Overview

ID MAG01870
Name HKD3_bin.66
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Desulfobaccia
Order Desulfobaccales
Family 0-14-0-80-60-11
Genus 0-14-0-80-60-11
Species
Assembly information
Completeness (%) 85.79
Contamination (%) 1.01
GC content (%) 61.0
N50 (bp) 25,984
Genome size (bp) 2,668,293

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2372

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1208089_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1233.0
HKD3_k127_1208089_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.886e-224 701.0
HKD3_k127_1208089_11 Gram-negative-bacterium-type cell outer membrane assembly K21572 - - 0.000000000000000000000000001232 116.0
HKD3_k127_1208089_2 PFAM Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 1.403e-205 648.0
HKD3_k127_1208089_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 449.0
HKD3_k127_1208089_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 374.0
HKD3_k127_1208089_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 339.0
HKD3_k127_1208089_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007486 267.0
HKD3_k127_1208089_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000001691 183.0
HKD3_k127_1208089_8 PFAM zinc finger, DksA TraR C4-type K06204 - - 0.00000000000000000000000000000000000000000000006382 171.0
HKD3_k127_1225195_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1169.0
HKD3_k127_1225195_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 1.967e-281 878.0
HKD3_k127_1225195_11 GlcNAc transferase - - - 0.000000000009191 72.0
HKD3_k127_1225195_12 Transposase is116 is110 is902 family K07486 - - 0.000001582 49.0
HKD3_k127_1225195_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 620.0
HKD3_k127_1225195_3 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 467.0
HKD3_k127_1225195_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 425.0
HKD3_k127_1225195_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 380.0
HKD3_k127_1225195_6 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 296.0
HKD3_k127_1225195_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000002864 183.0
HKD3_k127_1225195_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000003804 186.0
HKD3_k127_1225195_9 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000004402 124.0
HKD3_k127_1228234_0 Efflux pump membrane transporter K03296 - - 0.0 1197.0
HKD3_k127_1228234_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 314.0
HKD3_k127_125885_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1031.0
HKD3_k127_125885_1 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 478.0
HKD3_k127_125885_2 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 404.0
HKD3_k127_128528_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001476 289.0
HKD3_k127_128528_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000005755 237.0
HKD3_k127_128528_2 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000001685 192.0
HKD3_k127_128528_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000444 151.0
HKD3_k127_128528_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000004542 138.0
HKD3_k127_128528_5 Belongs to the UPF0109 family K06960 - - 0.0000000000000000001575 89.0
HKD3_k127_1422342_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1336.0
HKD3_k127_1422342_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.476e-283 890.0
HKD3_k127_1422342_10 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 419.0
HKD3_k127_1422342_11 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 413.0
HKD3_k127_1422342_12 PFAM ABC transporter K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 402.0
HKD3_k127_1422342_13 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 397.0
HKD3_k127_1422342_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 392.0
HKD3_k127_1422342_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 364.0
HKD3_k127_1422342_16 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 357.0
HKD3_k127_1422342_17 curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 347.0
HKD3_k127_1422342_18 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 344.0
HKD3_k127_1422342_19 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 335.0
HKD3_k127_1422342_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 6.526e-237 746.0
HKD3_k127_1422342_20 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000468 334.0
HKD3_k127_1422342_21 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003744 312.0
HKD3_k127_1422342_22 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001147 280.0
HKD3_k127_1422342_23 Carotenoid biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000983 280.0
HKD3_k127_1422342_24 Prephenate dehydrogenase K04517,K14187 - 1.3.1.12,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001334 270.0
HKD3_k127_1422342_25 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006491 262.0
HKD3_k127_1422342_26 Phosphorylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006472 258.0
HKD3_k127_1422342_27 PFAM Uncharacterised protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002382 240.0
HKD3_k127_1422342_28 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000002607 233.0
HKD3_k127_1422342_29 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001894 209.0
HKD3_k127_1422342_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.56e-197 627.0
HKD3_k127_1422342_30 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000002126 175.0
HKD3_k127_1422342_31 PFAM response regulator receiveR - - - 0.00000000000000000000000000000000000000003611 158.0
HKD3_k127_1422342_32 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000005346 155.0
HKD3_k127_1422342_33 PAS domain - - - 0.00000000000000000000000000000000003503 152.0
HKD3_k127_1422342_34 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000006117 137.0
HKD3_k127_1422342_35 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000262 124.0
HKD3_k127_1422342_36 S23 ribosomal protein - - - 0.00000000000000000000000000009257 120.0
HKD3_k127_1422342_37 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000007769 114.0
HKD3_k127_1422342_38 TIGRFAM Competence protein ComEA, helix-hairpin-helix K02237 - - 0.0000000000000000001618 95.0
HKD3_k127_1422342_39 PFAM purine or other phosphorylase family 1 K01243 - 3.2.2.9 0.000000000000000008336 93.0
HKD3_k127_1422342_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 9.282e-197 623.0
HKD3_k127_1422342_40 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000001217 84.0
HKD3_k127_1422342_5 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 516.0
HKD3_k127_1422342_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 505.0
HKD3_k127_1422342_7 Cytochrome c5530 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 476.0
HKD3_k127_1422342_8 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 443.0
HKD3_k127_1422342_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 432.0
HKD3_k127_1431371_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1137.0
HKD3_k127_1431371_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 520.0
HKD3_k127_1431371_10 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000000002626 201.0
HKD3_k127_1431371_11 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000000000004233 196.0
HKD3_k127_1431371_12 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000002412 195.0
HKD3_k127_1431371_13 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000000000000000000000000000000004732 170.0
HKD3_k127_1431371_14 Highly conserved protein containing a thioredoxin domain - - - 0.0000000000000000000000000000000000001315 145.0
HKD3_k127_1431371_15 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000000547 128.0
HKD3_k127_1431371_16 unfolded protein binding K06142 - - 0.000000000000000000000000002174 117.0
HKD3_k127_1431371_18 TadE-like protein - - - 0.0001415 48.0
HKD3_k127_1431371_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 417.0
HKD3_k127_1431371_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 389.0
HKD3_k127_1431371_4 PFAM Glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 362.0
HKD3_k127_1431371_5 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 344.0
HKD3_k127_1431371_6 Beta-lactamase enzyme family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007923 321.0
HKD3_k127_1431371_7 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 291.0
HKD3_k127_1431371_8 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006195 280.0
HKD3_k127_1431371_9 - - - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
HKD3_k127_1449307_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1142.0
HKD3_k127_1449307_1 Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP- dependent clade X sub-subfamily K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 537.0
HKD3_k127_1449307_2 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 404.0
HKD3_k127_1449307_3 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000003312 121.0
HKD3_k127_1449307_4 transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000000002401 73.0
HKD3_k127_14874_0 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 2.871e-211 662.0
HKD3_k127_14874_1 Orotidine 5'-phosphate decarboxylase / HUMPS family K13831 - 4.1.2.43,5.3.1.27 6.67e-201 633.0
HKD3_k127_14874_2 COGs COG0794 sugar phosphate isomerase involved in capsule formation K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000001235 193.0
HKD3_k127_14874_3 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000000002828 141.0
HKD3_k127_14874_4 PFAM ROSMUCR transcriptional regulator - - - 0.00001102 51.0
HKD3_k127_1489150_0 PFAM 4Fe-4S binding domain - - - 8.105e-218 686.0
HKD3_k127_1489150_1 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008049 548.0
HKD3_k127_1489150_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 469.0
HKD3_k127_1489150_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009133 444.0
HKD3_k127_1489150_4 Di-haem oxidoreductase, putative peroxidase K01201 - 3.2.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 281.0
HKD3_k127_1489150_5 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002338 265.0
HKD3_k127_1489150_6 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000002333 81.0
HKD3_k127_1489150_7 transposition, DNA-mediated - - - 0.000002602 49.0
HKD3_k127_153944_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 9.274e-318 993.0
HKD3_k127_153944_1 Histidine kinase K07709 - 2.7.13.3 1.322e-258 818.0
HKD3_k127_153944_2 Elongation factor Tu domain 2 K03833 - - 1.465e-252 793.0
HKD3_k127_153944_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.405e-203 643.0
HKD3_k127_153944_4 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 547.0
HKD3_k127_153944_5 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 472.0
HKD3_k127_153944_6 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 291.0
HKD3_k127_153944_7 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000008772 190.0
HKD3_k127_153944_8 Protein of unknown function (DUF2905) - - - 0.00000000000000000006234 90.0
HKD3_k127_1575699_0 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 3.668e-293 919.0
HKD3_k127_1575699_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 8.233e-284 879.0
HKD3_k127_1575699_10 helix_turn_helix, mercury resistance - - - 0.0000000000000004927 84.0
HKD3_k127_1575699_2 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008282 580.0
HKD3_k127_1575699_3 Chromate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 456.0
HKD3_k127_1575699_4 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 435.0
HKD3_k127_1575699_5 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 312.0
HKD3_k127_1575699_6 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.00000000000000000000000000000000000000000000004019 178.0
HKD3_k127_1575699_7 PFAM ROSMUCR transcriptional regulator - - - 0.00000000000000000000000000000000000000008299 155.0
HKD3_k127_1575699_8 Right handed beta helix region - - - 0.000000000000000000000000000001381 131.0
HKD3_k127_1575699_9 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000008768 118.0
HKD3_k127_1629555_0 COG0058 Glucan phosphorylase K00688 - 2.4.1.1 2.639e-303 944.0
HKD3_k127_1629555_1 Conserved hypothetical protein 698 - - - 1.507e-248 774.0
HKD3_k127_1629555_10 Flavodoxin-like fold K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 284.0
HKD3_k127_1629555_11 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008682 280.0
HKD3_k127_1629555_12 PFAM Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001922 279.0
HKD3_k127_1629555_13 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
HKD3_k127_1629555_14 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000006103 219.0
HKD3_k127_1629555_15 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000000004975 210.0
HKD3_k127_1629555_16 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000001488 186.0
HKD3_k127_1629555_17 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000000000000000000000000000002609 152.0
HKD3_k127_1629555_19 - - - - 0.00000000000000000000004654 99.0
HKD3_k127_1629555_2 Conserved hypothetical protein 698 - - - 2.418e-221 699.0
HKD3_k127_1629555_20 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000002328 98.0
HKD3_k127_1629555_21 Uncharacterised ArCR, COG2043 - - - 0.000000000000000001081 95.0
HKD3_k127_1629555_22 PFAM Protein-tyrosine phosphatase, low molecular weight K03741 - 1.20.4.1 0.00000000000000005235 86.0
HKD3_k127_1629555_23 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000001059 64.0
HKD3_k127_1629555_3 PFAM isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 562.0
HKD3_k127_1629555_4 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004401 565.0
HKD3_k127_1629555_5 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 518.0
HKD3_k127_1629555_6 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 493.0
HKD3_k127_1629555_7 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 369.0
HKD3_k127_1629555_8 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 332.0
HKD3_k127_1629555_9 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 325.0
HKD3_k127_1734093_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2073.0
HKD3_k127_1734093_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1162.0
HKD3_k127_1734093_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 367.0
HKD3_k127_1734093_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006091 278.0
HKD3_k127_1734093_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000696 264.0
HKD3_k127_1734093_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003955 213.0
HKD3_k127_1734093_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000002991 166.0
HKD3_k127_1734093_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000321 145.0
HKD3_k127_1734093_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000209 87.0
HKD3_k127_1734093_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000004 84.0
HKD3_k127_1803921_0 Type II and III secretion system protein K02453 - - 4.675e-259 822.0
HKD3_k127_1803921_1 PFAM Type II secretion system protein E K02454 - - 4.098e-245 765.0
HKD3_k127_1803921_10 PFAM Fimbrial assembly K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 426.0
HKD3_k127_1803921_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 414.0
HKD3_k127_1803921_12 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 403.0
HKD3_k127_1803921_13 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 397.0
HKD3_k127_1803921_14 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 349.0
HKD3_k127_1803921_15 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 332.0
HKD3_k127_1803921_16 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 293.0
HKD3_k127_1803921_17 PFAM General secretion pathway protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 289.0
HKD3_k127_1803921_18 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002953 271.0
HKD3_k127_1803921_19 Conserved TM helix K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005253 251.0
HKD3_k127_1803921_2 Amino acid permease - - - 2.996e-237 748.0
HKD3_k127_1803921_20 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000909 237.0
HKD3_k127_1803921_21 PFAM type II secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000000007873 216.0
HKD3_k127_1803921_22 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000006271 189.0
HKD3_k127_1803921_23 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000008599 188.0
HKD3_k127_1803921_24 cytochrome c nitrate reductase, small subunit K15876 - - 0.000000000000000000000000000000000000000000000000001085 186.0
HKD3_k127_1803921_25 protein transport across the cell outer membrane K02457,K08084 - - 0.000000000000000000000000000000000000167 147.0
HKD3_k127_1803921_27 Late embryogenesis abundant protein - - - 0.0000000000000000000000000000000007638 139.0
HKD3_k127_1803921_28 type IV pilus modification protein PilV K02458,K02671,K02681 - - 0.00000000000000000000000000008147 124.0
HKD3_k127_1803921_3 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 1.644e-207 667.0
HKD3_k127_1803921_30 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000004255 105.0
HKD3_k127_1803921_32 - - - - 0.0000000000000003729 85.0
HKD3_k127_1803921_4 TIGRFAM Ammonium transporter K03320 - - 8.616e-207 657.0
HKD3_k127_1803921_5 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.225e-198 629.0
HKD3_k127_1803921_6 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 578.0
HKD3_k127_1803921_7 General secretion pathway protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 548.0
HKD3_k127_1803921_8 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 527.0
HKD3_k127_1803921_9 COGs COG0399 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 447.0
HKD3_k127_1840500_0 Pyruvate:ferredoxin oxidoreductase core domain II K03737 - 1.2.7.1 0.0 2070.0
HKD3_k127_1840500_1 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0 1077.0
HKD3_k127_1840500_10 OsmC-like protein - - - 0.000000005123 65.0
HKD3_k127_1840500_2 4Fe-4S binding domain - - - 8.066e-243 762.0
HKD3_k127_1840500_3 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 518.0
HKD3_k127_1840500_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 488.0
HKD3_k127_1840500_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 434.0
HKD3_k127_1840500_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002566 267.0
HKD3_k127_1840500_7 - - - - 0.0000000000000000000000000000000000000000000000000001241 194.0
HKD3_k127_1840500_8 Nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000001133 184.0
HKD3_k127_1864487_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1449.0
HKD3_k127_1864487_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.0 1157.0
HKD3_k127_1864487_10 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000004509 205.0
HKD3_k127_1864487_11 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000001333 196.0
HKD3_k127_1864487_12 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000005179 210.0
HKD3_k127_1864487_13 Hydrogenase maturation protease K00442 - - 0.0000000000000000000000000000000000000000000000000001035 190.0
HKD3_k127_1864487_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000001314 192.0
HKD3_k127_1864487_15 PFAM Cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000009673 167.0
HKD3_k127_1864487_16 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000006896 131.0
HKD3_k127_1864487_17 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000006436 130.0
HKD3_k127_1864487_18 nickel cation binding K04651 - - 0.00000000000000000000000001956 113.0
HKD3_k127_1864487_19 FAD dependent oxidoreductase - - - 0.0000000000000000000000001509 107.0
HKD3_k127_1864487_2 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 624.0
HKD3_k127_1864487_20 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000001576 98.0
HKD3_k127_1864487_21 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000001799 85.0
HKD3_k127_1864487_23 ISXO2-like transposase domain - - - 0.000000000001364 68.0
HKD3_k127_1864487_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 522.0
HKD3_k127_1864487_4 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 453.0
HKD3_k127_1864487_5 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 408.0
HKD3_k127_1864487_6 PFAM NADH ubiquinone K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 404.0
HKD3_k127_1864487_7 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 393.0
HKD3_k127_1864487_8 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 390.0
HKD3_k127_1864487_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000001399 226.0
HKD3_k127_1936708_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 3.935e-313 982.0
HKD3_k127_1936708_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 2.823e-293 911.0
HKD3_k127_1936708_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 1.016e-196 619.0
HKD3_k127_1936708_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 542.0
HKD3_k127_1936708_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001659 204.0
HKD3_k127_1936708_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000004487 195.0
HKD3_k127_1936708_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000001837 171.0
HKD3_k127_1936708_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000000000001452 162.0
HKD3_k127_1936708_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000003267 96.0
HKD3_k127_1937494_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 505.0
HKD3_k127_1937494_1 Coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 506.0
HKD3_k127_1937494_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 409.0
HKD3_k127_1937494_3 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005316 354.0
HKD3_k127_1937494_4 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 319.0
HKD3_k127_1937494_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000009014 220.0
HKD3_k127_1937494_6 Domain of unknown function (DUF3842) - - - 0.0000000000000000000000000000000000000000000000000000000000003138 213.0
HKD3_k127_1937494_7 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000001342 161.0
HKD3_k127_1975814_0 tryptophan synthase activity K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006279 485.0
HKD3_k127_1975814_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000003842 269.0
HKD3_k127_1975814_2 TPR Domain containing protein K12600 - - 0.000000000000000001455 94.0
HKD3_k127_1975814_3 - - - - 0.000000512 61.0
HKD3_k127_1975814_4 PQQ-like domain K00117 - 1.1.5.2 0.00002144 51.0
HKD3_k127_1975814_6 SMART Tetratricopeptide - - - 0.00008125 51.0
HKD3_k127_2068725_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 531.0
HKD3_k127_2068725_1 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 507.0
HKD3_k127_2068725_10 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007612 257.0
HKD3_k127_2068725_11 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000551 242.0
HKD3_k127_2068725_12 PFAM Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000001595 236.0
HKD3_k127_2068725_13 PFAM glycosyl transferase family 9 - - - 0.000000000000000000000000000000000000000000000000000000000000000002941 240.0
HKD3_k127_2068725_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000001608 220.0
HKD3_k127_2068725_15 Mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000007625 217.0
HKD3_k127_2068725_16 SAF K02279 - - 0.00000000000000000000000000000000000000000000000000000000009565 213.0
HKD3_k127_2068725_17 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000007645 184.0
HKD3_k127_2068725_18 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000004513 166.0
HKD3_k127_2068725_19 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000001796 147.0
HKD3_k127_2068725_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 490.0
HKD3_k127_2068725_21 RelB antitoxin K07473 - - 0.00000000000000000000002136 103.0
HKD3_k127_2068725_22 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 - - 0.00000000000000000000002394 105.0
HKD3_k127_2068725_23 - - - - 0.00000000000000000000008835 100.0
HKD3_k127_2068725_24 - - - - 0.00000000000000008707 82.0
HKD3_k127_2068725_25 TadE-like protein - - - 0.0000000007539 64.0
HKD3_k127_2068725_26 Flp/Fap pilin component K02651 - - 0.00000001766 57.0
HKD3_k127_2068725_3 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006466 466.0
HKD3_k127_2068725_4 PFAM Type II secretion system protein E K02283,K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 448.0
HKD3_k127_2068725_5 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 380.0
HKD3_k127_2068725_6 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003121 341.0
HKD3_k127_2068725_7 PFAM Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 310.0
HKD3_k127_2068725_8 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 293.0
HKD3_k127_2068725_9 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 283.0
HKD3_k127_2116123_0 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 1.833e-233 735.0
HKD3_k127_2116123_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 466.0
HKD3_k127_2116123_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000001185 194.0
HKD3_k127_2140304_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 585.0
HKD3_k127_2140304_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 520.0
HKD3_k127_2140304_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 506.0
HKD3_k127_2140304_3 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 475.0
HKD3_k127_2140304_4 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 432.0
HKD3_k127_2140304_5 amino acid activation for nonribosomal peptide biosynthetic process K20952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 296.0
HKD3_k127_2140304_6 QueT transporter K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000176 242.0
HKD3_k127_2250189_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.452e-276 851.0
HKD3_k127_2250189_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 411.0
HKD3_k127_2250189_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001255 277.0
HKD3_k127_2250189_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000001617 188.0
HKD3_k127_230278_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1738.0
HKD3_k127_230278_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1387.0
HKD3_k127_230278_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 506.0
HKD3_k127_230278_11 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 474.0
HKD3_k127_230278_12 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 460.0
HKD3_k127_230278_13 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 466.0
HKD3_k127_230278_14 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009652 419.0
HKD3_k127_230278_15 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 392.0
HKD3_k127_230278_16 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 340.0
