptional regulatory protein, C terminal K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 300.0
HKD3_k127_7623157_8 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003328 302.0
HKD3_k127_7623157_9 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001016 271.0
HKD3_k127_7626504_0 Transmembrane secretion effector - - - 5.9e-199 634.0
HKD3_k127_7626504_1 Helix-turn-helix domain protein - - - 0.00000000000000000000000000000000000000000000002683 182.0
HKD3_k127_7653405_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 341.0
HKD3_k127_7653405_1 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 338.0
HKD3_k127_7653405_2 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 305.0
HKD3_k127_7653405_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.000000000000000000000000000000000000000000000000000000000000000000004421 241.0
HKD3_k127_7653405_4 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000002549 193.0
HKD3_k127_7653405_5 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000006162 170.0
HKD3_k127_7653405_6 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000005491 143.0
HKD3_k127_7653405_7 Tetratricopeptide repeat - - - 0.00000000000000000000003443 114.0
HKD3_k127_7653405_8 Protein of unknown function (DUF3149) - - - 0.0002151 49.0
HKD3_k127_7653481_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 1.24e-322 1002.0
HKD3_k127_7653481_1 PFAM Glycoside hydrolase 15-related - - - 5.296e-261 824.0
HKD3_k127_7653481_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 538.0
HKD3_k127_7653481_3 PrpF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 389.0
HKD3_k127_7653481_4 Aminoacyl-tRNA editing domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000045 258.0
HKD3_k127_7653481_5 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000000000000000000000000001185 231.0
HKD3_k127_7653481_6 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000007094 189.0
HKD3_k127_7653481_7 transporter component K07112 - - 0.0000000001683 65.0
HKD3_k127_7686952_0 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1332.0
HKD3_k127_7686952_1 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 616.0
HKD3_k127_7686952_10 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000003119 100.0
HKD3_k127_7686952_2 Glucose / Sorbosone dehydrogenase K21430 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016901,GO:0019842,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046872,GO:0048037,GO:0048038,GO:0055114,GO:0070968,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 572.0
HKD3_k127_7686952_3 III protein, CoA-transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 503.0
HKD3_k127_7686952_4 PFAM Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 377.0
HKD3_k127_7686952_5 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000282 261.0
HKD3_k127_7686952_6 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000009648 205.0
HKD3_k127_7686952_7 Extra-cytoplasmic solute receptor family protein 24 - - - 0.0000000000000000000000000000000000000000000000000000006811 199.0
HKD3_k127_7686952_8 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000001082 190.0
HKD3_k127_7686952_9 Bacterial SH3 domain homologues - - - 0.000000000000000000001754 98.0
HKD3_k127_7712489_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.119e-195 625.0
HKD3_k127_7712489_1 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 579.0
HKD3_k127_7712489_10 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000000001839 192.0
HKD3_k127_7712489_11 Alpha beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000001314 181.0
HKD3_k127_7712489_12 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000177 183.0
HKD3_k127_7712489_13 BON domain - - - 0.000000000000000000000000000000000000002543 162.0
HKD3_k127_7712489_14 Belongs to the UPF0102 family K07460 - - 0.000000000000000000000000000003017 124.0
HKD3_k127_7712489_15 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000321 128.0
HKD3_k127_7712489_16 Rubrerythrin - - - 0.000000000000000000000004302 117.0
HKD3_k127_7712489_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 557.0
HKD3_k127_7712489_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07538 - 1.1.1.368 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 511.0
HKD3_k127_7712489_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 430.0
HKD3_k127_7712489_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 390.0
HKD3_k127_7712489_6 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 360.0
HKD3_k127_7712489_7 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 297.0
HKD3_k127_7712489_8 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003855 271.0
HKD3_k127_7712489_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000451 261.0
HKD3_k127_7727267_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.558e-207 665.0
HKD3_k127_7727267_1 Domain of unknown function (DUF5117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007026 476.0
HKD3_k127_7727267_2 - - - - 0.000000000000007218 80.0
HKD3_k127_7729846_0 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000001395 212.0
HKD3_k127_7729846_1 PFAM Peptidase M11 gametolysin - - - 0.00000000000000000000000000000000000000000000000009375 198.0
HKD3_k127_7729846_2 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000000000001673 204.0
HKD3_k127_7729846_3 Metallo-peptidase family M12 - - - 0.00000000000000000000000000000000000000000000008934 189.0
HKD3_k127_7729846_4 Metallo-peptidase family M12 - - - 0.0000000000000000000000000000000000000000000001736 190.0
HKD3_k127_7729846_5 Belongs to the peptidase S8 family - - - 0.0001822 52.0
HKD3_k127_7756915_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 372.0
HKD3_k127_7756915_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000006091 232.0
HKD3_k127_7756915_2 Belongs to the bacterial histone-like protein family - - - 0.00000000000000000000000000000000000001977 147.0
HKD3_k127_7756915_3 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000002421 124.0
HKD3_k127_7759320_0 glutaminyl-tRNA K01886 - 6.1.1.18 3.42e-233 731.0
HKD3_k127_7759320_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 395.0
HKD3_k127_7759320_10 SWI complex, BAF60b domains - - - 0.000000000000000000000000000000000000000388 153.0
HKD3_k127_7759320_11 biopolymer transport K03559 - - 0.000000000000000000000000000000000000001462 153.0
HKD3_k127_7759320_12 Belongs to the UPF0434 family K09791 - - 0.000000000000000003218 87.0
HKD3_k127_7759320_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 320.0
HKD3_k127_7759320_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
HKD3_k127_7759320_4 MotA/TolQ/ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000866 277.0
HKD3_k127_7759320_5 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006536 284.0
HKD3_k127_7759320_6 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002637 269.0
HKD3_k127_7759320_7 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000002278 254.0
HKD3_k127_7759320_8 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000003829 180.0
HKD3_k127_7759320_9 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000385 174.0
HKD3_k127_7764032_0 Phage integrase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000001911 237.0
HKD3_k127_7764032_1 RES - - - 0.0000000000000000000000000000000000000000000000000001693 190.0
HKD3_k127_7764032_2 Protein of unknown function (DUF2384) - - - 0.0000000000000000000000000000002241 137.0
HKD3_k127_7770578_0 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 2.494e-206 661.0
HKD3_k127_7770578_1 PFAM Amidohydrolase 2 K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009495 522.0
HKD3_k127_7770578_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004541 482.0
HKD3_k127_7770578_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 464.0
HKD3_k127_7770578_4 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 319.0
HKD3_k127_7770578_5 LysR substrate binding domain K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003393 304.0
