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Overview

ID MAG01872
Name HKD3_bin.69
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Limnocylindria
Order Limnocylindrales
Family CSP1-4
Genus DASVZT01
Species
Assembly information
Completeness (%) 82.28
Contamination (%) 0.66
GC content (%) 72.0
N50 (bp) 9,365
Genome size (bp) 2,770,612

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2449

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_100804_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 606.0
HKD3_k127_100804_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 369.0
HKD3_k127_100804_10 lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.000000000000000000000006676 118.0
HKD3_k127_100804_11 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000001848 118.0
HKD3_k127_100804_12 Lipid A biosynthesis K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.000000000000000000004883 108.0
HKD3_k127_100804_13 PFAM glycosyl transferase family 39 K00728 - 2.4.1.109 0.0001324 57.0
HKD3_k127_100804_14 amine dehydrogenase activity - - - 0.000796 53.0
HKD3_k127_100804_2 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009108 325.0
HKD3_k127_100804_3 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.000000000000000000000000000000000000000000000000000000000000009097 231.0
HKD3_k127_100804_4 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001062 231.0
HKD3_k127_100804_5 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000001307 169.0
HKD3_k127_100804_6 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000003832 162.0
HKD3_k127_100804_7 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000009215 150.0
HKD3_k127_100804_8 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000003677 127.0
HKD3_k127_100804_9 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000000000000000001337 126.0
HKD3_k127_1015478_0 ABC transporter K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 360.0
HKD3_k127_1015478_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000001935 256.0
HKD3_k127_1078386_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007472 503.0
HKD3_k127_1078386_1 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008699 441.0
HKD3_k127_1078386_2 Glutamine synthetase N-terminal domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 413.0
HKD3_k127_1078386_3 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 389.0
HKD3_k127_1078386_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000009331 230.0
HKD3_k127_1078386_5 PFAM cyclase family protein - - - 0.00000000000000000000000000000000000000000000000000009776 194.0
HKD3_k127_1078386_6 VIT family - - - 0.000000000000000000000000000000000000000000000000049 192.0
HKD3_k127_1078386_7 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000001549 151.0
HKD3_k127_1078386_8 Trypsin-like peptidase domain K04771 - 3.4.21.107 0.000000000000000000000000005351 113.0
HKD3_k127_1078386_9 cysteine-tRNA ligase activity - - - 0.00000000004056 74.0
HKD3_k127_110300_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 8.855e-222 695.0
HKD3_k127_110300_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.092e-204 648.0
HKD3_k127_110300_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003994 270.0
HKD3_k127_110300_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000001185 140.0
HKD3_k127_110300_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000002601 114.0
HKD3_k127_110300_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000002391 78.0
HKD3_k127_1175687_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 346.0
HKD3_k127_1175687_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000003632 190.0
HKD3_k127_1175687_2 Belongs to the 'phage' integrase family. XerC subfamily K04763 GO:0008150,GO:0040007 - 0.0002067 52.0
HKD3_k127_1208384_0 radical SAM K06871 GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006624 608.0
HKD3_k127_1208384_1 sulphate transporter K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 610.0
HKD3_k127_1208384_2 Major Facilitator Superfamily - - - 0.00000000000000002379 96.0
HKD3_k127_1208384_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000009924 64.0
HKD3_k127_1220288_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.334e-194 644.0
HKD3_k127_1220288_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0008150,GO:0040007 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004757 505.0
HKD3_k127_1220288_2 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 467.0
HKD3_k127_1220288_3 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 336.0
HKD3_k127_1220288_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 324.0
HKD3_k127_1220288_5 AICARFT/IMPCHase bienzyme K00602 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 294.0
HKD3_k127_1220288_6 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001932 276.0
HKD3_k127_1220288_7 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001492 275.0
HKD3_k127_1220288_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000009584 74.0
HKD3_k127_1221236_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 539.0
HKD3_k127_1221236_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 377.0
HKD3_k127_1221236_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 331.0
HKD3_k127_1221236_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 304.0
HKD3_k127_1221236_4 Histidine biosynthesis bifunctional protein HisIE K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000006018 182.0
HKD3_k127_1221236_5 alkylbase DNA N-glycosylase activity K03652 - 3.2.2.21 0.000000000000000000000000000000000000143 155.0
HKD3_k127_1221236_6 Colicin V production protein K03558 - - 0.000001243 58.0
HKD3_k127_1221236_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0004604 43.0
HKD3_k127_1221596_0 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 298.0
HKD3_k127_1221596_1 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001154 264.0
HKD3_k127_1221596_2 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000004333 241.0
HKD3_k127_1221596_3 Cobalamin B12-binding K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000007315 196.0
HKD3_k127_1221596_4 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.0000000000000000000000000000000002381 138.0
HKD3_k127_1221596_5 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000007234 134.0
HKD3_k127_1223769_0 Alcohol dehydrogenase GroES-like domain K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 513.0
HKD3_k127_1223769_1 Alpha-amylase domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 520.0
HKD3_k127_1223769_10 Metal-dependent hydrolases of the beta-lactamase superfamily III - GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 - 0.0000000000000000000003721 102.0
HKD3_k127_1223769_11 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000000000007677 101.0
HKD3_k127_1223769_12 Protein of unknown function (DUF3105) - - - 0.00000000000000000087 97.0
HKD3_k127_1223769_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 485.0
HKD3_k127_1223769_3 PFAM Binding-protein-dependent transport system inner membrane component K02025,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 362.0
HKD3_k127_1223769_4 PFAM Bacterial extracellular solute-binding protein K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 364.0
HKD3_k127_1223769_5 PFAM Binding-protein-dependent transport system inner membrane component K15772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 335.0
HKD3_k127_1223769_6 periplasmic binding protein LacI transcriptional regulator K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005015 281.0
HKD3_k127_1223769_7 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16164 - 3.7.1.5 0.000000000000000000000000000000000000000000000000000000000001285 221.0
HKD3_k127_1223769_8 PHP domain K04486 - 3.1.3.15 0.00000000000000000000000000000001194 147.0
HKD3_k127_1223769_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000001447 134.0
HKD3_k127_1240087_0 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 391.0
HKD3_k127_1240087_1 response to heat K03668 - - 0.00000000000000000000000004929 119.0
HKD3_k127_1241544_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 599.0
HKD3_k127_1241544_1 Nitroreductase family - - - 0.000000000000000000000000000000000007875 148.0
HKD3_k127_1241544_2 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000001546 138.0
HKD3_k127_1241544_3 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000008167 114.0
HKD3_k127_1245605_0 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003748 252.0
HKD3_k127_1256604_0 VIT family - - - 0.0000000000000000000000000000000000000000001226 164.0
HKD3_k127_1256604_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000005551 134.0
HKD3_k127_1256604_2 asnC family K03719 - - 0.000000000000000000000000000002837 125.0
HKD3_k127_1256604_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000001446 98.0
HKD3_k127_1256604_4 An anti-sigma factor for extracytoplasmic function (ECF) sigma factor SigK. ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut extracytoplasmically (site-1 protease, S1P), then within the membrane itself (site-2 protease, S2P, Rip1), while cytoplasmic proteases finish degrading the regulatory protein, liberating the sigma factor - - - 0.0001261 53.0
HKD3_k127_1257231_0 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003587 410.0
HKD3_k127_1257231_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 384.0
HKD3_k127_1257231_2 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001253 237.0
HKD3_k127_1257374_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 3.648e-234 748.0
HKD3_k127_1257374_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K12527 - 1.97.1.9 2.234e-198 637.0
HKD3_k127_1257374_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 450.0
HKD3_k127_1257374_3 xanthine dehydrogenase activity K13479 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000004307 209.0
HKD3_k127_1257374_4 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000067 172.0
HKD3_k127_1257374_5 Molybdopterin-binding domain of aldehyde dehydrogenase K20448 - 1.17.1.5 0.00002196 47.0
HKD3_k127_1280316_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 616.0
HKD3_k127_1280316_1 phenylalanyl-tRNA synthetase (beta subunit) K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 539.0
HKD3_k127_1280316_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 357.0
HKD3_k127_1280316_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000005515 200.0
HKD3_k127_1280316_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000002158 138.0
HKD3_k127_1280316_5 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000001552 59.0
HKD3_k127_1287892_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 443.0
HKD3_k127_1287892_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000476 207.0
HKD3_k127_1287892_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000002867 182.0
HKD3_k127_1287892_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000002424 140.0
HKD3_k127_1287892_4 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000002177 85.0
HKD3_k127_1289285_0 Kelch - - - 0.00000000000000000000000000000000000000000002974 179.0
HKD3_k127_1304084_0 PFAM Sodium calcium exchanger membrane region K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001861 283.0
HKD3_k127_1304084_1 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000002701 203.0
HKD3_k127_1304084_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000001276 76.0
HKD3_k127_1311515_0 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 476.0
HKD3_k127_1311515_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 350.0
HKD3_k127_1311515_2 Membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 317.0
HKD3_k127_1311515_3 DNA-binding transcription factor activity K03710 - - 0.0000000000000000000000000000000001496 145.0
HKD3_k127_1311515_4 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000002886 123.0
HKD3_k127_1311515_5 - - - - 0.0000000000000000000000000003268 121.0
HKD3_k127_1316370_0 Mycobacterial 4 TMS phage holin, superfamily IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 481.0
HKD3_k127_1316370_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 447.0
HKD3_k127_1316370_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000006576 206.0
HKD3_k127_1356086_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004039 284.0
HKD3_k127_1356086_1 histidine kinase HAMP region domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004483 262.0
HKD3_k127_1356086_2 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000008744 237.0
HKD3_k127_1356086_3 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000007128 219.0
HKD3_k127_1356086_4 diacylglycerol kinase - - - 0.000000000000000000000000000008829 136.0
HKD3_k127_1356086_5 - - - - 0.0000000000000862 81.0
HKD3_k127_1356086_6 Short C-terminal domain K08982 - - 0.0000005297 56.0
HKD3_k127_1362597_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.105e-234 764.0
HKD3_k127_1362597_1 Beta-eliminating lyase K01667,K01668 - 4.1.99.1,4.1.99.2 1.132e-232 727.0
HKD3_k127_1362597_10 Cupin superfamily (DUF985) K09705 - - 0.0000000000000000000000000000000000000000000002812 181.0
HKD3_k127_1362597_11 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000001366 162.0
HKD3_k127_1362597_12 AMMECR1 K09141 - - 0.0000000000000000000000127 102.0
HKD3_k127_1362597_13 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000001082 98.0
HKD3_k127_1362597_14 TAP-like protein - - - 0.000000000000000002097 88.0
HKD3_k127_1362597_15 Protein of unknown function (DUF1294) - - - 0.0000000000005139 73.0
HKD3_k127_1362597_16 Cold shock K03704 - - 0.00000001667 65.0
HKD3_k127_1362597_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000002186 62.0
HKD3_k127_1362597_18 N-acetyltransferase - - - 0.00004235 55.0
HKD3_k127_1362597_2 L-carnitine dehydratase bile acid-inducible protein F K07749,K08298 - 2.8.3.16,2.8.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 459.0
HKD3_k127_1362597_3 beta-1,4-mannooligosaccharide phosphorylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 429.0
HKD3_k127_1362597_4 Alanine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 332.0
HKD3_k127_1362597_5 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 317.0
HKD3_k127_1362597_6 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001998 284.0
HKD3_k127_1362597_7 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004998 263.0
HKD3_k127_1362597_8 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000004972 221.0
HKD3_k127_1362597_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000004306 205.0
HKD3_k127_1369436_0 aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 447.0
HKD3_k127_1369436_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007779 275.0
HKD3_k127_1369436_2 Histidine kinase A domain protein - - - 0.00000000000000000000000000000000000001226 161.0
HKD3_k127_1369436_3 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000004181 161.0
HKD3_k127_1369436_4 Rhodanese-related sulfurtransferase - - - 0.00000000000000000001051 100.0
HKD3_k127_1374132_0 DNA primase, small subunit K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 492.0
HKD3_k127_1374132_1 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000006661 165.0
HKD3_k127_1374132_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000005251 152.0
HKD3_k127_1374132_3 Protein of unknown function (DUF861) - - - 0.0002152 45.0
HKD3_k127_1374132_4 Response regulator receiver domain protein K07670 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016310,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0008554 47.0
HKD3_k127_1400677_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000539 247.0
HKD3_k127_1400677_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000002003 202.0
HKD3_k127_143280_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 393.0
HKD3_k127_143280_1 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 338.0
HKD3_k127_143280_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005177 286.0
HKD3_k127_143280_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000001376 259.0
HKD3_k127_143280_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000007707 236.0
HKD3_k127_143280_5 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000004146 223.0
HKD3_k127_143280_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000001826 216.0
HKD3_k127_143280_7 PFAM Uncharacterised protein family UPF0047 - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000607 164.0
HKD3_k127_143280_8 Protein of unknown function (DUF1290) - - - 0.000000000000000000000000000008365 121.0
HKD3_k127_143280_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0002692 53.0
HKD3_k127_1458305_0 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000001696 233.0
HKD3_k127_1458305_1 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000003105 152.0
HKD3_k127_1458919_0 DEAD/H associated K03724 - - 0.0 1542.0
HKD3_k127_1458919_1 PFAM histone deacetylase superfamily K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 335.0
HKD3_k127_1458919_2 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 244.0
HKD3_k127_1458919_3 Belongs to the FPG family K05522 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000003239 240.0
HKD3_k127_1458919_4 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000001064 164.0
HKD3_k127_1458919_5 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000009061 157.0
HKD3_k127_1458919_6 - - - - 0.0000000000000000006491 101.0
HKD3_k127_1458919_7 DoxX K16937 - 1.8.5.2 0.000000000000001751 86.0
HKD3_k127_1458919_8 - - - - 0.000000004373 68.0
HKD3_k127_1458919_9 glutamine amidotransferase K07008 - 3.5.1.118 0.00004727 54.0
HKD3_k127_1477179_0 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 523.0
HKD3_k127_1477179_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 463.0
HKD3_k127_1477179_2 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000005656 246.0
HKD3_k127_1477179_3 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000002366 165.0
HKD3_k127_1477179_4 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000006967 155.0
HKD3_k127_1477179_6 Cytochrome C biogenesis protein - - - 0.0000000000000000000000003793 111.0
HKD3_k127_1477179_7 Rhodanese Homology Domain - - - 0.000000000000000000000005707 102.0
HKD3_k127_1484559_0 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 491.0
HKD3_k127_1484559_1 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 342.0
HKD3_k127_1484559_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0016740,GO:0016765,GO:0019899,GO:0030312,GO:0035375,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.5.1.6 0.00000293 53.0
HKD3_k127_1506058_0 Alpha-amylase domain K05343 - 3.2.1.1,5.4.99.16 1.668e-292 934.0
HKD3_k127_1506058_1 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.037e-223 714.0
HKD3_k127_1506058_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 561.0
HKD3_k127_1522595_0 PFAM Receptor family ligand binding region K01999,K11954 - - 0.0000000000000000000000000000000000000000000000000000000004143 220.0
HKD3_k127_1522595_1 NYN domain - - - 0.00000000000000000000000000000000001051 154.0
HKD3_k127_1522595_2 PFAM AAA ATPase central domain protein - - - 0.0001057 51.0
HKD3_k127_1539264_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 7.804e-231 745.0
HKD3_k127_1539264_1 Elongation factor G C-terminus K06207 - - 2.69e-222 707.0
HKD3_k127_1539264_2 cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 382.0
HKD3_k127_1539264_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 379.0
HKD3_k127_1539264_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 320.0
HKD3_k127_1539264_5 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000006896 173.0
HKD3_k127_1539264_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000718 136.0
HKD3_k127_1539264_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000006787 98.0
HKD3_k127_1539264_8 Baseplate J-like protein K01218 - 3.2.1.78 0.00000000651 69.0
HKD3_k127_1539264_9 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.0000006241 59.0
HKD3_k127_1554252_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 300.0
HKD3_k127_1554252_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001348 291.0
HKD3_k127_1554252_2 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000008305 259.0
HKD3_k127_1554252_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000002003 223.0
HKD3_k127_1554252_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000002002 70.0
HKD3_k127_1558677_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 352.0
HKD3_k127_1558677_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000001124 184.0
HKD3_k127_1558677_2 Putative glycolipid-binding - - - 0.0000000000000000000000000000000000000001219 157.0
HKD3_k127_1558677_3 Protein of unknown function (DUF4232) - - - 0.00000000000000009835 91.0
HKD3_k127_1558677_4 - - - - 0.0000005956 57.0
HKD3_k127_157208_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 516.0
HKD3_k127_157208_1 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 423.0
HKD3_k127_157208_10 4Fe-4S single cluster domain - - - 0.00000000000000000001623 99.0
HKD3_k127_157208_2 Zn-dependent dipeptidase, microsomal dipeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 387.0
HKD3_k127_157208_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 308.0
HKD3_k127_157208_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000003367 270.0
HKD3_k127_157208_5 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000001362 250.0
HKD3_k127_157208_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004671 250.0
HKD3_k127_157208_7 nitric oxide dioxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000266 203.0
HKD3_k127_157208_8 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000111 170.0
HKD3_k127_157208_9 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000001318 121.0
HKD3_k127_157247_0 PhoD-like phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 614.0
HKD3_k127_157247_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 529.0
HKD3_k127_157247_10 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000128 219.0
HKD3_k127_157247_11 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000006095 213.0
HKD3_k127_157247_12 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000005308 198.0
HKD3_k127_157247_13 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000004017 190.0
HKD3_k127_157247_14 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000003474 169.0
HKD3_k127_157247_15 CorA-like Mg2+ transporter protein - - - 0.0000000000000000000000000000000000003487 154.0
HKD3_k127_157247_16 polysaccharide biosynthetic process K01992 - - 0.00000000000000000000000000000000001855 154.0
HKD3_k127_157247_17 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000001808 153.0
HKD3_k127_157247_18 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000002452 134.0
HKD3_k127_157247_19 Diacylglycerol kinase K19302 - 3.6.1.27 0.000000000000000000000000002177 130.0
HKD3_k127_157247_2 Glycosyltransferase family 20 K00697 - 2.4.1.15,2.4.1.347 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 321.0
HKD3_k127_157247_20 AI-2E family transporter - - - 0.000000000000000000000005759 115.0
HKD3_k127_157247_21 - - - - 0.00000000000000000000004855 100.0
HKD3_k127_157247_22 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000005608 85.0
HKD3_k127_157247_23 Transglycosylase associated protein - - - 0.000000005228 69.0
HKD3_k127_157247_24 Protein of unknown function (DUF1211) - - - 0.000000007509 60.0
HKD3_k127_157247_25 Glycosyl transferases group 1 - - - 0.00000006915 64.0
HKD3_k127_157247_26 - - - - 0.00002013 55.0
HKD3_k127_157247_27 - - - - 0.00005197 56.0
HKD3_k127_157247_28 - - - - 0.0001503 53.0
HKD3_k127_157247_29 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071944 - 0.0002416 44.0
HKD3_k127_157247_3 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 292.0
HKD3_k127_157247_4 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 282.0
HKD3_k127_157247_5 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007585 281.0
HKD3_k127_157247_6 Glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002763 261.0
HKD3_k127_157247_7 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000000000000000000000000000000000000000000000000000000000004657 243.0
HKD3_k127_157247_8 Major intrinsic protein - - - 0.00000000000000000000000000000000000000000000000000000000001345 216.0
HKD3_k127_157247_9 beta-galactosidase activity K01219,K21000 - 3.2.1.81 0.00000000000000000000000000000000000000000000000000000000003993 222.0
HKD3_k127_1587861_0 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000003669 175.0
HKD3_k127_1587861_1 - - - - 0.0000000000000000007525 91.0
HKD3_k127_1587861_2 response regulator, receiver - - - 0.00000000002238 65.0
HKD3_k127_1587861_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000004135 69.0
HKD3_k127_1600986_0 Phage portal protein - - - 0.00000000000000000000000000000000000004142 162.0
HKD3_k127_1600986_2 Terminase - - - 0.000000000000000000000000001574 124.0
HKD3_k127_1600986_3 YqaJ-like viral recombinase domain - - - 0.00000000000000002561 94.0
HKD3_k127_1600986_4 Phage prohead protease, HK97 family K06904 - - 0.0000000000000003239 92.0
HKD3_k127_1600986_5 Prophage tail length tape measure protein - - - 0.000000005627 69.0
HKD3_k127_1600986_6 Pectate lyase superfamily protein - - - 0.000001874 62.0
HKD3_k127_1628060_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 473.0
HKD3_k127_1628060_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007716 290.0
HKD3_k127_1628060_2 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000001326 227.0
HKD3_k127_1628060_3 Ribosomal protein S16 K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000172 120.0
HKD3_k127_1628060_4 Belongs to the UPF0109 family K06960 - - 0.000000000000000000004449 94.0
HKD3_k127_1628060_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.0000000000000000375 90.0
HKD3_k127_1628060_6 Protein of unknown function (DUF3352) - - - 0.00000000000001784 87.0
HKD3_k127_1628069_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 617.0
HKD3_k127_1628069_1 TIGRFAM 6-phosphogluconate dehydrogenase, decarboxylating K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 365.0
HKD3_k127_1628069_2 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000000002134 162.0
HKD3_k127_1628069_3 Glucose-6-phosphate dehydrogenase subunit - - - 0.00000000000000000000000000000001853 143.0
HKD3_k127_1628069_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000029 140.0
HKD3_k127_1628069_5 EVE domain - - - 0.0000000000002685 79.0
HKD3_k127_1636496_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 400.0
HKD3_k127_1636496_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 338.0
HKD3_k127_1636496_2 TIGRFAM Dyp-type peroxidase family K07223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008633 281.0
HKD3_k127_1636496_3 cyclic nucleotide binding K10914 - - 0.00000000000000004554 94.0
HKD3_k127_1636496_4 Domain of unknown function (DUF1992) - - - 0.00002593 48.0
HKD3_k127_1646713_1 helix_turn_helix, mercury resistance - - - 0.0000000000000000003991 98.0
HKD3_k127_1728754_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 455.0
HKD3_k127_1728754_1 Putative FMN-binding domain K07734 - - 0.00000003595 56.0
HKD3_k127_1753583_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.559e-271 844.0
HKD3_k127_1753583_1 Heat shock 70 kDa protein K04043 - - 2.821e-252 806.0
HKD3_k127_1753583_10 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000635 267.0
HKD3_k127_1753583_11 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007926 260.0
HKD3_k127_1753583_12 Carboxylesterase family K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001283 243.0
HKD3_k127_1753583_13 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000001185 235.0
HKD3_k127_1753583_14 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000007557 231.0
HKD3_k127_1753583_15 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000007531 150.0
HKD3_k127_1753583_16 GatB Yqey domain protein K09117 - - 0.00000000000000000000000000000001065 136.0
HKD3_k127_1753583_17 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000154 141.0
HKD3_k127_1753583_18 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000001369 120.0
HKD3_k127_1753583_19 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000255 93.0
HKD3_k127_1753583_2 ABC transporter K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 441.0
HKD3_k127_1753583_20 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001627 82.0
HKD3_k127_1753583_21 Binds directly to 16S ribosomal RNA K02968 - - 0.00000006339 61.0
HKD3_k127_1753583_22 EamA-like transporter family - - - 0.000004551 58.0
HKD3_k127_1753583_23 CAAX protease self-immunity K07052 - - 0.0003126 51.0
HKD3_k127_1753583_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 404.0
HKD3_k127_1753583_4 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 398.0
HKD3_k127_1753583_5 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 329.0
HKD3_k127_1753583_6 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 322.0
HKD3_k127_1753583_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 304.0
HKD3_k127_1753583_8 PFAM Integrase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
HKD3_k127_1753583_9 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000003407 284.0
HKD3_k127_179861_0 Zinc-binding dehydrogenase K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 295.0
HKD3_k127_179861_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000008381 282.0
HKD3_k127_179861_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000765 264.0
HKD3_k127_179861_3 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000001067 246.0
HKD3_k127_179861_4 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000008155 219.0
HKD3_k127_179861_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000001148 182.0
HKD3_k127_179861_6 Methyltransferase domain K06987 - - 0.00000000000000000000000000000000000000008853 160.0
HKD3_k127_179861_7 - - - - 0.0000000000000000000000000000743 128.0
HKD3_k127_179861_8 conserved protein, contains double-stranded beta-helix domain - - - 0.0000000000000000001554 93.0
HKD3_k127_179861_9 serine-type aminopeptidase activity K02030,K14475 - - 0.0000000002287 70.0
