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Overview

ID MAG01862
Name HKD3_bin.50
Sample SMP0048
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class E2
Order DHVEG-1
Family DHVEG-1
Genus SM1-50
Species
Assembly information
Completeness (%) 74.6
Contamination (%) 0.72
GC content (%) 45.0
N50 (bp) 7,727
Genome size (bp) 1,542,886

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1369

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1057058_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 329.0
HKD3_k127_1057058_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002215 275.0
HKD3_k127_1057058_2 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000001258 194.0
HKD3_k127_1057058_3 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000006098 102.0
HKD3_k127_1057058_4 Domain present in carbohydrate binding proteins and sugar hydrolses - - - 0.00000000000000004066 93.0
HKD3_k127_1057058_5 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000009257 81.0
HKD3_k127_119543_0 SMART AAA ATPase K07331 - - 0.000000000000000000000000000000000000001384 156.0
HKD3_k127_119543_1 flagella protein K07327,K07328 - - 0.0000000000000000000004176 106.0
HKD3_k127_119543_2 Archaebacterial flagellin K07330 - - 0.00000000000000002238 87.0
HKD3_k127_119543_3 Archaeal flagellar protein F K07329 - - 0.00000000945 62.0
HKD3_k127_119543_4 PFAM Flagella accessory C family protein K07822 - - 0.000003081 56.0
HKD3_k127_1249415_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 361.0
HKD3_k127_1249415_1 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 358.0
HKD3_k127_1249415_2 DNA polymerase alpha chain like domain - - - 0.0000000000000000000000000000000542 134.0
HKD3_k127_1249415_3 cell wall organization K01448 - 3.5.1.28 0.00000000001186 79.0
HKD3_k127_1249415_4 Belongs to the peptidase S8 family K03561,K12287,K20276 - - 0.0000005594 63.0
HKD3_k127_1249415_5 PFAM class II aldolase adducin family protein - - - 0.0000009989 58.0
HKD3_k127_1249415_6 Lamin Tail Domain - - - 0.000001686 62.0
HKD3_k127_1300147_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K03918 - 2.6.1.19,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 535.0
HKD3_k127_1300147_1 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008928 509.0
HKD3_k127_1300147_2 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 505.0
HKD3_k127_1300147_3 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 450.0
HKD3_k127_1300147_4 resolution of meiotic recombination intermediates - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 343.0
HKD3_k127_1382670_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000002771 136.0
HKD3_k127_1396692_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 3.405e-256 799.0
HKD3_k127_1396692_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 453.0
HKD3_k127_1396692_2 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 436.0
HKD3_k127_1396692_3 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002412 299.0
HKD3_k127_146070_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 553.0
HKD3_k127_146070_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 309.0
HKD3_k127_146070_2 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000000000000000000000004552 147.0
HKD3_k127_1468460_0 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000002845 189.0
HKD3_k127_1468460_1 Belongs to the peptidase S8 family K20276 - - 0.0000000000000000000000005472 123.0
HKD3_k127_1468460_2 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.000000003843 70.0
HKD3_k127_1493017_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 290.0
HKD3_k127_1493017_1 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000000006144 240.0
HKD3_k127_1493017_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000002376 229.0
HKD3_k127_1493017_3 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000001311 199.0
HKD3_k127_1493017_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.00000000000000000000000000000000000001299 151.0
HKD3_k127_1493017_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000003592 52.0
HKD3_k127_1528670_0 agmatine deiminase activity K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 507.0
HKD3_k127_1528670_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 422.0
HKD3_k127_1528670_2 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 385.0
HKD3_k127_1528670_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 364.0
HKD3_k127_1528670_4 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 330.0
HKD3_k127_1528670_5 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.000000000000000000000000000000000000000000000000000000000001896 216.0
HKD3_k127_1528670_6 Domain of unknown function (DUF4314) - - - 0.00000002245 57.0
HKD3_k127_153862_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 602.0
HKD3_k127_153862_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 459.0
HKD3_k127_153862_2 Belongs to the phosphohexose mutase family K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001426 273.0
HKD3_k127_153862_3 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000002848 213.0
HKD3_k127_153862_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000007812 164.0
HKD3_k127_1544480_0 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005457 248.0
HKD3_k127_1544480_1 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000002456 164.0
HKD3_k127_1544480_2 Methyltransferase domain K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000001451 108.0
HKD3_k127_1544480_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000007376 98.0
HKD3_k127_1544480_4 phenylacetate-CoA ligase activity K06046 - 6.2.1.19 0.000000000000254 81.0
HKD3_k127_1544480_5 Hexapeptide repeat of succinyl-transferase - - - 0.000000000001127 77.0
HKD3_k127_1553106_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 515.0
HKD3_k127_1553106_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 311.0
HKD3_k127_1553106_2 Peptidase_C39 like family - - - 0.00000000000000000002669 97.0
HKD3_k127_1577512_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 322.0
HKD3_k127_1577512_1 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000004373 213.0
HKD3_k127_1577512_2 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000000001279 171.0
HKD3_k127_1577512_3 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000002883 117.0
HKD3_k127_1577512_4 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000001855 71.0
HKD3_k127_1577512_5 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00003087 48.0
HKD3_k127_1578602_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008442 341.0
HKD3_k127_1578602_1 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 339.0
HKD3_k127_1578602_10 membrane - - - 0.000000000000000000000004487 115.0
HKD3_k127_1578602_11 PFAM biotin lipoate A B protein ligase - - - 0.0000000002221 66.0
HKD3_k127_1578602_12 PFAM UbiA prenyltransferase - - - 0.0009052 47.0
HKD3_k127_1578602_2 Lipoate-protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009829 311.0
HKD3_k127_1578602_3 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 303.0
HKD3_k127_1578602_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007835 273.0
HKD3_k127_1578602_5 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000002813 213.0
HKD3_k127_1578602_6 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000004556 142.0
HKD3_k127_1578602_7 Papain family cysteine protease - - - 0.0000000000000000000000000000000001706 140.0
HKD3_k127_1578602_8 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000000000000000000001864 121.0
HKD3_k127_1578602_9 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000002434 118.0
HKD3_k127_1582993_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 7.309e-288 898.0
HKD3_k127_1582993_1 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 2.469e-263 840.0
HKD3_k127_1582993_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 357.0
HKD3_k127_1582993_3 PFAM Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000007837 212.0
HKD3_k127_1582993_4 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000005406 206.0
HKD3_k127_1582993_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000884 179.0
HKD3_k127_1582993_6 pfam nmd3 K07562 - - 0.00000000000000000000000000000000000000000000009006 182.0
HKD3_k127_1582993_7 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000002126 63.0
HKD3_k127_1582993_8 Domain of unknown function (DU1801) - - - 0.0000001311 58.0
HKD3_k127_1582993_9 Acyl-protein synthetase, LuxE - - - 0.00001818 50.0
HKD3_k127_1602110_0 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 317.0
HKD3_k127_1602110_1 - - - - 0.00000000000000000000000000000000000007836 148.0
HKD3_k127_1602110_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000009753 116.0
HKD3_k127_1623446_0 Copper-exporting ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 375.0
HKD3_k127_1623446_1 metal-dependent membrane protease K07052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002971 282.0
HKD3_k127_1623446_2 zinc-ribbon domain - - - 0.000000000000000000000000000000000001967 143.0
HKD3_k127_1623446_3 Short C-terminal domain K08982 - - 0.00000000000000000000000000000003387 128.0
HKD3_k127_1623446_4 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000286 130.0
HKD3_k127_1623446_5 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.0001309 53.0
HKD3_k127_1657095_0 peptidyl-lysine modification to peptidyl-hypusine K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 451.0
HKD3_k127_1657095_1 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 321.0
HKD3_k127_1657095_2 COG1691 NCAIR mutase (PurE)-related K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 295.0
HKD3_k127_1657095_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000006716 262.0
HKD3_k127_1657095_4 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000002248 194.0
HKD3_k127_1657095_5 cluster protein-associated redox disulfide domain - - - 0.000000000000004399 76.0
HKD3_k127_1657095_6 - - - - 0.000005854 55.0
HKD3_k127_1670474_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 5.119e-200 634.0
HKD3_k127_1670474_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 417.0
HKD3_k127_1670474_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 390.0
HKD3_k127_1670474_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000000000009243 106.0
HKD3_k127_1670474_4 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.000003126 53.0
HKD3_k127_1674648_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000002226 173.0
HKD3_k127_1674648_1 DREV methyltransferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 - 0.000000000006141 74.0
HKD3_k127_1674648_2 Transglutaminase/protease-like homologues - - - 0.00000002141 66.0
HKD3_k127_168000_0 dipeptide transport K02035 - - 1.333e-194 621.0
HKD3_k127_168000_1 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 477.0
HKD3_k127_168000_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004076 342.0
HKD3_k127_168000_11 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 339.0
HKD3_k127_168000_12 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001262 229.0
HKD3_k127_168000_13 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000009442 227.0
HKD3_k127_168000_14 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000002191 186.0
HKD3_k127_168000_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000001193 180.0
HKD3_k127_168000_16 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005885 168.0
HKD3_k127_168000_17 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000003009 160.0
HKD3_k127_168000_18 PFAM PUA domain containing protein K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000239 140.0
HKD3_k127_168000_19 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000982 104.0
HKD3_k127_168000_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 471.0
HKD3_k127_168000_20 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000007956 90.0
HKD3_k127_168000_21 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000002093 100.0
HKD3_k127_168000_22 Binds to the 23S rRNA K02922 - - 0.000000000001341 68.0
HKD3_k127_168000_23 PKD domain - - - 0.0000003838 63.0
HKD3_k127_168000_24 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0002154 52.0
HKD3_k127_168000_3 asparaginyl-tRNA aminoacylation K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 432.0
HKD3_k127_168000_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 412.0
HKD3_k127_168000_5 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031,K02032,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002381 408.0
HKD3_k127_168000_6 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 403.0
HKD3_k127_168000_7 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 379.0
HKD3_k127_168000_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 372.0
HKD3_k127_168000_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 372.0
HKD3_k127_1686888_0 Pyridoxal-phosphate dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005564 321.0
HKD3_k127_1686888_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000006276 247.0
HKD3_k127_1686888_2 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000003761 213.0
HKD3_k127_1686888_3 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000001345 181.0
HKD3_k127_1686888_4 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000009888 152.0
HKD3_k127_1686888_5 Belongs to the PAPS reductase family. CysH subfamily K00390 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8 0.000000000000000000000000000001387 139.0
HKD3_k127_1686888_6 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.0000000000000000000002684 113.0
HKD3_k127_1686888_7 COG0170 Dolichol kinase - - - 0.000004625 57.0
HKD3_k127_1692650_0 Diacylglycerol kinase catalytic domain K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000119 290.0
HKD3_k127_1692650_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000297 177.0
HKD3_k127_1752919_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000008325 166.0
HKD3_k127_1788374_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 361.0
HKD3_k127_1788374_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000001321 146.0
HKD3_k127_1788374_2 Belongs to the peptidase S8 family K20276 - - 0.000000000000002306 88.0
HKD3_k127_1788374_3 - K03741 - 1.20.4.1 0.000000000001518 72.0
HKD3_k127_1788374_4 Peptidase family C25 - - - 0.000000002262 70.0
HKD3_k127_1788374_5 - - - - 0.0000001857 64.0
HKD3_k127_1806339_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 607.0
HKD3_k127_1806339_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 341.0
HKD3_k127_1806339_2 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000001554 220.0
HKD3_k127_1806339_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000006239 189.0
HKD3_k127_1806339_4 PFAM helix-turn-helix HxlR type - - - 0.0000000000000000000000000000000000000008748 150.0
HKD3_k127_1862844_0 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000007997 173.0
HKD3_k127_1862844_1 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000003413 110.0
HKD3_k127_1862844_2 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000002012 87.0
HKD3_k127_1862844_3 - - - - 0.00000000000001224 80.0
HKD3_k127_1876353_0 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000004625 165.0
HKD3_k127_1876353_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000006517 156.0
HKD3_k127_1876353_2 COG0517 FOG CBS domain - - - 0.0000000000000000000000000000007905 135.0
HKD3_k127_1876353_3 - - - - 0.0000000000002875 71.0
HKD3_k127_1876353_4 PFAM Major Facilitator Superfamily - - - 0.00000000000678 77.0
HKD3_k127_1876353_5 membrane-associated protein domain - - - 0.00000000007215 75.0
HKD3_k127_1876353_6 lycopene cyclase - - - 0.0004528 48.0
HKD3_k127_1888608_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1547.0
HKD3_k127_1888608_1 Belongs to the UPF0434 family - - - 0.00000000000000004771 82.0
HKD3_k127_1909853_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 385.0
HKD3_k127_1909853_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 377.0
HKD3_k127_1909853_2 Asparaginase, N-terminal K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000001896 231.0
HKD3_k127_1909853_3 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000002315 130.0
HKD3_k127_1909853_4 Thrombospondin 3a K04659 GO:0001501,GO:0001503,GO:0003416,GO:0003417,GO:0003674,GO:0005488,GO:0005509,GO:0005539,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005912,GO:0005924,GO:0005927,GO:0007155,GO:0007160,GO:0007275,GO:0007517,GO:0008150,GO:0008201,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009987,GO:0016203,GO:0021700,GO:0022610,GO:0030054,GO:0030055,GO:0030154,GO:0030855,GO:0031012,GO:0031589,GO:0032501,GO:0032502,GO:0032991,GO:0033627,GO:0035265,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043931,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0048471,GO:0048513,GO:0048589,GO:0048646,GO:0048705,GO:0048731,GO:0048799,GO:0048856,GO:0048869,GO:0051216,GO:0060231,GO:0060343,GO:0060346,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0060429,GO:0060538,GO:0061053,GO:0061061,GO:0061383,GO:0061430,GO:0061448,GO:0062023,GO:0070161,GO:0070977,GO:0071695,GO:0097367,GO:0098868,GO:1901681 - 0.00000000000000003083 87.0
