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Overview

ID MAG01874
Name HKD3_bin.71
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class UBA6911
Order UBA6911
Family UBA6911
Genus JACADW01
Species JACADW01 sp017860075
Assembly information
Completeness (%) 72.27
Contamination (%) 1.12
GC content (%) 61.0
N50 (bp) 10,658
Genome size (bp) 3,849,055

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3126

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_1011453_0 Glycosyltransferase family 36 K18675 - 2.4.1.280 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 531.0
HKD3_k127_1011453_1 Major Facilitator Superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 488.0
HKD3_k127_1011453_2 Pentapeptide repeats (9 copies) - - - 0.0002033 46.0
HKD3_k127_1068268_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 548.0
HKD3_k127_1068268_1 PEP-CTERM system TPR-repeat lipoprotein - - - 0.00000000000004929 82.0
HKD3_k127_1163678_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.383e-195 624.0
HKD3_k127_1163678_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 353.0
HKD3_k127_1163678_2 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001509 265.0
HKD3_k127_1163678_3 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000007108 136.0
HKD3_k127_1163678_4 - - - - 0.000000000000004839 84.0
HKD3_k127_1189895_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 567.0
HKD3_k127_1189895_1 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002091 287.0
HKD3_k127_1211912_0 Uncharacterized protein family (UPF0051) K09014 - - 8.248e-266 824.0
HKD3_k127_1211912_1 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 593.0
HKD3_k127_1211912_10 transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000002944 151.0
HKD3_k127_1211912_2 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 471.0
HKD3_k127_1211912_3 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 415.0
HKD3_k127_1211912_4 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 392.0
HKD3_k127_1211912_5 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 354.0
HKD3_k127_1211912_6 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 328.0
HKD3_k127_1211912_7 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 286.0
HKD3_k127_1211912_8 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000000009873 216.0
HKD3_k127_1211912_9 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.0000000000000000000000000000000000005436 144.0
HKD3_k127_1213457_0 Prokaryotic cytochrome b561 - - - 8.371e-235 737.0
HKD3_k127_1213457_1 formate dehydrogenase - - - 5.781e-229 728.0
HKD3_k127_1214794_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 375.0
HKD3_k127_1214794_1 membrane-fusion protein - - - 0.000000000000000000000000000000000000004021 163.0
HKD3_k127_1214794_2 Smr domain - - - 0.00000000000000000000000000000000006061 142.0
HKD3_k127_1214794_3 HlyD family secretion protein - - - 0.000000000000001401 87.0
HKD3_k127_1214794_4 Belongs to the HesB IscA family - - - 0.0002839 44.0
HKD3_k127_1215386_0 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 308.0
HKD3_k127_1215386_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002694 281.0
HKD3_k127_1215386_2 Transposase K07491 - - 0.0000000000000000000000000000000000000000000000000000000000153 209.0
HKD3_k127_1215386_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000263 198.0
HKD3_k127_1215386_4 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000000000000000006189 183.0
HKD3_k127_1215386_5 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000001222 110.0
HKD3_k127_1223055_0 Glycosyl hydrolases family 2 K15855 - 3.2.1.165 8.814e-283 895.0
HKD3_k127_1223055_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 7.827e-245 776.0
HKD3_k127_1223055_10 ABC transporter K02003 - - 0.00000000000000000000000000000000000000002195 153.0
HKD3_k127_1223055_11 COG0720 6-pyruvoyl-tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000003413 148.0
HKD3_k127_1223055_12 Dehydrogenase - - - 0.00000000000000000000000000000000000006 153.0
HKD3_k127_1223055_13 Pentapeptide repeats (9 copies) K21919 - - 0.00000000000000000000000000000000002223 147.0
HKD3_k127_1223055_2 Glycosyltransferase 36 associated K18675 - 2.4.1.280 1.792e-214 670.0
HKD3_k127_1223055_3 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 497.0
HKD3_k127_1223055_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 502.0
HKD3_k127_1223055_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 485.0
HKD3_k127_1223055_6 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 441.0
HKD3_k127_1223055_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007885 277.0
HKD3_k127_1223055_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000006187 248.0
HKD3_k127_1223055_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000001401 203.0
HKD3_k127_1227054_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 354.0
HKD3_k127_1227054_1 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007704 359.0
HKD3_k127_1227054_2 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 310.0
HKD3_k127_1227054_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 288.0
HKD3_k127_1227054_4 Yip1 domain - - - 0.000000000000000001448 96.0
HKD3_k127_1227054_5 Phytol kinase K15892,K18678 - 2.7.1.182,2.7.1.216 0.000000002696 69.0
HKD3_k127_123522_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003202 299.0
HKD3_k127_123522_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000007571 245.0
HKD3_k127_123522_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000008206 214.0
HKD3_k127_123522_3 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000003897 118.0
HKD3_k127_1251359_0 Carbamoyl-phosphate synthetase large chain domain protein K01955 - 6.3.5.5 0.0 1392.0
HKD3_k127_1251359_1 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 334.0
HKD3_k127_1251437_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.614e-316 981.0
HKD3_k127_1251437_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000003905 229.0
HKD3_k127_1251437_2 With S4 and S5 plays an important role in translational accuracy K02950 - - 0.000000000000000000000000000001032 121.0
HKD3_k127_1251437_3 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000001698 81.0
HKD3_k127_1251579_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 545.0
HKD3_k127_1251579_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 467.0
HKD3_k127_1251579_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003961 264.0
HKD3_k127_1251579_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004022 263.0
HKD3_k127_1251579_4 V4R - - - 0.0000000000000000000000000000000000000000000000000000000000005578 237.0
HKD3_k127_1251579_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000001536 216.0
HKD3_k127_1251579_6 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000000000008013 195.0
HKD3_k127_1251579_7 PFAM Response regulator receiver domain K07713 - - 0.00000000000000000000000000000000000000000000000000037 190.0
HKD3_k127_1251579_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000001195 98.0
HKD3_k127_1252588_0 Glucose-6-phosphate dehydrogenase, NAD binding domain K00036 - 1.1.1.363,1.1.1.49 9.057e-224 701.0
HKD3_k127_1252588_1 Belongs to the GPI family K01810 - 5.3.1.9 4.003e-202 631.0
HKD3_k127_1252588_2 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 529.0
HKD3_k127_1259405_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 353.0
HKD3_k127_1259405_1 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000005943 248.0
HKD3_k127_1259405_2 glucokinase activity K00845 GO:0003674,GO:0003824,GO:0004340,GO:0004396,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019200,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046835,GO:0046939,GO:0051156,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.1.2 0.000000000000000000000000000000000000000000000000000317 199.0
HKD3_k127_1259405_3 regulatory protein, FmdB family - - - 0.0000000000000000000001949 100.0
HKD3_k127_1259405_4 - - - - 0.00000186 57.0
HKD3_k127_12739_0 enterobactin catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 610.0
HKD3_k127_12739_1 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 400.0
HKD3_k127_12739_2 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002858 278.0
HKD3_k127_12739_3 Transcription factor zinc-finger - - - 0.0000000000000000000000000000000000000000000000000008045 192.0
HKD3_k127_1273994_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 467.0
HKD3_k127_1273994_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 430.0
HKD3_k127_1273994_2 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 397.0
HKD3_k127_1273994_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 392.0
HKD3_k127_1273994_4 Peptidase M56 - - - 0.000000000000000000000000000000000000007628 164.0
HKD3_k127_1273994_5 Peptidase M56 - - - 0.000000000000000000000000000000000001463 157.0
HKD3_k127_1273994_6 Tetratricopeptide repeat - - - 0.000000000000000002184 91.0
HKD3_k127_1278053_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0 1295.0
HKD3_k127_1278053_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000003975 220.0
HKD3_k127_1278053_2 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000003939 173.0
HKD3_k127_1278053_3 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000007599 126.0
HKD3_k127_1286110_0 PFAM Glycoside hydrolase, clan GH-D K07407 - 3.2.1.22 1.134e-294 922.0
HKD3_k127_1286110_1 dipeptidyl-peptidase activity K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 412.0
HKD3_k127_1286110_2 ioli protein K06606 - 5.3.99.11 0.00000000000000000000000000000000000000000000000000000000000000000004014 237.0
HKD3_k127_1289115_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 387.0
HKD3_k127_1289115_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000002348 259.0
HKD3_k127_1289115_2 Yqey-like protein K09117 - - 0.0000000000000000000000000000000582 131.0
HKD3_k127_1289115_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - 0.00000006976 58.0
HKD3_k127_129372_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 469.0
HKD3_k127_129372_1 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 450.0
HKD3_k127_129372_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 347.0
HKD3_k127_1296030_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 581.0
HKD3_k127_1296030_1 Phytoene dehydrogenase K09835,K09845,K10027 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016119,GO:0016120,GO:0016491,GO:0016627,GO:0036094,GO:0042214,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046246,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.99.26,1.3.99.27,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 498.0
HKD3_k127_1296030_2 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 318.0
HKD3_k127_1296030_3 Conserved protein K01163 - - 0.00000000000000000000000000000000000000003003 164.0
HKD3_k127_1296030_4 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000003288 85.0
HKD3_k127_1296030_5 Amidohydrolase K07045 - - 0.0000000000000002105 90.0
HKD3_k127_1296030_6 TAT (twin-arginine translocation) pathway signal sequence - - - 0.000000005066 61.0
HKD3_k127_1296030_7 N-acetylglutamate synthase K00619 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 0.000006919 55.0
HKD3_k127_1299957_0 beta-galactosidase activity K01195 - 3.2.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 440.0
HKD3_k127_1299957_1 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 417.0
HKD3_k127_1308433_0 Melibiase K07407 - 3.2.1.22 1.288e-239 760.0
HKD3_k127_1308433_1 PIN domain K07064 - - 0.00003737 50.0
HKD3_k127_1308433_2 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0006584 46.0
HKD3_k127_1312014_0 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 404.0
HKD3_k127_1312014_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 383.0
HKD3_k127_1312014_3 Iron-storage protein K02217 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000000000004435 227.0
HKD3_k127_1312014_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000009457 152.0
HKD3_k127_1312014_5 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000006463 113.0
HKD3_k127_1317507_0 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 423.0
HKD3_k127_1317507_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 317.0
HKD3_k127_1323357_0 Cellulase N-terminal ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 455.0
HKD3_k127_1323357_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 428.0
HKD3_k127_1330453_0 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 447.0
HKD3_k127_1330453_1 Radical_SAM C-terminal domain K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 326.0
HKD3_k127_1330453_2 proteins, homologs of microcin C7 resistance protein MccF K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000004275 235.0
HKD3_k127_1330453_3 - - - - 0.0000000000000000105 83.0
HKD3_k127_1330904_0 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004902 406.0
HKD3_k127_1330904_1 Protein involved in outer membrane biogenesis K07289 - - 0.0000000000000000000000000000000000002542 146.0
HKD3_k127_1330904_2 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.00000000000000000000000000002205 119.0
HKD3_k127_1330904_3 PFAM peptidase M16 domain protein K07263 - - 0.0000000000000000004575 98.0
HKD3_k127_1332477_0 radical SAM domain protein K22318 - - 4.94e-226 715.0
HKD3_k127_1332477_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 416.0
HKD3_k127_1332477_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000005992 243.0
HKD3_k127_1332477_3 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000000000000000000000000000000000113 226.0
HKD3_k127_1332477_4 Belongs to the thymidylate synthase family. Archaeal- type ThyA subfamily K00560 - 2.1.1.45 0.00000000000000008274 92.0
HKD3_k127_1333935_0 PFAM Acetyl xylan esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 518.0
HKD3_k127_1333935_1 von Willebrand factor (vWF) type A domain K03404,K03405 - 6.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002703 430.0
HKD3_k127_1333935_2 amine dehydrogenase activity K00504,K12132 - 1.14.17.3,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009537 347.0
HKD3_k127_1333935_3 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000002844 74.0
HKD3_k127_1333935_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000007469 64.0
HKD3_k127_1351246_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 2.806e-311 976.0
HKD3_k127_1351246_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 2.828e-284 898.0
HKD3_k127_1351246_10 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002274 280.0
HKD3_k127_1351246_11 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.00000000000000000000000000000000000000000000000000000000000000000000000004574 260.0
HKD3_k127_1351246_12 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 253.0
HKD3_k127_1351246_13 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000000000000000000000000003233 203.0
HKD3_k127_1351246_14 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000004007 181.0
HKD3_k127_1351246_15 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000000000000000000000000000000000002911 175.0
HKD3_k127_1351246_16 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000000000005124 162.0
HKD3_k127_1351246_17 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000339 166.0
HKD3_k127_1351246_18 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000275 159.0
HKD3_k127_1351246_19 Soluble lytic murein transglycosylase-like protein - - - 0.0000000000000000000000000000000000002303 152.0
HKD3_k127_1351246_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 483.0
HKD3_k127_1351246_20 response regulator - - - 0.00000000000000000000000000000001753 137.0
HKD3_k127_1351246_21 Tetratricopeptide repeat - - - 0.00000000000000000000000009157 119.0
HKD3_k127_1351246_22 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000001418 119.0
HKD3_k127_1351246_23 - - - - 0.0000000000000000000000001618 110.0
HKD3_k127_1351246_24 - - - - 0.0000000000000000003017 100.0
HKD3_k127_1351246_25 Modulates RecA activity K03565 - - 0.0000006078 61.0
HKD3_k127_1351246_3 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 394.0
HKD3_k127_1351246_4 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 383.0
HKD3_k127_1351246_5 PFAM PfkB domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 365.0
HKD3_k127_1351246_6 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 366.0
HKD3_k127_1351246_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 328.0
HKD3_k127_1351246_8 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 305.0
HKD3_k127_1351246_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 298.0
HKD3_k127_1362584_0 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 526.0
HKD3_k127_1362584_1 Aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 518.0
HKD3_k127_1362584_10 Response regulator of the LytR AlgR family K02477 - - 0.00000000000000000000000000000000000000000000001314 181.0
HKD3_k127_1362584_11 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000001314 171.0
HKD3_k127_1362584_12 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000003343 175.0
HKD3_k127_1362584_13 Mur ligase middle domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000005517 162.0
HKD3_k127_1362584_14 von Willebrand factor, type A - - - 0.00000000000000000000000000000000332 143.0
HKD3_k127_1362584_15 Gram-negative-bacterium-type cell wall biogenesis - GO:0000270,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006807,GO:0008150,GO:0008152,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0030203,GO:0031224,GO:0042546,GO:0043164,GO:0043170,GO:0044085,GO:0044425,GO:0044464,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901564 - 0.000000000000000000000000003502 121.0
HKD3_k127_1362584_16 COG NOG25375 non supervised orthologous group - - - 0.000000000000009548 79.0
HKD3_k127_1362584_17 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.000007682 55.0
HKD3_k127_1362584_18 - - - - 0.000008955 55.0
HKD3_k127_1362584_2 Sodium:alanine symporter family K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 449.0
HKD3_k127_1362584_3 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 406.0
HKD3_k127_1362584_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002508 254.0
HKD3_k127_1362584_5 Psort location Cytoplasmic, score K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000009296 222.0
HKD3_k127_1362584_6 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000008837 214.0
HKD3_k127_1362584_7 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000009572 211.0
HKD3_k127_1362584_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000002772 217.0
HKD3_k127_1362584_9 phosphorelay sensor kinase activity K02478,K07704 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0007584,GO:0008150,GO:0008152,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016021,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0031224,GO:0031226,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0035556,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071496,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000007703 203.0
HKD3_k127_1373287_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 356.0
HKD3_k127_1373287_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000005181 213.0
HKD3_k127_1373287_2 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000002473 216.0
HKD3_k127_1373287_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000007824 193.0
HKD3_k127_1373287_4 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000001087 179.0
HKD3_k127_1373287_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000009125 169.0
HKD3_k127_1373287_6 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.00000000000000000000000000000009013 135.0
HKD3_k127_1375225_0 Belongs to the LDH2 MDH2 oxidoreductase family K08092 - 1.1.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 421.0
HKD3_k127_1375225_1 cell redox homeostasis K00384,K12057,K12267,K21636 - 1.1.98.6,1.8.1.9,1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000006006 205.0
HKD3_k127_1375225_2 iron-sulfur cluster assembly K07400 - - 0.00000000000000000000000000000000000000000186 167.0
HKD3_k127_1375225_3 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000813 161.0
HKD3_k127_1375386_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009989 381.0
HKD3_k127_1375386_1 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000002904 110.0
HKD3_k127_1381540_0 H( )-stimulated, divalent metal cation uptake system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 517.0
HKD3_k127_1381540_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000002535 218.0
HKD3_k127_1381540_2 Squalene/phytoene synthase K00801,K02291,K10208 GO:0003674,GO:0003824,GO:0004337,GO:0004659,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016108,GO:0016109,GO:0016114,GO:0016116,GO:0016117,GO:0016740,GO:0016765,GO:0016767,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046148,GO:0071704,GO:1901576 2.5.1.21,2.5.1.32,2.5.1.96,2.5.1.99 0.00000000000000000000002916 104.0
HKD3_k127_1392800_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 541.0
HKD3_k127_1392800_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 426.0
HKD3_k127_1392800_2 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001385 271.0
HKD3_k127_1392800_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000001675 235.0
HKD3_k127_1392800_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.0000000000000000000000000000000000000000000000000008921 196.0
HKD3_k127_1392800_5 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000003394 178.0
HKD3_k127_1392800_6 Kef-type potassium proton antiporter, CPA2 family K03455 - - 0.000000000000000000000000000000005045 135.0
HKD3_k127_1392800_7 acetamidase formamidase - - - 0.000000000009348 72.0
HKD3_k127_1392800_8 - - - - 0.00000001685 65.0
HKD3_k127_1392800_9 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K00256 - 1.3.99.16 0.000001691 53.0
HKD3_k127_1412134_0 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000239 252.0
HKD3_k127_1412134_1 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001166 247.0
HKD3_k127_1412134_2 Adenylate cyclase - - - 0.000000000000000000000000000991 118.0
HKD3_k127_1412134_3 Ami_3 K01448 - 3.5.1.28 0.00004235 54.0
HKD3_k127_1412935_0 TonB-dependent receptor - - - 7.892e-240 769.0
HKD3_k127_1412935_1 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 319.0
HKD3_k127_1412935_2 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008076 272.0
HKD3_k127_1412935_3 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000004863 155.0
HKD3_k127_1412935_4 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000007331 141.0
HKD3_k127_1412935_5 Spermidine putrescine ABC transporter ATPase K02010 - 3.6.3.30 0.000000000000000000000000001106 121.0
HKD3_k127_1423669_0 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000175 246.0
HKD3_k127_1432615_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 7.242e-208 676.0
HKD3_k127_1432615_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 567.0
HKD3_k127_1432615_2 PFAM Major facilitator superfamily K02429 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 407.0
HKD3_k127_1432615_3 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 324.0
HKD3_k127_1432615_4 Cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000001699 105.0
HKD3_k127_143960_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 565.0
HKD3_k127_143960_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 411.0
HKD3_k127_143960_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 374.0
HKD3_k127_143960_3 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008769 289.0
HKD3_k127_1450147_0 Insulinase (Peptidase family M16) K07263 - - 1.949e-306 968.0
HKD3_k127_1450147_1 coproporphyrinogen oxidase activity K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 462.0
HKD3_k127_1450147_2 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 403.0
HKD3_k127_1450147_4 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000526 181.0
HKD3_k127_1450147_5 hydrolase, family 65, central catalytic K15923 - 3.2.1.51 0.000000000000000000000000000000002492 139.0
HKD3_k127_1462028_0 Sortilin, neurotensin receptor 3, - - - 0.0 1182.0
HKD3_k127_1462028_1 cephalosporin-C deacetylase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 614.0
HKD3_k127_1462028_10 Domain of unknown function (DUF4416) - - - 0.0000000000000009978 77.0
HKD3_k127_1462028_2 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 513.0
HKD3_k127_1462028_3 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 496.0
HKD3_k127_1462028_4 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 448.0
HKD3_k127_1462028_5 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 357.0
HKD3_k127_1462028_6 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002801 270.0
HKD3_k127_1462028_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006043 270.0
HKD3_k127_1462028_9 - - - - 0.000000000000000000000000000007881 126.0
HKD3_k127_1463163_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 607.0
HKD3_k127_1463163_1 TIGRFAM ATPase, FliI YscN family K02412,K03224 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 519.0
HKD3_k127_1463163_10 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.0000000000000000000000000004002 122.0
HKD3_k127_1463163_11 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000002181 95.0
HKD3_k127_1463163_12 Flagellar assembly protein FliH K02411 - - 0.0000000000000000007934 96.0
HKD3_k127_1463163_13 Flagellar hook-basal body complex protein FliE K02408 - - 0.000000000000000001947 88.0
HKD3_k127_1463163_14 flagellar export protein FliJ K02413 - - 0.0006758 48.0
HKD3_k127_1463163_2 belongs to the lyase 1 family. Argininosuccinate lyase subfamily K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007823 478.0