HKD3_k127_230278_17 domain protein K01992,K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 303.0
HKD3_k127_230278_18 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
HKD3_k127_230278_19 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 292.0
HKD3_k127_230278_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 1.898e-262 834.0
HKD3_k127_230278_20 acetyltransferase K00661 - 2.3.1.79 0.000000000000000000000000000000000000000000000000000000009793 203.0
HKD3_k127_230278_21 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000001165 173.0
HKD3_k127_230278_22 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000000000000005289 161.0
HKD3_k127_230278_23 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000002034 156.0
HKD3_k127_230278_24 membrane K00389 - - 0.00000000000000000000000000000000003138 146.0
HKD3_k127_230278_25 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000002174 136.0
HKD3_k127_230278_26 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000368 129.0
HKD3_k127_230278_27 Sec-independent protein translocase protein TatA K03116 - - 0.000000000000000000000000000002939 122.0
HKD3_k127_230278_28 Putative Tad-like Flp pilus-assembly - - - 0.00000000000000000000000000001131 131.0
HKD3_k127_230278_29 Putative Tad-like Flp pilus-assembly - - - 0.00000000000000000000000000004724 129.0
HKD3_k127_230278_3 Fe-S oxidoreductase - - - 4.921e-199 640.0
HKD3_k127_230278_30 Sec-independent protein translocase protein TatA K03116,K03117,K03646 - - 0.0000000000000003441 82.0
HKD3_k127_230278_32 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000004408 51.0
HKD3_k127_230278_4 - K03293 - - 1.876e-196 620.0
HKD3_k127_230278_5 CoA-transferase family III K01796 - 5.1.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 571.0
HKD3_k127_230278_6 PFAM MgsA AAA ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 552.0
HKD3_k127_230278_7 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 529.0
HKD3_k127_230278_8 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 520.0
HKD3_k127_230278_9 PFAM Acyl-CoA dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 518.0
HKD3_k127_2339104_0 AAA domain (dynein-related subfamily) K03404,K03405 - 6.6.1.1 3.512e-200 642.0
HKD3_k127_2339104_1 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 598.0
HKD3_k127_2339104_10 - - - - 0.00000000005378 67.0
HKD3_k127_2339104_11 Uncharacterized protein conserved in bacteria (DUF2059) K09924 - - 0.0002252 51.0
HKD3_k127_2339104_12 LytR cell envelope-related transcriptional attenuator - - - 0.0003011 52.0
HKD3_k127_2339104_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 577.0
HKD3_k127_2339104_3 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001589 237.0
HKD3_k127_2339104_4 Phosphoesterase K07095 - - 0.00000000000000000000000000000000000000000000000000007256 190.0
HKD3_k127_2339104_5 cytolysis by virus of host cell K01185 - 3.2.1.17 0.0000000000000000000000000000000000000000000537 168.0
HKD3_k127_2339104_6 COGs COG0741 Soluble lytic murein transglycosylase and related regulatory protein (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000000001297 167.0
HKD3_k127_2339104_7 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000005294 113.0
HKD3_k127_2339104_8 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000001051 96.0
HKD3_k127_2435195_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0 1143.0
HKD3_k127_2435195_1 E1-E2 ATPase K01547 - 3.6.3.12 6.265e-308 962.0
HKD3_k127_2435195_10 carbon starvation protein CstA K06200 - - 9.091e-194 619.0
HKD3_k127_2435195_11 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 592.0
HKD3_k127_2435195_12 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 493.0
HKD3_k127_2435195_13 transport system involved in gliding motility auxiliary component-like K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 474.0
HKD3_k127_2435195_14 PBP superfamily domain K02040 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0006950,GO:0006974,GO:0008150,GO:0009314,GO:0009628,GO:0009987,GO:0010921,GO:0015698,GO:0019220,GO:0019222,GO:0030288,GO:0030313,GO:0031323,GO:0031975,GO:0033554,GO:0035303,GO:0042301,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051174,GO:0051179,GO:0051234,GO:0051336,GO:0051716,GO:0065007,GO:0065009 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 467.0
HKD3_k127_2435195_15 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 460.0
HKD3_k127_2435195_16 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 449.0
HKD3_k127_2435195_17 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 430.0
HKD3_k127_2435195_18 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 432.0
HKD3_k127_2435195_19 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 416.0
HKD3_k127_2435195_2 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 5.809e-301 940.0
HKD3_k127_2435195_20 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 409.0
HKD3_k127_2435195_21 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 414.0
HKD3_k127_2435195_22 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 399.0
HKD3_k127_2435195_23 Polysaccharide biosynthesis protein K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 391.0
HKD3_k127_2435195_24 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 356.0
HKD3_k127_2435195_25 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 356.0
HKD3_k127_2435195_26 PFAM response regulator receiver K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 329.0
HKD3_k127_2435195_27 PFAM Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 336.0
HKD3_k127_2435195_28 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 323.0
HKD3_k127_2435195_29 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 321.0
HKD3_k127_2435195_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 6.154e-271 847.0
HKD3_k127_2435195_30 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 306.0
HKD3_k127_2435195_31 PFAM short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009865 298.0
HKD3_k127_2435195_32 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006328 298.0
HKD3_k127_2435195_33 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003987 294.0
HKD3_k127_2435195_34 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005235 270.0
HKD3_k127_2435195_35 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001228 264.0
HKD3_k127_2435195_36 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003867 264.0
HKD3_k127_2435195_37 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000002162 258.0
HKD3_k127_2435195_38 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004331 260.0
HKD3_k127_2435195_39 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000001777 257.0
HKD3_k127_2435195_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 1.389e-263 824.0
HKD3_k127_2435195_40 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007959 263.0
HKD3_k127_2435195_41 Phosphorylase superfamily K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000006464 223.0
HKD3_k127_2435195_42 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000004019 207.0
HKD3_k127_2435195_43 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000001598 177.0
HKD3_k127_2435195_44 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000008036 175.0
HKD3_k127_2435195_45 - - - - 0.00000000000000000000000000000000000000001518 154.0
HKD3_k127_2435195_46 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000001034 139.0
HKD3_k127_2435195_47 ribonuclease activity - - - 0.0000000000000000000000000003962 117.0
HKD3_k127_2435195_48 Protein of unknown function DUF116 - - - 0.000000000000004663 85.0
HKD3_k127_2435195_5 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 9.286e-260 805.0
HKD3_k127_2435195_51 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000009902 70.0
HKD3_k127_2435195_52 - - - - 0.00002144 51.0
HKD3_k127_2435195_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K11383 - 2.7.13.3 4.139e-242 762.0
HKD3_k127_2435195_7 PFAM response regulator receiver K11384 - - 7.206e-215 675.0
HKD3_k127_2435195_8 Signal transduction histidine kinase K07636 - 2.7.13.3 2.873e-198 633.0
HKD3_k127_2435195_9 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 9.194e-196 615.0
HKD3_k127_2447769_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.485e-303 942.0
HKD3_k127_2447769_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 406.0
HKD3_k127_2447769_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 320.0
HKD3_k127_2447769_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000288 233.0
HKD3_k127_2447769_4 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000000000001432 129.0
HKD3_k127_2447769_5 Bacterial PH domain - - - 0.000000000000000000000003662 107.0
HKD3_k127_2447769_6 PFAM response regulator receiver - - - 0.0000000000000006238 77.0
HKD3_k127_2447769_7 Yip1 domain - - - 0.00000000004453 72.0
HKD3_k127_2448760_0 PFAM Major Facilitator Superfamily K08177 - - 2.847e-215 674.0
HKD3_k127_2448760_1 two component, sigma54 specific, transcriptional regulator, Fis family - - - 4.054e-204 644.0
HKD3_k127_2448760_10 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000207 196.0
HKD3_k127_2448760_11 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000002802 188.0
HKD3_k127_2448760_12 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000002336 134.0
HKD3_k127_2448760_15 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.00000000000000009576 83.0
HKD3_k127_2448760_16 SPTR CopG domain protein DNA-binding domain protein - - - 0.000000000002279 72.0
HKD3_k127_2448760_17 Protein of unknown function (DUF3096) - - - 0.000000006154 58.0
HKD3_k127_2448760_2 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 8.538e-195 617.0
HKD3_k127_2448760_3 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 565.0
HKD3_k127_2448760_4 VWA containing CoxE family protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 485.0
HKD3_k127_2448760_5 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 481.0
HKD3_k127_2448760_6 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 432.0
HKD3_k127_2448760_7 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000002359 271.0
HKD3_k127_2448760_8 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000002542 211.0
HKD3_k127_2448760_9 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000000000000000000000000005406 202.0
HKD3_k127_2461527_0 molybdopterin cofactor binding K08352 - 1.8.5.5 7.709e-284 890.0
HKD3_k127_2461527_1 Belongs to the TPP enzyme family K04103 - 4.1.1.74 2.881e-241 758.0
HKD3_k127_2461527_10 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 478.0
HKD3_k127_2461527_11 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 426.0
HKD3_k127_2461527_12 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 397.0
HKD3_k127_2461527_13 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 391.0
HKD3_k127_2461527_14 Restriction endonuclease K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 389.0
HKD3_k127_2461527_15 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 372.0
HKD3_k127_2461527_16 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 374.0
HKD3_k127_2461527_17 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 362.0
HKD3_k127_2461527_18 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 348.0
HKD3_k127_2461527_19 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 331.0
HKD3_k127_2461527_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 2.841e-212 668.0
HKD3_k127_2461527_20 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 346.0
HKD3_k127_2461527_21 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 334.0
HKD3_k127_2461527_22 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 320.0
HKD3_k127_2461527_23 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 324.0
HKD3_k127_2461527_24 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 319.0
HKD3_k127_2461527_25 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 330.0
HKD3_k127_2461527_26 Restriction endonuclease K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 310.0
HKD3_k127_2461527_27 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 314.0
HKD3_k127_2461527_28 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
HKD3_k127_2461527_29 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 311.0
HKD3_k127_2461527_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 1.253e-195 619.0
HKD3_k127_2461527_30 PFAM import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 293.0
HKD3_k127_2461527_31 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001247 291.0
HKD3_k127_2461527_32 4 iron, 4 sulfur cluster binding K04014,K08353,K08358,K16293 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0030288,GO:0030313,GO:0031975,GO:0042279,GO:0042597,GO:0044464,GO:0055114,GO:0098809 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008755 278.0
HKD3_k127_2461527_33 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001258 275.0
HKD3_k127_2461527_34 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000002282 269.0
HKD3_k127_2461527_35 Product type r regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 266.0
HKD3_k127_2461527_36 Polysulfide reductase K16294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004172 271.0
HKD3_k127_2461527_37 protein histidine kinase activity K07315,K07641,K10819,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003656 282.0
HKD3_k127_2461527_38 lipoprotein transporter activity K02003,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000142 253.0
HKD3_k127_2461527_39 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003531 252.0
HKD3_k127_2461527_4 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 566.0
HKD3_k127_2461527_40 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000004346 253.0
HKD3_k127_2461527_41 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000001107 253.0
HKD3_k127_2461527_42 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
HKD3_k127_2461527_43 Nudix N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000001449 230.0
HKD3_k127_2461527_44 PFAM Cytochrome b b6 domain - - - 0.00000000000000000000000000000000000000000000000000000000000001308 221.0
HKD3_k127_2461527_46 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000002821 230.0
HKD3_k127_2461527_47 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000002417 199.0
HKD3_k127_2461527_48 B12 binding domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000005006 196.0
HKD3_k127_2461527_49 response regulator, receiver K02485 - - 0.0000000000000000000000000000000000000000000000000003846 187.0
HKD3_k127_2461527_5 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 537.0
HKD3_k127_2461527_50 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000002104 189.0
HKD3_k127_2461527_52 Staphylococcal nuclease homologues - - - 0.00000000000000000000000000000000000000000003336 169.0
HKD3_k127_2461527_53 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000008336 168.0
HKD3_k127_2461527_54 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.00000000000000000000000000000000000000212 151.0
HKD3_k127_2461527_55 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000002201 130.0
HKD3_k127_2461527_56 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000000000000000000002533 136.0
HKD3_k127_2461527_57 - - - - 0.000000000000000000000000000005797 121.0
HKD3_k127_2461527_58 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000003545 114.0
HKD3_k127_2461527_59 AAA domain K07028 - - 0.000000000000000000000005395 109.0
HKD3_k127_2461527_6 cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 539.0
HKD3_k127_2461527_60 Belongs to the peptidase M50B family - - - 0.000000000000000000000008704 114.0
HKD3_k127_2461527_61 oxidoreductase activity, acting on diphenols and related substances as donors K02636 - 1.10.9.1 0.0000000000000000000001199 105.0
HKD3_k127_2461527_62 - - - - 0.0000000000000003216 82.0
HKD3_k127_2461527_63 - - - - 0.000000000000003568 84.0
HKD3_k127_2461527_64 Rhodanese Homology Domain - - - 0.00000002091 64.0
HKD3_k127_2461527_66 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.00003259 46.0
HKD3_k127_2461527_7 Male sterility protein K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 495.0
HKD3_k127_2461527_8 TIGRFAM Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 487.0
HKD3_k127_2461527_9 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 480.0
HKD3_k127_2515541_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1191.0
HKD3_k127_2515541_1 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 9.78e-277 865.0
HKD3_k127_2515541_10 PFAM CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 473.0
HKD3_k127_2515541_11 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 440.0
HKD3_k127_2515541_12 PFAM CBS domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 418.0
HKD3_k127_2515541_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 371.0
HKD3_k127_2515541_14 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 347.0
HKD3_k127_2515541_15 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 312.0
HKD3_k127_2515541_16 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 293.0
HKD3_k127_2515541_17 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 292.0
HKD3_k127_2515541_18 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 295.0
HKD3_k127_2515541_19 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000001824 222.0
HKD3_k127_2515541_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 7.382e-273 847.0
HKD3_k127_2515541_20 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000003161 205.0
HKD3_k127_2515541_21 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000114 191.0
HKD3_k127_2515541_23 Rhomboid family K07059 - - 0.00000000000000000000000000000000000000001799 161.0
HKD3_k127_2515541_24 PAS fold - - - 0.0000000000000000000000000000000000000001125 162.0
HKD3_k127_2515541_25 cellulose binding - - - 0.000000000000000000000000000000000000000198 171.0
HKD3_k127_2515541_26 PFAM regulatory protein, ArsR K22043 - - 0.00000000000000000000000000000000001363 138.0
HKD3_k127_2515541_27 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001289 139.0
HKD3_k127_2515541_29 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000001471 113.0
HKD3_k127_2515541_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 612.0
HKD3_k127_2515541_30 Beta-lactamase K01286 - 3.4.16.4 0.0000000000000000000000279 116.0
HKD3_k127_2515541_31 Sh3 type 3 domain protein K03642,K07184 - - 0.000000000000000000005043 99.0
HKD3_k127_2515541_33 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000003462 70.0
HKD3_k127_2515541_34 - - - - 0.000004404 50.0
HKD3_k127_2515541_35 - - - - 0.0002596 52.0
HKD3_k127_2515541_4 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000898 592.0
HKD3_k127_2515541_5 PFAM Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 509.0
HKD3_k127_2515541_6 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007445 501.0
HKD3_k127_2515541_7 PFAM Glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 489.0
HKD3_k127_2515541_8 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 473.0
HKD3_k127_2515541_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 467.0
HKD3_k127_2519426_0 PFAM pyruvate phosphate dikinase, PEP pyruvate-binding K01007 - 2.7.9.2 0.0 1135.0
HKD3_k127_2519426_1 Cytochrome c554 and c-prime - - - 2.84e-295 927.0
HKD3_k127_2519426_10 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 409.0
HKD3_k127_2519426_11 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005549 366.0
HKD3_k127_2519426_12 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 373.0
HKD3_k127_2519426_13 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 332.0
HKD3_k127_2519426_14 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 306.0
HKD3_k127_2519426_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 293.0
HKD3_k127_2519426_16 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005933 245.0
HKD3_k127_2519426_17 Protoglobin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008156 258.0
HKD3_k127_2519426_18 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001649 256.0
HKD3_k127_2519426_19 Putative transmembrane protein (Alph_Pro_TM) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004509 241.0
HKD3_k127_2519426_2 Histidine kinase - - - 7.48e-216 685.0
HKD3_k127_2519426_20 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000001507 208.0
HKD3_k127_2519426_21 PP-loop superfamily ATPase - - - 0.000000000000000000000000000000000000000000000000001784 188.0
HKD3_k127_2519426_22 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000003467 175.0
HKD3_k127_2519426_23 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000001691 159.0
HKD3_k127_2519426_24 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000009081 152.0
HKD3_k127_2519426_25 Protein of unknown function DUF134 - - - 0.000000000000000000000000000000000000004409 154.0
HKD3_k127_2519426_26 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000001909 153.0
HKD3_k127_2519426_27 transposase IS116 IS110 IS902 family protein K07486 - - 0.000000000000000000000008865 102.0
HKD3_k127_2519426_28 phosphorelay signal transduction system - - - 0.00000000000000000000001593 104.0
HKD3_k127_2519426_29 protein with SCP PR1 domains - - - 0.00000000000000000000007801 105.0
HKD3_k127_2519426_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 6.5e-207 649.0
HKD3_k127_2519426_31 - - - - 0.0000001973 57.0
HKD3_k127_2519426_32 gas vesicle protein - - - 0.00006949 48.0
HKD3_k127_2519426_33 LytTr DNA-binding domain - - - 0.0003772 48.0
HKD3_k127_2519426_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 6.33e-204 644.0
HKD3_k127_2519426_5 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 2.782e-199 631.0
HKD3_k127_2519426_6 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 513.0
HKD3_k127_2519426_7 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 511.0
HKD3_k127_2519426_8 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008956 471.0
HKD3_k127_2519426_9 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 458.0
HKD3_k127_252455_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 570.0
HKD3_k127_252455_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 385.0
HKD3_k127_252455_10 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000005426 165.0
HKD3_k127_252455_11 MlaC protein K07323 - - 0.00000000000000000000000000000001227 134.0
HKD3_k127_252455_12 MlaC protein K07323 - - 0.000000000000000000000000000005598 128.0
HKD3_k127_252455_13 Transposase - - - 0.00000000000006798 72.0
HKD3_k127_252455_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 380.0
HKD3_k127_252455_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 359.0
HKD3_k127_252455_4 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009543 353.0
HKD3_k127_252455_5 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 329.0
HKD3_k127_252455_6 - - - - 0.00000000000000000000000000000000000000000000000000002468 195.0
HKD3_k127_252455_7 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000004417 190.0
HKD3_k127_252455_8 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000009457 194.0
HKD3_k127_252455_9 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000000003803 162.0
HKD3_k127_2554752_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 8.176e-200 631.0
HKD3_k127_2554752_1 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 411.0
HKD3_k127_2554752_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 287.0
HKD3_k127_2554752_3 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000000002381 183.0
HKD3_k127_2554752_4 - - - - 0.0000000000000000000000000003105 117.0
HKD3_k127_2554752_5 AMP-dependent synthetase and ligase K01895,K08295 - 6.2.1.1,6.2.1.32 0.000000000000000000000000008898 110.0
HKD3_k127_2554752_6 Domain of unknown function (DUF4926) - - - 0.0000000000000000000001317 99.0
HKD3_k127_2569084_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 2.526e-197 624.0
HKD3_k127_2569084_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 562.0
HKD3_k127_2569084_3 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 446.0
HKD3_k127_2569084_4 ErfK YbiS YcfS YnhG family protein K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 406.0
HKD3_k127_2569084_5 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 310.0
HKD3_k127_2572876_0 protein with a C-terminal OMP (outer membrane protein) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 560.0
HKD3_k127_2572876_1 Metallo-beta-lactamase superfamily domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 485.0
HKD3_k127_2572876_2 Protein of unknown function (DUF434) - - - 0.00000000000000000000000000000000000000000000000000000009852 204.0
HKD3_k127_2591664_0 cluster binding protein - - - 0.0 1007.0
HKD3_k127_2591664_1 PFAM Cysteine-rich domain K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 583.0
HKD3_k127_2591664_10 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000002962 194.0
HKD3_k127_2591664_11 Domain of unknown function (DUF296) K06934 - - 0.0000000000000000000000000000000000000000000574 165.0
HKD3_k127_2591664_12 MMPL family K07003 - - 0.0000000000000000000000000000000000002116 147.0
HKD3_k127_2591664_13 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000006327 145.0
HKD3_k127_2591664_14 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000003077 113.0
HKD3_k127_2591664_15 PFAM L-lactate permease K03303 - - 0.000000000000000000127 93.0
HKD3_k127_2591664_16 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD3_k127_2591664_17 transposase activity - - - 0.00000006405 61.0
HKD3_k127_2591664_18 Concanavalin A-like lectin/glucanases superfamily - - - 0.000005323 51.0
HKD3_k127_2591664_19 competence protein - - - 0.0001151 53.0
HKD3_k127_2591664_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 514.0
HKD3_k127_2591664_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004086 413.0
HKD3_k127_2591664_4 PFAM L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008643 340.0
HKD3_k127_2591664_5 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 327.0
HKD3_k127_2591664_6 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 299.0
HKD3_k127_2591664_7 FCD K05799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000214 275.0
HKD3_k127_2591664_8 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000005269 216.0
HKD3_k127_2591664_9 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000001059 194.0
HKD3_k127_2613520_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1147.0
HKD3_k127_2613520_1 ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 490.0
HKD3_k127_2613520_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 302.0
HKD3_k127_2613520_3 PFAM Peptidase M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 302.0
HKD3_k127_2613520_4 PFAM Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003199 256.0