HKD3_k127_1909853_5 SpoVT / AbrB like domain - - - 0.0000000001254 65.0
HKD3_k127_1909853_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000001107 66.0
HKD3_k127_1933291_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 485.0
HKD3_k127_1933291_1 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001593 269.0
HKD3_k127_1933291_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000785 159.0
HKD3_k127_1933291_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000001189 77.0
HKD3_k127_1933291_4 - - - - 0.000000007705 61.0
HKD3_k127_196249_0 Male sterility protein - - - 0.000000000000000000000000000000000000000001049 169.0
HKD3_k127_196249_1 Major Facilitator K08369 - - 0.00000000002634 76.0
HKD3_k127_196249_2 Protein of unknown function (DUF424) K09148 - - 0.000002467 50.0
HKD3_k127_196249_3 PFAM Transglutaminase-like - - - 0.0007437 51.0
HKD3_k127_1979086_0 - - - - 0.000000000000000000000000000000000001596 157.0
HKD3_k127_1979086_1 Peptidase family C25 - - - 0.000000000000004091 84.0
HKD3_k127_1979086_2 - - - - 0.0000000001698 73.0
HKD3_k127_1979086_3 - - - - 0.0000001343 59.0
HKD3_k127_2009068_0 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000004921 192.0
HKD3_k127_2009068_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.000000000000000000000005743 110.0
HKD3_k127_2009068_2 Periplasmic binding protein K02016 - - 0.00000000002177 72.0
HKD3_k127_2009068_3 PFAM major facilitator superfamily MFS_1 - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000001229 66.0
HKD3_k127_2015385_0 Transcriptional regulator K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.0000005779 57.0
HKD3_k127_2015385_1 - - - - 0.000008384 54.0
HKD3_k127_2015385_2 - - - - 0.0002622 49.0
HKD3_k127_2104468_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1079.0
HKD3_k127_2104468_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 409.0
HKD3_k127_2104468_2 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000005754 49.0
HKD3_k127_2161350_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 613.0
HKD3_k127_2161350_1 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 361.0
HKD3_k127_2161350_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 331.0
HKD3_k127_2161350_3 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.0000000000000000000000000000000000000000000000000000000001424 214.0
HKD3_k127_2161350_4 - - - - 0.000000000005767 72.0
HKD3_k127_2176102_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 601.0
HKD3_k127_2176102_1 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000001135 167.0
HKD3_k127_2176102_2 KEOPS complex Cgi121-like subunit K09119 - - 0.000000000000000000008488 98.0
HKD3_k127_2176102_3 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000005323 81.0
HKD3_k127_2304778_0 Belongs to the peptidase S16 family - - - 2.022e-285 895.0
HKD3_k127_2304778_1 Spore germination protein K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 296.0
HKD3_k127_2304778_2 G/U mismatch-specific uracil-DNA glycosylase activity K03649 - 3.2.2.28 0.00000000000000000000000000000000000000000000000000000000001117 211.0
HKD3_k127_2304778_3 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000186 205.0
HKD3_k127_2381419_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002254 250.0
HKD3_k127_2381419_1 RibD C-terminal domain K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000008194 214.0
HKD3_k127_2381419_2 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000001332 207.0
HKD3_k127_2381419_3 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000002842 177.0
HKD3_k127_2381419_4 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000002585 126.0
HKD3_k127_2381419_5 - - - - 0.000000000000000009337 94.0
HKD3_k127_2381419_6 Protein of unknown function (DUF3795) - - - 0.00000000000009449 76.0
HKD3_k127_2381419_7 2TM domain - - - 0.00000008048 57.0
HKD3_k127_2389276_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000904 280.0
HKD3_k127_2389276_1 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000006147 106.0
HKD3_k127_2389276_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000001102 75.0
HKD3_k127_2389276_3 AAA-like domain K06915 - - 0.0000000001628 66.0
HKD3_k127_2389276_4 - - - - 0.000006764 51.0
HKD3_k127_2418566_0 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001055 254.0
HKD3_k127_2418566_1 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.000000000000000000000000000001698 134.0
HKD3_k127_2418566_2 Glycoside hydrolase family 44 K01179 - 3.2.1.4 0.0000000000000005229 90.0
HKD3_k127_2418566_3 UbiA prenyltransferase family K20616 - - 0.00000000266 66.0
HKD3_k127_2528213_0 Acyl--CoA ligase K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 484.0
HKD3_k127_2528213_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 395.0
HKD3_k127_2528213_2 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000003548 152.0
HKD3_k127_2530863_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1176.0
HKD3_k127_2530863_1 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 1.397e-201 649.0
HKD3_k127_2530863_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0000000000000000000000000009858 114.0
HKD3_k127_2562098_0 Heat shock 70 kDa protein K04043 - - 7.542e-240 756.0
HKD3_k127_2562098_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 469.0
HKD3_k127_2562098_2 PFAM CBS domain containing protein - - - 0.00000000000000003823 86.0
HKD3_k127_2562098_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000005032 83.0
HKD3_k127_2562098_4 Universal stress protein family - - - 0.000000000000203 76.0
HKD3_k127_2562098_5 PFAM peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000001099 55.0
HKD3_k127_2621706_0 PFAM Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 330.0
HKD3_k127_2621706_1 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000001908 102.0
HKD3_k127_2621706_2 - - - - 0.00000000000007185 84.0
HKD3_k127_2621706_3 PFAM Two component regulator propeller - - - 0.000000001608 70.0
HKD3_k127_2622664_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 309.0
HKD3_k127_2622664_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007321 251.0
HKD3_k127_2622664_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000002531 212.0
HKD3_k127_2622664_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000003996 103.0
HKD3_k127_2622664_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000832 98.0
HKD3_k127_2622664_5 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.000000000000000000008952 98.0
HKD3_k127_2622664_6 NADH ubiquinone oxidoreductase subunit 1 (Chain H) K00337 - 1.6.5.3 0.000000000000000002097 88.0
HKD3_k127_2622664_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000001283 87.0
HKD3_k127_2622664_8 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000002435 72.0
HKD3_k127_2706769_0 PFAM type II secretion system K07333 - - 0.0000000000000000000000001186 123.0
HKD3_k127_2706769_1 PFAM PKD domain containing protein - - - 0.000000000000007032 85.0
HKD3_k127_2706769_2 PKD domain containing protein - - - 0.00001316 53.0
HKD3_k127_2728529_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 317.0
HKD3_k127_2728529_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000004729 214.0
HKD3_k127_2728529_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000003571 177.0
HKD3_k127_2728529_3 lactate metabolic process - - - 0.0000000000008185 80.0
HKD3_k127_2745230_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000001378 226.0
HKD3_k127_2745230_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000000000000000000000000000000000000001163 220.0
HKD3_k127_2745230_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000002812 205.0
HKD3_k127_2745230_3 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000000000001236 139.0
HKD3_k127_2745230_4 SRP19 protein K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005786,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006617,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0022607,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034622,GO:0042886,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0065003,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:0097159,GO:1901363,GO:1990904 - 0.000000002832 63.0
HKD3_k127_2745230_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000001337 61.0
HKD3_k127_2750369_0 ATPase, P-type, K Mg Cd Cu Zn Na Ca Na H-transporter K01531 - 3.6.3.2 3.052e-267 848.0
HKD3_k127_2750369_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000005846 198.0
HKD3_k127_2750369_2 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000002739 171.0
HKD3_k127_2750369_3 VIT family - - - 0.000000000000000000000000000008086 129.0
HKD3_k127_2750369_4 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000001301 121.0
HKD3_k127_2750369_5 - - - - 0.000000000000007839 86.0
HKD3_k127_2757616_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 388.0
HKD3_k127_2757616_1 Thioredoxin domain K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004333 266.0
HKD3_k127_2757616_2 Desulfoferrodoxin K05919 - 1.15.1.2 0.000000000000000000000000000000000000000000000000000006318 192.0
HKD3_k127_2770282_0 coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 463.0
HKD3_k127_2770282_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 348.0
HKD3_k127_2770282_2 Saccharopine dehydrogenase C-terminal domain K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 329.0
HKD3_k127_2770282_3 S-adenosyl-L-methionine-dependent methyltransferase that acts as a component of the wyosine derivatives biosynthesis pathway. Probably methylates N-4 position of wybutosine-86 to produce wybutosine-72 K15450 - 2.1.1.282 0.00000000000000000000000000000000000003478 150.0
HKD3_k127_2793937_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 586.0
HKD3_k127_2793937_1 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 383.0
HKD3_k127_2793937_2 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 329.0
HKD3_k127_2793937_3 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
HKD3_k127_2793937_4 PFAM flavin reductase domain protein FMN-binding - - - 0.000000000000000000000000000000001576 138.0
HKD3_k127_2793937_5 PFAM Transcriptional regulator TrmB - - - 0.000000000000000002989 89.0
HKD3_k127_2793937_6 Protein of unknown function (DUF357) K09728 - - 0.000000000000004717 78.0
HKD3_k127_2850158_0 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009444 336.0
HKD3_k127_2850158_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 313.0
HKD3_k127_2850158_2 Protein of unknown function (DUF401) K09133 - - 0.0000000000000000000000000000000000002744 156.0
HKD3_k127_2911276_0 PFAM carboxyl transferase K01969,K15052 - 2.1.3.15,6.4.1.3,6.4.1.4 2.748e-226 708.0
HKD3_k127_2911276_1 PFAM Carbamoyl-phosphate synthase L chain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 533.0
HKD3_k127_2911276_2 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000002142 250.0
HKD3_k127_2911276_3 Biotin carboxylase C-terminal domain K01968 - 6.4.1.4 0.00000000000001396 81.0
HKD3_k127_3051195_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000003108 235.0
HKD3_k127_3051195_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000002087 240.0
HKD3_k127_3051195_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000001233 225.0
HKD3_k127_3051195_3 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000000000000000000000000000001545 205.0
HKD3_k127_3051195_4 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.0000000000000000000000000000000000000000000000004646 182.0
HKD3_k127_3051195_5 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000001297 161.0
HKD3_k127_3051195_6 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000006681 109.0
HKD3_k127_3051195_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000006139 87.0
HKD3_k127_3051195_8 acid phosphatase activity - - - 0.0000000003351 73.0
HKD3_k127_3067170_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001088 254.0
HKD3_k127_3067170_1 - - - - 0.000000000000000000000000000000000000000000009984 167.0
HKD3_k127_3067170_2 Peptidase family M28 K05994 - 3.4.11.10 0.0000000000000000000000000215 123.0
HKD3_k127_3067170_3 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000008485 107.0
HKD3_k127_3067170_4 - - - - 0.0000000000000000000008007 102.0
HKD3_k127_3067170_5 Cold shock K03704 - - 0.000000000000001496 78.0
HKD3_k127_3067170_6 - - - - 0.000000000008116 70.0
HKD3_k127_3067383_0 Belongs to the serpin family K13963 GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005615,GO:0008150,GO:0009892,GO:0010466,GO:0010605,GO:0010951,GO:0019222,GO:0030162,GO:0030234,GO:0030414,GO:0031323,GO:0031324,GO:0032268,GO:0032269,GO:0043086,GO:0044092,GO:0044421,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0080090,GO:0098772 - 0.000000000000000000000000191 115.0
HKD3_k127_3067383_1 PKD domain - - - 0.00000000000001383 86.0
HKD3_k127_311479_0 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 1.418e-241 762.0
HKD3_k127_311479_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000002584 196.0
HKD3_k127_311479_2 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000002195 166.0
HKD3_k127_311479_3 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000002189 71.0
HKD3_k127_3135363_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 541.0
HKD3_k127_3135363_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000000000000001466 171.0
HKD3_k127_3135363_2 Psort location Periplasmic, score 9.44 K07218 - - 0.000000000000001777 88.0
HKD3_k127_3135363_3 proteins of PilT N-term. Vapc superfamily K07158 - - 0.000000000003173 72.0
HKD3_k127_317342_0 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 436.0
HKD3_k127_317342_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000001 240.0
HKD3_k127_317342_2 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000003084 223.0
HKD3_k127_317342_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000002067 199.0
HKD3_k127_317342_4 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000000000000000000000001506 169.0
HKD3_k127_317342_5 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000001699 81.0
HKD3_k127_317342_6 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000001911 74.0
HKD3_k127_317342_7 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0003627 47.0
HKD3_k127_3226981_0 helicase superfamily c-terminal domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 544.0
HKD3_k127_3249944_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 400.0
HKD3_k127_3249944_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000003919 140.0
HKD3_k127_3249944_2 amine dehydrogenase activity - - - 0.00009193 55.0
HKD3_k127_3249944_3 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.0009721 46.0
HKD3_k127_3270956_0 PFAM Nitroreductase - - - 0.0000000000000000003834 101.0
HKD3_k127_336562_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.79e-255 807.0
HKD3_k127_336562_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 301.0
HKD3_k127_336562_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000001019 208.0
HKD3_k127_336562_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000002184 102.0
HKD3_k127_336562_4 Ribosome maturation protein K14574 - - 0.0000000000824 64.0
HKD3_k127_3461461_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 403.0
HKD3_k127_3461461_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036,K02068,K06857 - 3.6.3.27,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 320.0
HKD3_k127_3461461_10 COG2002 Regulators of stationary sporulation gene expression - - - 0.0000000002542 62.0
HKD3_k127_3461461_11 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.00002443 47.0
HKD3_k127_3461461_2 ABC-type phosphate transport system, periplasmic component K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005257 277.0
HKD3_k127_3461461_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002001 274.0
HKD3_k127_3461461_4 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 261.0
HKD3_k127_3461461_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000148 257.0
HKD3_k127_3461461_6 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000005146 247.0
HKD3_k127_3461461_7 BioY protein K03523 - - 0.0000000000000000000000000000000000000000000000000000000000000005213 226.0
HKD3_k127_3461461_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000005125 144.0