HKD3_k127_1463163_3 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 442.0
HKD3_k127_1463163_4 PFAM sigma-54 factor interaction domain-containing protein K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 432.0
HKD3_k127_1463163_5 flagellar motor switch protein FliG K02410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 366.0
HKD3_k127_1463163_6 The M ring may be actively involved in energy transduction K02409 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002588 296.0
HKD3_k127_1463163_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000001278 236.0
HKD3_k127_1463163_8 phosphorelay sensor kinase activity K07708,K07710,K10942 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001551 241.0
HKD3_k127_1463163_9 flagellar basal-body rod protein FlgC K02388 - - 0.00000000000000000000000000000000000001253 151.0
HKD3_k127_146590_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.41e-321 1003.0
HKD3_k127_146590_1 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 3.784e-299 948.0
HKD3_k127_146590_10 Type II transport protein GspH K08084 - - 0.00003055 53.0
HKD3_k127_146590_2 Zn_pept - - - 4.76e-234 750.0
HKD3_k127_146590_3 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 496.0
HKD3_k127_146590_4 Major Facilitator Superfamily K08191 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 448.0
HKD3_k127_146590_5 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 430.0
HKD3_k127_146590_6 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 319.0
HKD3_k127_146590_7 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004382 270.0
HKD3_k127_146590_8 iron ion homeostasis K03709,K04758 - - 0.000000000000000000000000000000000000000000001014 173.0
HKD3_k127_146590_9 - - - - 0.0000001108 54.0
HKD3_k127_1471675_0 Sulfatase - - - 0.0000000000000000000000000000000000000000000001533 171.0
HKD3_k127_1471675_1 Protein of unknown function (DUF2490) - - - 0.0000000000000000000000000000000000001364 150.0
HKD3_k127_1471675_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000003141 133.0
HKD3_k127_1471675_3 serine threonine protein kinase - - - 0.00004913 47.0
HKD3_k127_1472554_0 ammonia-lyase activity K01745 - 4.3.1.3 3.959e-260 809.0
HKD3_k127_1472554_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 509.0
HKD3_k127_1472554_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 418.0
HKD3_k127_1472554_3 Putative neutral zinc metallopeptidase K07054 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 387.0
HKD3_k127_1472554_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 308.0
HKD3_k127_1472554_5 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000006938 136.0
HKD3_k127_1472554_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000004454 94.0
HKD3_k127_1472554_7 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000003955 68.0
HKD3_k127_1472554_8 - - - - 0.00000007665 58.0
HKD3_k127_1481315_0 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000005889 240.0
HKD3_k127_1481315_1 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000001003 237.0
HKD3_k127_1481625_0 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000006574 190.0
HKD3_k127_1481625_1 Fimbrial assembly protein (PilN) K02461 - - 0.000000000000000000000000007719 126.0
HKD3_k127_1481625_2 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.0000000004586 69.0
HKD3_k127_1484766_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 514.0
HKD3_k127_1484766_1 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.0000000000000000000000000000000000000000003556 160.0
HKD3_k127_1492647_0 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008637 511.0
HKD3_k127_1492647_1 Domain of unknown function (DUF4091) - - - 0.000000000000000000000000000000000000000000000000000000001139 222.0
HKD3_k127_1492647_2 Domain of unknown function (DUF5107) - - - 0.0000000000000000000000000000000000000000006427 173.0
HKD3_k127_1502511_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 531.0
HKD3_k127_1502511_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 353.0
HKD3_k127_1502511_10 - - - - 0.0009052 47.0
HKD3_k127_1502511_2 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 309.0
HKD3_k127_1502511_3 cobalamin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 268.0
HKD3_k127_1502511_4 Glycosyl hydrolase family 9 - - - 0.00000000000000000000000000000000000000000000000000000000000000003402 245.0
HKD3_k127_1502511_5 - - - - 0.000000000000000000000000000000000000709 151.0
HKD3_k127_1502511_6 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000004857 146.0
HKD3_k127_1502511_7 alpha/beta hydrolase fold K01253 - 3.3.2.9 0.00000000000000000000000000000001079 140.0
HKD3_k127_1502511_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.00000000000000000000000000000001668 128.0
HKD3_k127_1502511_9 - - - - 0.0000000000000000001957 97.0
HKD3_k127_1541052_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 540.0
HKD3_k127_1541052_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 305.0
HKD3_k127_1541052_2 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001432 261.0
HKD3_k127_1541052_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000006559 244.0
HKD3_k127_1541052_4 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000002983 124.0
HKD3_k127_1541052_5 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000009378 70.0
HKD3_k127_1548871_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.172e-313 972.0
HKD3_k127_1548871_1 TonB dependent receptor K02014,K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006338 300.0
HKD3_k127_1548871_2 Heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000000000000002871 194.0
HKD3_k127_1548871_3 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000004606 178.0
HKD3_k127_1548871_4 PFAM ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000005962 171.0
HKD3_k127_1548871_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.000000000000000000000000000000009914 135.0
HKD3_k127_1557754_0 TonB-dependent receptor - - - 6.271e-239 761.0
HKD3_k127_1557754_1 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.00000000000000000000000000000000006108 141.0
HKD3_k127_1557754_2 FecR protein - - - 0.0000000000000000000000000001625 124.0
HKD3_k127_1557754_3 Membrane - - - 0.000000000000000000000006132 108.0
HKD3_k127_1557754_4 EthD domain - - - 0.0000000000000000000007188 99.0
HKD3_k127_1557754_5 Fic/DOC family - - - 0.0000001064 58.0
HKD3_k127_1565522_0 Carboxypeptidase regulatory-like domain - - - 0.0 1103.0
HKD3_k127_1565522_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.35e-221 698.0
HKD3_k127_1565522_2 FAD dependent oxidoreductase - - - 2.076e-194 647.0
HKD3_k127_1565522_3 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 381.0
HKD3_k127_1565522_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 373.0
HKD3_k127_1565522_5 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006531 292.0
HKD3_k127_1565522_6 Glycosyl hydrolase family 36 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000112 258.0
HKD3_k127_1565522_7 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000001929 203.0
HKD3_k127_1565522_8 beta-galactosidase - - - 0.0007429 53.0
HKD3_k127_1571191_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.946e-240 760.0
HKD3_k127_1571191_1 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 501.0
HKD3_k127_1571191_2 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 350.0
HKD3_k127_1571191_3 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000004865 125.0
HKD3_k127_1586094_0 ASPIC and UnbV - - - 2.049e-216 717.0
HKD3_k127_1586094_1 NeuB family K03856 - 2.5.1.54 0.0000000001804 61.0
HKD3_k127_1626567_0 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000004482 174.0
HKD3_k127_1626567_1 40-residue YVTN family beta-propeller repeat - - - 0.000000007071 69.0
HKD3_k127_1626567_2 Belongs to the UPF0232 family - - - 0.000004554 52.0
HKD3_k127_1626567_3 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.00001306 56.0
HKD3_k127_1648942_0 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence - - - 2.848e-225 712.0
HKD3_k127_1648942_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 464.0
HKD3_k127_1648942_2 peptidyl-tyrosine sulfation - - - 0.00000000009207 74.0
HKD3_k127_1648942_3 methyltransferase activity K21310 - 2.1.1.334 0.000002145 55.0
HKD3_k127_1649480_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000007758 183.0
HKD3_k127_1649480_1 Beta-lactamase - - - 0.00000001203 56.0
HKD3_k127_1649480_2 Protein of unknown function (DUF3494) - - - 0.0003141 53.0
HKD3_k127_1650970_0 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004232 285.0
HKD3_k127_1650970_1 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000204 240.0
HKD3_k127_1655080_0 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 409.0
HKD3_k127_1655080_1 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 326.0
HKD3_k127_1655080_2 Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 302.0
HKD3_k127_1655080_3 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 305.0
HKD3_k127_1655080_4 COG2706 3-carboxymuconate cyclase K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000543 207.0
HKD3_k127_1657707_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1077.0
HKD3_k127_1657707_1 Peptidase family M23 - - - 0.00000000000000000000000000000000000003073 152.0
HKD3_k127_1657707_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000002002 124.0
HKD3_k127_1682012_0 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 452.0
HKD3_k127_1682012_1 Glycosyltransferase like family 2 - - - 0.00000000000006072 76.0
HKD3_k127_16891_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 552.0
HKD3_k127_16891_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001386 261.0
HKD3_k127_16891_2 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000001126 117.0
HKD3_k127_1692919_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 411.0
HKD3_k127_1692919_1 Integrase core domain - - - 0.000000000007843 67.0
HKD3_k127_1704298_0 Two component transcriptional regulator, winged helix family K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 337.0
HKD3_k127_1704298_1 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000354 281.0
HKD3_k127_1718895_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1712.0
HKD3_k127_1718895_1 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 443.0
HKD3_k127_1718895_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000000005295 130.0
HKD3_k127_1776130_0 Domain of unknown function (DUF5107) - - - 2.237e-241 780.0
HKD3_k127_1776130_1 alpha-mannosidase activity - - - 5.796e-234 753.0
HKD3_k127_1776130_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 338.0
HKD3_k127_1776130_3 signal transduction protein containing EAL and modified HD-GYP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 346.0
HKD3_k127_1776130_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 290.0
HKD3_k127_1776130_5 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001178 285.0
HKD3_k127_1776130_6 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000002955 112.0
HKD3_k127_1776130_7 antisigma factor binding K04749 - - 0.000000000000000000000309 100.0
HKD3_k127_1776130_8 ABC-type transport system involved in resistance to organic solvents, periplasmic component K02067 - - 0.00004984 51.0
HKD3_k127_1793670_0 nuclear chromosome segregation - - - 0.000007524 58.0
HKD3_k127_1866291_0 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 495.0
HKD3_k127_1866291_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 306.0
HKD3_k127_1866291_2 - - - - 0.00000000000000000000000000000000000000000005175 169.0
HKD3_k127_1954676_0 Cys/Met metabolism PLP-dependent enzyme K01042 - 2.9.1.1 8.893e-231 727.0
HKD3_k127_1954676_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 470.0
HKD3_k127_1954676_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 324.0
HKD3_k127_1954676_3 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006606 256.0
HKD3_k127_1954676_4 - - - - 0.0000000000000000002145 94.0
HKD3_k127_1955377_0 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 404.0
HKD3_k127_1955377_1 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009213 329.0
HKD3_k127_1955377_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000032 246.0
HKD3_k127_1955377_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000003482 214.0
HKD3_k127_1955377_4 NosL K19342 - - 0.000000000001788 74.0
HKD3_k127_2003878_0 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 388.0
HKD3_k127_2003878_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000007615 168.0
HKD3_k127_2003878_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000001619 118.0
HKD3_k127_2003878_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000004159 68.0
HKD3_k127_201309_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 2.742e-292 909.0
HKD3_k127_201309_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 5.374e-205 659.0
HKD3_k127_201309_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000001517 134.0
HKD3_k127_201309_11 - - - - 0.0000007867 57.0
HKD3_k127_201309_2 threonine synthase activity K01733 - 4.2.3.1 1.419e-197 625.0
HKD3_k127_201309_3 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 520.0
HKD3_k127_201309_4 SEC-C motif K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 484.0
HKD3_k127_201309_5 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 317.0
HKD3_k127_201309_6 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 310.0
HKD3_k127_201309_7 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008464 281.0
HKD3_k127_201309_8 hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000002318 193.0
HKD3_k127_201309_9 SdpI/YhfL protein family - - - 0.0000000000000000000000000000000000000000000000008686 186.0
HKD3_k127_2018879_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 1.989e-211 664.0
HKD3_k127_2018879_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000003018 209.0
HKD3_k127_2018879_2 radical SAM K21312 - 1.17.98.2 0.000002806 58.0
HKD3_k127_2044166_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 4.726e-215 677.0
HKD3_k127_2044166_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006457,GO:0006605,GO:0006810,GO:0006886,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015627,GO:0015628,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0034613,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042802,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061077,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:0098776,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 344.0
HKD3_k127_2044166_2 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000008305 128.0
HKD3_k127_2044166_3 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000007581 59.0
HKD3_k127_2044166_4 integral membrane protein - - - 0.00001948 55.0
HKD3_k127_2120116_0 family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 374.0
HKD3_k127_2120116_1 cAMP biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001318 281.0
HKD3_k127_2120116_2 Met-10+ like-protein - - - 0.0000000000000000000000000000000000000000000001018 174.0
HKD3_k127_2131850_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 320.0
HKD3_k127_2131850_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000003927 211.0
HKD3_k127_2131850_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision - - - 0.000000000000004216 89.0
HKD3_k127_2149283_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003756 618.0
HKD3_k127_2149283_1 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 350.0
HKD3_k127_2149283_10 peptidyl-tyrosine sulfation - - - 0.0000000000005043 81.0
HKD3_k127_2149283_11 - - - - 0.000000000003619 73.0
HKD3_k127_2149283_12 metal cluster binding - - - 0.00000000005485 70.0
HKD3_k127_2149283_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001481 270.0
HKD3_k127_2149283_3 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003739 238.0
HKD3_k127_2149283_4 PFAM PQQ enzyme repeat - - - 0.00000000000000000000000000000000000000000000000000000000001604 223.0
HKD3_k127_2149283_5 Acetyltransferase (GNAT) domain K01139,K03790 - 2.3.1.128,2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000001582 194.0
HKD3_k127_2149283_6 ACT domain K09964 - - 0.00000000000000000000000000000000000000000009234 163.0
HKD3_k127_2149283_7 - K19051 GO:0003674,GO:0003824,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006082,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008201,GO:0009056,GO:0009057,GO:0009987,GO:0016829,GO:0016835,GO:0016837,GO:0030202,GO:0030203,GO:0030211,GO:0042597,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044248,GO:0044273,GO:0044281,GO:0044464,GO:0047488,GO:0071704,GO:0097367,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1901681,GO:1903510 4.2.2.7,4.2.2.8 0.000000000000000000000000000000005566 147.0
HKD3_k127_2149283_8 - - - - 0.000000000000000009252 94.0
HKD3_k127_2149283_9 Fibronectin type 3 domain - - - 0.0000000000002581 84.0
HKD3_k127_2290637_0 Arylsulfatase a K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 499.0
HKD3_k127_2290637_1 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 318.0
HKD3_k127_2290637_2 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.000000000000000000000000000000000000000000000000004922 191.0
HKD3_k127_2290637_3 - - - - 0.00007279 50.0
HKD3_k127_2290637_4 - - - - 0.0005123 43.0
HKD3_k127_2323750_0 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 483.0
HKD3_k127_2323750_1 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 381.0
HKD3_k127_2323750_2 Bacterial sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 342.0
HKD3_k127_234259_0 Predicted membrane protein (DUF2339) - - - 5.013e-274 885.0
HKD3_k127_234259_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 481.0
HKD3_k127_234259_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 338.0
HKD3_k127_234259_3 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004019 258.0
HKD3_k127_234259_4 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000009066 204.0
HKD3_k127_234259_5 - - - - 0.0000000000000000000000000000000000000001015 160.0
HKD3_k127_234259_6 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000008282 57.0
HKD3_k127_236124_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 1.353e-215 678.0
HKD3_k127_236124_1 Flavin containing amine oxidoreductase K09835,K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 488.0
HKD3_k127_236124_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 317.0
HKD3_k127_236124_3 dUTPase K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000001711 224.0
HKD3_k127_2420370_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008676 408.0
HKD3_k127_2420370_1 PEP-utilising enzyme, N-terminal K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007596 412.0
HKD3_k127_2420370_10 PTS HPr component phosphorylation site - - - 0.000000000000000003269 88.0
HKD3_k127_2420370_2 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 396.0
HKD3_k127_2420370_3 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 312.0
HKD3_k127_2420370_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 314.0
HKD3_k127_2420370_5 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 297.0
HKD3_k127_2420370_6 cell septum assembly - - - 0.0000000000000000000000000000000000000000000000000000001039 219.0
HKD3_k127_2420370_7 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.0000000000000000000000000000000008696 134.0
HKD3_k127_2420370_8 lipopolysaccharide transport K09774 - - 0.0000000000000000000000000000002412 143.0
HKD3_k127_2420370_9 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000003708 103.0
HKD3_k127_2421630_0 phosphorelay signal transduction system K07712,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004457 499.0
HKD3_k127_2421630_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 308.0
HKD3_k127_2421630_2 CHASE - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 308.0
HKD3_k127_2421630_3 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008236 271.0
HKD3_k127_2421630_4 membrane protein of uknown function UCP014873 - - - 0.0000000000000000000000000000000488 132.0
HKD3_k127_2421630_5 Belongs to the peptidase S1C family - - - 0.0000000000000000000000000291 113.0
HKD3_k127_2421630_6 Histidine kinase - - - 0.000000000000000000000002242 110.0
HKD3_k127_2423184_0 Urocanase Rossmann-like domain K01712 - 4.2.1.49 1.961e-273 851.0
HKD3_k127_2423184_1 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 531.0
HKD3_k127_2423184_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 442.0
HKD3_k127_2423184_3 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006482 288.0
HKD3_k127_2423184_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000002636 170.0
HKD3_k127_2423184_5 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source K10778 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 2.1.1.63 0.00000000002077 66.0
HKD3_k127_2431848_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 5.831e-221 700.0
HKD3_k127_2431848_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 480.0
HKD3_k127_2431848_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 359.0
HKD3_k127_2431848_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000002106 188.0
HKD3_k127_2431848_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000003565 152.0
HKD3_k127_2431848_5 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.00000000000000000000000000000000002101 136.0
HKD3_k127_2431848_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000001692 66.0
HKD3_k127_2431848_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000008566 63.0
HKD3_k127_2431848_8 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000009758 59.0
HKD3_k127_2431848_9 - - - - 0.0002688 47.0
HKD3_k127_2450070_0 Putative citrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 328.0
HKD3_k127_2450070_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 310.0
HKD3_k127_2459964_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000005063 81.0
HKD3_k127_2459964_1 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000000000001081 85.0
HKD3_k127_246412_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000001067 144.0
HKD3_k127_2470170_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.797e-257 816.0
HKD3_k127_2470170_1 elongation factor G domain IV K02355 - - 2.48e-239 759.0
HKD3_k127_2470170_10 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000008503 187.0
HKD3_k127_2470170_11 PFAM von Willebrand factor type A - - - 0.000000000000000000000000000000000002381 145.0
HKD3_k127_2470170_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 447.0
HKD3_k127_2470170_3 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 310.0
HKD3_k127_2470170_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000001222 273.0
HKD3_k127_2470170_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001251 267.0
HKD3_k127_2470170_6 HNH nucleases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005743 243.0
HKD3_k127_2470170_7 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001937 249.0
HKD3_k127_2470170_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007301 242.0
HKD3_k127_2470170_9 dCMP deaminase activity K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000003865 205.0
HKD3_k127_2472735_0 Cyclopropane fatty acid synthase and related K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 399.0
HKD3_k127_2472735_1 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000002177 165.0
HKD3_k127_2502546_0 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 472.0
HKD3_k127_2502546_1 oxidation-reduction process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 396.0
HKD3_k127_2502546_2 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 329.0
HKD3_k127_2502546_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 302.0
HKD3_k127_25411_0 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 529.0
HKD3_k127_25411_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004198 435.0
HKD3_k127_25411_10 Domain of unknown function (DUF4136) - - - 0.000000000000002285 83.0
HKD3_k127_25411_2 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 342.0
HKD3_k127_25411_3 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 330.0
HKD3_k127_25411_4 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 307.0
HKD3_k127_25411_5 Ferritin Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000009768 263.0
HKD3_k127_25411_6 selenocysteine lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004037 267.0
HKD3_k127_25411_8 HDOD domain - - - 0.000000000000000000000007289 112.0
HKD3_k127_25411_9 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000009034 99.0
HKD3_k127_2549980_0 Tricorn protease PDZ domain K08676 - - 0.0 1328.0
HKD3_k127_2549980_1 lysine biosynthetic process via aminoadipic acid - - - 2.554e-231 743.0
HKD3_k127_2549980_2 dipeptidyl-peptidase activity K06978 - - 5.275e-212 683.0
HKD3_k127_2549980_3 Acetamidase/Formamidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 337.0
HKD3_k127_2549980_4 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005015 264.0
HKD3_k127_2549980_5 F5 8 type C domain - - - 0.00000000000000000000000000000000000000000008602 181.0
HKD3_k127_2549980_6 amidohydrolase - - - 0.000000000000000000000000000000000009808 150.0
HKD3_k127_2549980_7 Integrase - - - 0.000000000000000000000000002949 114.0
HKD3_k127_2549980_8 Beta-lactamase - - - 0.000000000000000000001662 111.0
HKD3_k127_2552976_0 radical SAM domain protein K22318 - - 6.787e-197 629.0
HKD3_k127_2552976_1 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 507.0
HKD3_k127_2552976_2 PFAM Neutral alkaline nonlysosomal ceramidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 398.0
HKD3_k127_2552976_3 Belongs to the arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 318.0