HKD3_k127_1801116_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 359.0
HKD3_k127_1801116_1 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 344.0
HKD3_k127_1801116_10 Phosphoglycerate mutase family K08296 - - 0.0000000000000000002499 99.0
HKD3_k127_1801116_2 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 325.0
HKD3_k127_1801116_3 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000288 264.0
HKD3_k127_1801116_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001988 267.0
HKD3_k127_1801116_5 binding-protein-dependent transport systems inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000001314 224.0
HKD3_k127_1801116_6 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000148 159.0
HKD3_k127_1801116_7 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000001767 153.0
HKD3_k127_1801116_8 Uncharacterized ACR, COG1993 K09137 - - 0.000000000000000000000001205 105.0
HKD3_k127_1801116_9 transcriptional regulator K03892 - - 0.00000000000000000000006937 102.0
HKD3_k127_1839252_0 PFAM pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 308.0
HKD3_k127_1839252_1 Aldo/keto reductase family K00064 - 1.1.1.122 0.00000000000000000000000000000000000000000000000002184 192.0
HKD3_k127_1839252_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000008844 92.0
HKD3_k127_18434_0 Type II/IV secretion system protein K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 539.0
HKD3_k127_18434_1 catalyzes the conversion of pyrimidines to 5,6-dihydro compounds in pyrimidine degradation K17723 - 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 524.0
HKD3_k127_18434_10 DNA-binding protein - - - 0.0000000000000000000000000004775 121.0
HKD3_k127_18434_11 Required for the activity of the bacterial periplasmic transport system of putrescine K11073 - - 0.0000006466 52.0
HKD3_k127_18434_2 Acetamidase formamidase K01455 - 3.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 360.0
HKD3_k127_18434_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 359.0
HKD3_k127_18434_4 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003289 280.0
HKD3_k127_18434_5 3-demethylubiquinone-9 3-methyltransferase K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000591 234.0
HKD3_k127_18434_6 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000002183 223.0
HKD3_k127_18434_7 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000001026 171.0
HKD3_k127_18434_8 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000003671 163.0
HKD3_k127_18434_9 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000002591 160.0
HKD3_k127_1895539_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 589.0
HKD3_k127_1895539_1 - - - - 0.0003273 52.0
HKD3_k127_1919554_0 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000006716 149.0
HKD3_k127_1919554_1 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000001454 95.0
HKD3_k127_1919554_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000001558 68.0
HKD3_k127_1959135_0 PFAM ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002787 277.0
HKD3_k127_1959135_1 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000003053 171.0
HKD3_k127_2032349_0 Domain of unknown function (DUF4445) - - - 2.56e-252 792.0
HKD3_k127_2032349_1 Trimethylamine methyltransferase (MTTB) - - - 5.823e-238 750.0
HKD3_k127_2032349_10 cyclic nucleotide binding K09766,K10914 - - 0.000000000000000001739 98.0
HKD3_k127_2032349_11 cGMP-dependent protein kinase activity K07376,K19477 - 2.7.11.12 0.000000000000157 82.0
HKD3_k127_2032349_2 Phosphoesterase family - - - 7.458e-219 695.0
HKD3_k127_2032349_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 528.0
HKD3_k127_2032349_4 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 362.0
HKD3_k127_2032349_5 Cys/Met metabolism PLP-dependent enzyme K01760 GO:0000096,GO:0000098,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004121,GO:0006082,GO:0006090,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006520,GO:0006534,GO:0006725,GO:0006790,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009093,GO:0009987,GO:0016054,GO:0016829,GO:0016846,GO:0019448,GO:0019450,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044273,GO:0044281,GO:0044282,GO:0046395,GO:0046439,GO:0046483,GO:0047804,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1990414 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 344.0
HKD3_k127_2032349_6 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000001266 261.0
HKD3_k127_2032349_7 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.000000000000000000000000000000000000000000000000003109 201.0
HKD3_k127_2032349_8 xyloglucan:xyloglucosyl transferase activity K01216 - 3.2.1.73 0.000000000000000000000000000000000000000000000002973 188.0
HKD3_k127_2032349_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000002582 152.0
HKD3_k127_2059689_0 Pfam Sulfatase K01130 - 3.1.6.1 0.0 1133.0
HKD3_k127_2059689_1 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 401.0
HKD3_k127_2059689_2 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 364.0
HKD3_k127_2059689_3 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000395 230.0
HKD3_k127_2059689_4 - - - - 0.000000000000000000000000000000000000000000000002889 177.0
HKD3_k127_2059689_5 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000000000002949 114.0
HKD3_k127_2059689_6 Spt4/RpoE2 zinc finger K01090 - 3.1.3.16 0.000000000000000000001146 109.0
HKD3_k127_2059689_7 Fusaric acid resistance protein-like - - - 0.00009644 55.0
HKD3_k127_212781_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 578.0
HKD3_k127_212781_1 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 396.0
HKD3_k127_21562_0 PFAM glycosyl transferase, family 51 - - - 0.00000000000000000000000000000000000000000000000000000000191 225.0
HKD3_k127_21562_1 Lysin motif - - - 0.000000191 59.0
HKD3_k127_2159302_0 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000007562 140.0
HKD3_k127_2159302_1 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K03496,K22491 - - 0.00000000000000000000003907 108.0
HKD3_k127_219089_0 Abc transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000001053 215.0
HKD3_k127_219089_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00002287 46.0
HKD3_k127_220969_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 477.0
HKD3_k127_220969_1 Methylene-tetrahydrofolate reductase C terminal K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 470.0
HKD3_k127_220969_10 - - - - 0.00000000000000000000000000000000000000000000005228 190.0
HKD3_k127_220969_11 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000001316 138.0
HKD3_k127_220969_12 - K01992 - - 0.000000000000000000000000000002505 140.0
HKD3_k127_220969_13 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000002876 111.0
HKD3_k127_220969_14 Conserved protein containing a Zn-ribbon-like motif - - - 0.00000000000000000007659 97.0
HKD3_k127_220969_15 CYTH K01768 - 4.6.1.1 0.000000000003744 74.0
HKD3_k127_220969_2 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 406.0
HKD3_k127_220969_3 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 383.0
HKD3_k127_220969_4 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 326.0
HKD3_k127_220969_5 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000009614 271.0
HKD3_k127_220969_6 Domain of unknown function (DUF427) - - - 0.000000000000000000000000000000000000000000000000000000000000001789 222.0
HKD3_k127_220969_7 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.00000000000000000000000000000000000000000000000000000000000004776 236.0
HKD3_k127_220969_8 hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000009538 223.0
HKD3_k127_220969_9 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000005663 227.0
HKD3_k127_221570_0 PFAM Integrase, catalytic core - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 438.0
HKD3_k127_221570_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 386.0
HKD3_k127_221570_2 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004394 228.0
HKD3_k127_221570_3 NHL repeat - - - 0.000000000000000000000000000000000000000000000000004606 201.0
HKD3_k127_221570_4 phospholipase C K01114 - 3.1.4.3 0.000000000000000000000000000000000000000002218 174.0
HKD3_k127_221570_5 ATP-NAD AcoX kinase - - - 0.00000000000000000000000000000000000000001069 160.0
HKD3_k127_221570_6 SnoaL-like domain - - - 0.000000000000000000264 94.0
HKD3_k127_221570_7 Helix-turn-helix domain - - - 0.0000000002521 63.0
HKD3_k127_221570_9 GYD domain - - - 0.0005155 46.0
HKD3_k127_224682_0 Acylphosphatase K04656 - - 9.066e-261 832.0
HKD3_k127_224682_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 1.474e-258 810.0
HKD3_k127_224682_10 - - - - 0.00003667 52.0
HKD3_k127_224682_11 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0004414 48.0
HKD3_k127_224682_2 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 444.0
HKD3_k127_224682_3 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 408.0
HKD3_k127_224682_4 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001146 299.0
HKD3_k127_224682_5 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.00000000000000000000000000000000000000000000000004011 204.0
HKD3_k127_224682_6 hydrogenase maturation protease K03605 - - 0.0000000000000000000000000001013 132.0
HKD3_k127_224682_7 HupF/HypC family K04653 - - 0.0000000000000000000000000009764 117.0
HKD3_k127_224682_8 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000008602 93.0
HKD3_k127_224682_9 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000002934 82.0
HKD3_k127_2321980_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 487.0
HKD3_k127_2321980_1 Uridine phosphorylase K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000000000000000001474 236.0
HKD3_k127_2321980_2 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000032 198.0
HKD3_k127_2321980_3 Belongs to the phosphoglycerate kinase family K00927 GO:0001871,GO:0002020,GO:0003674,GO:0003824,GO:0004618,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009893,GO:0009986,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019222,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0019899,GO:0030162,GO:0030193,GO:0030195,GO:0030246,GO:0030247,GO:0030312,GO:0031323,GO:0031325,GO:0032101,GO:0032102,GO:0032268,GO:0032270,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043532,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0045862,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048518,GO:0048519,GO:0048522,GO:0048583,GO:0048585,GO:0050789,GO:0050794,GO:0050818,GO:0050819,GO:0050878,GO:0051171,GO:0051173,GO:0051186,GO:0051188,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051917,GO:0051919,GO:0055086,GO:0060255,GO:0061041,GO:0061045,GO:0065007,GO:0065008,GO:0070613,GO:0071704,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0080134,GO:0090407,GO:1900046,GO:1900047,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903034,GO:1903035,GO:1903317,GO:1903319,GO:2001065 2.7.2.3 0.0000000000000000000000000000002465 126.0
HKD3_k127_2321980_4 - - - - 0.0000000000001549 70.0
HKD3_k127_234205_0 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000003316 203.0
HKD3_k127_234205_1 Methyltransferase type 11 - - - 0.00000000000000000000000000000000474 142.0
HKD3_k127_234205_2 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K00320 - 1.5.98.2 0.000000000000000000000000001924 130.0
HKD3_k127_234205_3 acetyltransferase - - - 0.00000000006882 73.0
HKD3_k127_2457062_0 Prolyl oligopeptidase family - - - 1.003e-231 726.0
HKD3_k127_2457062_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 433.0
HKD3_k127_2459040_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 292.0
HKD3_k127_2459040_1 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000001288 184.0
HKD3_k127_2461493_0 PspC domain K03973 - - 0.00000000000678 77.0
HKD3_k127_2461493_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000006658 69.0
HKD3_k127_2461493_2 Putative adhesin - - - 0.000002858 59.0
HKD3_k127_2463050_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 529.0
HKD3_k127_2463050_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002763 243.0
HKD3_k127_2463050_2 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000006221 188.0
HKD3_k127_2463050_3 Archease protein family (MTH1598/TM1083) - - - 0.00002871 54.0
HKD3_k127_2471435_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000272 243.0
HKD3_k127_2471435_1 Protein of unknown function (DUF1385) K09153 - - 0.00000000000000000000000000000000000000000000000000000000005573 215.0
HKD3_k127_247223_0 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000002926 247.0
HKD3_k127_247223_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000001051 239.0
HKD3_k127_2482296_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 326.0
HKD3_k127_2482296_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 310.0
HKD3_k127_2482296_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000001402 259.0
HKD3_k127_2482296_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000277 229.0
HKD3_k127_2482296_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000003963 232.0
HKD3_k127_2482296_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000006437 212.0
HKD3_k127_2482296_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000005367 150.0
HKD3_k127_2482296_7 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000001755 93.0
HKD3_k127_2482296_8 Belongs to the UPF0102 family K07460 - - 0.000001024 59.0
HKD3_k127_2483976_0 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006563,GO:0006564,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 455.0
HKD3_k127_2483976_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 339.0
HKD3_k127_2483976_2 ABC-2 family transporter protein - - - 0.0000000000000000000000000000002082 133.0
HKD3_k127_2487193_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 488.0
HKD3_k127_2487193_1 aldo keto reductase family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001091 239.0
HKD3_k127_2487193_2 ACT domain protein - - - 0.000000000001579 78.0
HKD3_k127_2487193_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000004797 58.0
HKD3_k127_2494394_0 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 1.796e-235 747.0
HKD3_k127_2494394_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 614.0
HKD3_k127_2494394_10 - - - - 0.0000000000000000000000000000000002168 141.0
HKD3_k127_2494394_11 cellulase activity - - - 0.0000000000000000000000000000002351 143.0
HKD3_k127_2494394_12 lysyltransferase activity - - - 0.00000000000000000000004554 112.0
HKD3_k127_2494394_13 Cupin domain - - - 0.00003664 51.0
HKD3_k127_2494394_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0001834 50.0
HKD3_k127_2494394_2 decarboxylase K01593 - 4.1.1.105,4.1.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 531.0
HKD3_k127_2494394_3 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 527.0
HKD3_k127_2494394_4 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 371.0
HKD3_k127_2494394_5 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 313.0
HKD3_k127_2494394_6 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000005496 233.0
HKD3_k127_2494394_7 - - - - 0.0000000000000000000000000000000000000000000000000000000001045 209.0
HKD3_k127_2494394_8 COG4632 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase - - - 0.00000000000000000000000000000000000000000000287 187.0
HKD3_k127_2494394_9 Domain of unknown function (DUF389) - - - 0.0000000000000000000000000000000000000006716 161.0
HKD3_k127_2495535_0 FAD dependent oxidoreductase - - - 8.072e-214 673.0
HKD3_k127_2495535_1 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000008283 263.0
HKD3_k127_2495535_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000314 90.0
HKD3_k127_2495535_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0001101,GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009410,GO:0009415,GO:0009628,GO:0009889,GO:0009891,GO:0009893,GO:0010035,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0042221,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1901700,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000463 80.0
HKD3_k127_2495535_4 Cupin 2, conserved barrel domain protein - - - 0.0003282 49.0
HKD3_k127_2504699_0 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000899 451.0
HKD3_k127_2504699_1 Belongs to the ABC transporter superfamily K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 386.0
HKD3_k127_2504699_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
HKD3_k127_2504699_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 344.0
HKD3_k127_2504699_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000941 276.0
HKD3_k127_2508165_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000006247 252.0
HKD3_k127_2532156_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1207.0
HKD3_k127_2532156_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.845e-231 743.0
HKD3_k127_2532156_10 Helix-turn-helix domain K07729 - - 0.0000000000000000005184 88.0
HKD3_k127_2532156_11 Hemerythrin HHE cation binding domain - - - 0.000000000000000003572 90.0
HKD3_k127_2532156_12 - - - - 0.00000000000000007325 92.0
HKD3_k127_2532156_13 Transcriptional regulator - - - 0.00000000000005207 78.0
HKD3_k127_2532156_14 Hemerythrin HHE cation binding domain - - - 0.00000000000008896 85.0
HKD3_k127_2532156_15 Transcriptional regulator - - - 0.0000000000002032 81.0
HKD3_k127_2532156_16 - - - - 0.00002002 55.0
HKD3_k127_2532156_17 - - - - 0.00007398 52.0
HKD3_k127_2532156_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 460.0
HKD3_k127_2532156_3 Transcriptional regulatory protein, C terminal K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000005816 210.0
HKD3_k127_2532156_4 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000001391 204.0
HKD3_k127_2532156_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000002165 204.0
HKD3_k127_2532156_7 Sulfurtransferase TusA - - - 0.000000000000000000000000827 105.0
HKD3_k127_2532156_8 - K06039,K07092 - - 0.000000000000000000000003729 106.0
HKD3_k127_2532156_9 DsrE/DsrF-like family - - - 0.0000000000000000000605 94.0
HKD3_k127_2532412_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004726 430.0
HKD3_k127_2532412_1 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000181 173.0
HKD3_k127_2532412_2 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000000000002778 138.0
HKD3_k127_2532412_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000187 123.0
HKD3_k127_2532412_4 PFAM zinc finger, SWIM domain protein - - - 0.0000000000000000000000003884 108.0
HKD3_k127_2548661_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000002641 173.0
HKD3_k127_2548661_1 domain protein - - - 0.00007326 55.0
HKD3_k127_2555707_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 613.0
HKD3_k127_2555707_1 oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 317.0
HKD3_k127_2555707_2 PFAM Metallopeptidase family M24 - - - 0.00000000000000000000000000000000000003134 149.0
HKD3_k127_2566093_0 Belongs to the formate--tetrahydrofolate ligase family K01938 GO:0000096,GO:0000097,GO:0000105,GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006520,GO:0006547,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009108,GO:0009110,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0052803,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.3 1.189e-212 691.0
HKD3_k127_2566093_1 PFAM Phenylalanine and histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 499.0
HKD3_k127_2566093_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 493.0
HKD3_k127_2566093_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009198 277.0
HKD3_k127_2566093_4 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000026 198.0
HKD3_k127_2566093_5 PFAM Formiminotransferase-cyclodeaminase - - - 0.000000000000000000000000000000005902 136.0
HKD3_k127_2566093_6 acetyltransferase - - - 0.0007985 53.0
HKD3_k127_2572929_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 1.619e-223 707.0
HKD3_k127_2572929_1 PFAM MMPL domain protein K06994 - - 5.641e-197 640.0
HKD3_k127_2572929_10 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000005095 153.0
HKD3_k127_2572929_11 Thioredoxin - - - 0.0000000000000000000000000000000000007868 153.0
HKD3_k127_2572929_12 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000008753 126.0
HKD3_k127_2572929_13 Anthranilate synthase component I, N terminal region K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000001071 129.0
HKD3_k127_2572929_14 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000002459 104.0
HKD3_k127_2572929_15 transcriptional regulator, Rrf2 family - - - 0.00000000000000000003944 102.0
HKD3_k127_2572929_16 transcriptional regulator, Rrf2 family - - - 0.0000000000000000001073 100.0
HKD3_k127_2572929_17 quinone binding - - - 0.000000000000001333 86.0
HKD3_k127_2572929_2 Multicopper oxidase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 413.0
HKD3_k127_2572929_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005375 366.0
HKD3_k127_2572929_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 353.0
HKD3_k127_2572929_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 317.0
HKD3_k127_2572929_6 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001569 277.0
HKD3_k127_2572929_7 ATPases associated with a variety of cellular activities K09820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004022 259.0
HKD3_k127_2572929_8 Belongs to the bacterial solute-binding protein 9 family K09818 - - 0.000000000000000000000000000000000000000000000000000000003088 213.0
HKD3_k127_2572929_9 ABC 3 transport family K09819 - - 0.0000000000000000000000000000000000000000000001175 176.0
HKD3_k127_2577179_0 Elongator protein 3, MiaB family, Radical SAM K22226,K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000563 263.0
HKD3_k127_2577179_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000562 260.0
HKD3_k127_2577627_0 Aminotransferase, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 447.0
HKD3_k127_2577627_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 439.0
HKD3_k127_2577627_2 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000003636 228.0
HKD3_k127_2577627_3 O-Antigen ligase - - - 0.00001334 58.0
HKD3_k127_2582921_0 Serine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005 578.0
HKD3_k127_2582921_1 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000000000002298 213.0
HKD3_k127_2582921_2 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000002649 205.0
HKD3_k127_2582921_3 ethyl tert-butyl ether degradation - - - 0.0000000000000000000000000000006229 126.0
HKD3_k127_2587630_0 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 380.0
HKD3_k127_2587630_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000268 274.0
HKD3_k127_2587630_2 transferase activity, transferring glycosyl groups K09118,K13693,K21349 - 2.4.1.266,2.4.1.268 0.00000000000000000000000000000000000000000000000000000000000000007707 253.0
HKD3_k127_2587630_3 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 0.000000000003233 75.0
HKD3_k127_258879_0 Molybdenum cofactor synthesis domain protein K00963,K03750 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0071944,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1,2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000003368 272.0
HKD3_k127_258879_1 TIGRFAM integral membrane protein TIGR01906 - - - 0.0000000164 66.0
HKD3_k127_258879_2 Domain of unknown function (DUF4332) - - - 0.00005615 53.0
HKD3_k127_2592290_0 Succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 331.0
HKD3_k127_2592290_1 Ribonuclease H K03469 - 3.1.26.4 0.0000000000000000000000000000000003419 141.0
HKD3_k127_2592290_2 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000001348 125.0
HKD3_k127_2592290_3 Glyco_18 K06306 - - 0.0005195 52.0
HKD3_k127_2594703_0 Aldehyde dehydrogenase K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 2.069e-194 620.0
HKD3_k127_2594703_1 Belongs to the GcvT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 602.0
HKD3_k127_2594703_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 546.0
HKD3_k127_2594703_3 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 412.0
HKD3_k127_2594703_4 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005517 284.0
HKD3_k127_2594703_5 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000000001367 156.0
HKD3_k127_2594703_6 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000415 154.0
HKD3_k127_2594703_7 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000004412 138.0
HKD3_k127_2594703_8 Mov34 MPN PAD-1 family K21140 - 3.13.1.6 0.000000000000000008775 96.0
HKD3_k127_2596855_0 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 366.0
HKD3_k127_2596855_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 344.0
HKD3_k127_2596855_2 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000093 289.0
HKD3_k127_2596855_3 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000987 144.0
HKD3_k127_2602629_0 Protein of unknown function (DUF2867) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 522.0
HKD3_k127_2602629_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000009122 216.0
HKD3_k127_2602629_2 Voltage gated chloride channel - - - 0.000000000000000000000000000000000000000000000000000000001961 220.0
HKD3_k127_2602629_3 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000007987 166.0
HKD3_k127_2602629_4 DegV family - - - 0.0000000000000000000000000000000000002208 156.0
HKD3_k127_2602629_5 - - - - 0.000000000000000000000000000000002344 143.0
HKD3_k127_2602629_6 - - - - 0.00000000007831 69.0
HKD3_k127_2602629_7 - - - - 0.000000006527 60.0
HKD3_k127_2607706_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000001922 181.0
HKD3_k127_2607706_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000002181 109.0
HKD3_k127_2607706_2 Binds to the 23S rRNA K02939 - - 0.00000000000000000000001574 112.0
HKD3_k127_2607706_3 Protein of unknown function (DUF1232) - - - 0.0001053 53.0
HKD3_k127_2609154_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 409.0
HKD3_k127_2618558_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000004188 245.0
HKD3_k127_2618558_1 SMART HNH nuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000417 218.0
HKD3_k127_2618558_2 Biotin carboxylase C-terminal domain K01959,K01965,K01968 - 6.4.1.1,6.4.1.3,6.4.1.4 0.00000000000001051 79.0
HKD3_k127_2619718_0 PFAM TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 379.0
HKD3_k127_2624685_0 - - - - 0.00000000000000000000000000000000009205 151.0
HKD3_k127_2624685_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000128 149.0
HKD3_k127_2624685_2 Major facilitator superfamily - - - 0.000000002967 69.0
HKD3_k127_2624685_3 AI-2E family transporter - - - 0.000000007512 61.0
HKD3_k127_2630586_0 bifunctional deaminase-reductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 345.0
HKD3_k127_2630586_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000004388 106.0
HKD3_k127_2630586_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000002452 55.0
HKD3_k127_2632221_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01761 - 2.5.1.48,4.4.1.11 0.000000000000000000000000000000000000000000000000000000002411 207.0
HKD3_k127_2632221_1 AsnC family K03718 - - 0.000000000000000000000000000000000000000000000001742 178.0
HKD3_k127_2632221_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000003792 161.0
HKD3_k127_2632221_3 Glycosyl transferases group 1 K16150 - 2.4.1.11 0.00000000000000000000000000000000000001249 165.0
HKD3_k127_2649394_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000006439 170.0
HKD3_k127_2649394_1 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000001115 86.0
HKD3_k127_2649394_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000007161 76.0
HKD3_k127_2649394_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate - - - 0.000000008287 57.0
HKD3_k127_2653375_0 Glycosyl Transferase - - - 1.003e-251 797.0
HKD3_k127_2653375_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000003819 163.0
HKD3_k127_2653375_2 Glycosyl Transferase - - - 0.000000004619 57.0
HKD3_k127_2660145_0 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 331.0
HKD3_k127_2660145_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 296.0
HKD3_k127_2660145_2 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 286.0
HKD3_k127_2660145_3 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000001624 146.0
HKD3_k127_2691776_0 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 400.0
HKD3_k127_2691776_1 Nickel-dependent hydrogenase K06281 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 321.0
HKD3_k127_2691776_2 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000005461 162.0
HKD3_k127_2693871_0 Aldehyde dehydrogenase family K04021,K13922 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009909 473.0
HKD3_k127_2693871_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 458.0
HKD3_k127_2693871_10 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000899 216.0
HKD3_k127_2693871_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000002243 205.0
HKD3_k127_2693871_12 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000000003177 191.0
HKD3_k127_2693871_13 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000002632 181.0
HKD3_k127_2693871_14 ABC-type Na efflux pump, permease component K01992 - - 0.00000000000000000000000000000000000000001596 169.0
HKD3_k127_2693871_15 BMC K04027 - - 0.00000000000000000000000000000000002438 141.0
HKD3_k127_2693871_16 EamA-like transporter family - - - 0.000000000000000000000000000001054 137.0
HKD3_k127_2693871_17 Ethanolamine utilisation protein EutN/carboxysome - - - 0.000000000000000000000000000006604 121.0
HKD3_k127_2693871_18 propanediol utilization protein - - - 0.00000000000000000000000008279 120.0
HKD3_k127_2693871_19 PFAM ATP dependent DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000009593 113.0
HKD3_k127_2693871_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 425.0
HKD3_k127_2693871_20 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000002042 95.0
HKD3_k127_2693871_21 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000007072 76.0
HKD3_k127_2693871_22 Protein of unknown function (DUF971) - - - 0.000000003767 59.0
HKD3_k127_2693871_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 400.0