HKD3_k127_3461461_9 Ribosomal protein L23 K02892 - - 0.000000000000000004422 88.0
HKD3_k127_347449_0 helicase activity - - - 1.926e-297 932.0
HKD3_k127_347449_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003215 285.0
HKD3_k127_347449_2 PFAM Fibronectin type III domain - - - 0.000000000000000000000000000000000000007045 159.0
HKD3_k127_3492942_0 homogentisate phytyltransferase activity K09833 GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006766,GO:0006775,GO:0006810,GO:0008150,GO:0008152,GO:0008610,GO:0008643,GO:0009058,GO:0009110,GO:0009266,GO:0009507,GO:0009536,GO:0009628,GO:0009915,GO:0009987,GO:0010176,GO:0010189,GO:0010232,GO:0010233,GO:0010354,GO:0015766,GO:0015770,GO:0015772,GO:0016043,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019752,GO:0031347,GO:0032501,GO:0032787,GO:0033559,GO:0042360,GO:0042362,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046394,GO:0046483,GO:0048583,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071554,GO:0071555,GO:0071702,GO:0071704,GO:0071840,GO:0072330,GO:0080134,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 2.5.1.115,2.5.1.116 0.00000001285 66.0
HKD3_k127_3492942_1 Flavin containing amine oxidoreductase - - - 0.00000003424 64.0
HKD3_k127_352209_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 1.332e-230 720.0
HKD3_k127_352209_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 377.0
HKD3_k127_3541452_0 Phenylalanyl-tRNA synthetase beta K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 481.0
HKD3_k127_3541452_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000969 353.0
HKD3_k127_3541452_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000008823 235.0
HKD3_k127_3541452_3 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000001456 227.0
HKD3_k127_3541452_4 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000005942 122.0
HKD3_k127_3544958_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000004087 203.0
HKD3_k127_3544958_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000008252 165.0
HKD3_k127_3544958_2 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.0000000000000000000001391 101.0
HKD3_k127_3544958_3 - - - - 0.0000000000000000000004403 100.0
HKD3_k127_3544958_4 Belongs to the peptidase M50B family - - - 0.0000001054 55.0
HKD3_k127_3544958_5 FG-GAP repeat - - - 0.0000001332 55.0
HKD3_k127_3544958_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000004166 59.0
HKD3_k127_3571737_0 Co Zn Cd efflux system component K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000001556 235.0
HKD3_k127_3571737_1 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000001687 121.0
HKD3_k127_3571737_2 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000001296 111.0
HKD3_k127_3571737_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 0.00000000000000009258 81.0
HKD3_k127_3592464_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 533.0
HKD3_k127_3592464_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 357.0
HKD3_k127_3592464_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000005113 226.0
HKD3_k127_3592464_3 TIGRFAM segregation and condensation protein B K06024 - - 0.00000000000000000000000000000002863 133.0
HKD3_k127_3592464_4 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000007364 112.0
HKD3_k127_3592464_5 deoxyhypusine monooxygenase activity - - - 0.0000001562 57.0
HKD3_k127_3592464_6 Glycosyl hydrolases family 18 K01183 - 3.2.1.14 0.0000005516 63.0
HKD3_k127_3637258_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 452.0
HKD3_k127_3637258_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 299.0
HKD3_k127_3637258_10 - - - - 0.000000000000000000001584 102.0
HKD3_k127_3637258_11 Helix-turn-helix K07108 - - 0.00000000000001258 79.0
HKD3_k127_3637258_12 protein contain chitin-binding domain type 3 K21606 - 3.2.1.202 0.00002653 57.0
HKD3_k127_3637258_13 Bacterial Ig-like domain (group 3) - - - 0.00005627 51.0
HKD3_k127_3637258_14 oxidoreductase activity - - - 0.0001781 50.0
HKD3_k127_3637258_2 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 293.0
HKD3_k127_3637258_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002732 271.0
HKD3_k127_3637258_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005939 261.0
HKD3_k127_3637258_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001739 258.0
HKD3_k127_3637258_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000006101 196.0
HKD3_k127_3637258_7 PFAM SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000004304 175.0
HKD3_k127_3637258_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000003172 162.0
HKD3_k127_3637258_9 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000522 112.0
HKD3_k127_3662171_0 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 345.0
HKD3_k127_3662171_1 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000003147 241.0
HKD3_k127_3662171_2 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000002636 239.0
HKD3_k127_3662171_3 PQQ enzyme repeat - - - 0.000000000000000000000000000007881 126.0
HKD3_k127_3662171_4 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000007213 83.0
HKD3_k127_3754433_0 Male sterility protein - - - 0.000000000000000000000000000000000000000000008887 174.0
HKD3_k127_3754433_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179,K17105 - 2.5.1.39,2.5.1.42 0.0000000000000000000000000000000000000000006677 169.0
HKD3_k127_375526_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 364.0
HKD3_k127_375526_1 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 310.0
HKD3_k127_375526_2 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 292.0
HKD3_k127_375526_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000059 203.0
HKD3_k127_375526_4 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000000000003624 190.0
HKD3_k127_375526_5 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.000000000000000000000000000000007512 131.0
HKD3_k127_375526_6 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000007674 123.0
HKD3_k127_375526_7 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000002025 60.0
HKD3_k127_3799014_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 3.887e-313 973.0
HKD3_k127_3799014_1 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 380.0
HKD3_k127_3799014_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004967 294.0
HKD3_k127_3799014_3 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 268.0
HKD3_k127_3799014_4 Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
HKD3_k127_3799014_5 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.0000000000000000000000000000000000000000000000001545 185.0
HKD3_k127_3799014_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000002958 98.0
HKD3_k127_3799014_7 sequence-specific DNA binding K07108 - - 0.000000000000007257 78.0
HKD3_k127_3799014_8 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000001726 75.0
HKD3_k127_3812795_0 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 421.0
HKD3_k127_3812795_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 312.0
HKD3_k127_3812795_2 - - - - 0.000002557 51.0
HKD3_k127_3812795_3 Periplasmic Protein - - - 0.0007574 51.0
HKD3_k127_3816113_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 409.0
HKD3_k127_3816113_1 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 346.0
HKD3_k127_3816113_10 PFAM Peptidase C1A, papain - - - 0.00000000000001484 86.0
HKD3_k127_3816113_11 PFAM NHL repeat containing protein - - - 0.00000004303 65.0
HKD3_k127_3816113_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 329.0
HKD3_k127_3816113_3 Peptidase S9 prolyl oligopeptidase active site K01281 - 3.4.14.11 0.0000000000000000000000000000000000000000000000000000000000000000000002708 249.0
HKD3_k127_3816113_4 Fic/DOC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001724 244.0
HKD3_k127_3816113_5 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.0000000000000000000000000000000000000000000000000004695 204.0
HKD3_k127_3816113_6 - - - - 0.000000000000000000000000000000000000000000004417 165.0
HKD3_k127_3816113_7 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000001804 155.0
HKD3_k127_3816113_8 Protein of unknown function (DUF3795) - - - 0.000000000000000000000001728 106.0
HKD3_k127_3816113_9 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000001364 109.0
HKD3_k127_3852501_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 422.0
HKD3_k127_3852501_1 Acyl-CoA reductase (LuxC) - - - 0.000000000000000000000000000000000000000000000000000000008608 217.0
HKD3_k127_3852501_2 SCP-2 sterol transfer family - - - 0.00000000000000000000000000000000009123 136.0
HKD3_k127_3852501_3 YHS domain - - - 0.000000000000000000003546 93.0
HKD3_k127_3903962_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 330.0
HKD3_k127_3903962_1 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000001033 237.0
HKD3_k127_3903962_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000003548 152.0
HKD3_k127_3903962_3 PAP2 superfamily - - - 0.000000000000000000003649 103.0
HKD3_k127_3903962_4 GTPase of unknown function C-terminal K06942 - - 0.00000000000000001983 82.0
HKD3_k127_3917492_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 501.0
HKD3_k127_3917492_1 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 370.0
HKD3_k127_3917492_10 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000000000002561 116.0
HKD3_k127_3917492_11 SMART Cystathionine beta-synthase, core - - - 0.00000000000000000000001528 107.0
HKD3_k127_3917492_12 cheY-homologous receiver domain K07668 - - 0.000000000000000000001118 98.0
HKD3_k127_3917492_13 Thiamine-binding protein - - - 0.00000000000000002087 85.0
HKD3_k127_3917492_14 AMP binding - - - 0.000000000000008559 79.0
HKD3_k127_3917492_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000003828 78.0
HKD3_k127_3917492_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 331.0
HKD3_k127_3917492_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 310.0
HKD3_k127_3917492_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.000000000000000000000000000000000000000000000000000000001114 227.0
HKD3_k127_3917492_5 Integral membrane sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000002569 215.0
HKD3_k127_3917492_6 Archaeal holliday junction resolvase (hjc) - - - 0.00000000000000000000000000000000000000000000029 174.0
HKD3_k127_3917492_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000002647 169.0
HKD3_k127_3917492_8 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.00000000000000000000000000000000004578 145.0
HKD3_k127_3917492_9 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000003134 136.0
HKD3_k127_3945389_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 514.0
HKD3_k127_3945389_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 306.0
HKD3_k127_3945389_10 PFAM NHL repeat containing protein - - - 0.00000006504 66.0
HKD3_k127_3945389_11 FIST N domain - - - 0.0007623 51.0
HKD3_k127_3945389_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000006025 194.0
HKD3_k127_3945389_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000116 186.0
HKD3_k127_3945389_4 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.000000000000000000000000000000000000000000000003045 188.0
HKD3_k127_3945389_5 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000000000000000000000003899 155.0
HKD3_k127_3945389_6 SMART Prolyl 4-hydroxylase, alpha subunit - - - 0.00000000000000000000000000000000000002552 159.0
HKD3_k127_3945389_7 oxidoreductase activity - - - 0.0000000000000000000000000002256 126.0
HKD3_k127_3945389_8 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000003864 120.0
HKD3_k127_3945389_9 Parallel beta-helix - - - 0.00000000003766 74.0
HKD3_k127_3974948_0 PFAM type II secretion system protein E K07332 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 530.0
HKD3_k127_3974948_1 PFAM type II secretion system protein E K07332 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 511.0
HKD3_k127_3974948_2 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000001408 175.0
HKD3_k127_4021368_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1122.0
HKD3_k127_4021368_1 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 459.0
HKD3_k127_4021368_2 carbohydrate derivative binding K13525,K14575 GO:0001655,GO:0001657,GO:0001658,GO:0001763,GO:0001822,GO:0001823,GO:0001932,GO:0001933,GO:0002009,GO:0003674,GO:0003824,GO:0004857,GO:0004860,GO:0005102,GO:0005178,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006469,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0008150,GO:0009653,GO:0009887,GO:0009888,GO:0009892,GO:0010563,GO:0010594,GO:0010595,GO:0010605,GO:0010632,GO:0010634,GO:0010941,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019207,GO:0019210,GO:0019220,GO:0019222,GO:0019887,GO:0019899,GO:0019900,GO:0019901,GO:0022603,GO:0030234,GO:0030334,GO:0030335,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0033673,GO:0035239,GO:0035295,GO:0040012,GO:0040017,GO:0042325,GO:0042326,GO:0043086,GO:0043535,GO:0043536,GO:0043549,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0045765,GO:0045766,GO:0045859,GO:0045936,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048729,GO:0048731,GO:0048754,GO:0048856,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050839,GO:0051094,GO:0051171,GO:0051172,GO:0051174,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051270,GO:0051272,GO:0051338,GO:0051348,GO:0060255,GO:0060322,GO:0060429,GO:0060548,GO:0060562,GO:0060675,GO:0060993,GO:0061138,GO:0061326,GO:0061333,GO:0065007,GO:0065009,GO:0072001,GO:0072006,GO:0072009,GO:0072028,GO:0072073,GO:0072078,GO:0072080,GO:0072088,GO:0072163,GO:0072164,GO:0072171,GO:0080090,GO:0090049,GO:0090050,GO:0098772,GO:1901342,GO:1903670,GO:1903672,GO:1904018,GO:2000026,GO:2000145,GO:2000147 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 418.0
HKD3_k127_4021368_3 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000000000002565 240.0
HKD3_k127_4021368_4 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000002838 214.0
HKD3_k127_4021368_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.000000000000000000000000000000000001315 141.0
HKD3_k127_4021368_6 PRC-barrel domain - - - 0.0000000000000007711 79.0
HKD3_k127_4021368_8 - - - - 0.000009184 55.0
HKD3_k127_4028236_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 297.0
HKD3_k127_4028236_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001161 261.0
HKD3_k127_4028236_10 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000003428 168.0
HKD3_k127_4028236_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000006497 168.0
HKD3_k127_4028236_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000005314 148.0
HKD3_k127_4028236_13 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001048 145.0
HKD3_k127_4028236_14 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000004054 145.0
HKD3_k127_4028236_15 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000009254 134.0
HKD3_k127_4028236_16 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000424 108.0
HKD3_k127_4028236_17 ribosomal protein S14 K02954 - - 0.000000000000000009392 83.0
HKD3_k127_4028236_18 Ribosomal L29 protein K02904 - - 0.00000000000000002864 83.0
HKD3_k127_4028236_19 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000001869 81.0
HKD3_k127_4028236_2 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005023 256.0
HKD3_k127_4028236_20 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005732,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000001149 57.0
HKD3_k127_4028236_3 TIGRFAM TraB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000005045 239.0
HKD3_k127_4028236_4 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000004582 229.0
HKD3_k127_4028236_5 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000008536 194.0
HKD3_k127_4028236_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000003606 181.0
HKD3_k127_4028236_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000001137 183.0
HKD3_k127_4028236_8 Ribosomal protein L30p/L7e K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001328 178.0
HKD3_k127_4028236_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000002192 170.0
HKD3_k127_4051153_0 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000173 199.0
HKD3_k127_4051153_1 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000596 166.0
HKD3_k127_4051153_2 - - - - 0.0000000000000000000000000000000001682 136.0
HKD3_k127_4051153_3 - - - - 0.0000000000000000000000001977 108.0
HKD3_k127_4051153_4 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000003887 65.0
HKD3_k127_4403507_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.785e-214 685.0
HKD3_k127_4403507_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 375.0