HKD3_k127_2613520_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000456 138.0
HKD3_k127_2613520_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000001588 76.0
HKD3_k127_2618981_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0 1038.0
HKD3_k127_2618981_1 4Fe-4S dicluster domain - - - 5.372e-310 955.0
HKD3_k127_2618981_10 TIGRFAM cytochrome d oxidase, subunit II (cydB) K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 457.0
HKD3_k127_2618981_11 precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit K00595 - 2.1.1.132 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 457.0
HKD3_k127_2618981_12 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 434.0
HKD3_k127_2618981_13 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 417.0
HKD3_k127_2618981_14 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 400.0
HKD3_k127_2618981_15 PFAM cobalamin (vitamin B12) biosynthesis CbiG K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 398.0
HKD3_k127_2618981_16 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 383.0
HKD3_k127_2618981_17 SERine Proteinase INhibitors K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 382.0
HKD3_k127_2618981_18 Tetrapyrrole (Corrin/Porphyrin) Methylases K03394 - 2.1.1.130,2.1.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 354.0
HKD3_k127_2618981_19 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934,K13541,K21479 - 2.1.1.131,2.1.1.272,3.7.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 362.0
HKD3_k127_2618981_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.225e-218 695.0
HKD3_k127_2618981_20 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 338.0
HKD3_k127_2618981_21 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 336.0
HKD3_k127_2618981_22 PFAM Nucleoside recognition - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 335.0
HKD3_k127_2618981_23 Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 301.0
HKD3_k127_2618981_24 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007945 274.0
HKD3_k127_2618981_25 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000009388 263.0
HKD3_k127_2618981_26 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002545 263.0
HKD3_k127_2618981_27 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000002486 260.0
HKD3_k127_2618981_28 Precorrin-4 C(11)-methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000001205 237.0
HKD3_k127_2618981_29 NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001686 212.0
HKD3_k127_2618981_3 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 2.103e-212 667.0
HKD3_k127_2618981_30 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000009774 211.0
HKD3_k127_2618981_31 - - - - 0.00000000000000000000000000000000000000000000000000000005812 200.0
HKD3_k127_2618981_32 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000001634 194.0
HKD3_k127_2618981_33 Polysaccharide deacetylase K01452,K14659,K22278 - 3.5.1.104,3.5.1.41 0.0000000000000000000000000000000000000000000000002844 189.0
HKD3_k127_2618981_34 NAD+ binding K12410 - - 0.0000000000000000000000000000000000000000000003542 174.0
HKD3_k127_2618981_35 cobalt chelatase K02190 - 4.99.1.3 0.0000000000000000000000000000000000000000002333 169.0
HKD3_k127_2618981_36 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000001893 162.0
HKD3_k127_2618981_37 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.000000000000000000000000000000000000000005495 160.0
HKD3_k127_2618981_38 - - - - 0.0000000000000000000000000000007801 121.0
HKD3_k127_2618981_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00176,K00338 - 1.2.7.3,1.6.5.3 0.000000000000000000000000003787 112.0
HKD3_k127_2618981_4 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 6.921e-210 664.0
HKD3_k127_2618981_40 - - - - 0.0000000000000000000000001276 112.0
HKD3_k127_2618981_41 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000001574 106.0
HKD3_k127_2618981_42 - - - - 0.000000000000000000108 94.0
HKD3_k127_2618981_43 - - - - 0.0000000000002075 74.0
HKD3_k127_2618981_45 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000003408 57.0
HKD3_k127_2618981_46 Transposase is116 is110 is902 family K07486 - - 0.000001582 49.0
HKD3_k127_2618981_48 Desulfoferrodoxin K05919 - 1.15.1.2 0.00001225 51.0
HKD3_k127_2618981_49 methyltransferase - - - 0.0006651 43.0
HKD3_k127_2618981_5 PFAM Polysulphide reductase, NrfD K00185 - - 2.986e-197 622.0
HKD3_k127_2618981_6 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 7.345e-196 621.0
HKD3_k127_2618981_7 PFAM Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 585.0
HKD3_k127_2618981_8 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 499.0
HKD3_k127_2618981_9 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 494.0
HKD3_k127_2636548_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1069.0
HKD3_k127_2636548_1 Heat shock 70 kDa protein K04043 - - 0.0 1007.0
HKD3_k127_2636548_10 Uncharacterized protein conserved in bacteria (DUF2333) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 372.0
HKD3_k127_2636548_11 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 325.0
HKD3_k127_2636548_12 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003924 255.0
HKD3_k127_2636548_13 PFAM AMMECR1 domain protein K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000004665 232.0
HKD3_k127_2636548_14 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000000000149 218.0
HKD3_k127_2636548_15 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000297 197.0
HKD3_k127_2636548_16 - - - - 0.000000000000000000000000000000000000000000000000004591 184.0
HKD3_k127_2636548_17 TIGRFAM Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000002006 197.0
HKD3_k127_2636548_18 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000001321 171.0
HKD3_k127_2636548_19 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000663 156.0
HKD3_k127_2636548_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 5.425e-303 939.0
HKD3_k127_2636548_21 YHS domain protein - - - 0.0000000000000000000000000000004298 128.0
HKD3_k127_2636548_22 - - - - 0.00000000000000000000000002671 109.0
HKD3_k127_2636548_24 - - - - 0.00000000000000000000002872 102.0
HKD3_k127_2636548_25 - - - - 0.000000000000000000001777 98.0
HKD3_k127_2636548_26 Helix-turn-helix XRE-family like proteins K07334,K21498 - - 0.00000000000000000002906 93.0
HKD3_k127_2636548_28 Glycine-zipper domain - - - 0.0000000000000000369 83.0
HKD3_k127_2636548_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.06e-207 658.0
HKD3_k127_2636548_30 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD3_k127_2636548_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 539.0
HKD3_k127_2636548_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 503.0
HKD3_k127_2636548_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 449.0
HKD3_k127_2636548_7 PFAM Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 434.0
HKD3_k127_2636548_8 PFAM Extracellular ligand-binding receptor K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 439.0
HKD3_k127_2636548_9 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 387.0
HKD3_k127_2639844_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0 1009.0
HKD3_k127_2639844_1 PFAM Carbamoyltransferase K00612 - - 6.151e-306 947.0
HKD3_k127_2639844_10 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 459.0
HKD3_k127_2639844_11 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 455.0
HKD3_k127_2639844_12 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 443.0
HKD3_k127_2639844_13 PFAM polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 455.0
HKD3_k127_2639844_14 NAD dependent epimerase/dehydratase family K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 437.0
HKD3_k127_2639844_15 CoA-binding domain K03606 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 442.0
HKD3_k127_2639844_17 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007111 404.0
HKD3_k127_2639844_18 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 404.0
HKD3_k127_2639844_19 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 363.0
HKD3_k127_2639844_2 Carbamoyltransferase C-terminus K00612 - - 1.839e-239 754.0
HKD3_k127_2639844_20 lipopolysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 350.0
HKD3_k127_2639844_21 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005967 344.0
HKD3_k127_2639844_22 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 344.0
HKD3_k127_2639844_23 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 341.0
HKD3_k127_2639844_24 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 340.0
HKD3_k127_2639844_25 Glycosyl transferases group 1 K03208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 331.0
HKD3_k127_2639844_26 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 322.0
HKD3_k127_2639844_27 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 314.0
HKD3_k127_2639844_28 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 293.0
HKD3_k127_2639844_29 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 297.0
HKD3_k127_2639844_3 aminotransferase, class I and II K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 605.0
HKD3_k127_2639844_30 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000004873 257.0
HKD3_k127_2639844_31 -O-antigen K02847,K13009 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009894 269.0
HKD3_k127_2639844_32 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002087 259.0
HKD3_k127_2639844_33 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002382 246.0
HKD3_k127_2639844_34 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000001444 224.0
HKD3_k127_2639844_35 Acetyltransferase (Isoleucine patch superfamily) K03818 - - 0.00000000000000000000000000000000000000000000000000000000003187 214.0
HKD3_k127_2639844_36 ABC-type polysaccharide polyol phosphate transport system, ATPase component K01990,K09691,K09693 - 3.6.3.40 0.00000000000000000000000000000000000000000000000002049 194.0
HKD3_k127_2639844_37 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000005572 179.0
HKD3_k127_2639844_38 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000001567 160.0
HKD3_k127_2639844_39 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000009631 123.0
HKD3_k127_2639844_4 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 580.0
HKD3_k127_2639844_40 - - - - 0.0000000000000000000000000586 113.0
HKD3_k127_2639844_41 - - - - 0.0000000000000000006671 86.0
HKD3_k127_2639844_42 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.0000000000007446 80.0
HKD3_k127_2639844_43 ISXO2-like transposase domain - - - 0.000000003721 57.0
HKD3_k127_2639844_44 - - - - 0.0000001478 62.0
HKD3_k127_2639844_45 lipolytic protein G-D-S-L family - - - 0.0000003193 53.0
HKD3_k127_2639844_5 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 571.0
HKD3_k127_2639844_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 521.0
HKD3_k127_2639844_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 524.0
HKD3_k127_2639844_8 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 491.0
HKD3_k127_2639844_9 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 475.0
HKD3_k127_2660020_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 2.989e-298 957.0
HKD3_k127_2660020_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 1.333e-202 644.0
HKD3_k127_2660020_10 cell wall organization - - - 0.0001414 51.0
HKD3_k127_2660020_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 414.0
HKD3_k127_2660020_3 PFAM Alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 361.0
HKD3_k127_2660020_4 PFAM Carbamoyltransferase K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 350.0
HKD3_k127_2660020_5 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 319.0
HKD3_k127_2660020_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004051 244.0
HKD3_k127_2660020_7 PFAM Glycosyl transferase, group 1 K02844 - - 0.00000000000000000000000000000006092 127.0
HKD3_k127_2660020_8 Right handed beta helix region - - - 0.00000000000000000000000005025 117.0
HKD3_k127_268912_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 6.592e-208 666.0
HKD3_k127_268912_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 387.0
HKD3_k127_268912_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 326.0
HKD3_k127_268912_3 zinc ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000002451 223.0
HKD3_k127_268912_4 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000002808 188.0
HKD3_k127_268912_5 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000006077 174.0
HKD3_k127_268912_6 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000001451 159.0
HKD3_k127_268912_7 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 0.00000003243 59.0
HKD3_k127_269197_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.207e-223 696.0
HKD3_k127_269197_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 485.0
HKD3_k127_269197_10 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 296.0
HKD3_k127_269197_11 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001569 253.0
HKD3_k127_269197_12 PFAM NLP P60 protein K19223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000171 256.0
HKD3_k127_269197_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000004227 221.0
HKD3_k127_269197_14 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001067 224.0
HKD3_k127_269197_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
HKD3_k127_269197_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000005402 211.0
HKD3_k127_269197_17 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000000000000001303 216.0
HKD3_k127_269197_18 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000006521 200.0
HKD3_k127_269197_19 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003063 193.0
HKD3_k127_269197_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 451.0
HKD3_k127_269197_20 Ribosomal proteins 50S-L15, 50S-L18e, 60S-L27A K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000001078 180.0
HKD3_k127_269197_21 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000141 169.0
HKD3_k127_269197_22 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000214 171.0
HKD3_k127_269197_23 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003503 159.0
HKD3_k127_269197_24 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000001251 155.0
HKD3_k127_269197_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000005581 154.0
HKD3_k127_269197_26 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000000008016 139.0
HKD3_k127_269197_27 its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity) K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000037 139.0
HKD3_k127_269197_28 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000002883 136.0
HKD3_k127_269197_29 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000443 138.0
HKD3_k127_269197_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 375.0
HKD3_k127_269197_30 DoxX K15977 - - 0.000000000000000000000000000000005083 132.0
HKD3_k127_269197_31 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000006976 148.0
HKD3_k127_269197_32 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003882 123.0
HKD3_k127_269197_33 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000004066 113.0
HKD3_k127_269197_34 beta-lactamase domain protein - - - 0.0000000000000000000002024 109.0
HKD3_k127_269197_35 PFAM ribosomal protein L30 K02907 - - 0.00000000000000000302 85.0
HKD3_k127_269197_36 Putative amidoligase enzyme - - - 0.00000000000001757 85.0
HKD3_k127_269197_37 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000008664 69.0
HKD3_k127_269197_38 structural constituent of ribosome K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000006823 71.0
HKD3_k127_269197_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 361.0
HKD3_k127_269197_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 336.0
HKD3_k127_269197_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 327.0
HKD3_k127_269197_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 304.0
HKD3_k127_269197_8 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005233 327.0
HKD3_k127_269197_9 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 298.0
HKD3_k127_269277_0 PFAM Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 460.0
HKD3_k127_269277_1 SMART Elongator protein 3 MiaB NifB K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 391.0
HKD3_k127_269277_2 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 385.0
HKD3_k127_269277_3 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005506 282.0
HKD3_k127_269277_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000002196 220.0
HKD3_k127_269277_5 NTPase - - - 0.0000000000000000000000000000000001005 139.0
HKD3_k127_269277_6 granule-associated protein - - - 0.000000000000003353 79.0
HKD3_k127_2700214_0 Pyruvate:ferredoxin oxidoreductase core domain II K03737 - 1.2.7.1 0.0 1397.0
HKD3_k127_2700214_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1302.0
HKD3_k127_2700214_10 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000004152 145.0
HKD3_k127_2700214_11 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000005898 139.0
HKD3_k127_2700214_12 - - - - 0.000000000000000000001167 96.0
HKD3_k127_2700214_13 antisigma factor binding K03598 - - 0.0000000000000000006509 94.0
HKD3_k127_2700214_2 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 2.006e-202 647.0
HKD3_k127_2700214_3 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 477.0
HKD3_k127_2700214_4 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 304.0
HKD3_k127_2700214_5 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 312.0
HKD3_k127_2700214_6 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 286.0
HKD3_k127_2700214_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004259 277.0
HKD3_k127_2700214_8 DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000002047 221.0
HKD3_k127_2700214_9 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000002377 218.0
HKD3_k127_2757086_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1051.0
HKD3_k127_2757086_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 1.729e-293 911.0
HKD3_k127_2757086_10 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001383 284.0
HKD3_k127_2757086_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005155 259.0
HKD3_k127_2757086_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 256.0
HKD3_k127_2757086_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000004753 240.0
HKD3_k127_2757086_14 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000928 226.0
HKD3_k127_2757086_15 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000001301 203.0
HKD3_k127_2757086_16 - - - - 0.00000000000000000000000000000000000000000000001047 176.0
HKD3_k127_2757086_17 PFAM phosphotransferase KptA Tpt1 K07559 - - 0.0000000000000000000000000000000000000000089 163.0
HKD3_k127_2757086_18 - - - - 0.0000000000000000000000000000000000009018 146.0
HKD3_k127_2757086_19 Gram-negative-bacterium-type cell wall biogenesis - - - 0.000000000000000000000000000000000006329 145.0
HKD3_k127_2757086_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 1.711e-200 641.0
HKD3_k127_2757086_20 YGGT family K02221 - - 0.00000000000000000000000000000005233 130.0
HKD3_k127_2757086_21 Protein of unknown function (DUF498/DUF598) - - - 0.00000000000000000000000000004946 120.0
HKD3_k127_2757086_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.0000000000000000000000000005092 116.0
HKD3_k127_2757086_23 DUF167 K09131 - - 0.0000000000000000000000008831 106.0
HKD3_k127_2757086_24 regulatory protein, FmdB family - - - 0.0000000000000000000003445 99.0
HKD3_k127_2757086_25 Outer membrane lipoprotein Slp family K07285 - - 0.00000000006143 70.0
HKD3_k127_2757086_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 394.0
HKD3_k127_2757086_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 389.0
HKD3_k127_2757086_5 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 384.0
HKD3_k127_2757086_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 343.0
HKD3_k127_2757086_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 353.0
HKD3_k127_2757086_8 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 315.0
HKD3_k127_2757086_9 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 294.0
HKD3_k127_2802877_0 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 2.32e-291 905.0
HKD3_k127_2802877_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 3.843e-261 824.0
HKD3_k127_2802877_10 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 451.0
HKD3_k127_2802877_11 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
HKD3_k127_2802877_12 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 375.0
HKD3_k127_2802877_13 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 354.0
HKD3_k127_2802877_14 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 327.0
HKD3_k127_2802877_15 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 323.0
HKD3_k127_2802877_16 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 320.0
HKD3_k127_2802877_17 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 317.0
HKD3_k127_2802877_18 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 315.0
HKD3_k127_2802877_19 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000105 280.0
HKD3_k127_2802877_2 PFAM Transketolase K00615 - 2.2.1.1 4.108e-257 806.0
HKD3_k127_2802877_20 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
HKD3_k127_2802877_21 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000002233 271.0
HKD3_k127_2802877_22 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002098 257.0
HKD3_k127_2802877_23 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000001464 252.0
HKD3_k127_2802877_24 Binding-protein-dependent transport system inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
HKD3_k127_2802877_25 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000036 240.0
HKD3_k127_2802877_26 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000001636 235.0
HKD3_k127_2802877_27 - - - - 0.0000000000000000000000000000000000000000000000000000000000009803 214.0
HKD3_k127_2802877_28 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000004927 212.0
HKD3_k127_2802877_29 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000004712 214.0
HKD3_k127_2802877_3 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.089e-208 660.0
HKD3_k127_2802877_30 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000002049 192.0
HKD3_k127_2802877_31 sodium-dependent phosphate transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000009973 186.0
HKD3_k127_2802877_32 Cytochrome b5-like Heme/Steroid binding domain - - - 0.0000000000000000000000000000000000000000002717 162.0
HKD3_k127_2802877_33 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000002135 163.0
HKD3_k127_2802877_34 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000001204 151.0
HKD3_k127_2802877_35 PFAM Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.000000000000000000000000000000003941 133.0
HKD3_k127_2802877_36 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000003208 132.0
HKD3_k127_2802877_4 Response regulator receiver - - - 6.895e-197 622.0
HKD3_k127_2802877_5 PFAM ATP-binding region, ATPase domain protein - - - 9.077e-195 618.0
HKD3_k127_2802877_6 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 597.0
HKD3_k127_2802877_7 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 544.0
HKD3_k127_2802877_8 Type II and III secretion system protein K02280 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 514.0
HKD3_k127_2802877_9 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 461.0
HKD3_k127_2935560_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008231 382.0
HKD3_k127_2935560_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 372.0
HKD3_k127_2935965_0 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000001368 232.0
HKD3_k127_2935965_1 Belongs to the UPF0296 family K09777 - - 0.00000000000000000000006871 99.0
HKD3_k127_318116_0 PFAM Nickel-dependent hydrogenase, large subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 577.0
HKD3_k127_318116_1 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 434.0
HKD3_k127_318116_2 2 iron, 2 sulfur cluster binding K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 378.0
HKD3_k127_318116_3 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 335.0
HKD3_k127_318116_4 cell adhesion involved in biofilm formation K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002186 276.0
HKD3_k127_318116_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.00000000000000000000000000000000000000002955 158.0
HKD3_k127_318116_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000004056 152.0
HKD3_k127_318116_7 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000002284 133.0
HKD3_k127_318116_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.00000002535 55.0
HKD3_k127_3188255_0 DEAD DEAH box helicase K06877 - - 0.0 1277.0
HKD3_k127_3188255_1 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 590.0
HKD3_k127_3188255_10 SMART Transcription regulator, AsnC-type - - - 0.0000000000000000000000000000000000000000000000000000000000001772 216.0
HKD3_k127_3188255_11 AMP binding - - - 0.0000000000000000000000000000000000000000000000001766 180.0
HKD3_k127_3188255_12 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000002201 176.0
HKD3_k127_3188255_13 peroxiredoxin activity - - - 0.00000000000000000000000000000001342 134.0
HKD3_k127_3188255_14 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001205 119.0
HKD3_k127_3188255_15 - - - - 0.00000000000000000000000000005437 117.0
HKD3_k127_3188255_16 Right handed beta helix region - - - 0.00000000000000000000000000009498 126.0
HKD3_k127_3188255_18 peroxiredoxin activity - - - 0.000000000000000000000001909 110.0
HKD3_k127_3188255_19 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000004866 90.0
HKD3_k127_3188255_2 Glycosyl transferase family group 2 K00752,K11936 - 2.4.1.212 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 590.0
HKD3_k127_3188255_3 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 593.0
HKD3_k127_3188255_4 SMART Elongator protein 3 MiaB NifB K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 538.0
HKD3_k127_3188255_5 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 479.0
HKD3_k127_3188255_6 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 347.0
HKD3_k127_3188255_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 312.0
HKD3_k127_3188255_8 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 322.0
HKD3_k127_3188255_9 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006447 260.0
HKD3_k127_324708_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 617.0
HKD3_k127_324708_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 614.0