HKD3_k127_2552976_7 PFAM aldo keto reductase - - - 0.000000000000000000000000002168 114.0
HKD3_k127_2552976_8 4-phosphoerythronate dehydrogenase activity - - - 0.0001242 44.0
HKD3_k127_2569285_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 559.0
HKD3_k127_2569285_1 transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 398.0
HKD3_k127_2585387_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 407.0
HKD3_k127_2585387_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000000000000000000000003191 242.0
HKD3_k127_2585387_2 - - - - 0.000000000000000000000000000000000000000000000000000000008026 206.0
HKD3_k127_2585387_3 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K01768,K07315 - 3.1.3.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000001646 203.0
HKD3_k127_2585387_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000006317 176.0
HKD3_k127_2585387_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000001506 163.0
HKD3_k127_2585387_6 - - - - 0.0000000000000007035 78.0
HKD3_k127_2588859_0 Mandelate Racemase Muconate Lactonizing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 599.0
HKD3_k127_2588859_1 Dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002063 479.0
HKD3_k127_2588859_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000003876 218.0
HKD3_k127_2610422_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1416.0
HKD3_k127_2610422_1 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 1.384e-198 645.0
HKD3_k127_2610422_10 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000001937 181.0
HKD3_k127_2610422_11 HD domain K07814 - - 0.00000000000000000000000000001169 126.0
HKD3_k127_2610422_12 Roadblock/LC7 domain - - - 0.000000000000000000000001214 111.0
HKD3_k127_2610422_13 Tetratricopeptide repeat - - - 0.0000000000001802 80.0
HKD3_k127_2610422_14 von Willebrand factor type A domain K07114 - - 0.000000001877 69.0
HKD3_k127_2610422_15 - - - - 0.000000005066 61.0
HKD3_k127_2610422_2 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 500.0
HKD3_k127_2610422_3 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 479.0
HKD3_k127_2610422_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528,K16203 GO:0000270,GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030203,GO:0030260,GO:0033692,GO:0034637,GO:0034645,GO:0035635,GO:0040007,GO:0042546,GO:0043167,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009863 426.0
HKD3_k127_2610422_5 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 332.0
HKD3_k127_2610422_6 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007603 354.0
HKD3_k127_2610422_7 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 298.0
HKD3_k127_2610422_8 - K06862 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 253.0
HKD3_k127_2610422_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000001965 221.0
HKD3_k127_2624379_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1080.0
HKD3_k127_2624379_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 456.0
HKD3_k127_2624379_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 422.0
HKD3_k127_2624379_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 317.0
HKD3_k127_2624379_4 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 259.0
HKD3_k127_2624379_5 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000004084 232.0
HKD3_k127_2624379_6 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000003078 175.0
HKD3_k127_2624379_7 Preprotein translocase subunit K03210 - - 0.00000000000000000009346 93.0
HKD3_k127_2624706_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002179 289.0
HKD3_k127_2624706_1 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000001086 205.0
HKD3_k127_2624706_2 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K13940 - 2.7.6.3,4.1.2.25 0.0000000000000000000000000000000000000156 150.0
HKD3_k127_2624706_3 PFAM Organic solvent tolerance protein K04744 - - 0.000000000005079 68.0
HKD3_k127_2624706_4 SpoIIAA-like - - - 0.0000001443 61.0
HKD3_k127_2632511_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1184.0
HKD3_k127_2632511_1 COGs COG0471 Di- and tricarboxylate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 351.0
HKD3_k127_2632511_2 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000001647 186.0
HKD3_k127_2644469_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 305.0
HKD3_k127_2644469_1 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000001325 168.0
HKD3_k127_2644469_2 - - - - 0.000000000000000001707 87.0
HKD3_k127_2644469_3 membrane - - - 0.0007651 51.0
HKD3_k127_2646939_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 538.0
HKD3_k127_2646939_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 298.0
HKD3_k127_265163_0 Protein of unknown function (DUF1009) K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002025 277.0
HKD3_k127_265163_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0008780,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000004274 269.0
HKD3_k127_265163_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001598 266.0
HKD3_k127_265163_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000003782 173.0
HKD3_k127_265163_4 Outer membrane protein (OmpH-like) K06142 - - 0.00000002866 59.0
HKD3_k127_2664312_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 7.903e-273 859.0
HKD3_k127_2664312_1 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 419.0
HKD3_k127_2664312_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000009068 184.0
HKD3_k127_2683247_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1627.0
HKD3_k127_2683247_1 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 365.0
HKD3_k127_2683247_10 oxidoreductase FAD NAD(P)-binding K00523,K00528 - 1.17.1.1,1.18.1.2,1.19.1.1 0.0000000000000000000000000001831 127.0
HKD3_k127_2683247_11 Protein of unknown function (DUF971) - - - 0.0000000000000000000000004278 107.0
HKD3_k127_2683247_12 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000001805 66.0
HKD3_k127_2683247_13 - - - - 0.0006682 51.0
HKD3_k127_2683247_2 SIS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005305 313.0
HKD3_k127_2683247_3 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 302.0
HKD3_k127_2683247_4 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 293.0
HKD3_k127_2683247_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001535 273.0
HKD3_k127_2683247_6 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005588 274.0
HKD3_k127_2683247_7 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006486 264.0
HKD3_k127_2683247_8 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000002599 225.0
HKD3_k127_2683247_9 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000002895 208.0
HKD3_k127_2689072_0 PFAM glycoside hydrolase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 406.0
HKD3_k127_2689072_1 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 322.0
HKD3_k127_2689072_2 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001063 287.0
HKD3_k127_2702732_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000002324 224.0
HKD3_k127_2702732_1 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000002506 205.0
HKD3_k127_2702732_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000006454 164.0
HKD3_k127_2702732_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000002992 152.0
HKD3_k127_2702732_4 multi-organism process K03195 - - 0.000000000000000000000005785 110.0
HKD3_k127_2702732_5 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000004464 91.0
HKD3_k127_2702732_6 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.000000007053 68.0
HKD3_k127_2702732_7 CAAX protease self-immunity K07052 - - 0.00000002507 64.0
HKD3_k127_2702732_8 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.21.53 0.00008226 45.0
HKD3_k127_2705492_0 Protein of unknown function (DUF2961) - - - 0.00000000000000000000000000000000000000000000000000001818 203.0
HKD3_k127_270825_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000001229 202.0
HKD3_k127_270825_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0008562 43.0
HKD3_k127_2710756_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 591.0
HKD3_k127_2710756_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 336.0
HKD3_k127_2710756_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 327.0
HKD3_k127_2729461_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 395.0
HKD3_k127_2729461_1 SpoIVB peptidase S55 K00973,K02414,K21449 - 2.7.7.24 0.00000000000000002681 88.0
HKD3_k127_2729707_0 Belongs to the glycosyl hydrolase 2 family - - - 0.0 1194.0
HKD3_k127_2729707_1 metallopeptidase activity K01179 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0010383,GO:0010410,GO:0010411,GO:0016052,GO:0016787,GO:0016798,GO:0033946,GO:0043170,GO:0044036,GO:0044042,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044264,GO:0044403,GO:0044419,GO:0051704,GO:0052736,GO:0071554,GO:0071704,GO:0085030,GO:1901575,GO:2000895,GO:2000899 3.2.1.4 6.631e-251 788.0
HKD3_k127_2729707_2 symporter activity - - - 2.275e-224 711.0
HKD3_k127_2729707_3 carbohydrate binding K00702 - 2.4.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 453.0
HKD3_k127_2729707_4 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 468.0
HKD3_k127_2729707_5 - - - - 0.00000000000000000008852 96.0
HKD3_k127_2729707_6 DoxX - - - 0.00008782 48.0
HKD3_k127_2755570_0 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 382.0
HKD3_k127_2755570_1 Zn peptidase - - - 0.0000000000000000000000000000000000000000000000000000000001402 219.0
HKD3_k127_2755570_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000004791 175.0
HKD3_k127_2755570_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000007551 122.0
HKD3_k127_2755570_4 RDD family - - - 0.0000000338 66.0
HKD3_k127_2768275_0 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 361.0
HKD3_k127_2768275_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001292 286.0
HKD3_k127_2768275_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000001285 165.0
HKD3_k127_276828_0 PFAM Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 556.0
HKD3_k127_276828_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 443.0
HKD3_k127_276828_2 Arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000001207 137.0
HKD3_k127_276828_3 - - - - 0.0000004217 59.0
HKD3_k127_2773256_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1140.0
HKD3_k127_2773256_1 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 390.0
HKD3_k127_2773256_2 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 358.0
HKD3_k127_2773256_3 ATP:ADP antiporter activity K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002275 287.0
HKD3_k127_2773256_4 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000004445 211.0
HKD3_k127_2773256_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000097 192.0
HKD3_k127_2773256_6 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000931 176.0
HKD3_k127_2773256_7 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000001355 160.0
HKD3_k127_2773256_8 DNA-templated transcription, initiation K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0010565,GO:0016020,GO:0019216,GO:0019217,GO:0019222,GO:0030312,GO:0031323,GO:0044464,GO:0050789,GO:0050794,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090 - 0.000000000000000000000008472 108.0
HKD3_k127_2773256_9 Anti-sigma-K factor rskA K18682 - - 0.0000000000004988 80.0
HKD3_k127_2779387_0 GMC oxidoreductase - - - 2.47e-248 777.0
HKD3_k127_2779387_1 Alpha amylase, catalytic domain - - - 6.136e-209 660.0
HKD3_k127_2779387_10 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 418.0
HKD3_k127_2779387_11 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005168 361.0
HKD3_k127_2779387_12 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 316.0
HKD3_k127_2779387_13 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
HKD3_k127_2779387_14 - K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000009013 244.0
HKD3_k127_2779387_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000007717 231.0
HKD3_k127_2779387_16 pyrroloquinoline quinone binding K12349 - 3.5.1.23 0.000000000000000000000000000000000000000000000000000000000005199 228.0
HKD3_k127_2779387_17 - - - - 0.0000000000000000000000000000000000000194 154.0
HKD3_k127_2779387_18 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000007574 140.0
HKD3_k127_2779387_19 TIGRFAM VWFA-related Acidobacterial domain - - - 0.0000000000000000000000004268 121.0
HKD3_k127_2779387_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 6.251e-205 653.0
HKD3_k127_2779387_20 Protein of unknown function (DUF1442) - - - 0.00000000000000000001341 101.0
HKD3_k127_2779387_21 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000172 96.0
HKD3_k127_2779387_3 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 593.0
HKD3_k127_2779387_4 BNR repeat-like domain K01186 - 3.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003709 514.0
HKD3_k127_2779387_5 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 500.0
HKD3_k127_2779387_6 TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 496.0
HKD3_k127_2779387_7 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 503.0
HKD3_k127_2779387_8 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 477.0
HKD3_k127_2779387_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 477.0
HKD3_k127_2783607_0 transporter, DctM subunit K11690 - - 3.767e-208 665.0
HKD3_k127_2783607_1 TRAP transporter T-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 303.0
HKD3_k127_2783607_2 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001044 284.0
HKD3_k127_2783607_3 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000001613 269.0
HKD3_k127_2783607_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002911 253.0
HKD3_k127_2783607_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000001817 181.0
HKD3_k127_2783607_6 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000005674 82.0
HKD3_k127_2783607_7 Cysteine synthase K01738 - 2.5.1.47 0.000000000000004571 80.0
HKD3_k127_2787818_0 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 293.0
HKD3_k127_2787818_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004828 280.0
HKD3_k127_2787818_10 myo-inosose-2 dehydratase activity - - - 0.000000000000001519 77.0
HKD3_k127_2787818_11 Domain of unknown function (DUF4440) - - - 0.0000001506 63.0
HKD3_k127_2787818_12 SnoaL-like domain - - - 0.000006019 58.0
HKD3_k127_2787818_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002903 268.0
HKD3_k127_2787818_3 MreB/Mbl protein K03569 - - 0.00000000000000000000000000000000000000000000000000000001259 211.0
HKD3_k127_2787818_4 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000000000000000000000000001061 176.0
HKD3_k127_2787818_5 Rnk N-terminus K06140 - - 0.0000000000000000000000000000000000000000000002634 170.0
HKD3_k127_2787818_7 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000001059 131.0
HKD3_k127_2787818_8 polysaccharide lyase family 8 K19049 - 4.2.2.5 0.000000000000000000000000000661 126.0
HKD3_k127_2799863_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.407e-199 644.0
HKD3_k127_2799863_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 453.0
HKD3_k127_2799863_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000001511 230.0
HKD3_k127_2799863_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000002808 205.0
HKD3_k127_2799863_4 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000001009 163.0
HKD3_k127_2799863_5 Conserved hypothetical protein 95 - - - 0.0000000000000000000000000000000000000183 153.0
HKD3_k127_2799863_6 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00006017 53.0
HKD3_k127_2801898_0 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 365.0
HKD3_k127_2801898_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000625 243.0
HKD3_k127_2801898_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000114 127.0
HKD3_k127_2803768_0 Flagellar basal body protein FlaE K02390 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009666 295.0
HKD3_k127_2803768_1 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000006872 76.0
HKD3_k127_2803768_2 PFAM flagellar hook-length control K02414 - - 0.00001027 58.0
HKD3_k127_284604_0 Involved in the tonB-independent uptake of proteins - - - 3.786e-200 652.0
HKD3_k127_284604_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004486 432.0
HKD3_k127_284604_2 Pyridoxal-phosphate dependent enzyme K01754,K17989 - 4.3.1.17,4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 351.0
HKD3_k127_284604_3 COG2939 Carboxypeptidase C (cathepsin A) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 325.0
HKD3_k127_284604_4 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 326.0
HKD3_k127_284604_5 - - - - 0.00000000000000000000000000000000000003587 149.0
HKD3_k127_2858405_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 498.0
HKD3_k127_2858405_1 ECF sigma factor K03088 - - 0.000000000000000000007163 98.0
HKD3_k127_2859273_0 alpha-L-rhamnosidase - - - 1.058e-263 847.0
HKD3_k127_2859273_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 5.619e-253 790.0
HKD3_k127_2859273_2 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 600.0
HKD3_k127_2859273_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 511.0
HKD3_k127_2859273_4 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 516.0
HKD3_k127_2859273_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 394.0
HKD3_k127_2859273_6 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 406.0
HKD3_k127_2859273_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003833 216.0
HKD3_k127_2859273_8 Protein of unknown function (DUF1698) - - - 0.000000000000000000000000000000000009486 151.0
HKD3_k127_2876304_0 Radical SAM - - - 3.542e-212 677.0
HKD3_k127_2876304_1 Peptidase M1, membrane alanine aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 377.0
HKD3_k127_2876304_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 301.0
HKD3_k127_2876304_3 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002743 283.0
HKD3_k127_2876304_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005814 255.0
HKD3_k127_2876304_5 Phospholipid methyltransferase - - - 0.000000000000000000000000000001082 132.0
HKD3_k127_2876304_6 nucleotide metabolic process - - - 0.00000000000000000000000006805 117.0
HKD3_k127_2876304_7 - - - - 0.0000000001748 70.0
HKD3_k127_2881153_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 306.0
HKD3_k127_2881153_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000003427 225.0
HKD3_k127_2881153_2 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000001769 118.0
HKD3_k127_2881153_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K21142 - 2.8.1.12 0.0000000000000008686 80.0
HKD3_k127_288307_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 359.0
HKD3_k127_288307_1 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
HKD3_k127_288307_10 Thioredoxin domain - - - 0.000000000000000000108 94.0
HKD3_k127_288307_11 Sodium Bile acid symporter family K03325 - - 0.0000000000000000007337 87.0
HKD3_k127_288307_2 OsmC-like protein - - - 0.00000000000000000000000000000000000000009616 158.0
HKD3_k127_288307_3 - - - - 0.000000000000000000000000000000004885 134.0
HKD3_k127_288307_4 DGC domain - - - 0.00000000000000000000000000001278 128.0
HKD3_k127_288307_5 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000006268 127.0
HKD3_k127_288307_6 PFAM regulatory protein, ArsR K03892 - - 0.000000000000000000000000001689 116.0
HKD3_k127_288307_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000003837 118.0
HKD3_k127_288307_8 DGC domain - - - 0.00000000000000000006751 97.0
HKD3_k127_288307_9 transcriptional regulator, ArsR family protein K03892 - - 0.00000000000000000008651 94.0
HKD3_k127_2893471_0 Heat shock 70 kDa protein K04043 - - 1.117e-222 706.0
HKD3_k127_2893471_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.256e-205 654.0
HKD3_k127_2893471_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000001921 198.0
HKD3_k127_2893471_11 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000002158 194.0
HKD3_k127_2893471_12 DNA polymerase III, delta subunit, C terminal K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000003869 201.0
HKD3_k127_2893471_13 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000007583 152.0
HKD3_k127_2893471_14 GrpE K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000402 143.0
HKD3_k127_2893471_15 integral membrane protein - - - 0.000000000000000000000000000000008005 135.0
HKD3_k127_2893471_16 Hfq protein - - - 0.0000000000000000000000000000001562 128.0
HKD3_k127_2893471_17 - - - - 0.000000000000000000002294 104.0
HKD3_k127_2893471_18 DUF167 K09131 - - 0.000000000000002613 80.0
HKD3_k127_2893471_19 Type IV pilus biogenesis stability protein PilW - - - 0.00000003399 60.0
HKD3_k127_2893471_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 497.0
HKD3_k127_2893471_3 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 442.0
HKD3_k127_2893471_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 430.0
HKD3_k127_2893471_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 408.0
HKD3_k127_2893471_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000004443 271.0
HKD3_k127_2893471_7 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000001606 271.0
HKD3_k127_2893471_8 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000001403 249.0
HKD3_k127_2893471_9 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000002065 228.0
HKD3_k127_2913333_0 Putative esterase K07214 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 309.0
HKD3_k127_2913333_1 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006961 276.0
HKD3_k127_2913333_2 Domain of unknown function (DUF4118) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009478 271.0
HKD3_k127_2913333_3 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001386 244.0
HKD3_k127_2940292_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 1.373e-219 691.0
HKD3_k127_2940292_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.842e-212 677.0
HKD3_k127_2940292_10 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 313.0
HKD3_k127_2940292_11 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 309.0
HKD3_k127_2940292_12 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001024 278.0
HKD3_k127_2940292_13 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004651 245.0
HKD3_k127_2940292_14 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000001178 219.0
HKD3_k127_2940292_15 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000003901 177.0
HKD3_k127_2940292_16 AIR carboxylase K11808 - 4.1.1.21 0.000000000000000000000000000000000000003985 153.0
HKD3_k127_2940292_17 4'-phosphopantetheinyl transferase superfamily K00997 - 2.7.8.7 0.00000000000000000000000000004037 120.0
HKD3_k127_2940292_18 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000004742 106.0
HKD3_k127_2940292_19 PFAM Integral membrane protein DUF92 - GO:0005575,GO:0016020 - 0.000000000000000000001944 101.0
HKD3_k127_2940292_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 499.0
HKD3_k127_2940292_20 UbiA prenyltransferase family K12501 - 2.5.1.117 0.00000000000000000001052 103.0
HKD3_k127_2940292_21 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000002141 99.0
HKD3_k127_2940292_22 RNA-binding protein K06346 - - 0.0000000000000000001099 94.0
HKD3_k127_2940292_23 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000009811 90.0
HKD3_k127_2940292_24 Polymer-forming cytoskeletal - - - 0.000000000000000008302 91.0
HKD3_k127_2940292_25 - - - - 0.00000000000001215 78.0
HKD3_k127_2940292_26 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000006237 72.0
HKD3_k127_2940292_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 453.0
HKD3_k127_2940292_4 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 425.0
HKD3_k127_2940292_5 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 398.0
HKD3_k127_2940292_6 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 394.0
HKD3_k127_2940292_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 389.0
HKD3_k127_2940292_8 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 338.0
HKD3_k127_2940292_9 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 333.0
HKD3_k127_296758_0 Parallel beta-helix repeats - - - 5.027e-280 874.0
HKD3_k127_296758_1 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 430.0
HKD3_k127_296758_10 - - - - 0.0000000000000000000000004475 111.0
HKD3_k127_296758_11 - - - - 0.000000000000000002202 94.0
HKD3_k127_296758_2 WD40-like Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 427.0
HKD3_k127_296758_3 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 415.0
HKD3_k127_296758_4 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 392.0
HKD3_k127_296758_5 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 392.0
HKD3_k127_296758_6 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 353.0
HKD3_k127_296758_7 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002353 334.0
HKD3_k127_296758_8 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000002213 124.0
HKD3_k127_296758_9 hydrolase, CocE NonD family K06978 - - 0.0000000000000000000000000004665 116.0
HKD3_k127_297316_0 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 1.099e-314 978.0
HKD3_k127_297316_1 Peptidase S46 - - - 1.878e-283 885.0
HKD3_k127_297316_10 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003324 214.0
HKD3_k127_297316_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000007986 154.0
HKD3_k127_297316_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000002964 147.0
HKD3_k127_297316_13 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000000000731 139.0
HKD3_k127_297316_14 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000001588 120.0