HKD3_k127_4403507_2 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase - - - 0.0000000000000000000000006069 119.0
HKD3_k127_4403507_3 Aminotransferase - - - 0.000000000000000000134 102.0
HKD3_k127_4403507_4 Short-chain dehydrogenase reductase sdr - - - 0.00004389 46.0
HKD3_k127_4414574_0 PFAM Type II secretion system F domain K07333 - - 0.00000000000000000000000000000000000000000000000000000000000001279 231.0
HKD3_k127_4414574_1 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 - - 0.0000000000000000000000000000000000004161 148.0
HKD3_k127_4414574_2 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000000000003484 143.0
HKD3_k127_4414574_3 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000000002196 134.0
HKD3_k127_4414574_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000000003748 132.0
HKD3_k127_4538762_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 533.0
HKD3_k127_4538762_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 466.0
HKD3_k127_4538762_10 Pectate lyase - - - 0.00000000431 70.0
HKD3_k127_4538762_11 thymidylate synthase K00560 - 2.1.1.45 0.00000007956 58.0
HKD3_k127_4538762_2 COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004557 334.0
HKD3_k127_4538762_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step. MtrH catalyzes the transfer of the methyl group from methyl-tetrahydromethanopterin to the corrinoid prosthetic group of MtrA K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000009571 177.0
HKD3_k127_4538762_4 PFAM Methionine synthase, vitamin-B12 independent K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000000000000000000000000000000000004872 176.0
HKD3_k127_4538762_5 - - - - 0.00000000000000000000000000000002015 136.0
HKD3_k127_4538762_6 Peptidase M50 - - - 0.00000000000000000000000000000337 129.0
HKD3_k127_4538762_7 OB-fold nucleic acid binding domain - - - 0.00000000000000000000002574 110.0
HKD3_k127_4538762_8 TraB family - - - 0.00000000000000000006486 91.0
HKD3_k127_4538762_9 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000001106 62.0
HKD3_k127_4584215_0 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007325 300.0
HKD3_k127_4584215_1 COG0346 Lactoylglutathione lyase and related lyases K07032 - - 0.00000000000000000000000000000000000000000000000002905 181.0
HKD3_k127_4584215_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000003521 77.0
HKD3_k127_4584215_3 Endopeptidase La K04076 - 3.4.21.53 0.00004849 48.0
HKD3_k127_4584215_4 COG NOG29868 non supervised orthologous group - - - 0.0006157 51.0
HKD3_k127_4604823_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002252 276.0
HKD3_k127_4604823_1 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000003982 163.0
HKD3_k127_4604823_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000007141 94.0
HKD3_k127_4604823_3 Tyrosine recombinase XerC K04763 - - 0.0002644 53.0
HKD3_k127_4699135_0 DNA primase K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 416.0
HKD3_k127_4699135_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 298.0
HKD3_k127_4699135_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000002617 104.0
HKD3_k127_4699135_3 - - - - 0.000000000000001929 82.0
HKD3_k127_4699135_4 Uncharacterised protein family UPF0058 - - - 0.0000001262 57.0
HKD3_k127_4730506_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 445.0
HKD3_k127_4730506_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000001174 246.0
HKD3_k127_4730506_2 - - - - 0.000008774 50.0
HKD3_k127_4730506_3 ABC-type uncharacterized transport system - - - 0.0004685 53.0
HKD3_k127_4852990_0 Sulfotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008444 265.0
HKD3_k127_4852990_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000001493 232.0
HKD3_k127_4852990_2 PFAM Peptidase M19, renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000001966 238.0
HKD3_k127_4852990_3 Flavodoxin - GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000001597 199.0
HKD3_k127_4852990_4 glucosylceramidase activity - - - 0.0000000000000000000000000007772 117.0
HKD3_k127_4852990_5 PFAM glycosyl hydrolase 53 domain protein K01224 - 3.2.1.89 0.00000000000000000000000001124 123.0
HKD3_k127_4852990_6 - - - - 0.000000000000000000000000105 109.0
HKD3_k127_4852990_7 TfoX N-terminal domain - - - 0.000000000008799 69.0
HKD3_k127_4852990_8 - - - - 0.000000004415 66.0
HKD3_k127_4852990_9 Acetyltransferase (GNAT) domain - - - 0.00000006879 60.0
HKD3_k127_4864311_0 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 323.0
HKD3_k127_4864311_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000002361 193.0
HKD3_k127_4864311_2 PRC-barrel domain - - - 0.00000000000005626 76.0
HKD3_k127_4901849_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 359.0
HKD3_k127_4901849_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.00000000000000000000000000006028 117.0
HKD3_k127_4901849_2 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000008244 121.0
HKD3_k127_4901849_3 - - - - 0.000000000000008397 83.0
HKD3_k127_4901849_4 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.0000000000001318 71.0
HKD3_k127_4901849_5 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000008397 64.0
HKD3_k127_490395_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 433.0
HKD3_k127_490395_1 Aconitase family (aconitate hydratase) K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000001808 265.0
HKD3_k127_490395_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000002338 192.0
HKD3_k127_490395_3 Chlorophyllase - - - 0.00000000003577 64.0
HKD3_k127_4919221_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 405.0
HKD3_k127_4919221_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 349.0
HKD3_k127_4919221_10 AraC-like ligand binding domain - - - 0.00000000000000000000000001487 119.0
HKD3_k127_4919221_11 dienelactone hydrolase - - - 0.00000000000000000000003237 107.0
HKD3_k127_4919221_12 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000000002858 78.0
HKD3_k127_4919221_13 dienelactone hydrolase - - - 0.0000000000003146 80.0
HKD3_k127_4919221_14 Rubrerythrin - - - 0.00004721 48.0
HKD3_k127_4919221_15 amine dehydrogenase activity - - - 0.0001486 49.0
HKD3_k127_4919221_16 Archaeal Type IV pilin, N-terminal K01698 - 4.2.1.24 0.0003129 47.0
HKD3_k127_4919221_2 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 300.0
HKD3_k127_4919221_3 ZIP Zinc transporter K07238,K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000837 250.0
HKD3_k127_4919221_4 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000000000000000000000000000000000000835 219.0
HKD3_k127_4919221_5 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000006925 212.0
HKD3_k127_4919221_6 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000001325 204.0
HKD3_k127_4919221_7 Ferritin-like domain K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000001958 192.0
HKD3_k127_4919221_8 NUDIX domain - - - 0.000000000000000000000000000000000008266 140.0
HKD3_k127_4919221_9 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000005136 121.0
HKD3_k127_4966355_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000004174 214.0
HKD3_k127_4966355_1 dUTPase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000007217 164.0
HKD3_k127_4966355_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000002233 138.0
HKD3_k127_4966355_3 cell wall organization - - - 0.0000000000000001 92.0
HKD3_k127_4977834_0 to percent identity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 410.0
HKD3_k127_4977834_1 to GB L77117 SP Q57808 PID 1499149 percent identity - - - 0.0000000000000004111 79.0
HKD3_k127_4977834_2 COG1522 Transcriptional regulators - - - 0.00008203 51.0
HKD3_k127_4985059_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 7.058e-255 803.0
HKD3_k127_4985059_1 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.00000000000000000000000000000000000000000000000000000003812 201.0
HKD3_k127_4985059_2 Polymer-forming cytoskeletal - - - 0.0000000000000000003894 91.0
HKD3_k127_4985059_3 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00002823 53.0
HKD3_k127_505535_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 464.0
HKD3_k127_505535_1 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 458.0
HKD3_k127_505535_10 TIGRFAM mutator mutT protein K03574 - 3.6.1.55 0.000000000000000000000002473 108.0
HKD3_k127_505535_11 - - - - 0.00000000000000001548 85.0
HKD3_k127_505535_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.00000000000006365 80.0
HKD3_k127_505535_13 secreted hydrolase - - - 0.0000001446 64.0
HKD3_k127_505535_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 342.0
HKD3_k127_505535_3 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002082 291.0
HKD3_k127_505535_4 GHMP kinases C terminal K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000004362 265.0
HKD3_k127_505535_5 tRNA pseudouridine synthase D K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000799 267.0
HKD3_k127_505535_6 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000001189 253.0
HKD3_k127_505535_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000005711 194.0
HKD3_k127_505535_8 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000001653 150.0
HKD3_k127_505535_9 Domain of unknown function DUF83 K07464 - 3.1.12.1 0.0000000000000000000000000001235 121.0
HKD3_k127_5085998_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 9.302e-227 710.0
HKD3_k127_5085998_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 3.498e-195 616.0
HKD3_k127_5085998_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000001224 155.0
HKD3_k127_512240_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000001114 233.0
HKD3_k127_512240_1 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000696 93.0
HKD3_k127_512240_2 secreted hydrolase - - - 0.000000001779 71.0
HKD3_k127_512240_3 - - - - 0.00003515 55.0
HKD3_k127_5261826_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 6.898e-247 781.0
HKD3_k127_5261826_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 363.0
HKD3_k127_5261826_10 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000004667 86.0
HKD3_k127_5261826_11 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000004864 68.0
HKD3_k127_5261826_12 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179,K13276 - 3.2.1.4 0.0000003858 64.0
HKD3_k127_5261826_13 aminopeptidase activity - - - 0.000004627 60.0
HKD3_k127_5261826_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000168 52.0
HKD3_k127_5261826_2 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000005498 274.0
HKD3_k127_5261826_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000002095 224.0
HKD3_k127_5261826_4 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000009016 207.0
HKD3_k127_5261826_5 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000000005836 189.0
HKD3_k127_5261826_6 PFAM metal-dependent phosphohydrolase HD sub K06951 - - 0.0000000000000000000000000000000000000000000004973 173.0
HKD3_k127_5261826_7 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000000001048 127.0
HKD3_k127_5261826_8 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000000000004453 142.0
HKD3_k127_5261826_9 Fibronectin type III domain - - - 0.000000000000000000000000001128 125.0
HKD3_k127_5340043_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 1.515e-269 858.0
HKD3_k127_5340043_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 480.0
HKD3_k127_5340043_2 Glycerate kinase K11529 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016491,GO:0016661,GO:0016662,GO:0016740,GO:0016772,GO:0043798,GO:0044237,GO:0055114 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 324.0
HKD3_k127_5340043_3 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000009216 131.0
HKD3_k127_5340043_4 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000004047 91.0
HKD3_k127_5340043_6 Propeptide_C25 - - - 0.00000000002712 73.0
HKD3_k127_5508141_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.05e-290 917.0
HKD3_k127_5508141_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 476.0
HKD3_k127_5508141_2 OsmC-like protein K09136 - - 0.000000000000000000000000000000000000000002729 158.0
HKD3_k127_5508141_3 binds to the 23S rRNA K02921 - - 0.000000000000000000000006379 103.0
HKD3_k127_5508141_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000009192 57.0
HKD3_k127_5508141_5 Transcription factor Pcc1 K09741 - - 0.00002466 51.0
HKD3_k127_5520213_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 503.0
HKD3_k127_5520213_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 459.0
HKD3_k127_5520213_10 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000009287 70.0
HKD3_k127_5520213_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003166 286.0
HKD3_k127_5520213_3 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002271 248.0
HKD3_k127_5520213_4 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000001119 220.0
HKD3_k127_5520213_5 Desulfoferrodoxin ferrous iron-binding domain K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000000002768 190.0
HKD3_k127_5520213_6 - K07092 - - 0.0000000000000000000000000000000000000000000001647 169.0
HKD3_k127_5520213_7 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000000002162 124.0
HKD3_k127_5520213_8 Rubrerythrin - - - 0.000000000000000000000001707 106.0
HKD3_k127_5520213_9 protein conserved in archaea - - - 0.00000000000000000004086 93.0
HKD3_k127_5532221_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 586.0
HKD3_k127_5532221_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000001913 137.0
HKD3_k127_5532221_2 transcriptional regulator K03719 - - 0.000001011 57.0
HKD3_k127_553283_0 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 561.0
HKD3_k127_553283_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000001494 75.0
HKD3_k127_5544046_0 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008891 230.0
HKD3_k127_5544046_1 transcription regulator activity - - - 0.0000000000000000000000000000000000000000004765 164.0
HKD3_k127_5544046_2 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 0.0000000000000000000000000002312 130.0
HKD3_k127_5544046_3 LamG domain protein jellyroll fold domain protein K03418,K07151 - 2.4.99.18,3.5.1.56 0.00000000004825 72.0
HKD3_k127_5544046_4 - - - - 0.000001704 52.0
HKD3_k127_5544046_5 - - - - 0.00003002 48.0
HKD3_k127_5544046_6 alpha-L-arabinofuranosidase - - - 0.0001746 44.0
HKD3_k127_5563481_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 483.0
HKD3_k127_5563481_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 331.0
HKD3_k127_5563481_2 PFAM Glycosyl transferase family 2 - - - 0.00000002161 57.0
HKD3_k127_5671250_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000001076 173.0
HKD3_k127_5671250_1 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.0000000000000000006318 90.0
HKD3_k127_5671250_2 - - - - 0.00002189 53.0
HKD3_k127_5688430_0 transferase activity, transferring glycosyl groups K05889 - 1.1.2.6 0.0000000000000000000000000000001141 144.0
HKD3_k127_5688430_1 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000003253 121.0
HKD3_k127_5688430_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000002973 64.0
HKD3_k127_571_0 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 425.0
HKD3_k127_571_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
HKD3_k127_571_2 Abc transporter K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000633 266.0
HKD3_k127_571_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000006335 207.0
HKD3_k127_571_4 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000002554 172.0
HKD3_k127_571_5 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000141 156.0
HKD3_k127_571_6 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000306 96.0
HKD3_k127_571_7 - - - - 0.00000000000003759 74.0
HKD3_k127_571_8 Peptidase family C25 - - - 0.00000001656 67.0
HKD3_k127_571_9 helix_turn_helix ASNC type K03719 - - 0.00007398 52.0
HKD3_k127_5786433_0 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 460.0
HKD3_k127_5786433_1 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009204 273.0
HKD3_k127_5786433_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000005978 178.0
HKD3_k127_5786433_3 dihydromethanopterin reductase activity K00176,K06411,K12527 - 1.2.7.3,1.97.1.9 0.0000000000000005346 81.0
HKD3_k127_5841631_0 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 445.0
HKD3_k127_5841631_1 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.000000000000000000000000000000000000000000000000000000000000001641 227.0
HKD3_k127_5841631_2 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000000008039 182.0
HKD3_k127_5841631_3 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000004852 119.0
HKD3_k127_586840_0 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 366.0