HKD3_k127_324708_10 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 293.0
HKD3_k127_324708_11 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000001187 251.0
HKD3_k127_324708_12 Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000946 212.0
HKD3_k127_324708_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000002218 187.0
HKD3_k127_324708_14 Glycoprotease family K01409,K14742 - 2.3.1.234 0.000000000000000000000000000000000000000000001205 177.0
HKD3_k127_324708_15 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000003132 147.0
HKD3_k127_324708_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000001571 141.0
HKD3_k127_324708_17 regulatory protein, FmdB family - - - 0.000000000000000000000000000000000001808 143.0
HKD3_k127_324708_19 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000001104 117.0
HKD3_k127_324708_2 PFAM Peptidase M20 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 516.0
HKD3_k127_324708_21 snoRNA binding - - - 0.000000000000001707 79.0
HKD3_k127_324708_22 recombinase activity - - - 0.00000003499 62.0
HKD3_k127_324708_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 497.0
HKD3_k127_324708_4 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 465.0
HKD3_k127_324708_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 454.0
HKD3_k127_324708_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 443.0
HKD3_k127_324708_7 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 429.0
HKD3_k127_324708_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 389.0
HKD3_k127_324708_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 374.0
HKD3_k127_3439934_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.331e-237 741.0
HKD3_k127_3439934_1 aminotransferase, class I and II K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 558.0
HKD3_k127_3439934_10 LD-carboxypeptidase K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007935 309.0
HKD3_k127_3439934_11 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 286.0
HKD3_k127_3439934_12 PFAM Aminotransferase, class IV K00826,K02619 - 2.6.1.42,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 289.0
HKD3_k127_3439934_13 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000168 288.0
HKD3_k127_3439934_14 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 288.0
HKD3_k127_3439934_15 ResB-like family K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001864 291.0
HKD3_k127_3439934_16 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000003228 234.0
HKD3_k127_3439934_17 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000001497 225.0
HKD3_k127_3439934_18 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000000002397 228.0
HKD3_k127_3439934_19 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000006188 223.0
HKD3_k127_3439934_2 PFAM Anthranilate synthase component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 475.0
HKD3_k127_3439934_20 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
HKD3_k127_3439934_21 PFAM NUDIX domain - - - 0.0000000000000000000000000000000000000000000001578 174.0
HKD3_k127_3439934_22 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000219 171.0
HKD3_k127_3439934_23 - - - - 0.0000000000000000000000000000000000000000000006379 173.0
HKD3_k127_3439934_24 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000003222 168.0
HKD3_k127_3439934_25 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000003228 154.0
HKD3_k127_3439934_26 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000006221 160.0
HKD3_k127_3439934_27 - - - - 0.000000000000000000000000000000000001384 144.0
HKD3_k127_3439934_28 Universal stress protein K06149 - - 0.000000000000000000000000000000000003986 141.0
HKD3_k127_3439934_29 - - - - 0.00000000000000000000000005109 110.0
HKD3_k127_3439934_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 466.0
HKD3_k127_3439934_30 lyase activity - - - 0.0000000000000000000000007634 107.0
HKD3_k127_3439934_31 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000004433 103.0
HKD3_k127_3439934_32 Histidine kinase - - - 0.000000000000000000003003 97.0
HKD3_k127_3439934_33 - - - - 0.000000000000000000009296 95.0
HKD3_k127_3439934_34 PFAM Thioredoxin K03671 - - 0.0000000000001436 76.0
HKD3_k127_3439934_35 Multicopper oxidase - - - 0.0000000000005964 75.0
HKD3_k127_3439934_36 AhpC/TSA family - - - 0.000000000003169 68.0
HKD3_k127_3439934_39 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000003244 56.0
HKD3_k127_3439934_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 417.0
HKD3_k127_3439934_5 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 412.0
HKD3_k127_3439934_6 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 391.0
HKD3_k127_3439934_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 364.0
HKD3_k127_3439934_8 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 370.0
HKD3_k127_3439934_9 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 338.0
HKD3_k127_3569912_0 Amino acid permease - - - 8.077e-254 796.0
HKD3_k127_3569912_1 Amino acid permease - - - 1.358e-237 750.0
HKD3_k127_3569912_10 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 338.0
HKD3_k127_3569912_11 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000446 293.0
HKD3_k127_3569912_12 PFAM ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009212 289.0
HKD3_k127_3569912_13 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003112 277.0
HKD3_k127_3569912_14 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009747 270.0
HKD3_k127_3569912_15 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004787 252.0
HKD3_k127_3569912_16 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000593 173.0
HKD3_k127_3569912_17 PFAM S23 ribosomal protein - - - 0.000000000000000000000000000000000001002 141.0
HKD3_k127_3569912_18 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000009479 128.0
HKD3_k127_3569912_19 PFAM Cold-shock protein, DNA-binding K03704 - - 0.000000000000000000000000000002722 120.0
HKD3_k127_3569912_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 4.155e-231 729.0
HKD3_k127_3569912_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 468.0
HKD3_k127_3569912_4 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005062 416.0
HKD3_k127_3569912_5 transport system permease K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 411.0
HKD3_k127_3569912_6 PFAM CobQ CobB MinD ParA nucleotide binding domain K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 396.0
HKD3_k127_3569912_7 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008419 400.0
HKD3_k127_3569912_8 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 388.0
HKD3_k127_3569912_9 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009896 368.0
HKD3_k127_3649581_0 Belongs to the glycosyl hydrolase 57 family - - - 1.626e-274 867.0
HKD3_k127_3649581_1 Radical SAM superfamily K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 561.0
HKD3_k127_3649581_10 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000005612 259.0
HKD3_k127_3649581_11 ThiF family K03148,K21147 - 2.7.7.73,2.7.7.80,2.8.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000001123 249.0
HKD3_k127_3649581_12 Sugar fermentation stimulation protein K06206 - - 0.0000000000000000000000000000000000000000000000001185 186.0
HKD3_k127_3649581_13 Cyclophilin-like K09143 - - 0.000000000000000000000000000002231 124.0
HKD3_k127_3649581_14 TIGRFAM regulatory protein, FmdB - - - 0.0000000000000000000000000434 109.0
HKD3_k127_3649581_15 - - - - 0.0000000000000000000001124 105.0
HKD3_k127_3649581_16 - - - - 0.0001986 52.0
HKD3_k127_3649581_17 thiamine biosynthesis protein ThiS K03154 - - 0.0007844 42.0
HKD3_k127_3649581_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 474.0
HKD3_k127_3649581_3 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007973 462.0
HKD3_k127_3649581_4 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 381.0
HKD3_k127_3649581_5 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 365.0
HKD3_k127_3649581_6 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 356.0
HKD3_k127_3649581_7 Biotin and Thiamin Synthesis associated domain K03150 - 4.1.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 346.0
HKD3_k127_3649581_8 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 331.0
HKD3_k127_3649581_9 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 312.0
HKD3_k127_3814799_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1510.0
HKD3_k127_3814799_1 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1191.0
HKD3_k127_3814799_10 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 303.0
HKD3_k127_3814799_11 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000946 284.0
HKD3_k127_3814799_12 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008996 248.0
HKD3_k127_3814799_13 DUF3160 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002707 263.0
HKD3_k127_3814799_14 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003484 234.0
HKD3_k127_3814799_15 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000004078 216.0
HKD3_k127_3814799_16 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000007927 119.0
HKD3_k127_3814799_17 Putative Tad-like Flp pilus-assembly - - - 0.0000000000000000000000000003918 126.0
HKD3_k127_3814799_18 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000558 112.0
HKD3_k127_3814799_19 FAD dependent oxidoreductase - - - 0.0000000000000000000001296 98.0
HKD3_k127_3814799_2 Signal transduction histidine kinase - - - 7.444e-305 951.0
HKD3_k127_3814799_20 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000002562 97.0
HKD3_k127_3814799_21 Peptidase family M23 K21472 - - 0.00000000000000004834 94.0
HKD3_k127_3814799_22 Phage integrase family K03733 - - 0.00000000000000006178 85.0
HKD3_k127_3814799_23 cheY-homologous receiver domain - - - 0.0000000000000002429 90.0
HKD3_k127_3814799_24 Fibronectin type III domain - - - 0.0000000000005175 82.0
HKD3_k127_3814799_25 DNA integration K14059 - - 0.0000001547 53.0
HKD3_k127_3814799_3 Molydopterin dinucleotide binding domain K00123,K05299 - 1.17.1.10,1.17.1.9 5.431e-244 763.0
HKD3_k127_3814799_4 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 6.798e-215 678.0
HKD3_k127_3814799_5 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 426.0
HKD3_k127_3814799_6 PFAM glycine cleavage H-protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 405.0
HKD3_k127_3814799_7 Memo-like protein K06990,K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 395.0
HKD3_k127_3814799_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 305.0
HKD3_k127_3814799_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 302.0
HKD3_k127_3838714_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1171.0
HKD3_k127_3838714_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1152.0
HKD3_k127_3838714_10 metal-dependent membrane protease - - - 0.00000000000000000000000000000000000000000000000000000000000000003255 233.0
HKD3_k127_3838714_11 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000000000000000007613 235.0
HKD3_k127_3838714_12 Diguanylate cyclase K21084 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000003109 241.0
HKD3_k127_3838714_13 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000126 228.0
HKD3_k127_3838714_14 Type II secretion system K12511 - - 0.00000000000000000000000000000000000000000000000000157 194.0
HKD3_k127_3838714_15 type II secretion system protein K12510 - - 0.0000000000000000000000000000000000000000000000004227 188.0
HKD3_k127_3838714_16 Pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000000006348 170.0
HKD3_k127_3838714_17 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000004513 161.0
HKD3_k127_3838714_18 pfkB family carbohydrate kinase K00852 - 2.7.1.15 0.000000000000000000000000000000000000000008411 166.0
HKD3_k127_3838714_19 AAA domain K02282 - - 0.000000000000000000000000000000000000004502 160.0
HKD3_k127_3838714_2 SMART Elongator protein 3 MiaB NifB - - - 3.112e-230 720.0
HKD3_k127_3838714_20 PFAM Response regulator receiver domain - - - 0.00000000000000000000000003309 124.0
HKD3_k127_3838714_21 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000006992 103.0
HKD3_k127_3838714_22 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000002983 93.0
HKD3_k127_3838714_23 PFAM Peptidase A24A, prepilin type IV K02278 - 3.4.23.43 0.00000000000000001817 90.0
HKD3_k127_3838714_24 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000001126 72.0
HKD3_k127_3838714_25 PFAM TadE family protein - - - 0.00000000006326 69.0
HKD3_k127_3838714_26 - - - - 0.0000000003053 61.0
HKD3_k127_3838714_27 Flp/Fap pilin component K02651 - - 0.000000003503 60.0
HKD3_k127_3838714_3 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 553.0
HKD3_k127_3838714_4 Secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 529.0
HKD3_k127_3838714_5 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 428.0
HKD3_k127_3838714_6 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 410.0
HKD3_k127_3838714_7 YdjC-like protein K03478 - 3.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 315.0
HKD3_k127_3838714_8 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 302.0
HKD3_k127_3838714_9 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000141 246.0
HKD3_k127_3847843_0 TIGRFAM Nitrogenase molybdenum-iron protein alpha chain K02586 - 1.18.6.1 7.506e-312 960.0
HKD3_k127_3847843_1 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 518.0
HKD3_k127_3847843_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 345.0
HKD3_k127_3847843_3 Belongs to the P(II) protein family K02590 - - 0.0000000000000000000000000000000000000000000000000000000000001291 215.0
HKD3_k127_3847843_4 Belongs to the P(II) protein family K02589 - - 0.0000000000000000000000000000000000000000000000000000000000241 209.0
HKD3_k127_3847843_5 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 0.000000000000000000000000000006487 119.0
HKD3_k127_3847843_6 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 0.00000000000000000000008274 97.0
HKD3_k127_3869983_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1235.0
HKD3_k127_3869983_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 2.923e-199 633.0
HKD3_k127_3869983_11 L,D-transpeptidase catalytic domain - - - 0.000000002523 68.0
HKD3_k127_3869983_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 436.0
HKD3_k127_3869983_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 423.0
HKD3_k127_3869983_4 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001148 224.0
HKD3_k127_3869983_5 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000002221 169.0
HKD3_k127_3869983_6 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000007416 166.0
HKD3_k127_3869983_7 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000274 151.0
HKD3_k127_3869983_9 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000004563 108.0
HKD3_k127_389068_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 2.878e-294 913.0
HKD3_k127_389068_1 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 563.0
HKD3_k127_389068_2 ferredoxin oxidoreductase beta subunit K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 563.0
HKD3_k127_389068_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000008706 227.0
HKD3_k127_389068_4 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000152 75.0
HKD3_k127_3909525_0 Ftsk_gamma K03466 - - 2.135e-261 828.0
HKD3_k127_3909525_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.843e-201 634.0
HKD3_k127_3909525_10 Methyltransferase domain K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000004519 185.0
HKD3_k127_3909525_11 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000001378 136.0
HKD3_k127_3909525_12 - - - - 0.00000000000000000000001024 104.0
HKD3_k127_3909525_13 HD domain - - - 0.00000000000000000005139 102.0
HKD3_k127_3909525_14 - - - - 0.0000000000006027 71.0
HKD3_k127_3909525_2 Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 506.0
HKD3_k127_3909525_3 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 389.0
HKD3_k127_3909525_4 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012,K16180 - 2.8.1.6,5.4.99.58 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 358.0
HKD3_k127_3909525_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 341.0
HKD3_k127_3909525_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 309.0
HKD3_k127_3909525_7 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 301.0
HKD3_k127_3909525_8 AAA domain K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 295.0
HKD3_k127_3909525_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 241.0
HKD3_k127_3938700_0 Belongs to the UbiD family K03182 - 4.1.1.98 1.029e-255 794.0
HKD3_k127_3938700_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K11779,K11784,K18285 - 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 535.0
HKD3_k127_3938700_10 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000001426 201.0
HKD3_k127_3938700_11 Transcriptional regulator, TetR family - - - 0.00000000000000000000000005252 109.0
HKD3_k127_3938700_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 471.0
HKD3_k127_3938700_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 430.0
HKD3_k127_3938700_4 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 413.0
HKD3_k127_3938700_5 Amidohydrolase family K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 399.0
HKD3_k127_3938700_6 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 298.0
HKD3_k127_3938700_7 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003655 272.0
HKD3_k127_3938700_8 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000002024 260.0
HKD3_k127_3938700_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.0000000000000000000000000000000000000000000000000000000001404 213.0
HKD3_k127_3996006_0 pyruvate K01571,K01958,K01960 - 4.1.1.3,6.4.1.1 2.019e-195 619.0
HKD3_k127_3996006_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 500.0
HKD3_k127_3996006_2 phosphorelay sensor kinase activity K01768,K07315 - 3.1.3.3,4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005933 413.0
HKD3_k127_3996006_3 Chalcone and stilbene synthases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 374.0
HKD3_k127_3996006_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008459 263.0
HKD3_k127_3996006_5 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001422 267.0
HKD3_k127_3996006_6 Glyoxalase-like domain K01759,K08234 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000001949 218.0
HKD3_k127_3996006_7 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000007981 198.0
HKD3_k127_3996006_8 YHS domain - - - 0.0000000000005553 73.0
HKD3_k127_3996006_9 ISXO2-like transposase domain - - - 0.000000000001779 67.0
HKD3_k127_4042328_0 Histidine kinase K07315 - 3.1.3.3 9.527e-240 761.0
HKD3_k127_4042328_1 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 434.0
HKD3_k127_4042328_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000001365 122.0
HKD3_k127_4042328_11 PFAM PQQ enzyme repeat - - - 0.000000000000000000001732 100.0
HKD3_k127_4042328_12 AntiSigma factor - - - 0.0000008084 59.0
HKD3_k127_4042328_2 Major Facilitator Superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 429.0
HKD3_k127_4042328_3 NMT1/THI5 like K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 346.0
HKD3_k127_4042328_4 PFAM HPP family K07168 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
HKD3_k127_4042328_5 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
HKD3_k127_4042328_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000002044 207.0
HKD3_k127_4042328_7 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000871 199.0
HKD3_k127_4042328_8 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000001288 177.0
HKD3_k127_4042328_9 - - - - 0.000000000000000000000000000000000001661 143.0
HKD3_k127_4070579_0 Beta-lactamase - - - 3.857e-266 835.0
HKD3_k127_4070579_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 350.0
HKD3_k127_4093743_0 Translation-initiation factor 2 K02519 - - 2.078e-225 729.0
HKD3_k127_4093743_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 600.0
HKD3_k127_4093743_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 308.0
HKD3_k127_4093743_3 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000002388 194.0
HKD3_k127_4093743_4 - - - - 0.000000000000000000000000000000000000000000000002884 174.0
HKD3_k127_4093743_5 RimP C-terminal SH3 domain K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000005771 156.0
HKD3_k127_4093743_6 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000000003454 98.0
HKD3_k127_4141544_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 5.905e-301 928.0
HKD3_k127_4141544_1 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 451.0
HKD3_k127_4141544_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006504 273.0
HKD3_k127_4141544_11 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006136 246.0
HKD3_k127_4141544_12 Rubrerythrin - - - 0.000000000000000000000000000000000000000002461 161.0
HKD3_k127_4141544_13 NUDIX domain - - - 0.000000000000000000000000000000000000000005705 161.0
HKD3_k127_4141544_14 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000007821 155.0
HKD3_k127_4141544_15 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000000004126 114.0
HKD3_k127_4141544_16 Coenzyme A transferase K01028,K01039 - 2.8.3.12,2.8.3.5 0.0000000000000000000000614 104.0
HKD3_k127_4141544_17 Coenzyme A transferase K01039,K01040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.8.3.12 0.00000000000001113 78.0
HKD3_k127_4141544_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000006961 72.0
HKD3_k127_4141544_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 426.0
HKD3_k127_4141544_3 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 366.0
HKD3_k127_4141544_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 347.0
HKD3_k127_4141544_5 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 343.0
HKD3_k127_4141544_6 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 314.0
HKD3_k127_4141544_7 GTP binding K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 294.0
HKD3_k127_4141544_8 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 291.0
HKD3_k127_4141544_9 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 288.0
HKD3_k127_4196026_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1328.0
HKD3_k127_4196026_1 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 4.463e-211 688.0
HKD3_k127_4196026_10 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000002194 255.0
HKD3_k127_4196026_11 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000004855 230.0
HKD3_k127_4196026_12 choline dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000005721 214.0
HKD3_k127_4196026_13 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000000000000000000000000000000000006599 219.0
HKD3_k127_4196026_14 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000000000000000009928 199.0
HKD3_k127_4196026_15 PFAM UBA THIF-type NAD FAD binding - - - 0.0000000000000000000000000000000000000000000000004907 186.0
HKD3_k127_4196026_16 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000005389 71.0
HKD3_k127_4196026_2 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 411.0
HKD3_k127_4196026_3 dihydroorotate dehydrogenase activity K00226,K00254,K02823,K17828 - 1.3.1.14,1.3.5.2,1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 393.0
HKD3_k127_4196026_4 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 372.0
HKD3_k127_4196026_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 316.0
HKD3_k127_4196026_6 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007496 315.0
HKD3_k127_4196026_7 amine dehydrogenase activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 301.0
HKD3_k127_4196026_8 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006991 284.0
HKD3_k127_4196026_9 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001052 274.0
HKD3_k127_4436356_0 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 486.0
HKD3_k127_4436356_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 398.0
HKD3_k127_4436356_10 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000002462 52.0
HKD3_k127_4436356_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008082 380.0
HKD3_k127_4436356_3 TIGRFAM hydrolase, TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 335.0
HKD3_k127_4436356_4 Phosphodiester glycosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 293.0
HKD3_k127_4436356_5 PFAM MgtC SapB transporter K07507 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
HKD3_k127_4436356_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000865 240.0
HKD3_k127_4436356_7 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000001297 219.0
HKD3_k127_4436356_8 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.000000000000000000000000000000000000000003624 163.0
HKD3_k127_4504206_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009425 516.0
HKD3_k127_4504206_1 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 395.0
HKD3_k127_4504206_10 competence protein - - - 0.00000000000000000000000000000000005401 143.0
HKD3_k127_4504206_11 - - - - 0.0000000000000000000000000000000002677 144.0
HKD3_k127_4504206_12 Sh3 type 3 domain protein K03642,K07184 - - 0.000000000000000000000001929 113.0
HKD3_k127_4504206_13 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000001958 87.0
HKD3_k127_4504206_14 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.0000000000001315 78.0
HKD3_k127_4504206_15 Bacterial SH3 domain homologues - - - 0.00009838 53.0
HKD3_k127_4504206_2 Phosphoesterase RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 395.0
HKD3_k127_4504206_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002257 282.0
HKD3_k127_4504206_4 Pfam:DUF162 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002146 276.0
HKD3_k127_4504206_5 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000002641 228.0
HKD3_k127_4504206_6 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000008698 205.0
HKD3_k127_4504206_7 DsrE/DsrF-like family K06039 - - 0.0000000000000000000000000000000000000000000000000762 179.0
HKD3_k127_4504206_8 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.00000000000000000000000000000000000000000004293 166.0
HKD3_k127_4504206_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000005663 144.0
HKD3_k127_4563227_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.961e-232 722.0
HKD3_k127_4563227_1 PFAM Radical SAM - - - 4.05e-227 717.0
HKD3_k127_4563227_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 511.0
HKD3_k127_4563227_11 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 496.0
HKD3_k127_4563227_12 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 487.0
