logo

Overview

ID MAG01873
Name HKD3_bin.7
Sample SMP0048
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanocellia
Order Methanocellales
Family Methanocellaceae
Genus Methanocella
Species
Assembly information
Completeness (%) 65.27
Contamination (%) 1.07
GC content (%) 58.0
N50 (bp) 1,949
Genome size (bp) 1,751,936

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2427

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1000032_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1163.0
HKD3_k127_1005079_0 Flavoprotein K18853 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0042558,GO:0042559,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901283,GO:1901285,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001115,GO:2001116,GO:2001117,GO:2001118 1.5.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 401.0
HKD3_k127_1005079_1 Fe-S-cluster oxidoreductase K06940 - - 0.000000000000000000000000008898 110.0
HKD3_k127_1034489_0 40-residue YVTN family beta-propeller - - - 2.733e-201 631.0
HKD3_k127_1052847_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 496.0
HKD3_k127_1052847_1 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000005622 151.0
HKD3_k127_1053377_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000001046 256.0
HKD3_k127_1053377_1 Histidine kinase - - - 0.00000000000000005111 92.0
HKD3_k127_1067726_0 Belongs to the NifD NifK NifE NifN family K02587 - - 1.603e-199 624.0
HKD3_k127_1091789_0 Threonyl-tRNA synthetase K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 300.0
HKD3_k127_1091789_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000002624 221.0
HKD3_k127_1091789_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 0.000000000000000000000000000000000000001374 148.0
HKD3_k127_1128614_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 550.0
HKD3_k127_1138508_0 type II secretion system protein K07333 - - 0.0 1111.0
HKD3_k127_1138508_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000001478 167.0
HKD3_k127_1164125_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.447e-213 666.0
HKD3_k127_1164125_1 Trm112p-like protein - - - 0.000000000000000000000000000000001205 131.0
HKD3_k127_1164125_2 - - - - 0.000001289 52.0
HKD3_k127_1170780_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 575.0
HKD3_k127_1170780_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000001052 144.0
HKD3_k127_1174059_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 2.481e-195 614.0
HKD3_k127_1174059_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005491 560.0
HKD3_k127_1181520_0 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000000000000000005059 215.0
HKD3_k127_1181520_1 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000000000000001668 209.0
HKD3_k127_1181520_2 Probable transposase K07496 - - 0.0000000000000000000000001827 106.0
HKD3_k127_1185253_0 PFAM phosphate transporter K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 606.0
HKD3_k127_1185253_1 Belongs to the Protein of K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003464 365.0
HKD3_k127_1200008_0 - - - - 1.825e-262 811.0
HKD3_k127_1200008_1 - - - - 0.00000000000000001157 86.0
HKD3_k127_120437_0 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 561.0
HKD3_k127_120437_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000001574 147.0
HKD3_k127_1209703_0 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 1.259e-307 943.0
HKD3_k127_1209703_1 Chagasin family peptidase inhibitor I42 - - - 0.000000000000000000000000000000000001438 141.0
HKD3_k127_1219425_0 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 280.0
HKD3_k127_1219425_1 Prokaryotic homologs of the JAB domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002752 256.0
HKD3_k127_1219425_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000002323 187.0
HKD3_k127_1219425_3 response regulator, receiver K02658,K03413,K07662,K07667 - - 0.0000000000000000000000000000000000161 135.0
HKD3_k127_1222323_0 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 565.0
HKD3_k127_1222323_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 328.0
HKD3_k127_1240921_0 ABC-type Na efflux pump, permease K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 417.0
HKD3_k127_1240921_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 285.0
HKD3_k127_1271134_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 534.0
HKD3_k127_1271134_1 NIF3 (NGG1p interacting factor 3) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 462.0
HKD3_k127_1271134_2 zinc finger, SWIM - - - 0.000000000000000000000000000000000000000000000000000000000001468 213.0
HKD3_k127_1282265_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 482.0
HKD3_k127_1282265_1 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000004481 182.0
HKD3_k127_1287070_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1223.0
HKD3_k127_1287070_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 9.85e-297 913.0
HKD3_k127_1287070_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 586.0
HKD3_k127_1287070_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 397.0
HKD3_k127_1287070_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000002128 131.0
HKD3_k127_1292836_0 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 552.0
HKD3_k127_1292836_1 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000003469 156.0
HKD3_k127_1297190_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 587.0
HKD3_k127_1297190_1 DUF3160 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 526.0
HKD3_k127_1316495_0 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 345.0
HKD3_k127_1316495_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001151 210.0
HKD3_k127_1319661_0 Peptidase inhibitor I9 K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 578.0
HKD3_k127_1319982_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 560.0
HKD3_k127_1319982_1 Catalyzes the reversible phosphorylation of UMP to UDP K00947 - - 0.000000000000000000001693 93.0
HKD3_k127_1323510_0 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 384.0
HKD3_k127_1323510_1 cell adhesion involved in biofilm formation - - - 0.00000000005993 64.0
HKD3_k127_1329891_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 286.0
HKD3_k127_1329891_1 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000166 187.0
HKD3_k127_134210_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645,K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007921 527.0
HKD3_k127_134210_1 Pyridoxamine 5-phosphate K07005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 326.0
HKD3_k127_134210_3 PFAM ABC transporter related K01990 - - 0.000000000000001742 80.0
HKD3_k127_1344373_0 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 459.0
HKD3_k127_1344373_1 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006447 260.0
HKD3_k127_1344373_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000001226 246.0
HKD3_k127_1347533_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009247 370.0
HKD3_k127_1353361_0 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 467.0
HKD3_k127_1353361_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001002 226.0
HKD3_k127_1353361_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000000001651 212.0
HKD3_k127_1353361_3 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.0000000000000000000000000000000000000000000000000000000004969 203.0
HKD3_k127_1359067_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 2.552e-239 741.0
HKD3_k127_1359067_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 597.0
HKD3_k127_1359067_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 308.0
HKD3_k127_1381613_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 559.0
HKD3_k127_1381613_1 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000001169 225.0
HKD3_k127_1381798_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 7.761e-247 766.0
HKD3_k127_1381798_1 PFAM Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000223 144.0
HKD3_k127_1384465_0 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0 1391.0
HKD3_k127_1384465_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000007527 196.0
HKD3_k127_1396179_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 584.0
HKD3_k127_1396179_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000563 528.0
HKD3_k127_1396179_2 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 459.0
HKD3_k127_1396179_3 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 451.0
HKD3_k127_1396179_4 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000001242 157.0
HKD3_k127_143404_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 445.0
HKD3_k127_143404_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 374.0
HKD3_k127_143404_2 Flavodoxin-like fold - - - 0.0000000000000000000000003565 104.0
HKD3_k127_1438705_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.734e-253 784.0
HKD3_k127_1438705_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 512.0
HKD3_k127_1438705_3 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 374.0
HKD3_k127_1439704_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000001124 231.0
HKD3_k127_1439704_1 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000005845 149.0
HKD3_k127_1440495_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 554.0
HKD3_k127_1440495_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 229.0
HKD3_k127_1440495_2 TIGRFAM cell division ATPase MinD K03609 - - 0.00000000000000000000000000000000000000000000000000000000004538 205.0
HKD3_k127_1455782_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 396.0
HKD3_k127_1455782_1 Tetratricopeptide repeat - - - 0.0000000000000000000003934 99.0
HKD3_k127_1463716_0 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 463.0
HKD3_k127_1463716_1 Flavoprotein K18853 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0034641,GO:0042558,GO:0042559,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0090407,GO:1901283,GO:1901285,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:2001115,GO:2001116,GO:2001117,GO:2001118 1.5.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 389.0
HKD3_k127_1463716_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 295.0
HKD3_k127_1468381_0 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 501.0
HKD3_k127_14700_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0 1451.0
HKD3_k127_14700_1 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 436.0
HKD3_k127_147047_0 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 1.059e-283 875.0
HKD3_k127_1504313_0 - - - - 1.947e-208 653.0
HKD3_k127_1504313_1 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 400.0
HKD3_k127_1504313_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005141 239.0
HKD3_k127_1523839_0 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 491.0
HKD3_k127_1531392_0 PFAM Radical SAM domain protein K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 425.0
HKD3_k127_1531392_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 306.0
HKD3_k127_1531392_2 Protein of unknown function (DUF2551) - - - 0.00000000000000000000000000000000000000000000000000002225 189.0
HKD3_k127_1539821_0 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 361.0
HKD3_k127_1539821_1 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002853 261.0
HKD3_k127_1539821_2 - - - - 0.0000000000000000000000000000000000001274 142.0
HKD3_k127_1546216_0 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009921 255.0
HKD3_k127_1546216_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000000000000000000000218 162.0
HKD3_k127_1555724_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 496.0
HKD3_k127_1555724_1 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000105 77.0
HKD3_k127_1556477_0 Periplasmic copper-binding protein (NosD) - - - 0.0 1116.0
HKD3_k127_1569029_0 PFAM NADH ubiquinone oxidoreductase, 20 K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 316.0
HKD3_k127_1569029_1 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004654 256.0
HKD3_k127_1569029_2 NADH dehydrogenase (Ubiquinone), 30 kDa subunit K00332,K14089 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000005199 219.0
HKD3_k127_1569029_3 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14090 - - 0.00000000000000000000009223 97.0
HKD3_k127_1580104_0 Glycosyl transferase 4-like - - - 1.023e-251 778.0
HKD3_k127_1580104_1 PFAM GCN5-related N-acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 592.0
HKD3_k127_1580104_2 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000584 370.0
HKD3_k127_1580104_3 DNA repair protein K10848 GO:0000003,GO:0000014,GO:0000109,GO:0000110,GO:0000280,GO:0000710,GO:0000712,GO:0000724,GO:0000725,GO:0000726,GO:0000735,GO:0000736,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006259,GO:0006277,GO:0006281,GO:0006289,GO:0006296,GO:0006298,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007059,GO:0007127,GO:0007131,GO:0007530,GO:0007531,GO:0007533,GO:0007534,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0022402,GO:0022413,GO:0022414,GO:0030154,GO:0032502,GO:0032505,GO:0032991,GO:0033554,GO:0033683,GO:0034641,GO:0034645,GO:0034654,GO:0035822,GO:0035825,GO:0036297,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045002,GO:0045132,GO:0045165,GO:0046483,GO:0048285,GO:0048869,GO:0050896,GO:0051304,GO:0051307,GO:0051321,GO:0051716,GO:0061982,GO:0071704,GO:0071840,GO:0071897,GO:0090304,GO:0090305,GO:0097159,GO:0098813,GO:0140013,GO:0140097,GO:1901255,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903046,GO:1990391,GO:1990599 - 0.00000007464 63.0
HKD3_k127_159541_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 426.0
HKD3_k127_159541_1 MafB19-like deaminase K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000001744 239.0
HKD3_k127_159541_2 - - - - 0.000000000000000000000000001088 112.0
HKD3_k127_1599018_0 TIGRFAM TraB family protein - - - 1.992e-235 733.0
HKD3_k127_1599018_1 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 446.0
HKD3_k127_159976_0 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 375.0
HKD3_k127_159976_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001388 236.0
HKD3_k127_159976_2 Protein of unknown function with HXXEE motif - - - 0.0000000000000000000000008001 111.0
HKD3_k127_159976_3 Histidinol phosphatase and related hydrolases of the PHP family K04477 - - 0.0000000000001116 70.0
HKD3_k127_1601964_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 308.0
HKD3_k127_1601964_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000001158 98.0
HKD3_k127_1601964_2 PFAM YcfA-like protein - - - 0.0000000002685 64.0
HKD3_k127_1603294_0 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 466.0
HKD3_k127_1610092_0 haloacid dehalogenase-like hydrolase K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000505 597.0
HKD3_k127_1611856_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 3.581e-263 812.0
HKD3_k127_1611856_1 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 418.0
HKD3_k127_1611856_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000002857 111.0
HKD3_k127_1659593_0 Pfam:DUF91 - - - 5.513e-197 616.0
HKD3_k127_1661619_0 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002152 311.0
HKD3_k127_1661619_1 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 305.0
HKD3_k127_1661619_2 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000004412 261.0
HKD3_k127_167362_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 432.0
HKD3_k127_1674214_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 493.0
HKD3_k127_1685123_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 557.0
HKD3_k127_1693556_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 477.0
HKD3_k127_1693556_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 358.0
HKD3_k127_1700212_0 Winged helix-turn-helix DNA-binding - - - 2.087e-272 840.0
HKD3_k127_1700212_1 - K16915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 467.0
HKD3_k127_1700212_2 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 373.0
HKD3_k127_1700212_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000006908 201.0
HKD3_k127_1707741_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 488.0
HKD3_k127_1707741_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006584 382.0
HKD3_k127_1741624_0 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 438.0
HKD3_k127_1741624_1 - - - - 0.0000000000000000000000000000000000000000000000000000000003764 202.0
HKD3_k127_1741624_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000005489 107.0
HKD3_k127_1741651_0 Molybdopterin oxidoreductase K00201 - 1.2.7.12 1.957e-281 866.0
HKD3_k127_1741651_1 Molydopterin dinucleotide binding domain K00203 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001035 253.0
HKD3_k127_1741651_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000001447 89.0
HKD3_k127_1751784_0 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 472.0
HKD3_k127_1767746_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 573.0
HKD3_k127_1767746_1 Belongs to the peptidase S16 family K06870 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 318.0
HKD3_k127_1767746_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000001663 114.0
HKD3_k127_1768562_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.00000000000000000000000000000000001477 140.0
HKD3_k127_1768562_1 - - - - 0.0000000000132 73.0
HKD3_k127_1787537_0 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 481.0
HKD3_k127_1787537_1 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K15510,K21835 - 1.1.98.2,1.1.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 393.0
HKD3_k127_1787537_2 Protein of unknown function (DUF473) K09135 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008407 241.0
HKD3_k127_1787537_3 PFAM AIG2 family protein - - - 0.0000000000000000000000000000000000000000000000000003841 188.0
HKD3_k127_1787890_0 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009638 364.0
HKD3_k127_1788944_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 373.0
HKD3_k127_1788944_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 282.0
HKD3_k127_1807489_0 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007911 519.0
HKD3_k127_1807489_1 Polynucleotide kinase that can phosphorylate the 5'- hydroxyl groups of both single-stranded RNA (ssRNA) and single- stranded DNA (ssDNA). Exhibits a strong preference for ssRNA K06947 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019205,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0051731,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000009203 231.0
HKD3_k127_1825567_0 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 374.0
HKD3_k127_1825567_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 347.0
HKD3_k127_1825567_2 Histone-like transcription factor (CBF/NF-Y) and archaeal histone - - - 0.0000000000000000000000000000000000716 134.0
HKD3_k127_1831542_0 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 6.525e-200 625.0
HKD3_k127_1831542_1 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000001247 218.0
HKD3_k127_1831542_2 - - - - 0.00000000000000000000000000915 113.0
HKD3_k127_1834594_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 378.0
HKD3_k127_1834594_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 344.0
HKD3_k127_1834594_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 337.0
HKD3_k127_183478_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 391.0
HKD3_k127_183478_1 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 297.0
HKD3_k127_183478_2 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004061 271.0
HKD3_k127_1840640_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 1.556e-242 751.0
HKD3_k127_1840640_1 Major facilitator superfamily - - - 1.249e-207 648.0
HKD3_k127_1840640_2 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 444.0
HKD3_k127_1852310_0 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006357 250.0
HKD3_k127_1852310_1 Phosphate uptake regulator, PhoU - - - 0.00000000000000000000000006383 107.0
HKD3_k127_1879232_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 419.0
HKD3_k127_1879232_1 Uncharacterized protein conserved in archaea (DUF2193) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 387.0
HKD3_k127_1880432_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000008072 200.0
HKD3_k127_1880432_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000004133 145.0
HKD3_k127_1889094_0 Translation initiation factor 2 alpha subunit K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006511 516.0
HKD3_k127_1889094_1 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004224 490.0
HKD3_k127_1889094_2 binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000000000000000000002549 181.0
HKD3_k127_1889094_3 PFAM Ribosomal protein S27E K02978 - - 0.000000000000000000000000000004271 119.0
HKD3_k127_1889094_4 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000000000000000001996 111.0
HKD3_k127_1895238_0 PFAM NADH Ubiquinone plastoquinone (complex I) K14086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 407.0
HKD3_k127_1895238_1 Catalyzes the dephosphorylation of 2-phosphoglycolate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 293.0
HKD3_k127_189670_0 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 597.0
HKD3_k127_189670_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 355.0
HKD3_k127_1921512_0 Pas domain - - - 2.028e-229 713.0
HKD3_k127_1921512_1 Membrane protein of 12 TMs K01992,K07087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 486.0
HKD3_k127_1921512_2 membrane-bound metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 343.0
HKD3_k127_1922702_0 Subtilase family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 366.0
HKD3_k127_1922702_1 Subtilase family K17734 - - 0.000000007994 61.0
HKD3_k127_1934666_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 487.0
HKD3_k127_1934666_1 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 477.0
HKD3_k127_1934666_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 293.0
HKD3_k127_1934666_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000001135 218.0
HKD3_k127_1934666_4 protein conserved in archaea K09732 - - 0.00000000000000000000000000000000000000000000000000004982 187.0
HKD3_k127_1940595_0 PFAM cobalamin synthesis protein P47K - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 417.0
HKD3_k127_1940595_1 PFAM ABC transporter related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 304.0
HKD3_k127_1940595_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000001809 79.0
HKD3_k127_1943774_0 to orf2, orf11, orf12, orf13, orf14, orf15 of fosmid clone 4B7mr3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 392.0
HKD3_k127_1943774_1 to orf2, orf11, orf12, orf13, orf14, orf15 of fosmid clone 4B7mr3 - - - 0.00000000000000000000000000000000000000000000000000006619 193.0
HKD3_k127_1943774_2 Zn-dependent protease with chaperone function K03799 - - 0.00000000000000000000000000000000000000008903 158.0
HKD3_k127_1950991_0 Belongs to the UPF0288 family - - - 3.358e-244 755.0
HKD3_k127_1950991_1 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 456.0
HKD3_k127_1950991_2 Uncharacterized protein conserved in archaea (DUF2112) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 286.0
HKD3_k127_1950991_3 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 283.0
HKD3_k127_1973724_0 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 550.0
HKD3_k127_1973724_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 377.0
HKD3_k127_1973724_2 TPR repeat-containing protein - - - 0.000000000661 61.0
HKD3_k127_1975533_0 MgtC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 344.0
HKD3_k127_1975533_1 Family of unknown function (DUF5350) - - - 0.000000000000000000000000000000001629 129.0
HKD3_k127_1975533_2 - - - - 0.0000000001149 70.0
HKD3_k127_1987777_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 571.0
HKD3_k127_1987777_1 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007382 511.0
HKD3_k127_1987777_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000104 213.0
HKD3_k127_1999047_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0 1142.0
HKD3_k127_2004446_0 Glycosyl transferase 4-like domain - - - 1.086e-231 719.0
HKD3_k127_2006215_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 323.0
HKD3_k127_2006215_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000005677 238.0
HKD3_k127_2018396_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 542.0
HKD3_k127_2018396_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004436 452.0
HKD3_k127_2018396_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001903 224.0
HKD3_k127_2042144_0 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 487.0
HKD3_k127_2042144_1 AAA domain (dynein-related subfamily) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 331.0
HKD3_k127_2054546_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.926e-202 632.0
HKD3_k127_2054546_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 542.0
HKD3_k127_2055405_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 6.565e-200 626.0
HKD3_k127_2055405_1 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000000000000000000000000000000000000000000000000000000001463 223.0
HKD3_k127_2055405_2 COG3387 Glucoamylase and related glycosyl hydrolases - - - 0.000000000000000000000000000002697 119.0
HKD3_k127_2061412_0 V4R K07013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 400.0
HKD3_k127_2061412_1 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 372.0
HKD3_k127_2061412_2 Luciferase-like monooxygenase - - - 0.0000000000000000000004012 96.0
HKD3_k127_2065262_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 5.398e-225 699.0
HKD3_k127_2065262_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000001604 129.0
HKD3_k127_2066125_0 PFAM PEGA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 522.0
HKD3_k127_2085579_0 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002848 276.0
HKD3_k127_2085579_1 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007847 266.0
HKD3_k127_2085579_2 - - - - 0.0000000000000000000000000000001265 128.0
HKD3_k127_2090050_0 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 530.0
HKD3_k127_2090050_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 486.0
HKD3_k127_2090050_2 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0000000000000000005146 86.0
HKD3_k127_2093776_0 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000002392 154.0
HKD3_k127_2103800_0 PFAM Telomeric repeat-binding factor 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 344.0
HKD3_k127_2121169_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 332.0
HKD3_k127_2121169_1 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000003655 164.0
HKD3_k127_2121169_2 Belongs to the UPF0248 family K09715 - - 0.000000000007283 64.0
HKD3_k127_2130561_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 473.0
HKD3_k127_2130561_1 - - - - 0.000000000000000000001167 95.0
HKD3_k127_213746_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.219e-297 919.0
HKD3_k127_2138836_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 1.388e-245 762.0
HKD3_k127_2138836_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000007201 248.0
HKD3_k127_2138836_2 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000000002579 91.0
HKD3_k127_2146790_0 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 498.0
HKD3_k127_2146790_1 DnaB-like helicase C terminal domain K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 475.0
HKD3_k127_2146790_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 409.0
HKD3_k127_2146790_3 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 353.0
HKD3_k127_2146790_4 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 330.0
HKD3_k127_2146790_5 - - - - 0.0000000000000000000000000003383 114.0
