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Overview

ID MAG01871
Name HKD3_bin.68
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus Calidifontimicrobium
Species
Assembly information
Completeness (%) 85.16
Contamination (%) 5.94
GC content (%) 72.0
N50 (bp) 23,499
Genome size (bp) 3,554,350

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3368

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_101450_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 591.0
HKD3_k127_101450_1 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 536.0
HKD3_k127_101450_2 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 351.0
HKD3_k127_101450_3 short-chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000002527 224.0
HKD3_k127_101450_4 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000006318 192.0
HKD3_k127_101450_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000083 115.0
HKD3_k127_1019867_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.0 1028.0
HKD3_k127_1019867_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000003545 153.0
HKD3_k127_1019867_2 CBS domain - - - 0.000000000000000000003175 93.0
HKD3_k127_1019867_3 Protein of unknown function (DUF3047) - - - 0.000000000000000009297 99.0
HKD3_k127_1214855_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 2.448e-273 854.0
HKD3_k127_1214855_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 557.0
HKD3_k127_1214855_10 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001252 253.0
HKD3_k127_1214855_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000001248 222.0
HKD3_k127_1214855_12 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000005907 228.0
HKD3_k127_1214855_13 Alpha beta K07018 - - 0.000000000000000000000000000000000000000000000000000000000000006998 245.0
HKD3_k127_1214855_14 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000002396 209.0
HKD3_k127_1214855_15 Ferredoxin - - - 0.000000000000000000000000000000000000000000000001769 175.0
HKD3_k127_1214855_16 HIT domain - - - 0.0000000000000000000000000000000000000000000002095 171.0
HKD3_k127_1214855_17 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000002478 168.0
HKD3_k127_1214855_18 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000001315 161.0
HKD3_k127_1214855_19 - - - - 0.000000000000000000000000000000000006016 153.0
HKD3_k127_1214855_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 452.0
HKD3_k127_1214855_20 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000002569 147.0
HKD3_k127_1214855_21 TIGRFAM phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000003206 130.0
HKD3_k127_1214855_22 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000001366 135.0
HKD3_k127_1214855_23 PFAM Sporulation domain protein - - - 0.000000000000000000000000000005598 128.0
HKD3_k127_1214855_24 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000493 121.0
HKD3_k127_1214855_25 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000001111 122.0
HKD3_k127_1214855_26 - - - - 0.00000000000003237 80.0
HKD3_k127_1214855_27 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000007959 74.0
HKD3_k127_1214855_28 - - - - 0.00004156 46.0
HKD3_k127_1214855_3 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 361.0
HKD3_k127_1214855_4 Domain of unknown function (DUF3400) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 338.0
HKD3_k127_1214855_5 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 315.0
HKD3_k127_1214855_6 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006396 289.0
HKD3_k127_1214855_7 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006128 283.0
HKD3_k127_1214855_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001055 281.0
HKD3_k127_1214855_9 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003753 299.0
HKD3_k127_1293979_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1397.0
HKD3_k127_1293979_1 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 3.455e-265 818.0
HKD3_k127_1293979_10 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 336.0
HKD3_k127_1293979_11 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 305.0
HKD3_k127_1293979_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 287.0
HKD3_k127_1293979_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 276.0
HKD3_k127_1293979_14 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000000000008714 215.0
HKD3_k127_1293979_15 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000006348 185.0
HKD3_k127_1293979_16 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000001029 126.0
HKD3_k127_1293979_17 - - - - 0.000000000000000004994 91.0
HKD3_k127_1293979_18 Protein conserved in bacteria K09926 - - 0.0000000001778 72.0
HKD3_k127_1293979_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.722e-239 746.0
HKD3_k127_1293979_3 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 1.313e-226 711.0
HKD3_k127_1293979_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006451 578.0
HKD3_k127_1293979_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 458.0
HKD3_k127_1293979_6 cytochrome C oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 417.0
HKD3_k127_1293979_7 Regulator K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 403.0
HKD3_k127_1293979_8 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 351.0
HKD3_k127_1293979_9 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 346.0
HKD3_k127_1325768_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 563.0
HKD3_k127_1325768_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 538.0
HKD3_k127_1325768_2 Diguanylate cyclase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 529.0
HKD3_k127_1325768_3 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 379.0
HKD3_k127_1325768_4 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000000000000000000001051 166.0
HKD3_k127_1325768_5 - - - - 0.000000000000000000000000000007627 123.0
HKD3_k127_1338306_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.531e-240 749.0
HKD3_k127_1338306_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.007e-234 738.0
HKD3_k127_1338306_10 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000009507 235.0
HKD3_k127_1338306_11 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.000000000000000000000000000000000000000000000000000000007667 204.0
HKD3_k127_1338306_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 598.0
HKD3_k127_1338306_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 539.0
HKD3_k127_1338306_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 488.0
HKD3_k127_1338306_5 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 459.0
HKD3_k127_1338306_6 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 407.0
HKD3_k127_1338306_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 410.0
HKD3_k127_1338306_8 TIGRFAM phosphate regulon sensor kinase PhoR K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 392.0
HKD3_k127_1338306_9 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 362.0
HKD3_k127_1343576_0 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1022.0
HKD3_k127_1343576_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 7.033e-218 685.0
HKD3_k127_1343576_2 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 583.0
HKD3_k127_1343576_3 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 306.0
HKD3_k127_1343576_4 LemA family K03744 - - 0.00000000000000000000000000000000001586 142.0
HKD3_k127_1343576_5 cytochrome - - - 0.000000000000000000000001122 116.0
HKD3_k127_1350117_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1273.0
HKD3_k127_1350117_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1209.0
HKD3_k127_1350117_10 Protein of unknown function DUF45 - - - 0.00008238 49.0
HKD3_k127_1350117_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.317e-195 614.0
HKD3_k127_1350117_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 471.0
HKD3_k127_1350117_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 366.0
HKD3_k127_1350117_5 Flagellar basal body rod protein K02391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 338.0
HKD3_k127_1350117_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 321.0
HKD3_k127_1350117_7 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000001251 210.0
HKD3_k127_1350117_8 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000000009744 128.0
HKD3_k127_1350117_9 Gram-negative porin - - - 0.0000000000000000000000009008 118.0
HKD3_k127_1351790_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0 1000.0
HKD3_k127_1351790_1 PFAM acyl-CoA dehydrogenase domain protein K00253 - 1.3.8.4 2.257e-235 732.0
HKD3_k127_1351790_2 Belongs to the thiolase family K00626 - 2.3.1.9 3.945e-217 678.0
HKD3_k127_1351790_3 PFAM acyl-CoA dehydrogenase domain protein - - - 9.734e-217 679.0
HKD3_k127_1351790_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 358.0
HKD3_k127_1351790_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 297.0
HKD3_k127_1351790_6 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006861 231.0
HKD3_k127_1351790_7 Belongs to the enoyl-CoA hydratase isomerase family K13766 - 4.2.1.18 0.00000000000000000009354 94.0
HKD3_k127_1357963_0 cytochrome C K02198 - - 5.37e-294 925.0
HKD3_k127_1357963_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 6.885e-228 711.0
HKD3_k127_1357963_2 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 599.0
HKD3_k127_1357963_3 Aldehyde dehydrogenase family K00130,K09472,K12254 - 1.2.1.54,1.2.1.8,1.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 584.0
HKD3_k127_1357963_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 536.0
HKD3_k127_1357963_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 421.0
HKD3_k127_1357963_6 TIGRFAM cytochrome c-type biogenesis protein CcmI K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002935 282.0
HKD3_k127_1357963_7 Periplasmic protein thiol disulfide oxidoreductase DsbE K02199 - - 0.00000000000000000000000000000000000000000000000000000000000007087 243.0
HKD3_k127_1357963_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000003807 204.0
HKD3_k127_1357963_9 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000006831 165.0
HKD3_k127_1409288_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1026.0
HKD3_k127_1409288_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.053e-211 674.0
HKD3_k127_1409288_10 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000002052 265.0
HKD3_k127_1409288_11 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000008684 152.0
HKD3_k127_1409288_12 Integral membrane protein TerC family - - - 0.000000000000000000000649 95.0
HKD3_k127_1409288_2 two-component sensor kinase K07649 - 2.7.13.3 1.817e-206 652.0
HKD3_k127_1409288_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 4.519e-198 621.0
HKD3_k127_1409288_4 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 533.0
HKD3_k127_1409288_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 568.0
HKD3_k127_1409288_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902,K08692 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5,6.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 532.0
HKD3_k127_1409288_7 PFAM response regulator receiver K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 415.0
HKD3_k127_1409288_8 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 357.0
HKD3_k127_1409288_9 Rod shape-determining protein mreD K03571 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003284 269.0
HKD3_k127_141639_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.807e-276 856.0
HKD3_k127_141639_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 6.877e-253 784.0
HKD3_k127_141639_10 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000315 72.0
HKD3_k127_141639_11 PFAM 17 kDa surface antigen - - - 0.0000000004439 66.0
HKD3_k127_141639_12 - - - - 0.00000001081 57.0
HKD3_k127_141639_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.114e-237 746.0
HKD3_k127_141639_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 6.812e-207 675.0
HKD3_k127_141639_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 3.865e-206 649.0
HKD3_k127_141639_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 539.0
HKD3_k127_141639_6 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 398.0
HKD3_k127_141639_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 326.0
HKD3_k127_141639_8 Colicin V production protein K03558 - - 0.000000000000000000000000000000000000000000000000003081 199.0
HKD3_k127_141639_9 PFAM Sporulation domain protein K03749 - - 0.0000000000000000000000000000000000000000002896 168.0
HKD3_k127_144263_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 7.494e-279 864.0
HKD3_k127_144263_1 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 493.0
HKD3_k127_144263_2 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 488.0
HKD3_k127_144263_3 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 320.0
HKD3_k127_144263_4 Response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000004054 241.0
HKD3_k127_1491265_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1087.0
HKD3_k127_1491265_1 PFAM acyl-CoA dehydrogenase domain protein - - - 3.828e-223 710.0
HKD3_k127_1491265_2 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 550.0
HKD3_k127_1491265_3 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 415.0
HKD3_k127_1491265_4 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 388.0
HKD3_k127_1491265_5 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 331.0
HKD3_k127_1491265_6 PFAM binding-protein-dependent transport systems inner membrane component K05773,K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006543 282.0
HKD3_k127_1491265_7 ABC transporter K06857 - 3.6.3.55 0.00000000000000000000001664 103.0
HKD3_k127_1501416_0 CHAT domain - - - 0.0 1919.0
HKD3_k127_1501416_1 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 1.488e-264 817.0
HKD3_k127_1501416_10 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 335.0
HKD3_k127_1501416_11 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 299.0
HKD3_k127_1501416_12 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 287.0
HKD3_k127_1501416_13 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000272 297.0
HKD3_k127_1501416_14 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003181 252.0
HKD3_k127_1501416_15 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001693 254.0
HKD3_k127_1501416_16 carboxymethylenebutenolidase activity K01061,K07100 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000002835 244.0
HKD3_k127_1501416_17 Ankyrin repeats (many copies) K06867 - - 0.0000000000000000000000000000000000000000000000000000000000004287 229.0
HKD3_k127_1501416_18 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001798 209.0
HKD3_k127_1501416_19 pilus assembly K02676 - - 0.000000000000000000000000000000000000000000000000000001133 210.0
HKD3_k127_1501416_2 Aminotransferase class-III K01845 - 5.4.3.8 1.34e-198 629.0
HKD3_k127_1501416_20 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000006208 170.0
HKD3_k127_1501416_21 Protein required for attachment to host cells - - - 0.00000000000000003491 87.0
HKD3_k127_1501416_22 Domain of unknown function (DUF4936) - - - 0.00000002013 63.0
HKD3_k127_1501416_23 - - - - 0.000005218 54.0
HKD3_k127_1501416_3 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 5.476e-198 640.0
HKD3_k127_1501416_4 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 518.0
HKD3_k127_1501416_5 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 453.0
HKD3_k127_1501416_6 Alpha beta hydrolase K01066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 452.0
HKD3_k127_1501416_7 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 394.0
HKD3_k127_1501416_8 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 384.0
HKD3_k127_1501416_9 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 340.0
HKD3_k127_1524376_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1161.0
HKD3_k127_1524376_1 AMP-binding enzyme C-terminal domain K00666 - - 1.656e-282 877.0
HKD3_k127_1524376_10 NlpB/DapX lipoprotein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 366.0
HKD3_k127_1524376_11 MarR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 314.0
HKD3_k127_1524376_12 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 296.0
HKD3_k127_1524376_13 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002105 302.0
HKD3_k127_1524376_14 Uncharacterised protein family (UPF0149) K07039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000527 288.0
HKD3_k127_1524376_15 peptidylprolyl isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002586 254.0
HKD3_k127_1524376_16 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000001511 265.0
HKD3_k127_1524376_17 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000545 241.0
HKD3_k127_1524376_18 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005531 246.0
HKD3_k127_1524376_19 Acetyltransferase (GNAT) domain K03825 - - 0.0000000000000000000000000000000000000000000000000000007817 197.0
HKD3_k127_1524376_2 PFAM cytochrome bd ubiquinol oxidase subunit I K00425 - 1.10.3.14 1.309e-241 762.0
HKD3_k127_1524376_20 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000003047 158.0
HKD3_k127_1524376_21 - - - - 0.0000000000000000000005413 106.0
HKD3_k127_1524376_22 Flavinator of succinate dehydrogenase K09159 - - 0.0000003738 56.0
HKD3_k127_1524376_3 Major facilitator superfamily - - - 3.605e-203 640.0
HKD3_k127_1524376_4 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 611.0
HKD3_k127_1524376_5 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 583.0
HKD3_k127_1524376_6 cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 501.0
HKD3_k127_1524376_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 489.0
HKD3_k127_1524376_8 A domain family that is part of the cupin metalloenzyme superfamily. K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 471.0
HKD3_k127_1524376_9 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 408.0
HKD3_k127_1540377_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0 996.0
HKD3_k127_1540377_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261 - 1.4.1.2,1.4.1.3 5.884e-240 747.0
HKD3_k127_1540377_10 Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 499.0
HKD3_k127_1540377_11 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 459.0
HKD3_k127_1540377_12 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 452.0
HKD3_k127_1540377_13 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 401.0
HKD3_k127_1540377_14 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 340.0
HKD3_k127_1540377_15 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 317.0
HKD3_k127_1540377_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 298.0
HKD3_k127_1540377_17 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 293.0
HKD3_k127_1540377_18 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004565 275.0
HKD3_k127_1540377_19 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007006 285.0
HKD3_k127_1540377_2 twitching motility protein K02670 - - 4.2e-224 698.0
HKD3_k127_1540377_20 Protein of unknown function (DUF2946) - - - 0.0000000000000000000000000000000000000000000000000000000000000006507 240.0
HKD3_k127_1540377_21 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000003369 216.0
HKD3_k127_1540377_22 BON domain - - - 0.000000000000000000000000000000000000000000000000000000000003715 214.0
HKD3_k127_1540377_23 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000001339 214.0
HKD3_k127_1540377_24 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000005826 198.0
HKD3_k127_1540377_25 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000000000003921 175.0
HKD3_k127_1540377_26 - - - - 0.00000000000000000000000000000000000000000005894 165.0
HKD3_k127_1540377_27 - - - - 0.000000000000000000000000000000000000000002082 159.0
HKD3_k127_1540377_28 Zinc-finger domain - - - 0.0000000000000000000000000007778 113.0
HKD3_k127_1540377_29 - - - - 0.00000000000000000000000009012 114.0
HKD3_k127_1540377_3 PFAM NUDIX hydrolase - - - 2.218e-214 681.0
HKD3_k127_1540377_30 - - - - 0.000000000000000005593 88.0
HKD3_k127_1540377_4 twitching motility protein K02669,K12203 - - 1.636e-209 653.0
HKD3_k127_1540377_5 Belongs to the thiolase family K00626 - 2.3.1.9 4.489e-207 651.0
HKD3_k127_1540377_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 574.0
HKD3_k127_1540377_7 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 554.0
HKD3_k127_1540377_8 carnitine dehydratase K01796 - 5.1.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 545.0
HKD3_k127_1540377_9 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 499.0
HKD3_k127_1552141_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.9e-296 914.0
HKD3_k127_1552141_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 492.0
HKD3_k127_1552141_2 LysR substrate binding domain - - - 0.00001602 51.0
HKD3_k127_1603256_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.44e-264 828.0
HKD3_k127_1603256_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.997e-214 698.0
HKD3_k127_1603256_10 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 423.0
HKD3_k127_1603256_11 polar amino acid ABC transporter, inner membrane subunit K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 389.0
HKD3_k127_1603256_12 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 399.0
HKD3_k127_1603256_13 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000002175 204.0
HKD3_k127_1603256_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000001992 98.0
HKD3_k127_1603256_2 Drug resistance transporter Bcr CflA subfamily K07552 - - 1.294e-205 648.0
HKD3_k127_1603256_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.17e-202 667.0
HKD3_k127_1603256_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 631.0
HKD3_k127_1603256_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 580.0
HKD3_k127_1603256_6 Extracellular solute-binding protein family 3 K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 487.0
HKD3_k127_1603256_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 469.0
HKD3_k127_1603256_8 PFAM ABC transporter K10004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005032 449.0
HKD3_k127_1603256_9 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 445.0
HKD3_k127_1604763_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1370.0
HKD3_k127_1604763_1 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0 1210.0
HKD3_k127_1604763_10 O-methyltransferase activity - - - 2.122e-239 771.0
HKD3_k127_1604763_11 Urate oxidase N-terminal - - - 1.628e-234 729.0
HKD3_k127_1604763_12 Permease family K02824 - - 3.485e-232 724.0
HKD3_k127_1604763_13 Rieske [2Fe-2S] domain - - - 2.376e-207 648.0
HKD3_k127_1604763_14 peptidase dimerisation domain protein - - - 1.251e-206 677.0
HKD3_k127_1604763_15 competence protein COMEC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 595.0
HKD3_k127_1604763_16 NMT1/THI5 like K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 568.0
HKD3_k127_1604763_17 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 565.0
HKD3_k127_1604763_18 PFAM Polysaccharide deacetylase K01452 - 3.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 543.0
HKD3_k127_1604763_19 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 503.0
HKD3_k127_1604763_2 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1071.0
HKD3_k127_1604763_20 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 490.0
HKD3_k127_1604763_21 urea ABC transporter, ATP-binding protein K11962 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 474.0
HKD3_k127_1604763_22 binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 437.0
HKD3_k127_1604763_23 AAA domain K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 434.0
HKD3_k127_1604763_24 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 418.0
HKD3_k127_1604763_25 urea ABC transporter, ATP-binding protein K11963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 408.0
HKD3_k127_1604763_26 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 416.0
HKD3_k127_1604763_27 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 345.0
HKD3_k127_1604763_28 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 355.0
HKD3_k127_1604763_29 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004548 267.0
HKD3_k127_1604763_3 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 3.826e-305 946.0
HKD3_k127_1604763_30 MafB19-like deaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003934 240.0
HKD3_k127_1604763_31 Domain of unknown function (DUF1854) - - - 0.000000000000000000000000000000000000000000000000000000000006021 214.0
HKD3_k127_1604763_32 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.000000000000000000000000000000000000000000000000008745 182.0
HKD3_k127_1604763_33 Protein of unknown function (DUF2721) - - - 0.000000000000000000000000000000000000000005376 159.0
HKD3_k127_1604763_34 - - - - 0.000000000000000000000000000000000004629 145.0
HKD3_k127_1604763_35 response to abiotic stimulus - - - 0.000000000000000000000000000000001879 132.0
HKD3_k127_1604763_36 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000000000005269 120.0
HKD3_k127_1604763_37 PFAM Cytochrome C - - - 0.0000000000000000000000000004315 117.0
HKD3_k127_1604763_38 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000007436 101.0
HKD3_k127_1604763_4 Belongs to the aldehyde dehydrogenase family K00141 - 1.2.1.28 8.524e-280 879.0
HKD3_k127_1604763_5 TonB dependent receptor K02014 - - 3.255e-257 811.0
HKD3_k127_1604763_6 - - - - 1.479e-255 841.0
HKD3_k127_1604763_7 PFAM Xanthine uracil vitamin C permease K03458 - - 1.749e-246 769.0
HKD3_k127_1604763_8 Amidohydrolase family K18456 - 3.5.4.32 3.924e-245 762.0
HKD3_k127_1604763_9 Glucose / Sorbosone dehydrogenase - - - 6.601e-243 755.0
HKD3_k127_1747298_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 1.271e-267 836.0
HKD3_k127_1747298_1 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.409e-226 715.0
HKD3_k127_1747298_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004892 362.0
HKD3_k127_1747298_11 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008073 281.0
HKD3_k127_1747298_12 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005343 267.0
HKD3_k127_1747298_13 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000000000004093 210.0
HKD3_k127_1747298_14 Translation initiation factor K03113 - - 0.0000000000000000000000000000000000000000001979 161.0
HKD3_k127_1747298_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 586.0
HKD3_k127_1747298_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005264 582.0
HKD3_k127_1747298_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 536.0
HKD3_k127_1747298_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 494.0
HKD3_k127_1747298_6 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 477.0
HKD3_k127_1747298_7 Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 390.0
HKD3_k127_1747298_8 Protein of unknown function (DUF455) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 376.0
HKD3_k127_1747298_9 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 347.0
HKD3_k127_1770103_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1276.0
HKD3_k127_1770103_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1002.0
HKD3_k127_1770103_10 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 370.0
HKD3_k127_1770103_11 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 353.0
HKD3_k127_1770103_12 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 310.0
HKD3_k127_1770103_13 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 297.0
HKD3_k127_1770103_14 Nicotinamide mononucleotide transporter K03811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 282.0
HKD3_k127_1770103_15 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002182 281.0
HKD3_k127_1770103_16 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006283 265.0
HKD3_k127_1770103_17 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004473 239.0
HKD3_k127_1770103_18 WHG domain - - - 0.00000000000000000000000000000000000000000000008625 176.0
HKD3_k127_1770103_19 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K09181,K15520 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0017076,GO:0030551,GO:0030552,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.3.1.189 0.0000000000000000000000000000000000000000001798 169.0
HKD3_k127_1770103_2 Serine aminopeptidase, S33 - - - 4.066e-299 940.0
HKD3_k127_1770103_20 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000003564 154.0
HKD3_k127_1770103_21 - - - - 0.0000000000000000000000000000000000004942 150.0
HKD3_k127_1770103_22 - - - - 0.000000000000000000000000000000000001293 154.0
HKD3_k127_1770103_23 Domain of unknown function (DUF4281) - - - 0.000000000000000000000000000000744 127.0
HKD3_k127_1770103_24 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000009454 117.0
HKD3_k127_1770103_25 - - - - 0.000000000000000000000000003726 124.0
HKD3_k127_1770103_26 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000002368 98.0
HKD3_k127_1770103_27 PFAM Outer membrane porin - - - 0.000000000008061 78.0
HKD3_k127_1770103_28 - - - - 0.0000000004253 73.0
HKD3_k127_1770103_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 1.029e-256 796.0
HKD3_k127_1770103_4 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 4.669e-240 754.0
HKD3_k127_1770103_5 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 1.395e-199 630.0
HKD3_k127_1770103_6 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 527.0
HKD3_k127_1770103_7 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 509.0
HKD3_k127_1770103_8 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 476.0
HKD3_k127_1770103_9 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 460.0
HKD3_k127_1772884_0 PBP superfamily domain K07219 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 484.0
HKD3_k127_1772884_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 398.0
HKD3_k127_1772884_2 protein deglycation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 351.0
HKD3_k127_1772884_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 351.0
HKD3_k127_1772884_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 304.0
HKD3_k127_1772884_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002414 283.0
HKD3_k127_1772884_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000007471 222.0
HKD3_k127_1772884_7 Antibiotic biosynthesis monooxygenase K09932 - - 0.000000000000000000000000000000000000000000000000000007631 196.0
HKD3_k127_1772884_8 COGs COG4935 Regulatory P domain of the subtilisin-like proprotein convertase and other protease K13735,K20276,K20755,K21449 - 3.4.21.121 0.0000000000000002856 86.0
HKD3_k127_1800689_0 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 421.0
HKD3_k127_1800689_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 406.0
HKD3_k127_1800689_2 COG0671 Membrane-associated phospholipid phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 329.0
HKD3_k127_1800689_3 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000009785 146.0
HKD3_k127_1800689_4 Peptidase M48 Ste24p - - - 0.0000000000174 64.0
HKD3_k127_1815991_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0 1090.0
HKD3_k127_1815991_1 VWA domain containing CoxE-like protein K09989 - - 8.801e-230 718.0
HKD3_k127_1815991_2 surface antigen K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 583.0
HKD3_k127_1815991_3 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 510.0
HKD3_k127_1815991_4 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 376.0
HKD3_k127_1815991_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 319.0
HKD3_k127_1815991_6 acetyltransferase - - - 0.0000000000000000000000001572 118.0
HKD3_k127_1815991_7 Cytochrome c class I - - - 0.00000000000000000003294 93.0
HKD3_k127_1815991_8 - - - - 0.00002581 57.0
HKD3_k127_1838097_0 acyl-CoA dehydrogenase - - - 1.5e-323 999.0
HKD3_k127_1838097_1 Methionine synthase K00549 - 2.1.1.14 1.88e-205 668.0
HKD3_k127_1838097_10 outer membrane lipoprotein K06077 - - 0.0000000000000000000000000000000000000000000017 172.0
HKD3_k127_1838097_2 CoA-transferase family III - - - 4.199e-199 627.0
HKD3_k127_1838097_3 Rieske [2Fe-2S] domain K03862,K18068 - 1.14.12.7,1.14.13.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 591.0
HKD3_k127_1838097_4 oxidoreductase FAD NAD(P)-binding domain protein K03863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 507.0
HKD3_k127_1838097_5 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009653 419.0
HKD3_k127_1838097_6 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 364.0
HKD3_k127_1838097_7 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 346.0
HKD3_k127_1838097_8 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 336.0
HKD3_k127_1838097_9 Regulatory protein GntR HTH K11475 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001652 286.0
HKD3_k127_1921730_0 FAD linked oxidase domain protein - - - 0.0 2240.0
HKD3_k127_1921730_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1456.0
HKD3_k127_1921730_10 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 524.0
HKD3_k127_1921730_11 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 424.0
HKD3_k127_1921730_12 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 415.0
HKD3_k127_1921730_13 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 405.0
HKD3_k127_1921730_14 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005946 342.0
HKD3_k127_1921730_15 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007908 312.0
HKD3_k127_1921730_16 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003414 243.0
HKD3_k127_1921730_17 PPIC-type PPIASE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008342 254.0
HKD3_k127_1921730_18 protein conserved in bacteria K03690 - - 0.000000000000000000000000000000000000000000000000000000000006009 220.0
HKD3_k127_1921730_19 HIT domain - - - 0.00000000000000000000000000000000000000002979 177.0
HKD3_k127_1921730_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.666e-304 951.0
HKD3_k127_1921730_20 Regulatory protein, FmdB family - - - 0.000000000000000000000000000000000000575 143.0
HKD3_k127_1921730_21 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000003981 117.0
HKD3_k127_1921730_22 - - - - 0.00000000001172 72.0
HKD3_k127_1921730_23 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000748 52.0
HKD3_k127_1921730_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.908e-268 845.0
HKD3_k127_1921730_4 LPXTG-motif cell wall anchor domain - - - 2.122e-267 857.0
HKD3_k127_1921730_5 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 1.707e-216 681.0
HKD3_k127_1921730_6 PFAM extracellular solute-binding protein family 1 K02027,K05813 - - 3.831e-214 672.0
HKD3_k127_1921730_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 5.187e-202 635.0
HKD3_k127_1921730_8 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 574.0
HKD3_k127_1921730_9 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 557.0
HKD3_k127_198883_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1606.0
HKD3_k127_198883_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.468e-284 878.0
HKD3_k127_198883_10 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 338.0
HKD3_k127_198883_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.784e-218 683.0
HKD3_k127_198883_3 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 493.0
HKD3_k127_198883_4 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 441.0
HKD3_k127_198883_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 438.0
HKD3_k127_198883_6 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 432.0
HKD3_k127_198883_7 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 423.0
HKD3_k127_198883_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007962 381.0
HKD3_k127_198883_9 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 372.0
HKD3_k127_2098756_0 PFAM ResB family protein K07399 - - 1.541e-290 909.0
HKD3_k127_2098756_1 Cytochrome C assembly protein - - - 2.481e-234 730.0
HKD3_k127_2098756_10 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 334.0
HKD3_k127_2098756_11 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 305.0
HKD3_k127_2098756_12 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 302.0
HKD3_k127_2098756_13 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001007 247.0
HKD3_k127_2098756_14 Kelch - - - 0.00000000000000000000000000000000000000000000000000006299 206.0
HKD3_k127_2098756_15 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000319 191.0
HKD3_k127_2098756_16 Transcriptional regulator - - - 0.0000000000000000000000000000000001352 141.0
HKD3_k127_2098756_2 DctM subunit - - - 3.179e-201 635.0
HKD3_k127_2098756_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 539.0
HKD3_k127_2098756_4 PFAM Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 550.0
HKD3_k127_2098756_5 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 489.0
HKD3_k127_2098756_6 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 434.0
HKD3_k127_2098756_7 SMP-30 Gluconolaconase LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 412.0
HKD3_k127_2098756_8 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 408.0
HKD3_k127_2098756_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 394.0
HKD3_k127_2244558_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.355e-239 753.0
HKD3_k127_2244558_1 FAD linked oxidases, C-terminal domain - - - 3.596e-217 689.0
HKD3_k127_2244558_2 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 445.0
HKD3_k127_2244558_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 345.0
HKD3_k127_2244558_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 300.0
HKD3_k127_2244558_5 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000003746 233.0
HKD3_k127_2244558_6 Predicted membrane protein (DUF2069) - - - 0.0000000000000000000000000000000000000521 154.0
HKD3_k127_2244558_7 sequence-specific DNA binding K07726 - - 0.000000000000000000000000000003549 122.0
HKD3_k127_2270859_0 PFAM carboxyl transferase K01969 - 6.4.1.4 3.017e-312 960.0
HKD3_k127_2270859_1 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 531.0
HKD3_k127_2270859_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 454.0
HKD3_k127_2270859_3 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 463.0
HKD3_k127_2270859_4 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006099 318.0
HKD3_k127_2270859_5 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 313.0
HKD3_k127_2270859_6 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000006339 190.0
HKD3_k127_2270859_7 membrane - - - 0.000000000000000000000000000000000000000000000000001714 200.0