HKD3_k127_7770578_6 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000001728 258.0
HKD3_k127_7770578_7 Protocatechuate 4,5-dioxygenase K04100 - 1.13.11.8 0.000000000000000000000000000000000000000000000004185 191.0
HKD3_k127_7770578_8 - - - - 0.000000000000000000000002138 121.0
HKD3_k127_7786985_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.987e-247 773.0
HKD3_k127_7786985_1 Two component regulator three Y domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007543 422.0
HKD3_k127_7786985_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000004153 119.0
HKD3_k127_7786985_3 Uncharacterized protein family, UPF0114 - - - 0.000000000007023 66.0
HKD3_k127_7814180_0 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004274 269.0
HKD3_k127_7814180_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000006172 201.0
HKD3_k127_7814180_2 - - - - 0.0000000000000105 82.0
HKD3_k127_7814180_3 Belongs to the TPP enzyme family - - - 0.0000000000009693 81.0
HKD3_k127_7835159_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 2.06e-266 833.0
HKD3_k127_7835159_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 512.0
HKD3_k127_7835159_10 Protein of unknown function (DUF1109) - - - 0.000000000000000000000000000000000000000000000000000509 199.0
HKD3_k127_7835159_11 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000001815 196.0
HKD3_k127_7835159_12 Predicted integral membrane protein (DUF2282) - - - 0.000000000000000000000000000000009275 136.0
HKD3_k127_7835159_13 AAA domain K03496 - - 0.0000368 49.0
HKD3_k127_7835159_2 Belongs to the UPF0276 family K09930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 405.0
HKD3_k127_7835159_3 NmrA-like family K19267 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002007 276.0
HKD3_k127_7835159_4 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001193 268.0
HKD3_k127_7835159_5 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000001028 244.0
HKD3_k127_7835159_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000003861 233.0
HKD3_k127_7835159_7 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000002158 232.0
HKD3_k127_7835159_8 Putative DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000006481 240.0
HKD3_k127_7835159_9 Hemerythrin-like metal-binding protein K07216 - - 0.00000000000000000000000000000000000000000000000000000000000009794 220.0
HKD3_k127_7859305_0 Protein of unknown function (DUF2868) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 424.0
HKD3_k127_7859305_1 Domain of unknown function (DUF3482) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007196 288.0
HKD3_k127_7859305_2 transglycosylase - - - 0.00000000000000000000000000000000000000000000003148 175.0
HKD3_k127_78614_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 445.0
HKD3_k127_78614_1 Aminotransferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 344.0
HKD3_k127_78614_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000007315 175.0
HKD3_k127_78614_3 - - - - 0.0000000000000000000000000000000000000000004125 168.0
HKD3_k127_78614_4 - - - - 0.00000000000000000000005292 109.0
HKD3_k127_78614_5 Mycolic acid cyclopropane synthetase - - - 0.000004945 53.0
HKD3_k127_789408_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 4.207e-247 769.0
HKD3_k127_789408_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 505.0
HKD3_k127_789408_10 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000002874 232.0
HKD3_k127_789408_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000003589 222.0
HKD3_k127_789408_12 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000002385 158.0
HKD3_k127_789408_13 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000003741 105.0
HKD3_k127_789408_15 Copper binding periplasmic protein CusF - - - 0.00000000000000000001005 103.0
HKD3_k127_789408_16 Protein of unknown function (DUF3579) - - - 0.00000000000000002326 88.0
HKD3_k127_789408_17 Acetyltransferase (GNAT) domain - - - 0.000000000000001029 85.0
HKD3_k127_789408_18 - - - - 0.0000007887 56.0
HKD3_k127_789408_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 494.0
HKD3_k127_789408_3 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008558 434.0
HKD3_k127_789408_4 ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 434.0
HKD3_k127_789408_5 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 354.0
HKD3_k127_789408_6 transcriptional Regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 340.0
HKD3_k127_789408_7 NnrS protein K07234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002679 278.0
HKD3_k127_789408_8 repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003688 268.0
HKD3_k127_789408_9 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001204 251.0
HKD3_k127_7895406_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 529.0
HKD3_k127_7895406_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 450.0
HKD3_k127_7895406_2 FAD linked oxidase domain protein K00103 - 1.1.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000546 268.0
HKD3_k127_7910817_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000858 466.0
HKD3_k127_7910817_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 310.0
HKD3_k127_7910817_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001306 255.0
HKD3_k127_7910817_3 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000001233 153.0
HKD3_k127_7910817_4 GTPase subunit of restriction endonuclease K07452 - - 0.0000000000000000000888 98.0
HKD3_k127_7910817_5 - - - - 0.000000065 63.0
HKD3_k127_7925011_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 6.321e-263 825.0
HKD3_k127_7925011_1 Rod shape-determining protein MreB K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 336.0
HKD3_k127_7925011_2 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002064 262.0
HKD3_k127_7925011_3 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000001764 163.0
HKD3_k127_7928074_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 1.146e-297 930.0
HKD3_k127_7928074_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 2.371e-292 919.0
HKD3_k127_7928074_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 384.0
HKD3_k127_7928074_3 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 344.0
HKD3_k127_7928074_4 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001539 286.0
HKD3_k127_7928074_6 NAD binding K00015,K00058 - 1.1.1.26,1.1.1.399,1.1.1.95 0.000007789 49.0
HKD3_k127_7962258_0 type II secretion system protein E K02454,K02652,K12276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 556.0
HKD3_k127_7962258_1 General secretion pathway protein K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 333.0
HKD3_k127_7962258_2 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.0000000000000000000000000000000000005015 141.0
HKD3_k127_7962258_3 Protein of unknown function, DUF255 - - - 0.00000000000000000000000000000000002934 153.0
HKD3_k127_8014482_0 SpoVR like protein K06415 - - 8.1e-203 641.0
HKD3_k127_8014482_1 Protein of unknown function (DUF444) K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 420.0
HKD3_k127_8014482_2 PrkA AAA domain K07180 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 299.0
HKD3_k127_8014482_3 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000001018 199.0
HKD3_k127_8014482_4 Barstar (barnase inhibitor) - - - 0.00000000000000003682 86.0
HKD3_k127_8014482_5 Protein of unknown function (DUF541) - - - 0.00000000000000153 89.0
HKD3_k127_802834_0 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 301.0
HKD3_k127_802834_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000234 248.0
HKD3_k127_802834_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000278 63.0
HKD3_k127_803314_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 583.0
HKD3_k127_8050322_0 Glucose / Sorbosone dehydrogenase - - - 1.967e-219 687.0
HKD3_k127_8050322_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001638 272.0
HKD3_k127_8050322_2 Cytochrome c - - - 0.00000000000000000000001103 114.0
HKD3_k127_8050322_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000004263 84.0