HKD3_k127_586840_1 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000002262 186.0
HKD3_k127_586840_2 Belongs to the UPF0178 family - - - 0.00000000000000000000000000000000000000000005628 163.0
HKD3_k127_586840_3 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000002473 127.0
HKD3_k127_5910220_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 364.0
HKD3_k127_5910220_1 PFAM HD domain K03698 - - 0.00000000000000000000000000000000000000000000000000000000007269 216.0
HKD3_k127_5968075_0 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 435.0
HKD3_k127_5968075_1 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 364.0
HKD3_k127_5968075_2 cyclohydrolase K01746 - 4.3.1.4 0.0000000000000000000000000000000000000000000000000002515 193.0
HKD3_k127_5968075_3 PFAM HhH-GPD family protein K07457 - - 0.000000000000000000000000001857 113.0
HKD3_k127_5978323_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.392e-250 801.0
HKD3_k127_5978323_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 616.0
HKD3_k127_5978323_2 Psort location Cytoplasmic, score K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 601.0
HKD3_k127_5978323_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 371.0
HKD3_k127_5978323_4 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 349.0
HKD3_k127_5978323_5 metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004855 264.0
HKD3_k127_5978323_6 PFAM metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000002227 205.0
HKD3_k127_5978323_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000131 127.0
HKD3_k127_5978323_8 amp-dependent synthetase and ligase - - - 0.0000003554 63.0
HKD3_k127_5978323_9 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0004779 51.0
HKD3_k127_5997270_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 296.0
HKD3_k127_5998075_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 469.0
HKD3_k127_5998075_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 366.0
HKD3_k127_5998075_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 351.0
HKD3_k127_5998075_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004708 269.0
HKD3_k127_5998075_4 Signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000003143 125.0
HKD3_k127_5998075_5 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000005539 116.0
HKD3_k127_5998075_6 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000002606 112.0
HKD3_k127_6002307_0 - K03561,K12287 - - 0.0000000000000000000000000000000000000000031 177.0
HKD3_k127_6002307_1 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.0000000000000000000000006235 121.0
HKD3_k127_6002307_2 Zinc metalloprotease (Elastase) K08603,K20273 - 3.4.24.27 0.0000134 58.0
HKD3_k127_6002307_3 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000139 54.0
HKD3_k127_6042726_0 Pfam:DUF650 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 369.0
HKD3_k127_6042726_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000192 227.0
HKD3_k127_6042726_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000001961 178.0
HKD3_k127_6056522_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000112 271.0
HKD3_k127_6056522_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003475 255.0
HKD3_k127_6084313_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 473.0
HKD3_k127_6084313_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 409.0
HKD3_k127_6084313_10 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000001797 180.0
HKD3_k127_6084313_11 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000003284 175.0
HKD3_k127_6084313_12 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000004098 158.0
HKD3_k127_6084313_13 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000002192 157.0
HKD3_k127_6084313_14 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000007896 102.0
HKD3_k127_6084313_15 PFAM glutaredoxin - - - 0.00000000000000000005206 93.0
HKD3_k127_6084313_16 Lrp/AsnC ligand binding domain - - - 0.0000000000000000002035 90.0
HKD3_k127_6084313_17 PFAM regulatory protein, ArsR - - - 0.000000000000000005673 93.0
HKD3_k127_6084313_18 ABC-2 type transporter K01992 - - 0.00000000000001467 81.0
HKD3_k127_6084313_19 Uncharacterised protein - - - 0.00000000001028 78.0
HKD3_k127_6084313_2 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 365.0
HKD3_k127_6084313_20 - - - - 0.000000001991 71.0
HKD3_k127_6084313_21 - - - - 0.00000606 50.0
HKD3_k127_6084313_22 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0002559 44.0
HKD3_k127_6084313_3 TIGRFAM ribosomal RNA small subunit methyltransferase RsmB K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 360.0
HKD3_k127_6084313_4 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 306.0
HKD3_k127_6084313_5 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002005 289.0
HKD3_k127_6084313_6 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000005989 267.0
HKD3_k127_6084313_7 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000002715 259.0
HKD3_k127_6084313_8 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001801 228.0
HKD3_k127_6084313_9 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000006534 198.0
HKD3_k127_6158150_0 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000001219 237.0
HKD3_k127_6158150_1 amino acid activation for nonribosomal peptide biosynthetic process K01113 - 3.1.3.1 0.000000000000000000000000000000000000000000000009432 194.0
HKD3_k127_6158150_2 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.00000000000000000000000000000000000002566 163.0
HKD3_k127_6158150_3 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.00000000000000000000000002127 125.0
HKD3_k127_6158150_4 Transglutaminase/protease-like homologues - - - 0.00000000001862 74.0
HKD3_k127_6158150_5 Right handed beta helix region - - - 0.00000000001924 76.0
HKD3_k127_6158150_6 cell wall organization - - - 0.0000003972 62.0
HKD3_k127_6158150_7 PFAM PKD domain containing protein - - - 0.0000005043 63.0
HKD3_k127_6355139_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000004244 230.0
HKD3_k127_6362759_0 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 478.0
HKD3_k127_6362759_1 PFAM FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 351.0
HKD3_k127_6362759_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000001148 140.0
HKD3_k127_6362759_3 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000001372 105.0
HKD3_k127_6362759_4 Participates in transcription termination K02600 - - 0.000000000000000000001394 97.0
HKD3_k127_6362759_5 PFAM Glycosyl transferase family 2 - - - 0.0002817 44.0
HKD3_k127_6394751_0 Amino acid permease - - - 1.436e-271 850.0
HKD3_k127_6394751_1 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000001024 175.0
HKD3_k127_6394751_2 PFAM Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000004858 192.0
HKD3_k127_6394751_3 - - - - 0.00000000000000000004264 93.0
HKD3_k127_6394751_4 Belongs to the peptidase S8 family K03561,K12287,K20276 - - 0.0000000001727 75.0
HKD3_k127_6394751_5 Belongs to the carbamoyltransferase HypF family K04656 - - 0.0000000003016 65.0
HKD3_k127_6394751_6 outer membrane autotransporter barrel domain - - - 0.000000001566 72.0
HKD3_k127_6394751_7 protein kinase activity - - - 0.00000004834 61.0
HKD3_k127_6394751_8 TIGRFAM YD repeat protein - - - 0.0000007066 61.0
HKD3_k127_6394751_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00009206 56.0
HKD3_k127_6407566_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 3.528e-194 615.0
HKD3_k127_6434174_0 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001694 254.0
HKD3_k127_6434174_1 Belongs to the peptidase S8 family K01342,K14645 - 3.4.21.62 0.00000000000000000003345 103.0
HKD3_k127_6434174_2 cell redox homeostasis K17264 GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0005793,GO:0006457,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006986,GO:0008150,GO:0008152,GO:0009100,GO:0009986,GO:0009987,GO:0010033,GO:0012505,GO:0015036,GO:0015037,GO:0016020,GO:0016192,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0019538,GO:0019725,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0031984,GO:0032940,GO:0033554,GO:0034774,GO:0034976,GO:0035580,GO:0035966,GO:0036230,GO:0042119,GO:0042175,GO:0042221,GO:0042581,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045454,GO:0046903,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055114,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0097708,GO:0098827,GO:0099503,GO:0140096,GO:1901135,GO:1901564 - 0.000000004584 62.0
HKD3_k127_6434174_3 Bacterial pre-peptidase C-terminal domain - - - 0.00000121 62.0
HKD3_k127_6490482_0 PFAM Aldehyde dehydrogenase K00294 - 1.2.1.88 2.327e-209 663.0
HKD3_k127_6490482_1 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 423.0
HKD3_k127_6490482_2 Intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000007489 241.0
HKD3_k127_6490482_3 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000002806 241.0
HKD3_k127_6490482_4 Thioredoxin - - - 0.00000000000000000000000000000000001567 139.0
HKD3_k127_6490482_5 Universal stress protein - - - 0.0000000000000000000000000001217 120.0
HKD3_k127_6490482_6 response to heat - - - 0.000000000000000000000000002268 114.0
HKD3_k127_6490482_7 low-complexity proteins - - - 0.0000005607 57.0
HKD3_k127_6503639_0 flavodoxin nitric oxide synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 429.0
HKD3_k127_6503639_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 420.0
HKD3_k127_6503639_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 377.0
HKD3_k127_6503639_3 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 342.0
HKD3_k127_6503639_4 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000008834 217.0
HKD3_k127_6503639_5 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000009962 64.0
HKD3_k127_6521851_0 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 2.118e-241 752.0
HKD3_k127_6521851_1 PFAM AMP-dependent synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 323.0
HKD3_k127_6521851_2 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000004055 194.0
HKD3_k127_6521851_3 homolog of PrgY (pheromone shutdown protein) - - - 0.000000000000000000000000000000000003556 146.0
HKD3_k127_6554680_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 434.0
HKD3_k127_6554680_1 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 394.0
HKD3_k127_6554680_2 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.000000000000000000000000000000002754 133.0
HKD3_k127_6563_0 Cation transporter/ATPase, N-terminus K01537 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 518.0
HKD3_k127_6563_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 494.0
HKD3_k127_6563_2 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0042802,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000009353 48.0
HKD3_k127_657032_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.336e-291 921.0
HKD3_k127_657032_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.315e-209 689.0
HKD3_k127_657032_10 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000004632 267.0
HKD3_k127_657032_11 TIGRFAM geranylgeranyl reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004787 266.0
HKD3_k127_657032_12 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003278 244.0
HKD3_k127_657032_13 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000006196 224.0
HKD3_k127_657032_14 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000008914 194.0
HKD3_k127_657032_15 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000001944 183.0
HKD3_k127_657032_16 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000001074 181.0
HKD3_k127_657032_17 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000005649 165.0
HKD3_k127_657032_18 Putative small multi-drug export protein - - - 0.000000000000000000000000000001237 126.0
HKD3_k127_657032_19 Vacuolar protein sorting-associated protein 62 - GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0006605,GO:0006623,GO:0006810,GO:0006886,GO:0007034,GO:0008104,GO:0008150,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0031090,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072594,GO:0072665,GO:0072666,GO:0098588,GO:0098805,GO:0098852 - 0.00000000000004623 85.0
HKD3_k127_657032_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 586.0
HKD3_k127_657032_20 Caspase domain - - - 0.00000001509 65.0
HKD3_k127_657032_21 - - - - 0.00000005701 63.0
HKD3_k127_657032_3 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 498.0
HKD3_k127_657032_4 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 440.0
HKD3_k127_657032_5 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 407.0
HKD3_k127_657032_6 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 344.0
HKD3_k127_657032_7 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 362.0
HKD3_k127_657032_8 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 302.0
HKD3_k127_657032_9 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000002953 271.0
HKD3_k127_6583697_0 Aromatic amino acid lyase K01745 - 4.3.1.3 3.096e-263 819.0
HKD3_k127_6583697_1 Urocanase C-terminal domain K01712 - 4.2.1.49 1.38e-229 724.0
HKD3_k127_6583697_2 Radical SAM domain protein K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 466.0
HKD3_k127_6583697_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
HKD3_k127_6583697_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000003375 246.0
HKD3_k127_6583697_5 TIGRFAM Small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000006413 154.0
HKD3_k127_6583697_6 Peptidase family M28 - - - 0.0000000000000000000000001367 121.0
HKD3_k127_6583697_7 snRNP Sm proteins K04796 - - 0.00000000000001192 74.0
HKD3_k127_6589673_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000005128 116.0
HKD3_k127_6589673_1 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000009961 74.0
HKD3_k127_6603870_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004646 268.0
HKD3_k127_6603870_1 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.0000000000000000000000004376 109.0
HKD3_k127_6603870_2 amine dehydrogenase activity - - - 0.0000000006011 71.0
HKD3_k127_6627265_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 493.0
HKD3_k127_6627265_1 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 457.0
HKD3_k127_6627265_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 361.0
HKD3_k127_6627265_3 Clp protease K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 338.0
HKD3_k127_6627265_4 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 291.0
HKD3_k127_6627265_5 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000723 288.0
HKD3_k127_6649373_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 312.0
HKD3_k127_6649373_1 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000005941 166.0
HKD3_k127_6649373_2 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 - 3.4.19.3 0.000000000000000000000000000001622 128.0
HKD3_k127_6649373_3 aminopeptidase activity K05994 - 3.4.11.10 0.0000000000000000000001591 111.0
HKD3_k127_6649373_4 Propeptide_C25 - - - 0.00000000000000001388 97.0
HKD3_k127_6649373_5 Belongs to the peptidase S8 family K20276 - - 0.0000000000004 83.0
HKD3_k127_6662790_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 441.0
HKD3_k127_6662790_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 350.0
HKD3_k127_6662790_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000005123 180.0
HKD3_k127_6662790_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000001536 132.0
HKD3_k127_6662790_4 - - - - 0.0000000000000000000000001503 112.0
HKD3_k127_6662790_5 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000001252 76.0
HKD3_k127_6678377_0 PD-(D/E)XK nuclease superfamily K07465 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 367.0
HKD3_k127_6678377_1 Papain family cysteine protease - - - 0.00000000000000000000000000000000000001342 164.0
HKD3_k127_6678377_2 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000002339 137.0
HKD3_k127_6678377_3 Belongs to the TPP enzyme family - - - 0.000000000007241 75.0
HKD3_k127_6678377_4 Peptidase family C25 - - - 0.00000000578 70.0
HKD3_k127_6678377_5 cellulase activity K01218,K12132 - 2.7.11.1,3.2.1.78 0.0003908 52.0
HKD3_k127_6698699_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.844e-255 804.0
HKD3_k127_6698699_1 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006334 457.0
HKD3_k127_6698699_10 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000001418 183.0
HKD3_k127_6698699_11 ribosomal protein S15 K02956 - - 0.0000000000000000000000000000000000000000000561 164.0