HKD3_k127_2693871_4 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 379.0
HKD3_k127_2693871_5 Exporter of polyketide antibiotics K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 385.0
HKD3_k127_2693871_6 PFAM BMC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007366 300.0
HKD3_k127_2693871_7 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000434 264.0
HKD3_k127_2693871_8 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001536 248.0
HKD3_k127_2693871_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000001929 244.0
HKD3_k127_2711357_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006148 263.0
HKD3_k127_2711357_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000001534 280.0
HKD3_k127_2711357_2 - - - - 0.000000000000000000000000000001792 124.0
HKD3_k127_2711357_3 YbaB/EbfC DNA-binding family K09747 - - 0.0000000000000000000000001763 118.0
HKD3_k127_2711357_4 - - - - 0.00005644 45.0
HKD3_k127_2715570_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 553.0
HKD3_k127_2715570_1 DinB family K18843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 322.0
HKD3_k127_2715570_2 KduI/IolB family K03337 - 5.3.1.30 0.000000000000000000000000000000000000000000000000001336 187.0
HKD3_k127_2715570_3 Psort location Cytoplasmic, score K00945 - 2.7.4.25 0.00000000000000000000000000003788 125.0
HKD3_k127_2722317_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 410.0
HKD3_k127_2722317_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 401.0
HKD3_k127_2722317_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 364.0
HKD3_k127_2722317_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 313.0
HKD3_k127_2722317_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000001283 217.0
HKD3_k127_2722317_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000006646 154.0
HKD3_k127_2740560_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0030312,GO:0044464,GO:0050896,GO:0055114,GO:0071944 1.2.7.11,1.2.7.3 4.098e-252 791.0
HKD3_k127_2740560_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.857e-229 760.0
HKD3_k127_2740560_10 Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000000000000000000000000000000000001643 167.0
HKD3_k127_2740560_11 AdoMet dependent proline di-methyltransferase - - - 0.00000000000000000000000000000000049 142.0
HKD3_k127_2740560_12 4Fe-4S binding domain - - - 0.00000000000000000000000000003213 120.0
HKD3_k127_2740560_13 GAF domain - - - 0.00000000000000000000004846 114.0
HKD3_k127_2740560_14 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.0000000000000000000001463 115.0
HKD3_k127_2740560_15 PFAM CBS domain containing protein - - - 0.0000000000000000004199 95.0
HKD3_k127_2740560_16 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000002185 92.0
HKD3_k127_2740560_17 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000005202 81.0
HKD3_k127_2740560_18 Family of unknown function (DUF5317) - - - 0.000000000001136 76.0
HKD3_k127_2740560_19 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000004619 57.0
HKD3_k127_2740560_2 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 481.0
HKD3_k127_2740560_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 454.0
HKD3_k127_2740560_4 Creatinase/Prolidase N-terminal domain K01271,K01274 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 353.0
HKD3_k127_2740560_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 289.0
HKD3_k127_2740560_6 PFAM Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002743 287.0
HKD3_k127_2740560_7 Belongs to the peptidase S8 family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001998 259.0
HKD3_k127_2740560_8 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000001111 236.0
HKD3_k127_2740560_9 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000001452 191.0
HKD3_k127_2790861_0 von Willebrand factor (vWF) type A domain - - - 1.354e-195 640.0
HKD3_k127_2790861_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 608.0
HKD3_k127_2792189_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 500.0
HKD3_k127_2804213_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 498.0
HKD3_k127_2804213_1 Calcineurin-like phosphoesterase K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 339.0
HKD3_k127_2804213_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002053 258.0
HKD3_k127_2804213_3 Sulfate transporter K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000001693 239.0
HKD3_k127_2804213_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000001198 201.0
HKD3_k127_2829624_0 Aromatic amino acid lyase K01745 - 4.3.1.3 1.505e-219 687.0
HKD3_k127_2829624_1 META domain - - - 0.0000000000000000000000000000002336 142.0
HKD3_k127_2829624_2 SpoIIAA-like - - - 0.000000000000000006565 88.0
HKD3_k127_2836362_0 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 493.0
HKD3_k127_2836362_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 458.0
HKD3_k127_2836362_10 Protein of unknown function (DUF4242) - - - 0.0000000000000000000000000000000000000011 150.0
HKD3_k127_2836362_11 Protein of unknown function (DUF3037) - - - 0.00000000000000000000000000000000000006379 151.0
HKD3_k127_2836362_12 - - - - 0.0000000000000000000000000003143 128.0
HKD3_k127_2836362_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000001226 85.0
HKD3_k127_2836362_14 Domain of unknown function (DUF4395) - - - 0.000000001037 65.0
HKD3_k127_2836362_15 Predicted permease K07089 - - 0.00002283 49.0
HKD3_k127_2836362_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 338.0
HKD3_k127_2836362_3 Serine threonine protein kinase involved in cell cycle control - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 310.0
HKD3_k127_2836362_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
HKD3_k127_2836362_5 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000256 271.0
HKD3_k127_2836362_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000002049 240.0
HKD3_k127_2836362_7 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000001686 214.0
HKD3_k127_2836362_8 His Kinase A (phosphoacceptor) domain K14982 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.0000000000000000000000000000000000000000000000003812 198.0
HKD3_k127_2836362_9 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000006046 190.0
HKD3_k127_2860788_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 448.0
HKD3_k127_2860788_1 NUDIX domain - - - 0.00000000000000000000000893 109.0
HKD3_k127_2869899_0 E1-E2 ATPase K01537,K12953 - 3.6.3.8 9.499e-296 949.0
HKD3_k127_2869899_1 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 415.0
HKD3_k127_2913712_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 359.0
HKD3_k127_2913712_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000002579 224.0
HKD3_k127_2913712_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000001119 140.0
HKD3_k127_2913712_3 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000003059 143.0
HKD3_k127_2913712_4 Ribosomal protein L30p/L7e K02907 - - 0.0000000000001134 74.0
HKD3_k127_2916296_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 554.0
HKD3_k127_2916296_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000013 243.0
HKD3_k127_2916296_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000003389 220.0
HKD3_k127_2941750_0 Deaminase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 361.0
HKD3_k127_2941750_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000287 280.0
HKD3_k127_2941750_2 S4 RNA-binding domain K04762 - - 0.00000000000000000000000000000003387 128.0
HKD3_k127_2941750_3 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000061 121.0
HKD3_k127_2941750_4 extracellular polysaccharide biosynthetic process K09690,K16554,K16692 - - 0.000002484 58.0
HKD3_k127_2976999_0 ggdef domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 439.0
HKD3_k127_2976999_1 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009774 290.0
HKD3_k127_2976999_2 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000006552 253.0
HKD3_k127_2976999_3 Bacterial signalling protein N terminal repeat - - - 0.0000000000000000000000000000000000000000000000000000000003625 223.0
HKD3_k127_2976999_4 membrane protein of uknown function UCP014873 - - - 0.0000000000000000000000000000000000000000000000000000003604 201.0
HKD3_k127_2976999_5 belongs to the sigma-70 factor family K03088 - - 0.000000000000000002303 86.0
HKD3_k127_2976999_6 ABC-2 family transporter protein - - - 0.0000000003967 63.0
HKD3_k127_2976999_7 - - - - 0.000000002589 62.0
HKD3_k127_2976999_8 - - - - 0.00004861 51.0
HKD3_k127_2979351_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 306.0
HKD3_k127_2979351_1 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009341 251.0
HKD3_k127_2979351_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000006342 124.0
HKD3_k127_2979351_3 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000002898 119.0
HKD3_k127_2979351_4 Cupin 2, conserved barrel domain protein K16953,K19547 - 4.4.1.3,5.3.3.19 0.000000000000000000000001344 116.0
HKD3_k127_2979351_5 - - - - 0.0000000001215 68.0
HKD3_k127_2979351_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000002759 55.0
HKD3_k127_298999_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 539.0
HKD3_k127_298999_1 Tryptophan/tyrosine permease family - - - 0.0000000000000000000000000000000000000000000000000000001331 205.0
HKD3_k127_298999_2 - - - - 0.0000000000000000000000000000002521 140.0
HKD3_k127_2992115_0 FAD dependent oxidoreductase central domain - - - 1.137e-218 688.0
HKD3_k127_2992115_1 nucleoside hydrolase K01239,K01250 - 3.2.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 358.0
HKD3_k127_2992115_10 PFAM NUDIX domain - - - 0.00000000000000000000000000000000002167 151.0
HKD3_k127_2992115_11 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.00000000000000000000000192 114.0
HKD3_k127_2992115_12 ECF sigma factor K03088 - - 0.000000000000000000000004461 109.0
HKD3_k127_2992115_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 317.0
HKD3_k127_2992115_3 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003342 263.0
HKD3_k127_2992115_4 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000004575 243.0
HKD3_k127_2992115_5 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000002351 209.0
HKD3_k127_2992115_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000009004 212.0
HKD3_k127_2992115_7 Electron transfer flavoprotein, beta subunit K03521 - - 0.00000000000000000000000000000000000000000000000000005466 211.0
HKD3_k127_2992115_8 phosphorelay sensor kinase activity K16923,K18967 - 2.7.7.65 0.00000000000000000000000000000000000000004121 165.0
HKD3_k127_2992115_9 Cobalt transport protein K02008,K16785 - - 0.0000000000000000000000000000000000007423 150.0
HKD3_k127_2996198_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01668 - 4.1.99.2 7.905e-266 826.0
HKD3_k127_2996198_1 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 546.0
HKD3_k127_2996198_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000003246 218.0
HKD3_k127_3014971_0 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000002099 116.0
HKD3_k127_3014971_1 displays overlapping activities with DnaJ, but functions under different conditions, probably acting as a molecular chaperone in an adaptive response to environmental stresses other than heat shock. Lacks autonomous chaperone activity K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.0000000000001155 80.0
HKD3_k127_3014971_2 AI-2E family transporter - - - 0.000000000001529 73.0
HKD3_k127_3048106_0 Anticodon-binding domain of tRNA K01870 - 6.1.1.5 0.0 1101.0
HKD3_k127_3048106_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 334.0
HKD3_k127_3048106_2 cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000000001018 214.0
HKD3_k127_3048106_3 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000004227 169.0
HKD3_k127_3048106_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000003505 115.0
HKD3_k127_3198509_0 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 413.0
HKD3_k127_3198509_1 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 372.0
HKD3_k127_3198509_2 triosephosphate isomerase K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000006883 213.0
HKD3_k127_3198509_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000009095 187.0
HKD3_k127_3198509_4 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000001136 138.0
HKD3_k127_3198509_5 HAD-superfamily hydrolase, subfamily IB, PSPase-like - - - 0.0000000000000000000000000193 119.0
HKD3_k127_325268_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 562.0
HKD3_k127_325268_1 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000002202 111.0
HKD3_k127_325268_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000005375 116.0
HKD3_k127_3317124_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 550.0
HKD3_k127_3317124_1 peptidase S9 prolyl oligopeptidase active site domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007463 368.0
HKD3_k127_3317124_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000164 167.0
HKD3_k127_3317124_3 acetyltransferase - - - 0.0000000000000000000002377 111.0
HKD3_k127_331809_0 Permease for cytosine/purines, uracil, thiamine, allantoin K03457 - - 1.307e-199 636.0
HKD3_k127_331809_1 Dihydropyrimidinase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004657 556.0
HKD3_k127_331809_2 Carbon-nitrogen hydrolase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 426.0
HKD3_k127_331809_3 Dihydroorotate dehydrogenase K17723 GO:0003674,GO:0003824,GO:0003954,GO:0006139,GO:0006206,GO:0006208,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016491,GO:0016651,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 1.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 379.0
HKD3_k127_331809_4 Cellulose biosynthesis protein BcsQ K02282 - - 0.00000000000000000000000000000000000000006365 169.0
HKD3_k127_331809_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000001669 149.0
HKD3_k127_331809_6 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963,K03111,K15125 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0019538,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001038 108.0
HKD3_k127_331809_7 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000002017 96.0
HKD3_k127_333520_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 501.0
HKD3_k127_333520_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000439 46.0
HKD3_k127_3336293_0 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000001505 203.0
HKD3_k127_3336293_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000002478 73.0
HKD3_k127_35074_0 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 409.0
HKD3_k127_35074_1 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000002428 216.0
HKD3_k127_35074_2 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000002787 189.0
HKD3_k127_35074_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 - - 0.0000000001991 64.0
HKD3_k127_35074_4 Serine carboxypeptidase - - - 0.000000713 53.0
HKD3_k127_35074_5 SnoaL-like domain - - - 0.00005735 51.0
HKD3_k127_356797_0 protein conserved in bacteria - - - 0.00000000000000000000000000000005625 133.0
HKD3_k127_356797_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000001409 123.0
HKD3_k127_356797_2 nUDIX hydrolase K01515,K03574,K03801,K08310 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008828,GO:0009058,GO:0009108,GO:0009110,GO:0009396,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017144,GO:0018130,GO:0019177,GO:0019438,GO:0019752,GO:0034641,GO:0042364,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0046656,GO:0046872,GO:0047429,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.181,3.6.1.13,3.6.1.55,3.6.1.67 0.00000498 59.0
HKD3_k127_3627739_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 438.0
HKD3_k127_3627739_1 Sulfate permease K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 379.0
HKD3_k127_3627739_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000009783 208.0
HKD3_k127_3627739_3 hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000002528 169.0
HKD3_k127_3645318_0 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 304.0
HKD3_k127_3645318_1 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000002713 217.0
HKD3_k127_3645318_2 Rieske-like [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000004512 205.0
HKD3_k127_3645318_3 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000001431 135.0
HKD3_k127_3645318_4 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000008836 134.0
HKD3_k127_3645318_5 nucleoside 2-deoxyribosyltransferase - - - 0.000000000000000000004267 103.0
HKD3_k127_3645318_6 - - - - 0.0000000000003817 80.0
HKD3_k127_3645318_7 Copper binding proteins, plastocyanin/azurin family - - - 0.000000003054 68.0
HKD3_k127_3645318_8 Anti-sigma K factor RskA - - - 0.000002903 59.0
HKD3_k127_3650141_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 604.0
HKD3_k127_3650141_1 Domain of unknown function (DUF1727) - - - 0.0000000000000000000000000000000000000000000000000000000000001133 233.0
HKD3_k127_3664438_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 585.0
HKD3_k127_3664438_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 295.0
HKD3_k127_3664438_2 CHAD - - - 0.0000000000000000000000000000000000000009283 165.0
HKD3_k127_3664438_3 CYTH - - - 0.00000002049 64.0
HKD3_k127_3664438_4 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0001746 48.0
HKD3_k127_3669418_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1291.0
HKD3_k127_3669418_1 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 369.0
HKD3_k127_3669418_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000006103 219.0
HKD3_k127_3669418_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000006154 229.0
HKD3_k127_3669418_4 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000001842 126.0
HKD3_k127_3669418_5 COG COG0210 Superfamily I DNA and RNA helicases DNA replication recombination and repair K03657 - 3.6.4.12 0.000000000000000000000000003928 124.0
HKD3_k127_3669418_6 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.000000000000000000000000005383 120.0
HKD3_k127_3669418_9 - - - - 0.00001654 53.0
HKD3_k127_3674616_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 1.353e-268 842.0
HKD3_k127_3674616_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 397.0
HKD3_k127_3674616_2 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 313.0
HKD3_k127_3674616_3 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000002641 230.0
HKD3_k127_3674616_4 Thioesterase superfamily - - - 0.00000000000000000000000002564 115.0
HKD3_k127_3674616_5 DNA alkylation repair enzyme - - - 0.00000005392 65.0
HKD3_k127_3675333_0 Enoyl-(Acyl carrier protein) reductase K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 319.0
HKD3_k127_3675333_1 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000012 192.0
HKD3_k127_3675333_2 Protein of unknown function (DUF429) - - - 0.00000000000000000000000000000000000000001679 163.0
HKD3_k127_3675333_3 YCII-related domain K09780 - - 0.0000000000000000000000000000000004375 133.0
HKD3_k127_3675333_4 -acetyltransferase - - - 0.00000000000003482 83.0
HKD3_k127_3675333_5 Nucleoside H+ symporter K05820 - - 0.0001523 54.0
HKD3_k127_3679148_0 Acyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001795 272.0
HKD3_k127_3679148_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000002871 235.0
HKD3_k127_3688508_0 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000407 145.0
HKD3_k127_3688508_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006457,GO:0006458,GO:0006725,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009295,GO:0009408,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016465,GO:0030312,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042026,GO:0042262,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043388,GO:0043590,GO:0044093,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0050896,GO:0051082,GO:0051098,GO:0051099,GO:0051101,GO:0051716,GO:0061077,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090143,GO:0090304,GO:0097159,GO:0101031,GO:1901360,GO:1901363,GO:1990220,GO:2000677,GO:2000679 - 0.00000000000008889 72.0
HKD3_k127_3688508_3 Mg-dependent DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.0005491 44.0
HKD3_k127_3688777_0 xylulokinase activity K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000008581 276.0
HKD3_k127_3688777_1 ABC transporter K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000001843 239.0
HKD3_k127_3688777_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000003112 59.0
HKD3_k127_3689666_0 Protein of unknown function (DUF1211) - - - 0.00000000000000000000000000000000000000000000000000000000000000001416 231.0
HKD3_k127_3689666_1 PFAM glycoside hydrolase family 25 - - - 0.00000000000000000000000000000000001479 150.0
HKD3_k127_3689666_2 transcriptional regulator, Rrf2 family - - - 0.000000000000000000004757 95.0
HKD3_k127_3733863_0 Bacterial-like globin K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 481.0
HKD3_k127_3733863_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 317.0
HKD3_k127_3733863_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008913 283.0
HKD3_k127_3733863_3 amine dehydrogenase activity K09815 - - 0.0000000000000000000000000000000000000000000008565 184.0
HKD3_k127_3733863_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001672 101.0
HKD3_k127_3744659_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 427.0
HKD3_k127_3744659_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 299.0
HKD3_k127_3744659_2 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006757 275.0
HKD3_k127_3744659_3 ArsC family - - - 0.00000000000000000111 87.0
HKD3_k127_3744659_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000004636 74.0
HKD3_k127_3744659_5 Rieske 2Fe-2S iron-sulphur domain K05710,K14750 - - 0.000000000006578 74.0
HKD3_k127_3744659_6 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820,K15916 - 2.6.1.16,5.3.1.8,5.3.1.9 0.000000002435 68.0
HKD3_k127_3760894_0 Cytochrome b/b6/petB K03891 - - 0.00000000000000000000000000000000000000000000000000000000001335 207.0
HKD3_k127_3760894_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.000000000000000000000000000000000000000001498 162.0
HKD3_k127_3760894_2 Rieske 2Fe-2S - - - 0.000000000000000000000000009988 119.0
HKD3_k127_3760894_3 conserved protein (DUF2203) - - - 0.0000000000000001401 87.0
HKD3_k127_3760894_4 PFAM blue (type 1) copper domain protein - - - 0.0000000000001318 83.0
HKD3_k127_3760894_5 - - - - 0.00001096 58.0
HKD3_k127_3760894_6 Domain of unknown function (DUF309) K09763 - - 0.0000235 53.0
HKD3_k127_3760894_7 TIGRFAM cytochrome c oxidase, cbb3-type, subunit III K00406 - - 0.0005305 52.0
HKD3_k127_3768652_0 E1-E2 ATPase K01537,K12953 - 3.6.3.8 0.0 1039.0
HKD3_k127_3768652_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 1.295e-195 618.0
HKD3_k127_3768652_2 belongs to the aldehyde dehydrogenase family K09472 - 1.2.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 609.0
HKD3_k127_3768652_3 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 428.0
HKD3_k127_3768652_4 Protein of unknown function (DUF4242) - - - 0.00000000000000000000004914 114.0
HKD3_k127_3768652_5 - - - - 0.00000000000001848 81.0
HKD3_k127_3769739_0 Glycosyl hydrolase family 1 K05350 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004773 436.0
HKD3_k127_3769739_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000213 194.0
HKD3_k127_3769739_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000000001738 166.0
HKD3_k127_3777307_0 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0 1603.0
HKD3_k127_3777307_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 590.0
HKD3_k127_3777307_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K01919,K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 346.0
HKD3_k127_3777307_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000003972 76.0
HKD3_k127_3778381_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 2.497e-295 937.0
HKD3_k127_3778381_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.261e-291 915.0
HKD3_k127_3778381_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 416.0
HKD3_k127_3778381_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 364.0
HKD3_k127_3778381_4 DUF218 domain - - - 0.000000000000000000000000000000000000000002871 170.0
HKD3_k127_3778381_5 DNA alkylation repair enzyme - - - 0.0000000005537 70.0
HKD3_k127_3778381_6 Acetyltransferase (GNAT) domain - - - 0.00009953 54.0
HKD3_k127_3780005_0 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000000000000000000003981 195.0
HKD3_k127_3780005_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000001412 154.0
HKD3_k127_3780005_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000003241 88.0
HKD3_k127_3780005_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0005154 48.0
HKD3_k127_3787935_0 PFAM VanW family protein - - - 0.000000000000000000000000000001663 139.0
HKD3_k127_3787935_1 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.0000000000000000000000000002232 133.0
HKD3_k127_3787935_2 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000000000001293 118.0
HKD3_k127_3787935_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000002344 98.0
HKD3_k127_3787935_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000003322 78.0
HKD3_k127_3787935_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000002068 67.0
HKD3_k127_3810260_0 RimK-like ATP-grasp domain K03802 - 6.3.2.29,6.3.2.30 0.0 1150.0
HKD3_k127_3810260_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004265 540.0
HKD3_k127_3810260_10 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004862 310.0
HKD3_k127_3810260_11 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000006022 271.0
HKD3_k127_3810260_12 DRTGG domain K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005177 252.0
HKD3_k127_3810260_13 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000008118 193.0
HKD3_k127_3810260_14 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000001476 194.0
HKD3_k127_3810260_15 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000004609 195.0
HKD3_k127_3810260_16 DegV family - - - 0.00000000000000000000000000000000000000000000347 177.0
HKD3_k127_3810260_17 L-valine transmembrane transporter activity - - - 0.00000000000000000000000000000001882 140.0
HKD3_k127_3810260_18 Glycogen debranching enzyme - - - 0.00000000253 70.0
HKD3_k127_3810260_19 - - - - 0.0000009415 57.0
HKD3_k127_3810260_2 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006863,GO:0008150,GO:0015205,GO:0015208,GO:0015851,GO:0015854,GO:0016020,GO:0022857,GO:0035344,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098657,GO:0098710,GO:0098739,GO:1903716,GO:1904823 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 426.0
HKD3_k127_3810260_20 Glycosyltransferase family 87 - - - 0.00003974 55.0
HKD3_k127_3810260_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 405.0
HKD3_k127_3810260_4 PFAM Adenosine AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 388.0
HKD3_k127_3810260_5 Mur ligase middle domain K03802 - 6.3.2.29,6.3.2.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 338.0
HKD3_k127_3810260_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 346.0
HKD3_k127_3810260_7 peptidase K01295 - 3.4.17.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008058 332.0
HKD3_k127_3810260_8 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 319.0
HKD3_k127_3810260_9 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002233 309.0
HKD3_k127_3811495_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 1.77e-260 846.0
HKD3_k127_3811495_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058,K16843 - 1.1.1.310,1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 471.0
HKD3_k127_3811495_10 lipopolysaccharide transmembrane transporter activity K07058 - - 0.000001141 60.0
HKD3_k127_3811495_2 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 454.0
HKD3_k127_3811495_3 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 430.0
HKD3_k127_3811495_4 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000005031 228.0
HKD3_k127_3811495_5 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000004665 189.0
HKD3_k127_3811495_6 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000000000000000000000000000000002997 139.0
HKD3_k127_3811495_7 Belongs to the phosphoglycerate mutase family - - - 0.000000000000000000001204 106.0
HKD3_k127_3811495_8 Protein of unknown function (DUF4446) - - - 0.00000000000000000001478 100.0
HKD3_k127_3811495_9 Regulatory protein, FmdB family - - - 0.00000001143 61.0
HKD3_k127_382595_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000001258 204.0
HKD3_k127_382595_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000004319 184.0
HKD3_k127_382595_2 Stage II sporulation protein K06381 - - 0.000000000000000000000000000004597 128.0
HKD3_k127_382595_3 membrane - - - 0.00000001357 65.0
HKD3_k127_383091_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 321.0
HKD3_k127_383091_1 COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000008784 228.0
HKD3_k127_383091_2 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000002224 63.0
HKD3_k127_383525_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1189.0
HKD3_k127_383525_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 630.0
HKD3_k127_383525_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 425.0
HKD3_k127_383525_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 410.0
HKD3_k127_383525_4 ABC-type molybdenum transport system, ATPase component photorepair protein PhrA K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001863 275.0
HKD3_k127_383525_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000008937 163.0
HKD3_k127_383525_6 nadp oxidoreductase, coenzyme f420-dependent - - - 0.0000000000000000000000000000000000000000315 167.0
HKD3_k127_383525_7 NUDIX domain - - - 0.000000000000000000000000000000004028 134.0
HKD3_k127_3837343_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 404.0
HKD3_k127_3837343_1 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 314.0
HKD3_k127_3837343_10 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.0003254 54.0