HKD3_k127_8088463_0 Fumarate hydratase (Fumerase) K01677,K03779 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 406.0
HKD3_k127_8088463_1 Fumarase C-terminus K01678,K03780 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 312.0
HKD3_k127_8088463_2 Fumarate reductase flavoprotein C-term K00239,K00244 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000033 242.0
HKD3_k127_8094897_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 503.0
HKD3_k127_8094897_1 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000001114 217.0
HKD3_k127_8094897_2 - - - - 0.00000000000000003657 90.0
HKD3_k127_8095809_0 4Fe-4S dicluster domain K18930 - - 0.0 1127.0
HKD3_k127_8095809_1 Aminoacyl-tRNA editing domain K01881 - 6.1.1.15 5.226e-251 790.0
HKD3_k127_8095809_10 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000008231 87.0
HKD3_k127_8095809_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 334.0
HKD3_k127_8095809_3 PFAM 20S proteasome, A and B subunits K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000003077 252.0
HKD3_k127_8095809_4 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002678 232.0
HKD3_k127_8095809_5 Sugar-transfer associated ATP-grasp - - - 0.00000000000000000000000000000000000000000000000000000002354 214.0
HKD3_k127_8095809_6 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000000000000000000000000000000000000000000000008655 206.0
HKD3_k127_8095809_7 transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000000000003535 196.0
HKD3_k127_8095809_8 Universal stress protein - - - 0.0000000000000000000000000000000028 140.0
HKD3_k127_8095809_9 PFAM RNA-binding S4 domain protein K04762 - - 0.000000000000000000000000000000007541 133.0
HKD3_k127_8122629_0 dihydroorotase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 578.0
HKD3_k127_8122629_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000621 169.0
HKD3_k127_8122629_2 Acyltransferase - - - 0.0000000000901 75.0
HKD3_k127_8147765_0 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000581 149.0
HKD3_k127_8147765_1 Branched-chain amino acid transport system / permease component K02057 - - 0.00000000000000000000000000000000009428 135.0
HKD3_k127_8147765_2 - - - - 0.000000000000000000002481 97.0
HKD3_k127_8154981_0 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.942e-251 788.0
HKD3_k127_8154981_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 585.0
HKD3_k127_8154981_10 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000008921 96.0
HKD3_k127_8154981_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 470.0
HKD3_k127_8154981_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 478.0
HKD3_k127_8154981_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 285.0
HKD3_k127_8154981_5 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006862 276.0
HKD3_k127_8154981_6 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000779 228.0
HKD3_k127_8154981_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000001166 188.0
HKD3_k127_8154981_8 Ferredoxin K05337 - - 0.000000000000000000000000000000003359 130.0
HKD3_k127_8154981_9 PFAM CBS domain containing protein - - - 0.0000000000000000000005596 103.0
HKD3_k127_8168431_0 Lanthionine synthetase C-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 457.0
HKD3_k127_8168431_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000001198 109.0
HKD3_k127_8254894_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002726 261.0
HKD3_k127_8254894_1 - - - - 0.000000000000000000000000000000000000000000000000000000001606 208.0
HKD3_k127_8254894_2 GMC oxidoreductase - - - 0.00000000000000000000000000000000004559 136.0
HKD3_k127_8326626_0 Na Pi-cotransporter II-related protein K03324 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 593.0
HKD3_k127_8326626_1 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000007949 248.0
HKD3_k127_8326626_2 Catalyzes the formation of succinate semialdehyde and glutamate from 4-aminobutanoate and 2-oxoglutarate K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000001419 190.0
HKD3_k127_8360673_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 424.0
HKD3_k127_8360673_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004578 289.0
HKD3_k127_8360673_2 PFAM cytochrome c - - - 0.000000000000000000000000000000007729 134.0
HKD3_k127_8360673_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000002259 86.0
HKD3_k127_8360673_4 Transcriptional regulator - - - 0.0002009 46.0
HKD3_k127_8412750_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 380.0
HKD3_k127_8412750_1 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000001513 248.0
HKD3_k127_8412750_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000008042 170.0
HKD3_k127_8412750_3 3-demethylubiquinone-9 3-O-methyltransferase activity K20444 - - 0.000000000000000000000000000002064 138.0
HKD3_k127_8412750_4 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K20444 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000003658 138.0
HKD3_k127_8438894_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 508.0
HKD3_k127_8438894_1 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 387.0
HKD3_k127_8438894_2 Formamidopyrimidine-DNA glycosylase H2TH domain K05522 GO:0000702,GO:0000703,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000131 224.0
HKD3_k127_8442988_0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009957 347.0
HKD3_k127_8442988_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 332.0
HKD3_k127_8442988_2 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000001561 112.0
HKD3_k127_844924_0 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 598.0
HKD3_k127_844924_1 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 563.0
HKD3_k127_844924_2 Aldo keto reductase K00064 - 1.1.1.122 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 421.0
HKD3_k127_844924_3 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 405.0
HKD3_k127_844924_4 Ring hydroxylating alpha subunit (catalytic domain) K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 358.0
HKD3_k127_844924_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003377 336.0
HKD3_k127_844924_6 metal-dependent hydrolase of the TIM-barrel fold K07046 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 352.0
HKD3_k127_844924_7 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001841 280.0
HKD3_k127_844924_8 Collagen triple helix repeat (20 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004289 275.0
HKD3_k127_844924_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000354 109.0
HKD3_k127_8469302_0 Aminotransferase K01845 - 5.4.3.8 1.26e-196 632.0
HKD3_k127_8469302_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 418.0
HKD3_k127_8469302_10 SURF1-like protein - - - 0.00000000000000000000000000000000000000000001212 174.0
HKD3_k127_8469302_11 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0000000000000000000000000000000000007878 139.0
HKD3_k127_8469302_12 signal sequence binding - - - 0.0000000000000000000000000000000005455 146.0
HKD3_k127_8469302_13 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000002292 119.0
HKD3_k127_8469302_14 Protein of unknown function (DUF2909) - - - 0.0000000000002911 72.0
HKD3_k127_8469302_2 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007096 426.0
HKD3_k127_8469302_3 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 402.0
HKD3_k127_8469302_4 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 385.0
HKD3_k127_8469302_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 349.0
HKD3_k127_8469302_6 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002716 257.0
HKD3_k127_8469302_7 oxidase assembly K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000724 224.0
HKD3_k127_8469302_8 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000002801 207.0
HKD3_k127_8469302_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000001701 201.0
HKD3_k127_8488397_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005534 285.0
HKD3_k127_8488397_1 Extracellular ligand-binding receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003272 263.0