HKD3_k127_297316_2 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 550.0
HKD3_k127_297316_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 517.0
HKD3_k127_297316_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 425.0
HKD3_k127_297316_5 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 372.0
HKD3_k127_297316_7 Sensor diguanylate cyclase, PAS domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 342.0
HKD3_k127_297316_8 transmembrane transporter activity K03535 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002731 292.0
HKD3_k127_297316_9 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003857 284.0
HKD3_k127_2984197_0 proline dipeptidase activity K01262,K01271 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000005818 272.0
HKD3_k127_2984197_1 ABC-type transport system involved in cytochrome c biogenesis, permease component K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000001316 236.0
HKD3_k127_2984197_2 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000002928 151.0
HKD3_k127_29932_0 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 407.0
HKD3_k127_29932_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 311.0
HKD3_k127_29932_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000001965 217.0
HKD3_k127_29932_3 Domain of unknown function (DUF4832) - - - 0.00000000000000000000000000000000000000005032 156.0
HKD3_k127_2999834_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 345.0
HKD3_k127_2999834_1 Protein of unknown function (DUF2911) - - - 0.000000000002998 73.0
HKD3_k127_304498_0 Involved in the tonB-independent uptake of proteins K03641 - - 1.307e-231 744.0
HKD3_k127_304498_1 Histidine kinase-like ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 341.0
HKD3_k127_304498_2 transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.00000000000000000000971 95.0
HKD3_k127_304498_3 - - - - 0.0000000000000001961 90.0
HKD3_k127_304498_4 PFAM Peptidase family M23 - - - 0.00000000000001263 83.0
HKD3_k127_30491_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 3.258e-263 850.0
HKD3_k127_30491_1 xylulokinase activity K00848,K00851,K00854 - 2.7.1.12,2.7.1.17,2.7.1.5 0.00000000000000000000000000000000000000000000000000002125 192.0
HKD3_k127_30491_2 PFAM Stage II sporulation - - - 0.00000000000000000000000000000000000000000001278 188.0
HKD3_k127_3079521_0 dipeptidyl-peptidase activity K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 623.0
HKD3_k127_3079521_1 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 539.0
HKD3_k127_3079521_2 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000001485 158.0
HKD3_k127_3079521_3 Protein of unknown function (DUF2847) - - - 0.0000000000000000009543 91.0
HKD3_k127_3079521_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0005693 43.0
HKD3_k127_3091118_0 TonB-dependent Receptor Plug Domain K02014 - - 4.26e-200 649.0
HKD3_k127_3091118_1 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 426.0
HKD3_k127_3091118_2 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 308.0
HKD3_k127_3091118_3 ornithine cyclodeaminase activity K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000007115 274.0
HKD3_k127_3091118_4 Carboxypeptidase regulatory-like domain - - - 0.00000004928 66.0
HKD3_k127_3091118_5 TonB-dependent receptor K02014 - - 0.0001673 53.0
HKD3_k127_3103529_0 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 600.0
HKD3_k127_3103529_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 572.0
HKD3_k127_3103529_2 - - - - 0.00000000000000000000000000000000000000000000000000003012 196.0
HKD3_k127_3103529_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000002069 173.0
HKD3_k127_3103529_4 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000001481 156.0
HKD3_k127_3103529_5 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.000000000000000000000000000000000000001857 155.0
HKD3_k127_3103529_6 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000003546 149.0
HKD3_k127_3103529_7 WD40-like Beta Propeller - - - 0.00000000000000000000000000000002704 128.0
HKD3_k127_3103529_8 - - - - 0.000000001106 61.0
HKD3_k127_3103529_9 HDOD domain - - - 0.000005772 51.0
HKD3_k127_311346_0 Phage Terminase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 465.0
HKD3_k127_311346_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 471.0
HKD3_k127_311346_2 terminase, small subunit - - - 0.0000000000000000000000000000001208 129.0
HKD3_k127_311346_3 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000008028 96.0
HKD3_k127_311346_4 - - - - 0.000000006119 60.0
HKD3_k127_3115007_0 Amino acid permease - - - 4.784e-241 768.0
HKD3_k127_3115007_1 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 489.0
HKD3_k127_3115007_2 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 399.0
HKD3_k127_3115007_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006263 385.0
HKD3_k127_3115007_4 BON domain - - - 0.0000000000000000000000000000004849 136.0
HKD3_k127_3115007_5 - - - - 0.0000000000000000000000000001133 121.0
HKD3_k127_3115007_6 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000002814 107.0
HKD3_k127_3115007_7 RNA-binding protein - - - 0.000000000000000000002553 99.0
HKD3_k127_313614_0 CAAX protease self-immunity K07052 - - 1.236e-232 761.0
HKD3_k127_313614_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000004235 216.0
HKD3_k127_313614_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000005481 153.0
HKD3_k127_313614_3 Protein conserved in bacteria - - - 0.000000000000000000000001077 107.0
HKD3_k127_3150832_0 MotA/TolQ/ExbB proton channel family K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 286.0
HKD3_k127_3150832_1 Membrane MotB of proton-channel complex MotA/MotB K02557 - - 0.000000000000000000000000000000000000000000000000000000006733 208.0
HKD3_k127_3150832_2 acid synthase K01654 - 2.5.1.56 0.0000000000000007543 83.0
HKD3_k127_3150832_3 PFAM flagellar FlbD family protein K02385 - - 0.0000000008054 63.0
HKD3_k127_3150832_4 FR47-like protein - - - 0.0000005163 55.0
HKD3_k127_3278936_0 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 325.0
HKD3_k127_3278936_1 Protein of unknown function (DUF3750) - - - 0.0000000000000000000000000000000000000000000000000000000008236 209.0
HKD3_k127_3278936_2 carbohydrate transport - - - 0.00000000000000000000000000437 117.0
HKD3_k127_3278936_3 inositol 2-dehydrogenase activity - - - 0.000000000001206 71.0
HKD3_k127_3278936_4 Pilus assembly protein, PilP - - - 0.000000000001886 72.0
HKD3_k127_3278936_5 Integrase - - - 0.0000000007831 61.0
HKD3_k127_3324018_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 518.0
HKD3_k127_3324018_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 459.0
HKD3_k127_3324018_2 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 398.0
HKD3_k127_3325200_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 521.0
HKD3_k127_3325200_1 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 392.0
HKD3_k127_3325200_2 - - - - 0.0000000004122 62.0
HKD3_k127_3333981_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 3.305e-321 993.0
HKD3_k127_3333981_11 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000001362 88.0
HKD3_k127_3333981_2 Isocitrate/isopropylmalate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 594.0
HKD3_k127_3333981_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 454.0
HKD3_k127_3333981_4 Belongs to the GHMP kinase family. GalK subfamily K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 459.0
HKD3_k127_3333981_5 Glycosyl hydrolases family 2, sugar binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 422.0
HKD3_k127_3333981_6 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 366.0
HKD3_k127_3333981_7 PFAM Stage II sporulation E family protein - - - 0.000000000000000000000000000000000000000000000000000000000000004534 225.0
HKD3_k127_3333981_8 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000002545 212.0
HKD3_k127_3333981_9 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000006926 173.0
HKD3_k127_3335451_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 562.0
HKD3_k127_3335451_1 ABC transporter K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 458.0
HKD3_k127_3335451_10 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000001242 199.0
HKD3_k127_3335451_11 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10794 - 1.21.4.1 0.0000000000000000000000000000000000006755 152.0
HKD3_k127_3335451_12 - - - - 0.0000000000000000007006 96.0
HKD3_k127_3335451_13 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000000003857 62.0
HKD3_k127_3335451_14 Predicted membrane protein (DUF2085) - - - 0.000000003048 65.0
HKD3_k127_3335451_2 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 394.0
HKD3_k127_3335451_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 385.0
HKD3_k127_3335451_4 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 373.0
HKD3_k127_3335451_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004066 284.0
HKD3_k127_3335451_6 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005284 280.0
HKD3_k127_3335451_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001232 270.0
HKD3_k127_3335451_8 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000001303 245.0
HKD3_k127_3335451_9 Domain of unknown function (DUF1732) - - - 0.0000000000000000000000000000000000000000000000000000000133 209.0
HKD3_k127_3372016_0 Domain of unknown function - - - 1.371e-228 719.0
HKD3_k127_3372016_1 Belongs to the glycosyl hydrolase 31 family K07407 - 3.2.1.22 2.117e-212 679.0
HKD3_k127_3372016_10 Beta-lactamase superfamily domain - - - 0.00000000000000000002879 102.0
HKD3_k127_3372016_11 Ppx/GppA phosphatase family K15442 - - 0.0002416 44.0
HKD3_k127_3372016_2 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 419.0
HKD3_k127_3372016_3 arylsulfatase A K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 397.0
HKD3_k127_3372016_4 Domain of unknown function (DUF5107) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 385.0
HKD3_k127_3372016_5 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 344.0
HKD3_k127_3372016_6 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 330.0
HKD3_k127_3372016_7 exodeoxyribonuclease I activity K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 310.0
HKD3_k127_3372016_8 competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001327 244.0
HKD3_k127_3372016_9 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000002071 103.0
HKD3_k127_33731_0 polysaccharide deacetylase - - - 4.206e-307 970.0
HKD3_k127_33731_1 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 2.961e-219 694.0
HKD3_k127_33731_10 - - - - 0.00000000000000000007599 94.0
HKD3_k127_33731_11 succinate dehydrogenase activity K00242,K00246 - - 0.00000000002218 69.0
HKD3_k127_33731_12 Protein of unknown function (DUF2950) - - - 0.0000000006756 61.0
HKD3_k127_33731_2 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 492.0
HKD3_k127_33731_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 383.0
HKD3_k127_33731_4 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000005686 274.0
HKD3_k127_33731_5 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.00000000000000000000000000000000000000000000000000000000000000000005932 241.0
HKD3_k127_33731_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000004057 234.0
HKD3_k127_33731_7 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000007155 147.0
HKD3_k127_33731_8 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000002487 133.0
HKD3_k127_33731_9 Putative zinc-finger - - - 0.0000000000000000000003573 98.0
HKD3_k127_3373940_0 Short chain dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 598.0
HKD3_k127_3373940_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 514.0
HKD3_k127_3373940_10 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000002173 165.0
HKD3_k127_3373940_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000001781 146.0
HKD3_k127_3373940_12 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.000000000000000000000000000000000001937 153.0
HKD3_k127_3373940_13 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000006202 110.0
HKD3_k127_3373940_14 Trm112p-like protein K09791 - - 0.00000000000000000003071 91.0
HKD3_k127_3373940_15 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000002294 75.0
HKD3_k127_3373940_16 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00008874 46.0
HKD3_k127_3373940_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 447.0
HKD3_k127_3373940_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000836 430.0
HKD3_k127_3373940_4 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000557 384.0
HKD3_k127_3373940_5 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 355.0
HKD3_k127_3373940_6 Domain of unknown function (DUF3488) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001039 303.0
HKD3_k127_3373940_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000002297 192.0
HKD3_k127_3373940_8 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000006446 192.0
HKD3_k127_3373940_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000005453 173.0
HKD3_k127_3406226_0 synthetase, class II (G H P K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 304.0
HKD3_k127_3406226_1 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000997 224.0
HKD3_k127_3406226_2 TPR repeat-containing protein - - - 0.00000000001307 72.0
HKD3_k127_3406226_3 - - - - 0.00006978 55.0
HKD3_k127_347356_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 548.0
HKD3_k127_347356_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 456.0
HKD3_k127_347356_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000002395 164.0
HKD3_k127_347356_3 Protein of unknown function (DUF2911) - - - 0.0000000000013 70.0
HKD3_k127_3480801_0 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 606.0
HKD3_k127_3480801_1 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000363 218.0
HKD3_k127_3480801_2 SpoU rRNA Methylase - - - 0.000000000000000000000000000000000000000000000000000000000001824 217.0
HKD3_k127_3504691_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 442.0
HKD3_k127_3504691_1 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 317.0
HKD3_k127_3541552_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.888e-256 809.0
HKD3_k127_3541552_1 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000003114 229.0
HKD3_k127_3541552_2 Hemerythrin HHE cation binding - - - 0.0000000000000000000000000000000005291 141.0
HKD3_k127_3541552_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000463 100.0
HKD3_k127_3541552_4 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000000002827 79.0
HKD3_k127_3541552_5 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.000000000009346 68.0
HKD3_k127_3541552_7 T5orf172 - - - 0.0002689 46.0
HKD3_k127_35965_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008114 523.0
HKD3_k127_35965_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000000000008383 198.0
HKD3_k127_35965_2 Amidohydrolase K07045 - - 0.00000000000000000000008307 109.0
HKD3_k127_35965_3 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000009228 79.0
HKD3_k127_35965_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000002352 82.0
HKD3_k127_3611093_0 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 4.294e-202 636.0
HKD3_k127_3611093_1 PFAM PfkB K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 458.0
HKD3_k127_3611093_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 445.0
HKD3_k127_3611093_3 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 390.0
HKD3_k127_3611093_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 239.0
HKD3_k127_3611093_5 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000001192 201.0
HKD3_k127_3611093_6 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000003624 158.0
HKD3_k127_3611093_7 agmatine deiminase activity K08589,K10536 GO:0003674,GO:0003824,GO:0004175,GO:0004197,GO:0004198,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0016787,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.22.37,3.5.3.12 0.000000000000000000000000000000008322 142.0
HKD3_k127_3611093_8 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000002463 87.0
HKD3_k127_3615020_0 Cytochrome c5530 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 595.0
HKD3_k127_3615020_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 460.0
HKD3_k127_3615020_10 von Willebrand factor, type A K07114 - - 0.00000000000000000000000007126 119.0
HKD3_k127_3615020_11 GTP binding - - - 0.0000000000004221 74.0
HKD3_k127_3615020_12 Ami_3 K01448 - 3.5.1.28 0.0000008643 60.0
HKD3_k127_3615020_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 323.0
HKD3_k127_3615020_3 Glycosyl hydrolase family 20, catalytic domain K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000003423 244.0
HKD3_k127_3615020_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000002062 180.0
HKD3_k127_3615020_5 - - - - 0.0000000000000000000000000000000000000001308 175.0
HKD3_k127_3615020_6 Methyltransferase - - - 0.0000000000000000000000000000000000000004504 158.0
HKD3_k127_3615020_7 competence protein - - - 0.0000000000000000000000000000008889 132.0
HKD3_k127_3615020_8 PFAM Bacterial regulatory protein, arsR family - - - 0.00000000000000000000000000003384 120.0
HKD3_k127_3615020_9 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000001365 111.0
HKD3_k127_3638915_0 - - - - 2.628e-206 665.0
HKD3_k127_3638915_1 Glycosyl hydrolase family 20, domain 2 - - - 0.000000000000000000000000000000000000000000000000003886 190.0
HKD3_k127_3638915_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000001141 98.0
HKD3_k127_3641117_0 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002465 295.0
HKD3_k127_3643078_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 1.756e-251 814.0
HKD3_k127_3643078_1 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 514.0
HKD3_k127_3643078_2 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 335.0
HKD3_k127_3643078_3 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003268 237.0
HKD3_k127_3643078_4 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000003288 229.0
HKD3_k127_3643078_5 GtrA-like protein - - - 0.000000000000000000000000003625 116.0
HKD3_k127_3643078_8 YacP-like NYN domain K06962 - - 0.00004741 51.0
HKD3_k127_3645606_0 PFAM peptidase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 360.0
HKD3_k127_3645606_1 Mate efflux family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 325.0
HKD3_k127_3645606_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007261 280.0
HKD3_k127_3645606_3 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000001171 190.0
HKD3_k127_3645606_4 Protein of unknown function (DUF2911) - - - 0.000000000000000000003885 101.0
HKD3_k127_3648473_0 malic enzyme K00027,K00029 - 1.1.1.38,1.1.1.40 3.17e-216 694.0
HKD3_k127_3648473_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 612.0
HKD3_k127_3648473_2 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 367.0
HKD3_k127_3648473_3 Pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.0000000000000000000000000000000001269 156.0
HKD3_k127_3648473_4 Pfam:N_methyl_2 - - - 0.000000006079 64.0
HKD3_k127_3648473_5 Pyruvate phosphate dikinase, PEP pyruvate binding domain K01007 - 2.7.9.2 0.0002679 55.0
HKD3_k127_3657622_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 399.0
HKD3_k127_3657622_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 306.0
HKD3_k127_3657622_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 296.0
HKD3_k127_3657622_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000005569 122.0
HKD3_k127_3657622_4 nuclear chromosome segregation - - - 0.0000001658 62.0
HKD3_k127_3658739_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 418.0
HKD3_k127_3658739_1 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006372 295.0
HKD3_k127_3658739_2 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001838 268.0
HKD3_k127_3658739_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001182 254.0
HKD3_k127_3658739_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000002414 94.0
HKD3_k127_3658739_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000001389 90.0
HKD3_k127_3658739_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.000000000000004313 78.0
HKD3_k127_3658739_7 Putative zinc-finger - - - 0.000003269 57.0
HKD3_k127_3659794_0 NADH dehydrogenase - - - 2.872e-230 728.0
HKD3_k127_3659794_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 346.0
HKD3_k127_3659794_10 DRTGG domain - - - 0.0000000000000000000000000007137 117.0
HKD3_k127_3659794_11 DRTGG domain - - - 0.000000000000000000000002318 114.0
HKD3_k127_3659794_12 iron hydrogenase, small subunit K00336 - 1.6.5.3 0.000001111 59.0
HKD3_k127_3659794_2 Putative Fe-S cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 329.0
HKD3_k127_3659794_3 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 301.0
HKD3_k127_3659794_4 PHP-associated K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000001463 229.0
HKD3_k127_3659794_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000004087 177.0
HKD3_k127_3659794_6 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000000000001329 162.0
HKD3_k127_3659794_7 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000002518 175.0
HKD3_k127_3659794_8 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.000000000000000000000000000000000000000144 154.0
HKD3_k127_3659794_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000007905 158.0
HKD3_k127_3659925_0 Belongs to the glycosyl hydrolase 3 family K05349,K17641 - 3.2.1.21 9.048e-209 672.0
HKD3_k127_3659925_1 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 347.0
HKD3_k127_3659925_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009038 337.0
HKD3_k127_3659925_3 Major Facilitator Superfamily - - - 0.0000000006841 62.0
HKD3_k127_3671446_0 DNA Topoisomerase IV K02469 - 5.99.1.3 1.227e-205 655.0
HKD3_k127_3671446_1 Metalloenzyme superfamily K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006429 477.0
HKD3_k127_3671446_2 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 421.0
HKD3_k127_3671446_3 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 331.0
HKD3_k127_3671446_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000003158 219.0
HKD3_k127_3671446_5 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.000000000000000000004241 94.0
HKD3_k127_3671446_6 - - - - 0.0000000001984 71.0
HKD3_k127_3693881_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.59e-291 933.0
HKD3_k127_3693881_1 Zinc carboxypeptidase - - - 3.531e-230 741.0
HKD3_k127_3693881_10 PFAM YbbR family protein - - - 0.0000000000000000001112 100.0
HKD3_k127_3693881_11 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000003206 83.0
HKD3_k127_3693881_2 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 559.0
HKD3_k127_3693881_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 407.0
HKD3_k127_3693881_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000002674 236.0
HKD3_k127_3693881_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000001836 201.0
HKD3_k127_3693881_6 Catalyzes the phosphorylation of D-glycero-D-manno- heptose 7-phosphate at the C-1 position to selectively form D- glycero-beta-D-manno-heptose-1,7-bisphosphate K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000479 182.0
HKD3_k127_3693881_7 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000001728 165.0
HKD3_k127_3693881_8 peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000000000000000000001589 147.0
HKD3_k127_3693881_9 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000004002 123.0
HKD3_k127_3704104_0 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 1.648e-215 683.0
HKD3_k127_3704104_1 Tricorn protease PDZ domain - - - 2.517e-214 680.0
HKD3_k127_3704104_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 2.546e-200 635.0
HKD3_k127_3704104_3 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 452.0
HKD3_k127_3704262_0 Peptidase S46 - - - 1.673e-275 863.0
HKD3_k127_3704262_1 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 319.0
HKD3_k127_3704262_2 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001351 264.0
HKD3_k127_3704262_3 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000008819 153.0
HKD3_k127_3712299_0 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 469.0
HKD3_k127_3712299_1 Fumarylacetoacetate (FAA) hydrolase K14259 - 4.2.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005587 285.0
HKD3_k127_3712299_2 methyltransferase K13311,K13326,K21335 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983 2.1.1.234 0.0000000000000000000000000000000000000003875 150.0
HKD3_k127_3712701_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 3.055e-199 628.0
HKD3_k127_3712701_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 383.0
HKD3_k127_3712701_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 346.0
HKD3_k127_3712701_3 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000002924 176.0
HKD3_k127_3712701_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000001035 138.0
HKD3_k127_3712701_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000008439 126.0
HKD3_k127_3712701_6 CYTH K05873 - 4.6.1.1 0.000000000000000000001114 102.0
HKD3_k127_3712701_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00001373 56.0
HKD3_k127_371428_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 571.0
HKD3_k127_371428_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000183 447.0
HKD3_k127_371428_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 322.0
HKD3_k127_371428_3 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000007064 259.0
HKD3_k127_3722223_0 Filamentation induced by cAMP protein fic - - - 7.437e-247 771.0
HKD3_k127_3722223_1 - - - - 0.0000000000000000000000000000000001087 143.0