HKD3_k127_3837343_2 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003687 280.0
HKD3_k127_3837343_3 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000001934 250.0
HKD3_k127_3837343_4 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000001256 183.0
HKD3_k127_3837343_5 Response regulator receiver K07696 - - 0.0000000000000000000000000000006914 133.0
HKD3_k127_3837343_6 - - - - 0.000000000000006076 80.0
HKD3_k127_3837343_7 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000007934 84.0
HKD3_k127_3837343_8 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K11206 - - 0.000000000433 72.0
HKD3_k127_3837343_9 SnoaL-like polyketide cyclase K06893 - - 0.00001535 53.0
HKD3_k127_3846316_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 599.0
HKD3_k127_3859456_0 Carbamoyl-phosphate synthase K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 5.823e-282 921.0
HKD3_k127_3859456_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 445.0
HKD3_k127_3859456_10 pyrroloquinoline quinone binding - - - 0.000000000000000000000000187 124.0
HKD3_k127_3859456_11 MFS/sugar transport protein - - - 0.000003191 59.0
HKD3_k127_3859456_12 - - - - 0.00001395 55.0
HKD3_k127_3859456_2 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 435.0
HKD3_k127_3859456_3 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 405.0
HKD3_k127_3859456_4 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 394.0
HKD3_k127_3859456_5 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 346.0
HKD3_k127_3859456_6 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 339.0
HKD3_k127_3859456_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000106 238.0
HKD3_k127_3859456_8 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000909 214.0
HKD3_k127_3859456_9 binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription this protein is involved in detoxification and protection against antimicrobial K03088 - - 0.0000000000000000000000001148 116.0
HKD3_k127_3873223_0 Predicted membrane protein (DUF2254) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 375.0
HKD3_k127_3873223_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000007041 233.0
HKD3_k127_3873223_10 Domain of unknown function (DUF4332) - - - 0.0000000000000000000000000000004943 136.0
HKD3_k127_3873223_11 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000008178 119.0
HKD3_k127_3873223_12 Phospholipid methyltransferase - - - 0.000000000001004 77.0
HKD3_k127_3873223_13 PFAM LysM domain - - - 0.00001321 56.0
HKD3_k127_3873223_14 - - - - 0.0004062 51.0
HKD3_k127_3873223_2 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001298 224.0
HKD3_k127_3873223_3 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000008751 231.0
HKD3_k127_3873223_4 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.00000000000000000000000000000000000000000000000000000007375 217.0
HKD3_k127_3873223_5 Sulfate transporter K03321 - - 0.00000000000000000000000000000000000000000000000000002223 199.0
HKD3_k127_3873223_6 TIGRFAM molybdenum ABC transporter, periplasmic K02020 - - 0.0000000000000000000000000000000000000000002333 169.0
HKD3_k127_3873223_7 - - - - 0.0000000000000000000000000000000000000001209 160.0
HKD3_k127_3873223_8 ACT domain - - - 0.000000000000000000000000000000000000003317 156.0
HKD3_k127_3873223_9 DNA binding domain - - - 0.0000000000000000000000000000001678 130.0
HKD3_k127_3883078_0 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009928 354.0
HKD3_k127_3883078_1 ROK family K00845,K00886 - 2.7.1.2,2.7.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000006345 267.0
HKD3_k127_3887177_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 517.0
HKD3_k127_3887177_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 468.0
HKD3_k127_3887177_2 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002912 463.0
HKD3_k127_3887177_3 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 376.0
HKD3_k127_3887177_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000002651 153.0
HKD3_k127_3887177_5 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000006403 132.0
HKD3_k127_3887177_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000002536 138.0
HKD3_k127_3901889_0 membrane protein of uknown function UCP014873 - - - 0.0000000000000000000000000002409 120.0
HKD3_k127_3901889_1 Short C-terminal domain - - - 0.0000000000000162 80.0
HKD3_k127_3901889_2 Voltage gated chloride channel - - - 0.0000004238 58.0
HKD3_k127_3912198_0 DegT/DnrJ/EryC1/StrS aminotransferase family K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 458.0
HKD3_k127_3912198_1 PFAM Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000000000000000000003361 211.0
HKD3_k127_3912198_2 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000001903 182.0
HKD3_k127_3912198_3 diguanylate cyclase - - - 0.00000121 61.0
HKD3_k127_391722_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.223e-236 752.0
HKD3_k127_391722_1 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 383.0
HKD3_k127_391722_10 - - - - 0.00000007087 61.0
HKD3_k127_391722_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 317.0
HKD3_k127_391722_3 COGs COG3367 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 315.0
HKD3_k127_391722_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000001315 253.0
HKD3_k127_391722_5 conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000001156 231.0
HKD3_k127_391722_6 N-4 methylation of cytosine K00590 - 2.1.1.113 0.0000000000000000000000000000000000000000000000000000001588 212.0
HKD3_k127_391722_7 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000006629 168.0
HKD3_k127_391722_8 PFAM regulatory protein, ArsR - - - 0.000000000000000000000000000000000001018 150.0
HKD3_k127_391722_9 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000003073 107.0
HKD3_k127_3923412_0 Lecithin:cholesterol acyltransferase - - - 0.000000000000000000000000000000000000000007984 162.0
HKD3_k127_3923412_1 Protein of unknown function (DUF642) - - - 0.0000000000000000000000000001965 128.0
HKD3_k127_3923412_2 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000011 59.0
HKD3_k127_392747_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 7.572e-253 811.0
HKD3_k127_392747_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000001798 71.0
HKD3_k127_392747_2 SAF K02279 - - 0.0000000001076 73.0
HKD3_k127_3936450_0 fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001593 255.0
HKD3_k127_3936450_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000006159 235.0
HKD3_k127_3936450_2 Fibronectin type 3 domain K06882 - - 0.00000000000000001162 91.0
HKD3_k127_3946376_0 Major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 357.0
HKD3_k127_3946376_1 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 295.0
HKD3_k127_3946376_10 Amino acid permease - - - 0.0000000147 63.0
HKD3_k127_3946376_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000591 278.0
HKD3_k127_3946376_3 PFAM photosystem I assembly BtpA K06971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007797 275.0
HKD3_k127_3946376_4 amino acid - - - 0.0000000000000000000000000000000000000000000000000000002682 218.0
HKD3_k127_3946376_5 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000001522 217.0
HKD3_k127_3946376_6 - - - - 0.0000000000000000000000000000000000000000000000002592 190.0
HKD3_k127_3946376_7 DeoR C terminal sensor domain K02081,K03436 - - 0.000000000000000000000000000000000000003706 156.0
HKD3_k127_3946376_8 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00000000000000000000001942 107.0
HKD3_k127_3946376_9 - K03649 - 3.2.2.28 0.0000000000002298 79.0
HKD3_k127_3953189_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 5.216e-284 884.0
HKD3_k127_3953189_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.718e-207 661.0
HKD3_k127_3971579_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 432.0
HKD3_k127_3971579_1 Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms K14205 - 2.3.2.3 0.0000000000000000000000000000000000008434 159.0
HKD3_k127_3971579_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 GO:0000162,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000005438 158.0
HKD3_k127_3971579_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000002874 107.0
HKD3_k127_3971579_4 esterase - - - 0.000000000000000000000008874 116.0
HKD3_k127_3977299_0 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 383.0
HKD3_k127_3986605_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000007625 96.0
HKD3_k127_3986605_1 PFAM Chlorite dismutase - - - 0.00000000000000001225 87.0
HKD3_k127_4010701_0 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1220.0
HKD3_k127_4010701_1 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001669 271.0
HKD3_k127_4010701_2 YHS domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002557 271.0
HKD3_k127_4010701_3 COGs COG2080 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS CutS homologs K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000002643 239.0
HKD3_k127_4010701_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000003102 248.0
HKD3_k127_4010701_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000564 165.0
HKD3_k127_4010701_6 oxidoreductase activity, acting on CH-OH group of donors K09386 - - 0.000000000000000000000000000000000000002986 151.0
HKD3_k127_4010701_7 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000003237 134.0
HKD3_k127_4010701_8 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K07003 - - 0.00000000000000000000000001134 122.0
HKD3_k127_401847_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 1.924e-204 646.0
HKD3_k127_401847_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 520.0
HKD3_k127_401847_10 FMN binding - - - 0.000000000000000000000000001557 119.0
HKD3_k127_401847_11 integral membrane protein K00728 - 2.4.1.109 0.00000000000000000000000006583 115.0
HKD3_k127_401847_12 Ferric reductase like transmembrane component - - - 0.0000000000000000000000002992 123.0
HKD3_k127_401847_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 505.0
HKD3_k127_401847_3 GtrA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 450.0
HKD3_k127_401847_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 445.0
HKD3_k127_401847_5 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07665 - - 0.0000000000000000000000000000000000000000000000000005266 191.0
HKD3_k127_401847_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000009118 146.0
HKD3_k127_401847_7 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000002284 133.0
HKD3_k127_401847_8 Peptidase S16, lon domain protein K01338,K07157 - 3.4.21.53 0.000000000000000000000000000000003292 139.0
HKD3_k127_401847_9 protein histidine kinase activity - - - 0.00000000000000000000000000000001199 145.0
HKD3_k127_4033890_0 Voltage gated chloride channel K03281 - - 4.324e-195 634.0
HKD3_k127_4033890_1 Di-haem cytochrome c peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 518.0
HKD3_k127_4033890_2 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002576 246.0
HKD3_k127_4033890_3 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000002725 179.0
HKD3_k127_4033890_4 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000624 169.0
HKD3_k127_4033890_5 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000002007 151.0
HKD3_k127_4033890_6 Cold shock K03704 - - 0.0000000002066 65.0
HKD3_k127_4033890_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00002518 55.0
HKD3_k127_4035423_0 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000001137 155.0
HKD3_k127_4055480_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 593.0
HKD3_k127_4055480_1 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 493.0
HKD3_k127_4055480_10 Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000005088 128.0
HKD3_k127_4055480_11 ABC-2 family transporter protein K01992 - - 0.00000000000007004 85.0
HKD3_k127_4055480_12 Phospholipase_D-nuclease N-terminal - - - 0.0000002041 63.0
HKD3_k127_4055480_2 COG1172 Ribose xylose arabinose galactoside ABC-type transport systems, permease components K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 353.0
HKD3_k127_4055480_3 COG1129 ABC-type sugar transport system, ATPase component K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 360.0
HKD3_k127_4055480_4 Periplasmic binding protein domain K02058,K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 329.0
HKD3_k127_4055480_5 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 309.0
HKD3_k127_4055480_6 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002813 275.0
HKD3_k127_4055480_7 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002382 254.0
HKD3_k127_4055480_8 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001212 240.0
HKD3_k127_4055480_9 TIGRFAM LPXTG-motif cell wall anchor domain - - - 0.0000000000000000000000000000000000000000001821 171.0
HKD3_k127_4058113_0 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 463.0
HKD3_k127_4058113_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000002333 112.0
HKD3_k127_4058113_2 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin - - - 0.000005273 59.0
HKD3_k127_4065043_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0030312,GO:0044237,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 624.0
HKD3_k127_4065043_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 483.0
HKD3_k127_4065043_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 420.0
HKD3_k127_4065043_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 377.0
HKD3_k127_4065043_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004213 274.0
HKD3_k127_4065043_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000007938 175.0
HKD3_k127_4065043_6 Histidine biosynthesis protein K01814 - 5.3.1.16 0.00000000000000000000000000000000003031 142.0
HKD3_k127_4065043_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000137 141.0
HKD3_k127_4065043_8 Modulates RecA activity K03565 - - 0.0000000000000004251 85.0
HKD3_k127_4074872_0 MazG nucleotide pyrophosphohydrolase domain K02428,K02499 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66 0.0000000000000000000000000000000000000002075 164.0
HKD3_k127_4074872_1 glycosyl transferase - - - 0.00000000000000006481 90.0
HKD3_k127_4074872_2 positive regulation of chromatin silencing at rDNA K02887,K09578 GO:0000122,GO:0000413,GO:0000993,GO:0001098,GO:0001099,GO:0001817,GO:0001818,GO:0001932,GO:0001933,GO:0001934,GO:0003674,GO:0003755,GO:0003774,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006325,GO:0006351,GO:0006353,GO:0006355,GO:0006357,GO:0006366,GO:0006369,GO:0006396,GO:0006397,GO:0006457,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0007088,GO:0007275,GO:0007346,GO:0007399,GO:0008013,GO:0008150,GO:0008152,GO:0008213,GO:0009058,GO:0009059,GO:0009405,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009966,GO:0009967,GO:0009968,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010562,GO:0010563,GO:0010564,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0010648,GO:0016043,GO:0016070,GO:0016071,GO:0016462,GO:0016569,GO:0016570,GO:0016571,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016859,GO:0017015,GO:0017111,GO:0018022,GO:0018023,GO:0018130,GO:0018193,GO:0018205,GO:0018208,GO:0018995,GO:0019219,GO:0019220,GO:0019222,GO:0019438,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0023051,GO:0023056,GO:0023057,GO:0030111,GO:0030154,GO:0030162,GO:0030177,GO:0030182,GO:0030430,GO:0030496,GO:0030512,GO:0031056,GO:0031057,GO:0031063,GO:0031064,GO:0031123,GO:0031124,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031329,GO:0031330,GO:0031334,GO:0031396,GO:0031398,GO:0031399,GO:0031400,GO:0031401,GO:0031434,GO:0031647,GO:0031935,GO:0031937,GO:0031974,GO:0031981,GO:0032091,GO:0032092,GO:0032259,GO:0032268,GO:0032269,GO:0032270,GO:0032465,GO:0032479,GO:0032480,GO:0032501,GO:0032502,GO:0032774,GO:0032784,GO:0032794,GO:0032879,GO:0032880,GO:0033043,GO:0033044,GO:0033643,GO:0033646,GO:0033647,GO:0033648,GO:0034243,GO:0034641,GO:0034645,GO:0034654,GO:0034968,GO:0035303,GO:0035304,GO:0035306,GO:0035307,GO:0035821,GO:0036211,GO:0040012,GO:0040013,GO:0042025,GO:0042176,GO:0042177,GO:0042325,GO:0042326,GO:0042327,GO:0043085,GO:0043087,GO:0043170,GO:0043175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043254,GO:0043393,GO:0043408,GO:0043409,GO:0043412,GO:0043414,GO:0043547,GO:0043656,GO:0043657,GO:0044003,GO:0044087,GO:0044089,GO:0044092,GO:0044093,GO:0044215,GO:0044216,GO:0044217,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0045309,GO:0045861,GO:0045892,GO:0045893,GO:0045898,GO:0045899,GO:0045934,GO:0045935,GO:0045936,GO:0045937,GO:0045944,GO:0046483,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050789,GO:0050790,GO:0050794,GO:0050808,GO:0050815,GO:0050816,GO:0050821,GO:0051098,GO:0051099,GO:0051100,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051174,GO:0051219,GO:0051239,GO:0051241,GO:0051246,GO:0051247,GO:0051248,GO:0051252,GO:0051253,GO:0051254,GO:0051270,GO:0051271,GO:0051276,GO:0051302,GO:0051336,GO:0051338,GO:0051345,GO:0051347,GO:0051438,GO:0051443,GO:0051568,GO:0051701,GO:0051704,GO:0051726,GO:0051783,GO:0051817,GO:0060255,GO:0060260,GO:0060261,GO:0060341,GO:0060393,GO:0060828,GO:0060968,GO:0061187,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070063,GO:0070372,GO:0070373,GO:0071704,GO:0071840,GO:0080090,GO:0080182,GO:0090092,GO:0090101,GO:0090263,GO:0090287,GO:0090288,GO:0090304,GO:0090311,GO:0097659,GO:0140096,GO:1900180,GO:1901360,GO:1901362,GO:1901407,GO:1901564,GO:1901576,GO:1901796,GO:1902275,GO:1902531,GO:1902532,GO:1902679,GO:1902680,GO:1903050,GO:1903051,GO:1903320,GO:1903322,GO:1903362,GO:1903363,GO:1903506,GO:1903507,GO:1903508,GO:1903827,GO:1903844,GO:1903845,GO:1905268,GO:1905269,GO:2000058,GO:2000059,GO:2000112,GO:2000113,GO:2000142,GO:2000144,GO:2000145,GO:2000146,GO:2000749,GO:2001141,GO:2001251,GO:2001252 5.2.1.8 0.000000000000702 82.0
HKD3_k127_4074872_3 SurA N-terminal domain - - - 0.000000006748 69.0
HKD3_k127_41102_0 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 369.0
HKD3_k127_41102_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000003347 192.0
HKD3_k127_41102_2 Diguanylate cyclase - - - 0.00000000000000000000000000000002209 142.0
HKD3_k127_41102_3 PHP domain K02347 - - 0.000000000000101 78.0
HKD3_k127_41102_4 PFAM natural resistance-associated macrophage protein - - - 0.00000000000227 70.0
HKD3_k127_4120085_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 376.0
HKD3_k127_4120085_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.00000000000000000000000000000000000000000000000000000002373 201.0
HKD3_k127_4139643_0 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000001799 199.0
HKD3_k127_4139643_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000008163 207.0
HKD3_k127_4139643_2 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.0000000000000000000000000000000000001348 153.0
HKD3_k127_4139643_3 YbaK prolyl-tRNA synthetase associated region - - - 0.0000000000000000000000000000002239 131.0
HKD3_k127_4139643_4 glycolate biosynthetic process K01091,K06019,K13292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008967,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.1.3.18,3.6.1.1 0.0000000000000000000000000004199 130.0
HKD3_k127_4171975_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 3.044e-272 847.0
HKD3_k127_4171975_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000506 264.0
HKD3_k127_4188763_0 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 387.0
HKD3_k127_4188763_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 342.0
HKD3_k127_4188763_10 Dipeptidyl peptidase IV (DPP IV) N-terminal region K03641 - - 0.0000000000000000138 96.0
HKD3_k127_4188763_11 protein secretion K03116,K03117,K03646 - - 0.00000000000009532 84.0
HKD3_k127_4188763_12 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000004317 61.0
HKD3_k127_4188763_2 Single-strand DNA-specific exonuclease, C terminal domain K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 323.0
HKD3_k127_4188763_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003738 263.0
HKD3_k127_4188763_4 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000003538 214.0
HKD3_k127_4188763_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000004218 213.0
HKD3_k127_4188763_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000009924 201.0
HKD3_k127_4188763_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000327 178.0
HKD3_k127_4188763_8 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000007259 170.0
HKD3_k127_4188763_9 May be required for sporulation K09762 - - 0.0000000000000000000007363 106.0
HKD3_k127_4194600_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00122,K00335 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 463.0
HKD3_k127_4194600_1 2Fe-2S iron-sulfur cluster binding domain K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 422.0
HKD3_k127_4194600_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000004899 114.0
HKD3_k127_4198545_0 Aldo/keto reductase family K19265 GO:0003674,GO:0003824,GO:0006081,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0033554,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0050896,GO:0051596,GO:0051716,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 535.0
HKD3_k127_4198545_1 PFAM Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 432.0
HKD3_k127_4198545_2 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007533 282.0
HKD3_k127_4198545_3 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000001003 213.0
HKD3_k127_4198545_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000001547 201.0
HKD3_k127_4198545_5 Arylsulfotransferase (ASST) - - - 0.000000000000002593 79.0
HKD3_k127_4198545_6 - - - - 0.000000000004981 74.0
HKD3_k127_4212325_0 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 479.0
HKD3_k127_4212325_1 esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000003232 248.0
HKD3_k127_4307668_0 Part of the ABC transporter complex DrrAB involved in daunorubicin and doxorubicin resistance. Responsible for energy coupling to the transport system. Binds ATP or GTP K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 412.0
HKD3_k127_4307668_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
HKD3_k127_4307668_2 - - - - 0.000000000000000000000000000000000000000000000000008798 186.0
HKD3_k127_4307668_3 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000006975 117.0
HKD3_k127_4354691_0 ATP dependent DNA ligase C terminal region K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 465.0
HKD3_k127_4354691_1 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000008305 212.0
HKD3_k127_4354691_2 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000008745 138.0
HKD3_k127_4354691_3 Cys/Met metabolism PLP-dependent enzyme K11325 - - 0.0000000000000003441 82.0
HKD3_k127_4467298_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0016021,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0034220,GO:0040007,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 2.07e-202 644.0
HKD3_k127_4467298_1 Belongs to the ABC transporter superfamily K02052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 473.0
HKD3_k127_4467298_10 Cytochrome c oxidase subunit K02275 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006119,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009319,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016310,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0034641,GO:0040007,GO:0042773,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044237,GO:0044238,GO:0044281,GO:0044403,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0051704,GO:0055086,GO:0055114,GO:0070069,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.9.3.1 0.00000000000000000000000000000000000002107 161.0
HKD3_k127_4467298_11 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.00000000000000000000000000001659 124.0
HKD3_k127_4467298_12 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000001999 131.0
HKD3_k127_4467298_13 Sugar (and other) transporter - - - 0.0000000000000000000000002622 120.0
HKD3_k127_4467298_14 Aminotransferase class-V K04127 - 5.1.1.17 0.0000000000000008029 79.0
HKD3_k127_4467298_15 Transcriptional regulator, TraR DksA family K06204 - - 0.0000000000002245 74.0
HKD3_k127_4467298_16 PFAM blue (type 1) copper domain protein - - - 0.00000000001164 76.0
HKD3_k127_4467298_17 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.00000001794 65.0
HKD3_k127_4467298_18 Copper binding proteins, plastocyanin/azurin family - - - 0.00000002623 64.0
HKD3_k127_4467298_2 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 436.0
HKD3_k127_4467298_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 342.0
HKD3_k127_4467298_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 323.0
HKD3_k127_4467298_5 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 321.0
HKD3_k127_4467298_6 PFAM binding-protein-dependent transport systems inner membrane component K02053 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000535 297.0
HKD3_k127_4467298_7 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001911 266.0
HKD3_k127_4467298_8 Cytochrome c oxidase K02351,K07245 - - 0.00000000000000000000000000000000000000000000000002334 193.0
HKD3_k127_4467298_9 PFAM cytochrome c oxidase subunit III K02276,K02299 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 1.9.3.1 0.00000000000000000000000000000000000000018 161.0
HKD3_k127_451153_0 PFAM NMT1 THI5 like domain protein K02051 - - 0.0000000000000000000000000000000000000000000000001213 196.0
HKD3_k127_451153_1 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000008281 125.0
HKD3_k127_4557246_0 - - - - 0.0000000000000000000000000000000000000001886 152.0
HKD3_k127_4642468_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 397.0
HKD3_k127_4642468_1 Winged helix DNA-binding domain - - - 0.00000000000000000236 89.0
HKD3_k127_4642468_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000009322 76.0
HKD3_k127_4757429_0 COG0659 Sulfate permease and related transporters (MFS superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 546.0
HKD3_k127_4757429_1 Sulfate permease K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 499.0
HKD3_k127_4757429_2 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 440.0
HKD3_k127_4757429_3 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 445.0
HKD3_k127_4757429_4 Protein of unknown function (DUF1269) - - - 0.000000000000000000000000002056 118.0
HKD3_k127_4840398_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.000000000000000000000000000000000000000009097 159.0
HKD3_k127_4840398_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000007806 152.0
HKD3_k127_4840398_2 helix_turn_helix, Lux Regulon - - - 0.00008006 51.0
HKD3_k127_484971_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 438.0
HKD3_k127_484971_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000001636 235.0
HKD3_k127_484971_2 Uncharacterized conserved protein (DUF2277) - - - 0.00000000000000004198 87.0
HKD3_k127_4862839_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0000731,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 3.645e-210 704.0
HKD3_k127_4862839_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 319.0
HKD3_k127_4862839_2 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000001216 183.0
HKD3_k127_4862839_3 - - - - 0.0000000000000000000000000676 117.0
HKD3_k127_4862839_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000001361 111.0
HKD3_k127_4862839_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000004394 93.0
HKD3_k127_4862839_6 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.000000000000002114 91.0
HKD3_k127_4862839_7 EamA-like transporter family - - - 0.00000000003846 74.0
HKD3_k127_4882718_0 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 395.0
HKD3_k127_4882718_1 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000002421 164.0
HKD3_k127_4882718_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000003811 90.0
HKD3_k127_4927172_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 547.0
HKD3_k127_4927172_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 531.0
HKD3_k127_4927172_10 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000864 218.0
HKD3_k127_4927172_11 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029 - - 0.0000000000000000000000000000000000000000000000000000000004376 213.0
HKD3_k127_4927172_12 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000004839 200.0
HKD3_k127_4927172_13 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000007067 155.0
HKD3_k127_4927172_14 Putative NAD(P)-binding K03499 - - 0.00000000000000000000000000000001526 138.0
HKD3_k127_4927172_15 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000003365 137.0
HKD3_k127_4927172_16 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000005215 128.0
HKD3_k127_4927172_17 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000199 103.0
HKD3_k127_4927172_18 Universal stress protein family - - - 0.0000000000000000000009769 101.0
HKD3_k127_4927172_19 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000001821 99.0
HKD3_k127_4927172_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 505.0
HKD3_k127_4927172_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 303.0
HKD3_k127_4927172_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 297.0
HKD3_k127_4927172_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 308.0
HKD3_k127_4927172_6 pfam abc K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002194 287.0
HKD3_k127_4927172_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000008051 232.0
HKD3_k127_4927172_8 domain protein K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000004519 224.0
HKD3_k127_4927172_9 Belongs to the bacterial solute-binding protein 3 family - - - 0.0000000000000000000000000000000000000000000000000000000000004824 231.0
HKD3_k127_4928933_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 432.0
HKD3_k127_4928933_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 371.0
HKD3_k127_4928933_2 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000000000000000001692 219.0
HKD3_k127_4928933_3 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000008052 136.0
HKD3_k127_4928933_4 Virulence factor - - - 0.0000000000000000000008753 107.0