HKD3_k127_8488397_2 Redoxin K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000006735 215.0
HKD3_k127_8488397_3 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000002351 169.0
HKD3_k127_8488397_4 Tetratricopeptide repeat protein - - - 0.00000000000000000000000006625 113.0
HKD3_k127_8488397_5 PFAM PhoH family protein K07175 - - 0.00000000000000001371 91.0
HKD3_k127_8489857_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005566 511.0
HKD3_k127_8489857_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 297.0
HKD3_k127_8490279_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000001114 136.0
HKD3_k127_8501385_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.128e-294 921.0
HKD3_k127_8501385_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 1.077e-271 848.0
HKD3_k127_8501385_10 Protein of unknown function (DUF2938) - - - 0.0000000000000000000000000000000000000000000000000000000002041 209.0
HKD3_k127_8501385_11 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000002444 198.0
HKD3_k127_8501385_12 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000002573 177.0
HKD3_k127_8501385_13 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000007824 178.0
HKD3_k127_8501385_14 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.00000000000000000000000000000000000002857 150.0
HKD3_k127_8501385_15 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000008395 112.0
HKD3_k127_8501385_16 relative of glutathione S-transferase, MAPEG superfamily K07136 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000002077 111.0
HKD3_k127_8501385_17 Protein of unknown function (DUF2798) - - - 0.000000000000000000000003662 107.0
HKD3_k127_8501385_18 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000006484 95.0
HKD3_k127_8501385_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 1.09e-219 685.0
HKD3_k127_8501385_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 575.0
HKD3_k127_8501385_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 455.0
HKD3_k127_8501385_5 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 448.0
HKD3_k127_8501385_6 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 346.0
HKD3_k127_8501385_7 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001139 280.0
HKD3_k127_8501385_8 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000006744 239.0
HKD3_k127_8501385_9 Transcriptional regulator K13643 - - 0.00000000000000000000000000000000000000000000000000000000001103 211.0
HKD3_k127_8509132_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.0 1267.0
HKD3_k127_8509132_1 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 4.184e-228 718.0
HKD3_k127_8509132_10 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003007 284.0
HKD3_k127_8509132_11 alpha/beta hydrolase fold K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001462 250.0
HKD3_k127_8509132_12 endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000001517 192.0
HKD3_k127_8509132_13 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000000000000006395 183.0
HKD3_k127_8509132_14 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000004968 176.0
HKD3_k127_8509132_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000001733 161.0
HKD3_k127_8509132_16 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000004319 137.0
HKD3_k127_8509132_17 thioesterase K01075 - 3.1.2.23 0.000000000000000000000000000004916 127.0
HKD3_k127_8509132_18 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000003794 93.0
HKD3_k127_8509132_2 Acyl-CoA dehydrogenase, N-terminal domain K00252 - 1.3.8.6 2.053e-209 657.0
HKD3_k127_8509132_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 495.0
HKD3_k127_8509132_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 500.0
HKD3_k127_8509132_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 426.0
HKD3_k127_8509132_6 PFAM NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 364.0
HKD3_k127_8509132_7 fumarylacetoacetate hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 284.0
HKD3_k127_8509132_8 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019,K07535 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002729 293.0
HKD3_k127_8509132_9 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001113 279.0
HKD3_k127_8523777_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 611.0
HKD3_k127_8523777_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000009499 276.0
HKD3_k127_8523777_2 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000001981 229.0
HKD3_k127_8523777_3 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000003535 188.0
HKD3_k127_8523777_4 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 0.00000000000000000001014 93.0
HKD3_k127_8523777_5 - - - - 0.0000000000000001907 89.0
HKD3_k127_8526766_0 FAD dependent oxidoreductase central domain - - - 1.06e-272 845.0
HKD3_k127_8526766_1 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009518 265.0
HKD3_k127_8526766_2 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000009905 208.0
HKD3_k127_8526766_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000127 165.0
HKD3_k127_8526766_4 triphosphatase activity K18446 - 3.6.1.25 0.000000000000000000000000000000000000000006012 166.0
HKD3_k127_8526766_5 response regulator - - - 0.000001407 53.0
HKD3_k127_8532540_0 Part of the ABC transporter complex FbpABC involved in Fe(3 ) ions import. Responsible for energy coupling to the transport system K02010,K02052 - 3.6.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 492.0
HKD3_k127_8532540_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 306.0
HKD3_k127_8532540_2 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000727 254.0
HKD3_k127_8574626_0 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 472.0
HKD3_k127_8574626_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 356.0
HKD3_k127_8574626_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 301.0
HKD3_k127_8574626_3 Thioredoxin-like - - - 0.0000695 46.0
HKD3_k127_8584183_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 419.0
HKD3_k127_8584183_1 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 359.0
HKD3_k127_8584183_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000994 286.0
HKD3_k127_8584183_3 lipopolysaccharide heptosyltransferase I K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004919 284.0
HKD3_k127_8584183_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001905 257.0
HKD3_k127_8584183_5 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000001094 251.0
HKD3_k127_8584183_6 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000008656 220.0
HKD3_k127_8584183_7 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000003846 121.0
HKD3_k127_8591719_0 Transport of potassium into the cell K03549 - - 2.505e-241 762.0
HKD3_k127_8591719_1 DNA replication, recombination, and repair K07478 - - 8.549e-195 616.0
HKD3_k127_8591719_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 325.0
HKD3_k127_8591719_11 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 307.0
HKD3_k127_8591719_12 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000001269 233.0
HKD3_k127_8591719_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000000000000000000000000000000000000004567 220.0
HKD3_k127_8591719_14 methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000007075 158.0
HKD3_k127_8591719_15 signal peptide protein - - - 0.00000000000000000000000000000000000000339 154.0
HKD3_k127_8591719_16 PEP-CTERM motif - - - 0.000000000000000000000002239 112.0
HKD3_k127_8591719_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 605.0
HKD3_k127_8591719_3 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 619.0
HKD3_k127_8591719_4 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 582.0
HKD3_k127_8591719_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 415.0
HKD3_k127_8591719_6 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 423.0
HKD3_k127_8591719_7 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 383.0