HKD3_k127_3722223_2 NHL repeat - - - 0.00000000000000000001676 97.0
HKD3_k127_3722223_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000002456 79.0
HKD3_k127_3722223_4 amine dehydrogenase activity K08884 - 2.7.11.1 0.0000000003393 66.0
HKD3_k127_3739446_0 ThiC-associated domain K03147 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007045 498.0
HKD3_k127_3739446_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 340.0
HKD3_k127_3739446_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000003238 155.0
HKD3_k127_3748633_0 beta-galactosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 551.0
HKD3_k127_3748633_1 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 526.0
HKD3_k127_3748633_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 514.0
HKD3_k127_3748633_3 PFAM peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 457.0
HKD3_k127_3748633_4 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K10716 - - 0.000000000000000000000000000000000000000000000000002216 196.0
HKD3_k127_3748633_5 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000001812 156.0
HKD3_k127_3748633_6 - - - - 0.0000000000000000000000000000000001134 138.0
HKD3_k127_3748633_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000008232 61.0
HKD3_k127_374977_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 604.0
HKD3_k127_374977_1 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 575.0
HKD3_k127_374977_2 COG1651 Protein-disulfide isomerase - - - 0.0000000000001394 79.0
HKD3_k127_374977_3 Hep Hag repeat protein - - - 0.0000001887 65.0
HKD3_k127_3773271_0 Glycogen debranching enzyme K05989 - 3.2.1.40 0.0 1212.0
HKD3_k127_3773271_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 622.0
HKD3_k127_3773271_10 - - - - 0.00004587 46.0
HKD3_k127_3773271_11 Helix-turn-helix domain - - - 0.0002281 47.0
HKD3_k127_3773271_2 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002535 484.0
HKD3_k127_3773271_3 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 397.0
HKD3_k127_3773271_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 377.0
HKD3_k127_3773271_5 PFAM glycoside hydrolase, family 10 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 334.0
HKD3_k127_3773271_6 3' exoribonuclease family, domain 2 K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 302.0
HKD3_k127_3773271_7 Belongs to the glycosyl hydrolase 2 family - - - 0.0000000000000000000000000000000000000000000000000000000003137 206.0
HKD3_k127_3773271_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000001751 184.0
HKD3_k127_3793773_0 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 538.0
HKD3_k127_3793773_1 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 396.0
HKD3_k127_3793773_2 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 383.0
HKD3_k127_3793773_3 Protein of unknown function (DUF1343) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 351.0
HKD3_k127_3793773_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003763 271.0
HKD3_k127_3793773_5 permease - - - 0.00000000000000000000000000000000000000000000000000005775 201.0
HKD3_k127_3802342_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007139 461.0
HKD3_k127_3802342_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 441.0
HKD3_k127_3802342_10 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000001285 143.0
HKD3_k127_3802342_11 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000002284 102.0
HKD3_k127_3802342_12 Outer membrane protein assembly complex, YaeT protein K07277 - - 0.000001115 56.0
HKD3_k127_3802342_13 Evidence 5 No homology to any previously reported sequences - - - 0.00000745 54.0
HKD3_k127_3802342_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 430.0
HKD3_k127_3802342_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008322 376.0
HKD3_k127_3802342_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 349.0
HKD3_k127_3802342_5 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 351.0
HKD3_k127_3802342_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 322.0
HKD3_k127_3802342_7 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 307.0
HKD3_k127_3802342_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 306.0
HKD3_k127_3802342_9 ZIP Zinc transporter K07238,K16267 - - 0.000000000000000000000000000000000000000000000000000000000002812 217.0
HKD3_k127_3833321_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term K17108 - 3.2.1.45 0.0 1023.0
HKD3_k127_3833321_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 377.0
HKD3_k127_3833321_2 phosphorelay sensor kinase activity K07711,K14980,K18143 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000415 265.0
HKD3_k127_3833898_0 ATPase associated with various cellular K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 460.0
HKD3_k127_3833898_1 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 352.0
HKD3_k127_3833898_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000409 346.0
HKD3_k127_3833898_3 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006808 340.0
HKD3_k127_3833898_4 von Willebrand factor (vWF) type A domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003263 276.0
HKD3_k127_3833898_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004128 276.0
HKD3_k127_3833898_6 Tetratricopeptide repeat - - - 0.00000000000003482 83.0
HKD3_k127_3833898_7 - - - - 0.00000000000006058 84.0
HKD3_k127_3855572_0 COGs COG4299 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 583.0
HKD3_k127_3855572_1 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 539.0
HKD3_k127_3855572_2 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 427.0
HKD3_k127_3855572_3 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 387.0
HKD3_k127_3855572_4 HpcH/HpaI aldolase/citrate lyase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000001301 256.0
HKD3_k127_3855572_5 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000000000000000000000000005794 199.0
HKD3_k127_3855572_6 Mechanosensitive ion channel - - - 0.0001045 54.0
HKD3_k127_3899182_0 Domain of unknown function (DUF4968) K01811 - 3.2.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 501.0
HKD3_k127_3899182_1 TrkA-N domain K11745 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 400.0
HKD3_k127_3899182_2 Flavodoxin-like fold K11748 - - 0.00000000000000000000000000000000000000000000000000000000000000002861 229.0
HKD3_k127_3911797_0 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 354.0
HKD3_k127_3911797_1 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 307.0
HKD3_k127_3911797_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000004571 227.0
HKD3_k127_3911797_3 N-acylglucosamine 2-epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000002647 228.0
HKD3_k127_3911797_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000006119 187.0
HKD3_k127_3911797_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000007563 146.0
HKD3_k127_3911797_6 Oxidoreductase K03810 - - 0.000000000000000000000002349 115.0
HKD3_k127_3911797_7 cell redox homeostasis K03671 - - 0.000000000000001526 83.0
HKD3_k127_3913015_0 Dihydrodipicolinate synthetase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 445.0
HKD3_k127_3913015_1 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 433.0
HKD3_k127_3913015_2 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 415.0
HKD3_k127_3913015_3 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 405.0
HKD3_k127_3913015_4 Aldose 1-epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004302 402.0
HKD3_k127_3913015_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 318.0
HKD3_k127_3913015_6 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 307.0
HKD3_k127_3928752_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 363.0
HKD3_k127_3928752_1 Bacillithiol biosynthesis BshC K22136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 307.0
HKD3_k127_3928752_2 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008628 278.0
HKD3_k127_3928752_3 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000000004505 211.0
HKD3_k127_3970707_0 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000002051 190.0
HKD3_k127_3970707_1 ACT domain K03567 - - 0.000000000000000000000000000000000000001626 154.0
HKD3_k127_3970707_2 Ami_3 K01448 - 3.5.1.28 0.000005196 57.0
HKD3_k127_3973224_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 591.0
HKD3_k127_3973224_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000003874 123.0
HKD3_k127_3973307_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009345 537.0
HKD3_k127_3973307_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 515.0
HKD3_k127_3973307_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000001432 176.0
HKD3_k127_3985024_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000004377 217.0
HKD3_k127_3987283_0 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 489.0
HKD3_k127_3987283_1 GHMP kinases C terminal K16190 - 2.7.1.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 365.0
HKD3_k127_3987283_10 Universal stress protein - - - 0.000000000000000000000004448 113.0
HKD3_k127_3987283_2 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 332.0
HKD3_k127_3987283_3 PFAM peptidase M4 thermolysin K08603 - 3.4.24.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002163 277.0
HKD3_k127_3987283_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000179 274.0
HKD3_k127_3987283_5 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002792 276.0
HKD3_k127_3987283_6 alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001825 268.0
HKD3_k127_3987283_7 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000004735 197.0
HKD3_k127_3987283_8 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000005343 184.0
HKD3_k127_3987283_9 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000001556 165.0
HKD3_k127_3994276_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 424.0
HKD3_k127_3994276_1 Glycosyl hydrolase family 57 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 429.0
HKD3_k127_4035020_0 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000002071 143.0
HKD3_k127_4035020_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000001131 126.0
HKD3_k127_4038338_0 secondary active sulfate transmembrane transporter activity K06901 - - 7.008e-214 676.0
HKD3_k127_4038338_1 carboxylic acid catabolic process K01684 - 4.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 596.0
HKD3_k127_4038338_2 COGs COG0673 dehydrogenase and related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 357.0
HKD3_k127_4038338_3 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 322.0
HKD3_k127_4038338_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000004317 111.0
HKD3_k127_4038338_5 Phosphoesterase family K21302 GO:0003674,GO:0003824,GO:0003993,GO:0004438,GO:0004805,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006139,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006742,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009109,GO:0009117,GO:0009166,GO:0009987,GO:0016310,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019203,GO:0019362,GO:0019364,GO:0019438,GO:0019439,GO:0019637,GO:0030258,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046486,GO:0046488,GO:0046496,GO:0046700,GO:0046834,GO:0046854,GO:0050189,GO:0050192,GO:0051186,GO:0051187,GO:0052744,GO:0052866,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072526,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.3.64 0.000000006051 59.0
HKD3_k127_4051197_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 2.439e-224 707.0
HKD3_k127_4051197_1 Sigma-70, region 4 K03088 - - 0.00000000000000000000000006103 115.0
HKD3_k127_4051197_2 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000003047 70.0
HKD3_k127_4051197_3 Domain of unknown function (DUF4349) - - - 0.000002715 56.0
HKD3_k127_4085645_0 CoA-substrate-specific enzyme activase - - - 0.0 1317.0
HKD3_k127_4085645_1 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008208 601.0
HKD3_k127_4085645_10 oxidase subunit K08738 - - 0.0000000000000000000018 106.0
HKD3_k127_4085645_11 EamA-like transporter family - - - 0.00000000000000002425 94.0
HKD3_k127_4085645_12 PFAM Methylamine - - - 0.000000000000003463 81.0
HKD3_k127_4085645_13 DSBA-like thioredoxin domain - - - 0.00000000000008357 79.0
HKD3_k127_4085645_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 422.0
HKD3_k127_4085645_3 Cytochrome bd terminal oxidase subunit I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 352.0
HKD3_k127_4085645_4 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 318.0
HKD3_k127_4085645_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 258.0
HKD3_k127_4085645_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000001859 242.0
HKD3_k127_4085645_7 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000044 199.0
HKD3_k127_4085645_9 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000004148 149.0
HKD3_k127_4107925_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 307.0
HKD3_k127_4107925_1 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
HKD3_k127_4107925_2 PFAM response regulator receiver - - - 0.00000000000000000000000000000000004279 142.0
HKD3_k127_4107925_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000003278 137.0
HKD3_k127_4107925_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000003684 89.0
HKD3_k127_4107925_5 AntiSigma factor - - - 0.00006085 53.0
HKD3_k127_4116804_0 PFAM SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 405.0
HKD3_k127_4116804_1 COGs COG0673 dehydrogenase and related protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 415.0
HKD3_k127_4116804_2 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000001345 197.0
HKD3_k127_4116804_3 aminopeptidase activity K19689 - - 0.0000000000000000000000000000000000000000000000000002248 199.0
HKD3_k127_4116804_4 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000008313 152.0
HKD3_k127_4116804_5 Transglycosylase associated protein - - - 0.00000000000000000000000000002693 119.0
HKD3_k127_4116804_6 Domain of Unknown Function (DUF1080) - - - 0.0000000000000006062 78.0
HKD3_k127_4152198_0 Large extracellular alpha-helical protein K06894 - - 0.0 1941.0
HKD3_k127_4152198_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 6.404e-208 672.0
HKD3_k127_4152198_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 554.0
HKD3_k127_4152198_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 498.0
HKD3_k127_4152198_4 G3E family - - - 0.000000000000000000000000000000000000000000000000000000006766 211.0
HKD3_k127_4152198_5 Xylose isomerase-like TIM barrel - - - 0.00000000000006798 72.0
HKD3_k127_4152211_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 0.0 1024.0
HKD3_k127_4152211_1 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 1.553e-238 767.0
HKD3_k127_4152211_10 ubiE/COQ5 methyltransferase family - - - 0.0001622 51.0
HKD3_k127_4152211_11 - - - - 0.0005497 51.0
HKD3_k127_4152211_2 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
HKD3_k127_4152211_3 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) K16213 - 5.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000002223 278.0
HKD3_k127_4152211_4 Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion K02564 - 3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002991 254.0
HKD3_k127_4152211_5 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000414 247.0
HKD3_k127_4152211_6 PFAM DoxX K15977 - - 0.00000000000000000000000000000000001219 145.0
HKD3_k127_4152211_7 inositol 2-dehydrogenase activity - - - 0.000000000000000000000007836 102.0
HKD3_k127_4152211_8 TROVE domain - - - 0.0000000000000004786 78.0
HKD3_k127_4152211_9 Calcineurin-like phosphoesterase superfamily domain K03651 - 3.1.4.53 0.000000003393 69.0
HKD3_k127_4195077_0 - - - - 2.321e-222 704.0
HKD3_k127_4195077_1 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.000000000000000000000000000000000000000000000000000000000009115 219.0
HKD3_k127_4195077_2 Glycerophosphoryl diester phosphodiesterase family K01126 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0008081,GO:0008889,GO:0009279,GO:0016020,GO:0016787,GO:0016788,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044462,GO:0044464,GO:0046872,GO:0071944 3.1.4.46 0.00000000007094 67.0
HKD3_k127_4202388_0 Belongs to the glycosyl hydrolase 31 family K01187 - 3.2.1.20 1.083e-205 653.0
HKD3_k127_4202388_1 Belongs to the glycosyl hydrolase 32 family K03332 - 3.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 567.0
HKD3_k127_4202388_10 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000004914 62.0
HKD3_k127_4202388_11 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000199 63.0
HKD3_k127_4202388_12 Arsenical pump membrane protein - - - 0.000001265 51.0
HKD3_k127_4202388_13 WD40 domain protein beta Propeller - - - 0.0000179 53.0
HKD3_k127_4202388_14 toxin-antitoxin pair type II binding K19156 - - 0.0005679 45.0
HKD3_k127_4202388_2 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 437.0
HKD3_k127_4202388_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 393.0
HKD3_k127_4202388_4 - - - - 0.000000000000000000000000000000000000000000000000000000000002488 218.0
HKD3_k127_4202388_5 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000003195 185.0
HKD3_k127_4202388_7 ECF sigma factor - - - 0.0000000000000000000000000009162 115.0
HKD3_k127_4202388_8 PIN domain - - - 0.000000000000000000000004368 110.0
HKD3_k127_4202388_9 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000001472 102.0
HKD3_k127_4208553_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.86e-207 654.0
HKD3_k127_4208553_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 473.0
HKD3_k127_4208553_2 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000001615 187.0
HKD3_k127_4208553_3 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K08137 - - 0.0000000000000017 76.0
HKD3_k127_4209672_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 621.0
HKD3_k127_4209672_1 Belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 524.0
HKD3_k127_4209672_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003895 378.0
HKD3_k127_4209672_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000007283 243.0
HKD3_k127_4209672_4 Amidohydrolase family - - - 0.000000000000000000000000000000000007354 145.0
HKD3_k127_4209672_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000000000000000000000000000000009174 136.0
HKD3_k127_4209672_6 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000003742 127.0
HKD3_k127_4209672_7 Amidohydrolase family - - - 0.00000000000000000000008855 103.0
HKD3_k127_4209672_8 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000001157 72.0
HKD3_k127_4229717_0 - - - - 2.789e-294 923.0
HKD3_k127_4229717_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 602.0
HKD3_k127_4229717_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000175 123.0
HKD3_k127_4229717_11 - - - - 0.0000005681 59.0
HKD3_k127_4229717_12 aldo keto reductase - - - 0.000002443 50.0
HKD3_k127_4229717_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004651 581.0
HKD3_k127_4229717_3 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 366.0
HKD3_k127_4229717_4 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 314.0
HKD3_k127_4229717_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 302.0
HKD3_k127_4229717_6 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002382 275.0
HKD3_k127_4229717_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000001739 236.0
HKD3_k127_4229717_8 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000002861 186.0
HKD3_k127_4229717_9 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000009479 131.0
HKD3_k127_4230240_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 370.0
HKD3_k127_4230240_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 330.0
HKD3_k127_4230240_2 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000222 192.0
HKD3_k127_4270148_0 MacB-like periplasmic core domain - - - 1.114e-309 972.0
HKD3_k127_4270148_1 Insecticidal toxin complex protein TcaC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 403.0
HKD3_k127_4270148_2 - - - - 0.0000000000000000000000000002978 125.0
HKD3_k127_4270148_3 - - - - 0.0000000000000244 78.0
HKD3_k127_4270148_4 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.00000000000002886 84.0
HKD3_k127_4270148_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000009248 80.0
HKD3_k127_4270148_7 PFAM Polysaccharide deacetylase - - - 0.0001219 55.0
HKD3_k127_4300433_0 GTP-binding protein TypA K06207 - - 2.529e-268 838.0
HKD3_k127_4300433_1 Methionine gamma-lyase K01739 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 575.0
HKD3_k127_4300433_2 CYTH - - - 0.00000000000000000000000000000000000000000000000000000000000001356 224.0
HKD3_k127_4300433_3 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000000007299 177.0
HKD3_k127_4300433_4 - - - - 0.000000000000000000000000000000006036 130.0
HKD3_k127_4300433_5 LytTr DNA-binding domain K02477 - - 0.0000000000001741 78.0
HKD3_k127_433071_0 beta-galactosidase activity - - - 3.21e-219 687.0
HKD3_k127_433071_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 315.0
HKD3_k127_433071_2 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000002574 238.0
HKD3_k127_433071_3 xyloglucan:xyloglucosyl transferase activity - - - 0.000000000000000000000000000000000000000002019 171.0
HKD3_k127_433071_4 Phospholipase B - - - 0.0000000000000000000000008046 107.0
HKD3_k127_433071_5 AMP binding - - - 0.000000001097 64.0
HKD3_k127_435832_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 399.0
HKD3_k127_435832_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 367.0
HKD3_k127_435832_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002037 293.0
HKD3_k127_435832_3 alkyl hydroperoxide reductase K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006950,GO:0006979,GO:0007154,GO:0008150,GO:0008152,GO:0009267,GO:0009321,GO:0009605,GO:0009636,GO:0009970,GO:0009987,GO:0009991,GO:0010033,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0030003,GO:0031667,GO:0031668,GO:0031669,GO:0032843,GO:0032991,GO:0033194,GO:0033195,GO:0033212,GO:0033214,GO:0033554,GO:0042221,GO:0042592,GO:0042594,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051716,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071496,GO:0097237,GO:0098754,GO:0098771,GO:0098869,GO:1901700,GO:1902494,GO:1990204,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000005193 256.0
HKD3_k127_435832_4 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000000008023 211.0
HKD3_k127_435832_5 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000477 123.0
HKD3_k127_435832_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000006532 114.0
HKD3_k127_435832_7 Belongs to the UPF0597 family - - - 0.000000000009105 68.0
HKD3_k127_4365223_0 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 437.0
HKD3_k127_4365223_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 325.0
HKD3_k127_4365223_2 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000000000000000000000000000000000000004188 165.0
HKD3_k127_4365223_3 transmembrane transporter activity - - - 0.0002688 44.0
HKD3_k127_4387797_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000002199 234.0
HKD3_k127_4387797_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000001395 103.0
HKD3_k127_4387797_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000001748 113.0
HKD3_k127_4387797_4 Sporulation related domain - - - 0.0001974 54.0
HKD3_k127_43911_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 479.0
HKD3_k127_43911_1 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 381.0
HKD3_k127_43911_2 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 307.0
HKD3_k127_43911_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003868 278.0
HKD3_k127_43911_4 NADH dehydrogenase K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002142 267.0
HKD3_k127_43911_5 Thioredoxin-like [2Fe-2S] ferredoxin K05586 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000002395 193.0
HKD3_k127_43911_6 cheY-homologous receiver domain K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000000000000000000000000000000000000000000006161 190.0
HKD3_k127_43911_7 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000000000000000000000000001854 141.0
HKD3_k127_43911_8 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000001038 115.0
HKD3_k127_442016_0 HlyD family secretion protein K02005 - - 0.000000000000000000000000000000005533 144.0
HKD3_k127_442016_1 HlyD membrane-fusion protein of T1SS - - - 0.0001025 53.0
HKD3_k127_4565330_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 432.0
HKD3_k127_4565330_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 359.0
HKD3_k127_4565330_2 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 256.0
HKD3_k127_4565330_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000002301 160.0
HKD3_k127_4611106_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 522.0
HKD3_k127_4611106_1 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 381.0
HKD3_k127_4611106_2 isomerase K02082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 353.0
HKD3_k127_4611106_3 PFAM Xylose isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 299.0
HKD3_k127_4611106_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00004143 54.0
HKD3_k127_4639771_0 Putative esterase - - - 1.61e-202 635.0
HKD3_k127_4639771_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 504.0
HKD3_k127_4639771_2 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 378.0
HKD3_k127_4639771_3 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 327.0
HKD3_k127_4639771_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000007029 182.0
HKD3_k127_4639771_5 PFAM Cold-shock K03704 - - 0.0000000000000000000000000004418 113.0