HKD3_k127_2146790_6 - - - - 0.0000000000000000000000003258 108.0
HKD3_k127_215947_0 COG0436 Aspartate tyrosine aromatic aminotransferase K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 574.0
HKD3_k127_2169383_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000008417 183.0
HKD3_k127_2169383_1 PhoQ Sensor - - - 0.000000000000000000000000000000000002156 141.0
HKD3_k127_2179620_0 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 546.0
HKD3_k127_2179620_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000008592 201.0
HKD3_k127_2191354_0 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001223 272.0
HKD3_k127_2191354_1 - - - - 0.00000000000000000000000000000000000000000000000008777 179.0
HKD3_k127_2191354_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000005085 72.0
HKD3_k127_2202451_0 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 380.0
HKD3_k127_2202451_1 - - - - 0.00000000000000000000000000000000000000000000000000005715 189.0
HKD3_k127_2203914_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 6.243e-208 648.0
HKD3_k127_2203914_1 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 303.0
HKD3_k127_2203914_2 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000000000000001328 112.0
HKD3_k127_2207954_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 384.0
HKD3_k127_2207954_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000001741 200.0
HKD3_k127_2242294_0 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 356.0
HKD3_k127_2242294_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000002643 233.0
HKD3_k127_2246188_0 Required for chromosome condensation and partitioning K03529 - - 9.082e-236 732.0
HKD3_k127_2246188_1 Segregation and condensation protein ScpA K05896 - - 0.00001401 47.0
HKD3_k127_2264830_0 PFAM band 7 protein - - - 3.645e-215 671.0
HKD3_k127_2264830_1 NfeD-like C-terminal, partner-binding - - - 0.000000000000000000000000000000000000000000000000000000000000008079 216.0
HKD3_k127_2264830_2 - - - - 0.0000000000000000000000000000000000000000006597 158.0
HKD3_k127_2273503_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 320.0
HKD3_k127_2273503_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001156 240.0
HKD3_k127_2287318_0 6-phosphogluconate dehydrogenase-like protein K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 593.0
HKD3_k127_2287318_1 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003865 409.0
HKD3_k127_2287318_2 - - - - 0.0000000000000000000000000000000000000000000000004146 178.0
HKD3_k127_2287318_3 - - - - 0.000000000000000000000000000000000000000000005515 165.0
HKD3_k127_2287318_4 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000002821 146.0
HKD3_k127_2318576_0 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 394.0
HKD3_k127_2330539_0 Major facilitator superfamily - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 509.0
HKD3_k127_2330539_2 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000001759 177.0
HKD3_k127_2364009_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 2.468e-248 771.0
HKD3_k127_2364009_1 Uncharacterized protein conserved in archaea (DUF2209) - - - 0.00000000002165 66.0
HKD3_k127_2364009_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000002632 52.0
HKD3_k127_2377300_0 Integral membrane protein DUF106 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 361.0
HKD3_k127_2377300_1 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000001834 237.0
HKD3_k127_2377300_2 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000141 206.0
HKD3_k127_2377300_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000007717 63.0
HKD3_k127_2382242_0 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 548.0
HKD3_k127_2382242_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 527.0
HKD3_k127_2382242_2 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001882 229.0
HKD3_k127_2382242_3 structural constituent of ribosome K02962 - - 0.00000000000000000000000000007789 115.0
HKD3_k127_2387328_0 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009571 335.0
HKD3_k127_2387328_1 COG3075 Anaerobic glycerol-3-phosphate dehydrogenase K00112 - 1.1.5.3 0.00000000000000000000000000000000000001763 144.0
HKD3_k127_2387328_2 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.0000000000000000000000000000003057 122.0
HKD3_k127_2395891_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 3.976e-205 639.0
HKD3_k127_2395891_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 351.0
HKD3_k127_2395891_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000001931 256.0
HKD3_k127_2401555_0 TIGRFAM drug resistance transporter, Bcr CflA subfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 460.0
HKD3_k127_2401555_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 324.0
HKD3_k127_2401555_2 - - - - 0.00000000000000000000000000000000000000000000000000000007599 198.0
HKD3_k127_2411668_0 PFAM PilT protein domain protein K06865 - - 0.0 1096.0
HKD3_k127_2411668_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 557.0
HKD3_k127_2411668_2 Domain of unknown function (DUF378) K09779 - - 0.000000000000000000000000000000000000001185 147.0
HKD3_k127_2413585_0 Plays a role in the regulation of phosphate uptake K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 363.0
HKD3_k127_2413585_1 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007273 250.0
HKD3_k127_2416256_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 554.0
HKD3_k127_2416256_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 509.0
HKD3_k127_2416256_2 Protein of unknown function (DUF541) K09807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 455.0
HKD3_k127_2416256_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 332.0
HKD3_k127_242277_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 1.927e-198 619.0
HKD3_k127_242277_1 Dimerisation domain of Zinc Transporter - - - 9.544e-195 609.0
HKD3_k127_2439131_0 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 406.0
HKD3_k127_2439131_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003552 255.0
HKD3_k127_2439131_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000004846 59.0
HKD3_k127_2458939_0 DEAD DEAH box helicase domain protein K10896 - - 3.961e-240 744.0
HKD3_k127_2458939_1 PFAM phosphatidate cytidylyltransferase - - - 0.000000000000000000003518 93.0
HKD3_k127_2462294_0 ABC transporter transmembrane region K06147,K11085 - - 1.727e-310 955.0
HKD3_k127_2462294_1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 427.0
HKD3_k127_2472119_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 443.0
HKD3_k127_2472119_1 - - - - 0.000000000000000000000000006349 109.0
HKD3_k127_2475717_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 306.0
HKD3_k127_2489826_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007653 318.0
HKD3_k127_2489826_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004569 267.0
HKD3_k127_2508739_0 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 331.0
HKD3_k127_2508739_1 extracellular matrix structural constituent - - - 0.00000000000000000000000000000000000000000000001119 174.0
HKD3_k127_2522738_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 518.0
HKD3_k127_2522738_1 - - - - 0.0000000000000000002298 88.0
HKD3_k127_2532946_0 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 373.0
HKD3_k127_2532946_1 - - - - 0.0000000000000001028 79.0
HKD3_k127_2538143_0 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 409.0
HKD3_k127_2546783_0 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000001774 216.0
HKD3_k127_2546783_1 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000007929 92.0
HKD3_k127_2580423_0 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000004901 184.0
HKD3_k127_2580423_1 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000009017 156.0
HKD3_k127_2580423_2 Heavy-metal-associated domain K01533,K07213,K07496,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000007831 143.0
HKD3_k127_2610967_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 428.0
HKD3_k127_2610967_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000002181 217.0
HKD3_k127_2610967_2 - - - - 0.000000000000000000003896 93.0
HKD3_k127_2619557_0 - - - - 6.021e-231 717.0
HKD3_k127_2619557_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 588.0
HKD3_k127_2619557_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 287.0
HKD3_k127_2619557_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002956 279.0
HKD3_k127_2619557_4 - - - - 0.00000000000000000000000001395 109.0
HKD3_k127_2619557_5 PFAM type II secretion system protein E - - - 0.00000000007109 64.0
HKD3_k127_2619803_0 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 458.0
HKD3_k127_2619803_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382,K00383 - 1.8.1.4,1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000002163 227.0
HKD3_k127_2632931_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 305.0
HKD3_k127_2632931_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001346 263.0
HKD3_k127_2632931_2 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.00000000000000000000000000000000000000000000000000000009624 195.0
HKD3_k127_2633142_0 COG3387 Glucoamylase and related glycosyl hydrolases - - - 0.0 1073.0
HKD3_k127_2643956_0 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 555.0
HKD3_k127_2643956_1 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K00123,K00390,K00441,K03388,K14121,K22174 - 1.1.98.4,1.12.98.1,1.17.1.9,1.8.4.10,1.8.4.8,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 369.0
HKD3_k127_2643956_2 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008362 246.0
HKD3_k127_2643956_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.00000000000000000000000000000000000001782 151.0
HKD3_k127_2652412_0 PFAM Fumarate lyase K01744 - 4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 381.0
HKD3_k127_2652412_1 - - - - 0.0000000000000000000000007173 104.0
HKD3_k127_2654805_0 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 520.0
HKD3_k127_2654805_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000045 252.0
HKD3_k127_2654805_2 Arsenical pump membrane protein K03893 - - 0.0000000000001466 70.0
HKD3_k127_2661689_0 E1-E2 ATPase K01534 - 3.6.3.3,3.6.3.5 1e-323 994.0
HKD3_k127_266227_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 361.0
HKD3_k127_266227_1 Molybdenum cofactor synthesis K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 325.0
HKD3_k127_2665651_0 COG0857 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 548.0
HKD3_k127_2667152_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 4.2e-201 629.0
HKD3_k127_2667152_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002035 250.0
HKD3_k127_266759_0 Proton-conducting membrane transporter K05565,K12137 - - 2.239e-287 885.0
HKD3_k127_266759_1 Hydrogenase maturation protease K08315 - 3.4.23.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000003948 264.0
HKD3_k127_266759_2 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000001943 79.0
HKD3_k127_2676405_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 1.01e-293 902.0
HKD3_k127_2676405_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002376 489.0
HKD3_k127_2680497_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 471.0
HKD3_k127_2680497_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000002758 173.0
HKD3_k127_2680497_2 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000000000003013 109.0
HKD3_k127_2691849_0 Ammonium Transporter K03320 - - 1.715e-243 754.0
HKD3_k127_2691849_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 497.0
HKD3_k127_2691849_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000000002566 216.0
HKD3_k127_2693399_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 5.824e-312 958.0
HKD3_k127_2693399_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007785 347.0
HKD3_k127_2693399_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 337.0
HKD3_k127_2693399_3 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002178 256.0
HKD3_k127_2693399_4 - - - - 0.000000000000000000000000000000000000000000000000000011 188.0
HKD3_k127_2704882_0 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 412.0
HKD3_k127_2704882_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000000006831 138.0
HKD3_k127_2712412_0 Tetratricopeptide repeat - - - 2.244e-203 635.0
HKD3_k127_2712412_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 577.0
HKD3_k127_2712412_2 Proton-conducting membrane transporter K05565,K12137 - - 0.00000000009461 62.0
HKD3_k127_2727586_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 421.0
HKD3_k127_2727586_1 PFAM Fe-S cluster domain protein K06939 - - 0.00000000000000000002906 93.0
HKD3_k127_2746706_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 2.017e-276 851.0
HKD3_k127_2746885_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 1.208e-232 721.0
HKD3_k127_2746885_1 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 505.0
HKD3_k127_2746885_2 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 359.0
HKD3_k127_2746885_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.0000000000000000000000000000000000000000000009241 166.0
HKD3_k127_2746885_4 NADH ubiquinone oxidoreductase 20 kDa subunit K14128,K17994,K18007 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000001247 127.0
HKD3_k127_2752026_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1352.0
HKD3_k127_2755905_0 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 359.0
HKD3_k127_2755905_1 Transcriptional regulator K09714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009883 241.0
HKD3_k127_2773812_0 adenyl ribonucleotide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 529.0
HKD3_k127_2773812_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 467.0
HKD3_k127_2773812_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 353.0
HKD3_k127_2773812_3 PFAM DsrE family protein K06039,K07235 - - 0.00000000000000000000000000000000000007659 145.0
HKD3_k127_279520_0 Protein of unknown function, DUF255 K06888 - - 2.891e-240 745.0
HKD3_k127_2803438_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 471.0
HKD3_k127_2803438_1 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 430.0
HKD3_k127_2804680_0 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008587 518.0
HKD3_k127_2804680_1 Calcineurin-like phosphoesterase superfamily domain K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000717 412.0
HKD3_k127_2804680_2 Uncharacterized protein, homolog of nitrogen regulatory protein PII - - - 0.0000000000000000000000000000000000000000000000000000000000000008957 221.0
HKD3_k127_2804680_3 Methanogenesis marker protein 6 - - - 0.000000000000000000000000000000000000000000000000000004306 192.0
HKD3_k127_2809712_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.029e-283 873.0
HKD3_k127_2809712_1 binds to the 23S rRNA K02922 - - 0.00000000000000000000000000000000001496 134.0
HKD3_k127_2809757_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 580.0
HKD3_k127_2809757_1 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 308.0
HKD3_k127_2822346_0 Protein of unknown function (DUF460) K09150 - - 0.0 1182.0
HKD3_k127_2822346_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 370.0
HKD3_k127_2822346_2 AIR carboxylase K06898 - - 0.000000000001036 67.0
HKD3_k127_282606_0 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 420.0
HKD3_k127_282606_1 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 291.0
HKD3_k127_2827150_0 arginine catabolic process K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007076 340.0
HKD3_k127_2827150_1 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006536 267.0
HKD3_k127_2827150_2 - - - - 0.000000000000000000000000000000000000000000000000002109 182.0
HKD3_k127_2827150_3 - - - - 0.00000000000000000000000000000000794 127.0
HKD3_k127_2830829_0 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 8.325e-296 909.0
HKD3_k127_2830829_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000002864 240.0
HKD3_k127_2840416_0 Phenazine biosynthesis protein phzf family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000334 191.0
HKD3_k127_2849375_0 integral membrane protein K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008996 593.0
HKD3_k127_2849375_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 408.0
HKD3_k127_2849375_2 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 396.0
HKD3_k127_2849375_3 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000006778 190.0
HKD3_k127_2849375_4 Bifunctional nuclease K08999 - - 0.00000000000000000000000008528 106.0
HKD3_k127_2865235_0 TIGRFAM cell division ATPase MinD K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 503.0
HKD3_k127_2865235_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001259 272.0
HKD3_k127_2865235_2 - - - - 0.00000000000000000000000000000001891 127.0
HKD3_k127_287241_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 566.0
HKD3_k127_287241_1 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 515.0
HKD3_k127_2879312_0 ABC transporter K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 467.0
HKD3_k127_2896570_0 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 506.0
HKD3_k127_2896570_1 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002452 276.0
HKD3_k127_2896570_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009176 255.0
HKD3_k127_2896570_3 - K15342 - - 0.000000000000000000005552 94.0
HKD3_k127_2896961_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 294.0
HKD3_k127_2896961_1 PFAM helix-turn-helix domain protein K07729 - - 0.0000000000000000000000000000001165 124.0
HKD3_k127_2896961_2 - - - - 0.0004119 48.0
HKD3_k127_2899111_0 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 448.0
HKD3_k127_2899111_1 ThiS family K03636 - - 0.0000000000001418 72.0
HKD3_k127_2909168_0 PFAM Thiolase K00626 - 2.3.1.9 3.387e-246 761.0
HKD3_k127_2909168_1 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 1.351e-223 697.0
HKD3_k127_2909168_2 Helix-turn-helix domain protein K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000006417 234.0
HKD3_k127_2921725_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 411.0
HKD3_k127_2921725_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000000002441 218.0
HKD3_k127_2921725_2 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000000000000000000000000000004042 130.0
HKD3_k127_2927071_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 361.0
HKD3_k127_2927071_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000664 150.0
HKD3_k127_2927071_2 - - - - 0.0000000000000000000000000007605 113.0
HKD3_k127_2927071_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K19710 - 2.7.7.53 0.0002152 45.0
HKD3_k127_2931705_0 ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008106 289.0
HKD3_k127_2931705_1 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000001756 227.0
HKD3_k127_2947514_0 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K02588,K21610 - 1.18.6.1,6.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 499.0
HKD3_k127_2947514_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 409.0
HKD3_k127_2947514_2 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.000000000000006369 74.0
HKD3_k127_298887_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003591 362.0
HKD3_k127_2997543_0 CoB--CoM heterodisulfide reductase subunit B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 602.0
HKD3_k127_2997543_1 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 595.0
HKD3_k127_2997543_2 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 506.0
HKD3_k127_2997543_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 322.0
HKD3_k127_2997543_4 - - - - 0.000000000000000000000000000000000000000000000000001614 183.0
HKD3_k127_2997543_5 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000001324 156.0
HKD3_k127_2997543_6 Major facilitator superfamily - - - 0.0000000000003986 68.0
HKD3_k127_301449_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 8.16e-274 844.0
HKD3_k127_301449_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000002547 117.0
HKD3_k127_3041356_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 468.0
HKD3_k127_3041356_1 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000006179 217.0
HKD3_k127_3041356_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000002405 205.0
HKD3_k127_3070683_0 ABC-type cobalt transport system ATPase component K16787 - - 0.00000000000000000000000000000000000000000000000000000000016 215.0
HKD3_k127_3070683_1 PFAM Cobalt transport protein K16785 - - 0.000000000000000000007085 99.0
HKD3_k127_3072105_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 6.306e-200 624.0
HKD3_k127_3072105_1 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 309.0
HKD3_k127_3072105_2 Gar1/Naf1 RNA binding region K07569 - - 0.00000000000000000000000000000000000000000006493 160.0
HKD3_k127_3076515_0 metallopeptidase activity K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 595.0
HKD3_k127_3097984_0 Thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008646 248.0
HKD3_k127_3097984_1 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000001459 228.0
HKD3_k127_3097984_2 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000000000106 190.0
HKD3_k127_3097984_3 - - - - 0.0000000000000000000000000000000000000000000000000002646 187.0
HKD3_k127_3097984_4 - - - - 0.000000000000000000000000000000000000001147 147.0
HKD3_k127_3097984_5 general stress protein B in uncultured methanogenic archaeon (Q0W564) K06884 - - 0.000000000000000000000000000000000000001592 147.0
HKD3_k127_3097984_6 Protein of unknown function (DUF2795) - - - 0.000000000000000000000000000000003233 132.0
HKD3_k127_3101536_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 495.0
HKD3_k127_3101536_1 Uncharacterized protein conserved in archaea (DUF2226) K02039,K09718 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 473.0
HKD3_k127_3101536_2 TIGRFAM cell division ATPase MinD K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 472.0
HKD3_k127_313019_0 thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate K01130 GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 592.0
HKD3_k127_31335_0 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 417.0
HKD3_k127_31335_1 PFAM Rubrerythrin K19824 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004378 244.0
HKD3_k127_31335_2 - - - - 0.000000000000000000000000000000000000000000002633 164.0
HKD3_k127_31335_3 - - - - 0.00000000000000007487 80.0
HKD3_k127_3142625_0 EndoIII-related endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 573.0
HKD3_k127_3142625_1 hydrolase (HAD superfamily) K07025 - - 0.000000000000000000000000000000000000002344 147.0
HKD3_k127_3142625_2 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.0000000000000000000000000000000172 131.0
HKD3_k127_3144447_0 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 3.356e-244 758.0
HKD3_k127_3144447_1 shikimate kinase activity K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 415.0
HKD3_k127_3144447_2 chorismate mutase K04093 - 5.4.99.5 0.0000000000000000000000000000000000000000000001381 170.0
HKD3_k127_3144447_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0003674,GO:0003824,GO:0004764,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0055114,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000136 59.0
HKD3_k127_3168923_0 PFAM SufBD protein K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 455.0
HKD3_k127_3168923_1 ATPases associated with a variety of cellular activities K09013 - - 0.000000000000000000000006439 103.0
HKD3_k127_3182273_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 301.0
HKD3_k127_3182273_1 - - - - 0.00000000000000000000000000003791 117.0
HKD3_k127_3182273_2 Catalyzes the reversible phosphorylation of UMP to UDP K00947 - - 0.00000217 51.0
HKD3_k127_318499_0 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 2.525e-209 651.0
HKD3_k127_3187230_0 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0 1306.0
HKD3_k127_322453_0 Major Facilitator Superfamily - - - 2.06e-213 665.0
HKD3_k127_322453_1 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 229.0
HKD3_k127_322453_2 PFAM PRC-barrel domain - - - 0.0000000000000000000000000000000000000000000000001854 177.0
HKD3_k127_3246098_0 Regulator of chromosome condensation (RCC1) repeat - - - 3.612e-246 764.0
HKD3_k127_3246098_1 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000001919 200.0
HKD3_k127_3282532_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 330.0
HKD3_k127_3282532_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002079 232.0
HKD3_k127_3296479_0 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 377.0
HKD3_k127_3296479_1 AhpC/TSA family K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 291.0
HKD3_k127_3296479_2 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.00000000000000000000000000001697 118.0
HKD3_k127_3302863_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 7.841e-277 852.0
HKD3_k127_3302863_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000001286 50.0
HKD3_k127_3323974_0 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 363.0
HKD3_k127_3326383_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 1.157e-248 769.0
HKD3_k127_3333025_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 436.0
HKD3_k127_3333025_1 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000001765 71.0
HKD3_k127_3340656_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 439.0
HKD3_k127_3340656_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00004269 48.0
HKD3_k127_334432_0 Pfam:DUF2029 - - - 0.0000000000000000000000000000000000000000000000000000001617 204.0
HKD3_k127_334432_1 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000001376 118.0
HKD3_k127_334432_2 GtrA-like protein K00721 - 2.4.1.83 0.00000000000525 70.0
HKD3_k127_3350558_0 membrane protein, required for N-linked glycosylation K07151 - 2.4.99.18 8.275e-226 702.0
HKD3_k127_3350558_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 576.0
HKD3_k127_3350558_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 378.0
HKD3_k127_3350558_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 349.0
HKD3_k127_3356327_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 7.792e-236 731.0
HKD3_k127_3362627_0 - - - - 2.307e-197 621.0
HKD3_k127_3362627_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 323.0
HKD3_k127_3362627_2 - - - - 0.00000000000000000000000000000000004004 138.0
HKD3_k127_3362627_3 - - - - 0.00000000000000000000000237 108.0
HKD3_k127_3362627_4 - - - - 0.00000000000000000000569 92.0
HKD3_k127_338758_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 602.0
HKD3_k127_338758_1 serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 487.0
HKD3_k127_338758_3 KH domain protein K06961 - - 0.0000000000000000000000000000000000115 137.0
HKD3_k127_3389477_0 - - - - 0.0 1044.0
HKD3_k127_3389477_1 to orf3 of fosmid clone 4B7mr3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 420.0
HKD3_k127_3392698_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 2.869e-274 848.0
HKD3_k127_3392698_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002758 239.0
HKD3_k127_3399140_0 DHHA1 domain K07463 - - 1.982e-200 626.0
HKD3_k127_3399140_1 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 418.0
HKD3_k127_3406284_0 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008698 283.0
HKD3_k127_340688_0 Segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 404.0
HKD3_k127_340688_1 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000513 92.0
HKD3_k127_3416573_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 2.745e-245 762.0
HKD3_k127_3416573_1 Belongs to the Protein of K07220 - - 0.000000000000000000004576 94.0
HKD3_k127_343504_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 4.462e-222 689.0