HKD3_k127_8591719_8 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 357.0
HKD3_k127_8591719_9 coenzyme F390 synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 335.0
HKD3_k127_8610362_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.869e-289 903.0
HKD3_k127_8610362_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 5.893e-287 893.0
HKD3_k127_8610362_10 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 297.0
HKD3_k127_8610362_11 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000253 250.0
HKD3_k127_8610362_12 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002167 259.0
HKD3_k127_8610362_13 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000000003371 228.0
HKD3_k127_8610362_14 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000009308 194.0
HKD3_k127_8610362_15 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000004165 194.0
HKD3_k127_8610362_16 Dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000000000002798 174.0
HKD3_k127_8610362_17 oxidation protein K17227 - - 0.0000000000000000000000000000000000000000000006848 167.0
HKD3_k127_8610362_18 FR47-like protein - - - 0.000000000000000000000000000000000000000000003993 188.0
HKD3_k127_8610362_19 acetyltransferase K03825 - - 0.00000000000000000000000000000000000000000127 175.0
HKD3_k127_8610362_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.376e-206 658.0
HKD3_k127_8610362_20 Haem-degrading - - - 0.000000000000000000000000000000000000656 160.0
HKD3_k127_8610362_21 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000001289 147.0
HKD3_k127_8610362_22 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000001374 135.0
HKD3_k127_8610362_23 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000002146 132.0
HKD3_k127_8610362_24 glyoxalase III activity - - - 0.00000000000000000004897 98.0
HKD3_k127_8610362_25 - - - - 0.000000000000003588 85.0
HKD3_k127_8610362_3 Mo-co oxidoreductase dimerisation domain K17225 - - 1.297e-199 633.0
HKD3_k127_8610362_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 1.809e-195 614.0
HKD3_k127_8610362_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005153 591.0
HKD3_k127_8610362_6 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 533.0
HKD3_k127_8610362_7 Thiosulfate-oxidizing multienzyme system protein SoxA K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 367.0
HKD3_k127_8610362_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 338.0
HKD3_k127_8610362_9 cytochrome K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 329.0
HKD3_k127_8617310_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.683e-239 750.0
HKD3_k127_8617310_1 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 581.0
HKD3_k127_8617310_2 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 326.0
HKD3_k127_8624618_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 560.0
HKD3_k127_8624618_1 Protein of unknown function (DUF1326) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 306.0
HKD3_k127_8624618_2 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.00000000000000000000000000000000000000000000000000000000000000002023 239.0
HKD3_k127_8624618_3 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000009272 183.0
HKD3_k127_8624618_4 Modulates RecA activity K03565 - - 0.0000000000000000000000002026 112.0
HKD3_k127_8624618_5 FR47-like protein K22476 - 2.3.1.1 0.000000000007962 67.0
HKD3_k127_8624618_6 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00003126 50.0
HKD3_k127_8656435_0 GntP family permease - - - 5.58e-202 639.0
HKD3_k127_8656435_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 628.0
HKD3_k127_8656435_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005261 251.0
HKD3_k127_8656435_11 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000001499 251.0
HKD3_k127_8656435_12 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001457 236.0
HKD3_k127_8656435_13 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000008392 229.0
HKD3_k127_8656435_14 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000008989 116.0
HKD3_k127_8656435_15 - - - - 0.0006811 46.0
HKD3_k127_8656435_2 AMP-binding enzyme C-terminal domain K18661 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 571.0
HKD3_k127_8656435_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 491.0
HKD3_k127_8656435_4 TonB dependent receptor K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 434.0
HKD3_k127_8656435_5 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 386.0
HKD3_k127_8656435_6 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 342.0
HKD3_k127_8656435_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 319.0
HKD3_k127_8656435_8 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 324.0
HKD3_k127_8656435_9 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 322.0
HKD3_k127_8656490_0 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 493.0
HKD3_k127_8656490_1 Formate/nitrite transporter K21990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 338.0
HKD3_k127_8656490_2 Ser Thr phosphatase family protein K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002194 261.0
HKD3_k127_8656490_3 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.000000000000000000000000000000000000000004253 160.0
HKD3_k127_8657833_0 TRAP-type C4-dicarboxylate transport system, large permease - - - 9.781e-202 637.0
HKD3_k127_8657833_1 Transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 449.0
HKD3_k127_8657833_10 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000001378 136.0
HKD3_k127_8657833_11 UTRA K03710 - - 0.00000000000000000000000009613 116.0
HKD3_k127_8657833_2 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 445.0
HKD3_k127_8657833_3 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 376.0
HKD3_k127_8657833_4 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 330.0
HKD3_k127_8657833_5 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000001738 236.0
HKD3_k127_8657833_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000001134 188.0
HKD3_k127_8657833_7 Protein of unknown function (DUF3667) - - - 0.00000000000000000000000000000000000000000103 171.0
HKD3_k127_8657833_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000009103 162.0
HKD3_k127_8657833_9 thiamine-phosphate kinase activity K00946 - 2.7.4.16 0.0000000000000000000000000000000008031 145.0
HKD3_k127_86628_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.241e-209 678.0
HKD3_k127_86628_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 355.0
HKD3_k127_86628_2 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 301.0
HKD3_k127_86628_3 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001918 277.0
HKD3_k127_8664562_0 amine dehydrogenase activity - - - 4.4e-279 889.0
HKD3_k127_8664562_1 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008785 568.0
HKD3_k127_8664562_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000003386 84.0
HKD3_k127_8664562_11 ensheathment of neurons - - - 0.000007835 51.0
HKD3_k127_8664562_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 546.0
HKD3_k127_8664562_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 321.0
HKD3_k127_8664562_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
HKD3_k127_8664562_5 With different specificities (related to short-chain alcohol - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 294.0
HKD3_k127_8664562_6 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 293.0
HKD3_k127_8664562_7 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000001158 262.0
HKD3_k127_8664562_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005331 250.0
HKD3_k127_8664562_9 Protease prsW family - - - 0.0000000000000000000000000000000000001036 155.0
HKD3_k127_8669578_0 PFAM Hemolysin-type calcium-binding repeat (2 copies) K11005,K11029 GO:0001906,GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005576,GO:0006873,GO:0006874,GO:0006875,GO:0007204,GO:0008150,GO:0009975,GO:0009987,GO:0016829,GO:0016849,GO:0019725,GO:0019835,GO:0030003,GO:0031640,GO:0035821,GO:0042592,GO:0044179,GO:0044364,GO:0044419,GO:0044764,GO:0048878,GO:0050801,GO:0051480,GO:0051704,GO:0051715,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0072503,GO:0072507,GO:0098771 4.6.1.1 0.000000000000000000000000000000000000000004482 162.0