HKD3_k127_4563227_13 Protein of unknown function (DUF933) K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 458.0
HKD3_k127_4563227_14 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 463.0
HKD3_k127_4563227_15 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 420.0
HKD3_k127_4563227_16 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 401.0
HKD3_k127_4563227_17 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 381.0
HKD3_k127_4563227_18 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 364.0
HKD3_k127_4563227_19 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 350.0
HKD3_k127_4563227_2 Endoribonuclease that initiates mRNA decay K18682 - - 5.758e-225 710.0
HKD3_k127_4563227_20 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 337.0
HKD3_k127_4563227_21 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 317.0
HKD3_k127_4563227_22 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002141 279.0
HKD3_k127_4563227_23 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005918 267.0
HKD3_k127_4563227_24 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000002861 232.0
HKD3_k127_4563227_25 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004857 239.0
HKD3_k127_4563227_26 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000000000000000000000000000001244 222.0
HKD3_k127_4563227_27 Essential cell division protein K03589 - - 0.000000000000000000000000000000000000000000000000000000000001032 222.0
HKD3_k127_4563227_28 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000001706 214.0
HKD3_k127_4563227_29 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000003812 211.0
HKD3_k127_4563227_3 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 3.985e-223 713.0
HKD3_k127_4563227_30 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000007432 205.0
HKD3_k127_4563227_31 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000008993 199.0
HKD3_k127_4563227_32 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000000000000000000000000000000000000002417 182.0
HKD3_k127_4563227_33 Rubrerythrin K19824 - - 0.000000000000000000000000000000000000000000000004369 177.0
HKD3_k127_4563227_34 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000006819 176.0
HKD3_k127_4563227_35 Belongs to the Fur family K09825,K22297 - - 0.000000000000000000000000000000000000000144 154.0
HKD3_k127_4563227_36 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.000000000000000000000000000000000044 136.0
HKD3_k127_4563227_37 lipolytic protein G-D-S-L family - - - 0.00000000000000000000002267 113.0
HKD3_k127_4563227_38 PFAM Glutamine amidotransferase, class-II - - - 0.000000000000000000002016 103.0
HKD3_k127_4563227_39 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000002113 100.0
HKD3_k127_4563227_4 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 7.42e-196 624.0
HKD3_k127_4563227_40 Protein of unknown function (DUF559) - - - 0.000000000000000007089 84.0
HKD3_k127_4563227_41 Protein of unknown function (DUF2442) - - - 0.000000000000001089 78.0
HKD3_k127_4563227_42 nuclease activity K06218 - - 0.000000000000004286 78.0
HKD3_k127_4563227_43 Protein of unknown function (DUF559) - - - 0.0000000004199 61.0
HKD3_k127_4563227_44 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000001953 63.0
HKD3_k127_4563227_45 Regulatory protein, FmdB family - - - 0.00000002557 59.0
HKD3_k127_4563227_48 Belongs to the Fur family K03711 - - 0.00000007399 59.0
HKD3_k127_4563227_49 Protein of unknown function (DUF1566) - - - 0.0000002249 59.0
HKD3_k127_4563227_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 574.0
HKD3_k127_4563227_50 - - - - 0.000006696 52.0
HKD3_k127_4563227_51 Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine K07008 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006518,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006577,GO:0006578,GO:0006725,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016020,GO:0016053,GO:0016054,GO:0019439,GO:0019752,GO:0032991,GO:0034641,GO:0042219,GO:0042398,GO:0043171,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0051187,GO:0052698,GO:0052699,GO:0052701,GO:0052703,GO:0052704,GO:0052708,GO:0052803,GO:0052805,GO:0061672,GO:0071704,GO:0071944,GO:0097164,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902494,GO:1905368 3.5.1.118 0.0003582 51.0
HKD3_k127_4563227_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008765,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 548.0
HKD3_k127_4563227_7 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 542.0
HKD3_k127_4563227_8 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 535.0
HKD3_k127_4563227_9 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 526.0
HKD3_k127_4863158_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1361.0
HKD3_k127_4863158_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1148.0
HKD3_k127_4863158_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 538.0
HKD3_k127_4863158_11 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006496 520.0
HKD3_k127_4863158_12 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 508.0
HKD3_k127_4863158_13 domain, Protein K15125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 519.0
HKD3_k127_4863158_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 495.0
HKD3_k127_4863158_15 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 494.0
HKD3_k127_4863158_16 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 480.0
HKD3_k127_4863158_17 Multicopper - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 484.0
HKD3_k127_4863158_18 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 452.0
HKD3_k127_4863158_19 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 425.0
HKD3_k127_4863158_2 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 2.265e-275 861.0
HKD3_k127_4863158_20 PFAM Transketolase, C-terminal domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 396.0
HKD3_k127_4863158_21 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 389.0
HKD3_k127_4863158_22 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 380.0
HKD3_k127_4863158_23 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 381.0
HKD3_k127_4863158_24 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 373.0
HKD3_k127_4863158_25 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 352.0
HKD3_k127_4863158_26 PFAM Glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 360.0
HKD3_k127_4863158_27 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 334.0
HKD3_k127_4863158_28 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 332.0
HKD3_k127_4863158_29 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 336.0
HKD3_k127_4863158_3 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 5.906e-264 818.0
HKD3_k127_4863158_30 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 334.0
HKD3_k127_4863158_31 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 333.0
HKD3_k127_4863158_32 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 315.0
HKD3_k127_4863158_33 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 304.0
HKD3_k127_4863158_34 PFAM NAD dependent epimerase dehydratase family K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 298.0
HKD3_k127_4863158_35 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 286.0
HKD3_k127_4863158_36 DNA polymerase alpha chain like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 276.0
HKD3_k127_4863158_37 domain, Protein K15125 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000282 297.0
HKD3_k127_4863158_38 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002101 265.0
HKD3_k127_4863158_39 PFAM Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000177 267.0
HKD3_k127_4863158_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.065e-222 698.0
HKD3_k127_4863158_40 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001458 232.0
HKD3_k127_4863158_41 NIL - - - 0.00000000000000000000000000000000000000000000000000000000000000005197 229.0
HKD3_k127_4863158_42 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000002024 226.0
HKD3_k127_4863158_43 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000006336 223.0
HKD3_k127_4863158_44 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000003554 200.0
HKD3_k127_4863158_45 Haloacid dehalogenase-like hydrolase K20866 - 3.1.3.10 0.0000000000000000000000000000000000000000000000000000001678 200.0
HKD3_k127_4863158_46 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000001108 198.0
HKD3_k127_4863158_47 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.000000000000000000000000000000000000000000000000000001969 195.0
HKD3_k127_4863158_48 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000001539 184.0
HKD3_k127_4863158_49 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000001857 175.0
HKD3_k127_4863158_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 4.67e-213 670.0
HKD3_k127_4863158_50 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000003717 166.0
HKD3_k127_4863158_52 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000000000000000000000002771 154.0
HKD3_k127_4863158_53 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000000000185 137.0
HKD3_k127_4863158_54 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000001207 133.0
HKD3_k127_4863158_55 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.000000000000000000000000000003241 123.0
HKD3_k127_4863158_56 PFAM Methylamine - - - 0.0000000000000000000000000000442 123.0
HKD3_k127_4863158_57 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.0000000000000000000000000001889 123.0
HKD3_k127_4863158_58 Belongs to the MtfA family K09933 - - 0.00000000000000000000000007647 109.0
HKD3_k127_4863158_59 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000008011 109.0
HKD3_k127_4863158_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 2.638e-212 669.0
HKD3_k127_4863158_60 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000001301 80.0
HKD3_k127_4863158_62 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000001873 69.0
HKD3_k127_4863158_63 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000003013 54.0
HKD3_k127_4863158_64 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00001151 53.0
HKD3_k127_4863158_7 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 4.354e-204 643.0
HKD3_k127_4863158_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 5.74e-199 624.0
HKD3_k127_4863158_9 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 2.33e-198 623.0
HKD3_k127_4869125_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1225.0
HKD3_k127_4869125_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.814e-245 769.0
HKD3_k127_4869125_10 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 308.0
HKD3_k127_4869125_11 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003547 249.0
HKD3_k127_4869125_12 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000006044 235.0
HKD3_k127_4869125_13 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000001611 229.0
HKD3_k127_4869125_14 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000469 225.0
HKD3_k127_4869125_15 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000009016 218.0
HKD3_k127_4869125_16 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000001027 213.0
HKD3_k127_4869125_19 helix_turn_helix, Lux Regulon K02282 - - 0.0000000000000000000000000000002089 128.0
HKD3_k127_4869125_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.609e-202 638.0
HKD3_k127_4869125_20 Domain of unknown function DUF302 - - - 0.000000000000000000000000000001295 127.0
HKD3_k127_4869125_21 Nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000001076 103.0
HKD3_k127_4869125_3 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 531.0
HKD3_k127_4869125_4 SMART alpha amylase catalytic sub domain K00705,K06044 - 2.4.1.25,5.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 504.0
HKD3_k127_4869125_5 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 452.0
HKD3_k127_4869125_6 HlyD family secretion protein K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 429.0
HKD3_k127_4869125_7 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 413.0
HKD3_k127_4869125_8 PFAM Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 394.0
HKD3_k127_4869125_9 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 383.0
HKD3_k127_4874233_0 GXGXG motif - - - 0.0 1309.0
HKD3_k127_4874233_1 Conserved region in glutamate synthase - - - 1.819e-306 943.0
HKD3_k127_4874233_10 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 591.0
HKD3_k127_4874233_11 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 574.0
HKD3_k127_4874233_12 Deoxyhypusine synthase K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 544.0
HKD3_k127_4874233_13 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 508.0
HKD3_k127_4874233_14 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 479.0
HKD3_k127_4874233_15 PFAM Peptidase S8 S53, subtilisin kexin sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 452.0
HKD3_k127_4874233_16 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 388.0
HKD3_k127_4874233_17 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 360.0
HKD3_k127_4874233_18 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 357.0
HKD3_k127_4874233_19 thiolester hydrolase activity K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004054 260.0
HKD3_k127_4874233_2 Glutamate synthase - - - 3.274e-264 822.0
HKD3_k127_4874233_20 ABC transporter, ATP-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000001154 228.0
HKD3_k127_4874233_21 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000007648 214.0
HKD3_k127_4874233_22 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000001956 202.0
HKD3_k127_4874233_23 ABC transporter, permease protein K02066 - - 0.0000000000000000000000000000000000000000000000000000003984 203.0
HKD3_k127_4874233_24 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000003628 198.0
HKD3_k127_4874233_25 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000006085 185.0
HKD3_k127_4874233_26 - - - - 0.00000000000000000000000000000000000000000000001386 180.0
HKD3_k127_4874233_27 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000003738 179.0
HKD3_k127_4874233_28 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000323 166.0
HKD3_k127_4874233_29 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000001417 164.0
HKD3_k127_4874233_3 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 2.336e-242 754.0
HKD3_k127_4874233_30 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000003456 168.0
HKD3_k127_4874233_31 - - - - 0.0000000000000000000000000000000000000001365 155.0
HKD3_k127_4874233_32 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000000002449 151.0
HKD3_k127_4874233_33 pyruvate K01571,K01958,K01960 - 4.1.1.3,6.4.1.1 0.0000000000000000000000000000000000004863 142.0
HKD3_k127_4874233_34 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000008323 145.0
HKD3_k127_4874233_35 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000001543 129.0
HKD3_k127_4874233_36 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000009187 126.0
HKD3_k127_4874233_37 MlaD protein K02067 - - 0.00000000000000000000000004887 119.0
HKD3_k127_4874233_38 Cysteine-rich secretory protein family - - - 0.0000000000000000000000404 106.0
HKD3_k127_4874233_39 protein N-acetylglucosaminyltransferase activity K09667 - 2.4.1.255 0.000000000000000225 90.0
HKD3_k127_4874233_4 two component, sigma54 specific, transcriptional regulator, Fis family K07713 - - 1.113e-216 679.0
HKD3_k127_4874233_40 transposase IS116 IS110 IS902 family protein K07486 - - 0.0000004408 51.0
HKD3_k127_4874233_41 EF-hand, calcium binding motif - - - 0.00001355 51.0
HKD3_k127_4874233_5 Biotin carboxylase C-terminal domain K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 5.749e-216 679.0
HKD3_k127_4874233_6 Ammonium Transporter K03320 - - 3.588e-211 661.0
HKD3_k127_4874233_7 Cro/C1-type HTH DNA-binding domain - - - 1.846e-203 640.0
HKD3_k127_4874233_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 3.182e-199 633.0
HKD3_k127_4874233_9 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 593.0
HKD3_k127_4909498_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 529.0
HKD3_k127_4909498_3 Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl- adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor K11996 GO:0000003,GO:0001403,GO:0001558,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006464,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0007114,GO:0008033,GO:0008150,GO:0008152,GO:0008641,GO:0009451,GO:0009987,GO:0010467,GO:0010570,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0016783,GO:0016874,GO:0016877,GO:0018117,GO:0018175,GO:0019538,GO:0019954,GO:0030447,GO:0032446,GO:0032447,GO:0032505,GO:0033554,GO:0034227,GO:0034470,GO:0034599,GO:0034641,GO:0034660,GO:0036211,GO:0036267,GO:0040007,GO:0040008,GO:0042221,GO:0042292,GO:0043170,GO:0043412,GO:0044182,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051301,GO:0051716,GO:0065007,GO:0070566,GO:0070647,GO:0070733,GO:0070783,GO:0070784,GO:0070887,GO:0071704,GO:0090304,GO:1900428,GO:1901360,GO:1901564,GO:2000220 2.7.7.80,2.8.1.11 0.000002323 57.0
HKD3_k127_4909501_0 ATPase domain of DNA mismatch repair MUTS family K07456 - - 1.404e-222 714.0
HKD3_k127_4909501_1 Thiamine-phosphate synthase K00941,K14153,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 489.0
HKD3_k127_4909501_10 Anti-sigma-28 factor, FlgM K02398 - - 0.000002617 53.0
HKD3_k127_4909501_2 Beta-eliminating lyase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 405.0
HKD3_k127_4909501_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 340.0
HKD3_k127_4909501_4 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 325.0
HKD3_k127_4909501_5 Acyl-transferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000002473 206.0
HKD3_k127_4909501_6 Yqey-like protein K09117 - - 0.000000000000000000000000000000000001285 143.0
HKD3_k127_4909501_7 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000001478 149.0
HKD3_k127_4909501_8 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000001763 109.0
HKD3_k127_4909519_0 7TM-HD extracellular K07037 - - 1.25e-244 782.0
HKD3_k127_4909519_1 SMART Elongator protein 3 MiaB NifB - - - 1.175e-241 751.0
HKD3_k127_4909519_10 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000003212 159.0
HKD3_k127_4909519_11 - - - - 0.0000000000000000000000000000000000000003891 151.0
HKD3_k127_4909519_12 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.0000000000000000000000000000000002418 140.0
HKD3_k127_4909519_13 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.000000000000000001925 92.0
HKD3_k127_4909519_14 dTDP-4-dehydrorhamnose 3,5-epimerase activity - - - 0.000008095 54.0
HKD3_k127_4909519_2 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 2.481e-195 615.0
HKD3_k127_4909519_3 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 465.0
HKD3_k127_4909519_4 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 432.0
HKD3_k127_4909519_5 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 402.0
HKD3_k127_4909519_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 349.0
HKD3_k127_4909519_7 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 334.0
HKD3_k127_4909519_8 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 317.0
HKD3_k127_4909519_9 PFAM asparagine synthase K06864 - - 0.00000000000000000000000000000000000000000000000000000002408 205.0
HKD3_k127_4973599_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase K14534 - 4.2.1.120,5.3.3.3 4.92e-268 831.0
HKD3_k127_4973599_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.493e-238 745.0
HKD3_k127_4973599_10 aspartate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 291.0
HKD3_k127_4973599_11 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 307.0
HKD3_k127_4973599_12 Histidine kinase K02668,K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001319 301.0
HKD3_k127_4973599_13 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000006868 216.0
HKD3_k127_4973599_14 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000004838 208.0
HKD3_k127_4973599_15 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000256 201.0
HKD3_k127_4973599_16 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000001798 201.0
HKD3_k127_4973599_17 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000009808 172.0
HKD3_k127_4973599_18 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000000000000000000001107 130.0
HKD3_k127_4973599_2 His Kinase A (phosphoacceptor) domain - - - 6.434e-215 678.0
HKD3_k127_4973599_3 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 492.0
HKD3_k127_4973599_4 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 482.0
HKD3_k127_4973599_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 437.0
HKD3_k127_4973599_6 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 423.0
HKD3_k127_4973599_7 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 401.0
HKD3_k127_4973599_8 Cytochrome c5530 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 388.0
HKD3_k127_4973599_9 signal-transduction protein with CBS domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 329.0
HKD3_k127_4983118_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 467.0
HKD3_k127_4983118_1 Branched-chain amino acid transport system / permease component K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 422.0
HKD3_k127_4983118_2 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 403.0
HKD3_k127_4983118_3 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002901 279.0
HKD3_k127_4983118_4 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007013 284.0
HKD3_k127_4983118_5 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000001277 244.0
HKD3_k127_4983118_6 HD domain - - - 0.000000000000000000000000000000000000000000000006563 182.0
HKD3_k127_4983118_7 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000005724 130.0
HKD3_k127_5006978_0 DEAD DEAH box helicase K06877 - - 0.0 1313.0
HKD3_k127_5006978_1 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1204.0
HKD3_k127_5006978_10 FecR protein - - - 0.00000000000000000000000000000001121 138.0
HKD3_k127_5006978_11 Protein of unknown function DUF86 - - - 0.000000000000000000000000004353 114.0
HKD3_k127_5006978_12 PFAM DNA polymerase, beta domain protein region K07075 - - 0.00000000000000000000000005867 109.0
HKD3_k127_5006978_13 Protein of unknown function (DUF2939) - - - 0.0000000000000000000000003736 112.0
HKD3_k127_5006978_14 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000008162 99.0
HKD3_k127_5006978_15 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000009136 91.0
HKD3_k127_5006978_16 - - - - 0.0000000000000007068 82.0
HKD3_k127_5006978_2 Belongs to the CarA family K01956 - 6.3.5.5 1.643e-205 643.0
HKD3_k127_5006978_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 489.0
HKD3_k127_5006978_4 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 442.0
HKD3_k127_5006978_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 424.0
HKD3_k127_5006978_7 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 305.0
HKD3_k127_5006978_8 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000005054 189.0
HKD3_k127_5006978_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000001134 181.0
HKD3_k127_5010013_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 1.395e-255 801.0
HKD3_k127_5010013_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 488.0
HKD3_k127_5010013_10 - - - - 0.0000000000000000000000000000007701 128.0
HKD3_k127_5010013_11 - - - - 0.000001603 56.0
HKD3_k127_5010013_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 471.0
HKD3_k127_5010013_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 367.0
HKD3_k127_5010013_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 327.0
HKD3_k127_5010013_5 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007961 308.0
HKD3_k127_5010013_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000001678 271.0
HKD3_k127_5010013_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002524 252.0
HKD3_k127_5010013_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000002773 208.0
HKD3_k127_5010013_9 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000001358 135.0
HKD3_k127_5030337_0 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 3.932e-231 720.0
HKD3_k127_5030337_1 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 597.0
HKD3_k127_504164_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.0 1134.0
HKD3_k127_504164_1 PFAM Pyruvate carboxyltransferase - - - 1.378e-317 979.0
HKD3_k127_504164_10 TIGRFAM methylmalonyl-CoA mutase C-terminal domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000132 217.0
HKD3_k127_504164_11 SpoIIAA-like - - - 0.000000000000000000000000000001186 124.0
HKD3_k127_504164_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.922e-283 881.0
HKD3_k127_504164_3 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.118e-283 876.0
HKD3_k127_504164_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 6.126e-222 696.0
HKD3_k127_504164_5 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 507.0
HKD3_k127_504164_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 427.0
HKD3_k127_504164_7 ErfK YbiS YcfS YnhG family protein K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 357.0
HKD3_k127_504164_8 Tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009905 345.0
HKD3_k127_504164_9 PFAM transposase IS116 IS110 IS902 family K07486 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004234 267.0
HKD3_k127_5081110_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 559.0
HKD3_k127_5081110_1 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 533.0
HKD3_k127_5081110_2 TIGRFAM MazG family protein K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 344.0
HKD3_k127_5081110_4 PFAM Colicin V production protein K03558 - - 0.000000000008288 73.0
HKD3_k127_5095468_0 Belongs to the ClpX chaperone family - - - 6.429e-246 772.0
HKD3_k127_5095468_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 2.695e-204 652.0
HKD3_k127_5095468_10 Formiminotransferase-cyclodeaminase - - - 0.0000000000000000000000005642 113.0
HKD3_k127_5095468_11 Cold shock K03704 - - 0.000000000000000000001002 96.0
HKD3_k127_5095468_12 NhaP-type Na H and K H - - - 0.00000000000000000001154 98.0
HKD3_k127_5095468_13 Protein of unknown function (DUF2892) - - - 0.000000000000000006146 85.0
HKD3_k127_5095468_2 PFAM Radical SAM K22226 - - 2.073e-195 615.0
HKD3_k127_5095468_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 567.0
HKD3_k127_5095468_4 PFAM histone deacetylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 426.0
HKD3_k127_5095468_5 PFAM dihydropteroate synthase, DHPS K15023 - 2.1.1.258 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 323.0