HKD3_k127_343504_1 transcription factor, homolog of eukaryotic MBF1 K00571,K03627,K07332 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000001622 202.0
HKD3_k127_3443729_0 - - - - 0.0 1031.0
HKD3_k127_3443729_1 Iron-sulfur cluster-binding domain - - - 2.694e-219 685.0
HKD3_k127_3447338_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 391.0
HKD3_k127_3447338_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 312.0
HKD3_k127_3447338_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 304.0
HKD3_k127_3452910_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000003844 221.0
HKD3_k127_3452910_1 - - - - 0.0000000000000000000000000000000000000000000000000000000003673 204.0
HKD3_k127_3452910_2 - - - - 0.000000000000000000000000000000000000000000000000000001056 193.0
HKD3_k127_345379_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 379.0
HKD3_k127_345379_1 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000006647 125.0
HKD3_k127_3471809_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0 1103.0
HKD3_k127_3511769_0 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000000000000000000000000000001076 216.0
HKD3_k127_3511769_1 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000000000000000000000000000000000000001107 182.0
HKD3_k127_3511769_2 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000000000000000000001925 126.0
HKD3_k127_3511769_3 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000003964 81.0
HKD3_k127_351415_0 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009633 548.0
HKD3_k127_3519275_0 Rhodanese-like domain K01069 - 3.1.2.6 1.544e-235 731.0
HKD3_k127_3519275_1 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 446.0
HKD3_k127_3519275_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 309.0
HKD3_k127_3538033_0 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000000000000000000305 121.0
HKD3_k127_3538699_0 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 529.0
HKD3_k127_3538699_1 Ferredoxin K05337 - - 0.00000000000000000000000000000000000009911 141.0
HKD3_k127_3538756_0 Bacterial regulatory proteins, tetR family K03577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 376.0
HKD3_k127_3538756_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000006608 144.0
HKD3_k127_3538756_2 ferredoxin iron-sulfur binding - - - 0.0000000000000000000000000000000007808 130.0
HKD3_k127_3544294_0 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 297.0
HKD3_k127_3544294_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 291.0
HKD3_k127_3544294_2 Phosphoribosyl transferase domain K07100 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000134 284.0
HKD3_k127_3544294_3 - - - - 0.00000000000000000000000000000000000000000000000002726 194.0
HKD3_k127_3566877_0 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 463.0
HKD3_k127_3566877_1 PFAM Fe-S cluster domain protein K06939 - - 0.000000000000000000000000000000000000000000000000000000002697 199.0
HKD3_k127_3566877_2 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000001635 121.0
HKD3_k127_3566877_3 Domain of Unknown Function (DUF326) - - - 0.000000000000000000000003579 105.0
HKD3_k127_356746_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 600.0
HKD3_k127_356746_1 - - - - 0.0000000000000000000000000008172 113.0
HKD3_k127_3570759_0 haloacid dehalogenase-like hydrolase K01534 - 3.6.3.3,3.6.3.5 1.488e-210 657.0
HKD3_k127_3570759_1 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.00000000000000000000000000000000000000000000000000000000000000000000329 236.0
HKD3_k127_3570759_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000387 123.0
HKD3_k127_3593764_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 3.409e-279 859.0
HKD3_k127_3593764_1 Helix-hairpin-helix domain K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 551.0
HKD3_k127_3593764_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000000000000000000000001682 240.0
HKD3_k127_3603681_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 8.591e-209 650.0
HKD3_k127_3603681_1 - K03546 - - 0.000000000006265 65.0
HKD3_k127_3616189_0 to Modification methylase in Methanococcus jannaschii (Q58392) and Methanobacterium thermoformicicum (P29568) K00571,K00590 - 2.1.1.113,2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 545.0
HKD3_k127_3616189_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 394.0
HKD3_k127_3616189_2 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000006202 140.0
HKD3_k127_3645071_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.187e-280 862.0
HKD3_k127_3645071_1 Calcineurin-like phosphoesterase superfamily domain K07096 - - 0.0000000000000000000000000000008412 121.0
HKD3_k127_3683198_0 Periplasmic binding protein K02016 - - 2.459e-201 628.0
HKD3_k127_3683198_1 ABC 3 transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 479.0
HKD3_k127_3698056_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 4.904e-314 962.0
HKD3_k127_3698056_1 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.00000000000000000000000000000000000000000000000000000007709 195.0
HKD3_k127_3699861_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003621 462.0
HKD3_k127_3699861_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000009854 195.0
HKD3_k127_3699861_2 COG3634 Alkyl hydroperoxide reductase, large subunit - - - 0.000000000000000000000000000000000000000005514 156.0
HKD3_k127_3703402_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0 1180.0
HKD3_k127_3703693_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 532.0
HKD3_k127_3703693_1 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 477.0
HKD3_k127_3703693_2 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000005447 190.0
HKD3_k127_3733023_0 V4R K07013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 476.0
HKD3_k127_3733023_1 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006269 255.0
HKD3_k127_3735118_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0000000000000000000000000000000000000000000000000000000000000002317 221.0
HKD3_k127_3735118_1 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000000000003489 165.0
HKD3_k127_3735118_2 CAAX protease self-immunity - - - 0.0000000000000000000000000169 120.0
HKD3_k127_3744059_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 606.0
HKD3_k127_3744059_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 492.0
HKD3_k127_375182_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0 1016.0
HKD3_k127_3758571_0 PFAM asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 445.0
HKD3_k127_3758571_1 Polyprenyl synthetase K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009636 392.0
HKD3_k127_3772559_0 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000005748 206.0
HKD3_k127_3772559_1 TIGRFAM Outer membrane protein - - - 0.0001759 53.0
HKD3_k127_3774423_0 COG1522 Transcriptional regulators K03718,K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 323.0
HKD3_k127_3774423_1 COG1522 Transcriptional regulators K03718,K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 292.0
HKD3_k127_3774423_2 helix_turn_helix ASNC type K03718 - - 0.00000000000003487 72.0
HKD3_k127_3774652_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 526.0
HKD3_k127_3774652_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 289.0
HKD3_k127_380639_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 382.0
HKD3_k127_380639_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 283.0
HKD3_k127_380639_2 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000000000000000000000000000001862 138.0
HKD3_k127_382560_0 Flavodoxin domain - - - 0.00000000000000000000000000000000000000006243 156.0
HKD3_k127_382560_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000001098 112.0
HKD3_k127_3829410_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 3.502e-226 701.0
HKD3_k127_384742_0 4-amino-4-deoxy-alpha-L-arabinopyranosyl undecaprenyl phosphate biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002006 272.0
HKD3_k127_384742_1 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000001457 90.0
HKD3_k127_385273_0 heavy metal translocating P-type ATPase - - - 1.551e-218 682.0
HKD3_k127_3858185_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1492.0
HKD3_k127_3858185_1 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 1.665e-225 700.0
HKD3_k127_3858185_2 transcription factor, homolog of eukaryotic MBF1 K00571,K03627,K07332 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000488 256.0
HKD3_k127_3858243_0 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 532.0
HKD3_k127_3858243_1 Phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 304.0
HKD3_k127_3858243_2 PFAM TrkA-N domain protein K10716 - - 0.00000000000000000000000000005184 117.0
HKD3_k127_3859602_0 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.0 1436.0
HKD3_k127_3859602_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 0.0 1106.0
HKD3_k127_3859602_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001388 224.0
HKD3_k127_3859602_3 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000001436 58.0
HKD3_k127_3862146_0 Cysteine-rich domain - - - 3.255e-217 677.0
HKD3_k127_3862146_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K19516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 299.0
HKD3_k127_3862202_0 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 610.0
HKD3_k127_3862202_1 RNA methylase K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000007052 175.0
HKD3_k127_3862202_2 Belongs to the UPF0237 family K07166 - - 0.000000000000000000000000000000000000000000000002158 173.0
HKD3_k127_3892507_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 1.115e-269 834.0
HKD3_k127_3904801_0 PFAM type II secretion system protein E - - - 0.0 1023.0
HKD3_k127_3904801_1 PFAM type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 486.0
HKD3_k127_3904801_2 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 392.0
HKD3_k127_3904801_3 toxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 364.0
HKD3_k127_3916074_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 297.0
HKD3_k127_3926058_0 F420-non-reducing hydrogenase subunit G K14128 - 1.8.98.5 3.868e-204 635.0
HKD3_k127_3926058_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 354.0
HKD3_k127_3926058_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 317.0
HKD3_k127_3926058_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000004214 136.0
HKD3_k127_3926225_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 342.0
HKD3_k127_3926225_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005905 314.0
HKD3_k127_3926225_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001835 262.0
HKD3_k127_3926225_3 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.0000000000000000000000002797 109.0
HKD3_k127_3926225_4 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000007858 91.0
HKD3_k127_3944811_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 413.0
HKD3_k127_3944811_1 Non-histone chromosomal protein MC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001623 242.0
HKD3_k127_3983789_0 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 494.0
HKD3_k127_3983789_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 464.0
HKD3_k127_3983789_2 tetratricopeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004933 255.0
HKD3_k127_3983789_3 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000001017 174.0
HKD3_k127_3985076_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 1.168e-229 711.0
HKD3_k127_3999710_0 heavy metal translocating P-type ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 332.0
HKD3_k127_3999710_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 295.0
HKD3_k127_4000511_0 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 377.0
HKD3_k127_4000511_1 Major facilitator superfamily K03445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002922 269.0
HKD3_k127_4001602_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 296.0
HKD3_k127_4001602_1 COG1131 ABC-type multidrug transport system ATPase component K16907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001165 250.0
HKD3_k127_4047468_0 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000004259 188.0
HKD3_k127_4047468_2 binding domain, Protein - - - 0.0000000000000000000000009624 109.0
HKD3_k127_4048507_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 376.0
HKD3_k127_4048507_1 Glycosyl transferase family group 2 - - - 0.000000001617 61.0
HKD3_k127_4048507_2 GtrA family - - - 0.00005036 45.0
HKD3_k127_4057642_0 PFAM peptidase M50 - - - 3.514e-238 738.0
HKD3_k127_4057642_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000172 277.0
HKD3_k127_4060724_0 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000006231 175.0
HKD3_k127_4060724_1 - - - - 0.0000000000000000000000132 102.0
HKD3_k127_4060724_2 Transcriptional regulator PadR-like family - - - 0.000004433 51.0
HKD3_k127_4060724_3 Transcriptional regulator PadR-like family - - - 0.0003244 48.0
HKD3_k127_4069277_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 2.549e-256 792.0
HKD3_k127_4069277_1 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 379.0
HKD3_k127_4069277_2 Large family of predicted nucleotide-binding domains K07158 - - 0.00000000000000000000000000000000000000000000000000000000000000002307 224.0
HKD3_k127_4110328_0 PQQ enzyme repeat - - - 1.296e-257 798.0
HKD3_k127_4110328_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 324.0
HKD3_k127_4110328_2 Cupin 2 conserved barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 302.0
HKD3_k127_4110328_3 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000114 112.0
HKD3_k127_4111335_0 Protein of unknown function (DUF790) K09744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 346.0
HKD3_k127_4111335_1 helicase superfamily c-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002061 256.0
HKD3_k127_4112523_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 524.0
HKD3_k127_4133509_0 MacB-like periplasmic core domain K02004 - - 6.189e-223 705.0
HKD3_k127_4133509_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 1.511e-202 631.0
HKD3_k127_4133509_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 317.0
HKD3_k127_4164261_0 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 431.0
HKD3_k127_4164261_1 AAA domain (dynein-related subfamily) K03924 - - 0.000000000000000008809 83.0
HKD3_k127_4170786_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 3.569e-288 886.0
HKD3_k127_4170786_1 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000001485 168.0
HKD3_k127_4182278_0 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 336.0
HKD3_k127_4182278_1 H subunit K02107 - - 0.0000000000000000000000000000000001136 135.0
HKD3_k127_4182278_2 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000000000000000006257 131.0
HKD3_k127_4182278_3 - - - - 0.0000000001013 64.0
HKD3_k127_4187897_0 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009018 398.0
HKD3_k127_4187897_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 321.0
HKD3_k127_4187897_2 PFAM HhH-GPD family protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 313.0
HKD3_k127_4187897_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000111 263.0
HKD3_k127_4187897_4 RNase L inhibitor, RLI - - - 0.0000000000000000000000000000000001338 132.0
HKD3_k127_4187897_5 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000006933 77.0
HKD3_k127_419399_0 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 484.0
HKD3_k127_419399_1 UPF0056 membrane protein K05595 - - 0.000000000000000000007624 93.0
HKD3_k127_4209841_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 6.263e-219 680.0
HKD3_k127_4209841_1 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 573.0
HKD3_k127_4209841_2 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 487.0
HKD3_k127_4209841_3 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000000000000000000001538 156.0
HKD3_k127_422127_0 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 559.0
HKD3_k127_422127_1 PFAM GHMP kinase K06982 - 2.7.1.169 0.0000001161 53.0
HKD3_k127_4233937_0 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016725,GO:0052592,GO:0055114 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 557.0
HKD3_k127_4233937_1 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 497.0
HKD3_k127_4233937_2 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008547 425.0
HKD3_k127_4261953_0 Stage II sporulation protein M K06384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 348.0
HKD3_k127_4261953_1 Stage II sporulation protein M K06384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 334.0
HKD3_k127_4261953_2 Membrane protein of unknown function DUF63 - - - 0.0000000000000000000000000000000000004408 141.0
HKD3_k127_4278252_0 DHH family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 567.0
HKD3_k127_4278252_1 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 388.0
HKD3_k127_4278252_2 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001141 258.0
HKD3_k127_4278252_3 NYN domain - - - 0.0000000000358 63.0
HKD3_k127_4297622_0 to orf2, orf11, orf12, orf13, orf14, orf15 of fosmid clone 4B7mr3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 368.0
HKD3_k127_4297622_1 to orf2, orf11, orf12, orf13, orf14, orf15 of fosmid clone 4B7mr3 - - - 0.0000000000000000000000000000000000000000000000001351 180.0
HKD3_k127_4297914_0 von Willebrand factor (vWF) type A domain - - - 1.778e-229 714.0
HKD3_k127_4297914_1 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 509.0
HKD3_k127_430396_0 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 562.0
HKD3_k127_430873_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007161 258.0
HKD3_k127_430873_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000005584 145.0
HKD3_k127_430873_2 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000002563 116.0
HKD3_k127_4311570_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008597 323.0
HKD3_k127_4311570_1 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003668 256.0
HKD3_k127_4311570_2 - - - - 0.0000000000000000000000000000000000000000000000001318 177.0
HKD3_k127_4311570_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000007311 142.0
HKD3_k127_4322602_0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 507.0
HKD3_k127_4322602_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000001381 192.0
HKD3_k127_4336986_0 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.000000000000000000000000000000000000000000000000000000000000000006081 225.0
HKD3_k127_4336986_1 - - - - 0.000000000000000000000000000000000000000000000000000000007129 199.0
HKD3_k127_4336986_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000003206 116.0
HKD3_k127_434171_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 5.251e-227 705.0
HKD3_k127_434171_1 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003624 334.0
HKD3_k127_4343950_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 504.0
HKD3_k127_4343950_1 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 437.0
HKD3_k127_4360762_0 Glycogen debranching enzyme N terminal - - - 8.079e-312 959.0
HKD3_k127_4360762_1 Starch synthase catalytic domain - - - 1.376e-261 806.0
HKD3_k127_4363281_0 TIGRFAM ParB RepB Spo0J family partition protein K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 462.0
HKD3_k127_4363281_1 transferase hexapeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 451.0
HKD3_k127_4363281_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009828 424.0
HKD3_k127_4363281_3 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000017 141.0
HKD3_k127_4363600_0 COG3387 Glucoamylase and related glycosyl hydrolases K01178 - 3.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 507.0
HKD3_k127_4363600_1 Glycosyltransferase family 20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001676 262.0
HKD3_k127_4363976_0 Cytochrome b subunit of formate K14069 - 1.12.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 334.0
HKD3_k127_4363976_1 Nickel-dependent hydrogenase K14068 - 1.12.98.3 0.000000000000000000000000000000000000000000000000000000000000000005567 228.0
HKD3_k127_4364952_0 Peptidase family M50 - - - 3.418e-213 665.0
HKD3_k127_4364952_1 cytidyltransferase-related domain K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000000000000000000001018 233.0
HKD3_k127_4364952_2 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000000000000000001416 195.0
HKD3_k127_4364952_3 cytidyltransferase-related domain K00952 - 2.7.7.1 0.000000000000000000000000000002671 119.0
HKD3_k127_4364952_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000001448 116.0
HKD3_k127_4364952_5 PFAM Glycosyl transferase, group 1 K03525 - 2.7.1.33 0.0003889 50.0
HKD3_k127_4370415_0 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 384.0
HKD3_k127_4370415_1 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 295.0
HKD3_k127_4373931_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.199e-194 621.0
HKD3_k127_4373931_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00009551 44.0
HKD3_k127_4378031_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 363.0
HKD3_k127_4399584_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 5.871e-262 807.0
HKD3_k127_4403787_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0050897,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 3.481e-244 755.0
HKD3_k127_4403787_1 Permease - - - 6.656e-206 644.0
HKD3_k127_4403787_2 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 340.0
HKD3_k127_4403787_3 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.00000000000000000000000001888 109.0
HKD3_k127_440832_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.508e-211 657.0
HKD3_k127_440832_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000006427 201.0
HKD3_k127_440832_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000001783 93.0
HKD3_k127_4409307_0 Glycosyltransferase family 20 - - - 1.495e-212 662.0
HKD3_k127_4438193_0 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 484.0
HKD3_k127_4438193_1 - - - - 0.00000000000000000004066 94.0
HKD3_k127_4442492_0 Uncharacterized ACR, COG1993 K09137 - - 0.0000000000000000000000000000000000000000001433 163.0
HKD3_k127_4442492_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000009527 123.0
HKD3_k127_4464622_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.209e-210 661.0
HKD3_k127_4464622_1 ABC-type cobalt transport system, ATPase component K02006 - - 0.0000000000000000000006317 96.0
HKD3_k127_4469253_0 Type II/IV secretion system protein - - - 0.0 1235.0
HKD3_k127_4469253_1 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 412.0
HKD3_k127_4469253_2 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 375.0
HKD3_k127_4469253_3 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 331.0
HKD3_k127_4480935_0 UvrD REP helicase K03657,K07465 - 3.6.4.12 2.97e-224 697.0
HKD3_k127_4480935_1 DEAD/H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 376.0
HKD3_k127_4483531_0 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 496.0
HKD3_k127_4483531_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 464.0
HKD3_k127_4500066_0 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 569.0
HKD3_k127_4500066_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 432.0
HKD3_k127_4500066_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000003185 187.0
HKD3_k127_4521672_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 4.905e-302 930.0
HKD3_k127_4521672_1 Flavodoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000006313 219.0
HKD3_k127_4529179_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008702 389.0
HKD3_k127_4529179_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000002981 208.0
HKD3_k127_4546539_0 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 473.0
HKD3_k127_4546539_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 385.0
HKD3_k127_4551309_0 Uncharacterized protein conserved in archaea (DUF2114) - - - 7.541e-318 974.0
HKD3_k127_4551309_1 Domain of unknown function (DUF1894) - - - 0.000000000000000000000000000000000000000000000000000000000000000745 220.0
HKD3_k127_4565090_0 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 337.0
HKD3_k127_4565090_2 - - - - 0.00000000000000000000007406 98.0
HKD3_k127_4574006_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 2.998e-271 837.0
HKD3_k127_4580513_1 UV-endonuclease UvdE K13281 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000355 259.0
HKD3_k127_4580513_2 - - - - 0.000000000000000000000006149 102.0
HKD3_k127_4586522_0 ATP-grasp domain K06914 - 6.3.4.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 545.0
HKD3_k127_4586522_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005439 324.0
HKD3_k127_4586522_2 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000009274 240.0
HKD3_k127_4586522_3 - - - - 0.000000000000000000000000000000000000000000000000000000000004932 209.0
HKD3_k127_4605174_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 294.0
HKD3_k127_4608266_0 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 365.0
HKD3_k127_4608266_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008042 257.0
HKD3_k127_4608266_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005365 249.0
HKD3_k127_4608266_3 TIGRFAM MIP family channel K02440,K06188 - - 0.0000000000000000000000000000000000001047 142.0
HKD3_k127_4625532_0 membrane protein, required for N-linked glycosylation K07151 - 2.4.99.18 1.649e-197 618.0
HKD3_k127_4625532_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006417 380.0
HKD3_k127_4625532_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008776 231.0
HKD3_k127_4637244_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis - - - 1.558e-209 659.0
HKD3_k127_4643800_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001464 272.0
HKD3_k127_4643800_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001682 245.0
HKD3_k127_4643800_2 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000000000000000000000000000000000000000004358 182.0
HKD3_k127_4643800_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000005332 112.0
HKD3_k127_4656802_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0 1037.0
HKD3_k127_4659872_0 PFAM Transglutaminase-like - - - 4.274e-196 616.0
HKD3_k127_4659872_1 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000002256 58.0
HKD3_k127_4660079_0 - - - - 3.524e-207 647.0
HKD3_k127_4660079_1 Domain of unknown function DUF128 K21640 - - 0.00000000000000000007758 90.0
HKD3_k127_4663409_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.039e-229 711.0
HKD3_k127_4663409_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 606.0
HKD3_k127_4663409_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000001725 224.0
HKD3_k127_4663409_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000002197 75.0
HKD3_k127_4666108_0 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001759 272.0
HKD3_k127_4666108_1 cheY-homologous receiver domain K07668 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002061 248.0
HKD3_k127_4674427_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 462.0
HKD3_k127_4674427_1 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000994 269.0
HKD3_k127_4674439_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 7.786e-227 707.0
HKD3_k127_4674439_1 Protein of unknown function (DUF4013) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008582 387.0
HKD3_k127_4674439_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000982 372.0
HKD3_k127_4674439_3 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005632 341.0
HKD3_k127_4674439_4 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000001455 213.0
HKD3_k127_4674439_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000398 140.0
HKD3_k127_4680378_0 DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 430.0
HKD3_k127_4680378_1 DNA polymerase Ligase (LigD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 286.0