HKD3_k127_4639771_6 Methyltransferase domain - - - 0.000000000000000000000006332 111.0
HKD3_k127_4639771_7 Ankyrin repeat and KH K16726 GO:0001654,GO:0001745,GO:0001751,GO:0001754,GO:0002376,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007005,GO:0007010,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007169,GO:0007275,GO:0007399,GO:0007423,GO:0008150,GO:0009605,GO:0009607,GO:0009653,GO:0009887,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010506,GO:0010507,GO:0010639,GO:0010821,GO:0010823,GO:0010927,GO:0010941,GO:0016043,GO:0019222,GO:0019730,GO:0019899,GO:0019900,GO:0019901,GO:0022008,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030182,GO:0030239,GO:0031032,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031430,GO:0031672,GO:0031674,GO:0032501,GO:0032502,GO:0032989,GO:0033043,GO:0040011,GO:0042692,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043207,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0044085,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0045087,GO:0045214,GO:0046530,GO:0048468,GO:0048513,GO:0048519,GO:0048523,GO:0048592,GO:0048646,GO:0048699,GO:0048731,GO:0048749,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051129,GO:0051146,GO:0051704,GO:0051707,GO:0051716,GO:0055001,GO:0055002,GO:0060361,GO:0060548,GO:0061061,GO:0065007,GO:0070925,GO:0071840,GO:0090596,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:1903146,GO:1903147 - 0.0000000000004103 76.0
HKD3_k127_4656598_0 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 403.0
HKD3_k127_4656598_1 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007486 267.0
HKD3_k127_4656598_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000001398 237.0
HKD3_k127_4719007_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009251 297.0
HKD3_k127_4719007_1 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005147 286.0
HKD3_k127_4719007_2 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000006649 193.0
HKD3_k127_4760864_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 584.0
HKD3_k127_4760864_1 Glycosyl hydrolase family 20, domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 463.0
HKD3_k127_4760864_2 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 292.0
HKD3_k127_47747_0 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 463.0
HKD3_k127_47747_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 459.0
HKD3_k127_47747_10 Tetratricopeptide repeat - - - 0.000000000002014 80.0
HKD3_k127_47747_11 - - - - 0.000000001358 70.0
HKD3_k127_47747_12 - - - - 0.00000001182 67.0
HKD3_k127_47747_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 447.0
HKD3_k127_47747_3 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 396.0
HKD3_k127_47747_4 O-GlcNAcase BT_4395 K01197 GO:0003674,GO:0003824,GO:0004553,GO:0004563,GO:0005488,GO:0005515,GO:0005975,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015929,GO:0016231,GO:0016787,GO:0016798,GO:0019538,GO:0036211,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901135,GO:1901564 3.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 392.0
HKD3_k127_47747_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000005686 177.0
HKD3_k127_47747_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000005738 184.0
HKD3_k127_47747_7 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000000000000000006265 188.0
HKD3_k127_47747_8 transport - - - 0.00000000000000000000000000003316 123.0
HKD3_k127_47747_9 Tetratricopeptide repeat - - - 0.0000000000000000000003319 113.0
HKD3_k127_4795503_0 peptidyl-tyrosine sulfation - - - 3.366e-197 635.0
HKD3_k127_4795503_1 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 432.0
HKD3_k127_4795503_2 COG COG0383 Alpha-mannosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 355.0
HKD3_k127_4795503_3 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 342.0
HKD3_k127_4795503_4 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000000000000002401 175.0
HKD3_k127_4795503_5 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.000000000000000009449 94.0
HKD3_k127_4839531_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 426.0
HKD3_k127_4839531_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 399.0
HKD3_k127_4839531_2 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 351.0
HKD3_k127_4839531_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 292.0
HKD3_k127_4839531_4 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000002855 183.0
HKD3_k127_4859966_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 542.0
HKD3_k127_4859966_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 464.0
HKD3_k127_4859966_2 inositol 2-dehydrogenase activity K18106 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 392.0
HKD3_k127_4859966_3 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 381.0
HKD3_k127_4859966_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004854 271.0
HKD3_k127_4859966_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000001856 241.0
HKD3_k127_4866076_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.009e-210 670.0
HKD3_k127_4866076_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1.807e-196 625.0
HKD3_k127_4866076_2 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 451.0
HKD3_k127_4866076_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 293.0
HKD3_k127_4878390_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.2.1.113 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 416.0
HKD3_k127_4878390_1 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 374.0
HKD3_k127_4878390_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 309.0
HKD3_k127_4878390_3 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000000000003684 218.0
HKD3_k127_4882414_0 unfolded protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 481.0
HKD3_k127_4889238_0 polygalacturonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 497.0
HKD3_k127_4889238_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 410.0
HKD3_k127_4889238_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004625 243.0
HKD3_k127_4889238_3 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000001314 256.0
HKD3_k127_4904228_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 1.125e-267 837.0
HKD3_k127_4904228_1 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009841 464.0
HKD3_k127_4904228_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 426.0
HKD3_k127_4904228_3 serine-type peptidase activity K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 410.0
HKD3_k127_4904228_4 serine-type peptidase activity K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 366.0
HKD3_k127_4904228_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003398 267.0
HKD3_k127_4904228_6 His Kinase A (phosphoacceptor) domain K02484,K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000006092 267.0
HKD3_k127_4904228_7 nuclease activity K18828 - - 0.000000000000000003819 91.0
HKD3_k127_4904228_8 response to nickel cation - - - 0.0000000000001209 74.0
HKD3_k127_4905272_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1244.0
HKD3_k127_4905272_1 SMART Resolvase, RNase H domain protein fold K06959 - - 1.222e-202 658.0
HKD3_k127_4905272_2 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 482.0
HKD3_k127_4905272_3 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 391.0
HKD3_k127_4905272_4 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000001151 253.0
HKD3_k127_4905272_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000000000000000001012 197.0
HKD3_k127_4905272_6 multi-organism process - - - 0.00000000000000000000000000000000000005903 154.0
HKD3_k127_4905272_7 Nickel-dependent hydrogenase - - - 0.00000001832 56.0
HKD3_k127_4905272_8 Protein of unknown function (DUF2911) - - - 0.0005446 45.0
HKD3_k127_4906799_0 Glycine radical K00656,K07540,K20038 - 2.3.1.54,4.1.99.11,4.3.99.4 0.0 1215.0
HKD3_k127_4906799_1 PfkB domain protein K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 611.0
HKD3_k127_4906799_10 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 335.0
HKD3_k127_4906799_11 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
HKD3_k127_4906799_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003814 263.0
HKD3_k127_4906799_13 ABC 3 transport family K02075,K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000102 253.0
HKD3_k127_4906799_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001005 233.0
HKD3_k127_4906799_15 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.00000000000000000000000000000000000000000000000000000000000000001844 237.0
HKD3_k127_4906799_16 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000007426 224.0
HKD3_k127_4906799_17 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000005424 228.0
HKD3_k127_4906799_18 - - - - 0.000000000000000000000000000000000000000000000000000000000000002873 228.0
HKD3_k127_4906799_19 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000001747 218.0
HKD3_k127_4906799_2 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 537.0
HKD3_k127_4906799_20 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000004431 140.0
HKD3_k127_4906799_21 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000000001633 132.0
HKD3_k127_4906799_22 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000007849 143.0
HKD3_k127_4906799_23 Phosphopantetheine attachment site - - - 0.0000000000002127 72.0
HKD3_k127_4906799_24 Regulatory protein, FmdB family - - - 0.0000000000364 67.0
HKD3_k127_4906799_25 - - - - 0.0002508 50.0
HKD3_k127_4906799_3 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 529.0
HKD3_k127_4906799_4 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 476.0
HKD3_k127_4906799_5 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 466.0
HKD3_k127_4906799_6 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 488.0
HKD3_k127_4906799_7 Domain of unknown function (DUF5009) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 413.0
HKD3_k127_4906799_8 synthase K16167 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 394.0
HKD3_k127_4906799_9 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 333.0
HKD3_k127_4914332_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190,K05350,K12308 - 3.2.1.21,3.2.1.23 5.681e-256 808.0
HKD3_k127_4914332_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003503 527.0
HKD3_k127_4914332_2 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 380.0
HKD3_k127_4914332_3 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 340.0
HKD3_k127_4914332_4 Acyltransferase family K11941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 301.0
HKD3_k127_4914332_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002286 232.0
HKD3_k127_4914332_6 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000002299 198.0
HKD3_k127_4914332_7 Putative esterase - - - 0.0000000000000000000000000000000000000000006048 172.0
HKD3_k127_4914332_8 Histidine kinase K02478 - 2.7.13.3 0.00000000000000000000000000000001946 134.0
HKD3_k127_4915146_0 carbohydrate binding K00702 - 2.4.1.20 0.0 1009.0
HKD3_k127_4915146_1 Domain of unknown function (DUF4968) K01811 - 3.2.1.177 0.000000000005922 70.0
HKD3_k127_4951749_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 491.0
HKD3_k127_4954726_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K00533 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.7.2 5.191e-211 669.0
HKD3_k127_4954726_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 523.0
HKD3_k127_4954726_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007613 433.0
HKD3_k127_4954726_3 Hydrogenase (NiFe) small subunit HydA K00534,K06282,K18008 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.7.2,1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 374.0
HKD3_k127_4954726_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000004889 192.0
HKD3_k127_4954726_5 PFAM peptidase M52 hydrogen uptake protein K03605 - - 0.000000000000000000000000000000000000000000003816 170.0
HKD3_k127_4954726_6 Protein of unknown function (DUF2905) - - - 0.00000000000004926 74.0
HKD3_k127_4954726_7 protein tyrosine kinase activity K03593 - - 0.00003149 46.0
HKD3_k127_4964086_0 Prolyl oligopeptidase family - - - 1.596e-266 836.0
HKD3_k127_4964086_1 serine threonine protein kinase K12132 - 2.7.11.1 7.483e-240 773.0
HKD3_k127_4964086_10 DoxX K16937 - 1.8.5.2 0.00000000000000000000000000000000000000003791 170.0
HKD3_k127_4964086_11 radical SAM domain protein - - - 0.0000000000000000000000000000000000000003438 170.0
HKD3_k127_4964086_12 Belongs to the peptidase S8 family - - - 0.000000000000001376 87.0
HKD3_k127_4964086_13 Reeler domain - - - 0.000000000000006909 87.0
HKD3_k127_4964086_15 TIGRFAM Bacteriochlorophyll chlorophyll synthetase K04040 - 2.5.1.133,2.5.1.62 0.000009482 57.0
HKD3_k127_4964086_2 MacB-like periplasmic core domain - - - 8.816e-216 696.0
HKD3_k127_4964086_3 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 588.0
HKD3_k127_4964086_4 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 476.0
HKD3_k127_4964086_5 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 410.0
HKD3_k127_4964086_6 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 375.0
HKD3_k127_4964086_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K00380,K03734 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0016020,GO:0016740,GO:0017013,GO:0019538,GO:0030288,GO:0030313,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0031975,GO:0036094,GO:0036211,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0071944,GO:0071949,GO:0097159,GO:0098552,GO:0098567,GO:1901265,GO:1901363,GO:1901564 1.8.1.2,2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005608 289.0
HKD3_k127_4964086_8 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000003727 175.0
HKD3_k127_4964086_9 Lysin motif - - - 0.000000000000000000000000000000000000000001048 160.0
HKD3_k127_4973031_0 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 7.198e-312 967.0
HKD3_k127_4973031_1 Radical SAM - - - 0.000000000000000000000000000000000000931 140.0
HKD3_k127_4979671_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1374.0
HKD3_k127_4979671_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.000000000000000000000000000000000000000000000000002147 187.0
HKD3_k127_4992256_0 Predicted Permease Membrane Region K07085 - - 1.48e-212 674.0
HKD3_k127_4992256_1 Beta-Casp domain K07576 - - 6.124e-196 620.0
HKD3_k127_4992256_2 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 500.0
HKD3_k127_4992256_3 Phosphate acetyl/butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 464.0
HKD3_k127_4992256_4 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 421.0
HKD3_k127_4992256_5 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 417.0
HKD3_k127_4992256_6 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000004764 222.0
HKD3_k127_4992256_7 Ion channel - - - 0.0007745 42.0
HKD3_k127_5004599_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 434.0
HKD3_k127_5004599_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 398.0
HKD3_k127_5004599_2 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 386.0
HKD3_k127_5004599_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003886 347.0
HKD3_k127_5004599_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000147 179.0
HKD3_k127_5009222_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 4.24e-299 925.0
HKD3_k127_5009222_1 Belongs to the carbamoyltransferase HypF family K04656 - - 2.151e-273 863.0
HKD3_k127_5009222_10 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000002944 97.0
HKD3_k127_5009222_2 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006714 560.0
HKD3_k127_5009222_3 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 311.0
HKD3_k127_5009222_4 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 259.0
HKD3_k127_5009222_5 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002039 255.0
HKD3_k127_5009222_6 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000001764 195.0
HKD3_k127_5009222_7 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000001067 153.0
HKD3_k127_5009222_8 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000008234 133.0
HKD3_k127_5009222_9 carbon dioxide binding K04653 - - 0.00000000000000000000000003261 110.0
HKD3_k127_5011636_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2207.0
HKD3_k127_5011636_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 6.76e-229 723.0
HKD3_k127_5011636_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969,K03574 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18,3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 508.0
HKD3_k127_5011636_3 GMC oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 399.0
HKD3_k127_5011636_4 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 345.0
HKD3_k127_5011636_5 PFAM AhpC TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 289.0
HKD3_k127_5014047_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1125.0
HKD3_k127_5014047_1 Belongs to the IlvD Edd family K22396 - 4.2.1.82 2.449e-288 898.0
HKD3_k127_5014047_10 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002331 279.0
HKD3_k127_5014047_11 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000224 267.0
HKD3_k127_5014047_12 dehydrogenases and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000667 264.0
HKD3_k127_5014047_13 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002506 252.0
HKD3_k127_5014047_14 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000006654 165.0
HKD3_k127_5014047_15 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000001726 158.0
HKD3_k127_5014047_16 TonB dependent receptor K02014,K16087 - - 0.000000000000000000000000000000000000000006322 178.0
HKD3_k127_5014047_17 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.0000000000000000000000000000000000000003546 157.0
HKD3_k127_5014047_18 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000001609 121.0
HKD3_k127_5014047_19 Alpha/beta hydrolase family - - - 0.000000000000001108 89.0
HKD3_k127_5014047_2 serine-type peptidase activity K01278 - 3.4.14.5 5.651e-225 720.0
HKD3_k127_5014047_3 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003146 595.0
HKD3_k127_5014047_4 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 406.0
HKD3_k127_5014047_5 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 398.0
HKD3_k127_5014047_6 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 390.0
HKD3_k127_5014047_7 PFAM Nucleotidyl transferase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 328.0
HKD3_k127_5014047_8 Insulinase (Peptidase family M16) K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 325.0
HKD3_k127_5014047_9 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 310.0
HKD3_k127_5014239_0 Dihydroorotate dehydrogenase - - - 3.067e-253 808.0
HKD3_k127_5014239_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 481.0
HKD3_k127_5014239_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 323.0
HKD3_k127_5014239_3 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009413 274.0
HKD3_k127_5014239_4 - - - - 0.000000000000000000001224 104.0
HKD3_k127_5033486_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1159.0
HKD3_k127_5033486_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.323e-255 812.0
HKD3_k127_5033486_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000599 150.0
HKD3_k127_5033486_11 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000214 143.0
HKD3_k127_5033486_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000002957 132.0
HKD3_k127_5033486_13 Involved in chromosome partitioning - - - 0.00000000000000000000000000000001177 140.0
HKD3_k127_5033486_14 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000002167 137.0
HKD3_k127_5033486_15 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000004052 126.0
HKD3_k127_5033486_16 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000000000000002843 82.0
HKD3_k127_5033486_17 Carboxymuconolactone decarboxylase family - - - 0.000000004419 62.0
HKD3_k127_5033486_18 Oxygen tolerance - - - 0.0002953 54.0
HKD3_k127_5033486_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.976e-200 636.0
HKD3_k127_5033486_3 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 488.0
HKD3_k127_5033486_4 Glycosyltransferase like family 2 K10012 - 2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 376.0
HKD3_k127_5033486_5 Domain present in PSD-95, Dlg, and ZO-1/2. K08070,K08372 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 310.0
HKD3_k127_5033486_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000003272 241.0
HKD3_k127_5033486_7 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000007931 199.0
HKD3_k127_5033486_8 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000001494 174.0
HKD3_k127_5033486_9 amino acid transport K02029,K02030 - - 0.00000000000000000000000000000000000002668 158.0
HKD3_k127_5034591_0 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000001478 200.0
HKD3_k127_5034591_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000005469 149.0
HKD3_k127_5034591_2 PFAM Uncharacterised BCR, COG1649 K05988 - 3.2.1.11 0.000000001902 67.0
HKD3_k127_5036529_0 Carboxypeptidase regulatory-like domain - - - 0.0 1246.0
HKD3_k127_5036529_1 Alpha-L-arabinofuranosidase C-terminal domain K01209 - 3.2.1.55 1.042e-212 673.0
HKD3_k127_5036529_10 PFAM NUDIX hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000978 226.0
HKD3_k127_5036529_11 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000006231 202.0
HKD3_k127_5036529_12 Domain of unknown function (DUF4872) - - - 0.000000000000000000000000000000000000000000000000008258 193.0
HKD3_k127_5036529_13 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000000000000000000007074 172.0
HKD3_k127_5036529_14 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.0000000000000000000000000000000000000000003179 170.0
HKD3_k127_5036529_15 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000003677 126.0
HKD3_k127_5036529_16 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000003912 109.0
HKD3_k127_5036529_17 Trehalose utilisation K09992 - - 0.00000000000000233 77.0
HKD3_k127_5036529_18 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000116 76.0
HKD3_k127_5036529_19 Methyltransferase domain - - - 0.00000000000003436 81.0
HKD3_k127_5036529_2 beta-galactosidase activity - - - 1.348e-203 646.0
HKD3_k127_5036529_3 Hypothetical glycosyl hydrolase 6 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 591.0
HKD3_k127_5036529_4 COG3119 Arylsulfatase A K01134 - 3.1.6.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 572.0
HKD3_k127_5036529_5 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 500.0
HKD3_k127_5036529_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 505.0
HKD3_k127_5036529_7 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 426.0
HKD3_k127_5036529_8 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004173 322.0
HKD3_k127_5036529_9 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 294.0
HKD3_k127_5036883_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 531.0
HKD3_k127_5036883_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 431.0
HKD3_k127_5036883_2 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 393.0
HKD3_k127_5036883_3 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000001443 237.0
HKD3_k127_5036883_4 YqcI/YcgG family - - - 0.00000000000000000000000000000000000000000000000000001277 197.0
HKD3_k127_5036883_5 Putative transposase - - - 0.00000000000000000000000646 104.0
HKD3_k127_5036883_6 Linear amide C-N hydrolases, choloylglycine hydrolase family - - - 0.00000000000001011 88.0
HKD3_k127_5036883_7 4Fe-4S dicluster domain - - - 0.0000000002006 66.0
HKD3_k127_5036883_8 Putative transposase - - - 0.0003006 46.0
HKD3_k127_5047740_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001559 261.0
HKD3_k127_5047740_1 Oxygen tolerance - - - 0.00000000000000000000000000000000000000000000000000000000002182 222.0
HKD3_k127_5047740_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000003332 138.0
HKD3_k127_5047740_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000228 51.0
HKD3_k127_5050610_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 386.0
HKD3_k127_5050610_1 PFAM short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001731 255.0
HKD3_k127_5050610_2 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000003823 222.0
HKD3_k127_5050610_3 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000007646 136.0
HKD3_k127_505225_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 9.239e-273 854.0
HKD3_k127_505225_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000724 223.0
HKD3_k127_5093258_0 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 490.0
HKD3_k127_5093258_1 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 325.0
HKD3_k127_5093258_2 Membrane - - - 0.00000000000000000000000000000000000000000000007893 185.0
HKD3_k127_5093258_3 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000001344 94.0
HKD3_k127_5110360_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 496.0
HKD3_k127_5110360_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 353.0
HKD3_k127_5110360_2 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 306.0
HKD3_k127_5110360_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004238 245.0
HKD3_k127_5110360_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000005507 254.0
HKD3_k127_5110360_5 TIGRFAM efflux transporter, RND family, MFP subunit K02005 - - 0.00000000000000000000000000000000000000006762 158.0
HKD3_k127_511197_0 Involved in the tonB-independent uptake of proteins K03641 - - 7.949e-248 798.0
HKD3_k127_511197_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 417.0
HKD3_k127_511197_2 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 370.0
HKD3_k127_511197_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 315.0