HKD3_k127_2270859_8 - - - - 0.000000000000000000000000000299 124.0
HKD3_k127_240247_0 metal-dependent hydrolase with the TIM-barrel fold - - - 1.102e-220 692.0
HKD3_k127_240247_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 392.0
HKD3_k127_240247_2 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 352.0
HKD3_k127_240247_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006068 284.0
HKD3_k127_240247_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000004564 179.0
HKD3_k127_240247_5 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000008628 189.0
HKD3_k127_240247_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000003021 158.0
HKD3_k127_240247_7 Short-chain dehydrogenase reductase (SDR) - - - 0.000000000000000000000000000000000006099 139.0
HKD3_k127_2435411_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.634e-261 838.0
HKD3_k127_2435411_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.034e-219 694.0
HKD3_k127_2435411_10 PIN domain - - - 0.0000000000000000000000000000000000000000000000000004025 187.0
HKD3_k127_2435411_11 Pyridoxamine 5'-phosphate oxidase K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000001236 183.0
HKD3_k127_2435411_12 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000005721 79.0
HKD3_k127_2435411_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 630.0
HKD3_k127_2435411_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 393.0
HKD3_k127_2435411_4 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 376.0
HKD3_k127_2435411_5 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006005 350.0
HKD3_k127_2435411_6 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 290.0
HKD3_k127_2435411_7 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 296.0
HKD3_k127_2435411_8 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 298.0
HKD3_k127_2435411_9 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000000001728 242.0
HKD3_k127_2452504_0 Serine aminopeptidase, S33 - - - 8.773e-203 643.0
HKD3_k127_2452504_1 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 567.0
HKD3_k127_2452504_2 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 526.0
HKD3_k127_2452504_3 Protein of unknown function (DUF1254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 388.0
HKD3_k127_2452504_4 Protein of unknown function (DUF1254) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004233 263.0
HKD3_k127_2452504_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000003108 119.0
HKD3_k127_2452504_6 - - - - 0.000000000000000001022 90.0
HKD3_k127_2461203_0 Alanine dehydrogenase/PNT, C-terminal domain K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 483.0
HKD3_k127_2461203_1 Transcriptional regulator K13635 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 450.0
HKD3_k127_2461203_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 GO:0003674,GO:0003824,GO:0004362,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006091,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0015036,GO:0015037,GO:0015038,GO:0015949,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0022900,GO:0031974,GO:0033554,GO:0034599,GO:0034641,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0055114,GO:0070013,GO:0070887,GO:0071704,GO:0097237,GO:0098754,GO:0098869,GO:1901360,GO:1990748 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 429.0
HKD3_k127_2461203_3 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 316.0
HKD3_k127_2461203_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000001521 211.0
HKD3_k127_247076_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1067.0
HKD3_k127_247076_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1021.0
HKD3_k127_247076_10 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 434.0
HKD3_k127_247076_11 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000718 409.0
HKD3_k127_247076_12 Zinc iron permease K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 385.0
HKD3_k127_247076_13 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 352.0
HKD3_k127_247076_14 2-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001021 298.0
HKD3_k127_247076_15 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002577 251.0
HKD3_k127_247076_16 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003346 244.0
HKD3_k127_247076_17 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003782 239.0
HKD3_k127_247076_18 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000006998 228.0
HKD3_k127_247076_19 Phosphoglycerate mutase family K08296 - - 0.0000000000000000000000000000000000000000000000000000000009216 207.0
HKD3_k127_247076_2 General secretory system II, protein E domain protein K02454,K02652 - - 2.89e-287 905.0
HKD3_k127_247076_20 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000004319 205.0
HKD3_k127_247076_21 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000009424 192.0
HKD3_k127_247076_22 General secretory system II, protein E domain protein K02454 - - 0.0000000000000000000000000000000000000000000001943 183.0
HKD3_k127_247076_23 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000006164 101.0
HKD3_k127_247076_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 5.442e-217 679.0
HKD3_k127_247076_4 Rieske 2Fe-2S K00499 - 1.14.15.7 8.503e-214 667.0
HKD3_k127_247076_5 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 1.423e-212 671.0
HKD3_k127_247076_6 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009371 576.0
HKD3_k127_247076_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 569.0
HKD3_k127_247076_8 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 438.0
HKD3_k127_247076_9 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 433.0
HKD3_k127_2510519_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.724e-316 980.0
HKD3_k127_2510519_1 Tripartite tricarboxylate transporter TctA family K07793 - - 1.558e-256 797.0
HKD3_k127_2510519_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000002276 237.0
HKD3_k127_2510519_11 Tripartite tricarboxylate transporter TctB family K07794 - - 0.000000000000000000000000000000000000000000000000000000003995 206.0
HKD3_k127_2510519_12 PFAM RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000000000000000000000005904 178.0
HKD3_k127_2510519_13 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.17.1.8 0.0000000000001123 83.0
HKD3_k127_2510519_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 3.123e-217 711.0
HKD3_k127_2510519_3 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006737 593.0
HKD3_k127_2510519_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 572.0
HKD3_k127_2510519_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009157 543.0
HKD3_k127_2510519_6 PFAM conserved K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 517.0
HKD3_k127_2510519_7 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 398.0
HKD3_k127_2510519_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 388.0
HKD3_k127_2510519_9 Transcriptional regulatory protein, C terminal K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 332.0
HKD3_k127_2543565_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 7.449e-234 751.0
HKD3_k127_2543565_1 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 349.0
HKD3_k127_2543565_2 Flavodoxin-like fold K00355,K11746,K11748 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001185 271.0
HKD3_k127_2543565_3 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000008643 136.0
HKD3_k127_2547511_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 4.256e-250 781.0
HKD3_k127_2547511_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.042e-241 748.0
HKD3_k127_2547511_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 487.0
HKD3_k127_2547511_11 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 411.0
HKD3_k127_2547511_12 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 383.0
HKD3_k127_2547511_13 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 286.0
HKD3_k127_2547511_14 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001211 268.0
HKD3_k127_2547511_15 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000263 284.0
HKD3_k127_2547511_16 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000001048 221.0
HKD3_k127_2547511_17 - - - - 0.00000000000000000001877 91.0
HKD3_k127_2547511_18 - - - - 0.00000008053 63.0
HKD3_k127_2547511_2 Amidohydrolase family - - - 3.964e-210 662.0
HKD3_k127_2547511_3 Flavin-binding monooxygenase-like - - - 6.392e-206 650.0
HKD3_k127_2547511_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1.197e-200 632.0
HKD3_k127_2547511_5 PFAM FAD linked oxidase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 573.0
HKD3_k127_2547511_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 544.0
HKD3_k127_2547511_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 523.0
HKD3_k127_2547511_8 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 517.0
HKD3_k127_2547511_9 Belongs to the glycosyl hydrolase 13 family K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 463.0
HKD3_k127_2575356_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1099.0
HKD3_k127_2575356_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02454,K02504,K02652 - - 4.656e-253 793.0
HKD3_k127_2575356_10 peptidase M48, Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 455.0
HKD3_k127_2575356_11 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 424.0
HKD3_k127_2575356_12 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008564 448.0
HKD3_k127_2575356_13 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 425.0
HKD3_k127_2575356_14 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 388.0
HKD3_k127_2575356_15 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 379.0
HKD3_k127_2575356_16 Bacterial transcriptional repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000722 373.0
HKD3_k127_2575356_17 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 358.0
HKD3_k127_2575356_18 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000007208 280.0
HKD3_k127_2575356_19 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003351 258.0
HKD3_k127_2575356_2 Protein of unknown function (DUF1298) - - - 1.217e-223 704.0
HKD3_k127_2575356_20 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000000000000008073 194.0
HKD3_k127_2575356_21 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000000000004254 143.0
HKD3_k127_2575356_22 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.000000000000000000000000000000000000774 148.0
HKD3_k127_2575356_23 acyl-coA-binding protein - - - 0.00000000000000000000000000000000002495 139.0
HKD3_k127_2575356_24 - - - - 0.0000000000000000000000000007788 130.0
HKD3_k127_2575356_25 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000000007751 87.0
HKD3_k127_2575356_3 Peptidase dimerisation domain K01451 - 3.5.1.32 1.592e-219 696.0
HKD3_k127_2575356_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.253e-214 671.0
HKD3_k127_2575356_5 Type II secretion system K02653 - - 1.701e-213 670.0
HKD3_k127_2575356_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 601.0
HKD3_k127_2575356_7 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 537.0
HKD3_k127_2575356_8 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 519.0
HKD3_k127_2575356_9 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 506.0
HKD3_k127_26393_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 1.112e-309 956.0
HKD3_k127_26393_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 464.0
HKD3_k127_26393_2 MltA-interacting protein MipA K07274 - - 0.00000000000000000000000000000000000000000000000008765 192.0
HKD3_k127_2639306_0 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1098.0
HKD3_k127_2639306_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.884e-319 992.0
HKD3_k127_2639306_10 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 616.0
HKD3_k127_2639306_11 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 571.0
HKD3_k127_2639306_12 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 538.0
HKD3_k127_2639306_13 leucyl aminopeptidase, aminopeptidase T K18028 - 1.13.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 524.0
HKD3_k127_2639306_14 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 493.0
HKD3_k127_2639306_15 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 475.0
HKD3_k127_2639306_16 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 477.0
HKD3_k127_2639306_17 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004185 436.0
HKD3_k127_2639306_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 425.0
HKD3_k127_2639306_19 Uncharacterized protein conserved in bacteria (DUF2331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 400.0
HKD3_k127_2639306_2 Large family of predicted nucleotide-binding domains K07175 - - 5.317e-299 924.0
HKD3_k127_2639306_20 Protein of unknown function (DUF3445) K22342 - 1.14.13.238 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
HKD3_k127_2639306_21 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 341.0
HKD3_k127_2639306_22 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 339.0
HKD3_k127_2639306_23 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 326.0
HKD3_k127_2639306_24 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 295.0
HKD3_k127_2639306_25 Phospholipase/Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 292.0
HKD3_k127_2639306_26 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003107 266.0
HKD3_k127_2639306_27 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002625 276.0
HKD3_k127_2639306_28 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.000000000000000000000000000000000000000000000000000000000026 210.0
HKD3_k127_2639306_29 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000003275 233.0
HKD3_k127_2639306_3 PFAM Aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 2.305e-249 772.0
HKD3_k127_2639306_30 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000169 207.0
HKD3_k127_2639306_31 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000002326 184.0
HKD3_k127_2639306_32 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000003706 178.0
HKD3_k127_2639306_33 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000003508 171.0
HKD3_k127_2639306_34 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000009487 153.0
HKD3_k127_2639306_35 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000001263 171.0
HKD3_k127_2639306_36 PFAM thioesterase superfamily protein K01075 - 3.1.2.23 0.0000000000000000000000000000000007184 150.0
HKD3_k127_2639306_37 - - - - 0.00000000000000000000000000004406 120.0
HKD3_k127_2639306_38 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000000001249 119.0
HKD3_k127_2639306_39 Protein of unknown function (DUF2846) - - - 0.0000000000000000000000317 110.0
HKD3_k127_2639306_4 Threonine synthase K01733 - 4.2.3.1 1.398e-246 787.0
HKD3_k127_2639306_5 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 7.11e-245 766.0
HKD3_k127_2639306_6 homoserine dehydrogenase K00003 - 1.1.1.3 2.097e-240 749.0
HKD3_k127_2639306_7 peptidylprolyl isomerase K03770 - 5.2.1.8 6.48e-217 692.0
HKD3_k127_2639306_8 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 9.559e-208 665.0
HKD3_k127_2639306_9 PFAM isocitrate isopropylmalate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 1.549e-199 625.0
HKD3_k127_2689842_0 Belongs to the GPI family K01810 - 5.3.1.9 6.82e-268 849.0
HKD3_k127_2689842_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 5.626e-254 789.0
HKD3_k127_2689842_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 4.367e-249 778.0
HKD3_k127_2689842_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002581 422.0
HKD3_k127_2689842_4 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000000000000000000003282 192.0
HKD3_k127_2689842_5 - - - - 0.000000000000000000000000000002764 138.0
HKD3_k127_2752089_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 1.63e-322 1019.0
HKD3_k127_2752089_1 5'-nucleotidase, C-terminal domain K11751,K17224 - 3.1.3.5,3.6.1.45 2.913e-311 960.0
HKD3_k127_2752089_10 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 420.0
HKD3_k127_2752089_11 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 376.0
HKD3_k127_2752089_12 EamA-like transporter family K15269 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 376.0
HKD3_k127_2752089_13 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 364.0
HKD3_k127_2752089_14 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005692 282.0
HKD3_k127_2752089_15 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003422 262.0
HKD3_k127_2752089_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002459 261.0
HKD3_k127_2752089_17 Alkyl hydroperoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008149 254.0
HKD3_k127_2752089_18 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000000000000006744 251.0
HKD3_k127_2752089_19 protein domain associated with - - - 0.0000000000000000000000000000000000000000000000000000000000000000001546 244.0
HKD3_k127_2752089_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 6.537e-308 947.0
HKD3_k127_2752089_20 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000008296 229.0
HKD3_k127_2752089_21 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000000000000000002239 198.0
HKD3_k127_2752089_22 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000005855 194.0
HKD3_k127_2752089_23 oxidation protein K17227 - - 0.0000000000000000000000000000000000000000000000006852 176.0
HKD3_k127_2752089_24 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000001503 177.0
HKD3_k127_2752089_25 Transcriptional regulator - - - 0.000000000000000000000000000000005181 133.0
HKD3_k127_2752089_26 Late competence development protein ComFB - - - 0.000000000000000000000002627 108.0
HKD3_k127_2752089_27 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000006674 112.0
HKD3_k127_2752089_28 Cytochrome c - - - 0.000000000000000000003485 97.0
HKD3_k127_2752089_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.941e-292 912.0
HKD3_k127_2752089_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.292e-279 891.0
HKD3_k127_2752089_5 Mo-co oxidoreductase dimerisation domain K17225 - - 4.444e-229 715.0
HKD3_k127_2752089_6 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 2.436e-197 628.0
HKD3_k127_2752089_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007488 614.0
HKD3_k127_2752089_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 562.0
HKD3_k127_2752089_9 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 432.0
HKD3_k127_2764973_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 4.217e-266 826.0
HKD3_k127_2764973_1 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 580.0
HKD3_k127_2764973_10 SMART Rhodanese domain protein - - - 0.0000000000000000000000002797 109.0
HKD3_k127_2764973_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 539.0
HKD3_k127_2764973_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 518.0
HKD3_k127_2764973_4 MCRA family K10254 - 4.2.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 492.0
HKD3_k127_2764973_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008187 460.0
HKD3_k127_2764973_6 C4-dicarboxylate transporter malic acid transport protein K03304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 426.0
HKD3_k127_2764973_7 RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 400.0
HKD3_k127_2764973_8 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 374.0
HKD3_k127_2764973_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001489 275.0
HKD3_k127_2856453_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1505.0
HKD3_k127_2856453_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1340.0
HKD3_k127_2856453_10 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 520.0
HKD3_k127_2856453_11 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 490.0
HKD3_k127_2856453_12 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 452.0
HKD3_k127_2856453_13 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 443.0
HKD3_k127_2856453_14 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 435.0
HKD3_k127_2856453_15 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 416.0
HKD3_k127_2856453_16 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 377.0
HKD3_k127_2856453_17 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 372.0
HKD3_k127_2856453_18 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 361.0
HKD3_k127_2856453_19 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 329.0
HKD3_k127_2856453_2 Protein of unknown function - - - 0.0 1158.0
HKD3_k127_2856453_20 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 313.0
HKD3_k127_2856453_21 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003512 315.0
HKD3_k127_2856453_22 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 299.0
HKD3_k127_2856453_23 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 285.0
HKD3_k127_2856453_24 short-chain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007916 284.0
HKD3_k127_2856453_25 Ankyrin repeats (3 copies) K06867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003428 287.0
HKD3_k127_2856453_26 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000002545 269.0
HKD3_k127_2856453_27 Protein of unknown function (DUF3833) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003974 274.0
HKD3_k127_2856453_28 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008907 247.0
HKD3_k127_2856453_29 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000009463 242.0
HKD3_k127_2856453_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.05e-252 784.0
HKD3_k127_2856453_30 oxidoreductase K06955 - - 0.000000000000000000000000000000000000000000000000000000000000000002699 245.0
HKD3_k127_2856453_31 SnoaL-like domain K01822 - 5.3.3.1 0.000000000000000000000000000000000000000000000000000000000008192 222.0
HKD3_k127_2856453_32 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000000000000000000000002533 218.0
HKD3_k127_2856453_33 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.0000000000000000000000000000000000000000000000000000001045 199.0
HKD3_k127_2856453_34 Rhomboid family - - - 0.0000000000000000000000000000000000000000000003715 193.0
HKD3_k127_2856453_35 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.0000000000000000000000000000000000000000000006245 175.0
HKD3_k127_2856453_36 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000008372 183.0
HKD3_k127_2856453_37 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000000000000000000000000001749 172.0
HKD3_k127_2856453_38 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000002779 142.0
HKD3_k127_2856453_39 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000001891 129.0
HKD3_k127_2856453_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 5.378e-201 632.0
HKD3_k127_2856453_40 Dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000001385 99.0
HKD3_k127_2856453_41 Protein of unknown function (DUF2905) - - - 0.0000000000000000001353 91.0
HKD3_k127_2856453_5 Flavin containing amine oxidoreductase K06954 - - 3.69e-200 631.0
HKD3_k127_2856453_6 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 561.0
HKD3_k127_2856453_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 531.0
HKD3_k127_2856453_8 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 529.0
HKD3_k127_2856453_9 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 513.0
HKD3_k127_2872304_0 Signal transducing histidine kinase, homodimeric domain K02487,K06596 - - 0.0 1816.0
HKD3_k127_2872304_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1578.0
HKD3_k127_2872304_10 Patatin-like phospholipase - - - 9.683e-229 724.0
HKD3_k127_2872304_11 Aminotransferase K01845 - 5.4.3.8 3.273e-227 717.0
HKD3_k127_2872304_12 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.556e-209 672.0
HKD3_k127_2872304_13 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 530.0
HKD3_k127_2872304_14 Type IV pili methyl-accepting chemotaxis transducer N-term K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 533.0
HKD3_k127_2872304_15 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 524.0
HKD3_k127_2872304_16 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 469.0
HKD3_k127_2872304_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 462.0
HKD3_k127_2872304_18 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 465.0
HKD3_k127_2872304_19 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006015 472.0
HKD3_k127_2872304_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 2.09e-321 994.0
HKD3_k127_2872304_20 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 430.0
HKD3_k127_2872304_21 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 361.0
HKD3_k127_2872304_22 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 349.0
HKD3_k127_2872304_23 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 325.0
HKD3_k127_2872304_24 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 309.0
HKD3_k127_2872304_25 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001273 281.0
HKD3_k127_2872304_26 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003043 265.0
HKD3_k127_2872304_27 response regulator, receiver K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000003753 230.0
HKD3_k127_2872304_28 - - - - 0.000000000000000000000000000000000000000000000000000000000009254 211.0
HKD3_k127_2872304_29 PFAM response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000000000002235 214.0
HKD3_k127_2872304_3 Male sterility protein - - - 9.359e-312 967.0
HKD3_k127_2872304_30 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000002238 201.0
HKD3_k127_2872304_31 Bacterial protein of unknown function (DUF924) - - - 0.000000000000000000000000000000000000000000000000000002645 210.0
HKD3_k127_2872304_32 CheW-like domain K02659 - - 0.000000000000000000000000000000000000000000000000000007826 194.0
HKD3_k127_2872304_33 - - - - 0.00000000000000000000000000000000000000000001668 165.0
HKD3_k127_2872304_34 PGAP1-like protein - - - 0.0000000000000000000000000000000000000007498 160.0
HKD3_k127_2872304_35 rubredoxin - - - 0.000000000000000000000000000000008784 127.0
HKD3_k127_2872304_36 Protein of unknown function (DUF3297) - - - 0.000000000000000000000000005673 128.0
HKD3_k127_2872304_37 PFAM poly granule associated family protein - - - 0.000000000000000000000002477 106.0
HKD3_k127_2872304_38 Protein of unknown function (DUF2905) - - - 0.0000000000000000000004723 104.0
HKD3_k127_2872304_39 ABC-type dipeptide transport system, periplasmic component - - - 0.00000007591 57.0
HKD3_k127_2872304_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 1.23e-291 931.0
HKD3_k127_2872304_5 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 1.406e-289 915.0
HKD3_k127_2872304_6 Domain of unknown function (DUF5117) - - - 6.403e-273 871.0
HKD3_k127_2872304_7 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 2.799e-253 785.0
HKD3_k127_2872304_8 DNA photolyase K01669 - 4.1.99.3 2.721e-245 768.0
HKD3_k127_2872304_9 ABC-type dipeptide transport system, periplasmic component - - - 1.01e-243 766.0
HKD3_k127_2893246_0 PFAM AMP-dependent synthetase and ligase K12508 - 6.2.1.34 2.492e-313 971.0
HKD3_k127_2893246_1 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 1.346e-197 621.0
HKD3_k127_2893246_10 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 424.0
HKD3_k127_2893246_11 Belongs to the enoyl-CoA hydratase isomerase family K20036 - 4.2.1.155 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 395.0
HKD3_k127_2893246_12 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 352.0
HKD3_k127_2893246_13 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 350.0
HKD3_k127_2893246_14 PFAM ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 336.0
HKD3_k127_2893246_15 phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
HKD3_k127_2893246_16 Pilus assembly protein PilX - - - 0.0000000000000000000000000000000000000000000000000000000000000000001076 247.0
HKD3_k127_2893246_17 type IV pilus modification protein PilV - - - 0.000000000000000000000000000000000000000000000000105 195.0
HKD3_k127_2893246_18 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000002414 172.0
HKD3_k127_2893246_19 General secretion pathway protein K02672 - - 0.0000000000000000000000000000000000001866 151.0
HKD3_k127_2893246_2 Diguanylate cyclase - - - 4.709e-197 660.0
HKD3_k127_2893246_20 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000000252 122.0
HKD3_k127_2893246_21 ABC transporter K09810 - - 0.000000000000000000000000001651 112.0
HKD3_k127_2893246_22 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000003147 127.0
HKD3_k127_2893246_23 Domain of unknown function (DUF1840) - - - 0.000000000000000000000000212 113.0
HKD3_k127_2893246_24 Type II transport protein GspH K08084 - - 0.000000000001072 76.0
HKD3_k127_2893246_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 558.0
HKD3_k127_2893246_4 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007707 524.0
HKD3_k127_2893246_5 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 489.0
HKD3_k127_2893246_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 486.0
HKD3_k127_2893246_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 465.0
HKD3_k127_2893246_8 PFAM fumarylacetoacetate (FAA) hydrolase K16856,K18336 - 4.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 458.0
HKD3_k127_2893246_9 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 450.0
HKD3_k127_2896850_0 Sulfate permease family K03321 - - 5.875e-234 740.0
HKD3_k127_2896850_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 2.024e-213 691.0
HKD3_k127_2896850_2 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 495.0
HKD3_k127_2896850_3 4Fe-4S binding domain K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 464.0
HKD3_k127_2896850_4 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 412.0
HKD3_k127_2896850_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 355.0
HKD3_k127_2896850_6 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 314.0
HKD3_k127_2896850_7 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 342.0
HKD3_k127_2972625_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 2151.0
HKD3_k127_2972625_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1291.0
HKD3_k127_2972625_10 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 547.0
HKD3_k127_2972625_11 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 541.0
HKD3_k127_2972625_12 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 549.0
HKD3_k127_2972625_13 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 528.0
HKD3_k127_2972625_14 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 527.0
HKD3_k127_2972625_15 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 477.0
HKD3_k127_2972625_16 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 478.0
HKD3_k127_2972625_17 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 484.0
HKD3_k127_2972625_18 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 462.0
HKD3_k127_2972625_19 HflC and HflK could regulate a protease K04087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 461.0
HKD3_k127_2972625_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1142.0
HKD3_k127_2972625_20 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 440.0
HKD3_k127_2972625_21 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 436.0
HKD3_k127_2972625_22 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009635 437.0
HKD3_k127_2972625_23 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 419.0
HKD3_k127_2972625_24 Udp N-acetylglucosamine O-acyltransferase; Domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 414.0
HKD3_k127_2972625_25 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 374.0
HKD3_k127_2972625_26 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 369.0
HKD3_k127_2972625_27 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 353.0
HKD3_k127_2972625_28 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004604 338.0
HKD3_k127_2972625_29 Predicted integral membrane protein (DUF2189) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 319.0
HKD3_k127_2972625_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1107.0
HKD3_k127_2972625_30 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 324.0
HKD3_k127_2972625_31 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 304.0
HKD3_k127_2972625_32 rRNA methyltransferase K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
HKD3_k127_2972625_33 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 289.0
HKD3_k127_2972625_34 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 290.0
HKD3_k127_2972625_35 Polyhydroxyalkanoate synthesis repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
HKD3_k127_2972625_36 Belongs to the skp family K06142 - - 0.00000000000000000000000000000000000000000000000000000000000001418 219.0
HKD3_k127_2972625_37 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000004165 220.0
HKD3_k127_2972625_38 membrane - - - 0.00000000000000000000000000000000000000000000141 185.0
HKD3_k127_2972625_39 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000000009801 161.0
HKD3_k127_2972625_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.491e-252 784.0
HKD3_k127_2972625_40 Protein of unknown function (DUF2788) - - - 0.00000000000000000000000000004064 117.0
HKD3_k127_2972625_41 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000000002428 85.0
HKD3_k127_2972625_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 6.782e-203 643.0
HKD3_k127_2972625_6 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 4.708e-200 644.0
HKD3_k127_2972625_7 RmuC family K09760 - - 2.138e-195 621.0
HKD3_k127_2972625_8 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 594.0
HKD3_k127_2972625_9 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 569.0
HKD3_k127_2981140_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1548.0
HKD3_k127_2981140_1 Protein of unknown function (DUF3141) - - - 1.387e-281 897.0
HKD3_k127_2981140_10 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 459.0
HKD3_k127_2981140_11 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 466.0
HKD3_k127_2981140_12 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 416.0
HKD3_k127_2981140_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 355.0
HKD3_k127_2981140_14 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 344.0
HKD3_k127_2981140_15 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 327.0
HKD3_k127_2981140_16 Transcriptional regulator K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 329.0
HKD3_k127_2981140_17 Methyltransferase type 11 K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 314.0
HKD3_k127_2981140_18 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 309.0
HKD3_k127_2981140_19 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007797 295.0
HKD3_k127_2981140_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.427e-260 809.0
HKD3_k127_2981140_20 ABC transporter (permease) K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002978 262.0
HKD3_k127_2981140_21 Bacterial transcriptional repressor C-terminal K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001679 269.0
HKD3_k127_2981140_22 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000004502 207.0
HKD3_k127_2981140_23 Water Stress and Hypersensitive response - - - 0.000000000000000000000000000000000000000002924 162.0
HKD3_k127_2981140_24 cytochrome - - - 0.0000000000000000000000000000001359 127.0
HKD3_k127_2981140_26 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000003752 49.0
HKD3_k127_2981140_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 4.28e-249 776.0
HKD3_k127_2981140_4 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 4.506e-216 676.0
HKD3_k127_2981140_5 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 7.077e-214 667.0
HKD3_k127_2981140_6 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 561.0
HKD3_k127_2981140_7 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 526.0
HKD3_k127_2981140_8 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 499.0
HKD3_k127_2981140_9 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000548 452.0
HKD3_k127_3002113_0 type II secretion system protein E K02454,K02652 - - 4.953e-287 908.0
HKD3_k127_3002113_1 Tripartite tricarboxylate transporter TctA family K07793 - - 2.081e-282 872.0
HKD3_k127_3002113_10 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 479.0
HKD3_k127_3002113_11 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 474.0
HKD3_k127_3002113_12 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 392.0
HKD3_k127_3002113_13 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 367.0
HKD3_k127_3002113_14 Spermidine synthase K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 364.0
HKD3_k127_3002113_15 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 346.0
HKD3_k127_3002113_16 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004388 331.0
HKD3_k127_3002113_17 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 323.0
HKD3_k127_3002113_18 peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 320.0
HKD3_k127_3002113_19 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004101 234.0
HKD3_k127_3002113_2 chemotaxis sensory transducer K03406,K03776,K05874 - - 3.924e-280 887.0
HKD3_k127_3002113_20 SMART CheW domain protein K03408 - - 0.000000000000000000000000000000000000000000000001172 178.0
HKD3_k127_3002113_21 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000002265 166.0
HKD3_k127_3002113_22 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000001713 163.0
HKD3_k127_3002113_23 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000008329 134.0
HKD3_k127_3002113_3 PFAM phosphoesterase, RecJ domain protein K07462 - - 5.558e-263 840.0
HKD3_k127_3002113_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 5.836e-255 797.0
HKD3_k127_3002113_5 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 9.844e-213 666.0
HKD3_k127_3002113_6 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 1.777e-202 655.0
HKD3_k127_3002113_7 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 531.0
HKD3_k127_3002113_8 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 511.0
HKD3_k127_3002113_9 Von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 494.0
HKD3_k127_3120924_0 Peptidase M61 - - - 5.048e-229 728.0
HKD3_k127_3120924_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 3.172e-213 670.0
HKD3_k127_3120924_10 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000000000000000008874 194.0
HKD3_k127_3120924_11 Protein of unknown function (DUF3429) - - - 0.0000000000000000000000000000000002922 139.0