HKD3_k127_4691944_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.213e-321 985.0
HKD3_k127_4691944_1 PFAM regulatory protein, ArsR K07721 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 372.0
HKD3_k127_4702701_0 ATP-grasp domain K06913 - - 2.062e-197 616.0
HKD3_k127_4702701_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 503.0
HKD3_k127_4702701_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 387.0
HKD3_k127_4702701_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 381.0
HKD3_k127_4702701_4 methyltransferase small K07579 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 380.0
HKD3_k127_4702701_5 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 352.0
HKD3_k127_4702701_6 Non-histone chromosomal protein MC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 306.0
HKD3_k127_4702701_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000000000000000000000000000000000000000001276 179.0
HKD3_k127_4702701_8 - - - - 0.00000000000000000000000001081 109.0
HKD3_k127_4717359_0 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 478.0
HKD3_k127_4717359_1 4Fe-4S dicluster domain - - - 0.0000000000000007643 78.0
HKD3_k127_4717432_0 LOR SDH bifunctional enzyme conserved - - - 9.189e-268 826.0
HKD3_k127_4717432_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000003647 101.0
HKD3_k127_4730987_0 Flavodoxin - - - 6.454e-245 758.0
HKD3_k127_4730987_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 379.0
HKD3_k127_4730987_2 Rubrerythrin - - - 0.000000000001583 68.0
HKD3_k127_4730987_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000001561 64.0
HKD3_k127_475842_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 1.532e-198 622.0
HKD3_k127_475842_1 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 463.0
HKD3_k127_475842_2 TIGRFAM cell division ATPase MinD K03609 - - 0.000000000000000000000000000000000000000000000000000000000000000000001682 240.0
HKD3_k127_4764736_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 428.0
HKD3_k127_4764736_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 362.0
HKD3_k127_4778284_0 Methyltransferase K15429 - 2.1.1.228 1.247e-201 631.0
HKD3_k127_4778284_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 289.0
HKD3_k127_4782005_0 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 302.0
HKD3_k127_4782005_1 TIGRFAM UbiD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001542 237.0
HKD3_k127_4792316_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 512.0
HKD3_k127_4792316_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 355.0
HKD3_k127_4792316_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 345.0
HKD3_k127_4792316_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 297.0
HKD3_k127_4796659_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 339.0
HKD3_k127_4796659_1 COG0607 Rhodanese-related sulfurtransferase K03406,K21028 - 2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000589 217.0
HKD3_k127_4799981_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 471.0
HKD3_k127_4799981_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 359.0
HKD3_k127_480707_0 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 392.0
HKD3_k127_480707_1 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 357.0
HKD3_k127_4821984_0 Pas domain s-box - - - 0.00000000000000000000000000000000000001052 154.0
HKD3_k127_4834484_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 566.0
HKD3_k127_4834484_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002481 254.0
HKD3_k127_4834484_2 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000002373 187.0
HKD3_k127_4834484_3 Pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.00000003625 54.0
HKD3_k127_4839135_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000001516 170.0
HKD3_k127_4839135_1 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000002016 133.0
HKD3_k127_4865775_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 324.0
HKD3_k127_4865775_1 - - - - 0.0000000000000000000000000000000000003061 141.0
HKD3_k127_4873908_0 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 518.0
HKD3_k127_4873908_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000004426 249.0
HKD3_k127_4873908_2 4-hydroxybenzoate synthetase (chorismate lyase) K03181,K06984 - 2.4.2.54,4.1.3.40 0.00000000000000000000000000000000000000001252 153.0
HKD3_k127_4874550_0 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 5.257e-275 848.0
HKD3_k127_4874550_1 Methyl-coenzyme M reductase operon protein D K03422 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 321.0
HKD3_k127_4874550_2 PFAM Methyl-coenzyme M reductase operon protein C K03421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004068 255.0
HKD3_k127_4881198_0 Luciferase-like monooxygenase K21835 - 1.1.98.5 4.237e-196 612.0
HKD3_k127_4897416_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645,K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003013 422.0
HKD3_k127_4897416_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 401.0
HKD3_k127_4918972_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 3.349e-253 782.0
HKD3_k127_4918972_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0000000000000000008281 85.0
HKD3_k127_4928720_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 534.0
HKD3_k127_4928720_1 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 421.0
HKD3_k127_4939737_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 1.729e-264 818.0
HKD3_k127_4939737_1 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000008039 239.0
HKD3_k127_494853_0 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 428.0
HKD3_k127_494853_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 394.0
HKD3_k127_494853_2 PFAM methyltransferase small K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000002571 193.0
HKD3_k127_4952961_0 ABC transporter K00400,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 340.0
HKD3_k127_4952961_1 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008857 314.0
HKD3_k127_4952961_2 COG2041 Sulfite oxidase and related enzymes K16925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007599 274.0
HKD3_k127_4971369_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 469.0
HKD3_k127_4971369_1 N-terminal domain of (some) glycogen debranching enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 411.0
HKD3_k127_4971369_2 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007105 351.0
HKD3_k127_4971759_0 archaeosine synthase activity K07557 - 2.6.1.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 453.0
HKD3_k127_4971759_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 381.0
HKD3_k127_4971759_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000006351 216.0
HKD3_k127_4978111_0 PFAM ABC transporter related K01990 - - 2.881e-203 636.0
HKD3_k127_4978111_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 453.0
HKD3_k127_4978111_2 PFAM transcriptional regulator PadR family protein - - - 0.0000000000000000004633 86.0
HKD3_k127_4986325_0 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 599.0
HKD3_k127_4986325_1 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 390.0
HKD3_k127_4986325_2 - - - - 0.00000000000000000000000000000000000000005731 153.0
HKD3_k127_4986325_3 - - - - 0.000000000000001906 79.0
HKD3_k127_4986325_4 by modhmm - - - 0.00000000003637 63.0
HKD3_k127_4992177_0 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 387.0
HKD3_k127_4992177_1 - - - - 0.00005449 52.0
HKD3_k127_4996051_0 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002043 239.0
HKD3_k127_5000856_0 Mn2 dependent serine threonine protein kinase - - - 3.298e-236 735.0
HKD3_k127_5000856_1 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 493.0
HKD3_k127_5000856_2 Belongs to the carbohydrate kinase PfkB family K00852,K21057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.15,2.7.1.213 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006983 319.0
HKD3_k127_5000856_3 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000318 265.0
HKD3_k127_5000884_0 Subtilase family K17734 - - 2.335e-262 812.0
HKD3_k127_5000884_1 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 545.0
HKD3_k127_5000884_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000003197 229.0
HKD3_k127_5000884_3 - - - - 0.0000000000000000004013 89.0
HKD3_k127_5004071_0 tRNA synthetases class II (A) K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 425.0
HKD3_k127_5004071_1 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 361.0
HKD3_k127_500755_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 507.0
HKD3_k127_500755_1 Domain of unknown function DUF128 K21640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003402 247.0
HKD3_k127_5011663_0 Archaeal Nre, N-terminal - - - 1.598e-259 801.0
HKD3_k127_5011663_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 524.0
HKD3_k127_5011663_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 491.0
HKD3_k127_5011663_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001918 214.0
HKD3_k127_5021105_0 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002631 514.0
HKD3_k127_5031376_0 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 553.0
HKD3_k127_5031376_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 423.0
HKD3_k127_5031376_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 297.0
HKD3_k127_5034773_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K22222 - - 7.418e-233 724.0
HKD3_k127_5034773_1 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 522.0
HKD3_k127_5034773_2 ZPR1-related zinc finger protein K06874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 383.0
HKD3_k127_5034773_3 RuvA, C-terminal domain K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 357.0
HKD3_k127_5034773_4 Crossover junction endodeoxyribonuclease RuvC K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 318.0
HKD3_k127_5034773_5 Pfam:DUF552 K09152 - - 0.000000000000000000000000000000001713 129.0
HKD3_k127_5046683_0 COG1361 S-layer domain - - - 1.655e-257 796.0
HKD3_k127_5046683_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 602.0
HKD3_k127_5060880_0 - - - - 1.9e-228 710.0
HKD3_k127_5060880_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 426.0
HKD3_k127_5060880_2 PFAM TatD-related deoxyribonuclease K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 328.0
HKD3_k127_5060880_3 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 289.0
HKD3_k127_5060880_4 - - - - 0.00000000000000000000000008358 110.0
HKD3_k127_506391_0 PBS lyase HEAT domain protein repeat-containing protein - - - 7.04e-232 721.0
HKD3_k127_506391_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003694 485.0
HKD3_k127_506391_2 - - - - 0.000000000000000000000000000000000000000000000003519 173.0
HKD3_k127_506391_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000001629 97.0
HKD3_k127_5066989_0 Phage tail sheath protein K06907 - - 1.824e-278 857.0
HKD3_k127_5066989_1 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 494.0
HKD3_k127_5066989_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003221 276.0
HKD3_k127_5066989_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000007655 231.0
HKD3_k127_5066989_5 - - - - 0.0000000000000000000000000000000000002343 146.0
HKD3_k127_5067223_0 Nickel-dependent hydrogenase K14068 - 1.12.98.3 3.369e-258 797.0
HKD3_k127_5067223_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K14070 - 1.12.98.3 6.33e-209 651.0
HKD3_k127_5075984_0 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 454.0
HKD3_k127_5075984_2 Winged helix-turn-helix DNA-binding - - - 0.0000000000000000000000004071 105.0
HKD3_k127_5075984_3 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000398 90.0
HKD3_k127_5093866_0 Elongation factor Tu C-terminal domain K03231 - - 5.389e-246 761.0
HKD3_k127_5093866_1 Elongation factor Tu C-terminal domain K03231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009875 248.0
HKD3_k127_5093866_2 metallopeptidase activity - - - 0.0000000000000000002001 89.0
HKD3_k127_5099399_0 ABC-2 family transporter protein K01992 - - 5.592e-212 662.0
HKD3_k127_5099399_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000003514 131.0
HKD3_k127_5107444_0 SMART Elongator protein 3 MiaB NifB K06936 - - 1.616e-215 670.0
HKD3_k127_5107444_1 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006114 320.0
HKD3_k127_5112391_0 SMART Elongator protein 3 MiaB NifB - - - 0.0 1040.0
HKD3_k127_5112391_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 390.0
HKD3_k127_5112391_2 Fe-S-cluster oxidoreductase K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 340.0
HKD3_k127_5112391_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 334.0
HKD3_k127_5112391_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 283.0
HKD3_k127_5112391_5 Cupredoxin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001138 241.0
HKD3_k127_5112391_6 Cupredoxin-like domain - - - 0.00000000000000000000000000000000000000000000000001214 181.0
HKD3_k127_5112391_7 - - - - 0.00000000000000000000000000004954 117.0
HKD3_k127_5112391_8 Redoxin K03564 - 1.11.1.15 0.0000000009854 66.0
HKD3_k127_5117260_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 533.0
HKD3_k127_5117260_1 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 297.0
HKD3_k127_5127775_0 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 462.0
HKD3_k127_5127775_1 Hemerythrin HHE cation binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 397.0
HKD3_k127_5127775_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 312.0
HKD3_k127_5127775_3 PQ loop repeat K15383 - - 0.00000000000000000000000152 106.0
HKD3_k127_5132734_0 Sodium hydrogen exchanger K03455 - - 0.0 1056.0
HKD3_k127_5132734_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 465.0
HKD3_k127_5132734_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 394.0
HKD3_k127_5134760_0 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 405.0
HKD3_k127_5134760_1 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004018 242.0
HKD3_k127_5138998_0 Glycosyl hydrolase family 57 K07405 - 3.2.1.1 4.067e-285 878.0
HKD3_k127_5138998_1 MFS_1 like family - - - 3.115e-237 736.0
HKD3_k127_5140605_0 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 300.0
HKD3_k127_5140605_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000003191 233.0
HKD3_k127_5152296_0 - - - - 4.07e-255 790.0
HKD3_k127_5161668_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 411.0
HKD3_k127_5161668_1 - - - - 0.000000000000000003641 83.0
HKD3_k127_5164424_0 - - - - 0.0000000000000000000000000000009139 128.0
HKD3_k127_5164424_1 - - - - 0.00006424 50.0
HKD3_k127_5169427_0 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 408.0
HKD3_k127_5169427_1 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000000000000000000000000000002 135.0
HKD3_k127_5169427_2 - - - - 0.00000000000000000000000000000000006036 134.0
HKD3_k127_5170537_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 8.287e-264 813.0
HKD3_k127_5170537_1 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002317 256.0
HKD3_k127_5170537_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001364 252.0
HKD3_k127_5170537_3 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.0000000000000000000000000000000000000000000000000000000000000000001195 232.0
HKD3_k127_5170537_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.0000000000000000000000000000000000000000168 153.0
HKD3_k127_5170537_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000000000000000000000009662 131.0
HKD3_k127_5177143_0 DEAD DEAH box helicase domain protein K03725 - - 2.444e-230 714.0
HKD3_k127_5177143_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001661 263.0
HKD3_k127_5177143_2 - - - - 0.000000000000000000000000000000000000000000000000000698 185.0
HKD3_k127_5177143_3 - - - - 0.00000000000000000000000000000000000000000000007072 171.0
HKD3_k127_5183628_0 Has ATPase and non-specific DNA-binding activities K07456 - - 0.0 1324.0
HKD3_k127_5183628_1 ABC transporter transmembrane region K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000009094 189.0
HKD3_k127_5188193_0 PAS domain K02488 - 2.7.7.65 0.000000000000000000000002026 117.0
HKD3_k127_5204805_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.607e-215 669.0
HKD3_k127_5204805_1 Bacterio-opsin activator HTH K06930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 405.0
HKD3_k127_5204805_2 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 366.0
HKD3_k127_5204805_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 309.0
HKD3_k127_5208972_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 1.346e-303 934.0
HKD3_k127_5208972_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 8.361e-298 916.0
HKD3_k127_5208972_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 1.123e-255 790.0
HKD3_k127_5210665_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 9.886e-197 616.0
HKD3_k127_5210665_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 502.0
HKD3_k127_5210665_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 366.0
HKD3_k127_5210665_3 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000001573 159.0
HKD3_k127_5228217_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 580.0
HKD3_k127_5228217_1 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000001152 206.0
HKD3_k127_5228217_2 SPTR Transposase, IS4 family protein - - - 0.0000000000000000108 86.0
HKD3_k127_5228528_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 593.0
HKD3_k127_5228528_1 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 522.0
HKD3_k127_5231432_0 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 358.0
HKD3_k127_5231432_1 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001901 273.0
HKD3_k127_5231432_2 - - - - 0.000000000000000000000000000006914 118.0
HKD3_k127_5232281_0 Phenazine biosynthesis protein phzf family K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 542.0
HKD3_k127_5232281_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000108 163.0
HKD3_k127_5234673_0 - - - - 1.396e-208 651.0
HKD3_k127_5244596_0 Oligopeptide transporter OPT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 419.0
HKD3_k127_5244596_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 367.0
HKD3_k127_5244596_2 - - - - 0.000000000000000000000000000000000000000001023 157.0
HKD3_k127_5253789_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.503e-301 925.0
HKD3_k127_5253789_1 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000005669 184.0
HKD3_k127_5253789_2 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000004887 81.0
HKD3_k127_5262978_0 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 386.0
HKD3_k127_5262978_1 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000001808 94.0
HKD3_k127_5262978_2 ABC-type multidrug transport system, permease component K01992 - - 0.00000002225 55.0
HKD3_k127_527310_0 PFAM Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 432.0
HKD3_k127_527310_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 371.0
HKD3_k127_527310_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002261 251.0
HKD3_k127_527310_4 COG3385 FOG Transposase and inactivated derivatives - - - 0.000000000000000000007458 102.0
HKD3_k127_527310_5 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.0000000002408 67.0
HKD3_k127_527811_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 512.0
HKD3_k127_5278898_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 3.073e-245 758.0
HKD3_k127_5278898_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 368.0
HKD3_k127_5278898_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000002043 177.0
HKD3_k127_5278898_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000001229 88.0
HKD3_k127_5280746_0 COG0607 Rhodanese-related sulfurtransferase K03406,K21028 - 2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000798 269.0
HKD3_k127_5280746_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) K03406 - - 0.000000000000000000000000000000000000000000000004295 186.0
HKD3_k127_5280801_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 329.0
HKD3_k127_5280801_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 304.0
HKD3_k127_5280801_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 304.0
HKD3_k127_5280801_3 YCII-related domain - - - 0.00000000000000000000003144 102.0
HKD3_k127_5282416_0 PFAM phosphoesterase, RecJ domain protein - - - 1.381e-267 826.0
HKD3_k127_5282416_1 ribosomal protein S15 K02956 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 301.0
HKD3_k127_5282416_2 S-adenosylmethionine decarboxylase K01611 - 4.1.1.50 0.00000000000000000000000003843 107.0
HKD3_k127_5282416_3 - - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 - 0.000000000007308 68.0
HKD3_k127_5293752_0 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 472.0
HKD3_k127_5293752_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000008743 160.0
HKD3_k127_5294824_0 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 331.0
HKD3_k127_5294824_1 Molybdate transporter of MFS superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007964 249.0
HKD3_k127_5294896_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000005421 164.0
HKD3_k127_5294896_1 Protein of unknown function (DUF998) - - - 0.0000000000000000001074 91.0
HKD3_k127_5294896_2 Domain of unknown function (DUF4405) - - - 0.00000001008 62.0
HKD3_k127_5295975_0 PspA/IM30 family K03969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 404.0
HKD3_k127_5295975_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000002115 220.0
HKD3_k127_5295975_2 - - - - 0.0000000000000000000000000000000000000000000000001706 178.0
HKD3_k127_5296912_0 Cysteine-rich small domain K08260 - 3.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 581.0
HKD3_k127_5296912_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 319.0
HKD3_k127_5296912_2 MMPL family K06994 - - 0.000000000000000000000000000000000000000000000000000000000000000000006661 236.0
HKD3_k127_5296912_3 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.00000000000000000000000000000000000000000000000000000000000000000427 229.0
HKD3_k127_5303117_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002381 252.0
HKD3_k127_5303117_1 Protein of unknown function (DUF1616) - - - 0.0000000000000000000000000000000000000000000000000000002467 196.0
HKD3_k127_5317610_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 1.45e-198 632.0
HKD3_k127_5317610_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 294.0
HKD3_k127_5317610_2 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.000000000000000000000000000000007439 127.0
HKD3_k127_5319705_0 Metallophosphoesterase K06953 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 412.0
HKD3_k127_5319705_1 Thioredoxin K03671 - - 0.000000000000000000000000000000002163 130.0
HKD3_k127_5333773_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit K01546 - 3.6.3.12 0.0 1012.0
HKD3_k127_5333773_1 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007488 500.0
HKD3_k127_5333773_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.00000000000000000000000000000000000000000000000003459 179.0
HKD3_k127_5336471_0 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 393.0
HKD3_k127_5336471_1 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 304.0
HKD3_k127_5346597_0 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003974 594.0
HKD3_k127_5366321_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 380.0
HKD3_k127_5366321_1 threonine efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 336.0
HKD3_k127_5369364_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 3.227e-264 817.0
HKD3_k127_5369364_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 510.0
HKD3_k127_5369364_2 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 396.0
HKD3_k127_5369364_3 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K03399,K03795,K06042,K22011 GO:0003674,GO:0003824,GO:0005488,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016829,GO:0016852,GO:0017144,GO:0018130,GO:0019251,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0050897,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.289,4.99.1.11,4.99.1.3,5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000000001885 207.0
HKD3_k127_5369364_4 - - - - 0.0000000000000000000000000000000000001618 141.0
HKD3_k127_5369364_5 - - - - 0.0000000000000004081 78.0
HKD3_k127_5379588_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 525.0
HKD3_k127_5406944_0 TPR repeat - - - 0.000000000000000000000000000000000002339 141.0
HKD3_k127_5406944_1 ATPases associated with a variety of cellular activities K02017 - 3.6.3.29 0.00000000000000000000000000000000858 129.0
HKD3_k127_5406944_2 Cobalt transport protein K16785 - - 0.000000000000000000005705 95.0
HKD3_k127_5407065_0 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 481.0
HKD3_k127_5407065_2 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000002587 87.0
HKD3_k127_5411909_0 CBS domain containing protein K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 477.0
HKD3_k127_5443072_0 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 279.0
HKD3_k127_5443072_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000001149 204.0
HKD3_k127_5443253_0 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000003665 220.0
HKD3_k127_5443253_1 protein conserved in bacteria K09956 - - 0.00008729 50.0
HKD3_k127_5445587_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 477.0
HKD3_k127_5445587_1 Domain of unknown function (DUF366) K09139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 355.0
HKD3_k127_5445587_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000344 239.0
HKD3_k127_5445587_3 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000002073 229.0
HKD3_k127_5448291_0 Tripartite tricarboxylate transporter TctA family K08971 - - 1.7e-233 726.0
HKD3_k127_5448291_1 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 433.0
HKD3_k127_5448291_2 PBS lyase K22221 - - 0.0000000000000000001012 99.0
HKD3_k127_5450784_0 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 513.0
HKD3_k127_5450784_1 PFAM GTP-binding protein HSR1-related K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 422.0
HKD3_k127_5450784_2 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 380.0
HKD3_k127_5450784_3 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.0000000000000000000000000000000000000000000000000000000000000001329 222.0
HKD3_k127_5450784_4 Zn-ribbon containing protein K07163 - - 0.0000000000000000000000000000000000005015 141.0
HKD3_k127_5470285_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 7.174e-208 648.0
HKD3_k127_5482872_0 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 361.0
HKD3_k127_5482872_1 Rieske-like [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000001773 190.0
HKD3_k127_5482872_2 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000001327 175.0
HKD3_k127_5482872_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003637 134.0
HKD3_k127_5482872_4 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000004403 81.0
HKD3_k127_5487849_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 3.964e-303 930.0
HKD3_k127_5491246_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 3.569e-206 648.0
HKD3_k127_5518314_0 Nudix hydrolase K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000008288 244.0
HKD3_k127_5518781_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126 - 1.8.98.5 2.148e-294 905.0
HKD3_k127_5518781_1 F420-non-reducing hydrogenase subunit G K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 410.0
HKD3_k127_5518781_2 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000002226 216.0
HKD3_k127_5518781_3 Roadblock LC7 family protein K07131 - - 0.0000000000001996 74.0
HKD3_k127_5532639_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 2.186e-279 860.0