HKD3_k127_5135840_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 589.0
HKD3_k127_5135840_1 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002579 289.0
HKD3_k127_5135840_2 pfam abc K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001239 282.0
HKD3_k127_5135840_3 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000006989 225.0
HKD3_k127_5135840_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000001086 210.0
HKD3_k127_5135840_5 OsmC-like protein - - - 0.0000000000000000000000000000000000000002504 155.0
HKD3_k127_5135840_6 - - - - 0.000000000000000000000000005539 116.0
HKD3_k127_5135840_8 - - - - 0.0001136 52.0
HKD3_k127_5139489_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.385e-261 818.0
HKD3_k127_5139489_1 Aldo/keto reductase family K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 331.0
HKD3_k127_5139489_2 - - - - 0.0000000000000000001774 90.0
HKD3_k127_5139489_3 Tetratricopeptide repeat protein - - - 0.0000006982 56.0
HKD3_k127_5142379_0 - - - - 1.243e-254 798.0
HKD3_k127_5142379_1 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 427.0
HKD3_k127_5142379_2 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003702 395.0
HKD3_k127_5142379_3 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008438 304.0
HKD3_k127_5142379_4 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000013 227.0
HKD3_k127_5142379_5 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000001284 86.0
HKD3_k127_5148062_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 586.0
HKD3_k127_5148062_1 Carbamoyltransferase C-terminus K00612 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 586.0
HKD3_k127_5148062_10 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000001583 198.0
HKD3_k127_5148062_11 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000009128 199.0
HKD3_k127_5148062_12 nuclear chromosome segregation - - - 0.000000000000000000000000000000000000000000000001762 193.0
HKD3_k127_5148062_13 - - - - 0.0000000000001347 81.0
HKD3_k127_5148062_2 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 584.0
HKD3_k127_5148062_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 516.0
HKD3_k127_5148062_4 3-beta hydroxysteroid dehydrogenase/isomerase family K01710,K08678 - 4.1.1.35,4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 453.0
HKD3_k127_5148062_5 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 423.0
HKD3_k127_5148062_6 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 352.0
HKD3_k127_5148062_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 304.0
HKD3_k127_5148062_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000721 271.0
HKD3_k127_5148062_9 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000489 226.0
HKD3_k127_5151977_0 Poly A polymerase head domain K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007454 428.0
HKD3_k127_5151977_1 Tetratricopeptide repeat - - - 0.00000000008274 74.0
HKD3_k127_5166622_0 - K07138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 591.0
HKD3_k127_5166622_1 NIPSNAP family containing protein - - - 0.00000000000000000000000000000000000000000001008 166.0
HKD3_k127_5166622_2 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000002414 183.0
HKD3_k127_5166622_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000004437 149.0
HKD3_k127_5166622_4 Cytochrome c - - - 0.000803 53.0
HKD3_k127_5166622_5 Galactokinase K18674 GO:0003674,GO:0003824,GO:0004335,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006012,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019318,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046835,GO:0071704 2.7.1.157 0.0009457 52.0
HKD3_k127_5186771_0 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 338.0
HKD3_k127_5186771_1 PFAM Glucuronate isomerase K01812 - 5.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 310.0
HKD3_k127_5186771_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002322 273.0
HKD3_k127_5186771_3 protein conserved in cyanobacteria - - - 0.000000000000000000000000000000001118 135.0
HKD3_k127_5208141_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 1.224e-219 690.0
HKD3_k127_5208141_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 2.198e-205 679.0
HKD3_k127_5208141_10 Putative esterase - - - 0.00000000000000000000000000000000000000003317 166.0
HKD3_k127_5208141_11 O-antigen ligase like membrane protein - - - 0.000000000000000000000000000000000000002795 164.0
HKD3_k127_5208141_12 - - - - 0.0000000000000000000000000000007746 127.0
HKD3_k127_5208141_13 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.0000000000000000000001781 101.0
HKD3_k127_5208141_14 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.00000000001468 68.0
HKD3_k127_5208141_2 UDP binding domain K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006317 550.0
HKD3_k127_5208141_3 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009884 435.0
HKD3_k127_5208141_4 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007118 409.0
HKD3_k127_5208141_5 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 405.0
HKD3_k127_5208141_6 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 349.0
HKD3_k127_5208141_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000125 271.0
HKD3_k127_5208141_8 macromolecule localization K09690 - - 0.000000000000000000000000000000000000000000000000000000000002203 218.0
HKD3_k127_5208141_9 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000003698 221.0
HKD3_k127_5225717_0 Pyridine nucleotide-disulphide oxidoreductase K00335 - 1.6.5.3 2.628e-276 883.0
HKD3_k127_5225717_1 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K05299,K05588 - 1.17.1.10,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 319.0
HKD3_k127_5225717_2 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000004387 149.0
HKD3_k127_5225717_3 coenzyme F420 hydrogenase activity K18007 - 1.12.1.2 0.000000000000001359 78.0
HKD3_k127_5225717_4 CAAX protease self-immunity K07052 - - 0.00000265 58.0
HKD3_k127_5260057_0 - - - - 0.000000000000000000000000000000000000000002473 170.0
HKD3_k127_5260057_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.000000000000000001895 98.0
HKD3_k127_526177_0 PFAM glycoside hydrolase family 3 K05349 - 3.2.1.21 5.531e-309 965.0
HKD3_k127_526177_1 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 1.052e-229 728.0
HKD3_k127_526177_10 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 370.0
HKD3_k127_526177_11 5'-nucleotidase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 293.0
HKD3_k127_526177_12 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006651 276.0
HKD3_k127_526177_13 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
HKD3_k127_526177_14 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000603 227.0
HKD3_k127_526177_15 5'-nucleotidase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000001769 214.0
HKD3_k127_526177_16 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000141 212.0
HKD3_k127_526177_17 Belongs to the 5'-nucleotidase family K01081 - 3.1.3.5 0.000000000000000000000000005453 111.0
HKD3_k127_526177_18 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000002015 124.0
HKD3_k127_526177_19 Lactoylglutathione lyase K05606 - 5.1.99.1 0.00000000000000000000021 108.0
HKD3_k127_526177_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 8.004e-206 651.0
HKD3_k127_526177_20 Transposase IS66 family - - - 0.0000000000000001351 87.0
HKD3_k127_526177_21 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000003524 94.0
HKD3_k127_526177_22 dextransucrase activity - - - 0.000000000002002 70.0
HKD3_k127_526177_3 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005337 599.0
HKD3_k127_526177_4 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 567.0
HKD3_k127_526177_5 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 540.0
HKD3_k127_526177_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 519.0
HKD3_k127_526177_7 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 407.0
HKD3_k127_526177_8 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 387.0
HKD3_k127_526177_9 signal transduction protein containing EAL and modified HD-GYP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 371.0
HKD3_k127_5267156_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005882 384.0
HKD3_k127_5267156_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 294.0
HKD3_k127_5267156_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007485 283.0
HKD3_k127_5284657_0 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 367.0
HKD3_k127_5284657_1 alpha/beta hydrolase fold K07214 - - 0.000000000000000000000000000000000000000000000405 185.0
HKD3_k127_5294208_0 chitin binding K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 396.0
HKD3_k127_5294208_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 355.0
HKD3_k127_5294208_2 Carbohydrate family 9 binding domain-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 317.0
HKD3_k127_5294208_3 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000000000447 222.0
HKD3_k127_5294208_4 Acid phosphatase homologues - - - 0.000000000000000004202 95.0
HKD3_k127_5294208_5 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000122 66.0
HKD3_k127_5298577_0 DNA photolyase activity K03716 - 4.1.99.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 354.0
HKD3_k127_5298577_1 ParB domain protein nuclease K03497 - - 0.000000000000000000000002979 114.0
HKD3_k127_5298577_2 Tetratricopeptide repeat - - - 0.00002951 55.0
HKD3_k127_5298577_3 NUDIX domain K03575 - - 0.0002385 49.0
HKD3_k127_5321446_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 5.914e-247 788.0
HKD3_k127_5321446_1 PQQ-like domain K00114 - 1.1.2.8 7.182e-219 694.0
HKD3_k127_5321446_2 cephalosporin-C deacetylase activity K01061 - 3.1.1.45 2.661e-201 652.0
HKD3_k127_5321446_3 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 455.0
HKD3_k127_5321446_4 2Fe-2S -binding domain K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003908 257.0
HKD3_k127_5321446_5 Putative collagen-binding domain of a collagenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000383 241.0
HKD3_k127_5321446_6 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000001031 216.0
HKD3_k127_5321446_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000001125 141.0
HKD3_k127_5508682_0 beta-galactosidase activity - - - 0.0 1126.0
HKD3_k127_5508682_1 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 381.0
HKD3_k127_5508682_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
HKD3_k127_5515829_0 PFAM lipolytic protein G-D-S-L family K01073 - 3.1.2.20 0.0000000000000000000000000000000000000000000000000002419 197.0
HKD3_k127_5515829_1 LssY C-terminus - - - 0.00000000000000000000003762 102.0
HKD3_k127_5515829_2 phosphorelay sensor kinase activity K07711,K14980,K18143 - 2.7.13.3 0.000000000009932 76.0
HKD3_k127_5515829_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000001443 67.0
HKD3_k127_5516208_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 383.0
HKD3_k127_5516208_1 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 331.0
HKD3_k127_5516208_2 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000007548 220.0
HKD3_k127_5516208_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000006649 193.0
HKD3_k127_5516208_4 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000001242 172.0
HKD3_k127_5516208_5 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000000000004869 70.0
HKD3_k127_5516208_6 deoxyhypusine monooxygenase activity - - - 0.0000009108 60.0
HKD3_k127_5516208_7 PFAM TPR repeat-containing protein - - - 0.0000111 57.0
HKD3_k127_5516208_8 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0001942 49.0
HKD3_k127_552394_0 Phosphoesterase family - - - 1.141e-275 873.0
HKD3_k127_552394_1 MacB-like periplasmic core domain - - - 4.669e-265 833.0
HKD3_k127_552394_2 beta-N-acetylhexosaminidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 430.0
HKD3_k127_552394_3 Serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 328.0
HKD3_k127_552394_4 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 289.0
HKD3_k127_552394_5 - - - - 0.000000000000000000000000000000000000000000000000000000000001857 229.0
HKD3_k127_552394_6 - - - - 0.00000000000000000000000000000000000000000000000000000000001615 216.0
HKD3_k127_552394_7 Flp pilus assembly protein, ATPase CpaE K02282 - - 0.00000000000000000000000000000000000000000000000305 188.0
HKD3_k127_552394_8 - - - - 0.00000000000000000000000000000000000000000000001645 183.0
HKD3_k127_5566326_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000002095 246.0
HKD3_k127_5566326_1 RNA polymerase sigma-70 factor, Planctomycetaceae-specific subfamily 1 K03088 - - 0.00000000000000002936 91.0
HKD3_k127_5566326_2 - - - - 0.00000001864 63.0
HKD3_k127_5681695_0 PFAM GAF domain protein - - - 0.000000000000000000000000000002708 138.0
HKD3_k127_5681695_1 Histidine kinase K07679 - 2.7.13.3 0.000000000000000000000002126 119.0
HKD3_k127_5681695_2 maturation - - - 0.000000000001551 72.0
HKD3_k127_5681695_3 response regulator, receiver - - - 0.000000000004917 72.0
HKD3_k127_575098_0 Glycine cleavage system P-protein K00281 - 1.4.4.2 3.503e-281 879.0
HKD3_k127_575098_1 succinate dehydrogenase - - - 3.327e-237 745.0
HKD3_k127_575098_10 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000001387 99.0
HKD3_k127_575098_11 Dodecin K09165 - - 0.00000000000000000009906 93.0
HKD3_k127_575098_12 lactate racemase activity K22373 - 5.1.2.1 0.000000000005718 66.0
HKD3_k127_575098_13 - - - - 0.000000005736 60.0
HKD3_k127_575098_2 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 513.0
HKD3_k127_575098_3 Ureide permease K05340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 438.0
HKD3_k127_575098_4 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 389.0
HKD3_k127_575098_5 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 368.0
HKD3_k127_575098_6 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 316.0
HKD3_k127_575098_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 310.0
HKD3_k127_575098_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 308.0
HKD3_k127_575098_9 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000003553 179.0
HKD3_k127_5757192_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 595.0
HKD3_k127_5757192_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 379.0
HKD3_k127_5757192_2 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000000000000000000000006379 139.0
HKD3_k127_5757192_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000001162 104.0
HKD3_k127_5757192_4 phosphorelay signal transduction system - - - 0.00000000000000000001644 95.0
HKD3_k127_5762610_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1149.0
HKD3_k127_5762610_1 Periplasmic binding protein domain K10439 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 323.0
HKD3_k127_5762610_2 Spore maturation protein K06373 - - 0.0000000000000000000000000000000000000000000000000000000000005377 218.0
HKD3_k127_5762610_3 PFAM nucleoside recognition domain protein K06374 - - 0.00000000000000000000000000000000000000000000000000000001862 212.0
HKD3_k127_5762610_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000627 137.0
HKD3_k127_5762610_5 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000006735 99.0
HKD3_k127_5787875_0 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000001332 174.0
HKD3_k127_5787875_1 peptidyl-tyrosine sulfation - - - 0.000000000008842 79.0
HKD3_k127_5787875_2 general secretion pathway protein D K02453 - - 0.0000001792 64.0
HKD3_k127_5787875_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000002264 57.0
HKD3_k127_5787875_4 Dystroglycan-type cadherin-like domains. - - - 0.0000008992 61.0
HKD3_k127_5787875_5 Anti-sigma-K factor rskA - - - 0.000009677 56.0
HKD3_k127_588581_0 amine dehydrogenase activity K14647,K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000002147 243.0
HKD3_k127_588581_1 chlorophyll binding - - - 0.00000000000001631 87.0
HKD3_k127_5934568_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 331.0
HKD3_k127_5934568_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000004466 141.0
HKD3_k127_5934568_2 Beta-lactamase - - - 0.0000000000000000000000000000927 128.0
HKD3_k127_600338_0 Pfam Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004703 508.0
HKD3_k127_600338_1 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005318 406.0
HKD3_k127_600338_2 Belongs to the UPF0597 family - - - 0.000000000000000000000000000000000000000000000000000000000000000199 236.0
HKD3_k127_600338_3 Metal-dependent hydrolase, beta-lactamase superfamily II K06897 - 2.5.1.105 0.000000000000000000000000000000001826 135.0
HKD3_k127_600338_4 PFAM Transcriptional regulator - - - 0.00000000000000000000000000001864 127.0
HKD3_k127_600338_5 subunit of a heme lyase K02200 - - 0.00000000000003113 79.0
HKD3_k127_6044176_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.059e-301 944.0
HKD3_k127_6044176_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 401.0
HKD3_k127_6045950_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 8.988e-198 640.0
HKD3_k127_6045950_1 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.0000000000000000000000000000001784 127.0
HKD3_k127_6045950_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000001856 106.0
HKD3_k127_6045950_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0002794 47.0
HKD3_k127_6058640_0 ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 615.0
HKD3_k127_6058640_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 563.0
HKD3_k127_6058640_10 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 315.0
HKD3_k127_6058640_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 295.0
HKD3_k127_6058640_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 297.0
HKD3_k127_6058640_13 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005055 283.0
HKD3_k127_6058640_14 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006198 276.0
HKD3_k127_6058640_15 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009892 272.0
HKD3_k127_6058640_16 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000002875 259.0
HKD3_k127_6058640_17 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000122 248.0
HKD3_k127_6058640_18 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000006473 180.0
HKD3_k127_6058640_19 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000001208 186.0
HKD3_k127_6058640_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 522.0
HKD3_k127_6058640_20 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000002062 160.0
HKD3_k127_6058640_21 PFAM Alcohol dehydrogenase zinc-binding domain protein K19956 - - 0.0000000000000000000000000000000000001566 157.0
HKD3_k127_6058640_22 GyrI-like small molecule binding domain - - - 0.000000000000000000000000000000009558 133.0
HKD3_k127_6058640_24 Cytidylate kinase-like family - - - 0.00000000000000001486 92.0
HKD3_k127_6058640_25 Domain of unknown function (DUF1844) - - - 0.00000000000000003192 87.0
HKD3_k127_6058640_26 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000005178 70.0
HKD3_k127_6058640_27 shape-determining protein MreD K03571 - - 0.000002759 55.0
HKD3_k127_6058640_28 His Kinase A (phosphoacceptor) domain - - - 0.0000186 52.0
HKD3_k127_6058640_29 Resolvase - - - 0.0006651 43.0
HKD3_k127_6058640_3 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 525.0
HKD3_k127_6058640_4 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 486.0
HKD3_k127_6058640_5 peptidase dimerisation domain protein K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 437.0
HKD3_k127_6058640_6 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 435.0
HKD3_k127_6058640_7 mannitol metabolic process K00009 - 1.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 424.0
HKD3_k127_6058640_8 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 367.0
HKD3_k127_6058640_9 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 332.0
HKD3_k127_6059137_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009482 575.0
HKD3_k127_6059137_1 7TM-HD extracellular K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 411.0
HKD3_k127_6059137_10 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000212 223.0
HKD3_k127_6059137_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000215 191.0
HKD3_k127_6059137_12 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000007076 168.0
HKD3_k127_6059137_13 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000003495 147.0
HKD3_k127_6059137_14 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000005693 145.0
HKD3_k127_6059137_15 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000002626 103.0
HKD3_k127_6059137_16 Pilus assembly protein, PilO K02664 - - 0.000000000000000000579 95.0
HKD3_k127_6059137_17 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000118 84.0
HKD3_k127_6059137_18 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000003879 82.0
HKD3_k127_6059137_2 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 336.0
HKD3_k127_6059137_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 332.0
HKD3_k127_6059137_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 318.0
HKD3_k127_6059137_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 323.0
HKD3_k127_6059137_6 Secretin and TonB N terminus short domain K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 326.0
HKD3_k127_6059137_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008755 252.0
HKD3_k127_6059137_8 SNARE associated Golgi protein K03975,K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000007449 225.0
HKD3_k127_6059137_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000004878 214.0
HKD3_k127_6061772_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 360.0
HKD3_k127_6061772_1 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 319.0
HKD3_k127_6061772_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000007673 222.0
HKD3_k127_6061772_3 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000001436 53.0
HKD3_k127_6063689_0 Beta galactosidase small chain K01190 - 3.2.1.23 0.0 1322.0
HKD3_k127_6063689_1 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 635.0
HKD3_k127_6063689_2 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 422.0
HKD3_k127_6063689_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 367.0
HKD3_k127_6063689_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008754 271.0
HKD3_k127_6063689_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003827 257.0
HKD3_k127_6063689_6 Tetratricopeptide repeat - - - 0.0002889 53.0
HKD3_k127_6072335_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006004,GO:0008150,GO:0008152,GO:0008736,GO:0008790,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0042802,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0046372,GO:0071704,GO:1901575 5.3.1.25,5.3.1.3 7.179e-253 791.0
HKD3_k127_6072335_1 Fumarate hydratase (Fumerase) K01676 - 4.2.1.2 4.482e-227 717.0
HKD3_k127_6072335_10 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000001975 217.0
HKD3_k127_6072335_11 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.0000000000000000000000000000000000000000000000000000000682 205.0
HKD3_k127_6072335_12 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000002508 196.0
HKD3_k127_6072335_13 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000000000213 192.0
HKD3_k127_6072335_14 - - - - 0.000000000000000000000000000000000000005388 164.0
HKD3_k127_6072335_15 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000917 118.0
HKD3_k127_6072335_16 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000143 104.0
HKD3_k127_6072335_17 Bacterial PH domain K08981 - - 0.00000000000001085 81.0
HKD3_k127_6072335_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000005706 67.0
HKD3_k127_6072335_2 xylulokinase activity K00848,K00851,K00854 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0005996,GO:0006793,GO:0006796,GO:0008144,GO:0008150,GO:0008152,GO:0008993,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0019200,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046835,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901575 2.7.1.12,2.7.1.17,2.7.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009988 547.0
HKD3_k127_6072335_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 492.0
HKD3_k127_6072335_4 Molybdate transporter of MFS superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 410.0
HKD3_k127_6072335_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 397.0
HKD3_k127_6072335_6 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 361.0
HKD3_k127_6072335_7 PFAM RhaT l-rhamnose-proton symport 2 K02856 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 336.0
HKD3_k127_6072335_8 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006448 292.0
HKD3_k127_6072335_9 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000004402 260.0
HKD3_k127_6072874_0 Protein of unknown function (DUF2961) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 591.0
HKD3_k127_6072874_1 Phosphate acyltransferases K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 436.0
HKD3_k127_6072874_2 Integral membrane protein TerC family K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 345.0
HKD3_k127_6072874_3 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 313.0
HKD3_k127_6072874_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000001383 156.0
HKD3_k127_6072874_5 Participates in transcription elongation, termination and antitermination K02601,K05785 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000001195 158.0
HKD3_k127_6073880_0 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 388.0
HKD3_k127_6073880_1 and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 370.0
HKD3_k127_6073880_2 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 314.0