HKD3_k127_6698699_12 Belongs to the peptidase C1 family K01275 GO:0000323,GO:0001775,GO:0001906,GO:0001909,GO:0001913,GO:0002250,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0002449,GO:0002456,GO:0002460,GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004252,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0005793,GO:0005794,GO:0005798,GO:0005813,GO:0005815,GO:0005856,GO:0006508,GO:0006807,GO:0006810,GO:0006887,GO:0006888,GO:0006900,GO:0006901,GO:0006903,GO:0006915,GO:0006955,GO:0006996,GO:0007568,GO:0008047,GO:0008150,GO:0008152,GO:0008219,GO:0008233,GO:0008234,GO:0008236,GO:0009056,GO:0009057,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010467,GO:0010604,GO:0010646,GO:0010647,GO:0010941,GO:0010942,GO:0010952,GO:0012501,GO:0012505,GO:0015630,GO:0016020,GO:0016043,GO:0016050,GO:0016192,GO:0016485,GO:0016504,GO:0016505,GO:0016787,GO:0017171,GO:0019222,GO:0019538,GO:0019899,GO:0019902,GO:0022607,GO:0023051,GO:0023056,GO:0030134,GO:0030135,GO:0030141,GO:0030162,GO:0030163,GO:0030234,GO:0031090,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031404,GO:0031410,GO:0031638,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032502,GO:0032940,GO:0033116,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042176,GO:0042221,GO:0042582,GO:0042802,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043299,GO:0043312,GO:0043621,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0045732,GO:0045862,GO:0046903,GO:0046907,GO:0048193,GO:0048194,GO:0048199,GO:0048207,GO:0048208,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051087,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051603,GO:0051604,GO:0051640,GO:0051641,GO:0051648,GO:0051649,GO:0051650,GO:0051656,GO:0052547,GO:0060205,GO:0060255,GO:0061024,GO:0061134,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0071704,GO:0071840,GO:0080090,GO:0090114,GO:0097708,GO:0098588,GO:0098772,GO:0099503,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:2001233,GO:2001235 3.4.14.1 0.000000000000000000000000000025 134.0
HKD3_k127_6698699_13 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000001638 83.0
HKD3_k127_6698699_14 COG1520 FOG WD40-like repeat - - - 0.0000000000001918 83.0
HKD3_k127_6698699_15 - - - - 0.0000007855 53.0
HKD3_k127_6698699_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 430.0
HKD3_k127_6698699_3 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 416.0
HKD3_k127_6698699_4 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 328.0
HKD3_k127_6698699_5 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 324.0
HKD3_k127_6698699_6 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 298.0
HKD3_k127_6698699_7 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001805 258.0
HKD3_k127_6698699_8 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000034 229.0
HKD3_k127_6698699_9 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000006398 214.0
HKD3_k127_6719034_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000003136 254.0
HKD3_k127_6719034_1 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000359 244.0
HKD3_k127_6719034_2 PQQ enzyme repeat - - - 0.000000000000000000000000008436 127.0
HKD3_k127_6719034_3 phosphorelay signal transduction system K07658 - - 0.00000000000000000000002994 103.0
HKD3_k127_6719034_5 COG1522 Transcriptional regulators - - - 0.00001996 56.0
HKD3_k127_6738066_0 FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 369.0
HKD3_k127_6738066_1 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 357.0
HKD3_k127_6738066_2 Glycosyl hydrolases family 39 - - - 0.000000000000000000000000000000000000000004765 164.0
HKD3_k127_6738066_3 Acyl-protein synthetase, LuxE - - - 0.000000000000000000003002 106.0
HKD3_k127_6738066_4 Sterol carrier protein - - - 0.000000000003173 72.0
HKD3_k127_6738066_5 Bacterial Ig-like domain (group 3) - - - 0.00000000005198 75.0
HKD3_k127_6747415_0 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 316.0
HKD3_k127_6747415_1 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.00000000000000000000000000000000000000000000000000009704 193.0
HKD3_k127_6747415_2 NYN domain - - - 0.0000000000000000000000000000000000000000000002917 168.0
HKD3_k127_6747415_3 ArsR transcriptional regulator - - - 0.000000000000000000000000000000002232 135.0
HKD3_k127_6747415_4 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000008065 136.0
HKD3_k127_6760990_0 Belongs to the TPP enzyme family K00158 - 1.2.3.3 1.328e-212 672.0
HKD3_k127_6760990_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 295.0
HKD3_k127_6760990_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000001653 231.0
HKD3_k127_6760990_3 Peptidase family M28 K05994 - 3.4.11.10 0.000000000000000000002034 108.0
HKD3_k127_6760990_4 - - - - 0.00000000000002536 76.0
HKD3_k127_6760990_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000006473 55.0
HKD3_k127_6760990_6 - - - - 0.00000397 49.0
HKD3_k127_6793657_0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 427.0
HKD3_k127_6793657_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 307.0
HKD3_k127_6793657_2 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000002466 265.0
HKD3_k127_6793657_3 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000444 239.0
HKD3_k127_6793657_4 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000006646 213.0
HKD3_k127_6793657_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000001413 171.0
HKD3_k127_6793657_6 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000001778 143.0
HKD3_k127_6793657_7 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000005663 87.0
HKD3_k127_6793657_8 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000005125 93.0
HKD3_k127_6816535_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147,K22465 - 4.1.99.17,4.1.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 499.0
HKD3_k127_6816535_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 381.0
HKD3_k127_6816535_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.000000000000000000001884 98.0
HKD3_k127_6816535_3 Polymorphic membrane protein, Chlamydia - - - 0.000001278 59.0
HKD3_k127_6817953_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.579e-269 850.0
HKD3_k127_6817953_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 4.789e-197 634.0
HKD3_k127_6817953_2 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 319.0
HKD3_k127_6817953_3 Belongs to the UPF0200 family - - - 0.000000000000000000000000000000000000000000000007096 177.0
HKD3_k127_6817953_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000001103 172.0
HKD3_k127_6817953_5 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000000000001124 123.0
HKD3_k127_6817953_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000001068 89.0
HKD3_k127_6841978_0 Psort location Extracellular, score 9.64 - - - 0.000000000000000000000000000000000000000000000000000000003389 207.0
HKD3_k127_6841978_1 PFAM NHL repeat containing protein - - - 0.000000000000000000003709 106.0
HKD3_k127_6841978_2 helix_turn_helix ASNC type K03719 - - 0.000006619 55.0
HKD3_k127_6848623_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003152 269.0
HKD3_k127_6848623_1 PQ loop repeat K15383 - - 0.00000000000000000001123 94.0
HKD3_k127_6848623_2 Radical SAM - - - 0.0000000007864 70.0
HKD3_k127_6848623_3 Methyltransferase domain - - - 0.000000003758 65.0
HKD3_k127_6848623_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000002202 64.0
HKD3_k127_6887737_0 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000001323 119.0
HKD3_k127_6887737_1 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.00000000000005456 74.0
HKD3_k127_6972101_0 PFAM elongation factor Tu, domain 2 protein - - - 0.00000000000000000000000000000000000000000000000000003734 199.0
HKD3_k127_6972101_1 Flavodoxin - - - 0.00000000000000000000000000000000000000000000003426 175.0
HKD3_k127_6972101_2 Domain of unknown function (DUF4382) - - - 0.00001109 55.0
HKD3_k127_7005812_0 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000007367 207.0
HKD3_k127_7005812_1 deoxyribonuclease I activity K06131,K06915 - - 0.00000000000000000000000000000000000001168 155.0
HKD3_k127_7005812_2 Rhomboid family - - - 0.000000000000000000000005569 113.0
HKD3_k127_7045184_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1449.0
HKD3_k127_7045184_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 607.0
HKD3_k127_7045184_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 440.0
HKD3_k127_7045184_3 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 319.0
HKD3_k127_7045184_4 calcium proton exchanger K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002506 290.0
HKD3_k127_7045184_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000263 274.0
HKD3_k127_7045184_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000001096 232.0
HKD3_k127_7045184_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000001048 179.0
HKD3_k127_7045184_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000009195 132.0
HKD3_k127_7045184_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000003662 60.0
HKD3_k127_7062133_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 381.0
HKD3_k127_7062133_1 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.0000000000000000000000000002898 125.0
HKD3_k127_7062133_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000006321 113.0
HKD3_k127_7062133_3 phosphoesterase RecJ domain protein - - - 0.0001233 46.0
HKD3_k127_7073667_0 Proto-chlorophyllide reductase 57 kD subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000838 266.0
HKD3_k127_7073667_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000001073 188.0
HKD3_k127_7073667_2 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000000000000000000003249 116.0
HKD3_k127_7073667_3 ABC transporter K01990 - - 0.000000000000000000000004391 109.0
HKD3_k127_7143886_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 476.0
HKD3_k127_7143886_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 358.0
HKD3_k127_7143886_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 299.0
HKD3_k127_7143886_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000004741 240.0
HKD3_k127_7143886_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives - - - 0.0000000000000000001495 93.0
HKD3_k127_7143886_5 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000004212 76.0
HKD3_k127_7148409_0 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 334.0
HKD3_k127_7148409_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 297.0
HKD3_k127_7148409_2 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547,K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004763 280.0
HKD3_k127_7148409_3 Phage integrase, N-terminal SAM-like domain K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0002737 51.0
HKD3_k127_7170390_0 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000358 192.0
HKD3_k127_7170390_1 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000006703 86.0
HKD3_k127_7170390_2 PFAM molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.0000000004727 63.0
HKD3_k127_7170390_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0000002124 61.0
HKD3_k127_7170390_4 PFAM transglutaminase domain protein - - - 0.0007594 51.0
HKD3_k127_7170907_0 Methionine biosynthesis protein MetW - - - 0.000000000000000000006592 104.0
HKD3_k127_7170907_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000003047 70.0
HKD3_k127_7170907_2 amino acid activation for nonribosomal peptide biosynthetic process K01183 - 3.2.1.14 0.0002096 46.0
HKD3_k127_7198664_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004325 554.0
HKD3_k127_7198664_1 helicase superfamily c-terminal domain K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 479.0
HKD3_k127_7198664_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 417.0
HKD3_k127_7198664_3 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000012 208.0
HKD3_k127_7198664_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00009549 48.0
HKD3_k127_7212003_0 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 395.0
HKD3_k127_7212003_1 Belongs to the peptidase S16 family K06870 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 317.0
HKD3_k127_7212003_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004966 232.0
HKD3_k127_7212003_3 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000305 222.0
HKD3_k127_7212003_4 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.00000000000000000000000000000000000000000000000000000006115 209.0
HKD3_k127_7212003_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000006905 171.0
HKD3_k127_7212003_6 Pectate lyase - - - 0.00002112 57.0
HKD3_k127_7227037_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 576.0
HKD3_k127_7227037_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 403.0
HKD3_k127_7227037_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000005633 210.0
HKD3_k127_7227037_3 Evidence 5 No homology to any previously reported sequences K01361,K13277 - 3.4.21.96 0.00000000000000000000000000000000000000000000003831 185.0
HKD3_k127_7227037_4 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000944 111.0
HKD3_k127_7227037_5 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000004614 101.0
HKD3_k127_7227037_6 Protein of unknown function (DUF1349) - - - 0.000000000000000159 92.0
HKD3_k127_7227037_7 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0004317 43.0
HKD3_k127_7227037_8 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0008002 42.0
HKD3_k127_7304675_0 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 271.0
HKD3_k127_7304675_1 methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000195 198.0
HKD3_k127_7304675_2 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.00000000000000000000000000000000000000000000000938 184.0
HKD3_k127_7383695_0 response regulator, receiver K07668,K07669 - - 0.0000000000000000000000000000000005805 134.0
HKD3_k127_7383695_1 KaiC - - - 0.000000000000000000000000002001 122.0
HKD3_k127_7383695_2 Circadian clock protein KaiC - - - 0.000000000000000000002623 104.0
HKD3_k127_7383695_3 methyltransferase activity - - - 0.00000000000007867 78.0
HKD3_k127_7424043_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000004509 57.0
HKD3_k127_7457240_0 - - - - 0.000000000000000000000000000000000000000000000000000000006075 203.0
HKD3_k127_7457240_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.0000000000000000000000000000000000000000003724 162.0
HKD3_k127_7457240_3 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.00000000000003936 75.0
HKD3_k127_7457240_4 - - - - 0.00004516 48.0
HKD3_k127_7471114_0 - - - - 0.000008735 54.0
HKD3_k127_7471114_1 Lrp/AsnC ligand binding domain - - - 0.0008836 48.0
HKD3_k127_7492691_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000003335 229.0
HKD3_k127_7492691_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000003265 210.0
HKD3_k127_7492691_2 FMN binding - - - 0.0000000005351 68.0
HKD3_k127_7534762_0 peptidase activity, acting on L-amino acid peptides K07752 - 3.4.17.22 0.00000000000000000000000000000000000000000000000000000000000001329 241.0
HKD3_k127_7534762_1 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000005535 190.0
HKD3_k127_7534762_2 PFAM nucleoside H symporter K05820 - - 0.0000000000000000000000000000006673 124.0
HKD3_k127_7534762_3 Collagen triple helix repeat (20 copies) - - - 0.00000000000000000009079 103.0
HKD3_k127_7534762_4 Archaeal Type IV pilin, N-terminal - - - 0.00000000000000003415 96.0
HKD3_k127_7534762_5 Lactonase, 7-bladed beta-propeller - - - 0.00000002412 66.0
HKD3_k127_7564203_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006939 295.0
HKD3_k127_7564203_1 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002319 281.0
HKD3_k127_7564203_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002397 238.0
HKD3_k127_7564203_3 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000003344 191.0
HKD3_k127_7564203_4 DNA polymerase K02347 - - 0.0000000000000000000000000000000001251 136.0
HKD3_k127_7564203_5 Peptidase family M28 - - - 0.0000000000000000000000000000001785 141.0
HKD3_k127_7564203_6 Winged helix DNA-binding domain (DUF1495) K09745 - - 0.00000000000001898 78.0
HKD3_k127_7567660_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 400.0
HKD3_k127_7567660_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 380.0
HKD3_k127_7567660_10 aminopeptidase activity - - - 0.0000003119 63.0
HKD3_k127_7567660_11 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000005259 62.0
HKD3_k127_7567660_12 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000007455 61.0
HKD3_k127_7567660_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 377.0
HKD3_k127_7567660_3 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003578 279.0
HKD3_k127_7567660_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000007375 225.0
HKD3_k127_7567660_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000004497 218.0
HKD3_k127_7567660_6 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000005291 197.0