HKD3_k127_5532639_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
HKD3_k127_5532639_2 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a modified Entner-Doudoroff pathway K00068,K18124,K18125 GO:0000166,GO:0003674,GO:0003824,GO:0004344,GO:0005488,GO:0005515,GO:0005534,GO:0005536,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006012,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009987,GO:0016043,GO:0016052,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019320,GO:0019388,GO:0019595,GO:0022607,GO:0030246,GO:0033498,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043933,GO:0044085,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0046430,GO:0046872,GO:0046914,GO:0046983,GO:0047910,GO:0047936,GO:0048029,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051262,GO:0051287,GO:0055114,GO:0065003,GO:0070401,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.1.1.140,1.1.1.359,1.1.1.360 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 286.0
HKD3_k127_5538685_0 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 484.0
HKD3_k127_5538685_1 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 301.0
HKD3_k127_5538685_2 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00578 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000004429 205.0
HKD3_k127_5538685_3 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00582 - 2.1.1.86 0.00000000000000000000000000000001221 127.0
HKD3_k127_5538685_4 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00583 - 2.1.1.86 0.0000000000000000000000000000007674 123.0
HKD3_k127_5538685_5 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00579 - 2.1.1.86 0.000000000000000000000007244 100.0
HKD3_k127_5539201_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 3.508e-220 684.0
HKD3_k127_5539201_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 262.0
HKD3_k127_5539201_2 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000000000001656 233.0
HKD3_k127_5539201_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002614 237.0
HKD3_k127_5565370_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000005003 71.0
HKD3_k127_5565656_0 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 500.0
HKD3_k127_5565656_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 288.0
HKD3_k127_5581385_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 614.0
HKD3_k127_5581385_1 general stress protein B in uncultured methanogenic archaeon (Q0W564) K06884 - - 0.000000000000000000000000000000009148 130.0
HKD3_k127_5581385_2 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000004066 101.0
HKD3_k127_5582435_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 577.0
HKD3_k127_5586354_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009436 329.0
HKD3_k127_5586354_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 298.0
HKD3_k127_5594551_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 320.0
HKD3_k127_5594551_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009479 317.0
HKD3_k127_5594551_2 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000001082 246.0
HKD3_k127_5594551_3 - - - - 0.00000000000000000000000000000000000000000000000000000000006671 205.0
HKD3_k127_5603304_0 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 2.92e-200 625.0
HKD3_k127_5603304_1 PFAM cyclase family protein K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 408.0
HKD3_k127_5603304_2 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 372.0
HKD3_k127_5611645_0 oligoendopeptidase F - - - 2.109e-204 637.0
HKD3_k127_561201_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 3.986e-203 634.0
HKD3_k127_561201_1 Rieske 2Fe-2S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001711 239.0
HKD3_k127_561201_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000001683 161.0
HKD3_k127_5624675_0 B-block binding subunit of TFIIIC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 355.0
HKD3_k127_5624675_1 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 308.0
HKD3_k127_5624675_2 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000000000000000000001073 147.0
HKD3_k127_5624675_3 Flavodoxin - - - 0.0000000000000000000000000000000000002375 140.0
HKD3_k127_5626184_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 417.0
HKD3_k127_5626184_1 PFAM ribosomal protein S8E K02995 - - 0.000000000000000008082 82.0
HKD3_k127_5660017_0 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000004547 216.0
HKD3_k127_5660017_1 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000001453 169.0
HKD3_k127_5661669_0 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 7.694e-234 724.0
HKD3_k127_5661669_1 PFAM glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 479.0
HKD3_k127_5662774_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000000000000000000000000000000001068 196.0
HKD3_k127_5662774_1 metal-dependent membrane protease K07052 - - 0.00000000000000000000000000000000000000000000000005768 178.0
HKD3_k127_5673293_0 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 5.77e-229 713.0
HKD3_k127_567752_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 1.309e-199 627.0
HKD3_k127_567752_1 zinc metalloprotease whose natural substrate is K06974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 440.0
HKD3_k127_5688419_0 SPFH domain-Band 7 family - - - 1.845e-233 726.0
HKD3_k127_5688419_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
HKD3_k127_5689384_0 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 324.0
HKD3_k127_5689384_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 301.0
HKD3_k127_5693680_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 338.0
HKD3_k127_5693680_1 TIGRFAM UbiD family - - - 0.000000000000000000001169 94.0
HKD3_k127_5693680_2 - - - - 0.0000000000005237 68.0
HKD3_k127_569556_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000008776 231.0
HKD3_k127_569556_1 domain protein - - - 0.00000000000000000000000000000003223 131.0
HKD3_k127_5696914_0 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 2.336e-238 741.0
HKD3_k127_5696914_1 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 439.0
HKD3_k127_5696914_2 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.0000000000000000000000000000000000001645 141.0
HKD3_k127_5701873_0 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.000000000000000000000000000000000000000000000000000000008055 201.0
HKD3_k127_571198_0 Elongator protein 3 MiaB NifB - - - 7.692e-199 622.0
HKD3_k127_571198_1 - - - - 0.0000000004657 60.0
HKD3_k127_5714864_0 ABC transporter K09691 - - 8.249e-276 850.0
HKD3_k127_5714864_1 PFAM ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 402.0
HKD3_k127_5717328_0 PFAM elongation factor Tu domain 2 - - - 1.828e-207 646.0
HKD3_k127_5717328_1 Roadblock LC7 family protein K06945,K07131 - - 0.00000000000000000000000000000000000000000007749 160.0
HKD3_k127_5717328_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000008896 126.0
HKD3_k127_5727198_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 360.0
HKD3_k127_5727198_1 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000001773 145.0
HKD3_k127_5727198_2 Biotin-lipoyl like K02005 - - 0.0000000000001451 72.0
HKD3_k127_5735780_0 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 454.0
HKD3_k127_5735780_1 PFAM metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 408.0
HKD3_k127_5735780_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002543 235.0
HKD3_k127_5735780_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000001491 120.0
HKD3_k127_5737468_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 430.0
HKD3_k127_5737468_1 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000006515 229.0
HKD3_k127_575070_0 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 415.0
HKD3_k127_575070_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 355.0
HKD3_k127_575070_2 helix_turn_helix ASNC type K03718,K03719 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 296.0
HKD3_k127_575070_3 metal-dependent membrane protease K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000156 282.0
HKD3_k127_575070_4 - - - - 0.000000000000000000000000000000000000000000000000001501 183.0
HKD3_k127_575070_5 PFAM dihydropteroate synthase, DHPS - - - 0.0000000000000000000000000000000000000003687 149.0
HKD3_k127_5751840_0 Exonuclease V - a 5' deoxyribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 549.0
HKD3_k127_5751840_1 - - - - 0.0000000000000000000000000000000000000000000007985 166.0
HKD3_k127_5751840_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.000000000000000006903 83.0
HKD3_k127_5763460_0 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002176 273.0
HKD3_k127_5763460_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000003363 50.0
HKD3_k127_5766720_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 1.231e-202 636.0
HKD3_k127_5766720_1 Membrane protein of unknown function DUF63 - - - 0.0000000000000000000000000000000000000000000000000000000000000003198 228.0
HKD3_k127_5766720_2 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000002229 114.0
HKD3_k127_5768888_0 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 518.0
HKD3_k127_5768888_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 423.0
HKD3_k127_5768888_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000004997 175.0
HKD3_k127_5768888_3 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000001483 91.0
HKD3_k127_5784263_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 467.0
HKD3_k127_5784263_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000002971 76.0
HKD3_k127_5787028_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 479.0
HKD3_k127_5787028_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000002323 237.0
HKD3_k127_5787028_2 - - - - 0.000000000000000000000000000000000001504 141.0
HKD3_k127_5787028_3 - - - - 0.000000000000000000000000009098 114.0
HKD3_k127_5787028_4 - - - - 0.00000000000000000000001767 100.0
HKD3_k127_5794612_0 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 548.0
HKD3_k127_5794612_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K00443 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 481.0
HKD3_k127_5794612_2 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000002147 223.0
HKD3_k127_5794612_3 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.00000001528 55.0
HKD3_k127_5797946_0 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 266.0
HKD3_k127_5797946_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001969 267.0
HKD3_k127_5797946_3 TIGRFAM MIP family channel K02440,K06188 - - 0.000000000000000000000000000006629 118.0
HKD3_k127_5803655_0 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 4.602e-276 850.0
HKD3_k127_5803655_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000001229 76.0
HKD3_k127_5812146_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 462.0
HKD3_k127_5812146_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000003235 175.0
HKD3_k127_5812146_2 - - - - 0.00000000000000000000000000000000000000000005376 163.0
HKD3_k127_5812146_3 Transcriptional regulator, AbrB family K06193 - - 0.000000000000000000000001742 102.0
HKD3_k127_5820722_0 Phosphohydrolase K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 523.0
HKD3_k127_5820722_1 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000007031 235.0
HKD3_k127_5828992_1 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.00000000000000000000000000000000000000000000003346 171.0
HKD3_k127_5831332_0 COG2041 Sulfite oxidase and related enzymes K16925 - - 0.00000000000000000000000000002671 133.0
HKD3_k127_5834861_0 protein kinase activity K06915 - - 0.0 1080.0
HKD3_k127_5834861_1 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 421.0
HKD3_k127_5834861_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000001247 187.0
HKD3_k127_5834861_3 - - - - 0.000000000000000000000005438 102.0
HKD3_k127_5836183_0 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 415.0
HKD3_k127_5836183_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000005997 252.0
HKD3_k127_5836183_2 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000001075 215.0
HKD3_k127_5836708_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 417.0
HKD3_k127_5836708_1 COG1520 FOG WD40-like repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 395.0
HKD3_k127_5836708_2 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003028 270.0
HKD3_k127_5858367_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 355.0
HKD3_k127_5858367_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000845 161.0
HKD3_k127_5890722_0 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000000000000000000000000000000000000000000000000000000000002321 212.0
HKD3_k127_5890722_1 COG0003 Oxyanion-translocating ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000006934 169.0
HKD3_k127_5890722_2 DNA binding protein K06930 - - 0.000000000008705 73.0
HKD3_k127_5892074_0 carbon starvation protein CstA K06200 - - 1.055e-240 752.0
HKD3_k127_5892813_0 Protease prsW family - - - 2.102e-290 907.0
HKD3_k127_5892813_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 319.0
HKD3_k127_5892813_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000822 308.0
HKD3_k127_5892813_4 - - - - 0.000000002436 59.0
HKD3_k127_5898882_0 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 394.0
HKD3_k127_5920202_0 Polyprenyl synthetase K02523 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 535.0
HKD3_k127_5920202_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 291.0
HKD3_k127_5921720_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 432.0
HKD3_k127_5921720_1 PFAM amino acid-binding ACT domain protein K06862 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 306.0
HKD3_k127_5929357_0 Domain of unknown function (DUF362) K07138 - - 5.794e-210 654.0
HKD3_k127_5929357_1 PFAM Nucleotidyl transferase - - - 3.61e-208 651.0
HKD3_k127_5929357_2 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 359.0
HKD3_k127_5958348_0 Haloacid dehalogenase-like hydrolase K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008373 308.0
HKD3_k127_5962001_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 2.364e-278 857.0
HKD3_k127_5962001_1 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000004173 199.0
HKD3_k127_596637_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 325.0
HKD3_k127_596637_1 PFAM Transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 301.0
HKD3_k127_5973637_0 Pfam:DUF91 - - - 0.0 1125.0
HKD3_k127_5973637_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 355.0
HKD3_k127_5973637_2 Pyridoxamine 5-phosphate K07005 - - 0.000000000000000000000000000000005065 128.0
HKD3_k127_5975968_1 Mitochondrial biogenesis AIM24 - - - 0.00000000000009058 70.0
HKD3_k127_5977670_0 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 382.0
HKD3_k127_5977670_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000001252 238.0
HKD3_k127_5977670_2 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.000000000000000000000000000000000000000000000000000000000000000002165 228.0
HKD3_k127_5977670_3 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000003325 195.0
HKD3_k127_5977670_4 ThiS family K03636 - - 0.0000000000000000000000000000000000000000000001141 169.0
HKD3_k127_5977670_5 Uncharacterised conserved protein UCP006557, signal transduction - - - 0.000000000000006255 80.0
HKD3_k127_5977670_6 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000004236 63.0
HKD3_k127_5984467_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 5.104e-223 700.0
HKD3_k127_5984467_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000004286 63.0
HKD3_k127_5986958_0 PFAM Xylose isomerase domain protein TIM barrel K01151,K03335 - 3.1.21.2,4.2.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 502.0
HKD3_k127_5986958_1 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 424.0
HKD3_k127_5986958_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 403.0
HKD3_k127_5989239_0 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 5.556e-204 635.0
HKD3_k127_5994267_0 MMPL family K06994 - - 6.427e-235 734.0
HKD3_k127_6001276_0 ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 318.0
HKD3_k127_6008846_0 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 2.048e-229 714.0
HKD3_k127_6008846_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004501 551.0
HKD3_k127_6008846_2 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 357.0
HKD3_k127_6008846_3 Fumarase C-terminus K01678 - 4.2.1.2 0.00000000000000000000001367 100.0
HKD3_k127_6010938_0 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 358.0
HKD3_k127_6010938_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 346.0
HKD3_k127_6010938_2 PFAM regulatory protein, ArsR K21903 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 287.0
HKD3_k127_6011318_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 470.0
HKD3_k127_6011318_1 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 347.0
HKD3_k127_6011318_2 transcriptional - - - 0.0000000000000000000000000000000000000002011 150.0
HKD3_k127_6016298_0 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000000000001061 202.0
HKD3_k127_6016298_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000004327 168.0
HKD3_k127_6016298_2 glucosylceramidase activity - - - 0.0000000000000000000000000000000000000000006321 159.0
HKD3_k127_6016298_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000005379 153.0
HKD3_k127_6026687_0 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 578.0
HKD3_k127_6026687_1 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 442.0
HKD3_k127_6026687_2 Thiol disulfide interchange protein K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 384.0
HKD3_k127_6026687_3 CBS domain - - - 0.00000000000000000000000001124 109.0
HKD3_k127_6027795_0 MgtE intracellular N domain - - - 8.308e-259 801.0
HKD3_k127_6027795_1 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 400.0
HKD3_k127_6027795_2 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000000000000000000000000000000000000000000002512 235.0
HKD3_k127_6030167_0 DNA polymerase beta domain protein region K09717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 610.0
HKD3_k127_6030167_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 560.0
HKD3_k127_6045657_0 Domain of unknown function (DUF1743) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 527.0
HKD3_k127_6045657_1 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000009519 126.0
HKD3_k127_6061367_0 Cytochrome C biogenesis protein transmembrane region - - - 2.847e-203 635.0
HKD3_k127_6062100_0 CoA binding domain K01905 - 6.2.1.13 3.786e-278 857.0
HKD3_k127_6062100_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 541.0
HKD3_k127_6062100_2 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 424.0
HKD3_k127_6062100_3 HMGL-like K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 415.0
HKD3_k127_6062100_4 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002687 405.0
HKD3_k127_6062100_5 Protein of unknown function (DUF1284) K09706 - - 0.00000000000000000000000000000000000000000000000000000000000000001063 224.0
HKD3_k127_6063456_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.135e-275 846.0
HKD3_k127_6066060_0 in RNase L inhibitor, RLI K06174 - - 9.243e-256 790.0
HKD3_k127_6067391_0 PFAM ABC-type thiamin-related transport system, permease component 1 K16925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002917 246.0
HKD3_k127_6067391_1 ABC transporter K00400,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000004141 213.0
HKD3_k127_6067391_2 COG2041 Sulfite oxidase and related enzymes K16925 - - 0.0000000000000000000000000000000000000000000000000000002704 196.0
HKD3_k127_6068648_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1170.0
HKD3_k127_6072690_0 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 306.0
HKD3_k127_6072690_1 flavodoxin K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000002624 182.0
HKD3_k127_6072690_2 - - - - 0.0000002968 53.0
HKD3_k127_6085395_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 4.446e-258 800.0
HKD3_k127_6085395_1 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.00000000000000002467 84.0
HKD3_k127_6093554_0 antibiotic catabolic process K14166 - - 3.543e-224 696.0
HKD3_k127_6093554_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 7.096e-197 614.0
HKD3_k127_6101531_0 Oxidoreductase family, C-terminal alpha/beta domain K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 414.0
HKD3_k127_6101531_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 319.0
HKD3_k127_6103944_0 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 574.0
HKD3_k127_6103944_1 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 305.0
HKD3_k127_6110737_0 Protein-export membrane protein SecD K03072 - - 1.39e-252 782.0
HKD3_k127_6110737_1 Involved in protein export K03074 - - 0.0000000000000000000000000000000000000000000000000000000004525 215.0
HKD3_k127_6112750_0 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 583.0
HKD3_k127_6112750_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 332.0
HKD3_k127_6112750_2 PFAM sigma-70 region 4 domain protein K09714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005424 241.0
HKD3_k127_6122628_0 Major Facilitator Superfamily - - - 8.162e-206 642.0
HKD3_k127_6133989_0 PFAM AIR synthase related protein K07388 - - 4.869e-282 871.0
HKD3_k127_6133989_1 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 476.0
HKD3_k127_6133989_2 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 411.0
HKD3_k127_6133989_3 Belongs to the UPF0179 family K09730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 291.0
HKD3_k127_6133989_4 response regulator, receiver K02485,K02490,K03413 - - 0.00000000000000000000000000000000000000000000000000000000062 203.0
HKD3_k127_6133989_5 Winged helix-turn-helix - - - 0.0000000000000000000000004387 104.0
HKD3_k127_6149209_0 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004807 459.0
HKD3_k127_6158316_0 Involved in regulation of DNA replication K10725 - - 2.537e-214 666.0
HKD3_k127_6158316_1 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.000000000000000000000000000000000000000000000000000000003276 203.0
HKD3_k127_6158316_2 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.00000000000000000001834 90.0
HKD3_k127_615844_0 Thioredoxin K03671 - - 0.000000000000000000000000002268 114.0
HKD3_k127_615844_1 Pfam:DUF1628 - - - 0.0001112 51.0
HKD3_k127_615844_2 NMT1-like family - - - 0.0002031 44.0
HKD3_k127_6160639_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.0 1143.0
HKD3_k127_6160639_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 289.0
HKD3_k127_6160639_2 Metallo-beta-lactamase superfamily K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005276 256.0
HKD3_k127_6160639_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002357 222.0
HKD3_k127_6169980_0 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 396.0
HKD3_k127_6169980_1 DGC domain - - - 0.00000000000000000000000000000000000000000000002524 173.0
HKD3_k127_6183929_0 - - - - 1.746e-205 641.0
HKD3_k127_6183929_1 - - - - 0.000000000007863 65.0
HKD3_k127_6195206_0 HMGL-like K01649 - 2.3.3.13 6.31e-244 753.0
HKD3_k127_620055_0 PFAM major facilitator superfamily MFS_1 K08223 - - 7.14e-243 754.0
HKD3_k127_620055_1 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 392.0
HKD3_k127_620055_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000004854 138.0
HKD3_k127_6208852_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.044e-196 612.0
HKD3_k127_6208852_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 606.0
HKD3_k127_6208852_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000000000000000000000000000000000000002632 200.0
HKD3_k127_6208852_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000000000000000000000000000002121 179.0
HKD3_k127_6211979_0 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 346.0
HKD3_k127_6211979_1 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 304.0
HKD3_k127_6211979_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000002938 138.0
HKD3_k127_6218278_0 phosphoesterase RecJ domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 544.0
HKD3_k127_6218278_1 protein conserved in archaea - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 511.0
HKD3_k127_6218278_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 392.0
HKD3_k127_6218278_3 Metallo-beta-lactamase superfamily K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000262 270.0
HKD3_k127_622228_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.067e-214 666.0
HKD3_k127_622228_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 333.0
HKD3_k127_622228_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 282.0
HKD3_k127_622228_3 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001627 274.0
HKD3_k127_6222307_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 1.406e-254 787.0
HKD3_k127_6222307_1 Helix-turn-helix domain protein K03627 - - 0.00000000000000000000000000000000000001811 145.0
HKD3_k127_6239778_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0 1116.0
HKD3_k127_6239778_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 300.0
HKD3_k127_6239778_2 amino acid K03294 - - 0.00000000000000000000000000000001356 128.0
HKD3_k127_6246745_0 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000001419 177.0
HKD3_k127_6246745_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000005885 100.0
HKD3_k127_6265650_0 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 462.0
HKD3_k127_6265650_1 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003541 278.0
HKD3_k127_6265650_2 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000007289 212.0
HKD3_k127_6265650_3 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000003886 197.0
HKD3_k127_6285805_0 DEAD DEAH box helicase domain protein K03725 - - 4.19e-196 614.0
HKD3_k127_6285805_1 - - - - 0.00000000000000000000000000000000000000000001593 162.0
HKD3_k127_6288213_0 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 473.0
HKD3_k127_6288213_1 PFAM BioY protein K03523 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 325.0
HKD3_k127_6288213_2 ATPases associated with a variety of cellular activities K16786 - - 0.000000000000001761 85.0
HKD3_k127_6301287_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 1e-215 671.0
HKD3_k127_6301287_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 421.0
HKD3_k127_6301287_2 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 322.0
HKD3_k127_6305842_0 Permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 403.0
HKD3_k127_6305842_2 - - - - 0.00000000000000000000000000000000000000009362 152.0
HKD3_k127_6312497_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 3.401e-235 729.0
HKD3_k127_6312497_1 PFAM TfuA domain protein, core - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 363.0
HKD3_k127_6312497_2 - - - - 0.000000000000000000000000000000006084 127.0
HKD3_k127_6327296_0 PFAM glutamine amidotransferase, class-II - - - 2.157e-231 717.0
HKD3_k127_6327296_1 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 396.0
HKD3_k127_6327296_2 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 343.0
HKD3_k127_6327296_3 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 293.0
HKD3_k127_6345730_0 - - - - 0.000000000000000000000000000000000000000272 155.0
HKD3_k127_6345730_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000004493 104.0
HKD3_k127_6349887_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 515.0
HKD3_k127_6349887_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 471.0
HKD3_k127_6349887_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 439.0
HKD3_k127_6349887_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 423.0
HKD3_k127_6349887_4 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 323.0
HKD3_k127_6349887_5 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000001639 132.0