HKD3_k127_4934480_0 malic protein domain protein K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 593.0
HKD3_k127_4934480_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 460.0
HKD3_k127_4934480_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000004975 105.0
HKD3_k127_4934480_3 Domain of unknown function (DUF4349) - - - 0.000000000003663 75.0
HKD3_k127_4934480_4 Belongs to the universal stress protein A family - - - 0.0000000006067 67.0
HKD3_k127_4943368_0 metallopeptidase activity K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 496.0
HKD3_k127_4943368_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000152 274.0
HKD3_k127_4943368_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000006404 209.0
HKD3_k127_4943368_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000343 201.0
HKD3_k127_4943368_4 R3H domain - - - 0.0000000000000000000000000000000000002149 156.0
HKD3_k127_4943368_5 glyoxalase - - - 0.0000000000000000000000000689 112.0
HKD3_k127_4943368_6 ECF sigma factor K03088 - - 0.0000000000000000000000002164 114.0
HKD3_k127_4943368_7 Two component regulator propeller - - - 0.00000001521 68.0
HKD3_k127_4946460_0 helix_turn_helix, Lux Regulon K03556 - - 1.083e-258 827.0
HKD3_k127_4946460_1 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001121 272.0
HKD3_k127_4946460_2 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000003654 177.0
HKD3_k127_4946460_3 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000003221 151.0
HKD3_k127_4946460_4 - - - - 0.0000000000000000000004438 102.0
HKD3_k127_4946460_5 ABC-2 family transporter protein K01992 - - 0.0000000000000005648 79.0
HKD3_k127_4959765_0 glycosyl K16444 - 2.4.1.310 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 575.0
HKD3_k127_4959765_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 476.0
HKD3_k127_4959765_2 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 361.0
HKD3_k127_4959765_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 319.0
HKD3_k127_4959765_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000147 183.0
HKD3_k127_4959765_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000003644 117.0
HKD3_k127_4961245_0 ABC transporter, transmembrane region K06147 - - 9.28e-255 831.0
HKD3_k127_4961245_1 ABC transporter, transmembrane region K06147 - - 5.971e-227 716.0
HKD3_k127_4961245_10 PFAM regulatory protein GntR HTH K22293 - - 0.000000000000000000000000000000000000000000000000000000000000000000001957 255.0
HKD3_k127_4961245_11 Amidohydrolase family K01443 - 3.5.1.25 0.000000000000000000000000000000000000000000000000000000000000000002495 242.0
HKD3_k127_4961245_12 Transcriptional regulator, MarR family - - - 0.0000000000000000000000003236 113.0
HKD3_k127_4961245_13 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000149 109.0
HKD3_k127_4961245_14 Iron-binding zinc finger CDGSH type - - - 0.000000000000000003335 91.0
HKD3_k127_4961245_15 Dihydroxyacetone kinase K05879 - 2.7.1.121 0.00000000000003565 83.0
HKD3_k127_4961245_16 Cold shock protein K03704 - - 0.0000000007843 67.0
HKD3_k127_4961245_17 Cupin 2, conserved barrel domain protein K00450,K01628 - 1.13.11.4,4.1.2.17 0.00000008941 58.0
HKD3_k127_4961245_2 trimethylamine methyltransferase K14083 - 2.1.1.250 1.632e-200 632.0
HKD3_k127_4961245_3 Dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 554.0
HKD3_k127_4961245_4 Uncharacterised protein family (UPF0261) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 494.0
HKD3_k127_4961245_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 465.0
HKD3_k127_4961245_6 Dak1 domain K00863,K05878,K05879 - 2.7.1.121,2.7.1.28,2.7.1.29,4.6.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 419.0
HKD3_k127_4961245_7 carbohydrate kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008683 438.0
HKD3_k127_4961245_8 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 352.0
HKD3_k127_4961245_9 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 329.0
HKD3_k127_4973262_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 447.0
HKD3_k127_4973262_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 347.0
HKD3_k127_4973262_2 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000005994 261.0
HKD3_k127_4973262_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000001685 265.0
HKD3_k127_4973262_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000004696 222.0
HKD3_k127_4973262_5 Dienelactone hydrolase family - - - 0.0000000000000000000000000000003545 127.0
HKD3_k127_4973262_6 permease - - - 0.0000000000000000004253 101.0
HKD3_k127_4973262_7 PFAM FAD dependent oxidoreductase - - - 0.0000000001056 62.0
HKD3_k127_4973980_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 6.163e-258 814.0
HKD3_k127_4973980_1 tRNA binding K04566 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 366.0
HKD3_k127_4973980_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000002598 230.0
HKD3_k127_4973980_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000004532 167.0
HKD3_k127_4973980_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000842 156.0
HKD3_k127_4973980_5 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000004068 121.0
HKD3_k127_4973980_6 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05568 - 1.6.5.3 0.0000000000004867 83.0
HKD3_k127_4983582_0 ABC-type sugar transport system, periplasmic component K02027,K10227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 452.0
HKD3_k127_4983582_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K11381,K21416,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003204 260.0
HKD3_k127_4983582_2 DeoR C terminal sensor domain K03436 - - 0.0000000000000000000000000000000000000000000635 172.0
HKD3_k127_5018076_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001497 302.0
HKD3_k127_5018076_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000654 298.0
HKD3_k127_5018076_2 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008614 246.0
HKD3_k127_5018076_3 asparaginase activity K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000008062 226.0
HKD3_k127_5018076_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000002923 191.0
HKD3_k127_5018076_5 Multidrug efflux transporter, MFS family protein - - - 0.0000000000001702 80.0
HKD3_k127_5025865_0 DEAD DEAH box helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 496.0
HKD3_k127_5025865_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 440.0
HKD3_k127_5025865_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 355.0
HKD3_k127_5025865_3 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 325.0
HKD3_k127_5025865_4 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000161 203.0
HKD3_k127_5025865_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000295 128.0
HKD3_k127_5025865_6 - - - - 0.000000000000000000000003135 115.0
HKD3_k127_5025865_8 ROK family K00845 - 2.7.1.2 0.000000000002994 80.0
HKD3_k127_5025865_9 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.000001267 53.0
HKD3_k127_5042525_0 electron transport chain K00347,K03614,K21163 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 300.0
HKD3_k127_5043846_0 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 387.0
HKD3_k127_5043846_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000141 263.0
HKD3_k127_5043846_2 transcriptional regulator, SARP family - - - 0.00000000000000000000000000000000000000005244 175.0
HKD3_k127_5043846_3 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006104,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 - 0.00000000000000000000000000000000000131 142.0
HKD3_k127_505527_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.0000000000000000000000000000000000001009 160.0
HKD3_k127_505527_1 - - - - 0.000000000000001362 85.0
HKD3_k127_5057556_0 PFAM Lipopolysaccharide kinase (Kdo WaaP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 419.0
HKD3_k127_5057556_1 Acetyltransferase (GNAT) domain - - - 0.000000001141 67.0
HKD3_k127_5063585_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 354.0
HKD3_k127_5063585_1 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000002126 243.0
HKD3_k127_5063585_2 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000001828 213.0
HKD3_k127_5063585_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000001961 182.0
HKD3_k127_5063585_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000372 148.0
HKD3_k127_5063585_5 Trp repressor protein - - - 0.000000000000000000003403 96.0
HKD3_k127_5063585_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000138 82.0
HKD3_k127_5077220_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03336 - 3.7.1.22 7.391e-274 857.0
HKD3_k127_5077220_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K12952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 558.0
HKD3_k127_5077220_10 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000001484 154.0
HKD3_k127_5077220_11 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000716 112.0
HKD3_k127_5077220_12 Pfam:DUF59 - - - 0.000000000001177 72.0
HKD3_k127_5077220_13 Protein of unknown function (DUF433) - - - 0.0003437 49.0
HKD3_k127_5077220_2 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004144 437.0
HKD3_k127_5077220_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 391.0
HKD3_k127_5077220_4 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 401.0
HKD3_k127_5077220_5 COGs COG0673 dehydrogenase and related protein K00010 - 1.1.1.18,1.1.1.369 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 367.0
HKD3_k127_5077220_6 Inosose dehydratase K03335 - 4.2.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 381.0
HKD3_k127_5077220_7 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000259 218.0
HKD3_k127_5077220_8 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000004955 211.0
HKD3_k127_5077220_9 Belongs to the BI1 family K06890 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000001102 162.0
HKD3_k127_5088762_0 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 448.0
HKD3_k127_5088762_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 354.0
HKD3_k127_5088762_2 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 295.0
HKD3_k127_5088762_3 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000002025 196.0
HKD3_k127_5088762_4 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000002537 155.0
HKD3_k127_5088762_5 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000000000000000007439 138.0
HKD3_k127_5090415_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 542.0
HKD3_k127_5090415_1 PFAM Glycosyl transferase family 2 K00694 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 509.0
HKD3_k127_5090415_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 375.0
HKD3_k127_5090415_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 350.0
HKD3_k127_5090415_4 PFAM Metallophosphoesterase K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 293.0
HKD3_k127_5090415_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000003787 220.0
HKD3_k127_5090415_6 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000008763 192.0
HKD3_k127_5126480_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 436.0
HKD3_k127_5126480_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 414.0
HKD3_k127_5126480_10 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000002898 177.0
HKD3_k127_5126480_11 regulatory protein - - - 0.0000000000000000000000000000000000000000006197 179.0
HKD3_k127_5126480_12 MOSC domain - - - 0.000000000000003004 89.0
HKD3_k127_5126480_13 - - - - 0.0000000000562 70.0
HKD3_k127_5126480_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 360.0
HKD3_k127_5126480_3 Bacterial extracellular solute-binding protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 324.0
HKD3_k127_5126480_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 301.0
HKD3_k127_5126480_5 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002276 288.0
HKD3_k127_5126480_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000002759 270.0
HKD3_k127_5126480_7 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002634 277.0
HKD3_k127_5126480_8 TIGRFAM competence damage-inducible protein CinA N-terminal domain K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000003055 250.0
HKD3_k127_5126480_9 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000003969 212.0
HKD3_k127_5152450_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 606.0
HKD3_k127_5152450_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000001246 121.0
HKD3_k127_5163661_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.537e-229 726.0
HKD3_k127_5163661_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 536.0
HKD3_k127_5163661_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 366.0
HKD3_k127_5202180_0 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004508 355.0
HKD3_k127_5202180_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 336.0
HKD3_k127_5202180_2 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000001688 265.0
HKD3_k127_5202180_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000152 61.0
HKD3_k127_5205301_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 589.0
HKD3_k127_5205301_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 437.0
HKD3_k127_5205301_10 Helix-hairpin-helix motif K02237 - - 0.0000000000000000000002375 108.0
HKD3_k127_5205301_11 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000009255 59.0
HKD3_k127_5205301_2 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 290.0
HKD3_k127_5205301_3 Competence protein ComEC K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000001037 265.0
HKD3_k127_5205301_4 EamA-like transporter family K11939 - - 0.0000000000000000000000000000000000000000000000000000000005378 213.0
HKD3_k127_5205301_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000004925 198.0
HKD3_k127_5205301_6 SMART Peptidoglycan-binding LysM - - - 0.0000000000000000000000000000000000000000001596 178.0
HKD3_k127_5205301_7 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000001157 162.0
HKD3_k127_5205301_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000002058 129.0
HKD3_k127_5205301_9 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000001507 114.0
HKD3_k127_5265571_0 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 442.0
HKD3_k127_5265571_1 F420H(2)-dependent quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000002017 212.0
HKD3_k127_5265571_2 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000001186 163.0
HKD3_k127_5265571_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000001055 104.0
HKD3_k127_5316535_0 Capsule synthesis protein, CapA K07282 - - 0.00000000000000000000000000000000000000000000000000000000000004511 237.0
HKD3_k127_5316535_1 A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics K18455 GO:0003674,GO:0005488,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010126,GO:0010127,GO:0016137,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051186,GO:0071704,GO:0098754,GO:1901135,GO:1901657 3.5.1.115 0.0000000000003835 72.0
HKD3_k127_5320105_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 377.0
HKD3_k127_5320105_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002909 278.0
HKD3_k127_5320105_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002168 266.0
HKD3_k127_5320105_3 rod shape-determining protein MreD K03571 - - 0.0005605 51.0
HKD3_k127_533036_0 Acyl- CoA dehydrogenase type 2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 576.0
HKD3_k127_533036_1 ATP-NAD kinase - - - 0.000000000000000000000000107 108.0
HKD3_k127_5334777_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000287 260.0
HKD3_k127_5334777_1 Peptidase M23 K21471 - - 0.0000000000000000000000000104 125.0
HKD3_k127_533638_0 Belongs to the glycosyl hydrolase 13 family - - - 6.663e-268 859.0
HKD3_k127_533638_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 353.0
HKD3_k127_533638_10 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000002988 115.0
HKD3_k127_533638_11 - - - - 0.0000000000000004499 90.0
HKD3_k127_533638_12 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000008522 82.0
HKD3_k127_533638_13 Methyltransferase domain - - - 0.0000002853 62.0
HKD3_k127_533638_14 Bacterial Ig-like domain (group 3) K20276 - - 0.00002018 57.0
HKD3_k127_533638_2 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 314.0
HKD3_k127_533638_3 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 295.0
HKD3_k127_533638_4 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000009459 265.0
HKD3_k127_533638_5 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000005578 251.0
HKD3_k127_533638_6 response regulator receiver K07658,K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000001503 230.0
HKD3_k127_533638_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000007582 195.0
HKD3_k127_533638_8 spore germination - - - 0.000000000000000000000000000000000000000000000001308 188.0
HKD3_k127_533638_9 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000003427 142.0
HKD3_k127_5359662_0 protein involved in exopolysaccharide biosynthesis - - - 8.365e-210 674.0
HKD3_k127_5359662_1 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 567.0
HKD3_k127_5359662_10 COG2017 Galactose mutarotase and related enzymes K01785 - 5.1.3.3 0.000000000000000000000004035 113.0
HKD3_k127_5359662_2 Xaa-Pro aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 511.0
HKD3_k127_5359662_3 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 461.0
HKD3_k127_5359662_4 Belongs to the binding-protein-dependent transport system permease family K10544 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015749,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034219,GO:0044425,GO:0044464,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007891 435.0
HKD3_k127_5359662_5 ABC transporter, ATP-binding protein K10545 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 354.0
HKD3_k127_5359662_6 ROK family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003053 320.0
HKD3_k127_5359662_7 TIGRFAM D-xylose ABC transporter K10543 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005975,GO:0005996,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0015749,GO:0015750,GO:0015753,GO:0019321,GO:0030246,GO:0030288,GO:0030313,GO:0031975,GO:0034219,GO:0036094,GO:0042597,GO:0042732,GO:0044238,GO:0044281,GO:0044464,GO:0048029,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 299.0
HKD3_k127_5359662_8 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 303.0
HKD3_k127_5359662_9 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004487 282.0
HKD3_k127_5365201_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 411.0
HKD3_k127_5365201_1 PFAM ABC transporter related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 341.0
HKD3_k127_5365201_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 313.0
HKD3_k127_5365201_3 PFAM FAD linked oxidase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001001 283.0
HKD3_k127_5365201_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000563 232.0
HKD3_k127_5365201_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000001934 212.0
HKD3_k127_5365201_6 TAP-like protein - - - 0.0000000000000000000000000000000000000000000000000775 196.0
HKD3_k127_5365201_7 Cupin 2, conserved barrel domain protein K19547 - 5.3.3.19 0.000000000000000000000000000002224 131.0
HKD3_k127_5365201_8 DinB family - - - 0.000000000000001483 89.0
HKD3_k127_5369501_0 Glycine cleavage system P-protein K00283 - 1.4.4.2 2.548e-263 829.0
HKD3_k127_5369501_1 Aminotransferase class-V - - - 1.418e-256 803.0
HKD3_k127_5369501_10 Nucleoside H+ symporter K05820 - - 0.00000000000000000000000000000000002762 149.0
HKD3_k127_5369501_11 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000003462 151.0
HKD3_k127_5369501_12 - - - - 0.00000000000000000000000000018 122.0
HKD3_k127_5369501_13 Pfam:Pyridox_oxidase - - - 0.000000000000000000000284 111.0
HKD3_k127_5369501_14 Zincin-like metallopeptidase - - - 0.000000000000004139 81.0
HKD3_k127_5369501_2 - - - - 5.967e-237 756.0
HKD3_k127_5369501_3 FAD linked oxidases, C-terminal domain K00102,K00803 - 1.1.2.4,2.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 603.0
HKD3_k127_5369501_4 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 589.0
HKD3_k127_5369501_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 547.0
HKD3_k127_5369501_6 FGGY family of carbohydrate kinases, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 527.0
HKD3_k127_5369501_7 Mut7-C ubiquitin K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001095 259.0
HKD3_k127_5369501_8 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001369 246.0
HKD3_k127_5369501_9 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000008397 249.0
HKD3_k127_5449807_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 438.0
HKD3_k127_5449807_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000001762 136.0
HKD3_k127_5531682_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005094 274.0
HKD3_k127_5531682_1 Ribosomal protein S3, C-terminal domain K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007727 264.0
HKD3_k127_5531682_10 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000002064 92.0
HKD3_k127_5531682_11 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0009013 48.0
HKD3_k127_5531682_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000123 240.0
HKD3_k127_5531682_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000001305 209.0
HKD3_k127_5531682_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000007371 190.0
HKD3_k127_5531682_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000001278 173.0
HKD3_k127_5531682_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000046 134.0
HKD3_k127_5531682_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000009588 121.0
HKD3_k127_5531682_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000005855 120.0
HKD3_k127_5531682_9 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000002013 107.0
HKD3_k127_5560271_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.199e-241 758.0
HKD3_k127_5560271_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 343.0
HKD3_k127_5560271_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000002964 121.0
HKD3_k127_5560271_3 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism - - - 0.000000000004383 74.0
HKD3_k127_5587646_0 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.000000006599 58.0
HKD3_k127_5587646_1 HAD-hyrolase-like K20862 - 3.1.3.102,3.1.3.104 0.000000007001 67.0
HKD3_k127_56181_0 transferase K02851 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0016740,GO:0016772,GO:0016780,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000001439 236.0
HKD3_k127_56181_1 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000001026 159.0
HKD3_k127_56181_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000001047 146.0
HKD3_k127_56181_3 ATP synthase F(0) sector subunit b K02109 - - 0.0000000000000005639 85.0
HKD3_k127_56181_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000003403 64.0
HKD3_k127_56181_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000001062 57.0
HKD3_k127_56181_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000002589 60.0
HKD3_k127_56181_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00003034 49.0
HKD3_k127_5634868_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 407.0
HKD3_k127_5659967_0 PFAM ABC transporter related K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 594.0
HKD3_k127_5659967_1 DNA polymerase K02337 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 527.0
HKD3_k127_5659967_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 406.0
HKD3_k127_5659967_3 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003183 276.0
HKD3_k127_5659967_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004379 262.0
HKD3_k127_5659967_5 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000004571 196.0
HKD3_k127_5659967_6 CoA binding domain K01740,K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.49 0.000000000000000000000000000000000001689 145.0
HKD3_k127_5682018_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000001808 228.0
HKD3_k127_5682018_1 - - - - 0.00000000000000000000000000000000000000000000000000000000005037 212.0
HKD3_k127_5682018_2 PIN domain - - - 0.00000000000000000000000000000000000000003567 155.0
HKD3_k127_5682018_3 toxin-antitoxin pair type II binding - - - 0.000000000000000000000002801 104.0
HKD3_k127_5682018_4 - - - - 0.00000001867 63.0
HKD3_k127_5729565_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008496 303.0
HKD3_k127_5729565_1 PFAM ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000001239 167.0
HKD3_k127_593879_0 Thiopurine S-methyltransferase (TPMT) - - - 0.00000000000000000000000000000000000000000000000000000002905 206.0
HKD3_k127_593879_1 methyltransferase K16129 - - 0.0000000000000000000000000000000000006419 149.0
HKD3_k127_593879_2 bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000009967 136.0
HKD3_k127_593879_3 - - - - 0.0000000000000000000001291 107.0
HKD3_k127_593879_4 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000002405 60.0
HKD3_k127_5940872_0 purine-nucleoside phosphorylase activity K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 429.0
HKD3_k127_5940872_1 Helix-hairpin-helix class 2 (Pol1 family) motifs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 331.0
HKD3_k127_5940872_2 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000000006166 211.0
HKD3_k127_5940872_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000002199 170.0
HKD3_k127_5940872_4 PFAM inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000004097 153.0
HKD3_k127_5940872_5 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.000000000000007218 80.0
HKD3_k127_5970182_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015934,GO:0016020,GO:0016043,GO:0019219,GO:0019222,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0031323,GO:0031325,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000232,GO:2000234 - 0.000000000000000000000000000000000000000000000000000000000000000000000007717 248.0
HKD3_k127_5970182_1 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000007351 169.0
HKD3_k127_5970182_2 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000004065 180.0
HKD3_k127_5970182_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000001648 64.0
HKD3_k127_6037600_0 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 475.0
HKD3_k127_6037600_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 449.0
HKD3_k127_6037600_2 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 426.0
HKD3_k127_6037600_3 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 331.0
HKD3_k127_6037600_4 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 334.0
HKD3_k127_6037600_5 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000005255 284.0
HKD3_k127_6037600_6 exopeptidase activity - - - 0.000000000262 71.0
HKD3_k127_6046611_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system - - - 2.29e-249 816.0
HKD3_k127_6046611_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 7.097e-205 655.0
HKD3_k127_6046611_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 306.0
HKD3_k127_6046611_3 Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 285.0
HKD3_k127_6046611_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907,K01908 - 6.2.1.1,6.2.1.16,6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009853 267.0
HKD3_k127_6046611_5 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000004722 218.0
HKD3_k127_6046611_6 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000006714 211.0
HKD3_k127_6046611_7 SPTR D1CGX5 Response regulator receiver protein - - - 0.0000000000000001338 89.0
HKD3_k127_6050279_0 Periplasmic binding protein domain K02058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 325.0
HKD3_k127_6050279_1 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 326.0
HKD3_k127_6050279_2 COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism General function prediction only - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 296.0
HKD3_k127_6050279_3 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000473 278.0
HKD3_k127_6050279_4 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000524 276.0
HKD3_k127_6050279_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000009755 235.0
HKD3_k127_6050279_6 PFAM Xylose isomerase domain protein TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000006717 218.0
HKD3_k127_6050279_7 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.0000000000000000000000000000000000000000000000000000004771 205.0
HKD3_k127_6050279_8 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.0000000000000000000000000000000000000000000006281 177.0
HKD3_k127_6050279_9 Spermidine putrescine ABC transporter substrate-binding protein K11069 - - 0.0000000000000002121 92.0
HKD3_k127_605051_0 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 437.0
HKD3_k127_605051_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 398.0
HKD3_k127_605051_10 NlpC/P60 family K21471 - - 0.00000000000001915 82.0
HKD3_k127_605051_11 heat shock protein binding - - - 0.00000002436 65.0
HKD3_k127_605051_2 Exporter of polyketide antibiotics K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 382.0
HKD3_k127_605051_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 353.0
HKD3_k127_605051_4 response to copper ion - - - 0.00000000000000000000000000000000000000000007976 180.0
HKD3_k127_605051_5 TIGRFAM Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.0000000000000000000000000000000000000001718 170.0
HKD3_k127_605051_6 DinB family - - - 0.00000000000000000000000000000000000198 145.0
HKD3_k127_605051_7 Rossmann-like domain K06988 - 1.5.1.40 0.000000000000000000000000000000000003687 144.0
HKD3_k127_605051_8 domain, Protein - - - 0.000000000000000000000000000000000007013 155.0
HKD3_k127_605051_9 ChrB domain-containing protein - - - 0.00000000000000000000000000006835 122.0
HKD3_k127_6051121_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 6.2.1.1 2.911e-310 962.0
HKD3_k127_6051121_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 441.0
HKD3_k127_6051121_10 DNA methylAse K01155 - 3.1.21.4 0.00002752 58.0
HKD3_k127_6051121_2 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 375.0
HKD3_k127_6051121_3 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 358.0