HKD3_k127_5095468_6 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008125 275.0
HKD3_k127_5095468_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000002728 241.0
HKD3_k127_5095468_8 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K21020 - 2.7.7.65 0.000000000000000000000000000000000000000003038 176.0
HKD3_k127_5095468_9 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000006284 155.0
HKD3_k127_5121535_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.563e-289 897.0
HKD3_k127_5121535_1 PFAM CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 493.0
HKD3_k127_5121535_2 AAA domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 348.0
HKD3_k127_5121535_3 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000003492 211.0
HKD3_k127_5121535_4 IMG reference gene - - - 0.000000000000000000000000000000000000000000000000000000003372 211.0
HKD3_k127_5147664_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K19594 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 377.0
HKD3_k127_5147664_1 cell adhesion involved in biofilm formation K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 366.0
HKD3_k127_5147664_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18903 - - 0.0000000000000000000000000000001005 128.0
HKD3_k127_5176162_0 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006662 394.0
HKD3_k127_5176162_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 301.0
HKD3_k127_5351783_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 2.143e-199 631.0
HKD3_k127_5351783_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 580.0
HKD3_k127_5351783_10 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000005908 199.0
HKD3_k127_5351783_11 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000004755 194.0
HKD3_k127_5351783_12 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000009722 177.0
HKD3_k127_5351783_13 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000000000000000000000000002249 159.0
HKD3_k127_5351783_14 - - - - 0.00000000004058 72.0
HKD3_k127_5351783_15 ISXO2-like transposase domain - - - 0.00000004283 54.0
HKD3_k127_5351783_2 PFAM Glycosyl transferase family 2 K10012,K20534 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 458.0
HKD3_k127_5351783_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 420.0
HKD3_k127_5351783_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 395.0
HKD3_k127_5351783_5 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 388.0
HKD3_k127_5351783_6 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 362.0
HKD3_k127_5351783_7 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 331.0
HKD3_k127_5351783_8 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009986 320.0
HKD3_k127_5351783_9 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 297.0
HKD3_k127_5368750_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.326e-320 987.0
HKD3_k127_5368750_1 Elongation factor Tu domain 2 K06207 - - 4.058e-309 956.0
HKD3_k127_5368750_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 5.757e-226 709.0
HKD3_k127_5368750_3 Transcriptional regulator - - - 0.0000000000000000000005198 100.0
HKD3_k127_5368750_4 Domain of unknown function (DUF4389) - - - 0.0000000000000000001091 93.0
HKD3_k127_5368750_6 Protein of unknown function (DUF3313) - - - 0.00000000000155 69.0
HKD3_k127_5368750_7 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD3_k127_5368750_8 Bacterial SH3 domain homologues - - - 0.0000001177 61.0
HKD3_k127_5412618_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0 1220.0
HKD3_k127_5412618_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.604e-262 833.0
HKD3_k127_5412618_10 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000006253 178.0
HKD3_k127_5412618_11 Ferritin-like domain - - - 0.0000000000000000001184 95.0
HKD3_k127_5412618_12 - - - - 0.000001063 55.0
HKD3_k127_5412618_2 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 3.776e-198 629.0
HKD3_k127_5412618_3 Fe-S center protein K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 597.0
HKD3_k127_5412618_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 586.0
HKD3_k127_5412618_5 PFAM Radical SAM K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 491.0
HKD3_k127_5412618_6 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 463.0
HKD3_k127_5412618_7 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003097 282.0
HKD3_k127_5412618_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000001114 203.0
HKD3_k127_5412618_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000002746 194.0
HKD3_k127_5430365_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 479.0
HKD3_k127_5430365_1 Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK) K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 334.0
HKD3_k127_5430365_2 PFAM Type II secretion system protein E K02283,K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001593 265.0
HKD3_k127_5430365_3 Type II secretion system (T2SS), protein F K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001584 256.0
HKD3_k127_5430365_4 PFAM type II secretion system K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
HKD3_k127_5430365_5 COG4448 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
HKD3_k127_549652_0 Peptidase family U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 537.0
HKD3_k127_549652_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 491.0
HKD3_k127_549652_2 ligase activity K05844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008683 253.0
HKD3_k127_549652_3 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000002253 223.0
HKD3_k127_549652_4 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.00000000000000000000000000000000000000000000000000000000002687 213.0
HKD3_k127_549652_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.000000000000001355 80.0
HKD3_k127_570805_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.857e-301 938.0
HKD3_k127_570805_1 Thiamine pyrophosphate enzyme, central K01652 - 2.2.1.6 1.414e-288 894.0
HKD3_k127_570805_10 Methionyl-tRNA formyltransferase K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 432.0
HKD3_k127_570805_11 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 416.0
HKD3_k127_570805_12 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 332.0
HKD3_k127_570805_13 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 330.0
HKD3_k127_570805_14 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 288.0
HKD3_k127_570805_15 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003038 280.0
HKD3_k127_570805_16 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000005252 251.0
HKD3_k127_570805_17 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000002752 236.0
HKD3_k127_570805_18 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000002029 216.0
HKD3_k127_570805_19 - - - - 0.000000000000000000000000000000000000000000000009779 181.0
HKD3_k127_570805_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.043e-248 776.0
HKD3_k127_570805_20 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000001227 176.0
HKD3_k127_570805_21 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.000000000000000000000000000000000000000000001442 169.0
HKD3_k127_570805_22 - - - - 0.0000000000000000000000000000000000000000001469 174.0
HKD3_k127_570805_23 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000001147 151.0
HKD3_k127_570805_25 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000000000001428 126.0
HKD3_k127_570805_26 - - - - 0.0000000000000000000000000000002677 133.0
HKD3_k127_570805_27 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000000002471 119.0
HKD3_k127_570805_29 heat shock protein binding - - - 0.000000000000000004971 87.0
HKD3_k127_570805_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.514e-199 627.0
HKD3_k127_570805_30 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000009512 78.0
HKD3_k127_570805_31 Protein of unknown function DUF86 - - - 0.00000000001838 64.0
HKD3_k127_570805_32 Protein of unknown function DUF86 K07075 - - 0.0000000005847 61.0
HKD3_k127_570805_33 - - - - 0.000000059 61.0
HKD3_k127_570805_34 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000002353 59.0
HKD3_k127_570805_35 Transposase is116 is110 is902 family K07486 - - 0.000001216 50.0
HKD3_k127_570805_4 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 613.0
HKD3_k127_570805_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 603.0
HKD3_k127_570805_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 562.0
HKD3_k127_570805_7 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 513.0
HKD3_k127_570805_8 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 438.0
HKD3_k127_570805_9 PFAM Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 443.0
HKD3_k127_5727545_0 Large extracellular alpha-helical protein K06894 - - 0.0 1105.0
HKD3_k127_5727545_1 penicillin binding K05367 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 621.0
HKD3_k127_5727545_10 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000005504 82.0
HKD3_k127_5727545_11 addiction module killer protein - - - 0.000002998 49.0
HKD3_k127_5727545_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 488.0
HKD3_k127_5727545_3 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 432.0
HKD3_k127_5727545_4 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 388.0
HKD3_k127_5727545_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001294 268.0
HKD3_k127_5727545_6 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000002587 231.0
HKD3_k127_5727545_7 Transcriptional regulator - - - 0.00000000000000000000000000000000005762 136.0
HKD3_k127_5727545_8 - - - - 0.000000000000000000000000000000004676 135.0
HKD3_k127_5727545_9 addiction module killer protein - - - 0.0000000000000000000000012 104.0
HKD3_k127_5770303_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 566.0
HKD3_k127_5770303_1 membrane K08978,K12962 - - 0.0000000000000004481 78.0
HKD3_k127_5770303_2 Lytic transglycosylase catalytic K08307 - - 0.000000000001784 69.0
HKD3_k127_5857721_0 reductase alpha subunit K00394 - 1.8.99.2 0.0 1279.0
HKD3_k127_5857721_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1109.0
HKD3_k127_5857721_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001921 283.0
HKD3_k127_5857721_11 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000904 280.0
HKD3_k127_5857721_12 Nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000008579 234.0
HKD3_k127_5857721_13 Sulfate ABC transporter periplasmic sulfate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000004636 222.0
HKD3_k127_5857721_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004014 210.0
HKD3_k127_5857721_15 PFAM magnesium chelatase K07391 - - 0.00000000000000000000000000000000000000000000000000000001578 200.0
HKD3_k127_5857721_16 NAD+ diphosphatase activity K01515,K03426 - 3.6.1.13,3.6.1.22 0.00000000000000000000000000000000000000000000000000000004337 205.0
HKD3_k127_5857721_17 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000002442 185.0
HKD3_k127_5857721_18 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000004244 163.0
HKD3_k127_5857721_19 - - - - 0.000000000000000000000000000000006082 131.0
HKD3_k127_5857721_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1032.0
HKD3_k127_5857721_20 - - - - 0.0000000000000000000000000009785 116.0
HKD3_k127_5857721_21 Sh3 type 3 domain protein K03642,K07184 - - 0.00000000000000000001068 101.0
HKD3_k127_5857721_3 FAD dependent oxidoreductase K16885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 602.0
HKD3_k127_5857721_4 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 581.0
HKD3_k127_5857721_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 467.0
HKD3_k127_5857721_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 458.0
HKD3_k127_5857721_7 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 426.0
HKD3_k127_5857721_8 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 335.0
HKD3_k127_5857721_9 reductase, beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 283.0
HKD3_k127_5874387_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 6.776e-285 895.0
HKD3_k127_5874387_1 Carboxyl transferase domain K01969,K13778 - 6.4.1.4,6.4.1.5 5.668e-278 861.0
HKD3_k127_5874387_10 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 553.0
HKD3_k127_5874387_11 Short chain fatty acid transporter K02106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000693 551.0
HKD3_k127_5874387_12 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 431.0
HKD3_k127_5874387_13 Belongs to the amidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 428.0
HKD3_k127_5874387_14 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 418.0
HKD3_k127_5874387_15 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 398.0
HKD3_k127_5874387_16 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 387.0
HKD3_k127_5874387_17 enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 382.0
HKD3_k127_5874387_18 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 361.0
HKD3_k127_5874387_19 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 332.0
HKD3_k127_5874387_2 4Fe-4S ferredoxin iron-sulfur binding - - - 5.884e-243 766.0
HKD3_k127_5874387_20 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 304.0
HKD3_k127_5874387_21 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000001335 214.0
HKD3_k127_5874387_22 dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000000000000001938 216.0
HKD3_k127_5874387_23 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000001367 217.0
HKD3_k127_5874387_24 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000002327 214.0
HKD3_k127_5874387_25 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000004968 176.0
HKD3_k127_5874387_26 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000008236 154.0
HKD3_k127_5874387_27 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000004933 129.0
HKD3_k127_5874387_28 PFAM DsrE family protein - - - 0.000000000000000001362 88.0
HKD3_k127_5874387_29 - - - - 0.000000000000001227 83.0
HKD3_k127_5874387_3 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 6.864e-229 712.0
HKD3_k127_5874387_30 Rhodanese-related sulfurtransferase - - - 0.000006057 49.0
HKD3_k127_5874387_31 Sulfur carrier protein TusA K04085 - - 0.00006198 49.0
HKD3_k127_5874387_4 L-carnitine dehydratase bile acid-inducible protein F - - - 1.302e-218 685.0
HKD3_k127_5874387_5 acyl-CoA transferases carnitine dehydratase - - - 1.349e-213 671.0
HKD3_k127_5874387_6 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 621.0
HKD3_k127_5874387_7 HMGL-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 582.0
HKD3_k127_5874387_8 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 589.0
HKD3_k127_5874387_9 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 565.0
HKD3_k127_6083632_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.459e-196 618.0
HKD3_k127_6083632_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 311.0
HKD3_k127_6083632_2 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000000000000000000000000004035 133.0
HKD3_k127_6083632_3 Right handed beta helix region - - - 0.0000000000000000000000002632 117.0
HKD3_k127_6083632_4 Permease MlaE K02066 - - 0.00000000000000000001541 93.0
HKD3_k127_6083632_5 Right handed beta helix region - - - 0.00000000000000000007817 100.0
HKD3_k127_6098967_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0 1157.0
HKD3_k127_6098967_1 PFAM Cytochrome C K04561 - 1.7.2.5 0.0 1114.0
HKD3_k127_6098967_10 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 433.0
HKD3_k127_6098967_11 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 381.0
HKD3_k127_6098967_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 375.0
HKD3_k127_6098967_13 Mammalian cell entry related domain protein K02067,K06192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 316.0
HKD3_k127_6098967_14 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 315.0
HKD3_k127_6098967_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000294 258.0
HKD3_k127_6098967_16 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009135 247.0
HKD3_k127_6098967_17 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000004616 216.0
HKD3_k127_6098967_18 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000004129 211.0
HKD3_k127_6098967_19 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000001131 198.0
HKD3_k127_6098967_2 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 7.908e-272 859.0
HKD3_k127_6098967_20 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000000000000000136 186.0
HKD3_k127_6098967_21 phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000001813 189.0
HKD3_k127_6098967_22 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000001256 164.0
HKD3_k127_6098967_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000002586 141.0
HKD3_k127_6098967_24 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000000000000000000000000851 146.0
HKD3_k127_6098967_25 ABC-type transport auxiliary lipoprotein component K18480 - - 0.0000000000000000000000001856 113.0
HKD3_k127_6098967_26 COGs COG0767 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000006144 69.0
HKD3_k127_6098967_3 PFAM Transketolase K00615 - 2.2.1.1 2.133e-218 689.0
HKD3_k127_6098967_4 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 601.0
HKD3_k127_6098967_5 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 553.0
HKD3_k127_6098967_6 alcohol dehydrogenase K00001,K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 485.0
HKD3_k127_6098967_7 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 475.0
HKD3_k127_6098967_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 458.0
HKD3_k127_6098967_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 439.0
HKD3_k127_6122085_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.424e-248 780.0
HKD3_k127_6122085_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.13e-246 768.0
HKD3_k127_6122085_2 Mut7-C ubiquitin - - - 0.00000000000002105 76.0
HKD3_k127_6129198_0 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.0 1157.0
HKD3_k127_6129198_1 Endoribonuclease that initiates mRNA decay K18682 - - 1.309e-235 741.0
HKD3_k127_6129198_10 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 382.0
HKD3_k127_6129198_11 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 357.0
HKD3_k127_6129198_12 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 326.0
HKD3_k127_6129198_13 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 321.0
HKD3_k127_6129198_14 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 311.0
HKD3_k127_6129198_15 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004488 282.0
HKD3_k127_6129198_16 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004157 254.0
HKD3_k127_6129198_17 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000002032 246.0
HKD3_k127_6129198_19 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000001774 215.0
HKD3_k127_6129198_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 3.261e-194 614.0
HKD3_k127_6129198_20 - - - - 0.00000000000000000000000000000000000000000000000000000008125 203.0
HKD3_k127_6129198_21 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000001028 169.0
HKD3_k127_6129198_22 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000001071 142.0
HKD3_k127_6129198_24 Tautomerase enzyme - - - 0.0000000000000000000000003907 106.0
HKD3_k127_6129198_25 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000000473 105.0
HKD3_k127_6129198_26 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000000000000000000000002871 102.0
HKD3_k127_6129198_27 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000001037 68.0
HKD3_k127_6129198_28 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000039 66.0
HKD3_k127_6129198_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
HKD3_k127_6129198_30 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000666 66.0
HKD3_k127_6129198_31 Serine aminopeptidase, S33 - - - 0.0001157 51.0
HKD3_k127_6129198_32 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000131 49.0
HKD3_k127_6129198_33 Histidine kinase-like ATPase domain - - - 0.0005536 46.0
HKD3_k127_6129198_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 447.0
HKD3_k127_6129198_5 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 415.0
HKD3_k127_6129198_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
HKD3_k127_6129198_7 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 415.0
HKD3_k127_6129198_8 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 402.0
HKD3_k127_6129198_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 398.0
HKD3_k127_6135863_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 573.0
HKD3_k127_6135863_1 nucleic acid binding K03698 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 374.0
HKD3_k127_6135863_2 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 385.0
HKD3_k127_6135863_3 CHASE3 domain - - - 0.000000000000000000000000000000000000000000000000000000000002388 241.0
HKD3_k127_6135863_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000001737 211.0
HKD3_k127_6135863_5 Universal stress protein family - - - 0.00000000000000000000000000000000000000001049 159.0
HKD3_k127_6135863_6 Protein of unknown function (DUF2283) - - - 0.000000000000000000000000000001471 122.0
HKD3_k127_6135863_7 - - - - 0.00000000000000000000005491 105.0
HKD3_k127_6169235_0 peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008023 467.0
HKD3_k127_6169235_1 cluster binding protein K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 470.0
HKD3_k127_6169235_2 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 462.0
HKD3_k127_6169235_3 Polysaccharide deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000002697 169.0
HKD3_k127_6169235_4 - - - - 0.0000000000000000000000000001056 125.0
HKD3_k127_6169235_5 protein trimerization - - - 0.0000000000000000000002959 100.0
HKD3_k127_6195219_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0 1049.0
HKD3_k127_6195219_1 Belongs to the helicase family. UvrD subfamily - - - 1.091e-292 934.0
HKD3_k127_6195219_10 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000004859 217.0
HKD3_k127_6195219_11 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000001547 173.0
HKD3_k127_6195219_12 Domain of unknown function (DUF5122) beta-propeller - - - 0.000000000000000000000000000000000001808 154.0
HKD3_k127_6195219_13 cellular response to heat K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000222 144.0
HKD3_k127_6195219_14 - - - - 0.000000000000000000000000000000001299 143.0
HKD3_k127_6195219_15 - - - - 0.000000000000000000000000000004425 128.0
HKD3_k127_6195219_16 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000009757 121.0
HKD3_k127_6195219_17 Nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000006725 114.0
HKD3_k127_6195219_18 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000007591 74.0
HKD3_k127_6195219_2 SMART Elongator protein 3 MiaB NifB - - - 1.591e-260 816.0
HKD3_k127_6195219_3 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 8.906e-230 728.0
HKD3_k127_6195219_4 ATP-dependent nuclease subunit B-like - - - 1.454e-227 734.0
HKD3_k127_6195219_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 3.93e-212 681.0
HKD3_k127_6195219_6 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 557.0
HKD3_k127_6195219_7 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 454.0
HKD3_k127_6195219_8 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 441.0
HKD3_k127_6195219_9 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 291.0
HKD3_k127_6233989_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 2.153e-287 908.0
HKD3_k127_6233989_1 aconitate hydratase K01681 - 4.2.1.3 1.502e-280 876.0
HKD3_k127_6233989_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000706 535.0
HKD3_k127_6233989_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 295.0
HKD3_k127_6233989_4 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000002939 233.0
HKD3_k127_6233989_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000002279 169.0
HKD3_k127_6233989_6 transcription regulator activity K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000008674 144.0
HKD3_k127_6233989_7 membrane K08978 - - 0.00000000000000000000000002188 113.0
HKD3_k127_6233989_8 cell division K03586 GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0019954,GO:0022402,GO:0022414,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0043093,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0071944 - 0.00000000009358 66.0
HKD3_k127_631199_0 peptidyl-tyrosine sulfation - - - 9.605e-308 990.0
HKD3_k127_631199_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 552.0
HKD3_k127_631199_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000005326 223.0
HKD3_k127_631199_11 PFAM Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000003132 147.0
HKD3_k127_631199_12 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000004583 143.0
HKD3_k127_631199_14 - - - - 0.0000000000002345 81.0
HKD3_k127_631199_15 - - - - 0.000000000006502 72.0
HKD3_k127_631199_2 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 477.0
HKD3_k127_631199_3 SMART PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 363.0
HKD3_k127_631199_4 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 326.0
HKD3_k127_631199_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 327.0
HKD3_k127_631199_6 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 314.0
HKD3_k127_631199_7 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 286.0
HKD3_k127_631199_8 PFAM Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005942 280.0
HKD3_k127_631199_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 258.0
HKD3_k127_6426015_0 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1182.0
HKD3_k127_6426015_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005627 335.0
HKD3_k127_6426015_2 abc transporter atp-binding protein K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003918 273.0
HKD3_k127_6426015_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007229 231.0
HKD3_k127_6426015_4 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000006959 179.0
HKD3_k127_6481518_0 Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain K01945 - 6.3.4.13 4.646e-244 762.0
HKD3_k127_6481518_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 550.0
HKD3_k127_6481518_10 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000001844 214.0
HKD3_k127_6481518_11 THIoesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000000000000000008982 213.0
HKD3_k127_6481518_12 4Fe-4S dicluster domain K00196 - - 0.000000000000000000000000000000000000000000000000000000000004124 214.0
HKD3_k127_6481518_14 - - - - 0.000000000000000000000000000000000000001524 152.0