HKD3_k127_6349887_6 PBS lyase K22221 - - 0.00000002557 59.0
HKD3_k127_6377074_0 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 592.0
HKD3_k127_6377074_1 Mitochondrial small ribosomal subunit Rsm22 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 457.0
HKD3_k127_6378391_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 382.0
HKD3_k127_6378391_1 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000006208 196.0
HKD3_k127_6411149_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K03829 - - 0.0000000000000000000000000000000000000000000000000000000003278 205.0
HKD3_k127_6411149_1 Domain of unknown function (DUF4405) - - - 0.000000002693 62.0
HKD3_k127_6431799_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 588.0
HKD3_k127_6437572_0 Major facilitator superfamily - - - 1.874e-239 744.0
HKD3_k127_6437572_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007381 262.0
HKD3_k127_6437572_2 Sodium hydrogen exchanger - - - 0.0000000000000000000000000000000000000000000000000000000000000000001312 232.0
HKD3_k127_6437572_3 UPF0391 membrane protein - - - 0.0000000000000000000000000000009064 121.0
HKD3_k127_6441863_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 535.0
HKD3_k127_6451001_0 Bacterial transcription activator, effector binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 291.0
HKD3_k127_6451001_1 Sodium:alanine symporter family K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009668 244.0
HKD3_k127_6451001_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000005066 188.0
HKD3_k127_6451001_3 Sodium:alanine symporter family K03310 - - 0.0000000000000000000000000000008269 122.0
HKD3_k127_6470804_0 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002988 276.0
HKD3_k127_6470804_1 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.00000000000000000000000000000000000000000001337 163.0
HKD3_k127_6481767_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 443.0
HKD3_k127_6481767_1 Winged helix-turn-helix DNA-binding - - - 0.000000000000000001286 86.0
HKD3_k127_6481767_2 PFAM ABC transporter related K01990 - - 0.00000000000001386 74.0
HKD3_k127_6500293_0 Major facilitator superfamily - - - 2.584e-225 702.0
HKD3_k127_6500293_1 PFAM GPR1 FUN34 yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 372.0
HKD3_k127_6500293_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000828 250.0
HKD3_k127_6500293_3 - - - - 0.00000000009308 61.0
HKD3_k127_6501983_0 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 370.0
HKD3_k127_6501983_1 ATPases associated with a variety of cellular activities K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001653 267.0
HKD3_k127_650782_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 1.513e-252 779.0
HKD3_k127_6508142_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 468.0
HKD3_k127_6508142_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000001852 222.0
HKD3_k127_6508142_2 cation diffusion facilitator family transporter - - - 0.00000001081 57.0
HKD3_k127_6508638_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 5.208e-245 759.0
HKD3_k127_6508638_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000002248 94.0
HKD3_k127_6508638_2 - - - - 0.0000003622 52.0
HKD3_k127_6508658_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1089.0
HKD3_k127_6508658_1 Domain of unknown function (DUF4872) - - - 1.31e-201 629.0
HKD3_k127_6515912_0 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007331 567.0
HKD3_k127_6515912_1 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.00000000000000000000000000000000006514 133.0
HKD3_k127_6515912_2 PFAM Dinitrogenase iron-molybdenum cofactor - - - 0.000000005867 56.0
HKD3_k127_6530390_0 Pfam:KaiC K08482 - - 1.496e-268 830.0
HKD3_k127_6551355_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 3.464e-249 771.0
HKD3_k127_6551355_1 PFAM LmbE family protein K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 446.0
HKD3_k127_6551355_2 - - - - 0.00000000000000000000000000000000000000000000000003645 187.0
HKD3_k127_6557553_0 Histidinol phosphatase and related hydrolases of the PHP family K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 346.0
HKD3_k127_6557553_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 317.0
HKD3_k127_655836_0 Catalyzes the reversible phosphorylation of UMP to UDP K00947 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 495.0
HKD3_k127_655836_1 PBP superfamily domain K05772 - - 0.000000000000000000005169 93.0
HKD3_k127_6562607_0 PFAM TPR repeat-containing protein K00575 - 2.1.1.80 6.732e-194 607.0
HKD3_k127_6562607_1 - - - - 0.000000000000000000000000000000000000000148 152.0
HKD3_k127_6565578_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1607.0
HKD3_k127_6565578_1 - - - - 0.00000000000000000000000000000000000000001032 154.0
HKD3_k127_6573450_0 PFAM PKD domain containing protein - - - 1.62e-233 724.0
HKD3_k127_6573450_1 methanogenesis marker protein 11 - - - 6.716e-226 701.0
HKD3_k127_6573566_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 2.747e-277 855.0
HKD3_k127_6573566_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 7.285e-249 776.0
HKD3_k127_6573566_2 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 611.0
HKD3_k127_6588381_0 Conserved region in glutamate synthase - - - 0.0 1042.0
HKD3_k127_6589955_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 412.0
HKD3_k127_6589955_1 TIGRFAM small GTP-binding protein K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 380.0
HKD3_k127_6589955_2 signal peptidase I K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 373.0
HKD3_k127_6589955_3 - - - - 0.0000000000000000000000000000000007788 131.0
HKD3_k127_6594114_0 PFAM Flavodoxin nitric oxide synthase K19817 - 1.5.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 329.0
HKD3_k127_6594114_1 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000000000000000001943 133.0
HKD3_k127_6594231_0 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 411.0
HKD3_k127_6607780_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000001547 231.0
HKD3_k127_6607780_1 MgtC family - - - 0.000000000000000000002311 93.0
HKD3_k127_6608517_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 595.0
HKD3_k127_6608517_1 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000006449 173.0
HKD3_k127_6670303_0 zinc finger - - - 3.717e-204 637.0
HKD3_k127_6670426_0 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 344.0
HKD3_k127_6670426_1 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004188 241.0
HKD3_k127_6671561_0 MscS Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005196 438.0
HKD3_k127_6671561_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000004164 92.0
HKD3_k127_6672987_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 8.057e-241 745.0
HKD3_k127_6672987_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 535.0
HKD3_k127_6672987_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 289.0
HKD3_k127_6682415_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 604.0
HKD3_k127_6684426_0 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 597.0
HKD3_k127_6684426_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 329.0
HKD3_k127_6686231_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 285.0
HKD3_k127_6686231_1 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002024 265.0
HKD3_k127_6715572_0 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 542.0
HKD3_k127_6715572_1 metal-dependent hydrolases with the TIM-barrel fold K07051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 453.0
HKD3_k127_6732393_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.291e-218 679.0
HKD3_k127_6732393_1 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000002403 152.0
HKD3_k127_673363_0 membrane-associated protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 389.0
HKD3_k127_673363_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 358.0
HKD3_k127_6751295_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 478.0
HKD3_k127_6751295_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000007662 190.0
HKD3_k127_6767822_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 374.0
HKD3_k127_6767822_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 358.0
HKD3_k127_6796773_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 2.21e-236 733.0
HKD3_k127_6796773_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.00000000000000000000000000000000000000000000003364 177.0
HKD3_k127_6800159_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002016 255.0
HKD3_k127_680202_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 307.0
HKD3_k127_680202_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000006674 187.0
HKD3_k127_680202_2 Molybdopterin converting factor, small subunit K03636 - - 0.00000000000000000000000000000000000000000000000000009347 188.0
HKD3_k127_6810728_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004556 457.0
HKD3_k127_6813522_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 430.0
HKD3_k127_6813522_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004841 362.0
HKD3_k127_6813522_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 347.0
HKD3_k127_6816916_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 328.0
HKD3_k127_6816916_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002732 269.0
HKD3_k127_6816916_2 - - - - 0.00000000000000000000000000000003561 126.0
HKD3_k127_6816916_3 - - - - 0.000000001492 58.0
HKD3_k127_6819674_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000001315 186.0
HKD3_k127_6819674_1 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.000000000000000000000000000000000000000000000002313 174.0
HKD3_k127_683102_0 PFAM Glycosyl transferase, group 1 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 2.584e-253 783.0
HKD3_k127_683102_1 PFAM Xylose isomerase domain protein TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 522.0
HKD3_k127_683102_2 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 332.0
HKD3_k127_683102_3 Peptidase family C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 318.0
HKD3_k127_683102_4 PAXNEB protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 294.0
HKD3_k127_683102_5 Protein of unknown function (DUF429) K09147 - - 0.0000000000000000000000000000000000000000000000000000000000007817 214.0
HKD3_k127_683102_6 - - - - 0.000000000000000000000000000000000000000001127 157.0
HKD3_k127_683102_7 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000009408 132.0
HKD3_k127_6831848_0 ABC-type transport system involved in multi-copper enzyme maturation, permease K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 449.0
HKD3_k127_6831848_1 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 293.0
HKD3_k127_6836813_0 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 496.0
HKD3_k127_6836813_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 337.0
HKD3_k127_6841320_0 deoxyhypusine monooxygenase activity K01661 - 4.1.3.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 465.0
HKD3_k127_6841320_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005896 251.0
HKD3_k127_6841320_2 - - - - 0.000000000000000000000000000000000000000000000000002162 183.0
HKD3_k127_6843008_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006724 585.0
HKD3_k127_6843008_1 - - - - 0.00006371 46.0
HKD3_k127_6848343_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 406.0
HKD3_k127_6848343_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000002261 114.0
HKD3_k127_6849159_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008296 294.0
HKD3_k127_6849159_1 flavodoxin - - - 0.000000000000000000000000000000000000000000000000000000000001367 210.0
HKD3_k127_6849159_2 MFS_1 like family - - - 0.000000000000000000000000000000000000004214 148.0
HKD3_k127_6868506_0 Glucose / Sorbosone dehydrogenase - - - 9.142e-221 688.0
HKD3_k127_6868506_1 4Fe-4S ferredoxin iron-sulfur binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 448.0
HKD3_k127_6868506_2 2-phosphosulfolactate phosphatase K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 365.0
HKD3_k127_6868506_3 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 329.0
HKD3_k127_6868506_4 - - - - 0.00000000000000000000000000000000000000000000000000000003563 199.0
HKD3_k127_688731_0 4Fe-4S ferredoxin, iron-sulfur binding - - - 1.286e-199 623.0
HKD3_k127_688731_1 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 467.0
HKD3_k127_688731_2 thymidylate kinase K00943 - 2.7.4.9 0.000000000000000009543 84.0
HKD3_k127_6892178_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 1.438e-269 833.0
HKD3_k127_6892178_1 PFAM AIR synthase related protein K07123 - - 0.00000000000003419 74.0
HKD3_k127_6895567_0 Belongs to the NifD NifK NifE NifN family K02592 - - 1.317e-224 702.0
HKD3_k127_6895567_1 Belongs to the NifD NifK NifE NifN family K02587 - - 0.00000000000000000000000000000000000000000000000002128 179.0
HKD3_k127_6896965_0 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005788 463.0
HKD3_k127_6902108_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 439.0
HKD3_k127_6902108_1 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 342.0
HKD3_k127_6902108_2 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 307.0
HKD3_k127_6902800_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 507.0
HKD3_k127_6902800_2 PFAM PUA domain containing protein K07398 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 304.0
HKD3_k127_6902800_3 RNA methylase K07446 - 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000001409 213.0
HKD3_k127_6912317_0 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 2.067e-232 720.0
HKD3_k127_6912317_1 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000000000002421 214.0
HKD3_k127_6912317_2 - - - - 0.000000000000000000000000000000000000000000881 158.0
HKD3_k127_6923211_0 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 451.0
HKD3_k127_6923211_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 296.0
HKD3_k127_6923211_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 291.0
HKD3_k127_6923211_4 PFAM Uncharacterised protein family UPF0066 K01628 - 4.1.2.17 0.00000000000000000000000009973 113.0
HKD3_k127_6923211_5 Glycosyl transferase family group 2 - - - 0.00000000000000000001407 91.0
HKD3_k127_6946688_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1380.0
HKD3_k127_6946688_1 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 - 1.17.1.9 4.904e-276 849.0
HKD3_k127_6946688_2 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 460.0
HKD3_k127_6946688_3 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000002955 95.0
HKD3_k127_6953965_0 This molybdenum-iron protein is part of the nitrogenase complex that catalyzes the key enzymatic reactions in nitrogen fixation K02591 - 1.18.6.1 1.907e-267 826.0
HKD3_k127_6953965_1 Belongs to the NifD NifK NifE NifN family K02587 - - 0.000000000000000000000000000001484 121.0
HKD3_k127_6955565_0 DEAD DEAH box helicase K06877 - - 1.587e-220 684.0
HKD3_k127_6967875_0 Acetyltransferase (GNAT) domain K03817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 379.0
HKD3_k127_6967875_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K03294 - - 0.000000000000000000000000000000000000001333 147.0
HKD3_k127_6967875_2 - - - - 0.000000000000000000002753 95.0
HKD3_k127_6972298_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009962 424.0
HKD3_k127_6972298_1 Molybdenum Cofactor Synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000001905 171.0
HKD3_k127_6972880_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 439.0
HKD3_k127_6972880_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000001632 70.0
HKD3_k127_6987960_0 COG0467 RecA-superfamily ATPases implicated in signal transduction K08482 - - 7.692e-199 622.0
HKD3_k127_6993345_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005146 229.0
HKD3_k127_6993345_1 Fe-S-cluster oxidoreductase - - - 0.0000000000000000000000000000000001025 133.0
HKD3_k127_6993345_2 - - - - 0.00000000000000000000000000001118 117.0
HKD3_k127_6993345_3 - - - - 0.00000000000000305 77.0
HKD3_k127_6999704_0 PAS domain - - - 9.769e-314 972.0
HKD3_k127_7000146_0 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006338 572.0
HKD3_k127_7000146_1 Belongs to the UPF0285 family - - - 0.00000000000000000000000000000000001964 135.0
HKD3_k127_7000146_2 NAD(P)H dehydrogenase (quinone) activity - - - 0.000000000000000000000733 96.0
HKD3_k127_7004902_0 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 305.0
HKD3_k127_7004902_1 general stress protein B in uncultured methanogenic archaeon (Q0W564) - - - 0.00000000000000000000000000000000000000000002033 162.0
HKD3_k127_7010426_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 4.002e-246 762.0
HKD3_k127_7010426_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.000000000000000000000000000000000004221 139.0
HKD3_k127_7010426_2 Beta-Casp domain K07577 - - 0.000000000000000000000004144 102.0
HKD3_k127_7020826_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 359.0
HKD3_k127_7020826_2 - - - - 0.00000003474 55.0
HKD3_k127_7035641_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 480.0
HKD3_k127_7035641_1 - - - - 0.00000000000000000000000000000000000000000000000000000003068 196.0
HKD3_k127_7035641_2 S4 RNA-binding domain K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000107 166.0
HKD3_k127_7052667_0 KH, type 1, domain K07041 - - 9.893e-315 964.0
HKD3_k127_7052667_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 407.0
HKD3_k127_7052667_2 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000003632 179.0
HKD3_k127_7052667_3 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000001199 91.0
HKD3_k127_7060164_0 ATPases associated with a variety of cellular activities K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 435.0
HKD3_k127_7060164_1 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 415.0
HKD3_k127_7060164_2 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.000000000000000000000000000000000000000000000000003272 191.0
HKD3_k127_7060164_3 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.000000000002758 75.0
HKD3_k127_7060810_0 - - - - 1.563e-226 704.0
HKD3_k127_7082107_0 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000001451 234.0
HKD3_k127_7082107_1 ATP hydrolysis coupled proton transport K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000004338 106.0
HKD3_k127_7084435_0 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 583.0
HKD3_k127_7084435_1 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 469.0
HKD3_k127_7084435_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 429.0
HKD3_k127_7086822_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 340.0
HKD3_k127_7086822_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000004824 250.0
HKD3_k127_7086822_2 Histidine kinase K14986 - 2.7.13.3 0.000000001141 70.0
HKD3_k127_7092704_0 Sigma factor PP2C-like phosphatases K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 433.0
HKD3_k127_7104505_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004803 259.0
HKD3_k127_7104505_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000002456 79.0
HKD3_k127_7108440_0 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 602.0
HKD3_k127_7108440_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 377.0
HKD3_k127_7108440_2 V4R K07013 - - 0.00000000000000000000000000000000000000000000003794 169.0
HKD3_k127_7116876_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 282.0
HKD3_k127_7116876_2 Peptidase s1 and s6 chymotrypsin hap K08372 - - 0.0003381 48.0
HKD3_k127_7177390_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 383.0
HKD3_k127_7180966_0 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 423.0
HKD3_k127_7180966_1 Uncharacterized protein conserved in archaea (DUF2226) K02039,K09718 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008407 300.0
HKD3_k127_7180966_2 Roadblock LC7 K07131 - - 0.0000000000006746 68.0
HKD3_k127_7190849_0 N-terminal domain of (some) glycogen debranching enzymes - - - 1.898e-260 803.0
HKD3_k127_7193361_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.98e-258 802.0
HKD3_k127_7193361_1 - - - - 0.000000002091 60.0
HKD3_k127_721111_0 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 475.0
HKD3_k127_721111_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000009051 171.0
HKD3_k127_721111_2 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000000001087 104.0
HKD3_k127_7215775_0 Sodium:alanine symporter family K03310 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 456.0
HKD3_k127_7215775_1 - - - - 0.000000000000000000004305 94.0
HKD3_k127_7227527_0 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 368.0
HKD3_k127_7227527_1 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000002021 189.0
HKD3_k127_7233024_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 7.428e-281 864.0
HKD3_k127_7233024_1 KEOPS complex Cgi121-like subunit K09119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 308.0
HKD3_k127_7233024_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000001811 194.0
HKD3_k127_7233024_3 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000003091 107.0
HKD3_k127_7239325_0 Histidine kinase-like ATPases - - - 1.053e-268 831.0
HKD3_k127_7239325_1 Subtilase family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 578.0
HKD3_k127_7239325_2 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 397.0
HKD3_k127_7239325_3 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002342 269.0
HKD3_k127_7274700_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 512.0
HKD3_k127_7274700_1 PFAM TrkA-N domain protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001384 262.0
HKD3_k127_7274700_2 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000000000000000000000000000000000000001274 217.0
HKD3_k127_7276022_0 COG1309 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 394.0
HKD3_k127_7276022_1 Radical SAM domain - - - 0.000000000000000000000000000000000000007748 145.0
HKD3_k127_7277010_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1437.0
HKD3_k127_7277010_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 466.0
HKD3_k127_7277010_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 358.0
HKD3_k127_7277010_3 transcription termination protein NusA K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 293.0
HKD3_k127_7277010_4 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 292.0
HKD3_k127_7277010_5 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000000000000000000000000004223 112.0
HKD3_k127_7293514_1 - - - - 0.00000000000000000000000000000000000000000000007546 169.0
HKD3_k127_7293514_2 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000001866 164.0
HKD3_k127_7299702_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000002271 171.0
HKD3_k127_7299702_1 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000001054 86.0
HKD3_k127_7299702_2 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000000000000002952 81.0
HKD3_k127_731453_0 PFAM Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 473.0
HKD3_k127_731453_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000003101 108.0
HKD3_k127_7318068_0 WD domain, G-beta repeat - - - 1.357e-199 625.0
HKD3_k127_7318068_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 486.0
HKD3_k127_7318068_2 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.000000000000000000000000000001826 120.0
HKD3_k127_7318068_3 - - - - 0.00000000000000000003283 89.0
HKD3_k127_7322430_0 phosphoesterase RecJ domain protein - - - 7.452e-215 670.0
HKD3_k127_7323804_0 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 312.0
HKD3_k127_7323804_1 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000000000000000001144 118.0
HKD3_k127_7323804_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000001866 82.0
HKD3_k127_7327354_0 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005327 324.0
HKD3_k127_7327354_1 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000002329 180.0
HKD3_k127_7327460_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 360.0
HKD3_k127_7327460_1 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000000000008635 98.0
HKD3_k127_7339560_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 481.0
HKD3_k127_7339560_1 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 368.0
HKD3_k127_7357697_0 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000004507 123.0
HKD3_k127_7357697_1 Protein of unknown function DUF58 - - - 0.000000004149 59.0
HKD3_k127_7369670_0 - - - - 4.808e-220 683.0
HKD3_k127_7385158_0 Major facilitator superfamily - - - 1.118e-205 642.0
HKD3_k127_7388563_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 2.037e-275 847.0
HKD3_k127_7388563_1 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 543.0
HKD3_k127_7388563_2 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 496.0
HKD3_k127_7388563_3 Coenzyme F420-reducing hydrogenase, delta subunit K00442 - - 0.000000000000000000000000000000000000000000000004379 178.0
HKD3_k127_7423238_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.065e-246 763.0
HKD3_k127_7423238_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000002074 207.0
HKD3_k127_7433436_0 Flavin containing amine oxidoreductase - - - 1.409e-221 689.0
HKD3_k127_7433436_1 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K11181 GO:0003674,GO:0003824,GO:0005575,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016002,GO:0016020,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0044237,GO:0050311,GO:0055114 1.8.99.5 0.00000000000000000000000000001298 119.0
HKD3_k127_7442877_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 550.0
HKD3_k127_7442877_1 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005943 441.0
HKD3_k127_7450192_0 Permease family K06901 - - 5.387e-261 807.0
HKD3_k127_7457451_0 Methyl-viologen-reducing hydrogenase, delta subunit K22480 - 1.8.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 583.0
HKD3_k127_7457451_1 Cysteine-rich domain K03389,K22481 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 529.0
HKD3_k127_747704_0 Belongs to the GbsR family K22109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007375 286.0
HKD3_k127_747704_1 - - - - 0.00000000000000000000000000000000000000000000000001056 182.0
HKD3_k127_747704_2 - - - - 0.00000000000000000000000000000000000000000000002814 175.0
HKD3_k127_747704_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000002584 128.0
HKD3_k127_747704_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000009565 69.0
HKD3_k127_7481229_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0 1044.0
HKD3_k127_7481229_1 COG0438 Glycosyltransferase - - - 1.034e-232 722.0
HKD3_k127_7481229_2 ferredoxin iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 367.0
HKD3_k127_7481229_3 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 283.0
HKD3_k127_7481229_4 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.000000000000000000000001946 104.0
HKD3_k127_7498244_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 375.0
HKD3_k127_7498244_1 - - - - 0.000000000000000000002201 94.0
HKD3_k127_7503901_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 332.0
HKD3_k127_7503901_1 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000000000000000000000000000005567 229.0
HKD3_k127_7503901_2 Binds to the 23S rRNA K02896 - - 0.0000000000000000000000000000000000000003258 152.0
HKD3_k127_7503901_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.0000000000000000000000000000000000002496 140.0
HKD3_k127_7503901_4 - - - - 0.00000000000000000000000000000194 121.0
HKD3_k127_7503901_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000002228 69.0
HKD3_k127_7511409_0 ABC-type multidrug transport system, ATPase component K01990 - - 7.112e-252 781.0
HKD3_k127_7511409_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000003803 162.0