HKD3_k127_6051121_4 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 304.0
HKD3_k127_6051121_5 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005186 286.0
HKD3_k127_6051121_6 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000002056 181.0
HKD3_k127_6051121_7 Mechanosensitive ion channel K22044 - - 0.000000000000000000000000000000000000000009861 166.0
HKD3_k127_6051121_8 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000008711 136.0
HKD3_k127_6051121_9 NUBPL iron-transfer P-loop NTPase K02282 - - 0.000000000000000000000000000001847 138.0
HKD3_k127_6054127_0 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002033 275.0
HKD3_k127_6054127_1 - - - - 0.000000000000000000000000000000000000000006751 163.0
HKD3_k127_6065329_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 GO:0003674,GO:0003824,GO:0004611,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008964,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044444,GO:0044464 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 634.0
HKD3_k127_6065329_1 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 580.0
HKD3_k127_6065329_2 Binding-protein-dependent transport system inner membrane component K15599 - - 0.000000000000000000000000000000000000000000000000000000000000291 214.0
HKD3_k127_6065329_3 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000001585 218.0
HKD3_k127_6065329_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000007378 133.0
HKD3_k127_6066704_0 xanthine dehydrogenase activity - - - 7.513e-196 638.0
HKD3_k127_6066704_1 Amidohydrolase family K01487 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006144,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008892,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0016814,GO:0018756,GO:0019239,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0046098,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072521,GO:1901360,GO:1901564 3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 320.0
HKD3_k127_6066704_2 UDP-glucoronosyl and UDP-glucosyl transferase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0020012,GO:0030682,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044464,GO:0046467,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071704,GO:0071944,GO:0075136,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000002206 239.0
HKD3_k127_6066704_3 PFAM 2Fe-2S -binding K03518,K13483 - 1.2.5.3 0.00000003824 67.0
HKD3_k127_6068289_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 489.0
HKD3_k127_6068289_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 386.0
HKD3_k127_6068289_2 Peptidase family S51 - - - 0.0000000000000000000000000000000000000000000000000000000000006907 241.0
HKD3_k127_6068289_3 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.00000000000000000000000002472 121.0
HKD3_k127_6077990_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 9.887e-226 710.0
HKD3_k127_6077990_1 PFAM Bacterial regulatory proteins, luxR family K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 344.0
HKD3_k127_6085539_0 Carboxyl transferase domain K01969 - 6.4.1.4 2.835e-233 759.0
HKD3_k127_6085539_1 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 523.0
HKD3_k127_6085539_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 459.0
HKD3_k127_6085539_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051716,GO:0071496,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000885 229.0
HKD3_k127_6085539_4 MOSC domain - - - 0.00000000000000000000000000000000002221 147.0
HKD3_k127_6085539_5 - - - - 0.000000007299 68.0
HKD3_k127_6090035_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008156 323.0
HKD3_k127_6090035_1 GMC oxidoreductase K03333 - 1.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000002274 248.0
HKD3_k127_6090035_2 PFAM Metal-dependent phosphohydrolase, HD K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000002267 204.0
HKD3_k127_6096969_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 390.0
HKD3_k127_6096969_1 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003863 361.0
HKD3_k127_6096969_2 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004675 273.0
HKD3_k127_6096969_3 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001697 258.0
HKD3_k127_6096969_4 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000002411 207.0
HKD3_k127_6096969_5 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000004335 202.0
HKD3_k127_6096969_6 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.00000000000000000302 85.0
HKD3_k127_6122153_0 aerobic electron transport chain K00425 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016679,GO:0016682,GO:0019646,GO:0020037,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0070069,GO:0071944,GO:0097159,GO:1901363 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 464.0
HKD3_k127_6122153_1 Histidine kinase-like ATPases K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 404.0
HKD3_k127_6122153_10 EamA-like transporter family - - - 0.0000002456 62.0
HKD3_k127_6122153_2 oxidase, subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 351.0
HKD3_k127_6122153_3 AAA domain, putative AbiEii toxin, Type IV TA system K02028,K02029 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 341.0
HKD3_k127_6122153_4 Binding-protein-dependent transport system inner membrane component K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 297.0
HKD3_k127_6122153_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003801 295.0
HKD3_k127_6122153_6 Bacterial periplasmic substrate-binding proteins K02030,K02424,K17073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003556 276.0
HKD3_k127_6122153_7 WYL domain K07012,K13572 - - 0.000000000000000000000000000000000000000000000000000000001379 225.0
HKD3_k127_6122153_8 helix_turn_helix, Lux Regulon - - - 0.000000000000000001506 98.0
HKD3_k127_6122153_9 PFAM Peptidase family M23 - - - 0.0000000000001538 81.0
HKD3_k127_6128789_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 7.602e-236 743.0
HKD3_k127_6128789_1 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003975 485.0
HKD3_k127_6128789_2 Participates in initiation and elongation during chromosome replication K02314,K02316,K17680 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000001928 254.0
HKD3_k127_6128789_3 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000001982 193.0
HKD3_k127_6128789_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000003118 179.0
HKD3_k127_6128789_5 CAAX protease self-immunity K07052 - - 0.0000000000000000000004364 111.0
HKD3_k127_6128789_6 amine dehydrogenase activity - - - 0.000000000000000000004732 109.0
HKD3_k127_6128789_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000002466 57.0
HKD3_k127_6128789_8 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0001077 50.0
HKD3_k127_6146409_0 PFAM Helicase conserved C-terminal domain K06877 - - 3.583e-260 824.0
HKD3_k127_6146409_1 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 395.0
HKD3_k127_6146409_10 Pilus assembly protein K02282 - - 0.00000000000000000000000003782 122.0
HKD3_k127_6146409_11 PFAM PfkB domain protein - - - 0.00000000000004143 84.0
HKD3_k127_6146409_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 354.0
HKD3_k127_6146409_3 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 303.0
HKD3_k127_6146409_4 Peptidase dimerisation domain K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002295 276.0
HKD3_k127_6146409_5 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001519 264.0
HKD3_k127_6146409_6 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004501 252.0
HKD3_k127_6146409_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0000270,GO:0003674,GO:0003824,GO:0004857,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008657,GO:0008881,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0010911,GO:0016020,GO:0016853,GO:0016854,GO:0016855,GO:0030203,GO:0030234,GO:0032780,GO:0034645,GO:0036361,GO:0042030,GO:0042546,GO:0043086,GO:0043170,GO:0043462,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0047661,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0072586,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:2000371,GO:2000372 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000001888 220.0
HKD3_k127_6146409_8 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000000007109 193.0
HKD3_k127_6146409_9 Methyltransferase type 12 - - - 0.00000000000000000000000000000002746 143.0
HKD3_k127_6149440_0 Belongs to the citrate synthase family K01647 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008514 608.0
HKD3_k127_6149440_1 Serine hydrolase involved in the detoxification of formaldehyde - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 292.0
HKD3_k127_6149440_2 Capsule synthesis protein, CapA K07282 - - 0.000000000000000000000000000000000000000000000000000000001587 221.0
HKD3_k127_6151414_0 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 316.0
HKD3_k127_6151414_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 313.0
HKD3_k127_6151414_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000001686 99.0
HKD3_k127_6151414_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000007945 63.0
HKD3_k127_6151954_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 549.0
HKD3_k127_6151954_1 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 518.0
HKD3_k127_6151954_10 Belongs to the UPF0354 family - - - 0.000007715 59.0
HKD3_k127_6151954_2 glutamine synthetase K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 399.0
HKD3_k127_6151954_3 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 349.0
HKD3_k127_6151954_4 PFAM Enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000004107 270.0
HKD3_k127_6151954_5 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000000000000000000000000000000000000000000002592 179.0
HKD3_k127_6151954_6 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000001754 161.0
HKD3_k127_6151954_7 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000006926 140.0
HKD3_k127_6151954_8 PFAM alpha beta hydrolase fold K01055 - 3.1.1.24 0.000000000000000000001506 107.0
HKD3_k127_6151954_9 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000403 70.0
HKD3_k127_6156551_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007496 245.0
HKD3_k127_6156551_1 Phosphatidylethanolamine-binding protein - - - 0.000000000000000000000000000000002079 137.0
HKD3_k127_6156551_2 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000001453 106.0
HKD3_k127_6163233_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 7.657e-305 960.0
HKD3_k127_6163233_1 TIGRFAM histidinol-phosphate phosphatase HisN, inositol monophosphatase family K01092,K05602 - 3.1.3.15,3.1.3.25 0.00000000000000000000000000000000000000000000000000000004148 220.0
HKD3_k127_6163233_2 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000001807 147.0
HKD3_k127_6163679_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000002311 228.0
HKD3_k127_6164970_0 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 380.0
HKD3_k127_6164970_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 301.0
HKD3_k127_6164970_2 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000136 275.0
HKD3_k127_6164970_3 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000004144 174.0
HKD3_k127_6164970_4 'Molybdopterin - - - 0.00000000000000000000000000000000000000000002886 177.0
HKD3_k127_6172157_0 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000006709 201.0
HKD3_k127_6172157_2 ABC-2 family transporter protein - - - 0.00009412 53.0
HKD3_k127_6191528_0 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 409.0
HKD3_k127_6191528_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000004199 171.0
HKD3_k127_6191528_2 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000007953 121.0
HKD3_k127_6196540_0 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002008 291.0
HKD3_k127_6196540_1 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000008074 151.0
HKD3_k127_6196540_2 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000003812 136.0
HKD3_k127_6200019_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.389e-233 750.0
HKD3_k127_6200019_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 1.635e-196 640.0
HKD3_k127_6200019_10 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 322.0
HKD3_k127_6200019_11 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 336.0
HKD3_k127_6200019_12 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001155 264.0
HKD3_k127_6200019_13 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000003335 257.0
HKD3_k127_6200019_14 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000002205 239.0
HKD3_k127_6200019_15 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000002871 230.0
HKD3_k127_6200019_16 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000009884 216.0
HKD3_k127_6200019_17 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000006367 194.0
HKD3_k127_6200019_18 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000003891 176.0
HKD3_k127_6200019_19 NADP transhydrogenase K00324 - 1.6.1.2 0.000000000000000000000000000000000003301 144.0
HKD3_k127_6200019_2 the transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 514.0
HKD3_k127_6200019_20 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000001951 143.0
HKD3_k127_6200019_21 TRANSCRIPTIONal - - - 0.000000000000000000000000001152 130.0
HKD3_k127_6200019_22 Pfam:DUF385 - - - 0.000000000000000000000001674 116.0
HKD3_k127_6200019_23 AAA domain - - - 0.000000000000000000000003512 112.0
HKD3_k127_6200019_24 Domain of unknown function (DUF4342) - - - 0.00000000000000000001446 97.0
HKD3_k127_6200019_25 spore germination K03605 - - 0.0000000000000000006931 94.0
HKD3_k127_6200019_26 Protein of unknown function (DUF3419) K13622 - - 0.000000000000000002933 99.0
HKD3_k127_6200019_27 DSBA-like thioredoxin domain - - - 0.000000000000000368 87.0
HKD3_k127_6200019_28 PspC domain K03973 - - 0.0000000000005724 75.0
HKD3_k127_6200019_29 Cell wall-active antibiotics response 4TMS YvqF - - - 0.000000000002017 76.0
HKD3_k127_6200019_3 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 495.0
HKD3_k127_6200019_30 PFAM Two component regulator propeller - - - 0.00000002063 67.0
HKD3_k127_6200019_31 PFAM amino acid-binding ACT domain protein - - - 0.000008046 56.0
HKD3_k127_6200019_33 Cupredoxin-like domain - - - 0.00006916 51.0
HKD3_k127_6200019_4 PFAM alanine dehydrogenase PNT domain protein K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 427.0
HKD3_k127_6200019_5 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 359.0
HKD3_k127_6200019_6 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 364.0
HKD3_k127_6200019_7 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 337.0
HKD3_k127_6200019_8 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 332.0
HKD3_k127_6200019_9 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 330.0
HKD3_k127_6209557_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 467.0
HKD3_k127_6209557_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 338.0
HKD3_k127_6209557_2 zinc metalloprotease K04771,K11749,K16922 GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0016021,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0040007,GO:0043170,GO:0043856,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0045152,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:0140110,GO:1901564,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 3.4.21.107 0.00000000000000000000000000000000000000000000000000027 198.0
HKD3_k127_6209557_3 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000333 142.0
HKD3_k127_6209557_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000001915 55.0
HKD3_k127_6209743_0 ABC transporter K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 436.0
HKD3_k127_6209743_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 413.0
HKD3_k127_6209743_2 Bacterial extracellular solute-binding protein K02055 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 389.0
HKD3_k127_6209743_3 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 347.0
HKD3_k127_6209743_4 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002877 327.0
HKD3_k127_6209743_5 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000001042 263.0
HKD3_k127_6209743_6 Binding-protein-dependent transport systems inner membrane component K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001784 248.0
HKD3_k127_6209743_7 Luciferase-like monooxygenase - - - 0.0000000000000000000000000000000000000000000000000000002071 208.0
HKD3_k127_6209743_8 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000000006073 128.0
HKD3_k127_6209743_9 cyclic-guanylate-specific phosphodiesterase activity - - - 0.00001567 57.0
HKD3_k127_6219915_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 453.0
HKD3_k127_6219915_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030312,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005218 316.0
HKD3_k127_6219915_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000004862 220.0
HKD3_k127_6219915_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.00000000000000000000000000000000000000000000000000008018 211.0
HKD3_k127_6219915_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000007177 188.0
HKD3_k127_6219915_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000009216 153.0
HKD3_k127_6219915_6 DAK2 domain fusion protein YloV K07030 - - 0.0000000000000000000000000000000000008951 146.0
HKD3_k127_6219915_7 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000006297 143.0
HKD3_k127_6219915_8 Ribosomal L28 family K02902 - - 0.000000009053 58.0
HKD3_k127_6219915_9 Protein conserved in bacteria - - - 0.0001194 53.0
HKD3_k127_6244031_0 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 448.0
HKD3_k127_6244031_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000001012 119.0
HKD3_k127_6244031_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000008071 55.0
HKD3_k127_6246194_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 358.0
HKD3_k127_6246194_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000005188 73.0
HKD3_k127_6258766_0 dCTP deaminase activity K01494 GO:0003674,GO:0003824,GO:0004170,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0019239,GO:0033973,GO:0047429 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000007042 265.0
HKD3_k127_6258766_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000003401 178.0
HKD3_k127_6258766_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000001036 162.0
HKD3_k127_6258766_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000007921 124.0
HKD3_k127_6262484_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006908 310.0
HKD3_k127_6262484_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007879 271.0
HKD3_k127_6262484_2 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.0000000000000000000004458 105.0
HKD3_k127_6262484_3 heat shock protein binding - - - 0.0000004031 58.0
HKD3_k127_6266984_0 dehydrogenase K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 432.0
HKD3_k127_6266984_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 423.0
HKD3_k127_6266984_2 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006597 321.0
HKD3_k127_6266984_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000001393 197.0
HKD3_k127_627054_0 PFAM RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 377.0
HKD3_k127_627054_1 Catalyzes the reversible retro-aldol cleavage of both 5- keto-4-deoxy-D-glucarate and 2-keto-3-deoxy-D-glucarate to pyruvate and tartronic semialdehyde K01630 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008672,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016830,GO:0016832,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046392,GO:0046395,GO:0071704,GO:1901575 4.1.2.20 0.000000000000000000000000000000000000000000000005028 181.0
HKD3_k127_627054_2 esterase - - - 0.00000000000000000000001017 113.0
HKD3_k127_6292394_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 433.0
HKD3_k127_6292394_1 YCII-related domain - - - 0.0000000000000000000000000000000006399 139.0
HKD3_k127_6292394_2 DNA primase, small subunit K01971 - 6.5.1.1 0.000000000000000000000008328 106.0
HKD3_k127_6342413_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 443.0
HKD3_k127_6342413_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001002 289.0
HKD3_k127_6342413_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000007086 58.0
HKD3_k127_6342413_11 negative regulation of DNA recombination - - - 0.000003143 56.0
HKD3_k127_6342413_12 Asp23 family, cell envelope-related function - - - 0.0001414 53.0
HKD3_k127_6342413_2 PFAM Dak phosphatase K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001969 273.0
HKD3_k127_6342413_3 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000001296 230.0
HKD3_k127_6342413_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000001909 177.0
HKD3_k127_6342413_5 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000008142 162.0
HKD3_k127_6342413_6 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000002702 140.0
HKD3_k127_6342413_7 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000004256 118.0
HKD3_k127_6342413_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000009596 107.0
HKD3_k127_6342413_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001918 85.0
HKD3_k127_6356536_0 Belongs to the cysteine synthase cystathionine beta- synthase family - - - 3.955e-209 662.0
HKD3_k127_6356536_1 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009119,GO:0009163,GO:0009164,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:1901135,GO:1901136,GO:1901137,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008207 526.0
HKD3_k127_6356536_2 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K09065 - 2.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006918 526.0
HKD3_k127_6356536_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 466.0
HKD3_k127_6356536_4 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 401.0
HKD3_k127_6356536_5 Pyridoxal-phosphate dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 399.0
HKD3_k127_6356536_6 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.00000000000000000000000000000000000002757 148.0
HKD3_k127_6441934_0 ATPases associated with a variety of cellular activities K10112,K10195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 453.0
HKD3_k127_6441934_1 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000008662 164.0
HKD3_k127_6441934_2 Tetratricopeptide repeat - - - 0.000000000000007394 83.0
HKD3_k127_6441934_3 Luciferase-like monooxygenase - - - 0.0000003407 57.0
HKD3_k127_6449340_0 Sulfatase K01130 - 3.1.6.1 0.0 1412.0
HKD3_k127_6449340_1 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 597.0
HKD3_k127_6449340_2 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 511.0
HKD3_k127_6449340_3 membrane protein of uknown function UCP014873 - - - 0.000000000000000000000001813 111.0
HKD3_k127_6449340_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000004815 78.0
HKD3_k127_6449340_5 zinc-ribbon family - - - 0.000001187 58.0
HKD3_k127_6449340_6 - - - - 0.0003474 51.0
HKD3_k127_6452307_0 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000002911 134.0
HKD3_k127_6452307_1 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.00000000000000000000000000000004207 130.0
HKD3_k127_6452307_2 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.000000000000000000000000002595 113.0
HKD3_k127_6452307_3 Type II transport protein GspH K08084 - - 0.0000000000000000000001559 114.0
HKD3_k127_6452307_4 Type IV Pilus-assembly protein W K02672 - - 0.00000000000000000009919 103.0
HKD3_k127_6452307_5 type IV pilus modification protein PilV K02671 - - 0.0000000000000002005 91.0
HKD3_k127_6511398_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.0 1015.0
HKD3_k127_6511398_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 456.0
HKD3_k127_6511398_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007293 403.0
HKD3_k127_6511398_3 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005893 314.0
HKD3_k127_6511398_4 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005473 288.0
HKD3_k127_6511398_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000006104 267.0
HKD3_k127_6511398_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000003399 205.0
HKD3_k127_6511398_7 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000008391 141.0
HKD3_k127_6511398_8 PFAM Peptidase family M23 - - - 0.0000006042 60.0
HKD3_k127_65396_0 nitrite reductase [NAD(P)H] activity K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000003955 197.0
HKD3_k127_65396_1 Protein of unknown function (DUF1684) K09164 - - 0.00000000003473 63.0
HKD3_k127_6553651_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 427.0
HKD3_k127_6553651_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000009546 179.0
HKD3_k127_6553651_2 Belongs to the UPF0235 family K09131 - - 0.000001224 59.0
HKD3_k127_6565580_0 Cyclin-dependent kinase inhibitor 3 (CDKN3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000005477 253.0
HKD3_k127_6565580_1 Mannitol dehydrogenase rossman K00040,K00045 - 1.1.1.57,1.1.1.67 0.000000000000000000000000009597 110.0
HKD3_k127_6565580_2 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000002124 85.0
HKD3_k127_6565580_3 domain, Protein - - - 0.00006318 53.0
HKD3_k127_6577583_0 GMC oxidoreductase K00108 - 1.1.99.1 1.007e-297 926.0
HKD3_k127_6577583_1 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004132 276.0
HKD3_k127_6577583_2 YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000000000000000000000000000003129 174.0
HKD3_k127_6577583_4 PFAM Response regulator receiver domain - - - 0.000000000000000007103 85.0
HKD3_k127_6577583_5 Domain of unknown function (DUF4395) - - - 0.00001895 55.0
HKD3_k127_6614247_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 397.0
HKD3_k127_6614247_1 -acetyltransferase - - - 0.000000000000001101 86.0
HKD3_k127_6614247_2 Cupin 2, conserved barrel domain protein - - - 0.000002008 57.0
HKD3_k127_6616146_0 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 531.0
HKD3_k127_6616146_1 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 490.0
HKD3_k127_6616146_2 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 439.0
HKD3_k127_6616146_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 346.0
HKD3_k127_6616146_4 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000006514 205.0
HKD3_k127_6616146_5 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000000000000000001423 129.0
HKD3_k127_6616146_6 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000001569 105.0
HKD3_k127_6616146_7 TPM domain K06872 - - 0.000000006527 69.0
HKD3_k127_6616146_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000002343 56.0
HKD3_k127_6616146_9 Ami_2 K01447,K11062 - 3.5.1.28 0.00000101 61.0
HKD3_k127_6672117_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051537,GO:0051540,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 315.0
HKD3_k127_6672117_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000002268 128.0
HKD3_k127_6710816_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 314.0
HKD3_k127_6710816_1 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001502 272.0
HKD3_k127_6710816_2 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000008004 250.0
HKD3_k127_6710816_3 PFAM class II aldolase adducin family protein K01628,K03077 - 4.1.2.17,5.1.3.4 0.00000000000000000000000000000000001536 148.0
HKD3_k127_6710816_4 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000005432 90.0
HKD3_k127_6710816_5 Bacterial transcription activator, effector binding domain - - - 0.000000001835 71.0
HKD3_k127_6710816_6 Acyl-ACP thioesterase - - - 0.000000004104 69.0
HKD3_k127_6755528_0 isomerase activity - - - 0.0000000000000001309 91.0
HKD3_k127_6755528_1 protein secretion by the type IV secretion system - - - 0.0000000001715 73.0
HKD3_k127_6780627_0 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003095 247.0
HKD3_k127_6780627_1 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.0000000000000000000000000000000000000000000000000000000000000008707 229.0
HKD3_k127_6780627_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000001528 64.0
HKD3_k127_6844155_0 Glycosyl transferase, family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006682 265.0
HKD3_k127_6844155_1 Ferrous iron transport protein B K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007483 258.0
HKD3_k127_6915857_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 421.0
HKD3_k127_6915857_1 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002409 246.0
HKD3_k127_6915857_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000003426 175.0
HKD3_k127_6915857_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.0000000000000000000000000000262 131.0
HKD3_k127_6915857_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000008674 126.0
HKD3_k127_6915857_5 Short C-terminal domain - - - 0.0000000000000002295 87.0
HKD3_k127_6915857_6 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0004131 46.0
HKD3_k127_701981_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000002417 210.0
HKD3_k127_701981_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000002928 123.0
HKD3_k127_7035206_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 289.0
HKD3_k127_7035206_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000004451 143.0
HKD3_k127_7035206_2 Alpha/beta hydrolase family - - - 0.000002807 51.0
HKD3_k127_71544_0 L-phenylalanine transmembrane transporter activity K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 436.0
HKD3_k127_71544_1 Belongs to the binding-protein-dependent transport system permease family K01997,K11956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006934 387.0
HKD3_k127_71544_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999,K07407 - 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 342.0
HKD3_k127_71544_3 branched-chain amino acid transmembrane transporter activity K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 306.0
HKD3_k127_71544_4 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 298.0
HKD3_k127_71544_5 phosphatase K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000695 224.0