HKD3_k127_8669578_1 Maoc domain protein dehydratase - - - 0.00000000000000000000000000000000004359 141.0
HKD3_k127_8669578_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000002744 102.0
HKD3_k127_8670550_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 518.0
HKD3_k127_8670550_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 510.0
HKD3_k127_8670550_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 435.0
HKD3_k127_8670550_3 GTP-binding GTPase Middle Region K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 428.0
HKD3_k127_8670550_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 341.0
HKD3_k127_8670550_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000004382 201.0
HKD3_k127_8670550_6 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000001942 143.0
HKD3_k127_8670550_7 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000001787 123.0
HKD3_k127_8672635_0 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 2.879e-209 663.0
HKD3_k127_8672635_1 Nicotinate phosphoribosyltransferase (NAPRTase) family K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000001054 218.0
HKD3_k127_8672635_2 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000001303 213.0
HKD3_k127_8672635_3 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000228 173.0
HKD3_k127_8672635_4 PFAM Cold-shock protein, DNA-binding - - - 0.00000000000000000000000000000001873 130.0
HKD3_k127_8672635_5 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000001445 71.0
HKD3_k127_8677282_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 1387.0
HKD3_k127_8677282_1 nitrite transporter K02575 - - 1.434e-318 979.0
HKD3_k127_8677282_2 Major Facilitator Superfamily K02575 - - 1.422e-211 666.0
HKD3_k127_8677282_3 Type IV pili methyl-accepting chemotaxis transducer N-term K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 508.0
HKD3_k127_8677282_4 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 481.0
HKD3_k127_8677282_5 Response regulator receiver domain protein K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000003158 264.0
HKD3_k127_8677282_6 isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000008671 170.0
HKD3_k127_8677282_7 DNA topoisomerase I K03168 - 5.99.1.2 0.0000000000000000006593 92.0
HKD3_k127_8677282_8 BON domain K04065 - - 0.0000000002645 68.0
HKD3_k127_8677561_0 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 296.0
HKD3_k127_8677561_1 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000001367 236.0
HKD3_k127_8677561_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000001615 98.0
HKD3_k127_8677561_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000002993 103.0
HKD3_k127_8677561_4 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000005418 66.0
HKD3_k127_8677561_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000001659 64.0
HKD3_k127_8677561_6 ATP synthase B/B' CF(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000005498 61.0
HKD3_k127_8680369_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 347.0
HKD3_k127_8680369_1 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000001619 181.0
HKD3_k127_8680369_2 Ferredoxin - - - 0.00000000000000000000000000000004251 131.0
HKD3_k127_8684404_0 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 448.0
HKD3_k127_8684404_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 472.0
HKD3_k127_8684404_2 Oxidoreductase family, NAD-binding Rossmann fold K19181 - 1.1.1.292 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 388.0
HKD3_k127_8684404_3 Enoyl-CoA hydratase/isomerase K08299 - 4.2.1.149 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 361.0
HKD3_k127_8684404_4 ABC transporter ATP-binding protein K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 353.0
HKD3_k127_8684404_5 amino acid K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 306.0
HKD3_k127_8684404_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000006153 68.0
HKD3_k127_8684404_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000004003 50.0
HKD3_k127_8686864_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 4.667e-240 770.0
HKD3_k127_8686864_1 PEP-utilising enzyme, TIM barrel domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000002028 227.0
HKD3_k127_8686864_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000002503 176.0
HKD3_k127_8688948_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 472.0
HKD3_k127_8688948_1 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 387.0
HKD3_k127_8688948_2 Belongs to the peptidase M17 family K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 377.0
HKD3_k127_8688948_3 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003556 284.0
HKD3_k127_8688948_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000042 141.0
HKD3_k127_8715671_0 M61 glycyl aminopeptidase - - - 1.974e-219 698.0
HKD3_k127_8715671_1 glycolate oxidase subunit GlcD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 576.0
HKD3_k127_8715671_10 - - - - 0.0000000002747 61.0
HKD3_k127_8715671_11 - - - - 0.000000737 62.0
HKD3_k127_8715671_12 - K06950 - - 0.00000807 59.0
HKD3_k127_8715671_2 Sigma-54 interaction domain protein K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 555.0
HKD3_k127_8715671_3 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 386.0
HKD3_k127_8715671_4 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 349.0
HKD3_k127_8715671_5 phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 312.0
HKD3_k127_8715671_6 Bacterial extracellular solute-binding protein K02020,K22003 - 5.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005466 280.0
HKD3_k127_8715671_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 267.0
HKD3_k127_8715671_8 Protein of unknown function, DUF599 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004014 254.0
HKD3_k127_8715671_9 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000006475 213.0
HKD3_k127_8737916_0 histidine kinase A domain protein - - - 9.246e-259 813.0
HKD3_k127_8737916_1 DNA polymerase III K02342 - 2.7.7.7 4.018e-223 722.0
HKD3_k127_8737916_2 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 594.0
HKD3_k127_8737916_3 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 385.0
HKD3_k127_8737916_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 373.0
HKD3_k127_8737916_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000001494 176.0
HKD3_k127_8748755_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 335.0
HKD3_k127_8748755_1 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.0000000000000000000000000000000000000000000000000000000000001547 221.0
HKD3_k127_8748755_2 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000463 186.0
HKD3_k127_8748755_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000006385 114.0
HKD3_k127_8760994_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 364.0
HKD3_k127_8760994_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 328.0
HKD3_k127_8760994_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 315.0
HKD3_k127_8760994_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000005931 160.0
HKD3_k127_8774069_0 Glutamine synthetase, catalytic domain K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001922 250.0
HKD3_k127_8774069_1 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000000000000000000000000000001382 158.0
HKD3_k127_8774069_2 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000001313 108.0
HKD3_k127_8782435_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 459.0
HKD3_k127_8782435_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000009347 169.0
HKD3_k127_8782619_0 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000000007449 225.0
HKD3_k127_8782619_1 membrane - - - 0.00000000000000000000000000000000000000000001809 176.0