HKD3_k127_3120924_12 - - - - 0.00000000000000004332 89.0
HKD3_k127_3120924_2 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 426.0
HKD3_k127_3120924_3 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 421.0
HKD3_k127_3120924_4 Pirin C-terminal cupin domain K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 398.0
HKD3_k127_3120924_5 MOSC N-terminal beta barrel domain K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 385.0
HKD3_k127_3120924_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 317.0
HKD3_k127_3120924_7 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001555 310.0
HKD3_k127_3120924_8 DNA-sulfur modification-associated K19169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005019 267.0
HKD3_k127_3120924_9 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000004351 181.0
HKD3_k127_3134278_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 2.014e-250 785.0
HKD3_k127_3134278_1 Transporter associated domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 528.0
HKD3_k127_3134278_2 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 539.0
HKD3_k127_3134278_3 helicase superfamily c-terminal domain K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 477.0
HKD3_k127_3134278_4 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 450.0
HKD3_k127_3134278_5 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 403.0
HKD3_k127_3134278_6 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 392.0
HKD3_k127_3134278_7 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003725 245.0
HKD3_k127_3134278_8 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000001834 156.0
HKD3_k127_3178969_0 TRAP dicarboxylate transporter, DctM subunit K03299 - - 4.272e-280 873.0
HKD3_k127_3178969_1 Polyhydroxyalkanoate depolymerase, intracellular K05973 - 3.1.1.75 2.788e-236 742.0
HKD3_k127_3178969_10 serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 441.0
HKD3_k127_3178969_11 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 400.0
HKD3_k127_3178969_12 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003236 370.0
HKD3_k127_3178969_13 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 364.0
HKD3_k127_3178969_14 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 342.0
HKD3_k127_3178969_15 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 334.0
HKD3_k127_3178969_16 molybdenum cofactor K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 319.0
HKD3_k127_3178969_17 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 332.0
HKD3_k127_3178969_18 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 303.0
HKD3_k127_3178969_19 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 284.0
HKD3_k127_3178969_2 peptidase U62, modulator of DNA gyrase K03592 - - 3.284e-230 722.0
HKD3_k127_3178969_20 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 304.0
HKD3_k127_3178969_21 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004169 304.0
HKD3_k127_3178969_22 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000003074 274.0
HKD3_k127_3178969_23 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000477 241.0
HKD3_k127_3178969_24 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000001239 207.0
HKD3_k127_3178969_25 Glycosyl transferase K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000001095 204.0
HKD3_k127_3178969_26 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000000000000002043 196.0
HKD3_k127_3178969_27 Putative phosphatase (DUF442) - - - 0.00000000000000000000000000000000000000000000008243 179.0
HKD3_k127_3178969_28 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000003407 176.0
HKD3_k127_3178969_29 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000000000001411 142.0
HKD3_k127_3178969_3 COG2366 Protein related to penicillin acylase K01434 - 3.5.1.11 4.952e-229 736.0
HKD3_k127_3178969_30 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000000000000000001635 134.0
HKD3_k127_3178969_31 Type II secretion system protein B K02451 - - 0.00000000000000000000001076 110.0
HKD3_k127_3178969_33 HNH endonuclease K07454 - - 0.0000000000000005907 86.0
HKD3_k127_3178969_34 - - - - 0.000000000000008289 89.0
HKD3_k127_3178969_4 PFAM Aminotransferase class I and II K00832 - 2.6.1.57 1.625e-208 655.0
HKD3_k127_3178969_5 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 587.0
HKD3_k127_3178969_6 outer membrane cobalamin receptor K02014,K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 609.0
HKD3_k127_3178969_7 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 526.0
HKD3_k127_3178969_8 AAA domain K02450,K12283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 533.0
HKD3_k127_3178969_9 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 522.0
HKD3_k127_3180256_0 Elongation factor G, domain IV K02355 - - 0.0 1142.0
HKD3_k127_3180256_1 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1107.0
HKD3_k127_3180256_10 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 313.0
HKD3_k127_3180256_11 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000138 252.0
HKD3_k127_3180256_12 - - - - 0.000000000000000000000000000000000000000000000000000000006398 209.0
HKD3_k127_3180256_13 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000002714 188.0
HKD3_k127_3180256_14 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000003545 183.0
HKD3_k127_3180256_15 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000000000002918 175.0
HKD3_k127_3180256_16 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000003443 158.0
HKD3_k127_3180256_17 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000004823 155.0
HKD3_k127_3180256_18 - - - - 0.0000000000000000000000000009404 121.0
HKD3_k127_3180256_19 GrpB protein - - - 0.000000000000000000000000002906 124.0
HKD3_k127_3180256_2 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 1.925e-219 689.0
HKD3_k127_3180256_3 Peptidase family S49 K04773 - - 5.702e-194 625.0
HKD3_k127_3180256_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 565.0
HKD3_k127_3180256_5 membrane protein TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008047 542.0
HKD3_k127_3180256_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 479.0
HKD3_k127_3180256_7 Response regulator of the LytR AlgR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 403.0
HKD3_k127_3180256_8 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 377.0
HKD3_k127_3180256_9 Aldo keto K00011 - 1.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009236 351.0
HKD3_k127_318420_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.848e-226 718.0
HKD3_k127_318420_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 8.39e-220 687.0
HKD3_k127_318420_10 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000001673 207.0
HKD3_k127_318420_11 LrgA family K06518 - - 0.000000000000000000000000002166 127.0
HKD3_k127_318420_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 604.0
HKD3_k127_318420_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 589.0
HKD3_k127_318420_4 PFAM FAD linked oxidase domain protein K00104,K11472 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 470.0
HKD3_k127_318420_5 NAD(P) transhydrogenase, alpha subunit K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 466.0
HKD3_k127_318420_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 490.0
HKD3_k127_318420_7 PFAM LrgB family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 337.0
HKD3_k127_318420_8 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000009823 238.0
HKD3_k127_318420_9 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000001658 250.0
HKD3_k127_3246762_0 helicase superfamily c-terminal domain K03724 - - 8.648e-267 830.0
HKD3_k127_3246762_1 Transporter, hydrophobe amphiphile efflux-1 (HAE1) family K18138 - - 1.322e-266 841.0
HKD3_k127_3246762_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 449.0
HKD3_k127_3246762_3 Tetracycline transcriptional repressor MAATS-type K03577 - - 0.000000000000000000000000000000000000000000002997 178.0
HKD3_k127_3256557_0 Elongator protein 3, MiaB family, Radical SAM - - - 5.003e-308 956.0
HKD3_k127_3256557_1 COG0841 Cation multidrug efflux pump K18902,K19594 - - 8.901e-300 939.0
HKD3_k127_3256557_10 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 381.0
HKD3_k127_3256557_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 347.0
HKD3_k127_3256557_12 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 330.0
HKD3_k127_3256557_13 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 318.0
HKD3_k127_3256557_14 Member of a two-component regulatory system K07644 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 329.0
HKD3_k127_3256557_15 LysR substrate binding domain K21645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 312.0
HKD3_k127_3256557_16 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 307.0
HKD3_k127_3256557_17 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 312.0
HKD3_k127_3256557_18 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000182 249.0
HKD3_k127_3256557_19 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18300 - - 0.0000000000000000000000000000000000000000000000000000000000000002406 241.0
HKD3_k127_3256557_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 1.291e-279 872.0
HKD3_k127_3256557_20 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000013 227.0
HKD3_k127_3256557_21 TRAP dicarboxylate transporter, DctQ subunit - - - 0.000000000000000000000000000000000000000000000000000000000002389 214.0
HKD3_k127_3256557_22 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000241 209.0
HKD3_k127_3256557_23 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000186 195.0
HKD3_k127_3256557_24 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000001119 198.0
HKD3_k127_3256557_25 family acetyltransferase K03824 - - 0.000000000000000000000000000000000000000000000000004169 191.0
HKD3_k127_3256557_26 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000006833 183.0
HKD3_k127_3256557_27 Sulfate permease family - - - 0.0000000000000000000000000000000000000000000001824 191.0
HKD3_k127_3256557_28 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000003022 151.0
HKD3_k127_3256557_29 Kelch motif - - - 0.000000000000000000000000000002642 135.0
HKD3_k127_3256557_3 TRAP-type C4-dicarboxylate transport system, large permease component - - - 1.876e-222 699.0
HKD3_k127_3256557_30 Pyridoxal-phosphate dependent enzyme K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.00000000000000000000000000008627 133.0
HKD3_k127_3256557_31 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000007976 116.0
HKD3_k127_3256557_32 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000005112 106.0
HKD3_k127_3256557_33 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000002722 103.0
HKD3_k127_3256557_34 Thioesterase-like superfamily - - - 0.000000000000002174 91.0
HKD3_k127_3256557_35 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000001763 64.0
HKD3_k127_3256557_36 Protein of unknown function (DUF4242) - - - 0.0000004459 59.0
HKD3_k127_3256557_37 Domain of unknown function (DUF4148) - - - 0.000007137 53.0
HKD3_k127_3256557_38 Transcriptional regulator - - - 0.00001949 49.0
HKD3_k127_3256557_39 membrane protein, terc K05794 - - 0.00004623 51.0
HKD3_k127_3256557_4 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 1.478e-198 632.0
HKD3_k127_3256557_40 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0004362 43.0
HKD3_k127_3256557_5 1-aminocyclopropane-1-carboxylate deaminase K01505,K05396,K17950 - 3.5.99.7,4.4.1.15,4.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 530.0
HKD3_k127_3256557_6 Trap dicarboxylate transporter, dctp subunit K21395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 507.0
HKD3_k127_3256557_7 PFAM aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007064 493.0
HKD3_k127_3256557_8 Di-haem cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 438.0
HKD3_k127_3256557_9 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 411.0
HKD3_k127_331826_0 PFAM AMP-dependent synthetase and ligase K00666 - - 6.746e-314 968.0
HKD3_k127_331826_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 5.188e-240 759.0
HKD3_k127_331826_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 538.0
HKD3_k127_331826_3 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 494.0
HKD3_k127_331826_4 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 397.0
HKD3_k127_331826_5 coa-binding K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000007615 225.0
HKD3_k127_331826_6 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000002136 210.0
HKD3_k127_3327044_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 4.066e-245 773.0
HKD3_k127_3327044_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 9.095e-243 756.0
HKD3_k127_3327044_10 - - - - 0.0001393 44.0
HKD3_k127_3327044_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 602.0
HKD3_k127_3327044_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 503.0
HKD3_k127_3327044_4 PFAM conserved K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 334.0
HKD3_k127_3327044_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000001949 222.0
HKD3_k127_3327044_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000000004333 135.0
HKD3_k127_3327044_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000006127 127.0
HKD3_k127_3327044_8 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000000002902 88.0
HKD3_k127_3327044_9 Tripartite tricarboxylate transporter TctB family K07794 - - 0.0000000000000000003501 96.0
HKD3_k127_344451_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 1.221e-282 874.0
HKD3_k127_344451_1 Lytic transglycosylase catalytic K08309 - - 5.555e-209 674.0
HKD3_k127_344451_2 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 610.0
HKD3_k127_344451_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 523.0
HKD3_k127_344451_4 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 404.0
HKD3_k127_344451_5 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 373.0
HKD3_k127_344451_6 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004991 347.0
HKD3_k127_344451_7 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 345.0
HKD3_k127_344451_8 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 326.0
HKD3_k127_344451_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007723 276.0
HKD3_k127_3564886_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 3.623e-213 670.0
HKD3_k127_3564886_1 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 607.0
HKD3_k127_3564886_2 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 611.0
HKD3_k127_3564886_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 592.0
HKD3_k127_3564886_4 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 321.0
HKD3_k127_3564886_5 Negative regulator of K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 284.0
HKD3_k127_3564886_6 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000002685 135.0
HKD3_k127_3564886_7 - K06950 - - 0.00000000000009751 73.0
HKD3_k127_3573175_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1648.0
HKD3_k127_3573175_1 Aminotransferase K14267 - 2.6.1.17 1.981e-201 634.0
HKD3_k127_3573175_10 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 366.0
HKD3_k127_3573175_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 348.0
HKD3_k127_3573175_12 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 283.0
HKD3_k127_3573175_13 Lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001921 295.0
HKD3_k127_3573175_14 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000869 249.0
HKD3_k127_3573175_15 SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain K07117 - - 0.00000000000000000000000000000000000000000000000000000000000000002156 234.0
HKD3_k127_3573175_16 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000000000000000000000000000000000000000002196 236.0
HKD3_k127_3573175_17 PFAM fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000002702 226.0
HKD3_k127_3573175_18 to COG2202 FOG PAS PAC domain of Yersinia UniRef RepID UPI00005F9950 - - - 0.000000000000006663 83.0
HKD3_k127_3573175_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 598.0
HKD3_k127_3573175_3 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 590.0
HKD3_k127_3573175_4 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 510.0
HKD3_k127_3573175_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 465.0
HKD3_k127_3573175_6 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 428.0
HKD3_k127_3573175_7 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 436.0
HKD3_k127_3573175_8 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 420.0
HKD3_k127_3573175_9 Glutathione S-transferase K11209 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 368.0
HKD3_k127_3664905_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1061.0
HKD3_k127_3664905_1 GTP-binding signal recognition particle K02404 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 581.0
HKD3_k127_3664905_10 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.000000000000000000000000000000000000000000000000000000000000000004847 231.0
HKD3_k127_3664905_11 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000001261 214.0
HKD3_k127_3664905_12 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000001076 212.0
HKD3_k127_3664905_13 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000000000000000000000000000000008147 181.0
HKD3_k127_3664905_14 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000005788 177.0
HKD3_k127_3664905_15 - - - - 0.000000000000000000000001132 114.0
HKD3_k127_3664905_16 Transcriptional regulator - - - 0.00000000000000000000003037 109.0
HKD3_k127_3664905_17 - - - - 0.0000000000000008348 86.0
HKD3_k127_3664905_18 anti-sigma-28 factor K02398 - - 0.000000000000005443 78.0
HKD3_k127_3664905_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 524.0
HKD3_k127_3664905_3 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007791 506.0
HKD3_k127_3664905_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 407.0
HKD3_k127_3664905_5 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 397.0
HKD3_k127_3664905_6 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 331.0
HKD3_k127_3664905_7 Histidine kinase K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 311.0
HKD3_k127_3664905_8 PFAM response regulator receiver K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
HKD3_k127_3664905_9 bacterial-type flagellum organization K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006261 265.0
HKD3_k127_3676378_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 5.617e-313 972.0
HKD3_k127_3676378_1 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 9e-209 663.0
HKD3_k127_3676378_10 UTRA K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 364.0
HKD3_k127_3676378_11 Amidohydrolase family K01485 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050228,GO:0050279 3.5.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001568 278.0
HKD3_k127_3676378_12 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.000000000000000000000000000000000000000000000000000000000000000004032 228.0
HKD3_k127_3676378_13 NADPH-quinone reductase (modulator of drug activity B) K00355 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000002338 229.0
HKD3_k127_3676378_14 PFAM succinate dehydrogenase cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
HKD3_k127_3676378_15 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000004943 209.0
HKD3_k127_3676378_16 PFAM Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000007114 188.0
HKD3_k127_3676378_17 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000001369 118.0
HKD3_k127_3676378_18 Signal peptide protein - - - 0.000000000000000000000705 106.0
HKD3_k127_3676378_19 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000001774 90.0
HKD3_k127_3676378_2 PFAM FAD linked oxidase domain protein - - - 1.178e-206 653.0
HKD3_k127_3676378_20 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 0.0000000000000000002121 90.0
HKD3_k127_3676378_21 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000009228 79.0
HKD3_k127_3676378_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 5.11e-196 615.0
HKD3_k127_3676378_4 PFAM sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 445.0
HKD3_k127_3676378_5 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 424.0
HKD3_k127_3676378_6 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 425.0
HKD3_k127_3676378_7 oxidoreductase FAD NAD(P)-binding domain protein K18069,K21324,K21607 - 1.1.1.404 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 432.0
HKD3_k127_3676378_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 421.0
HKD3_k127_3676378_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 424.0
HKD3_k127_3677430_0 Fe-S oxidoreductase K21834 - - 1.992e-237 758.0
HKD3_k127_3677430_1 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 572.0
HKD3_k127_3677430_10 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000704 65.0
HKD3_k127_3677430_2 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004378 483.0
HKD3_k127_3677430_3 Uroporphyrin-III C-methyltransferase K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 313.0
HKD3_k127_3677430_4 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 326.0
HKD3_k127_3677430_5 nitrate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 313.0
HKD3_k127_3677430_6 Bacterial regulatory proteins, luxR family K07684 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 304.0
HKD3_k127_3677430_7 Hydrogenase expression formation protein K03605 - - 0.00000000000000000000000000000000000000004761 165.0
HKD3_k127_3677430_8 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000000000000000007094 100.0
HKD3_k127_3677430_9 HupH hydrogenase expression protein, C-terminal conserved region - - - 0.00000000000000008816 91.0
HKD3_k127_3693738_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 493.0
HKD3_k127_3693738_1 Protein of unknown function (DUF2855) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 469.0
HKD3_k127_3693738_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 346.0
HKD3_k127_3693738_3 endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006225 240.0
HKD3_k127_3693738_4 bond formation protein DsbB K03611 - - 0.0000000000000000000000000000000000001475 162.0
HKD3_k127_3716503_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1101.0
HKD3_k127_3716503_1 GTP cyclohydrolase N terminal - - - 1.331e-242 771.0
HKD3_k127_3716503_10 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000004374 182.0
HKD3_k127_3716503_11 TIGRFAM ATP synthase, F0 - - - 0.0000000000000000000000000000000000000001151 153.0
HKD3_k127_3716503_12 Metal-sensitive transcriptional repressor - - - 0.00000000000000000000000000000000000006997 145.0
HKD3_k127_3716503_13 - - - - 0.000000000000000000000000000000000002812 141.0
HKD3_k127_3716503_14 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000007836 138.0
HKD3_k127_3716503_15 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000003279 112.0
HKD3_k127_3716503_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000004825 115.0
HKD3_k127_3716503_2 Protein of unknown function (DUF1688) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 527.0
HKD3_k127_3716503_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 517.0
HKD3_k127_3716503_4 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 386.0
HKD3_k127_3716503_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 335.0
HKD3_k127_3716503_6 Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 343.0
HKD3_k127_3716503_7 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 299.0
HKD3_k127_3716503_8 PFAM helix-turn-helix domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009276 303.0
HKD3_k127_3716503_9 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000007793 216.0
HKD3_k127_3744765_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 2.11e-236 733.0
HKD3_k127_3744765_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 576.0
HKD3_k127_3744765_10 Type II transport protein GspH K08084 - - 0.0000000000000000000000000000000000000217 150.0
HKD3_k127_3744765_11 type IV pilus modification protein PilV - - - 0.00000000000000000000000000000000000006158 165.0
HKD3_k127_3744765_12 family. transcriptional regulator K18842 - - 0.00000000000000000000000000000002436 128.0
HKD3_k127_3744765_13 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000002358 106.0
HKD3_k127_3744765_14 PIN domain - - - 0.0000000000000000004615 96.0
HKD3_k127_3744765_15 mRNA binding - - - 0.00000000000000009077 83.0
HKD3_k127_3744765_16 PFAM Uncharacterised protein family (UPF0150) - - - 0.00000000000005505 79.0
HKD3_k127_3744765_17 Antidote-toxin recognition MazE, bacterial antitoxin - - - 0.000000000317 64.0
HKD3_k127_3744765_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 466.0
HKD3_k127_3744765_3 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 322.0
HKD3_k127_3744765_4 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003461 295.0
HKD3_k127_3744765_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006458 261.0
HKD3_k127_3744765_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000000000000000000000000000000008046 237.0
HKD3_k127_3744765_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000001773 221.0
HKD3_k127_3744765_8 PFAM PemK family protein K18841 - - 0.0000000000000000000000000000000000000000000000006233 177.0
HKD3_k127_3744765_9 General secretion pathway protein K02672 - - 0.0000000000000000000000000000000000000000000001958 178.0
HKD3_k127_3752034_0 Ftsk_gamma K03466 - - 0.0 1165.0
HKD3_k127_3752034_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.49e-273 854.0
HKD3_k127_3752034_10 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 531.0
HKD3_k127_3752034_11 FAD dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 509.0
HKD3_k127_3752034_12 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 504.0
HKD3_k127_3752034_13 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 452.0
HKD3_k127_3752034_14 epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 446.0
HKD3_k127_3752034_15 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 419.0
HKD3_k127_3752034_16 Transcriptional regulator, Crp Fnr family K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 377.0
HKD3_k127_3752034_17 Lanthionine synthetase C-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 372.0
HKD3_k127_3752034_18 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 350.0
HKD3_k127_3752034_19 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 346.0
HKD3_k127_3752034_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 2.135e-228 712.0
HKD3_k127_3752034_20 Eukaryotic integral membrane protein (DUF1751) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 289.0
HKD3_k127_3752034_21 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 284.0
HKD3_k127_3752034_22 Nudix N-terminal K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001982 287.0
HKD3_k127_3752034_23 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000005112 237.0
HKD3_k127_3752034_24 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000001039 151.0
HKD3_k127_3752034_25 coenzyme F420 binding K07226 - - 0.00000000000000000000000000000005091 136.0
HKD3_k127_3752034_26 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000002828 124.0
HKD3_k127_3752034_27 NmrA-like family - - - 0.00000000000000000000000000000227 132.0
HKD3_k127_3752034_28 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000000000004624 110.0
HKD3_k127_3752034_29 Putative regulatory protein - - - 0.000000000001988 74.0
HKD3_k127_3752034_3 PFAM fatty acid desaturase K00507 - 1.14.19.1 1.032e-222 697.0
HKD3_k127_3752034_4 MgsA AAA+ ATPase C terminal K07478 - - 5.439e-210 666.0
HKD3_k127_3752034_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 612.0
HKD3_k127_3752034_6 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 582.0
HKD3_k127_3752034_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 583.0
HKD3_k127_3752034_8 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 575.0
HKD3_k127_3752034_9 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 556.0
HKD3_k127_3787706_0 ROK family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 542.0
HKD3_k127_3787706_1 epimerase K19073 - 1.3.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 361.0
HKD3_k127_3787706_2 PFAM PEBP family protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002575 284.0
HKD3_k127_3787706_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046116,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0072531,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1990397 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002627 259.0
HKD3_k127_3787706_4 Belongs to the RbsD FucU family K02431 - 5.1.3.29 0.000000000000000000000000000000000000000000000000000000000000000005789 228.0
HKD3_k127_3787706_5 ATPases associated with a variety of cellular activities K10554 - - 0.0000000000000000000000000000000000004944 139.0
HKD3_k127_3800954_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.0 1094.0
HKD3_k127_3800954_1 MOFRL family K11529 - 2.7.1.165 1.092e-217 697.0
HKD3_k127_3800954_10 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006787 413.0
HKD3_k127_3800954_11 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000002823 228.0
HKD3_k127_3800954_12 Protein of unknown function (DUF454) K09790 - - 0.0000000000000000000000000000000000000000000000000002472 190.0
HKD3_k127_3800954_13 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000001335 184.0
HKD3_k127_3800954_2 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase K00101,K00104 - 1.1.2.3,1.1.3.15 1.294e-213 668.0
HKD3_k127_3800954_3 Oxidoreductase K10219 - 1.1.1.312 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 565.0
HKD3_k127_3800954_4 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 545.0
HKD3_k127_3800954_5 6-phosphogluconate dehydrogenase, NAD-binding K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 469.0
HKD3_k127_3800954_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 460.0
HKD3_k127_3800954_7 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 454.0
HKD3_k127_3800954_8 Protocatechuate 4,5-dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 447.0
HKD3_k127_3800954_9 Transcriptional regulator, AraC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 442.0
HKD3_k127_3808870_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1319.0
HKD3_k127_3808870_1 protein related to plant photosystem II stability assembly factor - - - 2.719e-210 659.0
HKD3_k127_3808870_10 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000001712 127.0
HKD3_k127_3808870_11 - - - - 0.000000000000005608 80.0
HKD3_k127_3808870_12 Ankyrin repeats (many copies) - - - 0.00000000003839 75.0
HKD3_k127_3808870_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 557.0
HKD3_k127_3808870_3 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 533.0
HKD3_k127_3808870_4 Glutathione S-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 311.0
HKD3_k127_3808870_5 Putative 2OG-Fe(II) oxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 290.0
HKD3_k127_3808870_6 Exopolysaccharide synthesis, ExoD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003586 266.0
HKD3_k127_3808870_7 'Cold-shock' DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000005468 242.0
HKD3_k127_3808870_8 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000008832 207.0
HKD3_k127_3808870_9 ThiS family K03636 - - 0.00000000000000000000000000001244 120.0
HKD3_k127_3842488_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1791.0
HKD3_k127_3842488_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1515.0
HKD3_k127_3842488_10 Major facilitator Superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 614.0
HKD3_k127_3842488_11 AFG1-like ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 596.0
HKD3_k127_3842488_12 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 541.0
HKD3_k127_3842488_13 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 497.0
HKD3_k127_3842488_14 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 430.0
HKD3_k127_3842488_15 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 412.0
HKD3_k127_3842488_16 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 397.0
HKD3_k127_3842488_17 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005741 347.0
HKD3_k127_3842488_18 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 318.0
HKD3_k127_3842488_19 Type IV pilus biogenesis stability protein PilW K02656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003384 295.0
HKD3_k127_3842488_2 acyl-CoA dehydrogenase K20035 - - 1.607e-319 986.0
HKD3_k127_3842488_20 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000507 257.0
HKD3_k127_3842488_21 Domain of unknown function (DUF4115) K15539 - - 0.0000000000000000000000000000000000000000000000000000000004827 218.0
HKD3_k127_3842488_22 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000003484 195.0
HKD3_k127_3842488_23 PspC domain - - - 0.00000000000000000000000000000000006954 137.0
HKD3_k127_3842488_24 Arm DNA-binding domain - - - 0.00000000000000000000000000000003545 128.0
HKD3_k127_3842488_25 Protein of unknown function (DUF465) - - - 0.00000000000000000000005491 105.0
HKD3_k127_3842488_3 HELICc2 K03722 - 3.6.4.12 1.39e-272 855.0
HKD3_k127_3842488_4 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 7.138e-272 853.0
HKD3_k127_3842488_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.563e-232 723.0
HKD3_k127_3842488_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 4.496e-214 674.0
HKD3_k127_3842488_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 4.604e-204 642.0
HKD3_k127_3842488_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 2.262e-200 629.0
HKD3_k127_3842488_9 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 3.374e-196 640.0
HKD3_k127_3865050_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1198.0
HKD3_k127_3865050_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0 1017.0
HKD3_k127_3865050_10 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 471.0
HKD3_k127_3865050_11 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 466.0
HKD3_k127_3865050_12 von Willebrand factor, type A K02448 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 460.0
HKD3_k127_3865050_13 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 434.0
HKD3_k127_3865050_14 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 414.0
HKD3_k127_3865050_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 364.0
HKD3_k127_3865050_16 branched-chain amino acid permease (azaleucine resistance) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 344.0
HKD3_k127_3865050_17 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 334.0
HKD3_k127_3865050_18 CbbQ NirQ NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 314.0
HKD3_k127_3865050_19 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 307.0
HKD3_k127_3865050_2 Protein of unknown function (DUF1631) - - - 7.129e-283 890.0
HKD3_k127_3865050_20 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 302.0
HKD3_k127_3865050_21 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 286.0
HKD3_k127_3865050_22 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002586 274.0
HKD3_k127_3865050_23 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002484 261.0
HKD3_k127_3865050_24 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000304 253.0
HKD3_k127_3865050_25 Cytochrome c K02305 - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 238.0
HKD3_k127_3865050_26 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000000003288 239.0
HKD3_k127_3865050_27 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000001765 239.0
HKD3_k127_3865050_28 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000000000000000005757 226.0
HKD3_k127_3865050_29 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000000000000000000000000000005948 243.0
HKD3_k127_3865050_3 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 1.226e-269 835.0
HKD3_k127_3865050_30 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000000000000001775 227.0
HKD3_k127_3865050_31 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000008761 217.0
HKD3_k127_3865050_32 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000000002083 192.0
HKD3_k127_3865050_33 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000001388 197.0
HKD3_k127_3865050_34 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000000000000000000005917 174.0
HKD3_k127_3865050_35 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000000003626 176.0
HKD3_k127_3865050_36 Universal stress protein - - - 0.0000000000000000000000000000000000000000008238 163.0
HKD3_k127_3865050_37 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000003435 149.0
HKD3_k127_3865050_38 Branched-chain amino acid transport - - - 0.000000000000000000000000000000000000004779 164.0
HKD3_k127_3865050_39 - - - - 0.0000000000000000000000000000000000005284 147.0
HKD3_k127_3865050_4 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.345e-253 785.0
HKD3_k127_3865050_40 - - - - 0.00000000000000000000000000000000003861 136.0
HKD3_k127_3865050_41 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000004791 139.0
HKD3_k127_3865050_42 Pfam:DUF59 - - - 0.0000000000000000000000001101 111.0
HKD3_k127_3865050_43 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000000000002264 102.0
HKD3_k127_3865050_44 Ribosomal protein L30 K02907 - - 0.00000000000000000001746 98.0
HKD3_k127_3865050_45 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000002312 76.0
HKD3_k127_3865050_46 - - - - 0.000000001835 66.0
HKD3_k127_3865050_5 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.421e-232 764.0
HKD3_k127_3865050_6 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 1.692e-217 686.0
HKD3_k127_3865050_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 593.0
HKD3_k127_3865050_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 561.0
HKD3_k127_3865050_9 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 527.0
HKD3_k127_3892571_0 Belongs to the IlvD Edd family K01690 - 4.2.1.12 1.726e-309 957.0
HKD3_k127_3892571_1 ABC transporter K06020 - 3.6.3.25 1.074e-292 904.0
HKD3_k127_3892571_10 - - - - 0.0000000000000000000000000000000000000000000000000000000004425 218.0
HKD3_k127_3892571_11 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000000000000000000005834 222.0
HKD3_k127_3892571_12 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000322 134.0
HKD3_k127_3892571_13 - - - - 0.000000000000000007649 89.0
HKD3_k127_3892571_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 569.0