HKD3_k127_7567660_7 Pas domain - - - 0.000000000000000000000000000000000000000000000009625 183.0
HKD3_k127_7567660_8 phosphorelay signal transduction system - - - 0.000000000000000000001141 99.0
HKD3_k127_7567660_9 Peptidase, M28 - - - 0.00000000000000000007119 103.0
HKD3_k127_7649118_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.25e-214 683.0
HKD3_k127_7649118_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 1.907e-195 618.0
HKD3_k127_7649118_10 - - - - 0.0000000000000000000000000997 107.0
HKD3_k127_7649118_11 Lrp/AsnC ligand binding domain - - - 0.000000000000000000059 91.0
HKD3_k127_7649118_12 parallel beta-helix repeat K03671 - - 0.000000002944 68.0
HKD3_k127_7649118_13 - - - - 0.0000001573 57.0
HKD3_k127_7649118_2 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 550.0
HKD3_k127_7649118_3 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 503.0
HKD3_k127_7649118_4 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 429.0
HKD3_k127_7649118_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000003368 203.0
HKD3_k127_7649118_6 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000005349 173.0
HKD3_k127_7649118_7 Patched family K07003 - - 0.00000000000000000000000000000000000000000000006256 185.0
HKD3_k127_7649118_8 regulator of amino acid metabolism K07103 - - 0.000000000000000000000000000000000002035 143.0
HKD3_k127_7649118_9 Lrp/AsnC ligand binding domain - - - 0.00000000000000000000000000000002537 126.0
HKD3_k127_767711_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 487.0
HKD3_k127_767711_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008064 357.0
HKD3_k127_767711_10 - - - - 0.0000000000000000000000006366 108.0
HKD3_k127_767711_11 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000005311 74.0
HKD3_k127_767711_2 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 352.0
HKD3_k127_767711_3 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 301.0
HKD3_k127_767711_4 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000003567 155.0
HKD3_k127_767711_5 4Fe-4S binding domain protein - - - 0.000000000000000000000000000000000000002816 157.0
HKD3_k127_767711_6 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.00000000000000000000000000000000007301 146.0
HKD3_k127_767711_7 Uncharacterised protein family (UPF0179) K09730 - - 0.000000000000000000000000000000000816 135.0
HKD3_k127_767711_8 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000001338 146.0
HKD3_k127_767711_9 Papain family cysteine protease - - - 0.00000000000000000000000000001899 126.0
HKD3_k127_7727745_0 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000000000000002208 235.0
HKD3_k127_7727745_1 SPTR Genome sequencing data, contig C243 - - - 0.000004882 55.0
HKD3_k127_7760219_0 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 410.0
HKD3_k127_7760219_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000195 213.0
HKD3_k127_7760219_2 PFAM Activator of Hsp90 ATPase - - - 0.000000000000000000000000000000000000000003917 160.0
HKD3_k127_7760219_3 glucosylceramidase activity - - - 0.00000000000000000000000002467 111.0
HKD3_k127_7760219_4 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000761 112.0
HKD3_k127_7760219_5 ChaB K06197 - - 0.0000000000000002054 81.0
HKD3_k127_7760219_6 Kelch repeat - - - 0.0000000000000005664 90.0
HKD3_k127_7760219_7 Ferritin-like domain - - - 0.00000001169 67.0
HKD3_k127_7760219_8 Cadherin-like beta sandwich domain - - - 0.0000003906 61.0
HKD3_k127_7760219_9 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000007043 57.0
HKD3_k127_7773029_0 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000002018 244.0
HKD3_k127_7773029_1 transcriptional - - - 0.00000000000000000000000000002342 119.0
HKD3_k127_78_0 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000002341 164.0
HKD3_k127_78_1 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000002014 148.0
HKD3_k127_78_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000001227 147.0
HKD3_k127_78_3 - - - - 0.000000000000117 84.0
HKD3_k127_78_4 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000004947 66.0
HKD3_k127_78_5 Winged helix-turn-helix domain (DUF2582) - - - 0.0000001293 58.0
HKD3_k127_78_6 Winged helix-turn-helix domain (DUF2582) - - - 0.0000005678 57.0
HKD3_k127_78_7 Winged helix-turn-helix domain (DUF2582) - - - 0.000001436 56.0
HKD3_k127_78_8 Winged helix-turn-helix domain (DUF2582) - - - 0.00001018 53.0
HKD3_k127_7864689_0 PKD domain K19668,K20850 - 3.2.1.157,3.2.1.91 0.0000000000000000001247 104.0
HKD3_k127_7864689_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000001414 81.0
HKD3_k127_7896456_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 293.0
HKD3_k127_7896456_1 Diphthamide K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003983 284.0
HKD3_k127_7896456_10 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000009005 81.0
HKD3_k127_7896456_11 - - - - 0.0000000000000003243 89.0
HKD3_k127_7896456_12 protein conserved in archaea K09723 - - 0.0000000002382 69.0
HKD3_k127_7896456_13 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000002365 59.0
HKD3_k127_7896456_2 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000455 254.0
HKD3_k127_7896456_3 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000002278 232.0
HKD3_k127_7896456_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002256 235.0
HKD3_k127_7896456_5 - - - - 0.0000000000000000000000000000000000000000000000000000006331 202.0
HKD3_k127_7896456_6 phosphonoacetaldehyde hydrolase activity K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000002857 185.0
HKD3_k127_7896456_7 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000001797 178.0
HKD3_k127_7896456_8 Binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000004451 143.0
HKD3_k127_7896456_9 AAA domain K07028 - - 0.0000000000000000000000000007509 119.0
HKD3_k127_7939668_0 aminopeptidase K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 427.0
HKD3_k127_7941927_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007853 254.0
HKD3_k127_7941927_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000001355 158.0
HKD3_k127_7941927_2 PFAM thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000005767 138.0
HKD3_k127_7941927_3 TIGRFAM cytidyltransferase-related domain K02201 - 2.7.7.3 0.000000000000000000000000000000003255 134.0
HKD3_k127_7941927_4 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000009868 111.0
HKD3_k127_7941927_5 - - - - 0.000000000000411 72.0
HKD3_k127_7941927_6 Protein of unknown function (DUF998) - - - 0.0000000000826 70.0
HKD3_k127_7941927_7 Papain family cysteine protease - - - 0.000008113 59.0
HKD3_k127_7941927_8 DNA polymerase K02320 GO:0000003,GO:0000228,GO:0000278,GO:0000428,GO:0000726,GO:0000731,GO:0000734,GO:0000781,GO:0000784,GO:0000785,GO:0000790,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003682,GO:0003688,GO:0003690,GO:0003697,GO:0003824,GO:0003887,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005658,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006270,GO:0006271,GO:0006272,GO:0006273,GO:0006278,GO:0006279,GO:0006281,GO:0006302,GO:0006303,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007530,GO:0007531,GO:0007533,GO:0007534,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0022402,GO:0022413,GO:0022414,GO:0022616,GO:0030154,GO:0030880,GO:0030894,GO:0031974,GO:0031981,GO:0032502,GO:0032505,GO:0032774,GO:0032991,GO:0032993,GO:0033260,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035822,GO:0035861,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0044786,GO:0045165,GO:0046483,GO:0048869,GO:0050896,GO:0051321,GO:0051716,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0090734,GO:0097159,GO:0098687,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902292,GO:1902295,GO:1902315,GO:1902318,GO:1902494,GO:1902969,GO:1902975,GO:1902981,GO:1903046,GO:1903047,GO:1990234,GO:1990837 2.7.7.7 0.000192 55.0
HKD3_k127_7944449_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 2.425e-223 708.0
HKD3_k127_7944449_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 395.0
HKD3_k127_7944449_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000002729 180.0
HKD3_k127_7944449_3 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000001926 159.0
HKD3_k127_7944449_4 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001483 90.0
HKD3_k127_7944449_5 Peptidase family C25, C terminal ig-like domain K08589 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37 0.0000000000000001747 94.0
HKD3_k127_7944449_6 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.00000000004478 63.0
HKD3_k127_7944449_7 Nicotianamine synthase protein - - - 0.0000001104 61.0
HKD3_k127_7968063_0 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 296.0
HKD3_k127_7968063_1 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.00000000000000000000000000003464 127.0
HKD3_k127_7968063_2 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.000000001533 68.0
HKD3_k127_7968063_3 - - - - 0.000000003767 59.0
HKD3_k127_7968063_4 N-terminal 7TM region of histidine kinase - - - 0.00000643 59.0
HKD3_k127_7968063_5 CAP_GLY K10421,K10422,K10423 GO:0000226,GO:0000278,GO:0000775,GO:0000776,GO:0001578,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005768,GO:0005794,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0005874,GO:0005875,GO:0005876,GO:0005881,GO:0005882,GO:0006810,GO:0006886,GO:0006996,GO:0007010,GO:0007017,GO:0007026,GO:0007049,GO:0007275,GO:0007349,GO:0007399,GO:0008017,GO:0008092,GO:0008104,GO:0008150,GO:0008270,GO:0009653,GO:0009987,GO:0010638,GO:0010639,GO:0010720,GO:0010975,GO:0010976,GO:0012505,GO:0015031,GO:0015630,GO:0015631,GO:0015833,GO:0016043,GO:0017022,GO:0022008,GO:0030141,GO:0030154,GO:0030424,GO:0030425,GO:0030426,GO:0030427,GO:0031110,GO:0031111,GO:0031112,GO:0031113,GO:0031114,GO:0031116,GO:0031334,GO:0031344,GO:0031346,GO:0031410,GO:0031967,GO:0031975,GO:0031982,GO:0032036,GO:0032271,GO:0032273,GO:0032501,GO:0032502,GO:0032594,GO:0032596,GO:0032886,GO:0032991,GO:0033036,GO:0033043,GO:0033267,GO:0034613,GO:0035371,GO:0036477,GO:0042599,GO:0042802,GO:0042803,GO:0042886,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043242,GO:0043244,GO:0043254,GO:0044087,GO:0044089,GO:0044295,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0044860,GO:0044861,GO:0045111,GO:0045169,GO:0045184,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0046872,GO:0046907,GO:0046914,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048646,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050773,GO:0050789,GO:0050793,GO:0050794,GO:0051010,GO:0051094,GO:0051128,GO:0051129,GO:0051130,GO:0051179,GO:0051234,GO:0051239,GO:0051240,GO:0051493,GO:0051494,GO:0051495,GO:0051641,GO:0051649,GO:0051668,GO:0051960,GO:0051962,GO:0060284,GO:0061024,GO:0065007,GO:0070507,GO:0070727,GO:0070853,GO:0070854,GO:0071702,GO:0071705,GO:0071840,GO:0072657,GO:0090150,GO:0097447,GO:0097458,GO:0097708,GO:0098687,GO:0099080,GO:0099081,GO:0099503,GO:0099512,GO:0099513,GO:0120025,GO:0120035,GO:0120038,GO:0150034,GO:1900006,GO:1901588,GO:1901879,GO:1901880,GO:1902903,GO:1902904,GO:1902905,GO:1903044,GO:1990752,GO:1990778,GO:2000026 - 0.0001532 55.0
HKD3_k127_7981397_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.322e-296 934.0
HKD3_k127_7981397_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 1.299e-204 656.0
HKD3_k127_7981397_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 511.0
HKD3_k127_800231_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000004714 225.0
HKD3_k127_800231_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000006191 161.0
HKD3_k127_800231_2 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000009796 111.0
HKD3_k127_800231_3 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000001563 120.0
HKD3_k127_800231_4 FAD linked oxidase domain protein - - - 0.00000000000000000000000004726 117.0
HKD3_k127_800231_5 Helix-turn-helix XRE-family like proteins K07729 - - 0.00000000000000000000000008308 108.0
HKD3_k127_800231_6 SCP-2 sterol transfer family - - - 0.0006279 48.0
HKD3_k127_8007485_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 2.371e-273 852.0
HKD3_k127_8007485_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 268.0
HKD3_k127_8007485_2 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000006337 239.0
HKD3_k127_8007485_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001414 229.0
HKD3_k127_8007485_4 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
HKD3_k127_8007485_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000000001505 121.0
HKD3_k127_8007485_6 agmatine deiminase activity K08589,K10536,K20276 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37,3.5.3.12 0.00000000000000001279 97.0
HKD3_k127_8007485_7 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000002867 76.0
HKD3_k127_8066345_0 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003092 263.0
HKD3_k127_8066345_1 - - - - 0.00000000000000000000000000000000002768 142.0
HKD3_k127_8066345_2 Right handed beta helix region - - - 0.00003438 51.0
HKD3_k127_8079222_0 FG-GAP repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 399.0
HKD3_k127_8079222_1 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000009058 178.0
HKD3_k127_8079222_2 Caspase domain - - - 0.00000000000000000000000000000001335 138.0
HKD3_k127_8079222_3 thiolester hydrolase activity K01259,K06889,K21193 - 3.4.11.5 0.0000000000000000000007011 107.0
HKD3_k127_8079222_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000003378 99.0
HKD3_k127_8079222_5 Psort location Cytoplasmic, score - - - 0.00000000000000006777 90.0
HKD3_k127_8079222_6 Belongs to the peptidase S8 family - - - 0.0000000000000001772 88.0
HKD3_k127_8089891_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000208 259.0
HKD3_k127_8089891_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000006881 219.0
HKD3_k127_8089891_2 - - - - 0.0000000000000000000000000000000000000000000000000008117 193.0
HKD3_k127_8089891_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000004786 181.0
HKD3_k127_8110290_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 464.0
HKD3_k127_8110290_1 PAS fold - - - 0.0000000000000000000000000000000000000000000000002598 202.0
HKD3_k127_8110290_2 Radical SAM - - - 0.000000000000000000000000000000000000003362 156.0
HKD3_k127_8110290_3 PFAM periplasmic copper-binding - - - 0.0000000000000000000000000001988 134.0
HKD3_k127_8110290_4 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000001039 110.0
HKD3_k127_8147593_0 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008721 271.0
HKD3_k127_8147593_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000005387 178.0
HKD3_k127_8147593_2 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000209 179.0
HKD3_k127_8147593_3 protein conserved in archaea - - - 0.00000000000000001095 87.0
HKD3_k127_8147593_4 acetyltransferase - - - 0.00000000000000003433 86.0
HKD3_k127_8147593_5 Biotin-protein ligase, N terminal - - - 0.00006586 55.0
HKD3_k127_8163898_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.347e-222 705.0
HKD3_k127_8163898_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 456.0
HKD3_k127_8163898_2 GTP-binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 298.0
HKD3_k127_8163898_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000000000000000000000000000000000000004671 253.0
HKD3_k127_8163898_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000001738 218.0
HKD3_k127_8163898_5 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000707 131.0
HKD3_k127_8163898_6 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000004576 117.0
HKD3_k127_8163898_7 Protease prsW family - - - 0.000000000000000002992 93.0
HKD3_k127_8163898_8 Zn-ribbon containing protein K07163 - - 0.00000000000000047 85.0
HKD3_k127_8163898_9 Domain of unknown function (DUF4430) - - - 0.0004059 52.0
HKD3_k127_8225221_0 ABC transporter, ATP-binding protein K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 346.0
HKD3_k127_8225221_1 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001418 278.0
HKD3_k127_8225221_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001187 275.0
HKD3_k127_8225221_3 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000001242 204.0
HKD3_k127_8225221_4 AAA domain - - - 0.000000000000000000000002347 111.0
HKD3_k127_8225221_5 PFAM Fibronectin type III domain - - - 0.0000000000000000000009503 104.0
HKD3_k127_8225221_6 Peptidase C10 family - - - 0.00000000000000001212 98.0
HKD3_k127_8247789_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 407.0
HKD3_k127_8247789_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 402.0
HKD3_k127_8247789_2 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002924 286.0
HKD3_k127_8247789_3 acetyltransferase - - - 0.000000000000000000000000000000000000000003296 165.0