HKD3_k127_8782619_2 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000004326 165.0
HKD3_k127_8782619_3 Type II secretion system (T2SS), protein I K02458 - - 0.00000000000000001538 91.0
HKD3_k127_8782619_4 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.00000000000009835 85.0
HKD3_k127_8782619_5 general secretion pathway protein K02457 - - 0.000000002424 66.0
HKD3_k127_8782619_6 General secretion pathway protein K02459 - - 0.000006666 57.0
HKD3_k127_8782619_7 Type II secretion system (T2SS), protein M - - - 0.00002192 53.0
HKD3_k127_8784999_0 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002621 263.0
HKD3_k127_8784999_1 ThiF family - - - 0.000000000000000000000000000000001622 147.0
HKD3_k127_8784999_2 MerR HTH family regulatory protein K18997 - - 0.00000000000000000007024 91.0
HKD3_k127_8784999_3 proteolysis K03665 - - 0.0000000007583 71.0
HKD3_k127_8784999_4 Ubiquitin-conjugating enzyme E2, catalytic domain homologues - - - 0.00000001255 66.0
HKD3_k127_8784999_5 - - - - 0.0001732 54.0
HKD3_k127_8799572_0 Acyl-CoA synthetase (NDP forming) K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001227 293.0
HKD3_k127_8799572_1 Domain of unknown function (DUF4142) - - - 0.000000000000000000000000000000000949 147.0
HKD3_k127_8804990_0 PFAM Xanthine uracil vitamin C permease K02824 - - 3.891e-202 637.0
HKD3_k127_8804990_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009548 466.0
HKD3_k127_8804990_10 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000000003011 147.0
HKD3_k127_8804990_11 - - - - 0.00000000000000000000000000003229 123.0
HKD3_k127_8804990_12 FabA-like domain - - - 0.00000000000000000000002631 111.0
HKD3_k127_8804990_13 - - - - 0.00000000000000000006621 101.0
HKD3_k127_8804990_14 Phospholipid methyltransferase - - - 0.00000000000007641 80.0
HKD3_k127_8804990_15 - - - - 0.0000000000815 74.0
HKD3_k127_8804990_2 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 476.0
HKD3_k127_8804990_3 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 354.0
HKD3_k127_8804990_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 351.0
HKD3_k127_8804990_5 KR domain K10780 - 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 305.0
HKD3_k127_8804990_6 Phospholipase D Active site motif K01115 - 3.1.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007556 289.0
HKD3_k127_8804990_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000002392 228.0
HKD3_k127_8804990_8 lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000008959 224.0
HKD3_k127_8804990_9 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.00000000000000000000000000000000000000000004743 168.0
HKD3_k127_8829882_0 Belongs to the GPI family K01810 - 5.3.1.9 2.815e-272 846.0
HKD3_k127_8829882_1 Transaldolase/Fructose-6-phosphate aldolase K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 539.0
HKD3_k127_8829882_2 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 310.0
HKD3_k127_8829882_3 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003788 245.0
HKD3_k127_8829882_4 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.000000000000000000000000000000000000005265 152.0
HKD3_k127_8829882_5 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.000000000000006255 80.0
HKD3_k127_8842278_0 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002911 280.0
HKD3_k127_8842278_1 4-Hydroxyphenylpyruvate dioxygenase K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000006757 262.0
HKD3_k127_8842278_2 inositol mono-phosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.000000000000000000000000000000000000000000000000000001784 200.0
HKD3_k127_8842278_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000746 198.0
HKD3_k127_8842278_4 transcriptional K03719 - - 0.00000000000000000000000000000000000000000002865 176.0
HKD3_k127_8842278_5 6-phosphogluconate dehydrogenase - - - 0.0000000000000000000000000000000000371 137.0
HKD3_k127_8847597_0 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 386.0
HKD3_k127_8847597_1 amidohydrolase - - - 0.00000000000000000000000000000000805 128.0
HKD3_k127_8943993_0 Psort location CytoplasmicMembrane, score K17686 - 3.6.3.54 1.055e-247 786.0
HKD3_k127_8943993_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 2.082e-220 705.0
HKD3_k127_8943993_10 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000001136 124.0
HKD3_k127_8943993_11 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000002315 107.0
HKD3_k127_8943993_12 Heavy metal transport detoxification protein K07213 - - 0.000000000000121 85.0
HKD3_k127_8943993_13 - - - - 0.0000004463 52.0
HKD3_k127_8943993_2 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 405.0
HKD3_k127_8943993_3 TIR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 344.0
HKD3_k127_8943993_4 Transcriptional regulator, CadC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 335.0
HKD3_k127_8943993_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 306.0
HKD3_k127_8943993_6 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000109 295.0
HKD3_k127_8943993_7 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005303 265.0
HKD3_k127_8943993_8 NAD(P)H-dependent FMN reductase K19784 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003075 248.0
HKD3_k127_8943993_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000286 143.0
HKD3_k127_8952506_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1067.0
HKD3_k127_8952506_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 606.0
HKD3_k127_8952506_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 515.0
HKD3_k127_8952506_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 411.0
HKD3_k127_8952506_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 406.0
HKD3_k127_8952506_5 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 315.0
HKD3_k127_8952506_6 POTRA domain, FtsQ-type - - - 0.000000000000000000000000000000000000000000002342 174.0
HKD3_k127_8952506_7 - - - - 0.0004005 46.0
HKD3_k127_8952506_8 Protein of unknown function (DUF721) - - - 0.0008163 48.0
HKD3_k127_895731_0 ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1115.0
HKD3_k127_895731_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 432.0
HKD3_k127_895731_2 High-affinity nickel-transport protein K07241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 299.0
HKD3_k127_895731_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004185 258.0
HKD3_k127_895731_4 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000004431 152.0
HKD3_k127_895731_5 Anaerobic ribonucleoside-triphosphate reductase - - - 0.00000000000000007389 84.0
HKD3_k127_895731_6 Uncharacterized conserved protein (DUF2249) - - - 0.0005298 45.0
HKD3_k127_9018965_0 aminopeptidase K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 546.0
HKD3_k127_9018965_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 314.0
HKD3_k127_9018965_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
HKD3_k127_9018965_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000001355 135.0
HKD3_k127_9051848_0 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 389.0
HKD3_k127_9051848_1 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000009767 205.0
HKD3_k127_9051848_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000003507 132.0
HKD3_k127_9051848_3 Putative prokaryotic signal transducing protein - - - 0.00000000000000000004235 94.0
HKD3_k127_9053360_0 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000007636 256.0
HKD3_k127_9053360_1 acid phosphatase activity - - - 0.00000000000000000000001484 110.0
HKD3_k127_9094738_0 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 482.0
HKD3_k127_9094738_1 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007796 258.0
HKD3_k127_9094738_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K22130 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000923 265.0
HKD3_k127_9094738_3 TIGRFAM yecA family protein K07039 - - 0.00000000000000000000000000001624 126.0
HKD3_k127_9094738_4 Uncharacterized conserved protein (DUF2249) - - - 0.000000000002927 68.0
HKD3_k127_9141344_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 486.0