HKD3_k127_3892571_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 430.0
HKD3_k127_3892571_4 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 360.0
HKD3_k127_3892571_5 Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 338.0
HKD3_k127_3892571_6 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 319.0
HKD3_k127_3892571_7 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 285.0
HKD3_k127_3892571_8 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000001907 247.0
HKD3_k127_3892571_9 Protein of unknown function (DUF3299) K09950 - - 0.00000000000000000000000000000000000000000000000000000000004169 214.0
HKD3_k127_390555_0 Major facilitator Superfamily K08218 - - 4.735e-249 779.0
HKD3_k127_390555_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.78e-241 764.0
HKD3_k127_390555_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 496.0
HKD3_k127_390555_3 Peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 447.0
HKD3_k127_390555_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 377.0
HKD3_k127_390555_5 Barstar (barnase inhibitor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001631 246.0
HKD3_k127_390555_6 Ribonuclease K01167 - 3.1.27.3 0.0000000000000000000000000000000000000006101 155.0
HKD3_k127_3940476_0 Zn_pept - - - 5.493e-316 974.0
HKD3_k127_3940476_1 AMP-binding enzyme K01897 - 6.2.1.3 3.075e-268 835.0
HKD3_k127_3940476_10 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 438.0
HKD3_k127_3940476_11 Hpt domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009418 408.0
HKD3_k127_3940476_12 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 369.0
HKD3_k127_3940476_13 signal transduction protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 350.0
HKD3_k127_3940476_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886,K16066 - 1.1.1.276,1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 312.0
HKD3_k127_3940476_15 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 298.0
HKD3_k127_3940476_16 AsnC-type helix-turn-helix domain K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002072 254.0
HKD3_k127_3940476_17 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008106 241.0
HKD3_k127_3940476_18 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003525 233.0
HKD3_k127_3940476_19 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000336 239.0
HKD3_k127_3940476_2 AMP-binding enzyme K01897 - 6.2.1.3 9.03e-258 806.0
HKD3_k127_3940476_20 ABC transporter substrate binding protein - - - 0.0000000000000000000000000000000000000000000000001912 190.0
HKD3_k127_3940476_21 RNA-binding protein - - - 0.000000000000000000000000000000000000000000000001617 186.0
HKD3_k127_3940476_22 nitrogen regulatory protein P-II - - - 0.0000000000000000000000000000002263 138.0
HKD3_k127_3940476_23 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000008298 85.0
HKD3_k127_3940476_24 His Kinase A (phosphoacceptor) domain - - - 0.000000000001956 81.0
HKD3_k127_3940476_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 1.101e-239 766.0
HKD3_k127_3940476_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00457 - 1.13.11.27 9.771e-211 670.0
HKD3_k127_3940476_5 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 566.0
HKD3_k127_3940476_6 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 571.0
HKD3_k127_3940476_7 PFAM binding-protein-dependent transport systems inner membrane component K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 553.0
HKD3_k127_3940476_8 Biopterin-dependent aromatic amino acid hydroxylase K00500 - 1.14.16.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003226 489.0
HKD3_k127_3940476_9 Virulence factor membrane-bound polymerase, C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 466.0
HKD3_k127_3946112_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.144e-298 939.0
HKD3_k127_3946112_1 Class III cytochrome C family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 428.0
HKD3_k127_3946112_2 - - - - 0.00000000000000000000000001519 109.0
HKD3_k127_394846_0 Domain of unknown function (DUF3362) - - - 4.026e-306 949.0
HKD3_k127_394846_1 Flavin-binding monooxygenase-like K07222 - - 2.879e-287 893.0
HKD3_k127_394846_2 Amidohydrolase family - - - 4.695e-267 837.0
HKD3_k127_394846_3 Cellulose synthase - - - 1.642e-212 696.0
HKD3_k127_394846_4 lytic transglycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 333.0
HKD3_k127_3966898_0 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K13482 - 1.17.1.4 0.0 1006.0
HKD3_k127_3966898_1 Amidohydrolase K10220 - 4.2.1.83 1.582e-210 659.0
HKD3_k127_3966898_2 Amidohydrolase K10221 - 3.1.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 603.0
HKD3_k127_3966898_3 Domain of unknown function (DUF1932) K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 447.0
HKD3_k127_3966898_4 LysR family K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 389.0
HKD3_k127_3966898_5 TIGRFAM xanthine dehydrogenase accessory protein XdhC K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 372.0
HKD3_k127_3966898_6 Aldolase/RraA K10218 - 4.1.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 375.0
HKD3_k127_3966898_7 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 299.0
HKD3_k127_3966898_8 Aromatic-ring-opening dioxygenase LigAB, LigA subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007719 258.0
HKD3_k127_3966898_9 Catalytic LigB subunit of aromatic ring-opening dioxygenase K04099,K04101 - 1.13.11.57,1.13.11.8 0.00000000000000000000000000000000000000000000000000000000000000000000000003058 258.0
HKD3_k127_3982341_0 ABC transporter K06147 - - 6.983e-307 955.0
HKD3_k127_3982341_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 4.622e-196 614.0
HKD3_k127_3982341_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 586.0
HKD3_k127_3982341_3 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 595.0
HKD3_k127_3982341_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 363.0
HKD3_k127_3982341_5 Thioesterase superfamily protein K10806 - - 0.00000000000000000000000000000000000000000000000000000000002859 208.0
HKD3_k127_3982341_6 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000000000000000006544 187.0
HKD3_k127_3982341_7 NYN domain - - - 0.000000000000000000000000000006675 134.0
HKD3_k127_4000675_0 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.0 1079.0
HKD3_k127_4000675_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 2.067e-273 875.0
HKD3_k127_4000675_10 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 443.0
HKD3_k127_4000675_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 437.0
HKD3_k127_4000675_12 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 429.0
HKD3_k127_4000675_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 377.0
HKD3_k127_4000675_14 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 373.0
HKD3_k127_4000675_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 378.0
HKD3_k127_4000675_16 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 355.0
HKD3_k127_4000675_17 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 299.0
HKD3_k127_4000675_18 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005159 263.0
HKD3_k127_4000675_19 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000000000000003728 211.0
HKD3_k127_4000675_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 9.726e-267 840.0
HKD3_k127_4000675_20 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000007997 217.0
HKD3_k127_4000675_21 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000242 196.0
HKD3_k127_4000675_22 PFAM AsmA family protein K07289,K07290 - - 0.00000000000000000000002241 118.0
HKD3_k127_4000675_23 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000000623 107.0
HKD3_k127_4000675_24 cytochrome oxidase maturation protein - - - 0.0000000000000007926 79.0
HKD3_k127_4000675_26 AsmA-like C-terminal region K07290 - - 0.0003852 55.0
HKD3_k127_4000675_3 Patatin-like phospholipase K07001 - - 2.178e-253 801.0
HKD3_k127_4000675_4 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 3.231e-244 773.0
HKD3_k127_4000675_5 receptor K02014 - - 2.268e-239 770.0
HKD3_k127_4000675_6 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 597.0
HKD3_k127_4000675_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 609.0
HKD3_k127_4000675_8 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006538 515.0
HKD3_k127_4000675_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 485.0
HKD3_k127_403807_0 TonB C terminal K03646 - - 0.0000000000000000000000000000000000000000000000000000000000001528 223.0
HKD3_k127_403807_1 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000000000009077 193.0
HKD3_k127_403807_2 PFAM MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000007876 187.0
HKD3_k127_403807_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000002802 188.0
HKD3_k127_403807_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000004025 121.0
HKD3_k127_403807_5 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000002581 106.0
HKD3_k127_403807_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000001124 88.0
HKD3_k127_4066717_0 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 597.0
HKD3_k127_4066717_1 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008464 374.0
HKD3_k127_4075687_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 4.988e-266 823.0
HKD3_k127_4075687_1 Protein of unknown function (DUF1631) - - - 5.197e-225 724.0
HKD3_k127_4075687_10 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 380.0
HKD3_k127_4075687_11 cytochrome c1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 391.0
HKD3_k127_4075687_12 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 351.0
HKD3_k127_4075687_13 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 348.0
HKD3_k127_4075687_14 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 317.0
HKD3_k127_4075687_15 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 314.0
HKD3_k127_4075687_16 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008743 267.0
HKD3_k127_4075687_17 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000003973 248.0
HKD3_k127_4075687_18 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000000000000000000000000005947 237.0
HKD3_k127_4075687_19 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000000000000000000000000000000000000000000009654 236.0
HKD3_k127_4075687_2 Multicopper oxidase K22348 - 1.16.3.3 1.228e-216 702.0
HKD3_k127_4075687_20 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000812 238.0
HKD3_k127_4075687_21 Starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000000000000000000000000001745 233.0
HKD3_k127_4075687_22 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000000000000001145 200.0
HKD3_k127_4075687_23 membrane - - - 0.00000000000000000000000000000000000000000000000000005023 196.0
HKD3_k127_4075687_24 Phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.000000000000000000000000000000000000000000000000003724 183.0
HKD3_k127_4075687_25 Type III secretion system lipoprotein chaperone (YscW) - - - 0.0000000000000000000000000000000000008383 156.0
HKD3_k127_4075687_26 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000002129 110.0
HKD3_k127_4075687_27 - - - - 0.000000000000005867 80.0
HKD3_k127_4075687_28 - - - - 0.0000000003883 64.0
HKD3_k127_4075687_29 DNA excision - - - 0.000008911 52.0
HKD3_k127_4075687_3 Arm DNA-binding domain - - - 8.421e-202 636.0
HKD3_k127_4075687_30 - - - - 0.00002289 54.0
HKD3_k127_4075687_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 537.0
HKD3_k127_4075687_5 Trypsin K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 475.0
HKD3_k127_4075687_6 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 487.0
HKD3_k127_4075687_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 452.0
HKD3_k127_4075687_8 Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 399.0
HKD3_k127_4075687_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 395.0
HKD3_k127_40990_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1083.0
HKD3_k127_40990_1 Poly-beta-hydroxybutyrate polymerase K03821 - - 1.174e-273 862.0
HKD3_k127_40990_2 COG0075 Serine-pyruvate aminotransferase archaeal aspartate aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008606 537.0
HKD3_k127_40990_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 491.0
HKD3_k127_40990_4 LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 397.0
HKD3_k127_40990_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 380.0
HKD3_k127_40990_6 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000003104 230.0
HKD3_k127_43624_0 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.706e-284 880.0
HKD3_k127_43624_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 3.724e-283 886.0
HKD3_k127_43624_10 Glyoxalase bleomycin resistance protein dioxygenase K06991 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001054 254.0
HKD3_k127_43624_11 - - - - 0.0000000000000000000000000000000000000000000000000000000003147 209.0
HKD3_k127_43624_12 aspartic-type endopeptidase activity K06985 - - 0.0000000000000000000000000000000000000000000000000000002935 204.0
HKD3_k127_43624_13 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000008514 161.0
HKD3_k127_43624_14 Protein of unknown function (DUF3567) - - - 0.000000000000000000000000000002219 122.0
HKD3_k127_43624_15 chlorophyll binding - - - 0.0000000004395 69.0
HKD3_k127_43624_2 homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 574.0
HKD3_k127_43624_3 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 542.0
HKD3_k127_43624_4 FIST_C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 537.0
HKD3_k127_43624_5 Putative diguanylate phosphodiesterase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 520.0
HKD3_k127_43624_6 SMART AAA ATPase K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008274 441.0
HKD3_k127_43624_7 Fumarylacetoacetate (Faa) hydrolase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 431.0
HKD3_k127_43624_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 396.0
HKD3_k127_43624_9 with different specificities (related to short-chain alcohol K00034 - 1.1.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 312.0
HKD3_k127_4419621_0 May be involved in recombinational repair of damaged DNA K03631 - - 2.43e-237 746.0
HKD3_k127_4419621_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 7.125e-200 637.0
HKD3_k127_4419621_10 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000000000000000006996 244.0
HKD3_k127_4419621_11 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000616 134.0
HKD3_k127_4419621_12 - - - - 0.00000000000000000000001525 102.0
HKD3_k127_4419621_13 Aldolase/RraA - - - 0.0000003795 54.0
HKD3_k127_4419621_14 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00007439 46.0
HKD3_k127_4419621_2 Protein of unknown function (DUF3422) - - - 9.872e-196 620.0
HKD3_k127_4419621_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 549.0
HKD3_k127_4419621_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 526.0
HKD3_k127_4419621_5 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 486.0
HKD3_k127_4419621_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 429.0
HKD3_k127_4419621_7 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 409.0
HKD3_k127_4419621_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000127 284.0
HKD3_k127_4419621_9 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000152 263.0
HKD3_k127_464712_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1397.0
HKD3_k127_464712_1 PFAM Peptidoglycan-binding domain 1 protein K21470 - - 8.582e-212 671.0
HKD3_k127_464712_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 526.0
HKD3_k127_464712_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006921 434.0
HKD3_k127_464712_4 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 400.0
HKD3_k127_464712_5 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000001387 273.0
HKD3_k127_464712_6 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.00000000000000000000000000000000000000000000000000004465 188.0
HKD3_k127_469328_0 Transport of potassium into the cell K03549 - - 5.498e-319 987.0
HKD3_k127_469328_1 glutamate--cysteine ligase K01919 - 6.3.2.2 1.583e-256 794.0
HKD3_k127_469328_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 490.0
HKD3_k127_469328_3 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000004731 211.0
HKD3_k127_469328_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000007237 197.0
HKD3_k127_469328_5 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000001704 189.0
HKD3_k127_4836440_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 7.256e-312 990.0
HKD3_k127_4836440_1 Carboxyl transferase domain K13778 - 6.4.1.5 9.926e-294 909.0
HKD3_k127_4836440_10 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 604.0
HKD3_k127_4836440_11 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 571.0
HKD3_k127_4836440_12 PFAM peptidase M48 Ste24p K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 562.0
HKD3_k127_4836440_13 Histidine kinase K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 550.0
HKD3_k127_4836440_14 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 537.0
HKD3_k127_4836440_15 glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 513.0
HKD3_k127_4836440_16 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 494.0
HKD3_k127_4836440_17 KR domain K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 486.0
HKD3_k127_4836440_18 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 473.0
HKD3_k127_4836440_19 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008546 445.0
HKD3_k127_4836440_2 Biotin carboxylase C-terminal domain K13777 - 6.4.1.5 4.388e-254 807.0
HKD3_k127_4836440_20 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 431.0
HKD3_k127_4836440_21 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 430.0
HKD3_k127_4836440_22 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 409.0
HKD3_k127_4836440_23 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 410.0
HKD3_k127_4836440_24 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 413.0
HKD3_k127_4836440_25 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 396.0
HKD3_k127_4836440_26 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 386.0
HKD3_k127_4836440_27 Enoyl-CoA hydratase/isomerase K13816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 396.0
HKD3_k127_4836440_28 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 376.0
HKD3_k127_4836440_29 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 392.0
HKD3_k127_4836440_3 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 3.398e-233 736.0
HKD3_k127_4836440_30 PFAM response regulator receiver K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 366.0
HKD3_k127_4836440_31 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 358.0
HKD3_k127_4836440_32 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 345.0
HKD3_k127_4836440_33 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 309.0
HKD3_k127_4836440_34 Cytochrome b/b6/petB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 313.0
HKD3_k127_4836440_35 enoyl-CoA hydratase K13779 - 4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 327.0
HKD3_k127_4836440_36 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 306.0
HKD3_k127_4836440_37 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 288.0
HKD3_k127_4836440_38 Flavodoxin domain K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 288.0
HKD3_k127_4836440_39 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000419 244.0
HKD3_k127_4836440_4 Circadian clock protein kaic K08482 - - 2.24e-232 729.0
HKD3_k127_4836440_40 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000266 238.0
HKD3_k127_4836440_41 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000001951 229.0
HKD3_k127_4836440_42 Lactoylglutathione lyase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000002345 223.0
HKD3_k127_4836440_43 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000007704 235.0
HKD3_k127_4836440_44 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000000122 221.0
HKD3_k127_4836440_45 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000000000000000000000000000000000000000001274 209.0
HKD3_k127_4836440_46 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000000000000000001334 211.0
HKD3_k127_4836440_47 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001864 205.0
HKD3_k127_4836440_48 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000000000000000000002154 210.0
HKD3_k127_4836440_49 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000005006 186.0
HKD3_k127_4836440_5 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 2.164e-229 716.0
HKD3_k127_4836440_50 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000008689 164.0
HKD3_k127_4836440_51 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000001736 158.0
HKD3_k127_4836440_52 PFAM Transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000002334 169.0
HKD3_k127_4836440_53 - - - - 0.000000000000000000001032 104.0
HKD3_k127_4836440_54 Dihaem cytochrome c - - - 0.000000000000000000007135 104.0
HKD3_k127_4836440_55 - - - - 0.00000000000000000002022 97.0
HKD3_k127_4836440_56 - - - - 0.0000000000000000004303 92.0
HKD3_k127_4836440_57 Protein of unknown function (DUF1624) - - - 0.000000000000000001257 87.0
HKD3_k127_4836440_58 Acid phosphatase homologues - - - 0.00000000000000002779 94.0
HKD3_k127_4836440_59 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.000003248 56.0
HKD3_k127_4836440_6 RNB K01147 - 3.1.13.1 7.529e-222 697.0
HKD3_k127_4836440_60 - - - - 0.00005459 55.0
HKD3_k127_4836440_61 Pfam:DUF3457 - - - 0.00008238 49.0
HKD3_k127_4836440_7 Phospholipase D. Active site motifs. K00995,K06131 - 2.7.8.5 1.254e-208 659.0
HKD3_k127_4836440_8 RNA-metabolising metallo-beta-lactamase K07576 - - 2.131e-203 644.0
HKD3_k127_4836440_9 Belongs to the thiolase family K00626 - 2.3.1.9 2.511e-197 641.0
HKD3_k127_4839820_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1255.0
HKD3_k127_4839820_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 2.106e-289 898.0
HKD3_k127_4839820_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 577.0
HKD3_k127_4839820_3 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 551.0
HKD3_k127_4839820_4 Glycine cleavage system T protein K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 529.0
HKD3_k127_4839820_5 Asp Glu Hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003862 282.0
HKD3_k127_4839820_6 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004143 240.0
HKD3_k127_4842737_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1103.0
HKD3_k127_4842737_1 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 5.324e-221 696.0
HKD3_k127_4842737_10 Molecular chaperone. Has ATPase activity K04079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 462.0
HKD3_k127_4842737_11 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 489.0
HKD3_k127_4842737_12 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 450.0
HKD3_k127_4842737_13 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004462 422.0
HKD3_k127_4842737_14 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 403.0
HKD3_k127_4842737_15 PFAM Cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 371.0
HKD3_k127_4842737_16 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 336.0
HKD3_k127_4842737_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 287.0
HKD3_k127_4842737_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007121 271.0
HKD3_k127_4842737_19 Protein of unknown function (DUF2726) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001293 278.0
HKD3_k127_4842737_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 6.426e-217 683.0
HKD3_k127_4842737_20 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000000000000001679 243.0
HKD3_k127_4842737_21 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000000000005683 237.0
HKD3_k127_4842737_22 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000001543 226.0
HKD3_k127_4842737_23 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000259 214.0
HKD3_k127_4842737_24 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000002968 212.0
HKD3_k127_4842737_25 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000001332 204.0
HKD3_k127_4842737_26 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000002197 147.0
HKD3_k127_4842737_27 - - - - 0.0000000000000000000000000000004281 126.0
HKD3_k127_4842737_28 - - - - 0.0000000000000000000000000000004831 128.0
HKD3_k127_4842737_3 AMP-binding enzyme K01912 - 6.2.1.30 3.111e-210 659.0
HKD3_k127_4842737_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 587.0
HKD3_k127_4842737_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 532.0
HKD3_k127_4842737_6 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 539.0
HKD3_k127_4842737_7 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 521.0
HKD3_k127_4842737_8 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 500.0
HKD3_k127_4842737_9 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 500.0
HKD3_k127_4863028_0 acetolactate synthase K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 441.0
HKD3_k127_4863028_1 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 263.0
HKD3_k127_4863028_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000004931 254.0
HKD3_k127_4863028_3 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000001148 229.0
HKD3_k127_4863028_4 TAP-like protein - - - 0.0000000000000000000000000000000000000000000001105 170.0
HKD3_k127_4863028_5 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000000000004633 143.0
HKD3_k127_4863028_6 Protein of unknown function (DUF3619) - - - 0.0000000000000000000009503 104.0
HKD3_k127_4877726_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1442.0
HKD3_k127_4877726_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 599.0
HKD3_k127_4883425_0 Hydantoinase/oxoprolinase N-terminal region K01469 - 3.5.2.9 0.0 1884.0
HKD3_k127_4883425_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1624.0
HKD3_k127_4883425_10 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002985 256.0
HKD3_k127_4883425_11 - - - - 0.000000000000000000000000000000000000000028 164.0
HKD3_k127_4883425_2 oxidoreductase K04090 - 1.2.7.8 0.0 1277.0
HKD3_k127_4883425_3 Histidine kinase - - - 5.552e-205 658.0
HKD3_k127_4883425_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.063e-202 634.0
HKD3_k127_4883425_5 Diguanylate cyclase - - - 9.842e-196 660.0
HKD3_k127_4883425_6 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 617.0
HKD3_k127_4883425_7 EamA-like transporter family K15268 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 380.0
HKD3_k127_4883425_8 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 378.0
HKD3_k127_4883425_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 374.0
HKD3_k127_4910264_0 Peptidase family M3 K01414 - 3.4.24.70 0.0 1036.0
HKD3_k127_4910264_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.451e-267 860.0
HKD3_k127_4910264_10 pyridine nucleotide-disulfide oxidoreductase family protein K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 431.0
HKD3_k127_4910264_11 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 388.0
HKD3_k127_4910264_12 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 388.0
HKD3_k127_4910264_13 LysR substrate binding domain K18900 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 373.0
HKD3_k127_4910264_14 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 364.0
HKD3_k127_4910264_15 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 359.0
HKD3_k127_4910264_16 hydroxyneurosporene synthase K09844 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016122,GO:0016123,GO:0016829,GO:0016835,GO:0016836,GO:0018904,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046148,GO:0071704,GO:1901178,GO:1901180,GO:1901503,GO:1901576 4.2.1.131 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 348.0
HKD3_k127_4910264_17 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 309.0
HKD3_k127_4910264_18 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 288.0
HKD3_k127_4910264_19 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001031 243.0
HKD3_k127_4910264_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 5.604e-224 709.0
HKD3_k127_4910264_20 Cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000000000000001434 222.0
HKD3_k127_4910264_21 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000102 205.0
HKD3_k127_4910264_22 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000000000000000000000000000000002242 190.0
HKD3_k127_4910264_23 Regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000006067 173.0
HKD3_k127_4910264_24 Ni,Fe-hydrogenase I large subunit - - - 0.0000000000000000000000000000000000000000000001848 184.0
HKD3_k127_4910264_25 Glutaredoxin - - - 0.00000000000000000000000000000000000001984 151.0
HKD3_k127_4910264_26 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000001361 115.0
HKD3_k127_4910264_27 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000003562 113.0
HKD3_k127_4910264_28 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000000000006876 108.0
HKD3_k127_4910264_3 Flavin containing amine oxidoreductase K09845 - 1.3.99.27 1.597e-198 631.0
HKD3_k127_4910264_4 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 601.0
HKD3_k127_4910264_5 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 533.0
HKD3_k127_4910264_6 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 475.0
HKD3_k127_4910264_7 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 462.0
HKD3_k127_4910264_8 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 444.0
HKD3_k127_4910264_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 435.0
HKD3_k127_4919072_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1103.0
HKD3_k127_4919072_1 DNA topoisomerase III K03169 - 5.99.1.2 0.0 1070.0
HKD3_k127_4919072_10 UPF0056 inner membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007565 274.0
HKD3_k127_4919072_11 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000001924 288.0
HKD3_k127_4919072_12 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000004726 258.0
HKD3_k127_4919072_13 Cysteine-rich motif following a subset of SET domains K07117 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002836 245.0
HKD3_k127_4919072_14 Sporulation domain protein - - - 0.000000004352 69.0
HKD3_k127_4919072_2 oxidoreductase activity - - - 8.504e-318 988.0
HKD3_k127_4919072_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 586.0
HKD3_k127_4919072_4 UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 542.0
HKD3_k127_4919072_5 Aldo/keto reductase family K19265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 539.0
HKD3_k127_4919072_6 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 543.0
HKD3_k127_4919072_7 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 533.0
HKD3_k127_4919072_8 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 329.0
HKD3_k127_4919072_9 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001908 281.0
HKD3_k127_4941226_0 NADPH-dependent glutamate synthase beta - - - 0.0 1055.0
HKD3_k127_4941226_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.0 1042.0
HKD3_k127_4941226_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 1.31e-199 627.0
HKD3_k127_4941226_3 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 436.0
HKD3_k127_4941226_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 329.0
HKD3_k127_4941226_5 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 301.0
HKD3_k127_4941226_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000008828 231.0
HKD3_k127_4941226_7 - - - - 0.00000000000000000000000000000000000000000000000000001888 196.0
HKD3_k127_4948189_0 ATPases associated with a variety of cellular activities K02056 - 3.6.3.17 3.372e-219 704.0
HKD3_k127_4948189_1 Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide K01426,K01455 - 3.5.1.4,3.5.1.49 3.68e-208 649.0
HKD3_k127_4948189_10 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000004834 199.0
HKD3_k127_4948189_11 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000002151 86.0
HKD3_k127_4948189_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 485.0
HKD3_k127_4948189_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 446.0
HKD3_k127_4948189_4 N-terminal TM domain of oligopeptide transport permease C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 416.0
HKD3_k127_4948189_5 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 397.0
HKD3_k127_4948189_6 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 370.0
HKD3_k127_4948189_7 GntR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 346.0
HKD3_k127_4948189_8 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 354.0
HKD3_k127_4948189_9 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 346.0
HKD3_k127_495087_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 2.753e-301 929.0
HKD3_k127_495087_1 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 553.0
HKD3_k127_495087_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 519.0
HKD3_k127_495087_3 Belongs to the ABC transporter superfamily K02032,K12372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005105 287.0
HKD3_k127_495087_4 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.000000000000000000000000000000000000000000000000000008043 190.0
HKD3_k127_495087_5 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000004174 130.0
HKD3_k127_4969425_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1097.0
HKD3_k127_4969425_1 TIGRFAM Phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000001594 220.0
HKD3_k127_4969425_2 Retinal pigment epithelial membrane protein K00464,K11159 - 1.13.11.75 0.000000000000000000000000000000000000000000000000000000000455 220.0
HKD3_k127_4976341_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 7.266e-226 708.0
HKD3_k127_4976341_1 COG3170 Tfp pilus assembly protein FimV K08086 - - 4.763e-211 683.0
HKD3_k127_4976341_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 1.459e-201 632.0
HKD3_k127_4976341_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 422.0
HKD3_k127_4976341_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 417.0
HKD3_k127_4976341_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 362.0
HKD3_k127_4976341_6 Entericidin EcnA/B family - - - 0.0000000000531 63.0
HKD3_k127_5020277_0 Putative diguanylate phosphodiesterase - - - 0.0 1033.0
HKD3_k127_5020277_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 8.853e-305 949.0
HKD3_k127_5020277_10 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 565.0
HKD3_k127_5020277_11 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 560.0
HKD3_k127_5020277_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 580.0
HKD3_k127_5020277_13 Diguanylate cyclase K13590 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 574.0
HKD3_k127_5020277_14 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01555 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 556.0
HKD3_k127_5020277_15 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 525.0
HKD3_k127_5020277_16 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 535.0
HKD3_k127_5020277_17 Belongs to the flagella basal body rod proteins family K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 487.0
HKD3_k127_5020277_18 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 491.0
HKD3_k127_5020277_19 Putative neutral zinc metallopeptidase K07054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 421.0
HKD3_k127_5020277_2 Tripartite tricarboxylate transporter TctA family K07793 - - 4.356e-274 850.0
HKD3_k127_5020277_20 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 424.0
HKD3_k127_5020277_21 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 383.0
HKD3_k127_5020277_22 flagellar basal-body rod protein K02392 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 400.0
HKD3_k127_5020277_23 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 379.0
HKD3_k127_5020277_24 TIGRFAM flagellar rod assembly protein muramidase FlgJ K02395 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 304.0
HKD3_k127_5020277_25 Belongs to the bacterial flagellin family K02397 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002865 280.0
HKD3_k127_5020277_26 Protein of unknown function (DUF962) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005874 242.0
HKD3_k127_5020277_27 response regulator K22010 - - 0.0000000000000000000000000000000000000000000000000000000000000007184 229.0
HKD3_k127_5020277_28 SapC - - - 0.00000000000000000000000000000000000000000000000000000000000004756 237.0
HKD3_k127_5020277_29 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000000000000000000000000000000004396 231.0
HKD3_k127_5020277_3 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 6.115e-274 858.0
HKD3_k127_5020277_30 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000006442 205.0
HKD3_k127_5020277_31 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000613 199.0
HKD3_k127_5020277_32 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000000000000166 187.0
HKD3_k127_5020277_33 - - - - 0.000000000000000000000000000000000000000000000008803 176.0
HKD3_k127_5020277_34 Protein of unknown function (DUF2783) - - - 0.000000000000000000001532 98.0
HKD3_k127_5020277_35 copG family - - - 0.000000000000000000002426 94.0
HKD3_k127_5020277_36 histidine kinase A domain protein - - - 0.00000000000000000001301 96.0
HKD3_k127_5020277_37 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000002188 91.0
HKD3_k127_5020277_38 cyclic nucleotide-binding - - - 0.00000000006321 67.0
HKD3_k127_5020277_4 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 8.826e-248 775.0
HKD3_k127_5020277_5 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 1.814e-244 767.0
HKD3_k127_5020277_6 CBS domain containing protein K03699 - - 5.477e-198 626.0
HKD3_k127_5020277_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 575.0
HKD3_k127_5020277_8 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 573.0
HKD3_k127_5020277_9 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 580.0
HKD3_k127_5038399_0 FtsX-like permease family K02004 - - 0.0 1018.0
HKD3_k127_5038399_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 534.0
HKD3_k127_5038399_10 Universal stress protein family - - - 0.00000000000000000000000000000000000000004403 158.0
HKD3_k127_5038399_11 Protein of unknown function (DUF805) - - - 0.0000000000000000000000000000000000004988 144.0
HKD3_k127_5038399_12 - - - - 0.00000000000000005932 85.0
HKD3_k127_5038399_2 coenzyme F390 synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008077 522.0