HKD3_k127_6481518_15 - - - - 0.00000000002054 70.0
HKD3_k127_6481518_16 Transposase is116 is110 is902 family K07486 - - 0.000001216 50.0
HKD3_k127_6481518_17 cheY-homologous receiver domain - - - 0.0000872 51.0
HKD3_k127_6481518_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007573 464.0
HKD3_k127_6481518_3 phosphorelay sensor kinase activity K07708,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 406.0
HKD3_k127_6481518_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008062 377.0
HKD3_k127_6481518_5 CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 357.0
HKD3_k127_6481518_6 MGS-like domain K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002258 275.0
HKD3_k127_6481518_7 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001401 258.0
HKD3_k127_6481518_8 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000001407 240.0
HKD3_k127_6481518_9 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000004731 241.0
HKD3_k127_6538098_0 FAD binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1265.0
HKD3_k127_6538098_1 PFAM nickel-dependent hydrogenase, large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 2.562e-218 687.0
HKD3_k127_6538098_2 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009174 476.0
HKD3_k127_6538098_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 462.0
HKD3_k127_6538098_4 cell adhesion involved in biofilm formation K02014 - - 0.00000000000000000000000000000000000007731 147.0
HKD3_k127_6538098_5 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000001711 126.0
HKD3_k127_6538098_6 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000006362 105.0
HKD3_k127_6538098_7 FAD dependent oxidoreductase - - - 0.0000000000000000000004936 101.0
HKD3_k127_6538098_8 TIGRFAM DNA binding domain, excisionase family K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000005917 66.0
HKD3_k127_6689324_0 Acetyl xylan esterase (AXE1) - - - 3.5e-286 891.0
HKD3_k127_6689324_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.21e-239 775.0
HKD3_k127_6689324_10 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 469.0
HKD3_k127_6689324_11 cysteine synthase A K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 449.0
HKD3_k127_6689324_12 PFAM Glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 449.0
HKD3_k127_6689324_13 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
HKD3_k127_6689324_14 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 343.0
HKD3_k127_6689324_15 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 338.0
HKD3_k127_6689324_16 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 300.0
HKD3_k127_6689324_17 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000002592 251.0
HKD3_k127_6689324_18 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003779 240.0
HKD3_k127_6689324_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000044 220.0
HKD3_k127_6689324_2 Pfam:DUF490 K09800 - - 1.352e-215 713.0
HKD3_k127_6689324_20 PIN domain - - - 0.00000000000000000000000000000000000000001381 156.0
HKD3_k127_6689324_21 DNA polymerase beta domain protein region K07075 - - 0.00000000000000000000000000000000007939 137.0
HKD3_k127_6689324_22 Stress responsive alpha-beta barrel - - - 0.00000000000000000000000002716 110.0
HKD3_k127_6689324_23 SpoVT / AbrB like domain - - - 0.000000000000000000000439 97.0
HKD3_k127_6689324_24 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000007851 95.0
HKD3_k127_6689324_25 Protein of unknown function DUF86 - - - 0.000000000000000003679 86.0
HKD3_k127_6689324_27 Rhodanese-like domain K01069 - 3.1.2.6 0.000000002332 64.0
HKD3_k127_6689324_28 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD3_k127_6689324_3 Belongs to the glycosyl hydrolase 57 family K03406,K16149 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 2.904e-207 659.0
HKD3_k127_6689324_4 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 2.054e-199 627.0
HKD3_k127_6689324_5 CoA binding domain K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 623.0
HKD3_k127_6689324_6 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 564.0
HKD3_k127_6689324_7 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 514.0
HKD3_k127_6689324_8 Sulfotransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 497.0
HKD3_k127_6689324_9 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009464 481.0
HKD3_k127_6734888_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1812.0
HKD3_k127_6734888_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1037.0
HKD3_k127_6734888_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000227 228.0
HKD3_k127_6734888_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000012 227.0
HKD3_k127_6734888_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000005585 83.0
HKD3_k127_6798452_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 596.0
HKD3_k127_6798452_1 Reductase C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 583.0
HKD3_k127_6798452_2 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008084 391.0
HKD3_k127_6798452_3 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000000001383 149.0
HKD3_k127_6798452_4 Protein of unknown function (DUF3124) - - - 0.00000000000000001883 89.0
HKD3_k127_6798452_5 ISXO2-like transposase domain - - - 0.000000003721 57.0
HKD3_k127_7255944_0 Beta-lactamase - - - 0.0 1022.0
HKD3_k127_7255944_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.367e-232 731.0
HKD3_k127_7255944_10 PFAM Plasmid stabilisation system K06218 - - 0.000000000000000000008151 95.0
HKD3_k127_7255944_11 - - - - 0.0000000000000001071 81.0
HKD3_k127_7255944_12 - - - - 0.000000000002353 69.0
HKD3_k127_7255944_13 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000005139 57.0
HKD3_k127_7255944_14 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0002962 43.0
HKD3_k127_7255944_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 7.498e-213 674.0
HKD3_k127_7255944_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 599.0
HKD3_k127_7255944_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 480.0
HKD3_k127_7255944_5 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K15893 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 431.0
HKD3_k127_7255944_6 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000003578 239.0
HKD3_k127_7255944_7 - - - - 0.000000000000000000000000000000001698 130.0
HKD3_k127_7255944_8 - - - - 0.00000000000000000000000000001647 138.0
HKD3_k127_7255944_9 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.0000000000000000000000000004335 114.0
HKD3_k127_7270260_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 311.0
HKD3_k127_7270260_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008158 238.0
HKD3_k127_7270260_2 - - - - 0.0000000000000000007781 86.0
HKD3_k127_7291474_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07789,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 523.0
HKD3_k127_7291474_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 478.0
HKD3_k127_7291474_2 cell adhesion involved in biofilm formation K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 371.0
HKD3_k127_7301011_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1563.0
HKD3_k127_7301011_1 MacB-like periplasmic core domain K02004 - - 0.0 1052.0
HKD3_k127_7301011_10 radical SAM domain protein K03716 - 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 405.0
HKD3_k127_7301011_11 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 342.0
HKD3_k127_7301011_12 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 335.0
HKD3_k127_7301011_13 PFAM Glycosyl hydrolases family 8 K20542 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 332.0
HKD3_k127_7301011_14 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 312.0
HKD3_k127_7301011_15 RNA polymerase sigma factor K02405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 302.0
HKD3_k127_7301011_16 NUBPL iron-transfer P-loop NTPase K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 301.0
HKD3_k127_7301011_17 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 296.0
HKD3_k127_7301011_18 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000000000000000000000795 233.0
HKD3_k127_7301011_19 Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000001937 231.0
HKD3_k127_7301011_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.65e-301 934.0
HKD3_k127_7301011_20 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000001127 205.0
HKD3_k127_7301011_21 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000004192 190.0
HKD3_k127_7301011_22 PFAM UBA THIF-type NAD FAD binding - - - 0.000000000000000000000000000000000000000000000000346 186.0
HKD3_k127_7301011_23 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000005517 174.0
HKD3_k127_7301011_24 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000004004 169.0
HKD3_k127_7301011_25 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000172 152.0
HKD3_k127_7301011_26 membrane K08978,K12962 - - 0.000000000000000000000000000000000000001444 150.0
HKD3_k127_7301011_27 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000000008704 147.0
HKD3_k127_7301011_28 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.00000000000000000000000000000000000001523 145.0
HKD3_k127_7301011_29 Protein of unknown function (DUF3568) - - - 0.000000000000000000000000000006465 124.0
HKD3_k127_7301011_3 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.552e-230 726.0
HKD3_k127_7301011_30 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000001785 112.0
HKD3_k127_7301011_31 lipolytic protein G-D-S-L family K20306 - - 0.000000000000000000000006215 115.0
HKD3_k127_7301011_32 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K22491 - - 0.0000000000000000000006546 100.0
HKD3_k127_7301011_33 - - - - 0.00000000000000000002746 96.0
HKD3_k127_7301011_34 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000009756 84.0
HKD3_k127_7301011_35 - - - - 0.000000000002571 70.0
HKD3_k127_7301011_36 GDSL-like Lipase/Acylhydrolase - - - 0.00000000002167 76.0
HKD3_k127_7301011_37 PFAM YcfA-like protein - - - 0.0000000007844 62.0
HKD3_k127_7301011_38 ISXO2-like transposase domain - - - 0.0000000239 55.0
HKD3_k127_7301011_39 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000002829 53.0
HKD3_k127_7301011_4 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 4.088e-222 704.0
HKD3_k127_7301011_40 PFAM YcfA-like protein - - - 0.000005307 51.0
HKD3_k127_7301011_5 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 6.712e-217 687.0
HKD3_k127_7301011_6 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 581.0
HKD3_k127_7301011_7 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 473.0
HKD3_k127_7301011_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005463 467.0
HKD3_k127_7301011_9 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
HKD3_k127_7325778_0 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 580.0
HKD3_k127_7325778_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 375.0
HKD3_k127_7325778_2 Cupin domain - - - 0.0000000000000000000000000000000000000000000003247 169.0
HKD3_k127_7325778_3 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000002319 149.0
HKD3_k127_7325778_4 - - - - 0.00000000000000000000000000000159 130.0
HKD3_k127_7408689_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 5.416e-263 827.0
HKD3_k127_7408689_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 608.0
HKD3_k127_7408689_10 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 476.0
HKD3_k127_7408689_11 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 438.0
HKD3_k127_7408689_12 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 419.0
HKD3_k127_7408689_13 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 398.0
HKD3_k127_7408689_14 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 402.0
HKD3_k127_7408689_15 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 390.0
HKD3_k127_7408689_16 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 393.0
HKD3_k127_7408689_17 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 317.0
HKD3_k127_7408689_18 PFAM ApbE family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 299.0
HKD3_k127_7408689_19 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 300.0
HKD3_k127_7408689_2 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 602.0
HKD3_k127_7408689_20 Sulfite exporter TauE/SafE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001768 279.0
HKD3_k127_7408689_21 PFAM CBS domain K04767 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004369 275.0
HKD3_k127_7408689_22 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001427 273.0
HKD3_k127_7408689_23 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000003106 252.0
HKD3_k127_7408689_24 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000055 237.0
HKD3_k127_7408689_25 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.000000000000000000000000000000000000000000007553 180.0
HKD3_k127_7408689_26 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000735 167.0
HKD3_k127_7408689_27 protein conserved in bacteria (DUF2062) K09928 - - 0.00000000000000000000000000000000000002105 149.0
HKD3_k127_7408689_28 YacP-like NYN domain K06962 - - 0.000000000000000000000000000000000008 141.0
HKD3_k127_7408689_29 - - - - 0.000000000000000000000000000000009565 130.0
HKD3_k127_7408689_3 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 589.0
HKD3_k127_7408689_30 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.00000000000000000000000000007381 120.0
HKD3_k127_7408689_31 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000002191 123.0
HKD3_k127_7408689_32 Hypothetical methyltransferase - - - 0.00000000000000000000000008203 115.0
HKD3_k127_7408689_33 tetratricopeptide repeat - - - 0.00000000000000008021 90.0
HKD3_k127_7408689_34 PFAM Heavy metal transport detoxification protein - - - 0.00000000000001811 75.0
HKD3_k127_7408689_35 - - - - 0.00000000004264 67.0
HKD3_k127_7408689_36 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000002533 72.0
HKD3_k127_7408689_37 - - - - 0.0000009684 56.0
HKD3_k127_7408689_38 VanZ like family - - - 0.00001821 53.0
HKD3_k127_7408689_39 Domain of unknown function (DUF1772) - - - 0.00004061 51.0
HKD3_k127_7408689_4 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 579.0
HKD3_k127_7408689_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 574.0
HKD3_k127_7408689_6 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 561.0
HKD3_k127_7408689_7 PFAM glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 542.0
HKD3_k127_7408689_8 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 546.0
HKD3_k127_7408689_9 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 494.0
HKD3_k127_7421950_0 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0 1050.0
HKD3_k127_7421950_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.793e-301 935.0
HKD3_k127_7421950_10 Domain of unknown function (DUF4346) K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 377.0
HKD3_k127_7421950_11 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 369.0
HKD3_k127_7421950_12 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 326.0
HKD3_k127_7421950_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 306.0
HKD3_k127_7421950_14 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004759 272.0
HKD3_k127_7421950_15 DisA bacterial checkpoint controller nucleotide-binding K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007048 272.0
HKD3_k127_7421950_16 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002549 267.0
HKD3_k127_7421950_17 Domain of unknown function (DUF4881) - - - 0.000000000000000000000000000000000000000000000000000000000000000000393 235.0
HKD3_k127_7421950_18 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000434 181.0
HKD3_k127_7421950_19 - - - - 0.000000000000000000000000000000000000000000001058 177.0
HKD3_k127_7421950_2 Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 8.945e-280 884.0
HKD3_k127_7421950_20 Universal stress protein - - - 0.000000000000000000000000000000000000000000007397 166.0
HKD3_k127_7421950_21 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000189 150.0
HKD3_k127_7421950_22 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000001048 144.0
HKD3_k127_7421950_23 HNH nucleases - - - 0.000000000000000000000000000000000000252 141.0
HKD3_k127_7421950_24 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000001543 140.0
HKD3_k127_7421950_25 - - - - 0.0000000000000000000000000000006039 125.0
HKD3_k127_7421950_26 PFAM response regulator receiver - - - 0.000000000000000000000000000003886 125.0
HKD3_k127_7421950_27 YHS domain - - - 0.0000000000000000000006194 97.0
HKD3_k127_7421950_28 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000007678 101.0
HKD3_k127_7421950_29 PFAM YbbR family protein - - - 0.000000000000001639 87.0
HKD3_k127_7421950_3 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 1.222e-208 657.0
HKD3_k127_7421950_31 - - - - 0.000003566 55.0
HKD3_k127_7421950_4 Integral membrane sensor signal transduction histidine kinase K02482 - 2.7.13.3 3.286e-208 661.0
HKD3_k127_7421950_5 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07712 - - 4.494e-200 637.0
HKD3_k127_7421950_6 Phosphoglucose isomerase K01810,K13810 - 2.2.1.2,5.3.1.9 2.158e-198 629.0
HKD3_k127_7421950_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 586.0
HKD3_k127_7421950_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 534.0
HKD3_k127_7421950_9 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 526.0
HKD3_k127_7454284_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1592.0
HKD3_k127_7454284_1 PFAM magnesium chelatase K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 544.0
HKD3_k127_745575_0 BadF BadG BcrA BcrD - - - 0.0 2014.0
HKD3_k127_745575_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 2.482e-310 960.0
HKD3_k127_745575_10 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003505 277.0
HKD3_k127_745575_11 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000001835 229.0
HKD3_k127_745575_12 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000005124 222.0
HKD3_k127_745575_13 integral membrane protein - - - 0.0000000000000000000000000000000000000000000002232 176.0
HKD3_k127_745575_14 transcriptional regulator - - - 0.0000000000000000000000000000000000000000004121 164.0
HKD3_k127_745575_16 Right handed beta helix region - - - 0.000000000000000000000000000002447 132.0
HKD3_k127_745575_17 cell redox homeostasis K03671 - - 0.000000000000000000000000000002953 125.0
HKD3_k127_745575_19 Right handed beta helix region - - - 0.0000000000000000006872 98.0
HKD3_k127_745575_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.531e-309 960.0
HKD3_k127_745575_20 Right handed beta helix region - - - 0.0000000000000000009753 95.0
HKD3_k127_745575_23 integral membrane protein - - - 0.0000000000000004263 88.0
HKD3_k127_745575_24 - - - - 0.0000000000000006816 78.0
HKD3_k127_745575_25 Right handed beta helix region - - - 0.0000000000001821 81.0
HKD3_k127_745575_27 - - - - 0.000004944 54.0
HKD3_k127_745575_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 3.324e-274 850.0
HKD3_k127_745575_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 527.0
HKD3_k127_745575_5 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 323.0
HKD3_k127_745575_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 316.0
HKD3_k127_745575_7 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 312.0
HKD3_k127_745575_8 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 284.0
HKD3_k127_745575_9 molybdopterin oxidoreductase Fe4S4 region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006112 274.0
HKD3_k127_7462524_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 2.25e-318 1005.0
HKD3_k127_7462524_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 1.625e-312 971.0
HKD3_k127_7462524_10 PFAM Major Facilitator Superfamily - - - 0.000001446 53.0
HKD3_k127_7462524_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 584.0
HKD3_k127_7462524_3 Efflux transporter, RND family, MFP subunit K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009155 505.0
HKD3_k127_7462524_4 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 437.0
HKD3_k127_7462524_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004925 257.0
HKD3_k127_7462524_7 Diguanylate cyclase K21084 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000001157 228.0
HKD3_k127_7462524_8 Transcriptional regulator, marR - - - 0.00000000000000000000000000000002846 130.0
HKD3_k127_7462524_9 Belongs to the pirin family K06911 - - 0.0000000000000000000002508 97.0
HKD3_k127_7484185_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 347.0
HKD3_k127_7484185_1 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 284.0
HKD3_k127_7484185_2 IMG reference gene - - - 0.00000000000000000000000000000000000000000000000000000000002823 213.0
HKD3_k127_7484185_4 Tetratricopeptide TPR_2 repeat protein - - - 0.00003641 51.0
HKD3_k127_7498559_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1046.0
HKD3_k127_7498559_1 PFAM Transposase, Mutator family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 424.0
HKD3_k127_7498559_2 COG4448 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 349.0
HKD3_k127_7498559_3 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002042 271.0
HKD3_k127_7498559_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000001864 121.0
HKD3_k127_7498559_5 - - - - 0.000000000000000004791 88.0
HKD3_k127_7529054_0 membrane protein involved in D-alanine export K19294 - - 4.141e-210 665.0
HKD3_k127_7529054_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 497.0
HKD3_k127_7529054_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 482.0
HKD3_k127_7529054_3 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 453.0
HKD3_k127_7529054_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 327.0
HKD3_k127_7529054_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000001106 237.0
HKD3_k127_7529054_6 Jag_N K06346 - - 0.00000000000000000000000000000000000000000000000000000000000000000007016 237.0
HKD3_k127_7529054_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000002894 204.0
HKD3_k127_7568191_0 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 581.0
HKD3_k127_7568191_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 348.0
HKD3_k127_7568191_2 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000008014 151.0
HKD3_k127_7568191_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000481 143.0
HKD3_k127_7605575_0 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008636 317.0
HKD3_k127_7605575_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000443 259.0
HKD3_k127_7605575_2 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000008242 199.0
HKD3_k127_7605575_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000008155 149.0
HKD3_k127_7653200_0 AMP-dependent synthetase and ligase K01895,K08295 - 6.2.1.1,6.2.1.32 2.366e-276 856.0
HKD3_k127_7653200_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009662 365.0
HKD3_k127_7653200_2 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000003109 208.0
HKD3_k127_7653200_3 family 9 - - - 0.000000000000000000000000000000000000000000000006461 186.0
HKD3_k127_7653200_4 Glycosyl transferases group 1 K06338 - - 0.0000000000000000000000000000000000000006574 164.0
HKD3_k127_7653200_5 Trypsin-like peptidase domain - - - 0.000000000000000000000000000000000000001167 158.0
HKD3_k127_7653200_6 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.000000000000000002406 98.0
HKD3_k127_7654493_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 5.098e-221 689.0
HKD3_k127_7654493_1 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 3.977e-207 653.0
HKD3_k127_7654493_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 327.0
HKD3_k127_7654493_11 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 333.0
HKD3_k127_7654493_12 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000001126 226.0
HKD3_k127_7654493_13 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000003002 190.0
HKD3_k127_7654493_14 integral membrane protein - - - 0.000000000000000000000000000000000000000000962 162.0
HKD3_k127_7654493_15 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000001606 125.0
HKD3_k127_7654493_16 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000001839 96.0
HKD3_k127_7654493_17 glycosyltransferase involved in LPS biosynthesis K07270 - - 0.000000000000001796 89.0
HKD3_k127_7654493_18 monooxygenase activity - - - 0.00000000000002013 76.0
HKD3_k127_7654493_19 - - - - 0.000000002432 66.0
HKD3_k127_7654493_2 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 604.0
HKD3_k127_7654493_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 599.0
HKD3_k127_7654493_4 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 544.0
HKD3_k127_7654493_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 451.0
HKD3_k127_7654493_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 447.0
HKD3_k127_7654493_7 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 400.0
HKD3_k127_7654493_8 fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 355.0
HKD3_k127_7654493_9 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 342.0
HKD3_k127_7768747_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 605.0
HKD3_k127_7768747_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 597.0
HKD3_k127_7768747_10 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000001462 71.0
HKD3_k127_7768747_11 Transposase is116 is110 is902 family K07486 - - 0.000001582 49.0
HKD3_k127_7768747_2 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 534.0
HKD3_k127_7768747_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007437 388.0
HKD3_k127_7768747_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004013 249.0
HKD3_k127_7768747_5 Jag_N K06346 - - 0.000000000000000000000000000000000000000000000000000000000000000000002889 241.0
HKD3_k127_7768747_6 MerR HTH family regulatory protein - - - 0.00000000000000000000000000000000000000000000000000006824 196.0
HKD3_k127_7768747_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000008403 151.0
HKD3_k127_7768747_8 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000000000000003647 123.0
HKD3_k127_7768747_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000188 106.0
HKD3_k127_7806979_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.472e-314 972.0
HKD3_k127_7806979_1 PFAM malic K00027,K00029 - 1.1.1.38,1.1.1.40 9.759e-238 749.0
HKD3_k127_7806979_2 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 478.0
HKD3_k127_7806979_3 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009814 379.0
HKD3_k127_7806979_4 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 350.0
HKD3_k127_7806979_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000003401 80.0