HKD3_k127_71544_6 oxidoreductase activity K00059,K18009 - 1.1.1.100,1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000001226 151.0
HKD3_k127_71544_7 Short-chain dehydrogenase reductase sdr K00046 - 1.1.1.69 0.000000000000000000000000000002777 124.0
HKD3_k127_71544_8 EamA-like transporter family - - - 0.00000000000000000003701 102.0
HKD3_k127_71544_9 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000002231 68.0
HKD3_k127_7154936_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1232.0
HKD3_k127_7154936_1 Protein of unknown function (DUF1269) - - - 0.000000000000000000000000000000000000000000000007411 181.0
HKD3_k127_7154936_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001077 172.0
HKD3_k127_7154936_3 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000000000000000001396 113.0
HKD3_k127_72228_0 Catalyzes the coenzyme F420-dependent oxidation of glucose 6-phosphate (G6P) to 6-phosphogluconolactone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 546.0
HKD3_k127_72228_1 TOBE domain K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 410.0
HKD3_k127_72228_2 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009689 257.0
HKD3_k127_72228_3 Binding-protein-dependent transport system inner membrane component K02054 - - 0.00000000000000000000000000000000000000000006915 162.0
HKD3_k127_72228_4 PFAM pyridoxamine 5'-phosphate oxidase-related - - - 0.00000000000001168 76.0
HKD3_k127_7257333_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 296.0
HKD3_k127_7257333_1 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism - - - 0.000000000000007432 77.0
HKD3_k127_7257637_0 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 473.0
HKD3_k127_7257637_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000785 353.0
HKD3_k127_7257637_2 pfam abc1 K03688 - - 0.000000000000000000000000000000000000001562 161.0
HKD3_k127_7284578_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 581.0
HKD3_k127_7284578_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 564.0
HKD3_k127_7284578_10 Haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000048 169.0
HKD3_k127_7284578_11 AI-2E family transporter - - - 0.00000000000000002784 96.0
HKD3_k127_7284578_12 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000001639 72.0
HKD3_k127_7284578_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00596,K00823 - 2.6.1.19,4.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 524.0
HKD3_k127_7284578_3 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 408.0
HKD3_k127_7284578_4 Multicopper oxidase K22348 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 303.0
HKD3_k127_7284578_5 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 289.0
HKD3_k127_7284578_6 PFAM Acetyl-CoA hydrolase transferase K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004931 276.0
HKD3_k127_7284578_7 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006954 281.0
HKD3_k127_7284578_8 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000009925 233.0
HKD3_k127_7284578_9 D-alanyl-D-alanine carboxypeptidase K07260 - 3.4.17.14 0.0000000000000000000000000000000000000000000000000000000000001051 240.0
HKD3_k127_7297117_0 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 347.0
HKD3_k127_7297117_1 Secreted repeat of unknown function - - - 0.0000000000000000000000008028 119.0
HKD3_k127_7297117_2 GCN5-related N-acetyl-transferase K06975 - - 0.000000000000000000000001108 111.0
HKD3_k127_7297117_3 Hydrolase of the alpha beta-hydrolase K07020 - - 0.0000000000000000001983 96.0
HKD3_k127_7297117_4 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000001547 93.0
HKD3_k127_7297117_5 ABC-2 family transporter protein K01992 - - 0.00003554 49.0
HKD3_k127_7302397_0 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 427.0
HKD3_k127_7302397_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 334.0
HKD3_k127_7302397_10 AAA domain - - - 0.000000000000000000000004535 119.0
HKD3_k127_7302397_2 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000002437 236.0
HKD3_k127_7302397_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000003582 220.0
HKD3_k127_7302397_4 pyridoxamine 5'-phosphate K07005 - - 0.0000000000000000000000000000000000000002241 167.0
HKD3_k127_7302397_5 PFAM Metallophosphoesterase K01090 - 3.1.3.16 0.000000000000000000000000000000000000003318 164.0
HKD3_k127_7302397_6 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000762 140.0
HKD3_k127_7302397_7 Peptidase family S51 - - - 0.0000000000000000000000000000000004242 140.0
HKD3_k127_7302397_8 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.00000000000000000000000000000003962 141.0
HKD3_k127_7302397_9 Probable zinc-ribbon domain - - - 0.000000000000000000000000002339 120.0
HKD3_k127_7315159_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 7.229e-230 735.0
HKD3_k127_7315159_1 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 532.0
HKD3_k127_7315159_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000002681 252.0
HKD3_k127_7315159_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000007439 218.0
HKD3_k127_7315159_4 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000003129 201.0
HKD3_k127_7315159_5 F420-dependent oxidoreductase, Rv1855c family - - - 0.00000000000000000000000000000000131 151.0
HKD3_k127_7317007_0 Belongs to the proline racemase family K01777,K12658 - 5.1.1.4,5.1.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 533.0
HKD3_k127_7317007_1 urease activity K01427 GO:0003674,GO:0003824,GO:0006807,GO:0008150,GO:0008152,GO:0009039,GO:0009056,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019627,GO:0034641,GO:0043419,GO:0043603,GO:0043605,GO:0044237,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0071704,GO:0071941,GO:1901564,GO:1901565,GO:1901575 3.5.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 536.0
HKD3_k127_7317007_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000001111 289.0
HKD3_k127_7317007_3 ATPases associated with a variety of cellular activities K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009646 277.0
HKD3_k127_7317007_4 PFAM galactose-1-phosphate uridyl transferase domain protein K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000137 249.0
HKD3_k127_7317007_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000000000002443 192.0
HKD3_k127_7317007_6 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.000000000000000000000000000000000000000404 161.0
HKD3_k127_7317007_7 belongs to the urease gamma subunit family K14048 - 3.5.1.5 0.0000000000000000000000003438 111.0
HKD3_k127_7317007_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07651 - 2.7.13.3 0.00000000000000000002236 92.0
HKD3_k127_7317007_9 Acetyltransferase (GNAT) family - - - 0.00000000145 64.0
HKD3_k127_7317081_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000004683 233.0
HKD3_k127_7317081_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K13019 - 5.1.3.23 0.00000000000000000000000000000000000000000008983 169.0
HKD3_k127_7317081_2 Glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000001075 176.0
HKD3_k127_7317081_3 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000009243 163.0
HKD3_k127_7317081_4 Glycosyl transferase 4-like - - - 0.000000002345 71.0
HKD3_k127_7329270_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.168e-268 874.0
HKD3_k127_7329270_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000003064 233.0
HKD3_k127_7329270_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000001653 174.0
HKD3_k127_7329270_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000001039 141.0
HKD3_k127_7331007_0 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 500.0
HKD3_k127_7344145_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 0.0 1421.0
HKD3_k127_7354651_0 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000008081 160.0
HKD3_k127_7354651_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000001175 164.0
HKD3_k127_7354651_2 peptidase C26 K01658,K07010 - 4.1.3.27 0.00000000000000000000000000000004986 137.0
HKD3_k127_7354651_3 Peptidoglycan-binding LysM K08259 - 3.4.24.75 0.000000001052 71.0
HKD3_k127_7371498_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.001e-217 690.0
HKD3_k127_7371498_1 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001006 278.0
HKD3_k127_7371498_2 Belongs to the carbohydrate kinase PfkB family - - - 0.00000000000000000000000000000000005973 147.0
HKD3_k127_7371498_3 EamA-like transporter family - - - 0.0000000000000000000001295 110.0
HKD3_k127_7371498_5 HAD-superfamily hydrolase, subfamily IB, PSPase-like K08966 - 3.1.3.87 0.00000007443 57.0
HKD3_k127_7377979_0 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000005542 278.0
HKD3_k127_7377979_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000004081 221.0
HKD3_k127_7377979_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000306 130.0
HKD3_k127_7377979_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000003075 128.0
HKD3_k127_7377979_4 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009902 70.0
HKD3_k127_7380885_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 387.0
HKD3_k127_7380885_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02033,K12369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 361.0
HKD3_k127_7380885_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008277 374.0
HKD3_k127_7380885_3 ABC transporter K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 361.0
HKD3_k127_7380885_4 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 332.0
HKD3_k127_7380885_5 PFAM peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000007041 233.0
HKD3_k127_7380885_6 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000607 207.0
HKD3_k127_7383985_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 428.0
HKD3_k127_7383985_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000003637 185.0
HKD3_k127_7383985_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000001711 148.0
HKD3_k127_7401790_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 601.0
HKD3_k127_7401790_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 385.0
HKD3_k127_7401790_10 PFAM GDSL-like Lipase Acylhydrolase - - - 0.00000000000000000000000000000000002862 148.0
HKD3_k127_7401790_11 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000002959 156.0
HKD3_k127_7401790_12 ribosomal protein l17 K02879 - - 0.00000000000000000000000000001203 123.0
HKD3_k127_7401790_13 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000001231 129.0
HKD3_k127_7401790_14 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000003538 119.0
HKD3_k127_7401790_15 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000001552 109.0
HKD3_k127_7401790_16 YbbR-like protein - GO:0008150,GO:0031279,GO:0031281,GO:0043085,GO:0044093,GO:0045761,GO:0045762,GO:0050790,GO:0051339,GO:0051349,GO:0065007,GO:0065009 - 0.0000000000000002265 93.0
HKD3_k127_7401790_17 PFAM Peptidase M22, glycoprotease K14742 GO:0002949,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0071944,GO:0090304,GO:1901360 - 0.00000000000004167 81.0
HKD3_k127_7401790_18 Carbohydrate kinase - - - 0.00000002049 67.0
HKD3_k127_7401790_19 Tetratricopeptide TPR_2 repeat protein - - - 0.00000728 58.0
HKD3_k127_7401790_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 361.0
HKD3_k127_7401790_20 - - - - 0.00002937 50.0
HKD3_k127_7401790_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000003969 235.0
HKD3_k127_7401790_4 DisA bacterial checkpoint controller nucleotide-binding K18672 GO:0003674,GO:0003824,GO:0004016,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009975,GO:0016020,GO:0016021,GO:0016829,GO:0016849,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 2.7.7.85 0.00000000000000000000000000000000000000000000000000000001491 210.0
HKD3_k127_7401790_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000005637 202.0
HKD3_k127_7401790_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000009194 214.0
HKD3_k127_7401790_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000001068 183.0
HKD3_k127_7401790_8 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000007036 171.0
HKD3_k127_7401790_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000007758 175.0
HKD3_k127_7408879_0 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 366.0
HKD3_k127_7408879_1 PFAM amidohydrolase K01464,K01466 - 3.5.2.2,3.5.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 356.0
HKD3_k127_7408879_2 PFAM Phosphatidylinositol 3- and 4-kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 292.0
HKD3_k127_7408879_3 Dihydrodipicolinate synthetase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003327 268.0
HKD3_k127_7408879_4 Protein of unknown function (DUF3090) - - - 0.00000000000000000000000000000000000000000000000000000005613 201.0
HKD3_k127_7408879_5 COG1070 Sugar (pentulose and hexulose) kinases K00854 - 2.7.1.17 0.0000000000000000000000000000000000000548 144.0
HKD3_k127_7408879_6 AroM protein - - - 0.00000000000000001741 91.0
HKD3_k127_7415387_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 329.0
HKD3_k127_7415387_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000006167 224.0
HKD3_k127_7415387_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002668 204.0
HKD3_k127_7415387_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000009863 173.0
HKD3_k127_7416881_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 571.0
HKD3_k127_7416881_1 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000415 288.0
HKD3_k127_7416881_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000001672 134.0
HKD3_k127_7419296_0 Carboxylate--amine ligase - - - 0.0000000000000000000000000000000000000000002608 169.0
HKD3_k127_7419296_1 tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity - - - 0.0000000000000000000000000000000000002771 158.0
HKD3_k127_7419296_2 -acetyltransferase - - - 0.000000000000000000000000000002638 139.0
HKD3_k127_7419296_3 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.000000000000000000000001475 121.0
HKD3_k127_7419296_4 YwiC-like protein - - - 0.0000000000000000000007315 105.0
HKD3_k127_7419296_5 - - - - 0.0000000000000000004173 92.0
HKD3_k127_7419296_6 - - - - 0.000000000001109 73.0
HKD3_k127_7419296_7 Flagellar Assembly Protein A K09749 - - 0.00000134 62.0
HKD3_k127_7419296_8 amine oxidase K09879 - - 0.00001501 57.0
HKD3_k127_7419296_9 PFAM pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0004124 52.0
HKD3_k127_7426124_0 Bacterial extracellular solute-binding protein K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000003594 250.0
HKD3_k127_7426124_1 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.00000000000000000000000000000000000000000000000000000000000009423 237.0
HKD3_k127_7426124_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000006794 154.0
HKD3_k127_7428140_0 ABC transporter, transmembrane region K06147 - - 1.659e-220 694.0
HKD3_k127_7437607_0 belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000004947 130.0
HKD3_k127_7437607_1 Zincin-like metallopeptidase - - - 0.00000000000000000000000000004595 121.0
HKD3_k127_7437607_2 DNA-binding transcription factor activity K03892 - - 0.00000000000000001709 85.0
HKD3_k127_7437607_3 Cobalamin B12-binding domain - - - 0.0000000000000007772 87.0
HKD3_k127_7437607_4 carboxylic ester hydrolase activity - - - 0.0000000000000008082 89.0
HKD3_k127_7437607_5 Histone deacetylase domain - - - 0.0000000002422 65.0
HKD3_k127_7437607_6 Wyosine base formation K21167 - - 0.0001588 51.0
HKD3_k127_7448253_0 tRNA synthetases class II (D, K and N) K09759 - 6.1.1.23 2.36e-234 732.0
HKD3_k127_7448253_1 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 387.0
HKD3_k127_7448253_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 379.0
HKD3_k127_7448253_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000001641 188.0
HKD3_k127_7448253_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000003209 196.0
HKD3_k127_7448253_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000001556 149.0
HKD3_k127_7452525_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000001055 123.0
HKD3_k127_7459990_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 632.0
HKD3_k127_7459990_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 482.0
HKD3_k127_7459990_10 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000002959 241.0
HKD3_k127_7459990_11 L-asparaginase II - - - 0.000000000000000000000000000000000000000000000000000000331 209.0
HKD3_k127_7459990_12 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000002317 196.0
HKD3_k127_7459990_13 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000000007788 211.0
HKD3_k127_7459990_14 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000003736 160.0
HKD3_k127_7459990_15 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000007475 148.0
HKD3_k127_7459990_16 coenzyme F420 binding - - - 0.000000000000000000000000000000000001115 154.0
HKD3_k127_7459990_17 DinB superfamily - - - 0.000000000000000000000000000000000007011 158.0
HKD3_k127_7459990_18 domain protein K03709 - - 0.00000000000000000000000000000004984 144.0
HKD3_k127_7459990_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 441.0
HKD3_k127_7459990_20 - - - - 0.0000000000000000000000000006457 124.0
HKD3_k127_7459990_21 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000249 122.0
HKD3_k127_7459990_22 heat shock protein binding K03686,K05516 - - 0.000000000132 74.0
HKD3_k127_7459990_3 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009025 438.0
HKD3_k127_7459990_4 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 404.0
HKD3_k127_7459990_5 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 380.0
HKD3_k127_7459990_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03851 - 2.6.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007491 355.0
HKD3_k127_7459990_7 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 344.0
HKD3_k127_7459990_8 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000744 284.0
HKD3_k127_7459990_9 response regulator K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001289 266.0
HKD3_k127_7463628_0 Pfam:DUF2029 - - - 0.000000000000000000000000000000000003713 154.0
HKD3_k127_7463628_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000006043 127.0
HKD3_k127_7463628_2 - - - - 0.00000000000000000000002093 102.0
HKD3_k127_7463628_3 F420-dependent oxidoreductase - - - 0.000000000000000001125 91.0
HKD3_k127_7497093_0 ABC transporter K05847 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 363.0
HKD3_k127_7497093_1 Oxidoreductase molybdopterin binding domain K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001656 278.0
HKD3_k127_7497093_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003566 293.0
HKD3_k127_7497093_3 F420-dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000009849 203.0
HKD3_k127_7497093_4 Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000000001328 201.0
HKD3_k127_7497093_5 Binding-protein-dependent transport system inner membrane component K05846 - - 0.000000000000000000000000000000000000000000000002091 196.0
HKD3_k127_7497093_6 Substrate binding domain of ABC-type glycine betaine transport system K05845 - - 0.000000000000000000000000000000000000000002601 167.0
HKD3_k127_7497093_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000001725 124.0
HKD3_k127_7497093_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000005211 107.0
HKD3_k127_7497093_9 helix_turn_helix, Lux Regulon - - - 0.00000001568 66.0
HKD3_k127_7499192_0 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002652 230.0
HKD3_k127_7501598_0 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001714 288.0
HKD3_k127_7501598_1 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000006354 230.0
HKD3_k127_7501598_2 Ketopantoate reductase - - - 0.00000000000000000000000000000000000000000000000002041 198.0
HKD3_k127_7501598_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000006869 134.0
HKD3_k127_7513373_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000001104 95.0
HKD3_k127_7513373_1 VIT family - - - 0.0000000000000003663 81.0
HKD3_k127_7513373_2 Benzene 1,2-dioxygenase K05710 - - 0.000000000000001327 79.0
HKD3_k127_7516298_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 583.0
HKD3_k127_7516298_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 414.0
HKD3_k127_7516298_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 349.0
HKD3_k127_7516298_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 312.0
HKD3_k127_7516298_4 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 313.0
HKD3_k127_7516298_5 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.00000000000000000000000000000000000000000000000000000000000007243 238.0
HKD3_k127_7516298_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000362 204.0
HKD3_k127_7516298_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000002654 70.0
HKD3_k127_7527475_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 598.0
HKD3_k127_7527475_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 367.0
HKD3_k127_7527475_2 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01758,K01761 - 4.4.1.1,4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000007928 223.0
HKD3_k127_7527475_3 ResB-like family - - - 0.0000000000000000000000000000000000000000000000001689 195.0
HKD3_k127_7527475_5 COG0477 Permeases of the major facilitator superfamily - - - 0.000000003605 69.0
HKD3_k127_7527475_6 PucR C-terminal helix-turn-helix domain - - - 0.00000001327 67.0
HKD3_k127_755818_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 5.944e-305 951.0
HKD3_k127_755818_1 PFAM Glucose Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 390.0
HKD3_k127_755818_2 Iron permease FTR1 K07243 - - 0.000000000000000000000000000000000000000000000000000000007458 210.0
HKD3_k127_755818_3 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000001485 195.0
HKD3_k127_755818_4 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000004192 171.0
HKD3_k127_755818_5 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000544 174.0
HKD3_k127_755818_6 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000001357 175.0
HKD3_k127_755818_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000007325 149.0
HKD3_k127_755818_8 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000000000000000000000005428 127.0
HKD3_k127_755818_9 Cupin domain - - - 0.0000000000000000000000002253 123.0
HKD3_k127_7591001_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 518.0
HKD3_k127_7591001_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000003622 195.0
HKD3_k127_7591001_2 aminotransferase class I and II K10907 - - 0.000000000000000000000000000000000000000000000001528 178.0
HKD3_k127_7591001_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000001393 96.0
HKD3_k127_7659903_0 NMT1/THI5 like K15598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 332.0
HKD3_k127_7659903_1 ABC transporter (permease) K15599 - - 0.000000000000000000000000000000324 140.0
HKD3_k127_7659903_2 beta-lactamase domain protein - - - 0.000000004474 59.0
HKD3_k127_7667021_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.514e-207 661.0
HKD3_k127_7667021_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000382 216.0
HKD3_k127_7667021_2 DHHA1 domain K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000005596 182.0
HKD3_k127_7667021_3 Riboflavin kinase K11753 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008531,GO:0009058,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009124,GO:0009156,GO:0009161,GO:0009165,GO:0009231,GO:0009259,GO:0009260,GO:0009398,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019866,GO:0031090,GO:0031966,GO:0031967,GO:0031975,GO:0034641,GO:0034654,GO:0042364,GO:0042726,GO:0042727,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046390,GO:0046444,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.26,2.7.7.2 0.000000000000000000000000008232 121.0
HKD3_k127_7667021_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000001131 118.0
HKD3_k127_7680447_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 381.0
HKD3_k127_7680447_1 CBS domain containing protein K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000009682 262.0
HKD3_k127_7680447_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000007339 218.0
HKD3_k127_7680447_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000006215 171.0
HKD3_k127_7680447_4 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000001798 156.0
HKD3_k127_7680447_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000002214 155.0
HKD3_k127_7680447_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000002105 89.0
HKD3_k127_7685475_0 -acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 316.0
HKD3_k127_7685475_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 296.0
HKD3_k127_7685475_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000215 255.0
HKD3_k127_7685475_3 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000003778 58.0
HKD3_k127_7709816_0 Evidence 5 No homology to any previously reported sequences - - - 5.157e-272 869.0
HKD3_k127_7709816_1 alcohol dehydrogenase K00008,K08322 - 1.1.1.14,1.1.1.380 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008431 531.0
HKD3_k127_7709816_2 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 477.0
HKD3_k127_7709816_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 435.0
HKD3_k127_7709816_4 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 398.0
HKD3_k127_7709816_5 Transcriptional regulator K22293 - - 0.0000000000000000000000000000000000000000000000000000000000000002288 231.0
HKD3_k127_7709816_7 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000005156 184.0
HKD3_k127_7709816_8 Psort location Cytoplasmic, score K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000001598 184.0
HKD3_k127_7709816_9 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.000000000001212 68.0
HKD3_k127_7712676_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane - - - 0.0 1153.0
HKD3_k127_7712676_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 380.0
HKD3_k127_7712676_2 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004903 249.0
HKD3_k127_7712676_3 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001487 254.0
HKD3_k127_7747111_0 Protein of unknown function (DUF1211) - - - 0.0000000000000000000000000000000000000000000000002058 186.0
HKD3_k127_7747111_2 Protein of unknown function (DUF1269) - - - 0.0000000000000000000000000001091 126.0
HKD3_k127_7747111_3 - - - - 0.0001125 48.0
HKD3_k127_7768265_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 488.0
HKD3_k127_7768265_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000009303 262.0
HKD3_k127_7768265_2 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000005979 173.0
HKD3_k127_7768265_3 Cbs domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000006937 140.0
HKD3_k127_7792281_0 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 431.0
HKD3_k127_7792281_1 Pfam:DUF385 - - - 0.0000000000000000000000000000000000000002667 158.0
HKD3_k127_7831852_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1166.0
HKD3_k127_7831852_1 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000001707 160.0
HKD3_k127_7831852_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000001114 150.0
HKD3_k127_7831852_3 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000001392 136.0
HKD3_k127_7855616_0 Glyco_18 K01448,K07260,K20276 - 3.4.17.14,3.5.1.28 0.00000000000000000000000000000004324 147.0
HKD3_k127_7855616_1 ompA family - - - 0.0000000000000000000000317 117.0
HKD3_k127_7863481_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000002516 128.0
HKD3_k127_7863481_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000004182 114.0
HKD3_k127_7863481_2 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000003483 110.0
HKD3_k127_7863481_3 Dienelactone hydrolase family K01061 - 3.1.1.45 0.00006371 46.0
HKD3_k127_787054_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000001575 134.0
HKD3_k127_787054_1 Surface antigen K07277 - - 0.00000000000000000000000000008419 134.0
HKD3_k127_7876099_0 Binding-protein-dependent transport system inner membrane component K02001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 601.0
HKD3_k127_7876099_1 ATPases associated with a variety of cellular activities K02000 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 491.0
HKD3_k127_7876099_10 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000925 181.0
HKD3_k127_7876099_11 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000002698 172.0
HKD3_k127_7876099_12 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000002177 173.0
HKD3_k127_7876099_13 helix_turn_helix isocitrate lyase regulation - - - 0.00000000000000000000000000000000000000009737 162.0
HKD3_k127_7876099_14 cell redox homeostasis K02199 - - 0.0000000000000000000000000000000000000003104 163.0
HKD3_k127_7876099_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000005053 98.0
HKD3_k127_7876099_16 FCD domain - - - 0.0007044 46.0
HKD3_k127_7876099_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 438.0
HKD3_k127_7876099_3 glycine betaine transport K02002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 385.0
HKD3_k127_7876099_4 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 376.0
HKD3_k127_7876099_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006809 353.0
HKD3_k127_7876099_6 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 331.0
HKD3_k127_7876099_7 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007693 288.0
HKD3_k127_7876099_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000001792 228.0
HKD3_k127_7876099_9 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000005227 205.0
HKD3_k127_7895916_0 Family 4 glycosyl hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 406.0
HKD3_k127_7895916_1 ABC transporter (Permease) K10118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 345.0
HKD3_k127_7895916_2 Sugar ABC transporter substrate-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 328.0
HKD3_k127_7895916_3 Binding-protein-dependent transport system inner membrane component K10119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 311.0
HKD3_k127_7895916_4 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000706 227.0