HKD3_k127_5038399_3 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 499.0
HKD3_k127_5038399_4 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 418.0
HKD3_k127_5038399_5 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 428.0
HKD3_k127_5038399_6 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 362.0
HKD3_k127_5038399_7 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008145 261.0
HKD3_k127_5038399_8 Nudix hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
HKD3_k127_5038399_9 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000116 198.0
HKD3_k127_5038922_0 ABC-type multidrug transport system, ATPase K06147,K18893 - - 4.455e-312 972.0
HKD3_k127_5038922_1 Phytoene dehydrogenase (Phytoene desaturase) K09835,K10027 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016119,GO:0016120,GO:0016491,GO:0016627,GO:0036094,GO:0042214,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046246,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 2.429e-252 787.0
HKD3_k127_5038922_10 Phytoene squalene synthetase K02291 GO:0003674,GO:0003824,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 375.0
HKD3_k127_5038922_11 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 359.0
HKD3_k127_5038922_12 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004715 259.0
HKD3_k127_5038922_13 PFAM GCN5-related N-acetyltransferase K02348 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007659 239.0
HKD3_k127_5038922_14 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000007048 202.0
HKD3_k127_5038922_15 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000106 166.0
HKD3_k127_5038922_16 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000004871 58.0
HKD3_k127_5038922_2 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 1.973e-227 724.0
HKD3_k127_5038922_3 PFAM extracellular solute-binding protein family 1 K17315 - - 1.575e-200 631.0
HKD3_k127_5038922_4 N-terminal domain of oxidoreductase K07119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 546.0
HKD3_k127_5038922_5 ATPases associated with a variety of cellular activities K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 510.0
HKD3_k127_5038922_6 Binding-protein-dependent transport system inner membrane component K17316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 482.0
HKD3_k127_5038922_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 466.0
HKD3_k127_5038922_8 Binding-protein-dependent transport system inner membrane component K17317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 464.0
HKD3_k127_5038922_9 KR domain K00046 - 1.1.1.69 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 407.0
HKD3_k127_5047261_0 Molecular chaperone. Has ATPase activity K04079 - - 0.0 1075.0
HKD3_k127_5047261_1 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 633.0
HKD3_k127_5047261_10 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 372.0
HKD3_k127_5047261_11 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 378.0
HKD3_k127_5047261_12 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 354.0
HKD3_k127_5047261_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 299.0
HKD3_k127_5047261_14 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003713 281.0
HKD3_k127_5047261_15 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000321 265.0
HKD3_k127_5047261_16 Belongs to the thiolase family K00632 - 2.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000008886 256.0
HKD3_k127_5047261_17 Uncharacterised protein family (UPF0093) K08973 - - 0.000000000000000000000000000000000000000000000000000000000000003263 222.0
HKD3_k127_5047261_18 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000006612 199.0
HKD3_k127_5047261_19 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000000000000000002938 204.0
HKD3_k127_5047261_2 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 557.0
HKD3_k127_5047261_20 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000000000000000003408 152.0
HKD3_k127_5047261_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005331 522.0
HKD3_k127_5047261_4 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 501.0
HKD3_k127_5047261_5 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 487.0
HKD3_k127_5047261_6 Amino-transferase class IV K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 470.0
HKD3_k127_5047261_7 KR domain K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 459.0
HKD3_k127_5047261_8 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 389.0
HKD3_k127_5047261_9 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 387.0
HKD3_k127_5063044_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1122.0
HKD3_k127_5063044_1 Insulinase (Peptidase family M16) K07263 - - 0.0 1091.0
HKD3_k127_5063044_10 Aldehyde dehydrogenase family K04072,K13922 - 1.1.1.1,1.2.1.10,1.2.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 542.0
HKD3_k127_5063044_11 homolog of phage Mu protein gp47 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 563.0
HKD3_k127_5063044_12 Phage tail sheath C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 553.0
HKD3_k127_5063044_13 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 535.0
HKD3_k127_5063044_14 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 499.0
HKD3_k127_5063044_15 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 495.0
HKD3_k127_5063044_16 PFAM extracellular solute-binding protein family 1 K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 423.0
HKD3_k127_5063044_17 leucine binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 444.0
HKD3_k127_5063044_18 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 398.0
HKD3_k127_5063044_19 Astacin (Peptidase family M12A) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 391.0
HKD3_k127_5063044_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 5.183e-280 870.0
HKD3_k127_5063044_20 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 386.0
HKD3_k127_5063044_21 Late control gene D protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 357.0
HKD3_k127_5063044_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 345.0
HKD3_k127_5063044_23 AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 349.0
HKD3_k127_5063044_24 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 342.0
HKD3_k127_5063044_25 ThiF family K22132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 345.0
HKD3_k127_5063044_26 Xylose isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006856 337.0
HKD3_k127_5063044_27 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009046 319.0
HKD3_k127_5063044_28 Baseplate assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 306.0
HKD3_k127_5063044_29 Protein of unknown function (DUF4255) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 306.0
HKD3_k127_5063044_3 cellulose binding - - - 6.618e-274 886.0
HKD3_k127_5063044_30 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 295.0
HKD3_k127_5063044_31 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004346 275.0
HKD3_k127_5063044_32 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
HKD3_k127_5063044_33 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004585 266.0
HKD3_k127_5063044_34 binding-protein-dependent transport systems inner membrane component K05773,K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000001675 257.0
HKD3_k127_5063044_35 Transcriptional regulator K02624 - - 0.00000000000000000000000000000000000000000000000000000000000000001486 250.0
HKD3_k127_5063044_36 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000000006449 208.0
HKD3_k127_5063044_37 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000001424 216.0
HKD3_k127_5063044_38 PFAM Diacylglycerol kinase, catalytic - - - 0.00000000000000000000000000000000000000000000000000009186 198.0
HKD3_k127_5063044_39 - - - - 0.0000000000000000000000000000000000000000000000000035 209.0
HKD3_k127_5063044_4 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 9.629e-235 740.0
HKD3_k127_5063044_40 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000000000000000002985 203.0
HKD3_k127_5063044_41 - - - - 0.00000000000000000000000000000000000003262 154.0
HKD3_k127_5063044_42 Gene 25-like lysozyme K06903 - - 0.0000000000000000000000000000000001017 141.0
HKD3_k127_5063044_44 - - - - 0.00000000000000000001266 102.0
HKD3_k127_5063044_46 PIN domain - - - 0.00000000002645 63.0
HKD3_k127_5063044_47 'PFAM Aminotransferase class I and II K09758 - 4.1.1.12 0.00000003367 59.0
HKD3_k127_5063044_49 - - - - 0.00000142 52.0
HKD3_k127_5063044_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 6.154e-233 752.0
HKD3_k127_5063044_50 cellulose binding - - - 0.00001898 55.0
HKD3_k127_5063044_52 Tetratricopeptide repeat - - - 0.00007566 55.0
HKD3_k127_5063044_6 homolog of phage Mu protein gp47 - - - 2.087e-226 739.0
HKD3_k127_5063044_7 Two component regulator propeller - - - 2.478e-207 679.0
HKD3_k127_5063044_8 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 601.0
HKD3_k127_5063044_9 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 548.0
HKD3_k127_5070296_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.275e-321 987.0
HKD3_k127_5070296_1 GTP-binding protein K06207 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 529.0
HKD3_k127_5070296_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 430.0
HKD3_k127_5070296_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000000000000000000000596 211.0
HKD3_k127_5114356_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1318.0
HKD3_k127_5114356_1 ammonium transporter K03320 - - 5.709e-229 723.0
HKD3_k127_5114356_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.921e-216 684.0
HKD3_k127_5114356_3 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000000000000000000000000000003442 216.0
HKD3_k127_5114356_4 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000003695 202.0
HKD3_k127_5114356_5 Cro/C1-type HTH DNA-binding domain - - - 0.00001719 46.0
HKD3_k127_5132920_0 PFAM AMP-dependent synthetase and ligase K01907 - 6.2.1.16 7.25e-261 831.0
HKD3_k127_5132920_1 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 607.0
HKD3_k127_5132920_2 ABC-type dipeptide transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 479.0
HKD3_k127_5132920_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000003159 199.0
HKD3_k127_5132920_4 Phosphate-selective porin O and P K07221 - - 0.0000000000000000000000000000000000002211 158.0
HKD3_k127_5133936_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 6.057e-255 810.0
HKD3_k127_5133936_1 PFAM sulfatase K01130 - 3.1.6.1 5.456e-209 653.0
HKD3_k127_5133936_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 306.0
HKD3_k127_5133936_3 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003808 244.0
HKD3_k127_5133936_4 intermediate-associated protein 30 - - - 0.00000000000000298 83.0
HKD3_k127_5139833_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1026.0
HKD3_k127_5139833_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 516.0
HKD3_k127_5139833_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 476.0
HKD3_k127_5139833_3 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000003209 248.0
HKD3_k127_5139833_4 Phospholipase D. Active site motifs. K06132 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008808,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0030572,GO:0032048,GO:0032049,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:0090483,GO:1901576 - 0.0000000000000000000000000000000000000000000006791 169.0
HKD3_k127_5174406_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1635.0
HKD3_k127_5174406_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 4.052e-290 905.0
HKD3_k127_5174406_10 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000008738 162.0
HKD3_k127_5174406_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.159e-288 896.0
HKD3_k127_5174406_3 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 3.587e-206 647.0
HKD3_k127_5174406_4 prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 419.0
HKD3_k127_5174406_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 395.0
HKD3_k127_5174406_6 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 292.0
HKD3_k127_5174406_7 HAD-hyrolase-like K22292 - 3.1.3.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001561 292.0
HKD3_k127_5174406_8 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.0000000000000000000000000000000000000000000000000000000000000000001898 245.0
HKD3_k127_5174406_9 Protein conserved in bacteria K09924 - - 0.000000000000000000000000000000000000000000000009476 198.0
HKD3_k127_5193674_0 ABC-type nitrate sulfonate bicarbonate transport K02051,K15576 - - 5.673e-232 742.0
HKD3_k127_5193674_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 601.0
HKD3_k127_5193674_10 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 416.0
HKD3_k127_5193674_11 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 339.0
HKD3_k127_5193674_12 monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005984 303.0
HKD3_k127_5193674_13 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000001535 195.0
HKD3_k127_5193674_14 Binding-protein-dependent transport system inner membrane component K15577 - - 0.000000000000000000000000000000000000000000000005326 194.0
HKD3_k127_5193674_15 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000001126 173.0
HKD3_k127_5193674_16 Di-iron-containing protein involved in the repair of iron-sulfur clusters K07322 - - 0.000000000000000000000000000000000000002179 151.0
HKD3_k127_5193674_17 DsrC like protein K11179 - - 0.00000000000000000000000000000000000008653 144.0
HKD3_k127_5193674_18 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000003036 50.0
HKD3_k127_5193674_2 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 561.0
HKD3_k127_5193674_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 554.0
HKD3_k127_5193674_4 Phosphonate ABC transporter K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 454.0
HKD3_k127_5193674_5 binding-protein-dependent transport systems inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 449.0
HKD3_k127_5193674_6 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 447.0
HKD3_k127_5193674_7 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 451.0
HKD3_k127_5193674_8 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 441.0
HKD3_k127_5193674_9 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 430.0
HKD3_k127_5197799_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 4.994e-204 645.0
HKD3_k127_5197799_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 497.0
HKD3_k127_5197799_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 331.0
HKD3_k127_5197799_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005877 271.0
HKD3_k127_5197799_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002352 254.0
HKD3_k127_5197799_5 Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000000599 232.0
HKD3_k127_5197799_6 Ribosomal-protein-alanine acetyltransferase K03789,K14742 - 2.3.1.128 0.000000000000000000000000000000000000000000000002399 197.0
HKD3_k127_5197799_7 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000001073 155.0
HKD3_k127_5197799_8 PQ loop repeat K15383 - - 0.000000000000000000000001403 120.0
HKD3_k127_5202611_0 The M ring may be actively involved in energy transduction K02409 - - 1.261e-229 725.0
HKD3_k127_5202611_1 flagellar motor switch protein K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 546.0
HKD3_k127_5202611_2 Flagellar protein export ATPase FliI K02412 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 328.0
HKD3_k127_5202611_3 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003642 252.0
HKD3_k127_5202611_4 flagellar assembly protein FliH K02411 - - 0.0000000000000000000000000000000000000000000000000000000000000004615 228.0
HKD3_k127_5202611_5 Flagellar protein FliT K02423 - - 0.000000000000000000000000000000000000002548 148.0
HKD3_k127_5202611_6 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000000000000000000411 143.0
HKD3_k127_521525_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1857.0
HKD3_k127_521525_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 534.0
HKD3_k127_521525_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 551.0
HKD3_k127_521525_3 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000006459 243.0
HKD3_k127_521525_4 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000004266 204.0
HKD3_k127_5267225_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.913e-315 969.0
HKD3_k127_5267225_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.3e-282 878.0
HKD3_k127_5267225_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 6.174e-247 766.0
HKD3_k127_5267225_3 Cys/Met metabolism PLP-dependent enzyme K01760 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 591.0
HKD3_k127_5267225_4 Sugar (and other) transporter K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 559.0
HKD3_k127_5267225_5 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002989 295.0
HKD3_k127_5267225_6 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000003948 237.0
HKD3_k127_5267225_7 cyclase dehydrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001589 237.0
HKD3_k127_5267225_8 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000005478 138.0
HKD3_k127_5267225_9 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000001109 96.0
HKD3_k127_5270034_0 Belongs to the UPF0061 (SELO) family - - - 7.319e-233 730.0
HKD3_k127_5270034_1 PFAM FAD dependent oxidoreductase K00285 - 1.4.5.1 2.452e-224 703.0
HKD3_k127_5270034_10 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 370.0
HKD3_k127_5270034_11 Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 364.0
HKD3_k127_5270034_12 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 359.0
HKD3_k127_5270034_13 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 359.0
HKD3_k127_5270034_14 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005377 353.0
HKD3_k127_5270034_15 ATPase MipZ K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008893 325.0
HKD3_k127_5270034_16 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 321.0
HKD3_k127_5270034_17 extra-cytoplasmic solute receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 338.0
HKD3_k127_5270034_18 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006407 274.0
HKD3_k127_5270034_19 Protein of unknown function (DUF3717) K06938 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002259 258.0
HKD3_k127_5270034_2 permease K07089 - - 2.768e-208 657.0
HKD3_k127_5270034_20 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002159 262.0
HKD3_k127_5270034_21 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000009699 269.0
HKD3_k127_5270034_22 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000000000000003556 215.0
HKD3_k127_5270034_23 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000009111 182.0
HKD3_k127_5270034_24 Transcriptional regulator K03892 - - 0.000000000000000000000000000000000000000007163 163.0
HKD3_k127_5270034_25 Heavy-metal resistance - - - 0.00000000000000000000000000005683 125.0
HKD3_k127_5270034_26 Thioredoxin domain - - - 0.000000000000000000000000002013 129.0
HKD3_k127_5270034_27 - - - - 0.00000000000000000000000006133 113.0
HKD3_k127_5270034_28 Alpha/beta hydrolase family - - - 0.00000000000000000003371 103.0
HKD3_k127_5270034_29 - - - - 0.0000000000000003503 88.0
HKD3_k127_5270034_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 8.191e-195 610.0
HKD3_k127_5270034_4 major facilitator superfamily - - - 1.321e-194 637.0
HKD3_k127_5270034_5 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008899 574.0
HKD3_k127_5270034_6 PFAM Peptidase M20 K01451 - 3.5.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 565.0
HKD3_k127_5270034_7 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 571.0
HKD3_k127_5270034_8 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 504.0
HKD3_k127_5270034_9 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 421.0
HKD3_k127_5287878_0 FtsX-like permease family K02004 - - 0.0 1191.0
HKD3_k127_5287878_1 ABC-type dipeptide transport system, periplasmic component K02035 - - 4.539e-280 870.0
HKD3_k127_5287878_10 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006271 243.0
HKD3_k127_5287878_11 histidine kinase HAMP region domain protein K03406,K03776,K05874 - - 0.0000000000000000000000001832 107.0
HKD3_k127_5287878_12 mercury ion transmembrane transporter activity K07089,K07213 - - 0.000000000000000000000003154 106.0
HKD3_k127_5287878_2 Amidohydrolase family - - - 1.405e-244 769.0
HKD3_k127_5287878_3 methyl-accepting chemotaxis protein K03406 - - 5.754e-233 728.0
HKD3_k127_5287878_4 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 7.738e-205 653.0
HKD3_k127_5287878_5 PFAM ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 463.0
HKD3_k127_5287878_6 Von Willebrand factor A K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 437.0
HKD3_k127_5287878_7 Cytochrome c class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 304.0
HKD3_k127_5287878_8 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 294.0
HKD3_k127_5287878_9 PFAM phospholipase A1 K01058 - 3.1.1.32,3.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002776 273.0
HKD3_k127_5288912_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1257.0
HKD3_k127_5288912_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.157e-304 962.0
HKD3_k127_5288912_10 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 348.0
HKD3_k127_5288912_11 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 305.0
HKD3_k127_5288912_12 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000052 286.0
HKD3_k127_5288912_13 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005705 285.0
HKD3_k127_5288912_2 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.823e-226 710.0
HKD3_k127_5288912_3 Tfp pilus assembly protein FimV - - - 2.245e-208 665.0
HKD3_k127_5288912_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 2.785e-206 656.0
HKD3_k127_5288912_5 Cobalamin synthesis protein - - - 1.073e-198 623.0
HKD3_k127_5288912_6 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 574.0
HKD3_k127_5288912_7 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009568 436.0
HKD3_k127_5288912_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 409.0
HKD3_k127_5288912_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 389.0
HKD3_k127_5290992_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 4.159e-314 1017.0
HKD3_k127_5290992_1 Sulfite reductase K00381,K00392 - 1.8.1.2,1.8.7.1 1.617e-288 894.0
HKD3_k127_5290992_10 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 371.0
HKD3_k127_5290992_11 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 334.0
HKD3_k127_5290992_12 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 340.0
HKD3_k127_5290992_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 310.0
HKD3_k127_5290992_14 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002303 292.0
HKD3_k127_5290992_15 Bacterial protein of unknown function (DUF934) - - - 0.00000000000000000000000000000000000000000000000000000000000000003958 229.0
HKD3_k127_5290992_16 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000000003298 208.0
HKD3_k127_5290992_17 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000008585 214.0
HKD3_k127_5290992_2 HDOD domain - - - 4.244e-274 867.0
HKD3_k127_5290992_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.057e-253 789.0
HKD3_k127_5290992_4 TonB dependent receptor K02014 - - 1.744e-235 750.0
HKD3_k127_5290992_5 Ferredoxin--NADP reductase K00384 - 1.8.1.9 8.524e-220 684.0
HKD3_k127_5290992_6 associated with various cellular activities - - - 4.607e-195 616.0
HKD3_k127_5290992_7 HDOD domain K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 626.0
HKD3_k127_5290992_8 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 597.0
HKD3_k127_5290992_9 VWA-like domain (DUF2201) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 520.0
HKD3_k127_5301288_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.649e-306 945.0
HKD3_k127_5301288_1 Major facilitator Superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 610.0
HKD3_k127_5301288_10 Short C-terminal domain K08982 - - 0.000000000000001567 79.0
HKD3_k127_5301288_11 LTXXQ motif family protein - - - 0.00000000000008643 79.0
HKD3_k127_5301288_2 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 467.0
HKD3_k127_5301288_3 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 419.0
HKD3_k127_5301288_4 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 407.0
HKD3_k127_5301288_5 Belongs to the GST superfamily K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000582 348.0
HKD3_k127_5301288_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 332.0
HKD3_k127_5301288_7 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 314.0
HKD3_k127_5301288_8 Thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003966 239.0
HKD3_k127_5301288_9 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000001034 141.0
HKD3_k127_5305956_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0 1157.0
HKD3_k127_5305956_1 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.104e-229 732.0
HKD3_k127_5305956_10 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 583.0
HKD3_k127_5305956_11 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 524.0
HKD3_k127_5305956_12 Permease, YjgP YjgQ K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 504.0
HKD3_k127_5305956_13 PFAM Alcohol dehydrogenase zinc-binding domain protein K19745 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 501.0
HKD3_k127_5305956_14 transcriptional regulator K13634,K13635 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 485.0
HKD3_k127_5305956_15 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 472.0
HKD3_k127_5305956_16 Permease, YjgP YjgQ K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 478.0
HKD3_k127_5305956_17 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 451.0
HKD3_k127_5305956_18 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 446.0
HKD3_k127_5305956_19 Class II aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 396.0
HKD3_k127_5305956_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 5.447e-212 668.0
HKD3_k127_5305956_20 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 374.0
HKD3_k127_5305956_21 PFAM Cyclic nucleotide-binding K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 364.0
HKD3_k127_5305956_22 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 364.0
HKD3_k127_5305956_23 Protein of unknown function (DUF808) K09781 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 370.0
HKD3_k127_5305956_24 LysR substrate binding domain K05596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 349.0
HKD3_k127_5305956_25 4Fe-4S dicluster domain K05796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 334.0
HKD3_k127_5305956_26 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 317.0
HKD3_k127_5305956_27 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 298.0
HKD3_k127_5305956_28 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
HKD3_k127_5305956_29 Lysine exporter protein (Lyse ygga) K06895 - - 0.000000000000000000000000000000000000000000000000000000000000001553 225.0
HKD3_k127_5305956_3 PFAM Aminotransferase class I and II K14287 - 2.6.1.88 6.372e-211 659.0
HKD3_k127_5305956_30 Tfp pilus assembly protein FimV - - - 0.00000000000000000000000000000000000000000000007963 193.0
HKD3_k127_5305956_31 Cell wall-associated K13695,K19303 - - 0.000000000000000000000000000000000000000000001195 173.0
HKD3_k127_5305956_32 - - - - 0.0000000000000000000000000000000000000002491 160.0
HKD3_k127_5305956_33 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000000002628 151.0
HKD3_k127_5305956_34 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000004937 150.0
HKD3_k127_5305956_35 PFAM thiamineS protein - - - 0.000000000000000000000000000000000006378 141.0
HKD3_k127_5305956_36 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000000000000000009173 147.0
HKD3_k127_5305956_37 CbiX K03795 - 4.99.1.3 0.00000000000000000000000000000000001601 153.0
HKD3_k127_5305956_38 - - - - 0.000000000000000000000000001293 122.0
HKD3_k127_5305956_4 Pyridine nucleotide-disulphide oxidoreductase - - - 6.308e-209 656.0
HKD3_k127_5305956_40 - - - - 0.000000000000000002075 99.0
HKD3_k127_5305956_41 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08939 - - 0.00000000000000006683 83.0
HKD3_k127_5305956_42 Antenna complexes are light-harvesting systems, which transfer the excitation energy to the reaction centers K08930 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000167 75.0
HKD3_k127_5305956_43 - - - - 0.0002515 52.0
HKD3_k127_5305956_44 - - - - 0.0006191 46.0
HKD3_k127_5305956_5 Belongs to the thiolase family K00626 - 2.3.1.9 2.249e-204 641.0
HKD3_k127_5305956_6 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 2.501e-201 642.0
HKD3_k127_5305956_7 Aminoglycoside phosphotransferase - - - 9.858e-200 625.0
HKD3_k127_5305956_8 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 610.0
HKD3_k127_5305956_9 PUCC protein K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 589.0
HKD3_k127_5348873_0 regulation of DNA-templated transcription, elongation - - - 2.122e-271 861.0
HKD3_k127_5348873_1 Protein of unknown function (DUF1254) - - - 5.408e-235 737.0
HKD3_k127_5348873_10 MATE efflux family protein - - - 0.0000000000000000000006795 111.0
HKD3_k127_5348873_11 - - - - 0.00000000000000000002558 96.0
HKD3_k127_5348873_12 helix_turn_helix, Lux Regulon - - - 0.00000000005893 76.0
HKD3_k127_5348873_13 Cyclic nucleotide-monophosphate binding domain - - - 0.0000001766 56.0
HKD3_k127_5348873_2 Belongs to the glycosyl hydrolase 13 family K01187 - 3.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 469.0
HKD3_k127_5348873_3 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 443.0
HKD3_k127_5348873_4 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 379.0
HKD3_k127_5348873_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009405 351.0
HKD3_k127_5348873_6 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008268 258.0
HKD3_k127_5348873_7 transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000007644 242.0
HKD3_k127_5348873_8 Outer membrane lipoprotein K06077 - - 0.0000000000000000000000000000000000000000000000000000005542 201.0
HKD3_k127_5348873_9 Outer Membrane Lipoprotein K06077 - - 0.00000000000000000000000000000000000000000000004848 174.0
HKD3_k127_5365813_0 Likely ribonuclease with RNase H fold. K06959 - - 0.0 1202.0
HKD3_k127_5365813_1 Nitrogenase component 1 type Oxidoreductase K11334 - 1.3.7.14,1.3.7.15 1.153e-253 808.0
HKD3_k127_5365813_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 365.0
HKD3_k127_5365813_11 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 366.0
HKD3_k127_5365813_12 Belongs to the anaerobic coproporphyrinogen-III oxidase family K02495 - 1.3.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 359.0
HKD3_k127_5365813_13 TIGRFAM chlorophyllide reductase subunit Z K11335 - 1.3.7.14,1.3.7.15 0.0000000000000000000000000000000000009007 141.0
HKD3_k127_5365813_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03669 - - 1.591e-238 784.0
HKD3_k127_5365813_3 Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs) K03670 - - 4.187e-206 661.0
HKD3_k127_5365813_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.911e-196 617.0
HKD3_k127_5365813_5 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 606.0
HKD3_k127_5365813_6 AAA domain K11333 - 1.3.7.14,1.3.7.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 586.0
HKD3_k127_5365813_7 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 530.0
HKD3_k127_5365813_8 Esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 505.0
HKD3_k127_5365813_9 Dehydrogenase K11337 - 1.1.1.396 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 471.0
HKD3_k127_5433049_0 RNB K01147 - 3.1.13.1 0.0 1047.0
HKD3_k127_5433049_1 Biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 5.917e-275 849.0
HKD3_k127_5433049_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001414 234.0
HKD3_k127_5433049_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000002855 222.0
HKD3_k127_5433049_12 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000000000000000006201 208.0
HKD3_k127_5433049_13 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000000000000000008425 194.0
HKD3_k127_5433049_14 TIGRFAM MJ0042 family finger-like - - - 0.0000000000000000000000000000000000000000000000000002165 201.0
HKD3_k127_5433049_15 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000001328 173.0
HKD3_k127_5433049_16 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000000000000009304 166.0
HKD3_k127_5433049_17 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000000000001191 151.0
HKD3_k127_5433049_18 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000002475 139.0
HKD3_k127_5433049_19 - K11275 - - 0.000000000000000000000000000005751 123.0
HKD3_k127_5433049_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 537.0
HKD3_k127_5433049_20 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000003652 95.0
HKD3_k127_5433049_21 Belongs to the UPF0235 family K09131 - - 0.00000000000000009031 89.0
HKD3_k127_5433049_3 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 490.0
HKD3_k127_5433049_4 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 419.0
HKD3_k127_5433049_5 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 398.0
HKD3_k127_5433049_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 358.0
HKD3_k127_5433049_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 366.0
HKD3_k127_5433049_8 Sulfatase-modifying factor enzyme 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 320.0
HKD3_k127_5433049_9 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 312.0
HKD3_k127_5440087_0 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 1.364e-243 760.0
HKD3_k127_5440087_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 6.686e-217 681.0
HKD3_k127_5440087_2 Nitrile hydratase K01721 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 342.0
HKD3_k127_5440087_3 NHase catalyzes the hydration of various nitrile compounds to the corresponding amides K20807 - 4.2.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 297.0
HKD3_k127_5440087_4 AAA domain (dynein-related subfamily) K03924 - - 0.0000000000000000000000000000000000000000000000000000000004223 210.0
HKD3_k127_5440087_5 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000003157 169.0
HKD3_k127_5440087_6 Nitrile hydratase beta subunit - - - 0.00000000000000000000000000000000000242 153.0
HKD3_k127_5460817_0 PrkA AAA domain K07180 - - 0.0 1194.0
HKD3_k127_5460817_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1132.0
HKD3_k127_5460817_10 HlyD family secretion protein K13408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 451.0
HKD3_k127_5460817_11 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 430.0
HKD3_k127_5460817_12 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 418.0
HKD3_k127_5460817_13 Binding-protein-dependent transport system inner membrane component K02053 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0016020,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071705,GO:0071944,GO:0098657 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 383.0
HKD3_k127_5460817_14 phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 337.0
HKD3_k127_5460817_15 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 334.0
HKD3_k127_5460817_16 regulatory protein Crp K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 323.0
HKD3_k127_5460817_17 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 299.0
HKD3_k127_5460817_18 Lysine exporter protein (Lyse ygga) K11250 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 295.0
HKD3_k127_5460817_19 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000002825 269.0
HKD3_k127_5460817_2 Peptidase C39 family K13409 - - 0.0 1036.0
HKD3_k127_5460817_20 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000000000000000000000000000002204 232.0
HKD3_k127_5460817_21 Fe-S-cluster oxidoreductase K06940 - - 0.0000000000000000000000000000004034 126.0
HKD3_k127_5460817_22 Protein of unknown function (DUF2892) - - - 0.000000000000000000000002156 107.0
HKD3_k127_5460817_23 Predicted membrane protein (DUF2061) - - - 0.0000000000000000000172 99.0
HKD3_k127_5460817_3 belongs to the aldehyde dehydrogenase family K00137 - 1.2.1.19 6.246e-265 821.0
HKD3_k127_5460817_4 SpoVR family K06415 - - 7.437e-226 730.0
HKD3_k127_5460817_5 Bacterial extracellular solute-binding protein K02055 - - 1.146e-215 677.0
HKD3_k127_5460817_6 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 516.0
HKD3_k127_5460817_7 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 489.0
HKD3_k127_5460817_8 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 467.0
HKD3_k127_5460817_9 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009091 459.0
HKD3_k127_549364_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1532.0
HKD3_k127_549364_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 7.173e-318 995.0
HKD3_k127_549364_10 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000476 308.0
HKD3_k127_549364_11 AAA domain K07505 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001159 283.0
HKD3_k127_549364_12 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004424 259.0
HKD3_k127_549364_13 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000005268 248.0
HKD3_k127_549364_14 PFAM Restriction endonuclease K07448 - - 0.0000000000000000000000000000000000000000000000000000000000000000002317 240.0
HKD3_k127_549364_15 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000122 214.0
HKD3_k127_549364_16 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000000002948 192.0
HKD3_k127_549364_17 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000006413 198.0
HKD3_k127_549364_18 Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction - - - 0.000000000000000000000000000000000000000000000003158 179.0
HKD3_k127_549364_19 PFAM Cytochrome c, class I K08738 - - 0.0000000000000000000000000000000000001234 149.0
HKD3_k127_549364_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.398e-312 967.0
HKD3_k127_549364_20 enzyme of the cupin superfamily K06995 - - 0.000000000000000000000000000008783 132.0
HKD3_k127_549364_21 - - - - 0.00000000000000000000002322 108.0
HKD3_k127_549364_22 DNA packaging K07474 - - 0.000000000000002899 82.0
HKD3_k127_549364_23 - - - - 0.000000000002403 72.0