HKD3_k127_7523694_0 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 451.0
HKD3_k127_7523694_1 Ribbon-helix-helix protein, copG family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 360.0
HKD3_k127_7523694_2 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis - - - 0.0000000000000000000000000000007205 123.0
HKD3_k127_7538634_0 PAS domain - - - 8.378e-227 706.0
HKD3_k127_7542336_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 4.101e-198 620.0
HKD3_k127_7542336_1 NUDIX domain K03574 - 3.6.1.55 0.000000000000008361 74.0
HKD3_k127_7550561_0 Ferrous iron transport B domain protein K04759 - - 0.0 1164.0
HKD3_k127_7550561_1 Glycosyl transferase family 21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 448.0
HKD3_k127_7550561_2 FeoA K03709 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 421.0
HKD3_k127_7550561_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 327.0
HKD3_k127_7550561_4 pfam nmd3 K07562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001631 246.0
HKD3_k127_7552260_0 PFAM Cation K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 552.0
HKD3_k127_7552260_1 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002447 293.0
HKD3_k127_7552314_1 Endonuclease Exonuclease Phosphatase - - - 0.0006451 50.0
HKD3_k127_7573152_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.664e-318 975.0
HKD3_k127_7573152_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002293 275.0
HKD3_k127_757980_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000001682 213.0
HKD3_k127_757980_1 ABC-type cobalt transport system, permease component - - - 0.000000000000000000002583 98.0
HKD3_k127_7580995_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02472 - 1.1.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 348.0
HKD3_k127_7580995_1 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000005416 207.0
HKD3_k127_7582849_0 PFAM Xylose isomerase domain protein TIM barrel - - - 4.743e-209 651.0
HKD3_k127_7595627_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 7.066e-256 790.0
HKD3_k127_7618120_0 Sulfide dehydrogenase (Flavoprotein) subunit SudB K00528,K02823 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 517.0
HKD3_k127_7618120_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000842 210.0
HKD3_k127_7619615_0 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 559.0
HKD3_k127_7619615_1 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 531.0
HKD3_k127_763648_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 5e-324 996.0
HKD3_k127_763648_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 494.0
HKD3_k127_763648_2 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 400.0
HKD3_k127_763648_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 291.0
HKD3_k127_763648_4 - - - - 0.000000000000000000000000000000000000000000000003797 175.0
HKD3_k127_7661361_0 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000855 232.0
HKD3_k127_7661361_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000001598 168.0
HKD3_k127_7673004_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 1.3e-255 790.0
HKD3_k127_7673004_1 - - - - 0.000000000000000000000001545 103.0
HKD3_k127_7677729_0 TIGRFAM small GTP-binding protein K06944 - - 2.659e-218 679.0
HKD3_k127_7680384_0 HTH-type transcriptional regulatory protein K07728 - - 3.619e-198 619.0
HKD3_k127_7680384_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 461.0
HKD3_k127_7685988_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 1.796e-216 671.0
HKD3_k127_7700701_0 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 354.0
HKD3_k127_7700701_1 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 285.0
HKD3_k127_7700701_2 PFAM Cobalt transport protein K16785 - - 0.00000000000000000004264 93.0
HKD3_k127_771177_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 1.739e-248 769.0
HKD3_k127_771177_1 Subtilase family K17734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 299.0
HKD3_k127_771177_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 298.0
HKD3_k127_771177_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000058 282.0
HKD3_k127_7713298_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006265 487.0
HKD3_k127_7713298_1 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000000001658 79.0
HKD3_k127_7714247_0 Flavodoxin domain K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 409.0
HKD3_k127_7714247_1 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007005 326.0
HKD3_k127_7714247_2 PA14 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 309.0
HKD3_k127_7714247_3 Archaeal Type IV pilin, N-terminal K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007615 276.0
HKD3_k127_7714247_4 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000001502 73.0
HKD3_k127_7715603_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 2.454e-267 824.0
HKD3_k127_7715603_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.0007284 46.0
HKD3_k127_7717115_0 amino acid K03294 - - 0.0 1086.0
HKD3_k127_7717115_1 mechanosensitive ion channel K03442,K07454 - - 0.00000000000000000000000000000000000000000000000000000000000000001569 224.0
HKD3_k127_7717115_2 - - - - 0.00000000000000000000000000000000000000000000000000004542 193.0
HKD3_k127_7717115_3 - - - - 0.0000000000000000000000000000002466 125.0
HKD3_k127_772974_0 associated with various cellular activities K03695,K03696 - - 0.0 1435.0
HKD3_k127_772974_1 Protein tyrosine kinase - - - 0.0 1133.0
HKD3_k127_772974_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 341.0
HKD3_k127_772974_3 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 320.0
HKD3_k127_772974_4 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00002042 46.0
HKD3_k127_7742333_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 7.429e-229 722.0
HKD3_k127_7742333_1 FecCD transport family K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 524.0
HKD3_k127_7749382_0 PFAM AAA ATPase central domain protein - - - 1.96e-272 839.0
HKD3_k127_7749382_1 COG1522 Transcriptional regulators K03718 - - 0.000000000000000000000000000000000000000000000000000000006166 199.0
HKD3_k127_7749382_2 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000000000004866 110.0
HKD3_k127_7755178_0 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 359.0
HKD3_k127_7755178_1 malonyl CoA-acyl carrier protein transacylase K00645 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.00000000000000000000000000000003196 129.0
HKD3_k127_7755178_2 Domain of unknown function (DUF4893) - - - 0.00000000000005077 73.0
HKD3_k127_7761982_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.263e-197 617.0
HKD3_k127_7761982_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001007 275.0
HKD3_k127_7765912_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 9.874e-239 739.0
HKD3_k127_7765912_1 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 377.0
HKD3_k127_7765912_2 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000001373 218.0
HKD3_k127_7765912_3 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000002089 71.0
HKD3_k127_7780083_0 UPF0126 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 341.0
HKD3_k127_7780083_1 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002472 236.0
HKD3_k127_7780083_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001883 228.0
HKD3_k127_7784778_0 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000004134 268.0
HKD3_k127_7784778_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000006228 176.0
HKD3_k127_7795222_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 451.0
HKD3_k127_7795222_1 COG1668 ABC-type Na efflux pump, permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 303.0
HKD3_k127_7796656_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0 1291.0
HKD3_k127_7796656_1 Protein of unknown function (DUF1614) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 402.0
HKD3_k127_7796656_2 Hsp20/alpha crystallin family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 308.0
HKD3_k127_7796656_3 PFAM PRC-barrel domain - - - 0.0000000000000000000000000000000000000000000002412 168.0
HKD3_k127_7796656_4 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000002344 114.0
HKD3_k127_7797275_0 Belongs to the Protein of K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 439.0
HKD3_k127_7797275_1 TIGRFAM PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001607 223.0
HKD3_k127_7798365_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 4.556e-274 849.0
HKD3_k127_7798365_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 4.69e-266 822.0
HKD3_k127_7798365_2 DNA-binding transcription factor activity - - - 1.923e-231 721.0
HKD3_k127_7798365_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.065e-201 634.0
HKD3_k127_7798365_4 Haloacid dehalogenase-like hydrolase K01838 - 5.4.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 414.0
HKD3_k127_7798365_5 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000003075 184.0
HKD3_k127_7798365_6 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.0000000000000000000000000008997 112.0
HKD3_k127_7798365_7 protein conserved in archaea - - - 0.0000000000000000000000001285 106.0
HKD3_k127_7798365_8 protein conserved in archaea - - - 0.000000000000000001409 85.0
HKD3_k127_7814499_0 Amino acid ABC transporter substrate-binding protein, PAAT family K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 541.0
HKD3_k127_7814499_1 amino acid ABC transporter K02029 - - 0.0000000000000000000000000000000000000000007825 157.0
HKD3_k127_7814499_2 - - - - 0.0000000000000000000000000008455 112.0
HKD3_k127_7829074_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 280.0
HKD3_k127_7829074_1 - - - - 0.000000000000000000000000000000000000000000000000000000000005081 209.0
HKD3_k127_7829074_2 - - - - 0.00000000000000000000000000000000000000000000000000000000007777 207.0
HKD3_k127_7829074_3 - - - - 0.000000000000000007257 82.0
HKD3_k127_7829074_4 - - - - 0.0000000001455 62.0
HKD3_k127_7835649_0 Domain of unknown function (DUF4932) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 302.0
HKD3_k127_7835649_1 PFAM TM2 domain containing protein K03686 - - 0.000000000000000000000000000000000000000000000000000000000005889 207.0
HKD3_k127_7835649_2 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000251 146.0
HKD3_k127_784737_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000000000000000000000000000000000000001585 225.0
HKD3_k127_784737_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000001983 131.0
HKD3_k127_7849797_0 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000001442 171.0
HKD3_k127_7849797_1 ATP-dependent peptidase activity K01338,K04076,K04770,K06915 - 3.4.21.53 0.00001866 48.0
HKD3_k127_7860510_0 to orf2, orf11, orf12, orf13, orf14, orf15 of fosmid clone 4B7mr3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 386.0
HKD3_k127_7860510_1 to orf2, orf11, orf12, orf13, orf14, orf15 of fosmid clone 4B7mr3 - - - 0.000000000000000216 83.0
HKD3_k127_7860788_0 to orf3 of fosmid clone 4B7mr3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 395.0
HKD3_k127_786777_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1016.0
HKD3_k127_7887973_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 482.0
HKD3_k127_7887973_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 332.0
HKD3_k127_7887973_2 pyridoxamine 5'-phosphate oxidase-related FMN-binding K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 297.0
HKD3_k127_7924721_0 Protein of unknown function (DUF354) K09726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001917 278.0
HKD3_k127_7924721_1 to orf2, orf11, orf12, orf13, orf14, orf15 of fosmid clone 4B7mr3 - - - 0.0000000000000000000000000000000000000000007361 160.0
HKD3_k127_7930200_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.874e-207 646.0
HKD3_k127_7930200_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 332.0
HKD3_k127_7930200_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000006766 166.0
HKD3_k127_7930200_3 Heavy-metal-associated domain K01533,K07213,K07496,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000003271 148.0
HKD3_k127_7930200_4 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000000000001465 118.0
HKD3_k127_7930200_5 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.000000001212 59.0
HKD3_k127_793530_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1111.0
HKD3_k127_793530_1 - - - - 0.0000000000002427 71.0
HKD3_k127_7952293_0 Protein of unknown function (DUF521) K09123 - - 6.01e-257 794.0
HKD3_k127_7952293_1 PFAM chaperonin Cpn60 TCP-1 K22447 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 410.0
HKD3_k127_7966929_0 Integral membrane protein DUF92 - - - 2.856e-236 734.0
HKD3_k127_7966929_1 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.0000000000000000001718 97.0
HKD3_k127_7969491_0 PFAM amidohydrolase - - - 3.848e-212 661.0
HKD3_k127_7969491_1 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 542.0
HKD3_k127_7969491_2 Universal stress protein family - - - 0.000000000000000000000000000003359 124.0
HKD3_k127_7969491_3 - - - - 0.00000000000000000000000007261 108.0
HKD3_k127_7969491_4 Involved in protein export. The function of the beta subunit is - GO:0003674,GO:0005085,GO:0005086,GO:0005488,GO:0005515,GO:0008150,GO:0019899,GO:0051020,GO:0065007,GO:0065009,GO:0098772 - 0.0000000000000000000000006681 105.0
HKD3_k127_7974939_0 Belongs to the UPF0305 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004608 395.0
HKD3_k127_7974939_1 Protein of unknown function (DUF1453) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007159 240.0
HKD3_k127_7974939_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000006368 160.0
HKD3_k127_7974939_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000001831 90.0
HKD3_k127_7978891_0 metal-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 285.0
HKD3_k127_7978891_1 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000008408 157.0
HKD3_k127_7978891_2 - - - - 0.000000000000000000000000000000000000006864 151.0
HKD3_k127_7978891_3 - - - - 0.0000000000000000000000000000000000001767 143.0
HKD3_k127_7989307_0 MgtC family - - - 3.559e-231 719.0
HKD3_k127_7989307_1 Phosphoribosyl transferase domain K07100 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 391.0
HKD3_k127_7989307_2 - - - - 0.000000000000000007429 87.0
HKD3_k127_7989307_3 N-terminal domain of (some) glycogen debranching enzymes - - - 0.0000000000000007709 77.0
HKD3_k127_7996695_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 582.0
HKD3_k127_7996695_1 ABC-type Na efflux pump, permease K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008955 458.0
HKD3_k127_7996695_2 ABC-type Na efflux pump, permease K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 416.0
HKD3_k127_7996695_3 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007298 244.0
HKD3_k127_8007197_0 TRAP transporter solute receptor, TAXI family K07080 - - 6.544e-202 631.0
HKD3_k127_8007197_1 Domain of unknown function (DUF1850) - - - 0.0000000000000001436 80.0
HKD3_k127_8007937_0 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000001361 245.0
HKD3_k127_8007937_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000001032 64.0
HKD3_k127_8010692_0 signal transduction protein with CBS domains K07744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 452.0
HKD3_k127_8010692_1 Pyridoxamine 5'-phosphate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004843 260.0
HKD3_k127_8010692_2 - - - - 0.000000000000000000000000000000000000000000001426 171.0
HKD3_k127_801607_0 Pas domain - - - 1.156e-318 984.0
HKD3_k127_801607_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000001573 90.0
HKD3_k127_8017065_0 Periplasmic copper-binding protein (NosD) - - - 0.0 1640.0
HKD3_k127_8017065_1 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 479.0
HKD3_k127_8024937_0 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001109 284.0
HKD3_k127_8028440_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 346.0
HKD3_k127_8028440_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 328.0
HKD3_k127_8030141_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.046e-255 787.0
HKD3_k127_8030141_1 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000000000000000000000000000000000000007102 169.0
HKD3_k127_8030141_2 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000000000000000000001974 125.0
HKD3_k127_803482_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 463.0
HKD3_k127_803482_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 437.0
HKD3_k127_803482_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 378.0
HKD3_k127_803482_3 COG2041 Sulfite oxidase and related enzymes K16925 - - 0.000000000000000000000000000000000000000003029 156.0
HKD3_k127_803482_4 lipopolysaccharide core region biosynthetic process - - - 0.0000000000000000005958 95.0
HKD3_k127_8035403_0 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 377.0
HKD3_k127_8035403_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005196 252.0
HKD3_k127_8049722_0 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 577.0
HKD3_k127_8049722_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000003809 69.0
HKD3_k127_8055829_0 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 492.0
HKD3_k127_8055829_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000001925 209.0
HKD3_k127_807320_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 1.512e-234 727.0
HKD3_k127_807320_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 398.0
HKD3_k127_807320_2 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000000000000000000003702 93.0
HKD3_k127_8080980_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007553 341.0
HKD3_k127_8080980_1 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 313.0
HKD3_k127_8080980_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000000000001692 262.0
HKD3_k127_8080980_3 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000002721 143.0
HKD3_k127_8087197_0 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 4.94e-197 616.0
HKD3_k127_8087197_1 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 518.0
HKD3_k127_8087197_2 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.000000000006338 65.0
HKD3_k127_8100945_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 577.0
HKD3_k127_8114845_0 amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 389.0
HKD3_k127_8114845_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 294.0
HKD3_k127_8114845_2 PFAM PEGA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009926 245.0
HKD3_k127_8118522_0 amino acid K16263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 550.0
HKD3_k127_8118522_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 364.0
HKD3_k127_8118522_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 316.0
HKD3_k127_8118522_3 LysE type translocator K06895 - - 0.000000000000000000000000000000000000000000000000000000000000000007533 230.0
HKD3_k127_8118522_4 MazG nucleotide pyrophosphohydrolase domain - - - 0.0000000000000000000000000000000000000000000000000000278 188.0
HKD3_k127_8118522_5 Stage II sporulation protein M - - - 0.000000000000000000000000000000000000000000000001821 174.0
HKD3_k127_8132624_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.093e-211 661.0
HKD3_k127_8132624_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 287.0
HKD3_k127_8133067_0 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009704 531.0
HKD3_k127_8133067_1 oligoendopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 339.0
HKD3_k127_8138699_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000002128 225.0
HKD3_k127_8153095_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000153 265.0
HKD3_k127_8153095_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000001159 101.0
HKD3_k127_815460_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 314.0
HKD3_k127_815460_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006117 271.0
HKD3_k127_815460_2 - - - - 0.000000000000000000000000000000000000003999 146.0
HKD3_k127_815460_3 - - - - 0.0000000000000000000000000000000000008597 143.0
HKD3_k127_815460_4 2-phosphosulfolactate phosphatase K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000001176 94.0
HKD3_k127_8162319_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 346.0
HKD3_k127_8162319_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001309 263.0
HKD3_k127_8174219_0 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 314.0
HKD3_k127_8174219_1 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K06976 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 289.0
HKD3_k127_8174219_2 - - - - 0.000000000000000000000328 97.0
HKD3_k127_8180129_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 468.0
HKD3_k127_8180129_1 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 343.0
HKD3_k127_8180129_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001559 261.0
HKD3_k127_8180129_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003393 226.0
HKD3_k127_8196370_0 acid binding OB-fold tRNA helicase-type K07463 - - 0.0 1339.0
HKD3_k127_8196370_1 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001325 269.0
HKD3_k127_820100_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 2.324e-227 706.0
HKD3_k127_820100_1 protein-glutamine gamma-glutamyltransferase activity K00686 - 2.3.2.13 2.049e-196 615.0
HKD3_k127_820100_2 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000005489 168.0
HKD3_k127_820100_3 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.000000000000000000002311 93.0
HKD3_k127_820207_0 Holliday junction DNA helicase ruvB C-terminus K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 524.0
HKD3_k127_820207_1 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 353.0
HKD3_k127_820207_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 306.0
HKD3_k127_820672_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 357.0
HKD3_k127_820672_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 302.0
HKD3_k127_822144_0 - K16906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 430.0
HKD3_k127_822144_1 COG1131 ABC-type multidrug transport system ATPase component K16907 - - 0.000000000000000000000000000000000000000001366 156.0
HKD3_k127_822144_2 - K16905,K16906 - - 0.000000000000000000000000001531 111.0
HKD3_k127_8225083_0 PFAM ABC transporter K00400 - - 1.154e-242 750.0
HKD3_k127_8225083_1 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 516.0
HKD3_k127_8226020_0 DUF3160 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 586.0
HKD3_k127_8226020_1 - - - - 0.00004487 45.0
HKD3_k127_822695_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 417.0
HKD3_k127_8243676_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 569.0
HKD3_k127_8243676_1 N-6 DNA methylase K03427,K07317 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 479.0
HKD3_k127_8258720_0 DRTGG domain K06873 - - 1.818e-220 685.0
HKD3_k127_8258720_1 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000000000000000000000381 265.0
HKD3_k127_8258720_2 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000008603 107.0
HKD3_k127_8273166_0 ACT domain K09707 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004379 267.0
HKD3_k127_8273166_1 ferredoxin iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008539 248.0
HKD3_k127_8273166_2 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000005867 123.0
HKD3_k127_8280330_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 564.0
HKD3_k127_8280330_1 - - - - 0.000000000001348 67.0
HKD3_k127_8282848_0 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 400.0
HKD3_k127_8282848_1 tRNA synthetases class II (A) K01872 - 6.1.1.7 0.000000000000000000000000000000000000000005602 155.0
HKD3_k127_8290908_0 Tetratricopeptide repeat - - - 6.508e-249 769.0
HKD3_k127_8290908_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 316.0
HKD3_k127_8294697_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 7.906e-248 765.0
HKD3_k127_829905_0 Pas domain s-box - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 414.0
HKD3_k127_8317605_0 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 346.0
HKD3_k127_8317605_1 - - - - 0.00000000000000000000001846 104.0
HKD3_k127_8320226_0 membrane-associated protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 599.0
HKD3_k127_8320226_1 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 524.0
HKD3_k127_8324357_0 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 588.0
HKD3_k127_8328082_0 Protein of unknown function (DUF3887) K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006338 259.0
HKD3_k127_8328082_1 PFAM PEGA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003625 238.0
HKD3_k127_8328082_2 - - - - 0.00000000000000000000000000000000000000000000000000006421 188.0
HKD3_k127_8329241_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001022 242.0
HKD3_k127_8329241_1 - - - - 0.00000000000000000000000000000000000000000000000000005742 188.0
HKD3_k127_8329577_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 3.908e-211 660.0
HKD3_k127_8338276_0 Dihydrouridine synthase (Dus) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 578.0
HKD3_k127_8338276_1 PFAM triphosphoribosyl-dephospho-CoA protein K05966 - 2.4.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005241 268.0
HKD3_k127_835129_0 PFAM Radical SAM domain protein K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 582.0
HKD3_k127_835129_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000004392 73.0
HKD3_k127_835406_0 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005956 385.0
HKD3_k127_835406_1 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000000000001321 169.0
HKD3_k127_835406_2 - - - - 0.0000000000000000000000000000001572 124.0
HKD3_k127_835406_3 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000004492 119.0
HKD3_k127_8365350_0 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 481.0
HKD3_k127_8365350_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.00000000000000000000000000004925 115.0
HKD3_k127_8366208_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 534.0
HKD3_k127_8366208_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000008165 156.0
HKD3_k127_8377767_0 KH, type 1, domain K07041 - - 1.752e-208 649.0
HKD3_k127_838989_0 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 458.0
HKD3_k127_838989_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 290.0
HKD3_k127_838989_2 - - - - 0.0000000000000202 82.0
HKD3_k127_841756_0 ADP-ribosylation factor family K06945 - - 0.0 1001.0
HKD3_k127_841756_1 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 3.189e-261 805.0
HKD3_k127_841756_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008071 407.0
HKD3_k127_841756_3 transcriptional regulators K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000003225 228.0
HKD3_k127_8430061_0 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 351.0
HKD3_k127_8430061_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000003944 178.0
HKD3_k127_8430061_2 - - - - 0.000000000000000000003546 93.0
HKD3_k127_8442206_1 - - - - 0.000000000000000000000000000000002968 130.0
HKD3_k127_8443596_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 358.0
HKD3_k127_8443596_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009379 299.0
HKD3_k127_8443596_2 hydrolase K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000001911 212.0
HKD3_k127_84515_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 572.0
HKD3_k127_84515_1 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 405.0
HKD3_k127_84515_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 355.0
HKD3_k127_84515_3 PFAM Ribosomal protein K02912 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 336.0
HKD3_k127_84515_4 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 296.0