HKD3_k127_7818988_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 392.0
HKD3_k127_7818988_1 PFAM glycosyl transferase, family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 340.0
HKD3_k127_7818988_2 PFAM Glycosyl transferase, group 1 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 310.0
HKD3_k127_7818988_3 PFAM glycosyl transferase, family 9 K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 307.0
HKD3_k127_7818988_4 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 297.0
HKD3_k127_7818988_5 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009549 291.0
HKD3_k127_7818988_6 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000098 283.0
HKD3_k127_7818988_7 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000043 248.0
HKD3_k127_7818988_8 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000002017 102.0
HKD3_k127_7818988_9 Pyridoxamine 5'-phosphate oxidase - - - 0.00001841 53.0
HKD3_k127_7830884_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 587.0
HKD3_k127_7830884_1 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 373.0
HKD3_k127_7830884_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 322.0
HKD3_k127_7830884_3 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 305.0
HKD3_k127_7830884_4 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 293.0
HKD3_k127_7830884_5 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000747 216.0
HKD3_k127_7830884_6 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000003169 68.0
HKD3_k127_7830884_7 PFAM FecR protein - - - 0.0000000004412 70.0
HKD3_k127_7830884_8 Calcineurin-like phosphoesterase - - - 0.00000006771 64.0
HKD3_k127_7830884_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000009054 53.0
HKD3_k127_7887864_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 528.0
HKD3_k127_7887864_1 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 462.0
HKD3_k127_7887864_10 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000000006258 167.0
HKD3_k127_7887864_11 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000000000001282 159.0
HKD3_k127_7887864_12 OstA-like protein K09774 - - 0.000000000000000000000000000000000001588 147.0
HKD3_k127_7887864_13 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000000000000000000002551 129.0
HKD3_k127_7887864_14 Lipopolysaccharide-assembly, LptC-related - - - 0.000000000000000003376 92.0
HKD3_k127_7887864_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 396.0
HKD3_k127_7887864_3 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 380.0
HKD3_k127_7887864_4 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 378.0
HKD3_k127_7887864_5 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 358.0
HKD3_k127_7887864_6 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 338.0
HKD3_k127_7887864_7 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000006001 203.0
HKD3_k127_7887864_8 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000006925 203.0
HKD3_k127_7887864_9 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000000000000000000001946 196.0
HKD3_k127_7970315_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 499.0
HKD3_k127_7970315_1 PFAM Peptidase M20 K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 293.0
HKD3_k127_7970315_2 Protein of unknown function (DUF1641) - - - 0.00000000000000000000000000000000000000000000000000286 190.0
HKD3_k127_7970315_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000805 128.0
HKD3_k127_7970315_4 Transposase is116 is110 is902 family K07486 - - 0.000001216 50.0
HKD3_k127_8103223_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 611.0
HKD3_k127_8103223_1 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 513.0
HKD3_k127_8103223_10 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 276.0
HKD3_k127_8103223_11 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000002368 249.0
HKD3_k127_8103223_12 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000465 196.0
HKD3_k127_8103223_13 HicB family - - - 0.000000000000000000000000000000000000000000000000003724 183.0
HKD3_k127_8103223_14 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000001783 176.0
HKD3_k127_8103223_15 - - - - 0.0000000000000000000007749 97.0
HKD3_k127_8103223_16 nuclease activity K06218 - - 0.0000000000000000009883 88.0
HKD3_k127_8103223_18 - - - - 0.000000007143 62.0
HKD3_k127_8103223_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000768 495.0
HKD3_k127_8103223_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 437.0
HKD3_k127_8103223_4 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 435.0
HKD3_k127_8103223_5 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 409.0
HKD3_k127_8103223_6 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 405.0
HKD3_k127_8103223_7 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 381.0
HKD3_k127_8103223_8 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 343.0
HKD3_k127_8103223_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009668 281.0
HKD3_k127_8131668_0 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 525.0
HKD3_k127_8131668_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 413.0
HKD3_k127_8131668_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 398.0
HKD3_k127_8131668_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007562 257.0
HKD3_k127_8131668_4 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000001416 216.0
HKD3_k127_8131668_5 MOSC domain - - - 0.00000000000000000000000000000000000000000000000007595 183.0
HKD3_k127_8131668_6 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000005887 127.0
HKD3_k127_8131668_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000008669 78.0
HKD3_k127_8131668_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000001173 70.0
HKD3_k127_8139913_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.564e-207 657.0
HKD3_k127_8139913_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 1.346e-202 636.0
HKD3_k127_8139913_10 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000018 163.0
HKD3_k127_8139913_11 Universal stress protein family - - - 0.00000000000000000000000000003375 123.0
HKD3_k127_8139913_12 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000004171 115.0
HKD3_k127_8139913_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 520.0
HKD3_k127_8139913_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 445.0
HKD3_k127_8139913_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 408.0
HKD3_k127_8139913_5 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 360.0
HKD3_k127_8139913_6 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 248.0
HKD3_k127_8139913_7 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000002516 236.0
HKD3_k127_8139913_9 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000001772 204.0
HKD3_k127_8226498_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.512e-202 644.0
HKD3_k127_8226498_1 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 562.0
HKD3_k127_8226498_10 - - - - 0.000000000000000000000000000000003861 132.0
HKD3_k127_8226498_11 TIGRFAM 4-oxalocrotonate tautomerase family enzyme K01821 - 5.3.2.6 0.00000000000000000000000000004181 117.0
HKD3_k127_8226498_12 - - - - 0.00000000000000000000001842 101.0
HKD3_k127_8226498_13 - - - - 0.0000000000000000001564 95.0
HKD3_k127_8226498_14 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000000000002025 90.0
HKD3_k127_8226498_15 Plasmid stabilization system - - - 0.000000000000000005534 86.0
HKD3_k127_8226498_16 - - - - 0.00000000000000001251 85.0
HKD3_k127_8226498_17 - - - - 0.00000000000001265 78.0
HKD3_k127_8226498_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 453.0
HKD3_k127_8226498_3 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 310.0
HKD3_k127_8226498_4 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001061 281.0
HKD3_k127_8226498_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001957 260.0
HKD3_k127_8226498_6 COG3634 Alkyl hydroperoxide reductase, large subunit K03387 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008785,GO:0009321,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1902494,GO:1990204 - 0.00000000000000000000000000000000000000000000000000000000000000000001243 246.0
HKD3_k127_8226498_7 PFAM molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000004975 218.0
HKD3_k127_8226498_8 - - - - 0.000000000000000000000000000000000000000000000000000000008648 206.0
HKD3_k127_8645788_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1101.0
HKD3_k127_8645788_1 RNB K12573 - - 5.867e-240 763.0
HKD3_k127_8645788_10 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000002351 141.0
HKD3_k127_8645788_11 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000004566 92.0
HKD3_k127_8645788_12 Carbon-nitrogen hydrolase - - - 0.0009444 49.0
HKD3_k127_8645788_2 Belongs to the NifD NifK NifE NifN family K02592 - - 5.017e-205 648.0
HKD3_k127_8645788_3 Belongs to the NifD NifK NifE NifN family K02587 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 595.0
HKD3_k127_8645788_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 592.0
HKD3_k127_8645788_5 TIGRFAM Nitrogenase cofactor biosynthesis protein NifB K02585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 582.0
HKD3_k127_8645788_6 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 429.0
HKD3_k127_8645788_7 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 411.0
HKD3_k127_8645788_8 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001024 253.0
HKD3_k127_8645788_9 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007815 253.0
HKD3_k127_8690357_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 2.836e-311 966.0
HKD3_k127_8690357_1 Pyridine nucleotide-disulphide oxidoreductase K15022 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 580.0
HKD3_k127_8690357_10 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000007733 69.0
HKD3_k127_8690357_11 PFAM cytochrome c - - - 0.0000007104 57.0
HKD3_k127_8690357_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 520.0
HKD3_k127_8690357_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009597 457.0
HKD3_k127_8690357_4 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 423.0
HKD3_k127_8690357_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 284.0
HKD3_k127_8690357_6 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006147 254.0
HKD3_k127_8690357_7 NADH dehydrogenase K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001572 210.0
HKD3_k127_8690357_8 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000005651 166.0
HKD3_k127_8690357_9 - - - - 0.0000000000000000000000000000000000006098 146.0
HKD3_k127_8697185_0 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 485.0
HKD3_k127_8697185_1 SMART Elongator protein 3 MiaB NifB K07139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 382.0
HKD3_k127_8697185_10 metal-dependent membrane protease K07052 - - 0.0000214 53.0
HKD3_k127_8697185_2 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 331.0
HKD3_k127_8697185_3 Xylose isomerase-like TIM barrel K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000003943 271.0
HKD3_k127_8697185_4 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003207 258.0
HKD3_k127_8697185_5 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000003181 216.0
HKD3_k127_8697185_6 PFAM Lytic K08309 - - 0.00000000000000000000000000000000000000000006762 173.0
HKD3_k127_8697185_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000189 111.0
HKD3_k127_8697185_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000008147 81.0
HKD3_k127_8697185_9 Putative regulatory protein - - - 0.0000000001443 63.0
HKD3_k127_8723282_0 DNA replication proofreading K02336,K06877 - 2.7.7.7 1.21e-278 876.0
HKD3_k127_8723282_1 Pterin binding enzyme K15023 - 2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 466.0
HKD3_k127_8723282_2 - - - - 0.00000000000000000000000000000006509 126.0
HKD3_k127_8723282_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000000000004563 102.0
HKD3_k127_8723282_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000001031 73.0
HKD3_k127_8759819_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.291e-211 663.0
HKD3_k127_8759819_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 582.0
HKD3_k127_8759819_10 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000002885 181.0
HKD3_k127_8759819_11 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000007058 114.0
HKD3_k127_8759819_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005016 530.0
HKD3_k127_8759819_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 471.0
HKD3_k127_8759819_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 354.0
HKD3_k127_8759819_5 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 331.0
HKD3_k127_8759819_6 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008634 241.0
HKD3_k127_8759819_7 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 232.0
HKD3_k127_8759819_8 decarboxylase K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000001655 205.0
HKD3_k127_8759819_9 sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000001719 198.0
HKD3_k127_8771889_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004976 606.0
HKD3_k127_8771889_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 435.0
HKD3_k127_8771889_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 391.0
HKD3_k127_8771889_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
HKD3_k127_8771889_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K12976,K16079,K22110 - - 0.0000000000000000000000000000000000000000000000000000000001024 214.0
HKD3_k127_8771889_5 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000003627 146.0
HKD3_k127_8771889_6 PFAM CBS domain containing protein - - - 0.0000000000000000000000004883 115.0
HKD3_k127_8771889_7 Tetratricopeptide repeat-like domain - - - 0.00003094 54.0
HKD3_k127_8932452_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1336.0
HKD3_k127_8932452_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 563.0
HKD3_k127_8932452_10 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000003008 174.0
HKD3_k127_8932452_11 - - - - 0.000000001233 61.0
HKD3_k127_8932452_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 522.0
HKD3_k127_8932452_3 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 364.0
HKD3_k127_8932452_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 349.0
HKD3_k127_8932452_5 Transmembrane sensor domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 310.0
HKD3_k127_8932452_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 293.0
HKD3_k127_8932452_7 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005118 292.0
HKD3_k127_8932452_8 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
HKD3_k127_8932452_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000003296 255.0
HKD3_k127_9073288_0 4Fe-4S dicluster domain - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.729e-264 818.0
HKD3_k127_9073288_1 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 581.0
HKD3_k127_9073288_10 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 367.0
HKD3_k127_9073288_11 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
HKD3_k127_9073288_12 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 333.0
HKD3_k127_9073288_13 Bax inhibitor 1 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 331.0
HKD3_k127_9073288_14 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 332.0
HKD3_k127_9073288_15 nitrate reductase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 295.0
HKD3_k127_9073288_16 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002954 295.0
HKD3_k127_9073288_17 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001791 277.0
HKD3_k127_9073288_18 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001048 279.0
HKD3_k127_9073288_19 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000346 265.0
HKD3_k127_9073288_2 PFAM cytochrome c class III - GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 563.0
HKD3_k127_9073288_20 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004987 248.0
HKD3_k127_9073288_21 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004559 241.0
HKD3_k127_9073288_22 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000001063 226.0
HKD3_k127_9073288_23 ubiE/COQ5 methyltransferase family K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000001369 209.0
HKD3_k127_9073288_24 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000004915 205.0
HKD3_k127_9073288_25 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000006013 205.0
HKD3_k127_9073288_26 Protein of unknown function, DUF599 - - - 0.00000000000000000000000000000000000000000000000000009319 193.0
HKD3_k127_9073288_27 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000002694 188.0
HKD3_k127_9073288_28 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000001901 178.0
HKD3_k127_9073288_29 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000001468 158.0
HKD3_k127_9073288_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 563.0
HKD3_k127_9073288_30 Transcriptional regulator - - - 0.00000000000000000000000000000000000000307 159.0
HKD3_k127_9073288_31 PFAM Aldehyde dehydrogenase family K00128,K00130,K00131,K00151,K10217 - 1.2.1.3,1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85,1.2.1.9 0.000000000000000000000000000009193 133.0
HKD3_k127_9073288_32 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000006441 123.0
HKD3_k127_9073288_33 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000000000000000008277 117.0
HKD3_k127_9073288_34 - - - - 0.0000000000000000001943 91.0
HKD3_k127_9073288_35 Sulfurtransferase TusA - - - 0.0000000000000000003501 89.0
HKD3_k127_9073288_36 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000002466 84.0
HKD3_k127_9073288_38 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.0000000000002235 81.0
HKD3_k127_9073288_4 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 517.0
HKD3_k127_9073288_40 - - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000001393 64.0
HKD3_k127_9073288_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 445.0
HKD3_k127_9073288_6 response to heat K03696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 425.0
HKD3_k127_9073288_7 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 409.0
HKD3_k127_9073288_8 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 401.0
HKD3_k127_9073288_9 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 389.0
HKD3_k127_91138_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.28e-284 912.0
HKD3_k127_91138_1 class II (D, K and N) K01893 - 6.1.1.22 8.874e-199 627.0
HKD3_k127_91138_2 molybdopterin oxidoreductase Fe4S4 region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 580.0
HKD3_k127_91138_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 497.0
HKD3_k127_91138_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 487.0
HKD3_k127_91138_5 Histidine kinase K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 454.0
HKD3_k127_91138_6 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000002563 220.0
HKD3_k127_91138_7 PpiC-type peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001314 224.0
HKD3_k127_91138_8 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000002266 93.0
HKD3_k127_91138_9 A translational regulator that binds mRNA to regulate translation initiation and or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome- binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW K03563 - - 0.00000000001806 75.0
HKD3_k127_9163026_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 9.778e-290 908.0
HKD3_k127_9163026_1 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 6.683e-249 797.0
HKD3_k127_9163026_2 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 363.0
HKD3_k127_9163026_3 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 329.0
HKD3_k127_9163026_4 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003712 280.0
HKD3_k127_9163026_5 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
HKD3_k127_9163026_6 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000001647 217.0
HKD3_k127_9163026_7 PFAM NLP P60 protein K19223 - - 0.0000000000000000000000000000000000000000002138 169.0
HKD3_k127_9163026_8 - - - - 0.00000000000000000000000000000000003617 140.0
HKD3_k127_9163026_9 translation initiation factor activity - - - 0.00004881 53.0
HKD3_k127_9204206_0 PFAM alpha amylase, catalytic K06044 - 5.4.99.15 0.0 1097.0
HKD3_k127_9204206_1 Domain of unknown function (DUF3536) - - - 0.0 1030.0
HKD3_k127_9204206_10 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009473 505.0
HKD3_k127_9204206_11 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 494.0
HKD3_k127_9204206_12 Amino-transferase class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 477.0
HKD3_k127_9204206_13 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 452.0
HKD3_k127_9204206_14 DNA methylase K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 443.0
HKD3_k127_9204206_15 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 424.0
HKD3_k127_9204206_16 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 374.0
HKD3_k127_9204206_17 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 381.0
HKD3_k127_9204206_18 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 365.0
HKD3_k127_9204206_19 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 358.0
HKD3_k127_9204206_2 Domain of unknown function (DUF3459) K00700,K01236 - 2.4.1.18,3.2.1.141 1.815e-237 749.0
HKD3_k127_9204206_20 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 336.0
HKD3_k127_9204206_21 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 315.0
HKD3_k127_9204206_22 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 304.0
HKD3_k127_9204206_23 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 291.0
HKD3_k127_9204206_24 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000008898 260.0
HKD3_k127_9204206_25 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002665 255.0
HKD3_k127_9204206_26 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001942 252.0
HKD3_k127_9204206_28 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001138 248.0
HKD3_k127_9204206_29 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000002079 243.0
HKD3_k127_9204206_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 2.191e-210 663.0
HKD3_k127_9204206_30 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000001198 225.0
HKD3_k127_9204206_31 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000245 193.0
HKD3_k127_9204206_32 CBS domain K04767,K07168,K07182 - - 0.0000000000000000000000000000000000000000000000000001235 188.0
HKD3_k127_9204206_33 - - - - 0.00000000000000000000000000000000000000000000000001364 187.0
HKD3_k127_9204206_34 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000002031 172.0
HKD3_k127_9204206_35 NusB family K03625 - - 0.000000000000000000000000000000000000001433 151.0
HKD3_k127_9204206_36 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001027 151.0
HKD3_k127_9204206_37 - - - - 0.00000000000000000000000000000001001 130.0
HKD3_k127_9204206_39 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001205 119.0
HKD3_k127_9204206_4 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 8.275e-199 625.0
HKD3_k127_9204206_40 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000001005 120.0
HKD3_k127_9204206_41 mRNA binding - - - 0.0000000000000000000000000002416 115.0
HKD3_k127_9204206_42 Predicted membrane protein (DUF2232) - - - 0.00000000000000000000000001229 121.0
HKD3_k127_9204206_43 monooxygenase activity - - - 0.00000000000000000000003389 106.0
HKD3_k127_9204206_44 Beta-1,3-glucanase - - - 0.00000000000000000000008308 112.0
HKD3_k127_9204206_45 cell cycle K05589,K12065,K13052 - - 0.000000000000000000003672 100.0
HKD3_k127_9204206_46 protein homooligomerization - - - 0.00000000000000000002202 105.0
HKD3_k127_9204206_47 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000007758 90.0
HKD3_k127_9204206_48 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000001693 72.0
HKD3_k127_9204206_49 3D domain protein - - - 0.00000000000687 73.0
HKD3_k127_9204206_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 602.0
HKD3_k127_9204206_50 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000002803 59.0
HKD3_k127_9204206_51 Belongs to the sulfur carrier protein TusA family - - - 0.00000005125 57.0
HKD3_k127_9204206_52 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00002314 47.0
HKD3_k127_9204206_53 - - - - 0.00006767 49.0
HKD3_k127_9204206_6 Glycosyl transferase family group 2 K00752,K11936 - 2.4.1.212 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 596.0
HKD3_k127_9204206_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 564.0
HKD3_k127_9204206_8 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 567.0
HKD3_k127_9204206_9 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 550.0
HKD3_k127_9288067_0 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 1.542e-217 680.0
HKD3_k127_9288067_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 585.0
HKD3_k127_9288067_2 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 564.0
HKD3_k127_9288067_3 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008725 393.0
HKD3_k127_9288067_4 Metallo-beta-lactamase superfamily domain K07576 - - 0.000000000000000000000001518 105.0
HKD3_k127_9288067_5 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000000000000000005909 100.0
HKD3_k127_9288067_6 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000002123 91.0
HKD3_k127_9288067_7 Domain of unknown function (DUF4282) - - - 0.0000000000000001142 83.0
HKD3_k127_9349113_0 Peptidase family U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008459 535.0
HKD3_k127_9349113_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 454.0
HKD3_k127_9349113_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 363.0
HKD3_k127_9349113_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000000000000000000000000000000000000000000000000000000178 203.0
HKD3_k127_9349113_5 Transposase is116 is110 is902 family K07486 - - 0.000001216 50.0
HKD3_k127_9349777_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1082.0
HKD3_k127_9349777_1 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.0000000000000000000000126 106.0
HKD3_k127_9349777_2 protein trimerization - - - 0.0000001527 60.0
HKD3_k127_99919_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1671.0
HKD3_k127_99919_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 514.0
HKD3_k127_99919_2 PFAM Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 396.0
HKD3_k127_99919_3 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 369.0
HKD3_k127_99919_4 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000007447 177.0
HKD3_k127_99919_5 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000004983 140.0