HKD3_k127_549364_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 3.471e-207 661.0
HKD3_k127_549364_4 lytic transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 601.0
HKD3_k127_549364_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009925 569.0
HKD3_k127_549364_6 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 452.0
HKD3_k127_549364_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 446.0
HKD3_k127_549364_8 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 361.0
HKD3_k127_549364_9 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 351.0
HKD3_k127_5508438_0 Domain of unknown function (DUF3479) K03403 - 6.6.1.1 0.0 1785.0
HKD3_k127_5508438_1 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04039 - 1.3.7.7 1.344e-279 868.0
HKD3_k127_5508438_10 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007947 520.0
HKD3_k127_5508438_11 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007534 386.0
HKD3_k127_5508438_12 Photosynthetic reaction centre, H-chain N-terminal region K13991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 321.0
HKD3_k127_5508438_13 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 319.0
HKD3_k127_5508438_14 Magnesium-protoporphyrin IX methyltransferase C-terminus K03428 - 2.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006711 323.0
HKD3_k127_5508438_15 Protein of unknown function (DUF3623) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 310.0
HKD3_k127_5508438_16 Bacterial PH domain - - - 0.000000000000000000000000000000000000000000000000000000000007343 214.0
HKD3_k127_5508438_17 Photosynthetic complex assembly protein - - - 0.0000000000000000000000000000001218 133.0
HKD3_k127_5508438_18 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000003583 51.0
HKD3_k127_5508438_2 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 1.135e-213 668.0
HKD3_k127_5508438_3 Exonuclease C-terminal K01141 - 3.1.11.1 7.564e-213 670.0
HKD3_k127_5508438_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 606.0
HKD3_k127_5508438_5 Photosynthetic complex (LH1) assembly protein LhaA K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006862 619.0
HKD3_k127_5508438_6 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 594.0
HKD3_k127_5508438_7 Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K04035 - 1.14.13.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005879 571.0
HKD3_k127_5508438_8 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007311 569.0
HKD3_k127_5508438_9 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 507.0
HKD3_k127_5616578_0 NADPH-dependent glutamate synthase beta - - - 0.0 1120.0
HKD3_k127_5616578_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 8.543e-247 766.0
HKD3_k127_5616578_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 500.0
HKD3_k127_5616578_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 388.0
HKD3_k127_5616578_4 Fe-S oxidoreductase K21834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001512 244.0
HKD3_k127_5616578_5 - - - - 0.00000000000000000000000001018 124.0
HKD3_k127_5616578_6 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000008016 87.0
HKD3_k127_5741936_0 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 3.192e-228 714.0
HKD3_k127_5741936_1 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 3.596e-203 633.0
HKD3_k127_5741936_2 Transketolase, C-terminal domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 598.0
HKD3_k127_5741936_3 ATP-NAD kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002312 278.0
HKD3_k127_5741936_4 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000004199 222.0
HKD3_k127_5741936_5 Biotin-requiring enzyme - - - 0.0000000000000000000007121 98.0
HKD3_k127_5793920_0 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 6.803e-266 822.0
HKD3_k127_5793920_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 2.793e-238 736.0
HKD3_k127_5793920_10 sulfur relay protein TusD DsrE K07235 - - 0.0000000000000000000000000000000000000000000000000000000000000000003048 229.0
HKD3_k127_5793920_11 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000000000000000000004864 205.0
HKD3_k127_5793920_12 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000002185 204.0
HKD3_k127_5793920_13 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000007047 202.0
HKD3_k127_5793920_14 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000001497 181.0
HKD3_k127_5793920_15 Peptidase S24-like - - - 0.000000000000000000000000000000000000001093 165.0
HKD3_k127_5793920_16 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000000007916 145.0
HKD3_k127_5793920_17 DsrH like protein K07237 - - 0.00000000000000000000000000000009697 130.0
HKD3_k127_5793920_18 - - - - 0.0000000000000000000000001033 117.0
HKD3_k127_5793920_19 - - - - 0.000000000000000000003927 100.0
HKD3_k127_5793920_2 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 1.704e-228 730.0
HKD3_k127_5793920_20 - - - - 0.000000000004723 74.0
HKD3_k127_5793920_3 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 544.0
HKD3_k127_5793920_4 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009919 412.0
HKD3_k127_5793920_5 Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 285.0
HKD3_k127_5793920_6 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000839 268.0
HKD3_k127_5793920_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002725 266.0
HKD3_k127_5793920_8 Cas6 Crispr - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007255 265.0
HKD3_k127_5793920_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001649 256.0
HKD3_k127_593348_0 Glutaminase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 515.0
HKD3_k127_593348_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 404.0
HKD3_k127_593348_2 Transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 342.0
HKD3_k127_593348_3 Transcriptional regulatory protein, C terminal K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000824 294.0
HKD3_k127_593348_4 long-chain fatty acid transport protein - - - 0.000111 51.0
HKD3_k127_59989_0 PFAM TrkA-N domain protein K03499 - - 4.521e-221 697.0
HKD3_k127_59989_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.011e-207 680.0
HKD3_k127_59989_10 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000007071 142.0
HKD3_k127_59989_2 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 555.0
HKD3_k127_59989_3 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 495.0
HKD3_k127_59989_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 440.0
HKD3_k127_59989_5 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 366.0
HKD3_k127_59989_6 PFAM class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007424 318.0
HKD3_k127_59989_7 membrane - - - 0.00000000000000000000000000000000000000000000000000003266 195.0
HKD3_k127_59989_8 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.00000000000000000000000000000000000002122 145.0
HKD3_k127_59989_9 PEP-CTERM motif - - - 0.00000000000000000000000000000000002539 144.0
HKD3_k127_6078333_0 Patatin-like phospholipase K07001 - - 3.737e-228 732.0
HKD3_k127_6078333_1 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 578.0
HKD3_k127_6078333_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 416.0
HKD3_k127_6078333_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 417.0
HKD3_k127_6078333_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 335.0
HKD3_k127_6078333_5 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001955 261.0
HKD3_k127_6099825_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 8.42e-200 637.0
HKD3_k127_6099825_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 450.0
HKD3_k127_6099825_2 MerR, DNA binding - - - 0.0000000000000000000000000000000000000000000000000006917 187.0
HKD3_k127_6099825_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000008732 198.0
HKD3_k127_61230_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K11711 - 2.7.13.3 1.373e-252 797.0
HKD3_k127_61230_1 Malic enzyme K00029 - 1.1.1.40 7.701e-233 732.0
HKD3_k127_61230_2 Transmembrane secretion effector - - - 1.982e-212 672.0
HKD3_k127_61230_3 Oxidoreductase domain protein - - - 2.506e-205 641.0
HKD3_k127_61230_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 443.0
HKD3_k127_61230_5 helix_turn_helix, Lux Regulon K11712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 305.0
HKD3_k127_61230_6 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000001329 250.0
HKD3_k127_61230_7 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000111 209.0
HKD3_k127_61230_8 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000002935 189.0
HKD3_k127_61230_9 gag-polyprotein putative aspartyl protease - - - 0.00000002608 68.0
HKD3_k127_6128007_0 Circularly permuted ATP-grasp type 2 - - - 8.785e-273 844.0
HKD3_k127_6128007_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 8.134e-228 714.0
HKD3_k127_6128007_10 peptidase K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 337.0
HKD3_k127_6128007_11 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 327.0
HKD3_k127_6128007_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 330.0
HKD3_k127_6128007_13 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 336.0
HKD3_k127_6128007_14 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002061 283.0
HKD3_k127_6128007_15 Haem-degrading K11477 - - 0.000000000000000000000000000000000000000000000000000000000002112 213.0
HKD3_k127_6128007_16 Involved in the tonB-independent uptake of proteins - - - 0.000000000000005388 78.0
HKD3_k127_6128007_2 Belongs to the CarA family K01956 - 6.3.5.5 3.569e-206 648.0
HKD3_k127_6128007_3 Histidine kinase-like ATPases - - - 1.489e-200 648.0
HKD3_k127_6128007_4 Belongs to the CarB family K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 551.0
HKD3_k127_6128007_5 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 547.0
HKD3_k127_6128007_6 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 505.0
HKD3_k127_6128007_7 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 409.0
HKD3_k127_6128007_8 PFAM EAL domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 377.0
HKD3_k127_6128007_9 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 388.0
HKD3_k127_6157290_0 DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 620.0
HKD3_k127_6157290_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 527.0
HKD3_k127_6157290_2 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K01555 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 522.0
HKD3_k127_6157290_3 D-isomer specific 2-hydroxyacid dehydrogenase K00090 - 1.1.1.215,1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 503.0
HKD3_k127_6157290_4 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 490.0
HKD3_k127_6157290_5 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 375.0
HKD3_k127_6157290_6 TIGRFAM phasin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004814 259.0
HKD3_k127_6157290_7 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005141 239.0
HKD3_k127_6157290_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000002104 203.0
HKD3_k127_6157290_9 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000000002489 175.0
HKD3_k127_61593_0 UPF0313 protein - - - 5.193e-255 792.0
HKD3_k127_61593_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 8.361e-206 647.0
HKD3_k127_61593_2 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 439.0
HKD3_k127_61593_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000002938 138.0
HKD3_k127_6162899_0 Sigma-54 interaction domain K02584 - - 3.184e-235 759.0
HKD3_k127_6162899_1 Site-specific recombinase - - - 7.854e-234 742.0
HKD3_k127_6162899_10 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 314.0
HKD3_k127_6162899_11 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003525 271.0
HKD3_k127_6162899_12 ApaG domain K06195 - - 0.000000000000000000000000000000000000000000000000003751 186.0
HKD3_k127_6162899_13 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000000000001069 171.0
HKD3_k127_6162899_14 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000001407 91.0
HKD3_k127_6162899_2 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 614.0
HKD3_k127_6162899_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 569.0
HKD3_k127_6162899_4 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 539.0
HKD3_k127_6162899_5 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 518.0
HKD3_k127_6162899_6 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 501.0
HKD3_k127_6162899_7 ATPases associated with a variety of cellular activities K02049,K15578 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005624 496.0
HKD3_k127_6162899_8 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 440.0
HKD3_k127_6162899_9 Binding-protein-dependent transport system inner membrane component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 337.0
HKD3_k127_6181121_0 PFAM Type II secretion system protein E K02454,K02652,K12276 - - 1.611e-233 736.0
HKD3_k127_6181121_1 type II secretion system K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006772 258.0
HKD3_k127_6181121_10 - - - - 0.00000001239 62.0
HKD3_k127_6181121_2 PFAM Fimbrial assembly family protein K02461 - - 0.00000000000000000000000000000000000000000000000000000000000000000000414 247.0
HKD3_k127_6181121_3 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000000000000000001468 196.0
HKD3_k127_6181121_4 type II secretion system protein K K02460 - - 0.00000000000000000000000000000000000000000000000000006801 208.0
HKD3_k127_6181121_5 Pfam:N_methyl_2 K02459 - - 0.000000000000000000000000000000000000000001815 171.0
HKD3_k127_6181121_6 TIGRFAM general secretion pathway protein H K02457 - - 0.0000000000000000000000000000000000000003812 156.0
HKD3_k127_6181121_7 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.000000000000000000000000000000000001026 147.0
HKD3_k127_6181121_8 Prokaryotic N-terminal methylation motif K02458 - - 0.00000000000000000000001944 111.0
HKD3_k127_6181121_9 Polysaccharide biosynthesis protein - - - 0.000000000000001522 79.0
HKD3_k127_6189986_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.678e-234 728.0
HKD3_k127_6189986_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 457.0
HKD3_k127_6189986_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 377.0
HKD3_k127_6189986_3 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 363.0
HKD3_k127_6189986_4 Domain of unknown function (DUF4397) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000876 287.0
HKD3_k127_6189986_5 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009412 267.0
HKD3_k127_6189986_6 Haem-degrading - - - 0.000000000000000000000000000000000000000000006725 185.0
HKD3_k127_6189986_7 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000005376 171.0
HKD3_k127_6210502_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1546.0
HKD3_k127_6210502_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 4.058e-267 830.0
HKD3_k127_6210502_2 Urea ABC transporter, urea binding protein K11959 - - 2.275e-240 747.0
HKD3_k127_6210502_3 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 471.0
HKD3_k127_6210502_4 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000000000000005151 217.0
HKD3_k127_6210502_5 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000000000001678 186.0
HKD3_k127_6210502_6 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.000000000000000000000000000000000000000000000000008798 186.0
HKD3_k127_6210502_7 Uncharacterized protein conserved in bacteria (DUF2242) - - - 0.00000000000000000000000000000000000000000003711 170.0
HKD3_k127_6212236_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1702.0
HKD3_k127_6212236_1 TIGRFAM glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1106.0
HKD3_k127_6212236_10 pyrroloquinoline quinone binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001495 273.0
HKD3_k127_6212236_11 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000003659 244.0
HKD3_k127_6212236_12 phenylacetic acid degradation protein PaaD K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000000000000000000000000000000000000004968 238.0
HKD3_k127_6212236_13 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000000000000000000000000000403 229.0
HKD3_k127_6212236_14 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000001641 227.0
HKD3_k127_6212236_15 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000000002316 219.0
HKD3_k127_6212236_16 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000000000001472 187.0
HKD3_k127_6212236_17 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000007625 191.0
HKD3_k127_6212236_18 Helix-hairpin-helix motif K02237 - - 0.0000000000000000000000001023 113.0
HKD3_k127_6212236_19 - - - - 0.00000000000003244 76.0
HKD3_k127_6212236_2 Bacterial protein of unknown function (DUF853) K06915 - - 8.024e-263 817.0
HKD3_k127_6212236_3 ribonuclease, Rne Rng family K08301 - - 1.304e-251 786.0
HKD3_k127_6212236_4 Belongs to the GARS family K01945 - 6.3.4.13 4.609e-212 668.0
HKD3_k127_6212236_5 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 534.0
HKD3_k127_6212236_6 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 424.0
HKD3_k127_6212236_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 422.0
HKD3_k127_6212236_8 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 332.0
HKD3_k127_6212236_9 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 321.0
HKD3_k127_6242172_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1262.0
HKD3_k127_6242172_1 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 447.0
HKD3_k127_6242172_2 Belongs to the UPF0246 family K09861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003627 379.0
HKD3_k127_6242172_3 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 334.0
HKD3_k127_6242172_4 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 253.0
HKD3_k127_6242172_5 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000006689 226.0
HKD3_k127_6242172_6 Phospholipase/Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000365 219.0
HKD3_k127_6242172_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000001801 195.0
HKD3_k127_6246668_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 0.0 1201.0
HKD3_k127_6246668_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1026.0
HKD3_k127_6246668_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 522.0
HKD3_k127_6246668_11 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 483.0
HKD3_k127_6246668_12 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 433.0
HKD3_k127_6246668_13 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 436.0
HKD3_k127_6246668_14 cell septum assembly - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003412 417.0
HKD3_k127_6246668_15 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007386 395.0
HKD3_k127_6246668_16 hydrolase activity, acting on ester bonds K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 395.0
HKD3_k127_6246668_17 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 387.0
HKD3_k127_6246668_18 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 362.0
HKD3_k127_6246668_19 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 350.0
HKD3_k127_6246668_2 Acetyl-CoA dehydrogenase C-terminal like K00248 - 1.3.8.1 0.0 1021.0
HKD3_k127_6246668_20 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 314.0
HKD3_k127_6246668_21 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000576 350.0
HKD3_k127_6246668_22 GDSL-like Lipase/Acylhydrolase family K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 304.0
HKD3_k127_6246668_23 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001393 233.0
HKD3_k127_6246668_24 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000000000000000000002575 188.0
HKD3_k127_6246668_25 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000003231 165.0
HKD3_k127_6246668_26 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000003028 183.0
HKD3_k127_6246668_27 - - - - 0.00000000000000000000000000000001041 143.0
HKD3_k127_6246668_28 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000009049 111.0
HKD3_k127_6246668_3 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 2.807e-303 938.0
HKD3_k127_6246668_4 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.415e-269 842.0
HKD3_k127_6246668_5 AMP-binding enzyme - - - 1.449e-265 829.0
HKD3_k127_6246668_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 2.391e-226 709.0
HKD3_k127_6246668_7 amino acid K01999 - - 1.181e-218 686.0
HKD3_k127_6246668_8 Belongs to the thiolase family K00626 - 2.3.1.9 5.205e-217 679.0
HKD3_k127_6246668_9 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 575.0
HKD3_k127_6266626_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1217.0
HKD3_k127_6266626_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 9.623e-243 769.0
HKD3_k127_6266626_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007616 286.0
HKD3_k127_6266626_3 Maltoporin (phage lambda and maltose receptor) K02024 - - 0.000000000000000000000000000007015 124.0
HKD3_k127_6327126_0 Phosphate acetyl butaryl transferase K00029 - 1.1.1.40 0.0 1195.0
HKD3_k127_6327126_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000001766 194.0
HKD3_k127_6327126_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000006116 115.0
HKD3_k127_63788_0 ABC transporter K15738 - - 5.36e-271 876.0
HKD3_k127_63788_1 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.28e-242 779.0
HKD3_k127_63788_2 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 1.527e-206 652.0
HKD3_k127_63788_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 610.0
HKD3_k127_63788_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 466.0
HKD3_k127_63788_5 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 363.0
HKD3_k127_63788_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000007529 108.0
HKD3_k127_63788_7 Domain of unknown function (DUF1992) - - - 0.0000001687 59.0
HKD3_k127_6402403_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0 1024.0
HKD3_k127_6402403_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 530.0
HKD3_k127_6402403_10 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000000000000000000000001531 180.0
HKD3_k127_6402403_11 HDOD domain - - - 0.0000000000000000000000000007058 114.0
HKD3_k127_6402403_12 SNARE associated Golgi protein - - - 0.000000000000000000000000009765 117.0
HKD3_k127_6402403_13 PEP-CTERM motif - - - 0.000000000000000003958 96.0
HKD3_k127_6402403_2 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 463.0
HKD3_k127_6402403_3 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 429.0
HKD3_k127_6402403_4 mechanosensitive ion channel K03442,K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 422.0
HKD3_k127_6402403_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 389.0
HKD3_k127_6402403_6 membrane-bound metal-dependent K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 362.0
HKD3_k127_6402403_7 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 345.0
HKD3_k127_6402403_8 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000004287 275.0
HKD3_k127_6402403_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000004379 227.0
HKD3_k127_6413219_0 extracellular solute-binding protein, family 5 K02035 - - 1.541e-311 963.0
HKD3_k127_6413219_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.401e-309 966.0
HKD3_k127_6413219_10 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 585.0
HKD3_k127_6413219_11 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 578.0
HKD3_k127_6413219_12 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 591.0
HKD3_k127_6413219_13 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 560.0
HKD3_k127_6413219_14 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 529.0
HKD3_k127_6413219_15 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 533.0
HKD3_k127_6413219_16 LysR substrate binding domain K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 510.0
HKD3_k127_6413219_17 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 503.0
HKD3_k127_6413219_18 PFAM binding-protein-dependent transport systems inner membrane component K02034,K13891 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 497.0
HKD3_k127_6413219_19 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 500.0
HKD3_k127_6413219_2 Polysulphide reductase, NrfD K00185 - - 8.285e-236 732.0
HKD3_k127_6413219_20 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 475.0
HKD3_k127_6413219_21 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 438.0
HKD3_k127_6413219_22 Branched-chain amino acid transport system / permease component K01997,K11956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 449.0
HKD3_k127_6413219_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 430.0
HKD3_k127_6413219_24 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 410.0
HKD3_k127_6413219_25 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 396.0
HKD3_k127_6413219_26 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 377.0
HKD3_k127_6413219_27 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 370.0
HKD3_k127_6413219_28 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 355.0
HKD3_k127_6413219_29 Asp/Glu/Hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 350.0
HKD3_k127_6413219_3 Aldo/keto reductase family - - - 3.279e-233 752.0
HKD3_k127_6413219_30 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008196 339.0
HKD3_k127_6413219_31 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006 287.0
HKD3_k127_6413219_32 NADH ubiquinone K05577 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003817 295.0
HKD3_k127_6413219_33 Protein of unknown function (DUF1134) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001403 250.0
HKD3_k127_6413219_34 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004646 261.0
HKD3_k127_6413219_35 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005887 231.0
HKD3_k127_6413219_37 lysozyme - - - 0.000000000000000000000000000000000000000000000000000000000001406 222.0
HKD3_k127_6413219_38 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.000000000000000000000000000000000000000000000000000000000005406 213.0
HKD3_k127_6413219_39 - - - - 0.00000000000000000000000000000000000000000000000000000000002376 208.0
HKD3_k127_6413219_4 Protein of unknown function (DUF3616) - - - 1.004e-219 687.0
HKD3_k127_6413219_40 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000009909 205.0
HKD3_k127_6413219_41 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000006077 214.0
HKD3_k127_6413219_42 Outer Membrane Lipoprotein - GO:0008150,GO:0043900,GO:0050789,GO:0050794,GO:0065007,GO:1900190 - 0.0000000000000000000000000000000000000000000000000000006213 201.0
HKD3_k127_6413219_43 Transcriptional regulator K18939 - - 0.00000000000000000000000000000000000000000000000009656 184.0
HKD3_k127_6413219_44 Transcriptional regulator K19591,K19592 - - 0.000000000000000000000000000000000000000000000004529 181.0
HKD3_k127_6413219_45 Ureidoglycolate lyase K01483 - 4.3.2.3 0.00000000000000000000000000000000000000009616 158.0
HKD3_k127_6413219_48 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000003617 136.0
HKD3_k127_6413219_49 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000000000008562 130.0
HKD3_k127_6413219_5 4Fe-4S dicluster domain K00184 - - 8.831e-211 660.0
HKD3_k127_6413219_50 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase - - - 0.00000000000001449 79.0
HKD3_k127_6413219_51 mercury ion transmembrane transporter activity K07089,K07213 - - 0.00000000000003794 74.0
HKD3_k127_6413219_52 Domain of unknown function (DUF3576) - - - 0.0009062 52.0
HKD3_k127_6413219_6 Receptor family ligand binding region K01999 - - 1.809e-204 662.0
HKD3_k127_6413219_7 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 645.0
HKD3_k127_6413219_8 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 603.0
HKD3_k127_6413219_9 Amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 605.0
HKD3_k127_6485601_0 Penicillin amidase K01434 - 3.5.1.11 2.5e-323 1015.0
HKD3_k127_6485601_1 Amidase K01457 - 3.5.1.54 2.962e-241 762.0
HKD3_k127_6485601_10 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 415.0
HKD3_k127_6485601_11 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 384.0
HKD3_k127_6485601_12 Two component transcriptional regulator K11329 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 355.0
HKD3_k127_6485601_13 Belongs to the WrbA family K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 314.0
HKD3_k127_6485601_14 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 301.0
HKD3_k127_6485601_15 Phenazine biosynthesis-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 306.0
HKD3_k127_6485601_16 Hemolysin III K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 304.0
HKD3_k127_6485601_17 PFAM glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 284.0
HKD3_k127_6485601_18 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008653 278.0
HKD3_k127_6485601_19 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001182 249.0
HKD3_k127_6485601_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02035 - - 8.729e-211 673.0
HKD3_k127_6485601_20 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000001784 231.0
HKD3_k127_6485601_21 ankyrin repeat K06867,K21440 - - 0.00000000000000000000000000000000000000000000000000000000000001017 226.0
HKD3_k127_6485601_22 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000004959 203.0
HKD3_k127_6485601_23 Domain of unknown function (DUF4396) - - - 0.0000000000000000000000000000000000000000000000000001183 195.0
HKD3_k127_6485601_24 UPF0060 membrane protein K09771 - - 0.00000000000000000000000000000000000000000000000003962 183.0
HKD3_k127_6485601_25 Protein of unknown function (DUF3225) - - - 0.000000000000000000000000000000000000000000005955 184.0
HKD3_k127_6485601_26 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000001116 170.0
HKD3_k127_6485601_27 LTXXQ motif family protein - - - 0.00000000000000000000000000000000000000189 168.0
HKD3_k127_6485601_28 Winged helix-turn helix - - - 0.00000000000000000000000000000000000005542 154.0
HKD3_k127_6485601_29 Cmp dcmp deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000004321 144.0
HKD3_k127_6485601_3 ABC transporter substrate-binding protein PnrA-like K02058,K07335 - - 4.941e-202 633.0
HKD3_k127_6485601_30 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000003706 143.0
HKD3_k127_6485601_31 Cold shock protein K03704 - - 0.0000000000000000000000000000000008375 136.0
HKD3_k127_6485601_32 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.0000000000000000000000000000001346 131.0
HKD3_k127_6485601_33 SnoaL-like domain - - - 0.0000000000000000000000000002857 126.0
HKD3_k127_6485601_34 Las17-binding protein actin regulator - - - 0.000000000000000000000000002737 120.0
HKD3_k127_6485601_35 helix_turn_helix, arabinose operon control protein K07506 - - 0.00000000000000000001017 105.0
HKD3_k127_6485601_36 Trypsin-like peptidase domain - - - 0.00000000000000000001515 95.0
HKD3_k127_6485601_37 Protein of unknown function (DUF4089) - - - 0.0000009868 53.0
HKD3_k127_6485601_38 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.00001786 52.0
HKD3_k127_6485601_39 RNA ligase - - - 0.0000209 51.0
HKD3_k127_6485601_4 PFAM Aldehyde oxidase xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 4.126e-194 662.0
HKD3_k127_6485601_40 PFAM 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000293 53.0
HKD3_k127_6485601_5 Amidase K02433,K19837 - 3.5.1.84,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 634.0
HKD3_k127_6485601_6 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 546.0
HKD3_k127_6485601_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 524.0
HKD3_k127_6485601_8 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 474.0
HKD3_k127_6485601_9 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 463.0
HKD3_k127_6599903_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1127.0
HKD3_k127_6599903_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.888e-241 749.0
HKD3_k127_6599903_10 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005001 403.0
HKD3_k127_6599903_11 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 365.0
HKD3_k127_6599903_12 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 362.0
HKD3_k127_6599903_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 334.0
HKD3_k127_6599903_14 PFAM MucB RseB family protein K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 311.0
HKD3_k127_6599903_15 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 291.0
HKD3_k127_6599903_16 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 310.0
HKD3_k127_6599903_17 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001232 270.0
HKD3_k127_6599903_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000008896 207.0
HKD3_k127_6599903_19 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000000000000000000000000434 175.0
HKD3_k127_6599903_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 2.977e-205 651.0
HKD3_k127_6599903_20 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000005115 165.0
HKD3_k127_6599903_21 PFAM Anti sigma-E protein RseA K03597 - - 0.000000000000000000000000000000000000001275 155.0
HKD3_k127_6599903_22 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000007177 144.0
HKD3_k127_6599903_23 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000003057 122.0
HKD3_k127_6599903_25 - - - - 0.000000000155 70.0
HKD3_k127_6599903_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 555.0
HKD3_k127_6599903_4 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 532.0
HKD3_k127_6599903_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 527.0
HKD3_k127_6599903_6 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 523.0
HKD3_k127_6599903_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 480.0
HKD3_k127_6599903_8 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 471.0
HKD3_k127_6599903_9 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 443.0
HKD3_k127_6638917_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 503.0
HKD3_k127_6638917_1 NAD(P) transhydrogenase, alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 384.0
HKD3_k127_6638917_2 carboxylic ester hydrolase activity K06049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 325.0
HKD3_k127_6638917_3 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007001 254.0
HKD3_k127_6695658_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.153e-294 919.0
HKD3_k127_6695658_1 TAP-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 496.0
HKD3_k127_6695658_2 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 458.0
HKD3_k127_6695658_3 ABC-2 family transporter protein K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 458.0
HKD3_k127_6695658_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 379.0
HKD3_k127_6695658_5 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 342.0
HKD3_k127_6695658_6 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 0.000000000000000000000000000000000000000000000000000000000000001948 220.0
HKD3_k127_6695658_7 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000002257 194.0
HKD3_k127_6695658_8 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000003762 185.0
HKD3_k127_6793629_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1064.0
HKD3_k127_6793629_1 Alkyl sulfatase dimerisation K01138 - - 0.0 1062.0
HKD3_k127_6793629_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 421.0
HKD3_k127_6793629_11 Two-component sensor kinase N-terminal K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 360.0
HKD3_k127_6793629_12 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 317.0
HKD3_k127_6793629_13 response regulator K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 306.0
HKD3_k127_6793629_14 Iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001431 248.0
HKD3_k127_6793629_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000004666 236.0
HKD3_k127_6793629_16 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000005249 257.0
HKD3_k127_6793629_17 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000000000000000000000000000000000004731 211.0
HKD3_k127_6793629_18 Domain of unknown function (DUF4377) - - - 0.00000000000000000000000000000000000000000000000008007 192.0
HKD3_k127_6793629_19 DNA-binding transcription factor activity K14057 - - 0.0000000000000000000000000000000000000000000001572 181.0
HKD3_k127_6793629_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.341e-317 987.0
HKD3_k127_6793629_20 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000000000000000000000000000239 179.0
HKD3_k127_6793629_21 lipoprotein NlpE involved in copper resistance - - - 0.0000000000000000000000000008409 126.0
HKD3_k127_6793629_22 MerR HTH family regulatory protein K18997 - - 0.00000000000000000000006312 113.0
HKD3_k127_6793629_23 Phage Terminase - - - 0.00000000000000002791 82.0
HKD3_k127_6793629_24 - - - - 0.000000000002498 75.0
HKD3_k127_6793629_25 - - - - 0.00000000002105 74.0
HKD3_k127_6793629_3 GntP family permease - - - 1.078e-215 678.0
HKD3_k127_6793629_4 Histidine kinase K07638 - 2.7.13.3 3.133e-204 646.0
HKD3_k127_6793629_5 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 500.0
HKD3_k127_6793629_6 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 482.0
HKD3_k127_6793629_7 PFAM response regulator receiver K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 454.0
HKD3_k127_6793629_8 PFAM heat shock protein DnaJ domain protein K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 453.0
HKD3_k127_6793629_9 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 427.0
HKD3_k127_7250090_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1337.0
HKD3_k127_7282643_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1618.0
HKD3_k127_7282643_1 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 4.161e-320 988.0
HKD3_k127_7282643_10 Von Willebrand factor type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 334.0
HKD3_k127_7282643_11 Phosphohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 327.0
HKD3_k127_7282643_12 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 319.0
HKD3_k127_7282643_13 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000864 258.0
HKD3_k127_7282643_14 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000005235 227.0
HKD3_k127_7282643_15 - - - - 0.000000000000000000000000000000000000000000000000000000003096 209.0
HKD3_k127_7282643_16 Copper resistance protein D - - - 0.00000000000000000000000000000000000000000000000001004 190.0
HKD3_k127_7282643_17 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000001733 153.0
HKD3_k127_7282643_18 COG0563 Adenylate kinase and related kinases - - - 0.00000000000000000000000000000000000007014 149.0