HKD3_k127_8247789_4 COG1668 ABC-type Na efflux pump, permease component - - - 0.00000000000000000000000000002218 128.0
HKD3_k127_8296374_0 DNA polymerase LigD polymerase domain K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000002018 234.0
HKD3_k127_8296374_1 DNA polymerase Ligase (LigD) - - - 0.0000000000000000000000000000000000000000000000000414 183.0
HKD3_k127_8296374_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.00000000000000000000000000000000000000000002748 171.0
HKD3_k127_8296374_3 protein kinase related protein - - - 0.000000000000000000000005032 117.0
HKD3_k127_8296374_4 DNA ligase K01971 - 6.5.1.1 0.000000000000001269 83.0
HKD3_k127_8302480_0 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000006727 199.0
HKD3_k127_8302480_1 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000002179 58.0
HKD3_k127_8302480_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.0000005566 61.0
HKD3_k127_8428452_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 443.0
HKD3_k127_8428452_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000972 150.0
HKD3_k127_8428452_2 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.0000000000000000000000000000000000007646 142.0
HKD3_k127_8428452_3 Protein of unknown function (DUF504) K09715 - - 0.000000000748 62.0
HKD3_k127_8428452_4 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.000000001297 70.0
HKD3_k127_8439750_0 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 324.0
HKD3_k127_8439750_1 PFAM ABC transporter related K02006,K02068,K03529,K06166,K16786,K16787 - 2.7.8.37 0.0000001543 62.0
HKD3_k127_854962_0 Helix-turn-helix XRE-family like proteins K07731 - - 0.0000000000000000000000000000000000000000000000000000000000000000002974 237.0
HKD3_k127_854962_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000002158 76.0
HKD3_k127_854962_2 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.000004537 50.0
HKD3_k127_857290_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 456.0
HKD3_k127_857290_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 391.0
HKD3_k127_857290_2 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000009069 268.0
HKD3_k127_857290_3 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 244.0
HKD3_k127_857290_4 UDP binding domain K00012 - 1.1.1.22 0.000000000000003727 79.0
HKD3_k127_8585307_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 481.0
HKD3_k127_8585307_1 Pfam:DUF137 K09722 - 6.3.2.36 0.00000000000000000000000000000000000000000000000000008682 192.0
HKD3_k127_8585307_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000001342 202.0
HKD3_k127_8635944_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000001466 207.0
HKD3_k127_8635944_1 - - - - 0.000000000000000002767 93.0
HKD3_k127_8635944_2 protein related to plant photosystem II stability assembly factor - - - 0.000000000000000009725 97.0
HKD3_k127_8635944_3 Protein conserved in bacteria - - - 0.000000000000006192 88.0
HKD3_k127_8635944_4 - - - - 0.0008835 45.0
HKD3_k127_8639574_0 Belongs to the pirin family K06911 - - 0.0000000000003568 70.0
HKD3_k127_8643881_0 Belongs to the peptidase S8 family K20276 - - 0.0000000000000002724 94.0
HKD3_k127_8643881_1 diguanylate cyclase activity - - - 0.0008646 51.0
HKD3_k127_8773126_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 325.0
HKD3_k127_8773126_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001721 275.0
HKD3_k127_8773126_2 PFAM conserved K07027 - - 0.0000000000000000000000000000000000000000006823 171.0
HKD3_k127_8773126_3 membrane - - - 0.000000000000000000000001984 113.0
HKD3_k127_8775376_0 by modhmm K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 314.0
HKD3_k127_8775376_1 NlpC/P60 family - - - 0.000000003013 66.0
HKD3_k127_8794792_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 514.0
HKD3_k127_8794792_1 Oxidoreductase family, C-terminal alpha beta domain K13016 - 1.1.1.335 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 450.0
HKD3_k127_8794792_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 389.0
HKD3_k127_8794792_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 379.0
HKD3_k127_8794792_4 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000005085 231.0
HKD3_k127_8794792_5 Succinoglycan biosynthesis protein exoa - - - 0.00000000000000000000000000000000000003793 156.0
HKD3_k127_8794792_6 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000008731 130.0
HKD3_k127_8811743_0 OPT oligopeptide transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 436.0
HKD3_k127_8811743_1 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000006641 250.0
HKD3_k127_8811743_2 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000007617 198.0
HKD3_k127_8811743_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.00000000000000000000000000000001295 130.0
HKD3_k127_8811743_4 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000005662 77.0
HKD3_k127_8811743_5 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00003995 50.0
HKD3_k127_8838624_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001424 293.0
HKD3_k127_8838624_1 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.0000000000000000000000000000000000000002076 154.0
HKD3_k127_8838624_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000004483 147.0
HKD3_k127_8838624_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000004102 106.0
HKD3_k127_8838624_4 Binds to the 23S rRNA K02896 - - 0.000000000000000000002249 95.0
HKD3_k127_8838624_5 Periplasmic copper-binding protein (NosD) - - - 0.000000000001168 81.0
HKD3_k127_8838624_6 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000001792 68.0
HKD3_k127_8838624_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000526 63.0
HKD3_k127_8838624_8 PFAM PKD domain containing protein K07004 - - 0.0006831 50.0
HKD3_k127_8873178_0 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 513.0
HKD3_k127_8873178_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 486.0
HKD3_k127_8873178_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000004699 167.0
HKD3_k127_8873178_3 archaeal coiled-coil protein - - - 0.0000000000000000000000003974 116.0
HKD3_k127_8873178_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000003352 66.0
HKD3_k127_8873296_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 565.0
HKD3_k127_8873296_1 tRNA binding K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 503.0
HKD3_k127_8873296_2 TIGRFAM RNA modification enzyme, MiaB family K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000005023 256.0
HKD3_k127_8873296_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000004777 207.0
HKD3_k127_8873296_4 but it may be involved in stabilization of the trimeric complex - - - 0.0000009868 53.0
HKD3_k127_8920919_0 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 405.0
HKD3_k127_8920919_1 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000001505 174.0
HKD3_k127_8920919_2 Acyl-protein synthetase, LuxE - - - 0.00000000000000000000000000004759 132.0
HKD3_k127_8920919_3 metal ion transmembrane transporter activity - - - 0.000000000000000000000003141 113.0
HKD3_k127_8920919_4 PFAM conserved K07027 - - 0.0000000003623 71.0
HKD3_k127_8920919_5 Transglutaminase-like superfamily - - - 0.000000002716 68.0
HKD3_k127_8923105_0 COG2041 Sulfite oxidase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 286.0
HKD3_k127_8923105_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000004503 111.0
HKD3_k127_8923105_2 Domain of unknown function (DUF4870) - - - 0.00000000000000000002686 94.0
HKD3_k127_8923105_3 - - - - 0.0000005545 54.0
HKD3_k127_8923105_4 Permeases of the drug metabolite transporter (DMT) superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001954 56.0
HKD3_k127_8945149_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 587.0
HKD3_k127_8945149_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 320.0
HKD3_k127_8945149_2 cell wall organization - - - 0.000000000000000000000112 114.0
HKD3_k127_8945149_3 chromosome segregation and condensation protein ScpA K05896 - - 0.0000007985 54.0
HKD3_k127_8982055_0 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000002274 160.0
HKD3_k127_8982055_1 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000006989 121.0
HKD3_k127_8982055_2 Right handed beta helix region - - - 0.000000000009605 76.0
HKD3_k127_9018708_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1009.0
HKD3_k127_9018708_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2.36e-211 671.0
HKD3_k127_9018708_2 PFAM glycosyl transferase group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 524.0
HKD3_k127_9018708_3 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000008097 226.0
HKD3_k127_9018708_4 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000347 149.0
HKD3_k127_9018708_5 Uncharacterised protein family (UPF0147) K09721 - - 0.000000000000000000000027 101.0
HKD3_k127_9033783_0 Threonine dehydratase K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 347.0
HKD3_k127_9033783_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002365 278.0
HKD3_k127_9033783_2 Domain of unknown function (DUF1805) - - - 0.0000000000000000006304 89.0
HKD3_k127_9033783_3 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.0000000000000001331 94.0
HKD3_k127_908360_0 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000001872 228.0
HKD3_k127_908360_1 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000003381 215.0
HKD3_k127_908360_2 peptidase activity, acting on L-amino acid peptides K01337,K05994,K20276 - 3.4.11.10,3.4.21.50 0.00000000000000000000000000000001242 144.0
HKD3_k127_908360_3 cellular manganese ion homeostasis - - - 0.00000000000000000004086 93.0
HKD3_k127_908360_4 Protein of unknown function (DUF3344) - - - 0.000000000000000001145 102.0
HKD3_k127_908360_5 Flavodoxin K03809 - 1.6.5.2 0.0000002806 58.0
HKD3_k127_9128349_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000001033 196.0
HKD3_k127_9128349_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000009111 160.0
HKD3_k127_9128349_3 Periplasmic copper-binding protein (NosD) - - - 0.000000003774 70.0
HKD3_k127_9269046_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 619.0
HKD3_k127_9269046_1 membrane-associated protein domain - - - 0.000000001301 70.0
HKD3_k127_9269046_2 - - - - 0.0001245 54.0
HKD3_k127_9310517_0 E1-E2 ATPase K01533 - 3.6.3.4 3.688e-288 899.0
HKD3_k127_9310517_1 Short C-terminal domain K08982 - - 0.00000000000000000000000005325 111.0
HKD3_k127_9310517_2 PFAM Peptidase C1A, papain - - - 0.000000006795 67.0
HKD3_k127_9355083_0 COG0058 Glucan phosphorylase - - - 4.109e-222 702.0
HKD3_k127_9355083_1 Glycogen debranching enzyme N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 481.0
HKD3_k127_9355083_2 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 452.0
HKD3_k127_9355083_3 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 430.0
HKD3_k127_9355083_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 373.0
HKD3_k127_9355083_5 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 320.0
HKD3_k127_9355083_6 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 301.0
HKD3_k127_9355083_7 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002027 280.0
HKD3_k127_9355083_8 membrane - - - 0.000000000000000000000000000000000000000001607 167.0
HKD3_k127_9355083_9 AsnC-type helix-turn-helix domain K03718 - - 0.00002173 54.0
HKD3_k127_9374872_0 Lysine exporter protein LysE YggA - - - 0.000000000000000000000000000000000000115 151.0
HKD3_k127_9374872_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000001521 97.0
HKD3_k127_9374872_2 Pkd domain containing protein - - - 0.0000004732 63.0
HKD3_k127_9387954_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 560.0
HKD3_k127_9387954_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000126 198.0
HKD3_k127_9387954_2 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000000000000007224 93.0
HKD3_k127_9387954_3 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.00000000000000003882 83.0
HKD3_k127_9470615_0 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006068 336.0
HKD3_k127_9470615_1 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 311.0
HKD3_k127_9470615_2 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005612 271.0
HKD3_k127_9470615_3 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000103 234.0
HKD3_k127_9470615_4 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000003256 215.0
HKD3_k127_9470615_5 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029 - - 0.0000000000000000000000000000000000000000000000000000000005285 209.0
HKD3_k127_9470615_6 S-acyltransferase activity K00627,K03310,K03578,K12132 - 2.3.1.12,2.7.11.1,3.6.4.13 0.00000000000000000000000000000000000000000000000000000006255 206.0
HKD3_k127_9470615_7 Predicted SAM-dependent RNA methyltransferase - - - 0.000000000000000000000000000000232 131.0
HKD3_k127_9470615_8 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000000009562 121.0
HKD3_k127_9470615_9 Pirin K06911 - - 0.00000000000000000000000000004849 121.0
HKD3_k127_9486223_0 aconitate hydratase K01681 - 4.2.1.3 1.04e-288 899.0
HKD3_k127_9486223_1 TIGRFAM Acetate-CoA ligase K01895 - 6.2.1.1 4.324e-278 868.0
HKD3_k127_9486223_2 ATP-citrate synthase K01648 GO:0000166,GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003878,GO:0005488,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005829,GO:0005886,GO:0006066,GO:0006082,GO:0006084,GO:0006085,GO:0006101,GO:0006107,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006694,GO:0006695,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009893,GO:0009987,GO:0012505,GO:0015936,GO:0016020,GO:0016053,GO:0016125,GO:0016126,GO:0016192,GO:0016740,GO:0016746,GO:0016999,GO:0017076,GO:0017144,GO:0018130,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030141,GO:0030554,GO:0031323,GO:0031325,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032940,GO:0032991,GO:0033500,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0034774,GO:0035337,GO:0035383,GO:0035384,GO:0035578,GO:0035639,GO:0036094,GO:0036230,GO:0042119,GO:0042582,GO:0042592,GO:0042593,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046165,GO:0046390,GO:0046394,GO:0046483,GO:0046903,GO:0046912,GO:0046949,GO:0048518,GO:0048522,GO:0048878,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0055086,GO:0060205,GO:0065007,GO:0065008,GO:0070013,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:0101002,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901568,GO:1901570,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653,GO:1904813 2.3.3.8 1.27e-252 794.0
HKD3_k127_9486223_3 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 566.0
HKD3_k127_9486223_4 ATP citrate synthase activity K01648 GO:0003674,GO:0003824,GO:0003878,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006084,GO:0006085,GO:0006091,GO:0006101,GO:0006139,GO:0006163,GO:0006164,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009346,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016999,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046394,GO:0046483,GO:0046912,GO:0051186,GO:0051188,GO:0055086,GO:0071616,GO:0071704,GO:0071944,GO:0072330,GO:0072350,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 545.0
HKD3_k127_9486223_5 Fumarate hydratase K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005644 317.0
HKD3_k127_9486223_6 COG1522 Transcriptional regulators - - - 0.00000000000000000000005383 111.0
HKD3_k127_9486223_7 Fumarase C-terminus K01678 - 4.2.1.2 0.0000000000002225 74.0
HKD3_k127_9564327_0 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000001591 171.0
HKD3_k127_9564327_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000001032 158.0
HKD3_k127_9625461_0 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 316.0
HKD3_k127_9625461_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 304.0
HKD3_k127_9625461_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000148 304.0
HKD3_k127_9625461_3 Major Facilitator Superfamily - - - 0.00000008488 60.0
HKD3_k127_9652092_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 1.497e-196 623.0
HKD3_k127_9652092_1 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000141 220.0
HKD3_k127_9652092_2 PFAM phosphoadenosine phosphosulfate reductase K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000011 206.0
HKD3_k127_9652092_3 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000001083 193.0
HKD3_k127_9652092_4 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000001716 177.0
HKD3_k127_9652092_5 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000004123 170.0
HKD3_k127_9652092_6 deoxyribonucleoside 5'-monophosphate N-glycosidase activity K09457 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 1.7.1.13 0.00001449 54.0