HKD3_k127_9141344_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 453.0
HKD3_k127_9141344_2 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 288.0
HKD3_k127_9141344_3 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001314 291.0
HKD3_k127_91566_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 437.0
HKD3_k127_91566_1 - - - - 0.00000000000000000000002105 114.0
HKD3_k127_91566_2 - - - - 0.0000000004657 72.0
HKD3_k127_9165392_0 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 481.0
HKD3_k127_9165392_1 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000001261 191.0
HKD3_k127_9220286_0 Amidohydrolase family - - - 1.976e-203 646.0
HKD3_k127_922768_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000003582 202.0
HKD3_k127_922768_1 chorismate binding enzyme K02552 - 5.4.4.2 0.0000000000000000000000000000000000000003996 164.0
HKD3_k127_9228923_0 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 506.0
HKD3_k127_9228923_1 ATPase (AAA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 312.0
HKD3_k127_9228923_2 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003383 277.0
HKD3_k127_9228923_3 PFAM Fructosamine - - - 0.00000000000000000000000000000000000000000000000000000000000000003948 233.0
HKD3_k127_9267958_0 TilS substrate binding domain K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 321.0
HKD3_k127_9267958_1 periplasmic K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 301.0
HKD3_k127_9267958_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000008956 143.0
HKD3_k127_9304625_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 5.981e-249 778.0
HKD3_k127_9304625_1 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000007354 145.0
HKD3_k127_9310197_0 abc transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007482 268.0
HKD3_k127_9310197_1 cytochrome - - - 0.0003759 49.0
HKD3_k127_9332626_0 Luciferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 334.0
HKD3_k127_9332626_1 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000138 273.0
HKD3_k127_9358369_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 500.0
HKD3_k127_9358369_1 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 497.0
HKD3_k127_9358369_10 Passenger-associated-transport-repeat - - - 0.0001958 47.0
HKD3_k127_9358369_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 290.0
HKD3_k127_9358369_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 298.0
HKD3_k127_9358369_4 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000141 263.0
HKD3_k127_9358369_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000001655 243.0
HKD3_k127_9358369_6 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000002063 212.0
HKD3_k127_9358369_7 peptidase S1 and S6, chymotrypsin Hap K01337 - 3.4.21.50 0.0000000000000000000000000000000000000000000000000000002975 216.0
HKD3_k127_9358369_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000005836 183.0
HKD3_k127_9358369_9 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000001082 134.0
HKD3_k127_937483_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 426.0
HKD3_k127_937483_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 389.0
HKD3_k127_937483_10 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000001267 162.0
HKD3_k127_937483_11 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000001032 162.0
HKD3_k127_937483_12 ribosomal subunit interface protein K05808 - - 0.00000000000000000000000000000000000409 142.0
HKD3_k127_937483_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 381.0
HKD3_k127_937483_3 P-loop ATPase protein family K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 334.0
HKD3_k127_937483_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 327.0
HKD3_k127_937483_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003899 277.0
HKD3_k127_937483_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000002488 199.0
HKD3_k127_937483_7 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000001121 190.0
HKD3_k127_937483_8 ATP-dependent protease La (LON) substrate-binding domain - - - 0.000000000000000000000000000000000000000000000000001093 190.0
HKD3_k127_937483_9 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000005147 184.0
HKD3_k127_9383023_0 PFAM NHL repeat containing protein - - - 0.0 1166.0
HKD3_k127_9383023_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 464.0
HKD3_k127_9383023_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003316 297.0
HKD3_k127_9383023_3 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000075 281.0
HKD3_k127_9383023_4 regulatory protein GntR HTH - - - 0.000000000000000000000000000000000000000000000000001467 191.0
HKD3_k127_9383023_5 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000003119 188.0
HKD3_k127_9383023_6 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000002239 131.0
HKD3_k127_9383023_7 TfoX N-terminal domain - - - 0.000000000000000000000000000001136 124.0
HKD3_k127_9385800_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 460.0
HKD3_k127_9385800_1 Domain of unknown function DUF21 K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 447.0
HKD3_k127_9385800_2 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.00000000000000000000000000000000000003217 147.0
HKD3_k127_9385800_3 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000984 151.0
HKD3_k127_9419474_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.539e-241 754.0
HKD3_k127_9419474_1 Belongs to the mandelate racemase muconate lactonizing enzyme family K01706 - 4.2.1.40 1.358e-231 745.0
HKD3_k127_9419474_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 451.0
HKD3_k127_9419474_3 helix_turn _helix lactose operon repressor K06145 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 366.0
HKD3_k127_9419474_4 COG0017 Aspartyl asparaginyl-tRNA synthetases K01893 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005568 271.0
HKD3_k127_9419474_5 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000186 153.0
HKD3_k127_9482907_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 367.0
HKD3_k127_9482907_1 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 343.0
HKD3_k127_9482907_2 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000001669 214.0
HKD3_k127_9482907_3 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000002625 152.0
HKD3_k127_9482907_4 - - - - 0.0000000000000000000000004175 116.0
HKD3_k127_9482907_5 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000005627 91.0
HKD3_k127_9540525_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 1.602e-212 683.0
HKD3_k127_9540525_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 526.0
HKD3_k127_9540525_2 arylsulfatase A K01130 - 3.1.6.1 0.00000000000000000000000000004453 119.0
HKD3_k127_9540525_3 response regulator K07689 - - 0.000002198 52.0
HKD3_k127_9596859_0 COG1840 ABC-type Fe3 transport system, periplasmic component K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 554.0
HKD3_k127_9596859_1 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 539.0
HKD3_k127_9596859_2 Peptidase family M20/M25/M40 K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 417.0
HKD3_k127_9596859_3 TOBE domain K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 351.0
HKD3_k127_9596859_4 COG1177 ABC-type spermidine putrescine transport system, permease component II K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001515 304.0
HKD3_k127_9596859_5 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009722 259.0
HKD3_k127_9596859_6 Aldolase/RraA K02553 - - 0.000000000000000000000000000000000000000000000000005563 188.0
HKD3_k127_9596859_7 OsmC-like protein - - - 0.0000000000000000000000000000000000000000001478 160.0
HKD3_k127_9596859_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000006391 151.0
HKD3_k127_9637740_0 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 5.075e-234 731.0
HKD3_k127_9637740_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 531.0
HKD3_k127_9637740_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 457.0