HKD3_k127_7282643_19 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000006005 148.0
HKD3_k127_7282643_2 PFAM AMP-dependent synthetase and ligase K18661 - - 1.149e-250 792.0
HKD3_k127_7282643_20 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000000000000006323 130.0
HKD3_k127_7282643_21 Invasion gene expression up-regulator, SirB - - - 0.0000000000000000000000000000006328 127.0
HKD3_k127_7282643_22 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000001577 111.0
HKD3_k127_7282643_23 - - - - 0.000000000000000000000001252 110.0
HKD3_k127_7282643_24 Cytochrome D1 heme domain - - - 0.00000000000000000000001206 110.0
HKD3_k127_7282643_25 YqjK-like protein - - - 0.0000000000000000000000432 104.0
HKD3_k127_7282643_26 Thioredoxin - - - 0.0000000000000000000006467 105.0
HKD3_k127_7282643_27 - - - - 0.000000000000000002056 89.0
HKD3_k127_7282643_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.772e-233 734.0
HKD3_k127_7282643_30 Cysteine-rich CWC - - - 0.00000003878 65.0
HKD3_k127_7282643_4 Nitronate monooxygenase K00459 - 1.13.12.16 2.563e-195 619.0
HKD3_k127_7282643_5 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 523.0
HKD3_k127_7282643_6 Outer membrane receptor for ferrienterochelin and K02014,K16089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 529.0
HKD3_k127_7282643_7 Sulphur transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 511.0
HKD3_k127_7282643_8 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 398.0
HKD3_k127_7282643_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000873 361.0
HKD3_k127_7300781_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 575.0
HKD3_k127_7300781_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007648 279.0
HKD3_k127_7300781_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002665 255.0
HKD3_k127_7300781_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000001183 157.0
HKD3_k127_7327348_0 Enoyl-CoA hydratase/isomerase - - - 0.0 1623.0
HKD3_k127_7327348_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1375.0
HKD3_k127_7327348_10 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 434.0
HKD3_k127_7327348_11 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 434.0
HKD3_k127_7327348_12 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 419.0
HKD3_k127_7327348_13 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 344.0
HKD3_k127_7327348_14 SMART AAA ATPase K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 288.0
HKD3_k127_7327348_15 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000004589 246.0
HKD3_k127_7327348_16 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000269 223.0
HKD3_k127_7327348_17 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000000007376 214.0
HKD3_k127_7327348_18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000001135 167.0
HKD3_k127_7327348_19 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000001289 171.0
HKD3_k127_7327348_2 ABC transporter, transmembrane region K06147 - - 2.054e-298 927.0
HKD3_k127_7327348_20 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000000000000001643 118.0
HKD3_k127_7327348_3 FtsX-like permease family K02004 - - 1.86e-290 915.0
HKD3_k127_7327348_4 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 1.091e-247 771.0
HKD3_k127_7327348_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 4.656e-222 691.0
HKD3_k127_7327348_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 511.0
HKD3_k127_7327348_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 489.0
HKD3_k127_7327348_8 Major Facilitator Superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 485.0
HKD3_k127_7327348_9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 451.0
HKD3_k127_734642_0 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 8.937e-230 722.0
HKD3_k127_734642_1 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 499.0
HKD3_k127_734642_2 Guanine deaminase K01487 - 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 437.0
HKD3_k127_7371999_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 3.202e-305 948.0
HKD3_k127_7371999_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.372e-285 877.0
HKD3_k127_7371999_10 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 304.0
HKD3_k127_7371999_11 PFAM cytochrome P450 K15468 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002356 282.0
HKD3_k127_7371999_12 FAD binding domain K05797 - 1.17.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001316 269.0
HKD3_k127_7371999_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000000000001338 237.0
HKD3_k127_7371999_14 Oxidoreductase FAD-binding domain K00491,K21832 - 1.14.14.47 0.0000000000000000000000000000000000000000000000000000000000002348 239.0
HKD3_k127_7371999_15 TPM domain - - - 0.0000000000000000000000000000000000000000000000000000001111 203.0
HKD3_k127_7371999_16 epimerase - - - 0.00000000000000000000000000000000000000000000000002086 190.0
HKD3_k127_7371999_17 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000002034 156.0
HKD3_k127_7371999_18 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000003245 143.0
HKD3_k127_7371999_19 - - - - 0.000000000000000000000000000000000009444 143.0
HKD3_k127_7371999_2 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 2.041e-270 839.0
HKD3_k127_7371999_20 PFAM Bacterial protein of - - - 0.00000000000000000000000000000000003486 148.0
HKD3_k127_7371999_21 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000003312 140.0
HKD3_k127_7371999_22 cation transporter K03455 - - 0.0000000000006806 83.0
HKD3_k127_7371999_23 GYD domain - - - 0.000000000006545 70.0
HKD3_k127_7371999_24 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0001687 55.0
HKD3_k127_7371999_25 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0009318 47.0
HKD3_k127_7371999_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.528e-200 627.0
HKD3_k127_7371999_4 AAA ATPase domain - - - 3.254e-194 641.0
HKD3_k127_7371999_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 603.0
HKD3_k127_7371999_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 464.0
HKD3_k127_7371999_7 polyphosphate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009267 377.0
HKD3_k127_7371999_8 PFAM LemA family protein K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 322.0
HKD3_k127_7371999_9 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 327.0
HKD3_k127_7379553_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 518.0
HKD3_k127_7379553_1 epimerase K19073 - 1.3.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 496.0
HKD3_k127_7379553_10 Putative regulatory protein - - - 0.0000000000000000001497 99.0
HKD3_k127_7379553_11 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000003529 97.0
HKD3_k127_7379553_2 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 362.0
HKD3_k127_7379553_3 PFAM Ornithine cyclodeaminase mu-crystallin K01750,K19743 - 1.5.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 362.0
HKD3_k127_7379553_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 276.0
HKD3_k127_7379553_5 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003388 274.0
HKD3_k127_7379553_6 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000002513 183.0
HKD3_k127_7379553_8 Belongs to the glycosyl hydrolase 13 family - - - 0.0000000000000000000000000000006629 124.0
HKD3_k127_7379553_9 Glutaredoxin - - - 0.0000000000000000000000000007527 118.0
HKD3_k127_741256_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1605.0
HKD3_k127_741256_1 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 2.382e-314 972.0
HKD3_k127_741256_10 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000000000000005093 170.0
HKD3_k127_741256_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000002112 150.0
HKD3_k127_741256_2 Voltage gated chloride channel - - - 3.264e-216 681.0
HKD3_k127_741256_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009559 533.0
HKD3_k127_741256_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 450.0
HKD3_k127_741256_5 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 441.0
HKD3_k127_741256_6 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003052 276.0
HKD3_k127_741256_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000001025 255.0
HKD3_k127_741256_8 Auxin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005437 231.0
HKD3_k127_741256_9 PFAM Membrane protein of K08972 - - 0.00000000000000000000000000000000000000000002647 166.0
HKD3_k127_7415458_0 pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 2.994e-276 852.0
HKD3_k127_7415458_1 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.855e-274 853.0
HKD3_k127_7415458_10 - - - - 0.0000000000000006406 80.0
HKD3_k127_7415458_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 608.0
HKD3_k127_7415458_3 COG2951 Membrane-bound lytic murein transglycosylase B - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 528.0
HKD3_k127_7415458_4 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 370.0
HKD3_k127_7415458_5 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 346.0
HKD3_k127_7415458_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 323.0
HKD3_k127_7415458_7 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003572 286.0
HKD3_k127_7415458_8 LapD/MoxY periplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000234 269.0
HKD3_k127_7415458_9 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.00000000000000000000000214 104.0
HKD3_k127_7426000_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.327e-240 748.0
HKD3_k127_7426000_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 8.743e-209 658.0
HKD3_k127_7426000_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 578.0
HKD3_k127_7426000_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 429.0
HKD3_k127_7426000_4 Lipid A biosynthesis acyltransferase K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 437.0
HKD3_k127_7426000_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 434.0
HKD3_k127_7426000_6 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 340.0
HKD3_k127_7426000_7 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 325.0
HKD3_k127_7426000_8 helix_turn_helix ASNC type K03719 - - 0.00000000000000000000000000000000000000000000000000005273 191.0
HKD3_k127_7433910_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 5.449e-253 813.0
HKD3_k127_7433910_1 Helicase K03657 - 3.6.4.12 1.837e-196 624.0
HKD3_k127_7433910_10 Sensors of blue-light using FAD - - - 0.00000000000000000001738 97.0
HKD3_k127_7433910_11 Diguanylate cyclase - - - 0.000000000000453 85.0
HKD3_k127_7433910_12 acyl carrier protein - - - 0.0000000015 68.0
HKD3_k127_7433910_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 381.0
HKD3_k127_7433910_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 386.0
HKD3_k127_7433910_4 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000013 271.0
HKD3_k127_7433910_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000572 279.0
HKD3_k127_7433910_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001086 172.0
HKD3_k127_7433910_7 Response regulator receiver - - - 0.00000000000000000000000000000000000000000004911 187.0
HKD3_k127_7433910_8 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000008673 139.0
HKD3_k127_7433910_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000005899 125.0
HKD3_k127_7540431_0 Helicase K03657 - 3.6.4.12 7.025e-309 953.0
HKD3_k127_7540431_1 Bacterial protein of unknown function (DUF839) K07093 - - 1.096e-277 875.0
HKD3_k127_7540431_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 475.0
HKD3_k127_7540431_3 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 465.0
HKD3_k127_7540431_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001273 268.0
HKD3_k127_7540431_5 - - - - 0.00000000000009752 75.0
HKD3_k127_7610668_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 7.945e-261 826.0
HKD3_k127_7610668_1 ABC transporter K02056 - 3.6.3.17 1.659e-252 789.0
HKD3_k127_7610668_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000598 172.0
HKD3_k127_7610668_11 Histone family protein nucleoid-structuring protein H-NS K03746 - - 0.00000000000000000000000000000000834 130.0
HKD3_k127_7610668_2 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 3.807e-252 782.0
HKD3_k127_7610668_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 1.056e-196 620.0
HKD3_k127_7610668_4 basic membrane K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 613.0
HKD3_k127_7610668_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 576.0
HKD3_k127_7610668_6 PFAM extracellular solute-binding protein family 1 K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 527.0
HKD3_k127_7610668_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 479.0
HKD3_k127_7610668_8 Guanine deaminase K01487 - 3.5.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 320.0
HKD3_k127_7610668_9 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000005074 260.0
HKD3_k127_7615301_0 COG0474 Cation transport ATPase - - - 0.0 1321.0
HKD3_k127_7615301_1 Putative diguanylate phosphodiesterase K03320,K13924 - 2.1.1.80,3.1.1.61 0.0 1239.0
HKD3_k127_7615301_10 Belongs to the argininosuccinate synthase family. Type K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 1.209e-253 788.0
HKD3_k127_7615301_11 2-polyprenyl-6-methoxyphenol hydroxylase K05712 - 1.14.13.127 4.849e-253 791.0
HKD3_k127_7615301_12 DNA ligase N terminus K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 7.425e-242 760.0
HKD3_k127_7615301_13 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 1.045e-238 773.0
HKD3_k127_7615301_14 AAA domain - - - 1.163e-223 725.0
HKD3_k127_7615301_15 Outer membrane protein beta-barrel family K02014 - - 1.019e-216 695.0
HKD3_k127_7615301_16 Chromate K07240 - - 1.085e-205 648.0
HKD3_k127_7615301_17 PFAM peptidase S10 serine carboxypeptidase - - - 8.788e-204 648.0
HKD3_k127_7615301_18 Carboxyl transferase domain - - - 2.297e-203 650.0
HKD3_k127_7615301_19 Putative nucleotidyltransferase substrate binding domain K07182 - - 1.481e-197 629.0
HKD3_k127_7615301_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1103.0
HKD3_k127_7615301_20 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 601.0
HKD3_k127_7615301_21 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 587.0
HKD3_k127_7615301_22 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 543.0
HKD3_k127_7615301_23 Luciferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 541.0
HKD3_k127_7615301_24 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 552.0
HKD3_k127_7615301_25 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00162,K21417 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000983 518.0
HKD3_k127_7615301_26 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 482.0
HKD3_k127_7615301_27 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 502.0
HKD3_k127_7615301_28 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K00166,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 458.0
HKD3_k127_7615301_29 ATPases associated with a variety of cellular activities K02010,K02017,K11072 - 3.6.3.29,3.6.3.30,3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 467.0
HKD3_k127_7615301_3 carboxylase K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 3.502e-317 983.0
HKD3_k127_7615301_30 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 454.0
HKD3_k127_7615301_31 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 443.0
HKD3_k127_7615301_32 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007819 440.0
HKD3_k127_7615301_33 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 419.0
HKD3_k127_7615301_34 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 416.0
HKD3_k127_7615301_35 LytTr DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 395.0
HKD3_k127_7615301_36 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 389.0
HKD3_k127_7615301_37 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 388.0
HKD3_k127_7615301_38 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007776 391.0
HKD3_k127_7615301_39 4Fe-4S single cluster domain K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 391.0
HKD3_k127_7615301_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 8.368e-309 961.0
HKD3_k127_7615301_40 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 344.0
HKD3_k127_7615301_41 2OG-Fe dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 361.0
HKD3_k127_7615301_42 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005023 330.0
HKD3_k127_7615301_43 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006116 344.0
HKD3_k127_7615301_44 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
HKD3_k127_7615301_45 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 324.0
HKD3_k127_7615301_46 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 328.0
HKD3_k127_7615301_47 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 303.0
HKD3_k127_7615301_48 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 304.0
HKD3_k127_7615301_49 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 312.0
HKD3_k127_7615301_5 Peptidase family M3 K01284 - 3.4.15.5 8.146e-299 937.0
HKD3_k127_7615301_50 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 310.0
HKD3_k127_7615301_51 import inner membrane translocase subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 300.0
HKD3_k127_7615301_52 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002556 271.0
HKD3_k127_7615301_53 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000002437 271.0
HKD3_k127_7615301_54 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006589 267.0
HKD3_k127_7615301_55 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004061 264.0
HKD3_k127_7615301_56 Dioxygenase K00449 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000000000000001333 260.0
HKD3_k127_7615301_57 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001468 250.0
HKD3_k127_7615301_58 Gram-negative porin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003328 254.0
HKD3_k127_7615301_59 carboxymuconolactone decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007578 246.0
HKD3_k127_7615301_6 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.216e-295 915.0
HKD3_k127_7615301_60 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000000000000000000000000000000004173 254.0
HKD3_k127_7615301_61 YaeQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000009337 252.0
HKD3_k127_7615301_62 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000003741 237.0
HKD3_k127_7615301_63 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000000562 212.0
HKD3_k127_7615301_64 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease - - - 0.0000000000000000000000000000000000000000000000000000000003876 212.0
HKD3_k127_7615301_65 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000005672 222.0
HKD3_k127_7615301_66 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000000000003054 205.0
HKD3_k127_7615301_67 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000001835 203.0
HKD3_k127_7615301_68 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000876 199.0
HKD3_k127_7615301_69 - - - - 0.000000000000000000000000000000000000000000000001398 193.0
HKD3_k127_7615301_7 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 7.366e-294 916.0
HKD3_k127_7615301_70 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000003186 184.0
HKD3_k127_7615301_71 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000634 182.0
HKD3_k127_7615301_72 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000002635 169.0
HKD3_k127_7615301_73 Tyrosine phosphatase family - - - 0.00000000000000000000000000000000000000000002959 168.0
HKD3_k127_7615301_74 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000587 166.0
HKD3_k127_7615301_75 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000008703 156.0
HKD3_k127_7615301_76 CDP-archaeol synthase K19664 - 2.7.7.67 0.0000000000000000000000000000000000000003956 155.0
HKD3_k127_7615301_77 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000000000000409 155.0
HKD3_k127_7615301_78 PFAM regulatory protein, LysR K02019 - - 0.0000000000000000000000000000000000000009105 165.0
HKD3_k127_7615301_8 PFAM AMP-dependent synthetase and ligase K00666 - - 5.648e-284 904.0
HKD3_k127_7615301_80 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000006864 151.0
HKD3_k127_7615301_81 Transglycosylase associated protein - - - 0.000000000000000000000000000001067 130.0
HKD3_k127_7615301_82 Carboxyl transferase domain K01969 - 6.4.1.4 0.000000000000000000000000001896 111.0
HKD3_k127_7615301_83 Cold shock protein K03704 - - 0.00000000000000000000001838 116.0
HKD3_k127_7615301_84 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000004513 104.0
HKD3_k127_7615301_85 - - - - 0.00000000000000000001196 98.0
HKD3_k127_7615301_86 Protein of unknown function (DUF2783) - - - 0.0000000000000000001943 91.0
HKD3_k127_7615301_87 Phosphopantetheine attachment site - - - 0.000000000000000003779 91.0
HKD3_k127_7615301_88 Protein of unknown function (DUF1289) K06938 - - 0.0000000000000001651 91.0
HKD3_k127_7615301_89 Divalent cation transporter K06213 - - 0.00000000000003423 73.0
HKD3_k127_7615301_9 AMP-binding enzyme C-terminal domain K00666 - - 3.399e-260 816.0
HKD3_k127_7615301_90 - - - - 0.000000000000162 75.0
HKD3_k127_7615301_94 transporter K14445 - - 0.0000644 49.0
HKD3_k127_7662502_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.606e-250 780.0
HKD3_k127_7662502_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 5.261e-241 758.0
HKD3_k127_7662502_2 Fasciclin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002342 314.0
HKD3_k127_7662502_3 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000379 220.0
HKD3_k127_7662502_4 Beta-Ig-H3 fasciclin - - - 0.00000000000000000000000000000000000000000000000000000000002608 211.0
HKD3_k127_7662502_5 hydrogenase maturation protease - - - 0.0000000000000000000000000000000000000000003837 174.0
HKD3_k127_7764394_0 aconitate hydratase K01681 - 4.2.1.3 2.56e-247 769.0
HKD3_k127_7764394_1 Cytochrome P450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 477.0
HKD3_k127_7764394_10 Belongs to the ArsC family K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000004935 175.0
HKD3_k127_7764394_11 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000002782 161.0
HKD3_k127_7764394_12 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000001846 152.0
HKD3_k127_7764394_13 - - - - 0.00000000000000000000000285 105.0
HKD3_k127_7764394_14 Putative mono-oxygenase ydhR - - - 0.000000000000000000000005328 120.0
HKD3_k127_7764394_2 DNA alkylation repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 467.0
HKD3_k127_7764394_3 Steryl acetyl hydrolase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 455.0
HKD3_k127_7764394_4 Protein tyrosine serine phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 301.0
HKD3_k127_7764394_5 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000937 286.0
HKD3_k127_7764394_6 transcriptional regulator - GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009987,GO:0010212,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001293 278.0
HKD3_k127_7764394_7 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003724 253.0
HKD3_k127_7764394_8 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000001041 256.0
HKD3_k127_7764394_9 Cysteine-rich secretory protein family - - - 0.000000000000000000000000000000000000000000003717 171.0
HKD3_k127_780719_0 fad dependent oxidoreductase K07137 - - 1.242e-285 889.0
HKD3_k127_780719_1 Sulfate transporter antisigma-factor antagonist STAS - - - 2.1e-272 848.0
HKD3_k127_780719_10 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000000000009868 210.0
HKD3_k127_780719_11 - - - - 0.00000000000003623 74.0
HKD3_k127_780719_12 Putative transposase - - - 0.0000000001355 75.0
HKD3_k127_780719_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 6.597e-216 685.0
HKD3_k127_780719_3 Amidase K01426 - 3.5.1.4 1.467e-195 642.0
HKD3_k127_780719_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 561.0
HKD3_k127_780719_5 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 490.0
HKD3_k127_780719_6 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 GO:0000166,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0003999,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0012505,GO:0016192,GO:0016208,GO:0016740,GO:0016757,GO:0016763,GO:0017076,GO:0018130,GO:0019438,GO:0030141,GO:0030554,GO:0031410,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0034641,GO:0034654,GO:0034774,GO:0036094,GO:0036230,GO:0042119,GO:0043094,GO:0043101,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046483,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0072521,GO:0072522,GO:0097159,GO:0097367,GO:0097708,GO:0099503,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 317.0
HKD3_k127_780719_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000004674 269.0
HKD3_k127_780719_8 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000000000000000000000000000002506 208.0
HKD3_k127_780719_9 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000005258 213.0
HKD3_k127_7848087_0 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.056e-286 885.0
HKD3_k127_7848087_1 Major Facilitator - - - 1.972e-219 687.0
HKD3_k127_7848087_10 Uncharacterised protein family (UPF0149) K07039 - - 0.000000000000000000000000000000000000000000000000000000000000000001098 234.0
HKD3_k127_7848087_11 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000000000000000000000000000000002136 243.0
HKD3_k127_7848087_12 SMART helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000000000000000000000000000000000001108 222.0
HKD3_k127_7848087_13 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000001899 198.0
HKD3_k127_7848087_14 RF-1 domain K15034 - - 0.000000000000000000000000000000000000000000002082 168.0
HKD3_k127_7848087_15 Redoxin - - - 0.000000000000000000000000000000000000001174 168.0
HKD3_k127_7848087_16 acetyltransferase - - - 0.0000000000000000000000000000000002462 144.0
HKD3_k127_7848087_17 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000616 134.0
HKD3_k127_7848087_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 585.0
HKD3_k127_7848087_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 475.0
HKD3_k127_7848087_4 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008279 455.0
HKD3_k127_7848087_5 Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 449.0
HKD3_k127_7848087_6 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 401.0
HKD3_k127_7848087_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 356.0
HKD3_k127_7848087_8 EamA-like transporter family K03298 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001675 255.0
HKD3_k127_7848087_9 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000005038 230.0
HKD3_k127_7855312_0 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K04090 - 1.2.7.8 4.294e-201 632.0
HKD3_k127_7855312_1 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 287.0
HKD3_k127_7855312_2 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005043 270.0
HKD3_k127_7855312_3 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009673 278.0
HKD3_k127_7855312_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 250.0
HKD3_k127_7855312_5 YceI-like domain - - - 0.00000000000000000000000000000000000000000000000000000001778 203.0
HKD3_k127_7855312_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000009459 137.0
HKD3_k127_7855312_8 Lysozyme inhibitor LprI - - - 0.0000000003046 74.0
HKD3_k127_8002488_0 Na H antiporter MnhB subunit-related protein - - - 0.0 1338.0
HKD3_k127_8002488_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.509e-295 910.0
HKD3_k127_8002488_10 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 464.0
HKD3_k127_8002488_11 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 442.0
HKD3_k127_8002488_12 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 417.0
HKD3_k127_8002488_13 Transcriptional regulatory protein, C terminal K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 347.0
HKD3_k127_8002488_14 Alpha beta hydrolase K06049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 310.0
HKD3_k127_8002488_15 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001216 274.0
HKD3_k127_8002488_16 PFAM 2-vinyl bacteriochlorophyllide hydratase K11336 - 4.2.1.165 0.0000000000000000000000000000000000000000000000000000000000000009777 224.0
HKD3_k127_8002488_17 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000006605 214.0
HKD3_k127_8002488_18 Na+/H+ antiporter subunit K05564 - - 0.0000000000000000000000000000000000000000000000000001371 187.0
HKD3_k127_8002488_19 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000006729 194.0
HKD3_k127_8002488_2 Domain of unknown function (DUF3390) K18929 - - 1.61e-245 781.0
HKD3_k127_8002488_20 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000000000581 188.0
HKD3_k127_8002488_21 NADH-ubiquinone oxidoreductase chain 4L K05560 - - 0.0000000000000000000000000000000000000000009796 181.0
HKD3_k127_8002488_22 Multiple resistance and pH regulation protein F K05563 - - 0.00000000000000000000000001647 120.0
HKD3_k127_8002488_23 Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (BchN-BchB) is the catalytic component of the complex K04038 - 1.3.7.7 0.0000000000000000001957 97.0
HKD3_k127_8002488_24 - - - - 0.000000000001581 73.0
HKD3_k127_8002488_25 - - - - 0.00000000004386 70.0
HKD3_k127_8002488_3 NADH Ubiquinone plastoquinone (Complex I) K05561 - - 6.152e-241 762.0
HKD3_k127_8002488_4 Putative citrate transport - - - 7.847e-228 713.0
HKD3_k127_8002488_5 FAD binding domain K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 580.0
HKD3_k127_8002488_6 von Willebrand factor (vWF) type A domain K03404 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 585.0
HKD3_k127_8002488_7 Magnesium chelatase, subunit ChlI K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 535.0
HKD3_k127_8002488_8 PUCC protein K08226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 530.0
HKD3_k127_8002488_9 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 500.0
HKD3_k127_8012369_0 Histidine kinase - - - 8.348e-291 925.0
HKD3_k127_8012369_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 565.0
HKD3_k127_8012369_2 GTP cyclohydrolase K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 415.0
HKD3_k127_8012369_3 Response regulator receiver K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 381.0
HKD3_k127_8012369_4 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000000000000006351 205.0
HKD3_k127_8012369_5 Sensors of blue-light using FAD - - - 0.00000000000000000000000000000000000000000000000000001873 203.0
HKD3_k127_8012369_6 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.00000000000000000000000000000000000000002403 152.0
HKD3_k127_8115616_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1138.0
HKD3_k127_8115616_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 5.786e-313 968.0
HKD3_k127_8115616_10 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 421.0
HKD3_k127_8115616_11 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 404.0
HKD3_k127_8115616_12 PFAM Integral membrane protein TerC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 390.0
HKD3_k127_8115616_13 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 369.0
HKD3_k127_8115616_14 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 347.0
HKD3_k127_8115616_15 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 334.0
HKD3_k127_8115616_16 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005001 244.0
HKD3_k127_8115616_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000001291 220.0
HKD3_k127_8115616_18 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
HKD3_k127_8115616_19 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001426 216.0
HKD3_k127_8115616_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 8.361e-285 889.0
HKD3_k127_8115616_20 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000001406 207.0
HKD3_k127_8115616_21 - - - - 0.000000000000000000000000000000000000000000000000000000002586 202.0
HKD3_k127_8115616_22 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000000000000000000001146 196.0
HKD3_k127_8115616_23 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000000000000000000114 184.0
HKD3_k127_8115616_24 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000000000000001231 143.0
HKD3_k127_8115616_25 - - - - 0.000000000000000002091 93.0
HKD3_k127_8115616_3 Patatin-like phospholipase - - - 3.292e-221 705.0
HKD3_k127_8115616_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 4.223e-221 709.0
HKD3_k127_8115616_5 Serine threonine protein kinase K12132 - 2.7.11.1 2.575e-199 630.0
HKD3_k127_8115616_6 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 586.0
HKD3_k127_8115616_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 544.0
HKD3_k127_8115616_8 Tryptophan halogenase K21401 - 1.3.99.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 549.0
HKD3_k127_8115616_9 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 465.0
HKD3_k127_8467458_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 586.0
HKD3_k127_8467458_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 484.0
HKD3_k127_8467458_10 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009015 326.0
HKD3_k127_8467458_11 PFAM Asparaginase glutaminase K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 328.0
HKD3_k127_8467458_12 Chromate transporter K07240 - - 0.000000000000000000000000000000000000000000000000000000001274 209.0
HKD3_k127_8467458_13 Chromate transporter K07240 - - 0.0000000000000000000000000000000000000000000000000002178 199.0
HKD3_k127_8467458_14 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000003599 183.0
HKD3_k127_8467458_15 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000001935 189.0
HKD3_k127_8467458_16 Pathogenicity locus K07343 - - 0.0000000000000000000000000000000000001229 143.0
HKD3_k127_8467458_17 - - - - 0.00000000000000000000663 98.0
HKD3_k127_8467458_18 - - - - 0.00000000000000000007727 91.0
HKD3_k127_8467458_2 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 433.0
HKD3_k127_8467458_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 411.0
HKD3_k127_8467458_4 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 381.0
HKD3_k127_8467458_5 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 376.0
HKD3_k127_8467458_6 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 401.0
HKD3_k127_8467458_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 372.0
HKD3_k127_8467458_8 PFAM Transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 398.0
HKD3_k127_8467458_9 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 376.0
HKD3_k127_8481064_0 Histidine kinase - - - 6.978e-319 1050.0
HKD3_k127_8481064_1 ABC transporter K06158 - - 8.71e-308 959.0
HKD3_k127_8481064_10 Belongs to the protein N5-glutamine methyltransferase family K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 438.0
HKD3_k127_8481064_11 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 364.0
HKD3_k127_8481064_12 Transcriptional regulatory protein, C terminal K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 328.0
HKD3_k127_8481064_13 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 310.0
HKD3_k127_8481064_14 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000006092 237.0
HKD3_k127_8481064_15 Thermostable hemolysin - - - 0.00000000000000000000000000000000000000000000000000000000002217 213.0
HKD3_k127_8481064_16 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000315 179.0
HKD3_k127_8481064_17 Winged helix-turn helix - - - 0.0005274 50.0
HKD3_k127_8481064_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006,K01007 - 2.7.9.1,2.7.9.2 4.036e-238 741.0
HKD3_k127_8481064_3 Long-chain acyl-CoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 610.0
HKD3_k127_8481064_4 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 597.0
HKD3_k127_8481064_5 chemotaxis sensory transducer K03406,K03776,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 519.0
HKD3_k127_8481064_6 twitching motility protein K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 491.0
HKD3_k127_8481064_7 Histidine kinase K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007673 484.0
HKD3_k127_8481064_8 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 459.0
HKD3_k127_8481064_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 437.0
HKD3_k127_8527179_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 4.388e-291 919.0
HKD3_k127_8527179_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 444.0
HKD3_k127_8527179_2 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009342 411.0
HKD3_k127_8527179_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 408.0
HKD3_k127_8527179_4 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 403.0
HKD3_k127_8527179_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 389.0
HKD3_k127_8527179_6 Tripartite ATP-independent periplasmic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 358.0
HKD3_k127_8527179_7 benzoate-CoA ligase K04110 - 6.2.1.25 0.00000000000000000000000000000000000000000000000000000000000000000005288 232.0
HKD3_k127_8535501_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 567.0
HKD3_k127_8535501_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 529.0
HKD3_k127_8535501_10 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000000000001057 235.0
HKD3_k127_8535501_11 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000006108 167.0
HKD3_k127_8535501_12 - - - - 0.0001619 53.0
HKD3_k127_8535501_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 498.0
HKD3_k127_8535501_3 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 477.0
HKD3_k127_8535501_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 382.0
HKD3_k127_8535501_5 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 361.0
HKD3_k127_8535501_6 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009902 351.0
HKD3_k127_8535501_7 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 332.0
HKD3_k127_8535501_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000006228 275.0
HKD3_k127_8535501_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000001427 254.0
HKD3_k127_8535636_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1025.0
HKD3_k127_8535636_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 1.512e-273 850.0
HKD3_k127_8535636_10 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 364.0
HKD3_k127_8535636_11 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 368.0