HKD3_k127_7895916_5 Carbohydrate kinase - - - 0.000000000000000000000000000000000000002427 163.0
HKD3_k127_7895916_6 esterase - - - 0.00000000000000000000000000000000000001532 145.0
HKD3_k127_7895916_7 UTRA K03710 - - 0.000000000000000000000000000000002488 139.0
HKD3_k127_7895916_8 YCII-related domain - - - 0.00000000000000000006274 96.0
HKD3_k127_7895916_9 Family 4 glycosyl hydrolase - - - 0.000000000001637 68.0
HKD3_k127_792237_0 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000004858 156.0
HKD3_k127_792237_1 Glutaredoxin-like domain (DUF836) - - - 0.000002193 56.0
HKD3_k127_8017810_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000513 236.0
HKD3_k127_8017810_1 Superoxide dismutase K00518 - 1.15.1.1 0.000000000000000000000000000004554 125.0
HKD3_k127_8017810_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000009865 63.0
HKD3_k127_8060219_0 Phage integrase family K04763 GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000001314 249.0
HKD3_k127_8060219_1 Peptidase M50 - - - 0.00000000000000000000000000000000000000002429 160.0
HKD3_k127_8060219_2 PFAM membrane-flanked domain - - - 0.000000000000000000000000000005492 136.0
HKD3_k127_8060219_3 mRNA catabolic process - - - 0.00000005952 65.0
HKD3_k127_8101922_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003794 294.0
HKD3_k127_8101922_1 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation - - - 0.000000057 64.0
HKD3_k127_8134670_0 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 600.0
HKD3_k127_8134670_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000002477 247.0
HKD3_k127_8134670_2 ACT domain protein - - - 0.0000009537 55.0
HKD3_k127_8134670_3 Pfam:DUF385 - - - 0.000003026 57.0
HKD3_k127_8150146_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000001212 199.0
HKD3_k127_8150146_1 PucR C-terminal helix-turn-helix domain - - - 0.0000000000000005292 92.0
HKD3_k127_8202354_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008044 558.0
HKD3_k127_8202354_1 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000001174 171.0
HKD3_k127_8202354_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000007724 155.0
HKD3_k127_8202354_3 - - - - 0.0001125 48.0
HKD3_k127_8209077_0 Conserved repeat domain - - - 5.53e-250 803.0
HKD3_k127_8341694_0 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 360.0
HKD3_k127_8341694_1 Ion channel K10716 - - 0.0000000000000000000000000000004349 130.0
HKD3_k127_8341694_2 beta-lactamase domain protein K00784 - 3.1.26.11 0.0000000000000006043 85.0
HKD3_k127_8488242_0 NADH-quinone oxidoreductase chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 567.0
HKD3_k127_8488242_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 486.0
HKD3_k127_8488242_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000002581 97.0
HKD3_k127_8488242_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000004473 101.0
HKD3_k127_8488242_12 DNA-binding transcription factor activity K03892 - - 0.00000000000008009 76.0
HKD3_k127_8488242_13 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000008033 55.0
HKD3_k127_8488242_2 Peptidase S9 prolyl oligopeptidase active site domain protein K01303 - 3.4.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 442.0
HKD3_k127_8488242_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 373.0
HKD3_k127_8488242_4 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000003406 208.0
HKD3_k127_8488242_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000002494 188.0
HKD3_k127_8488242_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000000000000000001025 124.0
HKD3_k127_8488242_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000008092 119.0
HKD3_k127_8488242_8 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.000000000000000000000004241 109.0
HKD3_k127_8488242_9 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000001019 107.0
HKD3_k127_8500867_0 PFAM oxidoreductase molybdopterin binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 419.0
HKD3_k127_8500867_1 permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 343.0
HKD3_k127_8500867_2 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - 0.0000000000000000000000000000000000000000000000000001041 200.0
HKD3_k127_8500867_3 Protein of unknown function (DUF998) - - - 0.000000000000000000000000000000000000000000006958 171.0
HKD3_k127_8500867_4 Domain of unknown function (DU1801) - - - 0.0000000000000008844 82.0
HKD3_k127_8500867_5 - - - - 0.00002464 52.0
HKD3_k127_8514297_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004966 504.0
HKD3_k127_8514297_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 376.0
HKD3_k127_8514297_2 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000004176 154.0
HKD3_k127_8514297_3 SMART helix-turn-helix domain protein - - - 0.00000000000000000414 98.0
HKD3_k127_8514297_4 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000004303 67.0
HKD3_k127_8527084_0 ATP dependent DNA ligase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 542.0
HKD3_k127_8527084_2 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000006994 165.0
HKD3_k127_8533591_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 3.083e-206 682.0
HKD3_k127_8533591_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 578.0
HKD3_k127_8533591_10 Double zinc ribbon - - - 0.00000000000000000000004484 112.0
HKD3_k127_8533591_11 diguanylate cyclase - - - 0.000000000000000000001166 108.0
HKD3_k127_8533591_12 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000002895 100.0
HKD3_k127_8533591_13 nUDIX hydrolase K01515,K08310 - 3.6.1.13,3.6.1.67 0.00000000000000000184 98.0
HKD3_k127_8533591_14 CAAX protease self-immunity K07052 - - 0.0000003881 62.0
HKD3_k127_8533591_2 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 451.0
HKD3_k127_8533591_3 IMP dehydrogenase GMP reductase K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 404.0
HKD3_k127_8533591_4 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 389.0
HKD3_k127_8533591_5 PFAM DNA repair protein RadC K03630 - - 0.000000000000000000000000000000000000000000000000000000000004816 219.0
HKD3_k127_8533591_6 iron-sulfur cluster assembly K07400,K13628 - - 0.00000000000000000000000000000000000000000001517 178.0
HKD3_k127_8533591_7 PFAM globin K06886 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0015669,GO:0015671,GO:0015893,GO:0016020,GO:0019825,GO:0020037,GO:0036094,GO:0042221,GO:0042493,GO:0044464,GO:0046906,GO:0048037,GO:0050896,GO:0051179,GO:0051234,GO:0071944,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000001954 157.0
HKD3_k127_8533591_8 Cyclic-di-AMP receptor - - - 0.00000000000000000000000000000263 138.0
HKD3_k127_8533591_9 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000002538 115.0
HKD3_k127_8536528_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1041.0
HKD3_k127_8536528_1 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 433.0
HKD3_k127_8536528_10 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 294.0
HKD3_k127_8536528_11 pfkB family carbohydrate kinase K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001131 280.0
HKD3_k127_8536528_12 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008825 259.0
HKD3_k127_8536528_13 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000003393 154.0
HKD3_k127_8536528_14 Oxidoreductase FAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000003991 135.0
HKD3_k127_8536528_15 Belongs to the peptidase S51 family - - - 0.00000000000000000000000000005272 121.0
HKD3_k127_8536528_16 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000003398 79.0
HKD3_k127_8536528_2 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004864 449.0
HKD3_k127_8536528_3 Zinc-binding dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 368.0
HKD3_k127_8536528_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 368.0
HKD3_k127_8536528_5 PFAM Binding-protein-dependent transport K02025,K10228 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 322.0
HKD3_k127_8536528_6 alcohol dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 320.0
HKD3_k127_8536528_7 Zinc-binding dehydrogenase K00121 - 1.1.1.1,1.1.1.284 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 325.0
HKD3_k127_8536528_8 helix_turn _helix lactose operon repressor K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 312.0
HKD3_k127_8536528_9 ABC-type sugar transport system, permease component K10229 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004254 307.0
HKD3_k127_8550706_0 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 469.0
HKD3_k127_8550706_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 303.0
HKD3_k127_8550706_2 Choline/ethanolamine kinase - - - 0.0000002325 64.0
HKD3_k127_8568216_0 FeS assembly protein SufB K09014 - - 4.114e-222 696.0
HKD3_k127_8568216_1 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000007837 197.0
HKD3_k127_8568216_2 exo-alpha-(2->6)-sialidase activity - - - 0.000003572 59.0
HKD3_k127_8572320_0 LysE type translocator - - - 0.000000000000000000000000000001751 138.0
HKD3_k127_8572320_1 NUDIX domain - - - 0.00000000000000000001348 94.0
HKD3_k127_8572320_2 PFAM Major Facilitator Superfamily - - - 0.0000000000002188 81.0
HKD3_k127_8572320_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000005413 55.0
HKD3_k127_8577078_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 309.0
HKD3_k127_8577078_1 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 310.0
HKD3_k127_8577078_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000011 284.0
HKD3_k127_8577078_3 - - - - 0.0000000000000000000000000000000000000000002498 173.0
HKD3_k127_8577078_4 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000002576 150.0
HKD3_k127_8603934_0 Flavin containing amine oxidoreductase K06954 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 364.0
HKD3_k127_8603934_1 Protein of unknown function (DUF1365) K09701 - - 0.00000000000000000000000000000000000000004726 173.0
HKD3_k127_8603934_2 Polyketide cyclase - - - 0.00000000000000000003213 98.0
HKD3_k127_8603934_3 NAD dependent epimerase/dehydratase family - - - 0.0000000000000008231 86.0
HKD3_k127_8604984_0 CoA-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 387.0
HKD3_k127_8604984_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006956 264.0
HKD3_k127_8604984_2 N-acetylglucosaminylinositol deacetylase activity K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000003038 241.0
HKD3_k127_8604984_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000003878 237.0
HKD3_k127_8604984_4 protein flavinylation K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000004901 210.0
HKD3_k127_8604984_5 Ferric reductase like transmembrane component K17247 - - 0.000000000000000000000000000000008563 139.0
HKD3_k127_86145_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 358.0
HKD3_k127_86145_1 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658,K09699 - 2.3.1.12,2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 343.0
HKD3_k127_86145_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 GO:0003674,GO:0003824,GO:0004000,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006144,GO:0006152,GO:0006154,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009113,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009156,GO:0009161,GO:0009163,GO:0009164,GO:0009165,GO:0009167,GO:0009168,GO:0009987,GO:0015949,GO:0015950,GO:0016787,GO:0016810,GO:0016814,GO:0017144,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0032261,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042278,GO:0042440,GO:0042451,GO:0042454,GO:0042455,GO:0042737,GO:0043094,GO:0043096,GO:0043101,GO:0043103,GO:0043173,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046085,GO:0046100,GO:0046101,GO:0046102,GO:0046103,GO:0046112,GO:0046128,GO:0046129,GO:0046130,GO:0046148,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072523,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901657,GO:1901658,GO:1901659 3.5.4.4 0.00000000000000000000000000000000000000000000000000000000000000003546 229.0
HKD3_k127_86145_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000471 199.0
HKD3_k127_86145_4 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000001624 164.0
HKD3_k127_861550_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 615.0
HKD3_k127_861550_1 Belongs to the peptidase S8 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 587.0
HKD3_k127_861550_10 NlpC/P60 family - - - 0.000000000000000000000000000000000000000000008736 168.0
HKD3_k127_861550_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000002778 147.0
HKD3_k127_861550_12 Copper binding proteins, plastocyanin/azurin family - - - 0.00000000000000000000008827 102.0
HKD3_k127_861550_13 - - - - 0.0000000000000000002139 93.0
HKD3_k127_861550_14 Secreted repeat of unknown function - - - 0.0000000000000000747 93.0
HKD3_k127_861550_15 Putative auto-transporter adhesin, head GIN domain - - - 0.00000000000004418 80.0
HKD3_k127_861550_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 442.0
HKD3_k127_861550_3 Acyl-CoA dehydrogenase, N-terminal domain K00248,K00249 - 1.3.8.1,1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 375.0
HKD3_k127_861550_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 373.0
HKD3_k127_861550_5 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000139 275.0
HKD3_k127_861550_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000005044 231.0
HKD3_k127_861550_7 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000002215 216.0
HKD3_k127_861550_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000912 218.0
HKD3_k127_861550_9 - - - - 0.000000000000000000000000000000000000000000000006497 189.0
HKD3_k127_8640779_0 Domain of unknown function (DUF1727) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 408.0
HKD3_k127_8640779_1 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 323.0
HKD3_k127_8640779_2 PFAM CobB CobQ domain protein glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002476 276.0
HKD3_k127_8640779_3 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000006464 223.0
HKD3_k127_8652434_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 541.0
HKD3_k127_86526_0 NAD synthase K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000005827 278.0
HKD3_k127_86526_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009993 257.0
HKD3_k127_8655494_0 denitrification pathway K02569,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 451.0
HKD3_k127_8655494_1 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 395.0
HKD3_k127_8655494_10 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000002867 151.0
HKD3_k127_8655494_11 recombinase activity K07450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000001447 136.0
HKD3_k127_8655494_12 Protein of unknown function with PCYCGC motif - - - 0.00000000000003998 81.0
HKD3_k127_8655494_2 ResB-like family K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 399.0
HKD3_k127_8655494_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 375.0
HKD3_k127_8655494_4 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 366.0
HKD3_k127_8655494_5 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 331.0
HKD3_k127_8655494_6 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000153 256.0
HKD3_k127_8655494_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0040007,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000003681 263.0
HKD3_k127_8655494_8 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000002812 184.0
HKD3_k127_8655494_9 cytochrome complex assembly - - - 0.00000000000000000000000000000000000004908 157.0
HKD3_k127_8659645_0 F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002215 276.0
HKD3_k127_8659645_1 transmembrane transport K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000005407 232.0
HKD3_k127_8659645_10 Bacterial protein of unknown function (DUF881) - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000001351 104.0
HKD3_k127_8659645_11 Domain of unknown function (DU1801) - - - 0.0000000000000000007795 98.0
HKD3_k127_8659645_12 Bacterial protein of unknown function (DUF951) - - - 0.000000000000000004418 86.0
HKD3_k127_8659645_13 cysteine-tRNA ligase activity - - - 0.000003145 59.0
HKD3_k127_8659645_14 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16,6.3.1.13 0.000119 54.0
HKD3_k127_8659645_2 Peptidase A4 family - - - 0.000000000000000000000000000000000000000000000000002545 194.0
HKD3_k127_8659645_3 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000003267 167.0
HKD3_k127_8659645_4 acetyltransferase - - - 0.000000000000000000000000000000000000000002859 168.0
HKD3_k127_8659645_5 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000007832 171.0
HKD3_k127_8659645_6 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000007238 154.0
HKD3_k127_8659645_7 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000008337 139.0
HKD3_k127_8659645_8 Peptidase MA superfamily - - - 0.000000000000000000000001023 122.0
HKD3_k127_8659645_9 Bacterial protein of unknown function (DUF881) - - - 0.0000000000000000000000589 113.0
HKD3_k127_8659761_0 Bacterial DNA topoisomeraes I ATP-binding domain K03168 - 5.99.1.2 7.655e-202 656.0
HKD3_k127_8659761_1 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 420.0
HKD3_k127_8659761_10 phosphoesterase (MutT family) - - - 0.000000000000000000000000001658 116.0
HKD3_k127_8659761_11 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009259,GO:0009260,GO:0009267,GO:0009405,GO:0009605,GO:0009987,GO:0009991,GO:0015968,GO:0015969,GO:0015970,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030145,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034035,GO:0034036,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0042578,GO:0042594,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044419,GO:0044464,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051704,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.6.5,3.1.7.2 0.0000000000000000000000001323 124.0
HKD3_k127_8659761_12 FemAB family K05363,K11693 - 2.3.2.10,2.3.2.16 0.00000000000000000006324 104.0
HKD3_k127_8659761_13 Bacterial Ig-like domain - - - 0.000000000005569 79.0
HKD3_k127_8659761_14 - - - - 0.0001036 50.0
HKD3_k127_8659761_15 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0006868 52.0
HKD3_k127_8659761_2 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 417.0
HKD3_k127_8659761_3 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 320.0
HKD3_k127_8659761_4 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006098 269.0
HKD3_k127_8659761_5 PFAM response regulator receiver K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001694 263.0
HKD3_k127_8659761_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001262 270.0
HKD3_k127_8659761_7 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000002517 220.0
HKD3_k127_8659761_8 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000003691 207.0
HKD3_k127_8659761_9 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000005319 183.0
HKD3_k127_8661241_0 Immune inhibitor A peptidase M6 K09607 - - 1.086e-289 901.0
HKD3_k127_8661241_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 1.334e-204 652.0
HKD3_k127_8661241_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 414.0
HKD3_k127_8661241_3 Acyltransferase K00655 - 2.3.1.51 0.0000000000004124 78.0
HKD3_k127_8661241_4 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000003039 74.0
HKD3_k127_8710033_0 response regulator K07668,K07775 - - 0.000000000000000000000000000000000000000000000000000000000000000107 237.0
HKD3_k127_8710033_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000013 193.0
HKD3_k127_8725105_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 445.0
HKD3_k127_8725105_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000005577 72.0
HKD3_k127_8753113_0 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 582.0
HKD3_k127_8753113_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003015 310.0
HKD3_k127_8753113_2 Putative sensor - - - 0.0000000000000000000000000000000000000000000000000000003716 218.0
HKD3_k127_8753113_3 - - - - 0.0000000000000000000000000000047 123.0
HKD3_k127_8753113_5 - - - - 0.00000000000000005934 85.0
HKD3_k127_8772637_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 316.0
HKD3_k127_8772637_1 Cys/Met metabolism PLP-dependent enzyme K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 297.0
HKD3_k127_8788656_0 Major facilitator Superfamily - - - 3.704e-227 715.0
HKD3_k127_8788656_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000003663 217.0
HKD3_k127_8795388_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 499.0
HKD3_k127_8799058_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 377.0
HKD3_k127_8799058_1 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000001482 182.0
HKD3_k127_8799058_2 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000001141 132.0
HKD3_k127_8807149_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 409.0
HKD3_k127_8807149_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 358.0
HKD3_k127_8807149_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004623 290.0
HKD3_k127_8807149_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000008402 190.0
HKD3_k127_8807149_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000002247 107.0
HKD3_k127_8807149_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000004999 108.0
HKD3_k127_8807149_6 GTP binding - - - 0.0000000000003201 75.0
HKD3_k127_8807149_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K14091 - 1.6.5.3 0.000000000001438 80.0
HKD3_k127_8850695_0 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000003816 119.0
HKD3_k127_8850695_1 Binds the 23S rRNA K02909 - - 0.0000000000000000000000165 103.0
HKD3_k127_8850695_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000001534 107.0
HKD3_k127_8850695_3 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000001092 87.0
HKD3_k127_8861278_0 Ribulose-phosphate 3 epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000003713 253.0
HKD3_k127_8861278_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000006021 158.0
HKD3_k127_8861278_2 PASTA K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.000000000000006234 85.0
HKD3_k127_8866986_0 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000002205 161.0
HKD3_k127_8866986_1 Cysteine-rich secretory protein family - - - 0.000000000000000001902 98.0
HKD3_k127_8886403_0 Subtilase family - - - 0.00000000000000006748 94.0
HKD3_k127_8886784_0 - - - - 0.000000000000000000000000000000000000000000001106 188.0
HKD3_k127_8886784_1 Activator of hsp90 atpase 1 family protein - - - 0.000000000000000000000000000000000000001374 152.0
HKD3_k127_8886784_2 - - - - 0.0000000000000000000000001318 115.0
HKD3_k127_8920943_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 422.0
HKD3_k127_8920943_1 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 377.0
HKD3_k127_8920943_2 positive regulation of transcription, DNA-templated - - - 0.00000000001301 68.0
HKD3_k127_893635_0 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000003462 146.0
HKD3_k127_893635_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000001147 101.0
HKD3_k127_893635_2 BioY protein K03523 - - 0.00000000000000005561 83.0
HKD3_k127_8961559_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 586.0
HKD3_k127_8961559_1 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 454.0
HKD3_k127_8983482_0 Nucleotidyl transferase K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007307 461.0
HKD3_k127_8983482_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 401.0
HKD3_k127_8983482_2 aminopeptidase N - - - 0.00000000000000000000000000000000000000000002517 186.0
HKD3_k127_9002628_0 Tricorn protease homolog K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 615.0
HKD3_k127_9004928_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.579e-243 762.0
HKD3_k127_9004928_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.151e-221 712.0
HKD3_k127_9004928_10 PFAM DinB family protein - - - 0.0000000000000000000002722 103.0
HKD3_k127_9004928_11 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000002737 108.0
HKD3_k127_9004928_12 PFAM Phospholipid glycerol acyltransferase - - - 0.00000000000000000002747 98.0
HKD3_k127_9004928_13 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.0000000000000000003115 98.0
HKD3_k127_9004928_14 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate - - - 0.000000000000000009088 94.0
HKD3_k127_9004928_15 Biotin lipoyl attachment domain-containing protein - - - 0.0000000001828 74.0
HKD3_k127_9004928_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 527.0
HKD3_k127_9004928_3 PFAM isocitrate isopropylmalate dehydrogenase K00030,K07246 - 1.1.1.41,1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 499.0
HKD3_k127_9004928_4 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 424.0
HKD3_k127_9004928_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 389.0
HKD3_k127_9004928_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 338.0
HKD3_k127_9004928_7 Cellulose biosynthesis protein BcsQ K03496 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000002457 237.0
HKD3_k127_9004928_8 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000001216 166.0
HKD3_k127_9004928_9 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000000000000000004534 135.0
HKD3_k127_9076313_0 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 GO:0000287,GO:0003674,GO:0003824,GO:0004016,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006171,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009187,GO:0009190,GO:0009259,GO:0009260,GO:0009975,GO:0009987,GO:0016020,GO:0016829,GO:0016849,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0023052,GO:0030145,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046058,GO:0046390,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052652,GO:0055086,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003321 263.0
HKD3_k127_9112113_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 296.0
HKD3_k127_9112113_1 - K06862 - - 0.000000000000000000000000000000000000000000000000000000002411 207.0
HKD3_k127_9112113_2 ArsC family - - - 0.00000000000000000009906 93.0
HKD3_k127_9112113_3 Belongs to the HpcH HpaI aldolase family K01630,K02510 - 4.1.2.20,4.1.2.52 0.0000568 48.0
HKD3_k127_9112113_4 Pyridoxamine 5'-phosphate oxidase - - - 0.0002298 53.0
HKD3_k127_9141393_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 328.0
HKD3_k127_9141393_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000008257 158.0
HKD3_k127_9141393_2 glycosyl transferase, family 39 - - - 0.00000000000000000001258 108.0
HKD3_k127_9141393_3 Glycosyltransferase family 87 - - - 0.00000000000001378 84.0
HKD3_k127_9152179_0 Periplasmic binding protein domain K10546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 375.0
HKD3_k127_9155221_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1038.0
HKD3_k127_9155221_1 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 473.0
HKD3_k127_9172051_0 glycyl-radical enzyme activating activity K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 554.0
HKD3_k127_9172051_1 PFAM aminotransferase, class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 397.0
HKD3_k127_9172051_2 Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000002083 198.0
HKD3_k127_9172051_3 ECF sigma factor K03088 - - 0.00000000000000000000000963 108.0
HKD3_k127_9172051_4 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0001006 46.0
HKD3_k127_9194377_0 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 444.0
HKD3_k127_9194377_1 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 256.0
HKD3_k127_9194377_2 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000002992 206.0
HKD3_k127_9194377_3 TOBE domain K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000302 183.0
HKD3_k127_9214295_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 334.0
HKD3_k127_9264670_0 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 396.0
HKD3_k127_9264670_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 390.0
HKD3_k127_9264670_2 light absorption - - - 0.00000000000000000000000364 108.0
HKD3_k127_9264670_3 - - - - 0.0001145 48.0
HKD3_k127_9357159_0 PFAM ABC transporter related K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 396.0
HKD3_k127_9357159_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000117 139.0
HKD3_k127_9357159_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000005443 135.0
HKD3_k127_9405446_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 297.0
HKD3_k127_9405446_1 Non-essential cell division protein that could be required for efficient cell constriction - - - 0.0000001953 63.0
HKD3_k127_9485615_0 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 446.0
HKD3_k127_9485615_1 hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 396.0
HKD3_k127_9485615_2 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 401.0
HKD3_k127_9485615_3 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 338.0
HKD3_k127_9485615_4 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000005982 169.0
HKD3_k127_9485615_5 Sulfurtransferase TusA - - - 0.0000000000000000000007009 98.0
HKD3_k127_9485615_6 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000008513 103.0
HKD3_k127_9485615_7 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000009855 91.0
HKD3_k127_9485615_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000003859 79.0
HKD3_k127_9557419_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000007108 143.0
HKD3_k127_95828_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 319.0
HKD3_k127_95828_1 Adenosine/AMP deaminase K01488 - 3.5.4.4 0.000000000000000000000000000000000000000000000000000000000003393 225.0
HKD3_k127_95828_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000008209 220.0
HKD3_k127_95828_3 Haloacid dehalogenase-like hydrolase K01101 - 3.1.3.41 0.000000000000000000000000000000000000000005562 174.0
HKD3_k127_95828_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0003058 49.0
HKD3_k127_974635_0 COG COG0531 Amino acid transporters Amino acid transport and metabolism - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 465.0
HKD3_k127_974635_1 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000004548 248.0
HKD3_k127_974635_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0001562 45.0