HKD3_k127_84515_5 TIGRFAM ribosomal protein L30P K02907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 302.0
HKD3_k127_84515_6 binds to the 23S rRNA K02885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002505 263.0
HKD3_k127_845668_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0 1045.0
HKD3_k127_8485364_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 546.0
HKD3_k127_8485364_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000001468 115.0
HKD3_k127_848782_0 AAA-like domain K06915 - - 7.265e-275 846.0
HKD3_k127_848782_1 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000000000000000000000003466 226.0
HKD3_k127_848782_2 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000000000000000000000000000000001585 188.0
HKD3_k127_8488944_0 Nucleotidyltransferase domain K07073 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 430.0
HKD3_k127_8488944_1 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 348.0
HKD3_k127_8488944_2 Transcriptional regulator, TrmB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002741 244.0
HKD3_k127_8488944_3 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000000000000000000000000000002145 203.0
HKD3_k127_8490961_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.255e-286 879.0
HKD3_k127_8490961_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 561.0
HKD3_k127_8490961_2 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000008949 82.0
HKD3_k127_8507776_0 COG1472 Beta-glucosidase-related glycosidases K05349 - 3.2.1.21 5.658e-276 852.0
HKD3_k127_8507776_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000007807 129.0
HKD3_k127_8512791_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000006149 208.0
HKD3_k127_8512791_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000001698 206.0
HKD3_k127_8512791_2 - - - - 0.0000007529 52.0
HKD3_k127_8527073_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004465 571.0
HKD3_k127_8527073_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 428.0
HKD3_k127_8527073_2 Nuclease-related domain - - - 0.00000000000002401 73.0
HKD3_k127_8537615_0 Binding-protein-dependent transport system inner membrane component K02033 - - 3.4e-211 657.0
HKD3_k127_8537615_1 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006557 549.0
HKD3_k127_8548503_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 9.367e-282 869.0
HKD3_k127_8548503_1 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000001354 248.0
HKD3_k127_8548503_2 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000003413 199.0
HKD3_k127_8548503_3 Belongs to the UPF0235 family K09131 - - 0.000000000000000000000000000000000000000000000000004757 183.0
HKD3_k127_8559310_0 Winged helix DNA-binding domain - - - 8.916e-212 663.0
HKD3_k127_8559310_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000002354 237.0
HKD3_k127_8559310_2 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000000000000000000009442 136.0
HKD3_k127_8559310_3 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.00000000002808 64.0
HKD3_k127_8565752_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 2.983e-227 705.0
HKD3_k127_8565752_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000004661 109.0
HKD3_k127_8570423_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 411.0
HKD3_k127_8570423_1 Polynucleotide kinase that can phosphorylate the 5'- hydroxyl groups of both single-stranded RNA (ssRNA) and single- stranded DNA (ssDNA). Exhibits a strong preference for ssRNA K06947 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019205,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0051731,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000003516 198.0
HKD3_k127_857639_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1020.0
HKD3_k127_857639_1 - - - - 0.00000000000000000000000000001438 120.0
HKD3_k127_8600019_0 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000248 247.0
HKD3_k127_8600019_1 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000001356 173.0
HKD3_k127_8600019_2 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000006885 106.0
HKD3_k127_8605949_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 362.0
HKD3_k127_8605949_1 Belongs to the peptidase S16 family K06870 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 298.0
HKD3_k127_8605949_2 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000003286 83.0
HKD3_k127_8606301_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 587.0
HKD3_k127_8609911_0 Cysteine-rich domain - - - 2.077e-196 614.0
HKD3_k127_8625333_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.243e-203 634.0
HKD3_k127_8625333_1 - - - - 0.0000000000000000000000007732 105.0
HKD3_k127_8625333_2 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000002864 83.0
HKD3_k127_8627429_0 acid phosphatase activity - - - 5.529e-257 797.0
HKD3_k127_8627429_1 COGs COG1277 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000002363 219.0
HKD3_k127_8631489_0 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 333.0
HKD3_k127_8631489_1 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.00000000007709 66.0
HKD3_k127_8638059_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 6.801e-261 812.0
HKD3_k127_8638059_1 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.00000000000000007102 80.0
HKD3_k127_8640720_0 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 450.0
HKD3_k127_8640720_1 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 422.0
HKD3_k127_8640720_2 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000928 334.0
HKD3_k127_8651572_0 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 376.0
HKD3_k127_8651572_1 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000007297 195.0
HKD3_k127_8661149_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 3.425e-223 692.0
HKD3_k127_8676510_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.925e-212 660.0
HKD3_k127_8691432_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005444 243.0
HKD3_k127_8691432_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004287 243.0
HKD3_k127_8716631_0 Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 466.0
HKD3_k127_8716631_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 334.0
HKD3_k127_8716631_2 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000001517 162.0
HKD3_k127_8728378_0 4Fe-4S dicluster domain K14091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 295.0
HKD3_k127_8728378_1 - - - - 0.00000000000000000000000000000000000000000000000000001182 190.0
HKD3_k127_8728378_2 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14090 - - 0.00000000000000000000000000000000000007139 141.0
HKD3_k127_8728378_3 PFAM response regulator receiver - - - 0.00004487 45.0
HKD3_k127_8729662_0 tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 524.0
HKD3_k127_8734200_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 410.0
HKD3_k127_8734200_1 subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase contains the PP-loop ATPase domain K07585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 358.0
HKD3_k127_8734200_2 Belongs to the PDCD5 family K06875 - - 0.000000000000000000000000000000000000000000000000000005051 192.0
HKD3_k127_8734200_3 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.00000000000000000000000000000000000003054 143.0
HKD3_k127_8734200_4 Ribosomal proteins 50S-L18Ae/60S-L20/60S-L18A K02944 - - 0.000000000000000000000000003544 110.0
HKD3_k127_8734200_5 structural constituent of ribosome K02924 - - 0.00000000000000000000008093 104.0
HKD3_k127_8734200_6 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.00000007973 53.0
HKD3_k127_8749540_0 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 1.115e-219 682.0
HKD3_k127_8749540_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000007851 136.0
HKD3_k127_8749540_2 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000004143 130.0
HKD3_k127_8760593_0 Ion transport protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 378.0
HKD3_k127_8760593_1 PAS fold - - - 0.000000000000000000000000000000000008685 136.0
HKD3_k127_8779562_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 - 2.3.1.234 5.383e-202 629.0
HKD3_k127_8779562_1 RIO1 family K08851 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000318 189.0
HKD3_k127_8816888_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 484.0
HKD3_k127_8816888_1 by modhmm - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009747 410.0
HKD3_k127_8816888_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K09163 - - 0.000000000000000000000000000000000000004177 153.0
HKD3_k127_8816957_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 605.0
HKD3_k127_8816957_1 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 292.0
HKD3_k127_8840846_0 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 274.0
HKD3_k127_8840846_1 PP-loop domain protein K06864 - - 0.00000000000000000000000000001885 120.0
HKD3_k127_8841484_0 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 447.0
HKD3_k127_8841484_1 response regulator, receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001904 243.0
HKD3_k127_8841484_3 protein conserved in archaea - - - 0.00000001682 57.0
HKD3_k127_885595_0 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 351.0
HKD3_k127_885595_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000000000000000000000000000000000000001568 203.0
HKD3_k127_8869494_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.295e-208 651.0
HKD3_k127_8879606_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.254e-253 784.0
HKD3_k127_8888828_0 PFAM glycosyl transferase, group 1 - - - 3.253e-257 793.0
HKD3_k127_8888828_1 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000001078 135.0
HKD3_k127_8899911_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001234 258.0
HKD3_k127_8899911_1 Peptidase family M23 - - - 0.0000000000000000000000000000005532 125.0
HKD3_k127_8900066_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 548.0
HKD3_k127_8900066_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000001606 150.0
HKD3_k127_8907332_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 7.76e-260 802.0
HKD3_k127_8907332_1 PFAM GCN5-related N-acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 313.0
HKD3_k127_8907332_2 - - - - 0.000000000000000000000000000000000000000000000000000004831 194.0
HKD3_k127_8907332_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.000000000000000000000000000008145 118.0
HKD3_k127_8924698_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 8.447e-214 666.0
HKD3_k127_8932598_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 479.0
HKD3_k127_8932598_1 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 343.0
HKD3_k127_8932598_2 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000009383 195.0
HKD3_k127_8936113_0 homoserine dehydrogenase K00003 - 1.1.1.3 2.499e-194 608.0
HKD3_k127_8936113_1 amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 316.0
HKD3_k127_8936113_2 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000007655 149.0
HKD3_k127_8936113_3 PFAM Nitroreductase - - - 0.000000001966 58.0
HKD3_k127_8940295_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 369.0
HKD3_k127_8940295_1 Polyprenyl synthetase K02523 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 364.0
HKD3_k127_8954932_0 Baseplate J-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 485.0
HKD3_k127_8954932_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 437.0
HKD3_k127_8954932_2 Phage baseplate assembly protein W K06903 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 286.0
HKD3_k127_8954932_3 PAAR motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003406 271.0
HKD3_k127_8956266_0 phosphoglycerate mutase K15635 - 5.4.2.12 4.665e-204 635.0
HKD3_k127_8956266_1 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 544.0
HKD3_k127_8956266_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 342.0
HKD3_k127_8956266_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003566 261.0
HKD3_k127_8964507_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 453.0
HKD3_k127_8964507_1 PFAM major facilitator superfamily MFS_1 K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 426.0
HKD3_k127_8964507_2 COG0433 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009499 251.0
HKD3_k127_8981667_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.682e-216 669.0
HKD3_k127_8981667_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 327.0
HKD3_k127_8981667_2 Major Facilitator Superfamily - - - 0.0000000005511 60.0
HKD3_k127_8999727_0 WbqC-like protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 446.0
HKD3_k127_8999727_1 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 379.0
HKD3_k127_8999727_2 GlcNAc-PI de-N-acetylase - - - 0.0001959 47.0
HKD3_k127_9013950_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 414.0
HKD3_k127_9013950_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000006141 232.0
HKD3_k127_9013950_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000008131 144.0
HKD3_k127_9028000_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 414.0
HKD3_k127_9028000_1 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007369 328.0
HKD3_k127_902852_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 578.0
HKD3_k127_9038710_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 346.0
HKD3_k127_9041627_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003972 275.0
HKD3_k127_9041627_1 TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005387 246.0
HKD3_k127_9041627_2 - - - - 0.000000000000000000000000000000001169 130.0
HKD3_k127_9053756_0 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 500.0
HKD3_k127_9053756_1 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000001207 164.0
HKD3_k127_9058089_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 492.0
HKD3_k127_9058089_1 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 424.0
HKD3_k127_9058089_2 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 397.0
HKD3_k127_9058089_3 exosome subunit K07581 - - 0.00000000000000000001308 96.0
HKD3_k127_9059198_0 PFAM CBS domain - - - 9.38e-312 957.0
HKD3_k127_9059198_1 UPF0056 membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 359.0
HKD3_k127_9059198_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 298.0
HKD3_k127_9059198_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001174 264.0
HKD3_k127_9059198_4 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000001222 100.0
HKD3_k127_9062768_0 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000615 466.0
HKD3_k127_9062768_1 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 297.0
HKD3_k127_907313_0 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 1.373e-247 766.0
HKD3_k127_907313_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 595.0
HKD3_k127_907313_2 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 444.0
HKD3_k127_907313_3 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 368.0
HKD3_k127_907313_4 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 311.0
HKD3_k127_907313_5 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000007275 118.0
HKD3_k127_9075030_0 protein conserved in archaea - - - 2.308e-201 629.0
HKD3_k127_9077937_0 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 547.0
HKD3_k127_9077937_1 PFAM glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005595 335.0
HKD3_k127_9077937_2 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005488,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0046914,GO:0050897,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005205 311.0
HKD3_k127_9091844_0 RimK-like ATP-grasp domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 510.0
HKD3_k127_9091844_1 RimK-like ATPgrasp N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 441.0
HKD3_k127_9091844_2 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000000001026 109.0
HKD3_k127_9125137_0 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 363.0
HKD3_k127_9125137_1 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
HKD3_k127_9130987_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 3.275e-315 970.0
HKD3_k127_9134636_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000009717 223.0
HKD3_k127_9134636_1 protein conserved in archaea - - - 0.000000000000000000000000000000000000000000000002621 174.0
HKD3_k127_9134636_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000002626 142.0
HKD3_k127_9147139_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 427.0
HKD3_k127_9147139_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 428.0
HKD3_k127_9154137_0 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000001524 205.0
HKD3_k127_9154137_1 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000001069 149.0
HKD3_k127_9154137_2 - - - - 0.0000000000000000000000000000000000004119 146.0
HKD3_k127_9158616_0 amino acid K03294 - - 5.323e-215 672.0
HKD3_k127_9174159_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 2214.0
HKD3_k127_9174159_1 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 561.0
HKD3_k127_9174159_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 396.0
HKD3_k127_9174159_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007549 254.0
HKD3_k127_9176784_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 2.734e-226 702.0
HKD3_k127_9176784_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005199 396.0
HKD3_k127_9176784_2 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000000000000000000000000000000002827 191.0
HKD3_k127_9176784_3 - - - - 0.000000000000000000000000000000001655 130.0
HKD3_k127_9176784_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000001288 124.0
HKD3_k127_9198744_0 - - - - 2.855e-199 623.0
HKD3_k127_9198744_1 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 289.0
HKD3_k127_9200522_0 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 326.0
HKD3_k127_9200522_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004512 240.0
HKD3_k127_9200522_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000001482 183.0
HKD3_k127_9214413_0 Heparinase II/III-like protein - - - 0.0 1148.0
HKD3_k127_9214413_1 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000002426 235.0
HKD3_k127_9218834_0 CoA-binding domain protein K06929 - - 0.00000000000000000000000005211 111.0
HKD3_k127_9218834_1 Protein of unknown function (DUF1579) - - - 0.00000000000000000000000008536 115.0
HKD3_k127_9227095_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016427,GO:0016428,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 605.0
HKD3_k127_9227095_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001858 258.0
HKD3_k127_9227095_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000007407 162.0
HKD3_k127_9228897_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 580.0
HKD3_k127_9228897_1 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000000000000000000006241 175.0
HKD3_k127_9228897_2 - - - - 0.000000000000000000000000000000000005034 138.0
HKD3_k127_9228897_3 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.00000000000002142 74.0
HKD3_k127_9253250_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 279.0
HKD3_k127_9253250_1 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000009203 113.0
HKD3_k127_9270017_0 40-residue YVTN family beta-propeller - - - 0.0 1051.0
HKD3_k127_9270017_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 599.0
HKD3_k127_9274124_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 520.0
HKD3_k127_9274124_1 COG0433 Predicted ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 469.0
HKD3_k127_9274124_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 379.0
HKD3_k127_9274886_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 478.0
HKD3_k127_9274886_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 477.0
HKD3_k127_9274886_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008797 388.0
HKD3_k127_9274886_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000000000000000000000000000000000000000001837 204.0
HKD3_k127_9274886_4 binds to the 23S rRNA K02921 - - 0.0000000000000000000000000000000000000000000000000000002338 196.0
HKD3_k127_9274886_5 Transcription factor Pcc1 K09741 - - 0.00000000000000000000000000000000000000001438 155.0
HKD3_k127_9274886_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.0000000000000000000000004648 104.0
HKD3_k127_9280240_0 flavodoxin K00230 - 1.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 312.0
HKD3_k127_9280240_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002058 274.0
HKD3_k127_9280240_2 Flavodoxin K03839 - - 0.00000000000000000000000000000000000000000000000000000000000000005416 224.0
HKD3_k127_9280240_3 - - - - 0.0000000000000000000000000000000000000000000005847 170.0
HKD3_k127_9282053_0 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 3.57e-244 760.0
HKD3_k127_9282053_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 463.0
HKD3_k127_9282053_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000009138 237.0
HKD3_k127_9286365_0 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 374.0
HKD3_k127_9286365_1 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 304.0
HKD3_k127_9286365_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 282.0
HKD3_k127_9286365_3 Bacterial regulatory proteins, tetR family - - - 0.000000001665 59.0
HKD3_k127_9295916_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002299 231.0
HKD3_k127_9295916_1 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.00000000000000000000000000000000000000000000000000000000002657 206.0
HKD3_k127_9295916_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.0000000000000000000001186 97.0
HKD3_k127_929631_0 regulatory protein, arsR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 483.0
HKD3_k127_929631_1 - K09766 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 425.0
HKD3_k127_9319526_0 Pfam:DUF650 - - - 4.45e-273 841.0
HKD3_k127_9319526_1 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000685 207.0
HKD3_k127_9319526_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000000000000000000000000000007303 163.0
HKD3_k127_9319526_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000001746 108.0
HKD3_k127_9330120_0 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 554.0
HKD3_k127_9330120_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 321.0
HKD3_k127_9330120_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000003353 224.0
HKD3_k127_9332523_0 PFAM ABC transporter K00400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 338.0
HKD3_k127_9332523_1 Belongs to the UPF0288 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 316.0
HKD3_k127_9352331_0 SEC-C motif K06871 - - 6.263e-263 813.0
HKD3_k127_9352331_1 Sodium Bile acid symporter family K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 456.0
HKD3_k127_9352331_2 Sulfatase K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000002969 164.0
HKD3_k127_9352331_3 Domain of unknown function (DUF202) K00389 - - 0.0004861 48.0
HKD3_k127_9388613_0 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 432.0
HKD3_k127_9388613_1 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 317.0
HKD3_k127_9406524_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 399.0
HKD3_k127_9414131_0 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 519.0
HKD3_k127_9414131_1 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000006285 158.0
HKD3_k127_9416116_0 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 481.0
HKD3_k127_9431231_0 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 289.0
HKD3_k127_9431231_1 - - - - 0.0000000000000000000000000000000002241 132.0
HKD3_k127_9449397_0 4Fe-4S dicluster domain - - - 1.914e-230 713.0
HKD3_k127_9449397_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 425.0
HKD3_k127_9449397_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 418.0
HKD3_k127_9451331_0 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 408.0
HKD3_k127_9451331_1 - - - - 0.000003965 49.0
HKD3_k127_9451519_0 Met-10+ like-protein K07055 - 2.5.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 567.0
HKD3_k127_9451519_1 NMD protein affecting ribosome stability and mRNA decay K07562 - - 0.00000009838 55.0
HKD3_k127_9458035_0 cardiolipin biosynthetic process K02323,K02470,K03110,K03390,K07058 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,2.7.7.7,5.99.1.3 0.0 1660.0
HKD3_k127_9458035_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 580.0
HKD3_k127_9458945_0 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002314 265.0
HKD3_k127_9458945_1 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000001236 216.0
HKD3_k127_9464017_0 AAA-like domain K06915 - - 0.0 1005.0
HKD3_k127_9464017_1 - - - - 0.000000000000000000000000000000000000000000000000000000001122 200.0
HKD3_k127_9464017_2 B-block binding subunit of TFIIIC - - - 0.0000000000000006976 79.0
HKD3_k127_9475255_0 Type III secretion K03226 - - 0.00000000000000000000000000004954 117.0
HKD3_k127_9475255_1 Bacterial export proteins, family 3 K02420 - - 0.0000000000000000157 85.0
HKD3_k127_9475255_2 Bacterial export proteins, family 1 K03228 - - 0.00000000000001225 81.0
HKD3_k127_9537939_0 DegT/DnrJ/EryC1/StrS aminotransferase family K11717 - 2.8.1.7,4.4.1.16 1.656e-212 661.0
HKD3_k127_9537939_1 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000000000000000000006067 113.0
HKD3_k127_9537939_2 - - - - 0.000000000000005198 74.0
HKD3_k127_9540362_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 1.134e-214 668.0
HKD3_k127_9540362_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 362.0
HKD3_k127_9540362_2 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000005874 199.0
HKD3_k127_9541413_0 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000001881 138.0
HKD3_k127_9541831_0 COG1668 ABC-type Na efflux pump, permease component - - - 0.0 1000.0
HKD3_k127_9541831_1 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006822 530.0
HKD3_k127_9541831_2 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 426.0
HKD3_k127_9544729_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 362.0
HKD3_k127_9548603_0 TGS domain protein K06942 - - 4.469e-261 805.0
HKD3_k127_9548603_1 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004139 297.0
HKD3_k127_9548603_2 Peptidyl-prolyl cis-trans K01802,K03768,K03775 - 5.2.1.8 0.0000000000000000000000000000000001478 132.0
HKD3_k127_9564174_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.544e-283 871.0
HKD3_k127_9564174_1 PFAM thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003233 364.0
HKD3_k127_9567825_0 COGs COG1277 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 417.0
HKD3_k127_9567825_1 Domain of unknown function (DUF4162) K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009143 342.0
HKD3_k127_9590886_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 5.151e-223 692.0
HKD3_k127_9605590_0 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 529.0
HKD3_k127_9605590_1 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009184 236.0
HKD3_k127_9610181_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 6.736e-294 905.0
HKD3_k127_9621961_0 PFAM amino acid-binding ACT domain protein K06862 - - 4.765e-207 644.0
HKD3_k127_96305_0 - - - - 2.171e-240 744.0
HKD3_k127_96305_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005503 448.0
HKD3_k127_96305_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004664 253.0
HKD3_k127_965688_0 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 441.0
HKD3_k127_965688_1 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 315.0
HKD3_k127_993625_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0 1141.0
HKD3_k127_999533_0 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 523.0
HKD3_k127_999533_1 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000002725 238.0
HKD3_k127_999533_2 Rio2, N-terminal K07179 - 2.7.11.1 0.00000000000000000000000000000000000005557 143.0