HKD3_k127_8535636_12 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 352.0
HKD3_k127_8535636_13 Spermine/spermidine synthase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 366.0
HKD3_k127_8535636_14 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 304.0
HKD3_k127_8535636_15 Type II secretion system (T2SS), protein N K02463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 299.0
HKD3_k127_8535636_16 Gram-negative porin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001426 273.0
HKD3_k127_8535636_17 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000000000000001961 241.0
HKD3_k127_8535636_18 Prokaryotic N-terminal methylation motif K02459 - - 0.0000000000000000000000000000000000000000000000000000000000000000134 235.0
HKD3_k127_8535636_19 general secretion pathway protein K02456 - - 0.0000000000000000000000000000000000000000000000000000000000001013 244.0
HKD3_k127_8535636_2 general secretion pathway protein K02453 - - 6.106e-263 846.0
HKD3_k127_8535636_20 Spermidine synthase - - - 0.0000000000000000000000000000000000000000000000000000004509 202.0
HKD3_k127_8535636_21 general secretion pathway protein K02458 - - 0.000000000000000000000000000000000000000000000683 178.0
HKD3_k127_8535636_22 PFAM General secretion pathway, M protein K02462 - - 0.0000000000000000000000000000000000000002576 160.0
HKD3_k127_8535636_23 general secretion pathway protein H K02457 - - 0.00000000000000000000000000000000002044 146.0
HKD3_k127_8535636_24 general secretion pathway protein K02452 - - 0.0000000000000000000000003476 116.0
HKD3_k127_8535636_25 - - - - 0.000000000000000000001561 99.0
HKD3_k127_8535636_3 TIGRFAM general secretory pathway protein E K02454,K02652 - - 2.28e-254 789.0
HKD3_k127_8535636_4 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.785e-252 794.0
HKD3_k127_8535636_5 General secretion pathway protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 589.0
HKD3_k127_8535636_6 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 563.0
HKD3_k127_8535636_7 PFAM 5-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 467.0
HKD3_k127_8535636_8 General secretion pathway K02461 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 435.0
HKD3_k127_8535636_9 Phosphoribosyltransferase K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 381.0
HKD3_k127_8556465_0 Peptidase dimerisation domain - - - 1.038e-254 807.0
HKD3_k127_8556465_1 GMC family oxidoreductase - - - 4.101e-251 784.0
HKD3_k127_8556465_2 Phosphotransferase K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 504.0
HKD3_k127_8556465_3 enoyl-CoA hydratase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 408.0
HKD3_k127_8556465_4 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 331.0
HKD3_k127_8556465_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000143 288.0
HKD3_k127_8556465_6 - - - - 0.0000000000000000000000000000000000000000000000001096 184.0
HKD3_k127_8556465_7 - - - - 0.00000000000000000000000000357 121.0
HKD3_k127_8574912_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 0.0 1039.0
HKD3_k127_8574912_1 Bacterial protein of unknown function (DUF839) K07093 - - 7.121e-297 975.0
HKD3_k127_8574912_10 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 463.0
HKD3_k127_8574912_11 Transcriptional regulator K05596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 449.0
HKD3_k127_8574912_12 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 414.0
HKD3_k127_8574912_13 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 370.0
HKD3_k127_8574912_14 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 366.0
HKD3_k127_8574912_15 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 366.0
HKD3_k127_8574912_16 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 334.0
HKD3_k127_8574912_17 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 341.0
HKD3_k127_8574912_18 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 316.0
HKD3_k127_8574912_19 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003973 282.0
HKD3_k127_8574912_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.215e-272 850.0
HKD3_k127_8574912_20 PFAM regulatory protein TetR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002178 264.0
HKD3_k127_8574912_21 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005837 259.0
HKD3_k127_8574912_22 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000002562 265.0
HKD3_k127_8574912_23 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002485 237.0
HKD3_k127_8574912_24 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000003547 231.0
HKD3_k127_8574912_25 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000002406 209.0
HKD3_k127_8574912_26 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000009345 160.0
HKD3_k127_8574912_27 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000005961 140.0
HKD3_k127_8574912_28 - - - - 0.0000893 47.0
HKD3_k127_8574912_3 D-amino acid K00285 - 1.4.5.1 5.369e-230 718.0
HKD3_k127_8574912_4 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 1.193e-229 719.0
HKD3_k127_8574912_5 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 3.966e-222 693.0
HKD3_k127_8574912_6 Aminotransferase class I and II K00832 - 2.6.1.57 1.547e-198 645.0
HKD3_k127_8574912_7 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 607.0
HKD3_k127_8574912_8 NADH flavin oxidoreductase NADH oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 541.0
HKD3_k127_8574912_9 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007966 542.0
HKD3_k127_8582096_0 KR domain - - - 0.0 1506.0
HKD3_k127_8582096_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K14471 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008410,GO:0015977,GO:0016740,GO:0016782,GO:0043427,GO:0071704 2.8.3.22 1.441e-195 616.0
HKD3_k127_8582096_2 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 540.0
HKD3_k127_8582096_3 N-terminal half of MaoC dehydratase K09709 - 4.2.1.153 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 374.0
HKD3_k127_8584516_0 Alanine racemase K19967 - 4.1.2.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 486.0
HKD3_k127_8584516_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 330.0
HKD3_k127_8584516_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001333 264.0
HKD3_k127_8584516_3 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000000000000000000000000000004979 214.0
HKD3_k127_8584516_4 Major Facilitator Superfamily - - - 0.0000000000000000000007635 109.0
HKD3_k127_8584516_5 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.00000000000000009703 86.0
HKD3_k127_86068_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 3.668e-228 711.0
HKD3_k127_86068_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 1.205e-200 629.0
HKD3_k127_86068_10 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000000000000000000000000002053 132.0
HKD3_k127_86068_11 - - - - 0.00000000000000000000000001383 128.0
HKD3_k127_86068_12 FabA-like domain - - - 0.0000000000000000000002327 108.0
HKD3_k127_86068_13 - - - - 0.0000000000000000482 89.0
HKD3_k127_86068_14 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.0000000000000001651 95.0
HKD3_k127_86068_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 625.0
HKD3_k127_86068_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 475.0
HKD3_k127_86068_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 398.0
HKD3_k127_86068_5 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 329.0
HKD3_k127_86068_6 KR domain K10780 - 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 316.0
HKD3_k127_86068_7 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000001067 228.0
HKD3_k127_86068_8 lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000001947 233.0
HKD3_k127_86068_9 Phosphopantetheine attachment site - - - 0.0000000000000000000000000000000000001873 145.0
HKD3_k127_8608553_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1159.0
HKD3_k127_8608553_1 Sulfate transporter K03321 - - 3.95e-245 770.0
HKD3_k127_8608553_10 Rhodanese-like domain - - - 0.0000009448 51.0
HKD3_k127_8608553_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 566.0
HKD3_k127_8608553_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 502.0
HKD3_k127_8608553_4 CYTH K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 449.0
HKD3_k127_8608553_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 445.0
HKD3_k127_8608553_6 (Lipo)protein - - - 0.00000000000000000000000000000000000000000000000000003274 196.0
HKD3_k127_8608553_7 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000001158 170.0
HKD3_k127_8608553_8 response regulator - - - 0.0000000000000000000000000000000000000000000007411 177.0
HKD3_k127_8608553_9 Protein of unknown function (DUF3460) - - - 0.0000000000000000000000000013 113.0
HKD3_k127_86520_0 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1894.0
HKD3_k127_86520_1 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 524.0
HKD3_k127_86520_2 Regulator K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 336.0
HKD3_k127_86520_3 transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 0.0000000001397 64.0
HKD3_k127_8673575_0 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 520.0
HKD3_k127_8673575_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 427.0
HKD3_k127_8673575_10 Serine aminopeptidase, S33 K01055 - 3.1.1.24 0.0000000002358 74.0
HKD3_k127_8673575_2 Esterase PHB depolymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 361.0
HKD3_k127_8673575_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 350.0
HKD3_k127_8673575_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 327.0
HKD3_k127_8673575_5 Protein of unknown function (DUF938) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001321 255.0
HKD3_k127_8673575_6 - - - - 0.00000000000000000000000000000000000000000000000000000026 203.0
HKD3_k127_8673575_7 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000006602 186.0
HKD3_k127_8673575_8 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000000001501 142.0
HKD3_k127_8673575_9 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000004419 106.0
HKD3_k127_8685679_0 MaoC like domain K02618 - 1.2.1.91,3.3.2.12 0.0 1142.0
HKD3_k127_8685679_1 ABC-type Fe3 transport system, permease component K02011 - - 7.989e-241 755.0
HKD3_k127_8685679_10 PFAM phenylacetic acid catabolic family protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 378.0
HKD3_k127_8685679_11 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002789 274.0
HKD3_k127_8685679_12 TIGRFAM phenylacetate-CoA oxygenase, PaaJ subunit K02612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005599 259.0
HKD3_k127_8685679_13 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000000000000002985 165.0
HKD3_k127_8685679_14 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000000000000000006354 151.0
HKD3_k127_8685679_15 TIGRFAM phenylacetate-CoA oxygenase, PaaH subunit K02610 - - 0.00000000000000000000000000000003003 125.0
HKD3_k127_8685679_16 PFAM Excalibur calcium-binding domain - - - 0.0000000000000000002316 101.0
HKD3_k127_8685679_17 - - - - 0.0000000000004567 78.0
HKD3_k127_8685679_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 8.721e-234 777.0
HKD3_k127_8685679_3 oxidoreductase FAD NAD(P)-binding domain protein K02613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 614.0
HKD3_k127_8685679_4 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 559.0
HKD3_k127_8685679_5 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 516.0
HKD3_k127_8685679_6 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 463.0
HKD3_k127_8685679_7 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 448.0
HKD3_k127_8685679_8 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 399.0
HKD3_k127_8685679_9 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 385.0
HKD3_k127_8687387_0 Male sterility protein - - - 0.0 1114.0
HKD3_k127_8687387_1 Involved in the biosynthesis of porphyrin-containing compound - - - 1.115e-196 622.0
HKD3_k127_8687387_10 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 330.0
HKD3_k127_8687387_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 295.0
HKD3_k127_8687387_12 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 310.0
HKD3_k127_8687387_13 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 288.0
HKD3_k127_8687387_14 phosphoglycolate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000106 265.0
HKD3_k127_8687387_15 PFAM globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000002117 220.0
HKD3_k127_8687387_16 metal-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000006407 212.0
HKD3_k127_8687387_17 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000000000000000000000000000000000000000005586 203.0
HKD3_k127_8687387_18 - - - - 0.0000000000000000000000000000000000000000000000000002797 199.0
HKD3_k127_8687387_19 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000000000000000000000000004347 171.0
HKD3_k127_8687387_2 Serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 613.0
HKD3_k127_8687387_20 PFAM multicopper oxidase type K22348 - 1.16.3.3 0.00000000000000000000000000000000000000003851 154.0
HKD3_k127_8687387_21 - - - - 0.0000000000000000000000000000000000000006594 158.0
HKD3_k127_8687387_22 Copper binding periplasmic protein CusF - - - 0.000000000000000000000000002567 123.0
HKD3_k127_8687387_23 Heavy-metal-associated domain K08364 - - 0.000000000000000000000000003458 115.0
HKD3_k127_8687387_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 586.0
HKD3_k127_8687387_4 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 525.0
HKD3_k127_8687387_5 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 480.0
HKD3_k127_8687387_6 phosphatase K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 443.0
HKD3_k127_8687387_7 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 404.0
HKD3_k127_8687387_8 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 400.0
HKD3_k127_8687387_9 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 406.0
HKD3_k127_8718557_0 Histidine kinase K03407 GO:0003674,GO:0005488,GO:0005515,GO:0019904 2.7.13.3 0.0 1067.0
HKD3_k127_8718557_1 Flagellar motor switch K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 565.0
HKD3_k127_8718557_10 - - - - 0.00000000000000000000000000000000000000000004012 165.0
HKD3_k127_8718557_11 Role in flagellar biosynthesis K02420 - - 0.000000000000000000000000000000000002957 140.0
HKD3_k127_8718557_12 Flagellar biosynthesis protein, FliO K02418 - - 0.000000000000000000000005506 111.0
HKD3_k127_8718557_13 Flagellar hook-length control protein K02414 - - 0.00000000000000000002028 106.0
HKD3_k127_8718557_2 Methyl-accepting chemotaxis protein K03406,K03776,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 466.0
HKD3_k127_8718557_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 462.0
HKD3_k127_8718557_4 luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 370.0
HKD3_k127_8718557_5 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 370.0
HKD3_k127_8718557_6 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 359.0
HKD3_k127_8718557_7 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000005277 233.0
HKD3_k127_8718557_8 Flagellar motor switch protein fliN K02417,K03225 - - 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
HKD3_k127_8718557_9 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000000000002619 194.0
HKD3_k127_8739362_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 2.907e-279 866.0
HKD3_k127_8739362_1 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 544.0
HKD3_k127_8739362_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 490.0
HKD3_k127_8739362_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 389.0
HKD3_k127_8739362_4 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 348.0
HKD3_k127_8739362_5 FAD binding domain K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004737 286.0
HKD3_k127_8739362_6 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000172 222.0
HKD3_k127_8739362_7 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000000000006471 132.0
HKD3_k127_8739362_8 - - - - 0.00000000000000000000000001966 118.0
HKD3_k127_8749177_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1146.0
HKD3_k127_8749177_1 NADPH-dependent glutamate synthase beta - - - 4.876e-310 972.0
HKD3_k127_8749177_10 Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 577.0
HKD3_k127_8749177_11 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 552.0
HKD3_k127_8749177_12 Peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 562.0
HKD3_k127_8749177_13 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007682 530.0
HKD3_k127_8749177_14 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 542.0
HKD3_k127_8749177_15 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 518.0
HKD3_k127_8749177_16 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 529.0
HKD3_k127_8749177_17 associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 497.0
HKD3_k127_8749177_18 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 472.0
HKD3_k127_8749177_19 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 484.0
HKD3_k127_8749177_2 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.706e-300 925.0
HKD3_k127_8749177_20 Carboxylesterase family K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 453.0
HKD3_k127_8749177_21 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 459.0
HKD3_k127_8749177_22 PFAM MscS Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 476.0
HKD3_k127_8749177_23 phosphotransferase related to Ser Thr protein kinases K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 440.0
HKD3_k127_8749177_24 PFAM molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 423.0
HKD3_k127_8749177_25 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 425.0
HKD3_k127_8749177_26 Lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 417.0
HKD3_k127_8749177_27 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 392.0
HKD3_k127_8749177_28 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 424.0
HKD3_k127_8749177_29 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 376.0
HKD3_k127_8749177_3 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 1.111e-253 809.0
HKD3_k127_8749177_30 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 368.0
HKD3_k127_8749177_31 Polycystin cation channel K08714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 370.0
HKD3_k127_8749177_32 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 362.0
HKD3_k127_8749177_33 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 352.0
HKD3_k127_8749177_34 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 332.0
HKD3_k127_8749177_35 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 337.0
HKD3_k127_8749177_36 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 326.0
HKD3_k127_8749177_37 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 306.0
HKD3_k127_8749177_38 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 314.0
HKD3_k127_8749177_39 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007694 299.0
HKD3_k127_8749177_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.118e-238 747.0
HKD3_k127_8749177_40 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 286.0
HKD3_k127_8749177_41 Nudix hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001728 279.0
HKD3_k127_8749177_42 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005477 267.0
HKD3_k127_8749177_43 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008553 263.0
HKD3_k127_8749177_44 Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000009592 267.0
HKD3_k127_8749177_45 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000000000006111 252.0
HKD3_k127_8749177_46 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000001735 237.0
HKD3_k127_8749177_47 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000003122 239.0
HKD3_k127_8749177_48 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000000000000000000000000000000000312 231.0
HKD3_k127_8749177_49 Belongs to the DnaA family K10763 - - 0.00000000000000000000000000000000000000000000000000000000000001616 246.0
HKD3_k127_8749177_5 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 2.139e-216 695.0
HKD3_k127_8749177_50 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000000000816 217.0
HKD3_k127_8749177_51 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000026 198.0
HKD3_k127_8749177_52 - - - - 0.0000000000000000000000000000000000000000000000000000149 197.0
HKD3_k127_8749177_53 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000000000002417 203.0
HKD3_k127_8749177_54 TM2 domain - - - 0.0000000000000000000000000000000000000000000000000003527 198.0
HKD3_k127_8749177_55 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000001212 179.0
HKD3_k127_8749177_56 ferredoxin - - - 0.0000000000000000000000000000000000000000000232 168.0
HKD3_k127_8749177_57 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000000000008811 162.0
HKD3_k127_8749177_58 - - - - 0.0000000000000000000000000000000000000000001426 181.0
HKD3_k127_8749177_59 Protein of unknown function (DUF3579) - - - 0.0000000000000000000000000000000000000000006736 177.0
HKD3_k127_8749177_6 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 4.881e-215 673.0
HKD3_k127_8749177_60 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000001007 159.0
HKD3_k127_8749177_61 PFAM OmpA MotB domain protein - - - 0.00000000000000000000000000000000000000001916 160.0
HKD3_k127_8749177_62 PFAM small multidrug resistance protein K11741 - - 0.000000000000000000000000000000000000169 153.0
HKD3_k127_8749177_63 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000003264 141.0
HKD3_k127_8749177_64 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000002149 133.0
HKD3_k127_8749177_65 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000003496 122.0
HKD3_k127_8749177_66 Cytochrome c - - - 0.000000000000000000000000009869 113.0
HKD3_k127_8749177_67 - - - - 0.000000000000004185 79.0
HKD3_k127_8749177_68 Protein of unknown function (DUF3460) - - - 0.00000000000001971 76.0
HKD3_k127_8749177_69 - - - - 0.0000001233 65.0
HKD3_k127_8749177_7 TIGRFAM nitrogen regulation protein NR(I) K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 9.324e-213 671.0
HKD3_k127_8749177_70 - - - - 0.0002764 51.0
HKD3_k127_8749177_8 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 608.0
HKD3_k127_8749177_9 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 599.0
HKD3_k127_8839086_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 8.517e-294 923.0
HKD3_k127_8839086_1 Participates in both transcription termination and antitermination K02600 - - 4.802e-276 865.0
HKD3_k127_8839086_10 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 442.0
HKD3_k127_8839086_11 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 449.0
HKD3_k127_8839086_12 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01200 - 3.2.1.1,3.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005547 413.0
HKD3_k127_8839086_13 Bacterial pullanase-associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002004 279.0
HKD3_k127_8839086_14 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000000000000000000000006357 228.0
HKD3_k127_8839086_15 - - - - 0.000000000000000000000000000000000000000000000000000000000001927 236.0
HKD3_k127_8839086_2 Alpha amylase, catalytic domain K01176 - 3.2.1.1 5.902e-273 891.0
HKD3_k127_8839086_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033554,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0071704,GO:1901576 2.4.1.18 4.036e-260 822.0
HKD3_k127_8839086_4 Maltose transport system permease protein MalF P2 domain K10109 - - 6.487e-241 755.0
HKD3_k127_8839086_5 Bacterial extracellular solute-binding protein K10108 - - 6.245e-233 729.0
HKD3_k127_8839086_6 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 642.0
HKD3_k127_8839086_7 ABC transporter K10111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 566.0
HKD3_k127_8839086_8 Binding-protein-dependent transport system inner membrane component K10110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 519.0
HKD3_k127_8839086_9 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 554.0
HKD3_k127_8866794_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.597e-244 762.0
HKD3_k127_8866794_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 379.0
HKD3_k127_8866794_2 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 352.0
HKD3_k127_8866794_3 Bacteriochlorophyll 4-vinyl reductase K04036 GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0033013,GO:0033014,GO:0034641,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001098 256.0
HKD3_k127_8866794_4 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000000000000000000000000000001756 232.0
HKD3_k127_8866794_5 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000002218 189.0
HKD3_k127_8866794_6 B12 binding domain K04034 - 1.21.98.3 0.00000000000000000000000000000000000000002076 155.0
HKD3_k127_8866794_7 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000002779 151.0
HKD3_k127_8866794_8 AAA domain - - - 0.00000000000000000000000005633 124.0
HKD3_k127_8866794_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000005865 114.0
HKD3_k127_8901261_0 PFAM ATP-binding region, ATPase domain protein - - - 0.0 1140.0
HKD3_k127_8901261_1 Regulator K13041 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 372.0
HKD3_k127_8901261_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 308.0
HKD3_k127_8901261_3 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.00000000000476 72.0
HKD3_k127_8909680_0 histidine kinase A domain protein - - - 0.0 1304.0
HKD3_k127_8909680_1 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 0.0 1206.0
HKD3_k127_8909680_10 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 638.0
HKD3_k127_8909680_11 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 597.0
HKD3_k127_8909680_12 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 551.0
HKD3_k127_8909680_13 Cytochrome c oxidase subunit K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 516.0
HKD3_k127_8909680_14 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 506.0
HKD3_k127_8909680_15 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006027 502.0
HKD3_k127_8909680_16 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 481.0
HKD3_k127_8909680_17 phosphoribosylaminoimidazole-succinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 472.0
HKD3_k127_8909680_18 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 481.0
HKD3_k127_8909680_19 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 440.0
HKD3_k127_8909680_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0 1163.0
HKD3_k127_8909680_20 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 442.0
HKD3_k127_8909680_21 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 441.0
HKD3_k127_8909680_22 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 390.0
HKD3_k127_8909680_23 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 392.0
HKD3_k127_8909680_24 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 358.0
HKD3_k127_8909680_25 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 370.0
HKD3_k127_8909680_26 Methyltransferase domain K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 334.0
HKD3_k127_8909680_27 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 316.0
HKD3_k127_8909680_28 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006462 293.0
HKD3_k127_8909680_29 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009573 252.0
HKD3_k127_8909680_3 PEP-utilising enzyme, N-terminal K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 0.0 1050.0
HKD3_k127_8909680_30 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002237 258.0
HKD3_k127_8909680_31 Electron transport protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000167 272.0
HKD3_k127_8909680_32 uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000009135 247.0
HKD3_k127_8909680_33 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000001173 242.0
HKD3_k127_8909680_34 lipase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005256 248.0
HKD3_k127_8909680_35 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000009322 241.0
HKD3_k127_8909680_36 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001204 243.0
HKD3_k127_8909680_37 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000000000000000000008573 213.0
HKD3_k127_8909680_38 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001576 216.0
HKD3_k127_8909680_39 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000004423 190.0
HKD3_k127_8909680_4 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1041.0
HKD3_k127_8909680_40 Integral membrane protein (DUF2244) - - - 0.000000000000000000000000000000000000000000000003186 181.0
HKD3_k127_8909680_41 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000004758 177.0
HKD3_k127_8909680_42 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000000000002754 142.0
HKD3_k127_8909680_43 Chalcone isomerase-like - - - 0.0000000000000000000000000000000001659 149.0
HKD3_k127_8909680_44 Protein of unknown function (DUF2970) - - - 0.00000000000000000000000395 112.0
HKD3_k127_8909680_45 - - - - 0.00000000000000000004139 96.0
HKD3_k127_8909680_5 DNA polymerase III K02342 - 2.7.7.7 9.335e-297 936.0
HKD3_k127_8909680_6 PTS glucose transporter subunit IIBC K02778,K02779 - 2.7.1.199 8.715e-275 856.0
HKD3_k127_8909680_7 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 3.524e-241 770.0
HKD3_k127_8909680_8 Amidohydrolase family K01465 - 3.5.2.3 1.52e-220 715.0
HKD3_k127_8909680_9 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 602.0
HKD3_k127_8941286_0 Cytochrome C biogenesis protein transmembrane region K04084,K08344 - 1.8.1.8 5.697e-280 877.0
HKD3_k127_8941286_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008511 448.0
HKD3_k127_8941286_10 Transposase - - - 0.000004673 49.0
HKD3_k127_8941286_2 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006574 432.0
HKD3_k127_8941286_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 391.0
HKD3_k127_8941286_4 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 286.0
HKD3_k127_8941286_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009051 248.0
HKD3_k127_8941286_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000001356 219.0
HKD3_k127_8941286_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000003002 220.0
HKD3_k127_8941286_8 ATP synthase I chain K02116 - - 0.000000000000000000000000000000000000000000000000000001036 196.0
HKD3_k127_8941286_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000002066 169.0
HKD3_k127_8943430_0 Deoxyribodipyrimidine photo-lyase-related protein K06876 - - 3.411e-222 702.0
HKD3_k127_8943430_1 DNA photolyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 531.0
HKD3_k127_8943430_2 FAD binding domain of DNA photolyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 486.0
HKD3_k127_8943430_3 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 456.0
HKD3_k127_8943430_4 Short-chain dehydrogenase reductase (SDR) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 349.0
HKD3_k127_8943430_5 Peptidase M16 K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 332.0
HKD3_k127_8943430_6 ProQ/FINO family K03607 - - 0.00000000000000000000000000000000000000000000001074 181.0
HKD3_k127_8943430_7 Protein of unknown function, DUF393 - - - 0.000000000000000000000000000000000001495 145.0
HKD3_k127_8943430_8 Uncharacterized protein conserved in bacteria (DUF2256) - - - 0.0000000000000002933 89.0
HKD3_k127_8987688_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.303e-219 691.0
HKD3_k127_8987688_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 385.0
HKD3_k127_8987688_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002178 276.0
HKD3_k127_8987688_3 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000000000000000000000000000000000003348 225.0
HKD3_k127_8987688_4 Protein of unknown function (DUF2818) - - - 0.00000000000000000000000000000000001959 137.0
HKD3_k127_8987688_5 CoA binding domain K09181 - - 0.00000000000000000000000001828 121.0
HKD3_k127_8987688_6 Protein of unknown function (DUF2917) - - - 0.000000000001378 73.0
HKD3_k127_8987688_7 LysR substrate binding domain - - - 0.000002219 50.0
HKD3_k127_9087236_0 aminopeptidase N K01256 - 3.4.11.2 0.0 1350.0
HKD3_k127_9087236_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0 1091.0
HKD3_k127_9087236_10 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 413.0
HKD3_k127_9087236_11 ATPases associated with a variety of cellular activities K10554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 404.0
HKD3_k127_9087236_12 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 396.0
HKD3_k127_9087236_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000742 263.0
HKD3_k127_9087236_14 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002796 271.0
HKD3_k127_9087236_15 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007461 248.0
HKD3_k127_9087236_16 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000003379 187.0
HKD3_k127_9087236_17 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000000000000008674 150.0
HKD3_k127_9087236_18 - - - - 0.00000000000008061 76.0
HKD3_k127_9087236_2 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 6.37e-322 991.0
HKD3_k127_9087236_3 AMP-binding enzyme K01895 - 6.2.1.1 7.793e-280 869.0
HKD3_k127_9087236_4 Putative nucleotidyltransferase substrate binding domain K07182 - - 1.052e-228 724.0
HKD3_k127_9087236_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 1.244e-196 616.0
HKD3_k127_9087236_6 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 2.861e-195 611.0
HKD3_k127_9087236_7 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K10552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 541.0
HKD3_k127_9087236_8 Belongs to the binding-protein-dependent transport system permease family K10440,K10553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006933 536.0
HKD3_k127_9087236_9 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 443.0
HKD3_k127_9091026_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1104.0
HKD3_k127_9091026_1 type II and III secretion system protein K02666 - - 1.203e-306 966.0
HKD3_k127_9091026_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 5.552e-209 659.0
HKD3_k127_9091026_3 pilus assembly protein PilM K02662 - - 1.436e-200 629.0
HKD3_k127_9091026_4 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 488.0
HKD3_k127_9091026_5 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 317.0
HKD3_k127_9091026_6 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005318 265.0
HKD3_k127_9091026_7 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003335 266.0
HKD3_k127_9091026_8 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000000000000000000001003 233.0
HKD3_k127_9091026_9 Belongs to the frataxin family K06202 - - 0.00000000000000000000000000000000005918 153.0
HKD3_k127_9241817_0 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 415.0
HKD3_k127_9241817_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 392.0
HKD3_k127_9241817_2 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 340.0
HKD3_k127_9241817_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 340.0
HKD3_k127_9241817_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006855 264.0
HKD3_k127_9241817_5 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000001752 174.0
HKD3_k127_9241817_6 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000002674 177.0
HKD3_k127_9241817_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000004278 89.0
HKD3_k127_9241817_8 - - - - 0.0000000000000000005717 91.0
HKD3_k127_9256331_0 helicase K03657 - 3.6.4.12 0.0 1012.0
HKD3_k127_9256331_1 Histidine kinase K02482 - 2.7.13.3 1.911e-290 939.0
HKD3_k127_9256331_2 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 3.246e-195 614.0
HKD3_k127_9256331_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 558.0
HKD3_k127_9256331_4 Fad dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 499.0
HKD3_k127_9256331_5 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 317.0
HKD3_k127_9256331_6 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000115 254.0
HKD3_k127_9295079_0 Protein export membrane protein K19594 - - 0.0 1277.0
HKD3_k127_9295079_1 Domain of unknown function (DUF5117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 367.0
HKD3_k127_9295079_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18901 - - 0.000000000000000000000000000000000000000000000000000000000000000344 240.0
HKD3_k127_9295079_3 Outer membrane efflux protein K19593 - - 0.00000000000000000000000000000000000000000000000000001283 206.0
HKD3_k127_9295079_4 extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000007894 186.0
HKD3_k127_9295079_6 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000001455 82.0
HKD3_k127_9295079_7 Protein conserved in bacteria - - - 0.00000000000005696 83.0
HKD3_k127_9295079_8 - - - - 0.0001357 50.0
HKD3_k127_98095_0 Alkyl hydroperoxide reductase K03387 - - 2.777e-265 829.0
HKD3_k127_98095_1 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 3.821e-235 730.0
HKD3_k127_98095_10 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 354.0
HKD3_k127_98095_11 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 358.0
HKD3_k127_98095_12 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007046 348.0
HKD3_k127_98095_13 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001264 279.0
HKD3_k127_98095_14 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002466 268.0
HKD3_k127_98095_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003804 245.0
HKD3_k127_98095_16 FR47-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000003039 239.0
HKD3_k127_98095_17 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000003026 213.0
HKD3_k127_98095_18 PFAM Cytochrome C - - - 0.00000000000000000000000000000000000000001782 178.0
HKD3_k127_98095_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 609.0
HKD3_k127_98095_3 PFAM aminotransferase, class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007654 533.0
HKD3_k127_98095_4 Aldose 1-epimerase K01785 - 5.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 430.0
HKD3_k127_98095_5 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 402.0
HKD3_k127_98095_6 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 385.0
HKD3_k127_98095_7 SMP-30 Gluconolaconase K13874,K14274 - 3.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 394.0
HKD3_k127_98095_8 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 366.0
HKD3_k127_98095_9 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 343.0