HKD3_k127_6073880_3 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 294.0
HKD3_k127_6073880_4 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000003145 167.0
HKD3_k127_6077578_0 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 311.0
HKD3_k127_6077578_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000123 285.0
HKD3_k127_6077578_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000003743 73.0
HKD3_k127_6077578_3 Pyruvate phosphate dikinase - - - 0.00001486 51.0
HKD3_k127_6079314_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001228 271.0
HKD3_k127_6079314_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000002983 182.0
HKD3_k127_6079314_2 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04751,K04752 - - 0.000000000000000000000000000000000000006071 151.0
HKD3_k127_6079314_3 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 0.00000000000000000000000000000000000003307 145.0
HKD3_k127_6079673_0 AcrB/AcrD/AcrF family - - - 1.651e-313 989.0
HKD3_k127_6086237_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1143.0
HKD3_k127_6086237_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1022.0
HKD3_k127_6086237_2 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 334.0
HKD3_k127_6086237_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 312.0
HKD3_k127_6086237_4 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000414 207.0
HKD3_k127_6086237_5 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000001483 174.0
HKD3_k127_6086237_6 integral membrane protein - - - 0.0000000000000000000000000000000000002933 150.0
HKD3_k127_6086237_7 TIGRFAM type IV pilus biogenesis stability protein PilW K02656 - - 0.0004643 48.0
HKD3_k127_6088558_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 426.0
HKD3_k127_6088558_1 Catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.00000000000000000000000000000000000000000000000000000002702 203.0
HKD3_k127_6088558_2 Belongs to the pseudouridine synthase RsuA family K06178 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.22 0.0000000000000000000000000000000000000000007132 164.0
HKD3_k127_6100526_0 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 418.0
HKD3_k127_6100526_1 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000005673 194.0
HKD3_k127_6100526_2 BON domain - - - 0.000000000000000000000000000000000000000000000000006119 187.0
HKD3_k127_6100526_3 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - 0.000000000000000001844 87.0
HKD3_k127_611170_0 PFAM Cytochrome c assembly protein K02198 - - 7.841e-200 643.0
HKD3_k127_611170_1 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000002332 110.0
HKD3_k127_611170_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000006899 112.0
HKD3_k127_611170_3 ABC transporter K01990 - - 0.000000000000000000003419 99.0
HKD3_k127_611170_4 - - - - 0.00000000000000005023 94.0
HKD3_k127_611170_5 subunit of a heme lyase K02200 - - 0.0000000000503 70.0
HKD3_k127_611170_6 - - - - 0.000000513 59.0
HKD3_k127_611196_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000002208 226.0
HKD3_k127_611196_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000006099 179.0
HKD3_k127_6122982_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 482.0
HKD3_k127_6122982_1 DJ-1/PfpI family K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 317.0
HKD3_k127_6122982_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000002421 171.0
HKD3_k127_6122982_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000001179 149.0
HKD3_k127_6122982_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000006287 98.0
HKD3_k127_6135642_0 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 380.0
HKD3_k127_6135642_1 flagellar hook-associated protein K02396 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005711 263.0
HKD3_k127_6135642_10 Anti-sigma-28 factor, FlgM K02398 - - 0.00001458 51.0
HKD3_k127_6135642_2 Rod binding protein K21471 - - 0.0000000000000000000000000000000000007189 150.0
HKD3_k127_6135642_3 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.00000000000000000000000004308 113.0
HKD3_k127_6135642_4 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000003604 120.0
HKD3_k127_6135642_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000008458 104.0
HKD3_k127_6135642_6 flagellar protein FliS K02422 - - 0.0000000000000000002057 94.0
HKD3_k127_6135642_7 Belongs to the bacterial flagellin family K02397 - - 0.000000000000000001191 96.0
HKD3_k127_6135642_8 Carbon storage regulator homolog K03563 - - 0.0000000000000001038 81.0
HKD3_k127_6144797_0 beta-galactosidase activity K12308 - 3.2.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 374.0
HKD3_k127_6144797_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000001042 188.0
HKD3_k127_6144797_2 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000000003936 156.0
HKD3_k127_6159761_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1041.0
HKD3_k127_6159761_1 histidine kinase A domain protein - - - 2.266e-209 685.0
HKD3_k127_6159761_10 von willebrand factor type a K07114 - - 0.000003031 58.0
HKD3_k127_6159761_2 glycerol channel activity K09876,K09877,K09886,K10404 GO:0002376,GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006833,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008643,GO:0009605,GO:0009607,GO:0009617,GO:0015250,GO:0015267,GO:0015318,GO:0015791,GO:0015793,GO:0015850,GO:0016020,GO:0016323,GO:0022803,GO:0022838,GO:0022857,GO:0042044,GO:0042742,GO:0043207,GO:0044425,GO:0044459,GO:0044464,GO:0045087,GO:0050829,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055085,GO:0071702,GO:0071944,GO:0098542,GO:0098590 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003557 273.0
HKD3_k127_6159761_3 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000006185 189.0
HKD3_k127_6159761_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000017 161.0
HKD3_k127_6159761_5 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000001966 129.0
HKD3_k127_6159761_6 diguanylate cyclase - - - 0.000000000000000000000000004225 114.0
HKD3_k127_6159761_7 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000003279 94.0
HKD3_k127_6159761_8 Outer membrane efflux protein - - - 0.00000000000000001313 98.0
HKD3_k127_6159761_9 PFAM PspA IM30 family K03969 - - 0.0000002311 61.0
HKD3_k127_6163963_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 327.0
HKD3_k127_6163963_1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain K01683 - 4.2.1.5 0.000000000000000000000000000000000000000006371 168.0
HKD3_k127_6166329_0 Domain of unknown function (DUF1998) K06877 - - 7.528e-300 939.0
HKD3_k127_6166329_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 6.081e-197 643.0
HKD3_k127_6166329_10 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001671 277.0
HKD3_k127_6166329_11 transporter - - - 0.00000000000000000000000000000000000000000000000000000003038 210.0
HKD3_k127_6166329_12 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000007879 205.0
HKD3_k127_6166329_13 Phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000003974 105.0
HKD3_k127_6166329_14 PFAM CHAD domain containing protein - - - 0.000000000006943 77.0
HKD3_k127_6166329_15 Phosphorylase superfamily - - - 0.0000001198 62.0
HKD3_k127_6166329_2 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 595.0
HKD3_k127_6166329_3 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 455.0
HKD3_k127_6166329_4 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009964 409.0
HKD3_k127_6166329_5 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 393.0
HKD3_k127_6166329_6 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 380.0
HKD3_k127_6166329_7 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008656 388.0
HKD3_k127_6166329_8 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 333.0
HKD3_k127_6166329_9 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 305.0
HKD3_k127_6169222_0 N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) K16213 - 5.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 441.0
HKD3_k127_6169222_1 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000003095 240.0
HKD3_k127_6169222_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000003553 209.0
HKD3_k127_6169222_3 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000002285 175.0
HKD3_k127_6169222_4 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000004074 149.0
HKD3_k127_6169222_5 Regulatory protein, FmdB family - - - 0.00000001501 58.0
HKD3_k127_6169222_6 Putative zinc-finger - - - 0.0000003592 53.0
HKD3_k127_6172326_0 cellulose binding - - - 0.0 1103.0
HKD3_k127_6172326_1 L-lactate permease K03303 - - 1.797e-208 668.0
HKD3_k127_6172326_2 Belongs to the glycosyl hydrolase 3 family K05349,K17641 - 3.2.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 471.0
HKD3_k127_6172326_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 339.0
HKD3_k127_6172326_4 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 329.0
HKD3_k127_6172326_5 heme binding K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000001336 203.0
HKD3_k127_6181548_0 Carboxypeptidase regulatory-like domain - - - 0.0 1566.0
HKD3_k127_6181548_1 ASPIC and UnbV - - - 2.03e-201 642.0
HKD3_k127_6181548_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000004218 133.0
HKD3_k127_6181548_12 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000004457 106.0
HKD3_k127_6181548_13 Endoribonuclease L-PSP - - - 0.0000000000000000215 94.0
HKD3_k127_6181548_14 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000005174 78.0
HKD3_k127_6181548_2 Iodothyronine deiodinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 499.0
HKD3_k127_6181548_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 451.0
HKD3_k127_6181548_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 430.0
HKD3_k127_6181548_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 350.0
HKD3_k127_6181548_6 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 326.0
HKD3_k127_6181548_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 307.0
HKD3_k127_6181548_8 FAD dependent oxidoreductase K00109 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000007947 241.0
HKD3_k127_6181548_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000002262 197.0
HKD3_k127_6182058_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1122.0
HKD3_k127_6182058_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 586.0
HKD3_k127_6182058_2 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 359.0
HKD3_k127_6182058_3 Protein of unknown function (DUF512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009505 342.0
HKD3_k127_6182058_4 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003713 247.0
HKD3_k127_6182058_5 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000408 233.0
HKD3_k127_6182058_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000002292 206.0
HKD3_k127_6182058_7 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000004461 141.0
HKD3_k127_6196213_0 Large extracellular alpha-helical protein - - - 0.0 2165.0
HKD3_k127_6196213_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1270.0
HKD3_k127_6196213_10 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000001092 226.0
HKD3_k127_6196213_11 NUDIX domain - - - 0.0000000000000000000000000000000000001738 148.0
HKD3_k127_6196213_12 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000000000000000000000000007296 139.0
HKD3_k127_6196213_13 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000005022 91.0
HKD3_k127_6196213_14 Integral membrane protein TerC family K05794 - - 0.000000000000004123 78.0
HKD3_k127_6196213_15 Mycolic acid cyclopropane synthetase - - - 0.00000000000001697 81.0
HKD3_k127_6196213_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.111e-308 963.0
HKD3_k127_6196213_3 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 8.482e-198 624.0
HKD3_k127_6196213_4 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 572.0
HKD3_k127_6196213_5 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 346.0
HKD3_k127_6196213_6 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 327.0
HKD3_k127_6196213_7 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 310.0
HKD3_k127_6196213_8 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002141 281.0
HKD3_k127_6196213_9 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004261 248.0
HKD3_k127_6202587_0 GMC oxidoreductase - - - 9.796e-243 761.0
HKD3_k127_6202587_1 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.146e-202 641.0
HKD3_k127_6202587_2 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 334.0
HKD3_k127_6202587_3 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 302.0
HKD3_k127_6202587_4 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 291.0
HKD3_k127_6202587_5 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000003862 214.0
HKD3_k127_6202587_6 protein conserved in bacteria K16168 - - 0.000000000000000000000000000000000000000000000001492 183.0
HKD3_k127_6204232_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 4.043e-219 686.0
HKD3_k127_6204232_1 Pfam:DUF303 K05970 - 3.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 500.0
HKD3_k127_6204232_2 PFAM Pentapeptide repeats (8 copies) - - - 0.000000000000000000000000000009257 129.0
HKD3_k127_6204232_3 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000003126 108.0
HKD3_k127_6217548_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1147.0
HKD3_k127_6217548_1 FMN binding - - - 5.13e-242 757.0
HKD3_k127_6217548_2 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000657 279.0
HKD3_k127_6235862_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.086e-251 786.0
HKD3_k127_6235862_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 565.0
HKD3_k127_6235862_2 - - - - 0.0000000000007521 78.0
HKD3_k127_6235862_3 membrane K11622 - - 0.0000000003441 64.0
HKD3_k127_6235862_4 Peptidase family S58 K01266 - 3.4.11.19 0.000000001678 63.0
HKD3_k127_6251701_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 2.783e-257 808.0
HKD3_k127_6251701_1 Domain of unknown function (DUF1846) - - - 8.432e-254 790.0
HKD3_k127_6251701_2 Glycosyl hydrolase family 20, domain 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 495.0
HKD3_k127_6251701_3 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 439.0
HKD3_k127_6251701_4 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000004742 168.0
HKD3_k127_6263446_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 585.0
HKD3_k127_6263446_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000001125 239.0
HKD3_k127_6263446_2 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000004974 182.0
HKD3_k127_6263446_3 Fibronectin type 3 domain - - - 0.000007941 57.0
HKD3_k127_6267245_0 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 3.56e-322 1015.0
HKD3_k127_6267245_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 381.0
HKD3_k127_6267245_2 PFAM Response regulator receiver domain K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 370.0
HKD3_k127_6267245_3 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007662 287.0
HKD3_k127_6267245_4 impB/mucB/samB family K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000002805 247.0
HKD3_k127_6267245_5 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000005085 177.0
HKD3_k127_6267245_7 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000203 115.0
HKD3_k127_6267245_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000001343 88.0
HKD3_k127_6283740_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.742e-318 982.0
HKD3_k127_6283740_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 587.0
HKD3_k127_6283740_10 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 306.0
HKD3_k127_6283740_11 ribosylpyrimidine nucleosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 292.0
HKD3_k127_6283740_12 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002465 295.0
HKD3_k127_6283740_13 PFAM dihydropteroate synthase, DHPS K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000002148 267.0
HKD3_k127_6283740_14 PFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000001099 253.0
HKD3_k127_6283740_16 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000007995 239.0
HKD3_k127_6283740_18 Histidine kinase K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000004397 192.0
HKD3_k127_6283740_19 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000005125 179.0
HKD3_k127_6283740_2 Bacteriocin K20344 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 529.0
HKD3_k127_6283740_20 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000005993 175.0
HKD3_k127_6283740_21 PFAM Cyclic nucleotide-binding domain - - - 0.0000000000000000000000000000000000002838 146.0
HKD3_k127_6283740_22 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000001094 141.0
HKD3_k127_6283740_23 cheY-homologous receiver domain - - - 0.0000000000000000000000000000001698 128.0
HKD3_k127_6283740_24 - - - - 0.0000000000000000000000000007335 119.0
HKD3_k127_6283740_25 - - - - 0.00000000000001749 75.0
HKD3_k127_6283740_26 VanZ like family - - - 0.00000000000009793 76.0
HKD3_k127_6283740_27 regulation of bacterial-type flagellum-dependent cell motility by regulation of motor speed - - - 0.00000000001572 74.0
HKD3_k127_6283740_28 VanZ like family - - - 0.0000003119 62.0
HKD3_k127_6283740_3 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 492.0
HKD3_k127_6283740_4 Carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 491.0
HKD3_k127_6283740_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 422.0
HKD3_k127_6283740_6 Major Facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 395.0
HKD3_k127_6283740_7 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 377.0
HKD3_k127_6283740_8 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004861 343.0
HKD3_k127_6283740_9 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 321.0
HKD3_k127_6288024_0 mandelate racemase muconate lactonizing K08323 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0008150,GO:0008152,GO:0008927,GO:0009056,GO:0016052,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0044238,GO:0046872,GO:0047929,GO:0071704,GO:1901575 4.2.1.8 3.067e-202 642.0
HKD3_k127_6288024_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.895e-198 629.0
HKD3_k127_6288024_2 Heparinase II/III-like protein - - - 1.211e-195 626.0
HKD3_k127_6288024_3 2-epimerase K16213 - 5.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 466.0
HKD3_k127_6288024_4 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 393.0
HKD3_k127_6288024_5 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K07516 - 1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000947 283.0
HKD3_k127_6288024_6 Belongs to the ompA family - - - 0.00000000000000000000003574 110.0
HKD3_k127_6288024_7 Virulence factor BrkB K07058 - - 0.0000000715 55.0
HKD3_k127_6304349_0 Magnesium transport protein CorA K03284 - - 5.439e-206 655.0
HKD3_k127_6304349_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001898 250.0
HKD3_k127_6304349_2 protein with SCP PR1 domains - - - 0.00000000000002943 83.0
HKD3_k127_6305002_0 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 464.0
HKD3_k127_6305002_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
HKD3_k127_6305002_2 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 298.0
HKD3_k127_6305002_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003966 284.0
HKD3_k127_6305002_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004254 282.0
HKD3_k127_6305002_5 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000006614 190.0
HKD3_k127_6305002_6 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000005765 129.0
HKD3_k127_6305002_7 efflux transmembrane transporter activity - - - 0.00000000000000000000000000004209 123.0
HKD3_k127_6305002_8 FtsX-like permease family - - - 0.0000000000000000000001346 105.0
HKD3_k127_6305002_9 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.0000000002066 65.0
HKD3_k127_6349616_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 528.0
HKD3_k127_6349616_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 504.0
HKD3_k127_6349616_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 493.0
HKD3_k127_6349616_3 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 431.0
HKD3_k127_6349616_4 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 431.0
HKD3_k127_6349616_5 Conserved protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 361.0
HKD3_k127_6349616_6 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008421 357.0
HKD3_k127_6349616_7 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 327.0
HKD3_k127_6349616_8 belongs to the nudix hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
HKD3_k127_6349616_9 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000001509 228.0
HKD3_k127_6352943_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1269.0
HKD3_k127_6352943_1 Belongs to the universal stress protein A family - - - 0.0000000000000000000006628 111.0
HKD3_k127_6352943_2 Protein of unknown function (DUF2892) - - - 0.0000000000000000001091 93.0
HKD3_k127_6352943_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00001261 49.0
HKD3_k127_6391431_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 346.0
HKD3_k127_6391431_1 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 325.0
HKD3_k127_6391431_2 - - - - 0.00000000000000000000000000000000000000000000000000003691 200.0
HKD3_k127_6391431_3 Involved in the tonB-independent uptake of proteins K03641 - - 0.00002085 49.0
HKD3_k127_6391431_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.0001077 53.0
HKD3_k127_6416087_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 469.0
HKD3_k127_6416087_1 TIGRFAM Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 297.0
HKD3_k127_6416087_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 291.0
HKD3_k127_6416087_3 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000001972 256.0
HKD3_k127_6416087_4 phosphoprotein phosphatase activity K14680 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000005991 216.0
HKD3_k127_6416087_5 translation release factor activity K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000002274 107.0
HKD3_k127_6416087_6 SMART phosphoesterase PHP domain protein - - - 0.000000000003723 76.0
HKD3_k127_6416087_7 Saccharopine dehydrogenase C-terminal domain - - - 0.000001175 55.0
HKD3_k127_6455402_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 627.0
HKD3_k127_6455402_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.0000000000000000000000000000000963 128.0
HKD3_k127_6466049_0 2-keto-3-deoxy-L-rhamnonate aldolase activity K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 300.0
HKD3_k127_6466049_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000003472 76.0
HKD3_k127_6491762_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 552.0
HKD3_k127_6491762_1 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 494.0
HKD3_k127_6491762_10 Protein of unknown function (DUF3108) - - - 0.00000000002302 74.0
HKD3_k127_6491762_2 PFAM Cation transporter K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 398.0
HKD3_k127_6491762_3 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 360.0
HKD3_k127_6491762_4 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 319.0
HKD3_k127_6491762_5 PFAM TrkA-N domain K03499 - - 0.000000000000000000000000000000000000000000000000000001787 199.0
HKD3_k127_6491762_6 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000001446 153.0
HKD3_k127_6491762_7 Glycosyltransferase family 9 (heptosyltransferase) K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000005206 93.0
HKD3_k127_6491762_8 Ribosomal L28 family K02902 - - 0.000000000000000001759 87.0
HKD3_k127_6491762_9 - - - - 0.000000000000001715 83.0
HKD3_k127_6492963_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 595.0
HKD3_k127_6492963_1 carboxylic acid catabolic process K01684 - 4.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 561.0
HKD3_k127_6492963_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 456.0
HKD3_k127_6492963_3 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007088 383.0
HKD3_k127_6492963_4 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000000000000002096 165.0
HKD3_k127_6492963_5 efflux transmembrane transporter activity - - - 0.00000000000000000005329 96.0
HKD3_k127_6492963_6 fatty acid desaturase - - - 0.00000000000104 79.0
HKD3_k127_6528208_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000002897 179.0
HKD3_k127_6528208_1 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000002478 179.0
HKD3_k127_6645561_0 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 357.0
HKD3_k127_6645561_1 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000004953 169.0
HKD3_k127_6645561_2 General secretion pathway protein H K02457 - - 0.00000000006584 70.0
HKD3_k127_6645561_3 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000048 55.0
HKD3_k127_6645561_4 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0001891 53.0
HKD3_k127_6645561_5 type IV pilus modification protein PilV K02458 - - 0.0006945 49.0
HKD3_k127_6653391_0 Belongs to the glycosyl hydrolase 2 family K15855 - 3.2.1.165 0.0 1036.0
HKD3_k127_6653391_1 and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 542.0
HKD3_k127_6653391_2 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose K16212 - 2.4.1.281 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 446.0
HKD3_k127_6653391_3 Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man) K16213 - 5.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 423.0
HKD3_k127_6653391_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.0004131 46.0
HKD3_k127_6672796_0 HELICc2 K03722 - 3.6.4.12 2.092e-203 653.0
HKD3_k127_6672796_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 563.0
HKD3_k127_6672796_2 Responsible for synthesis of pseudouridine from uracil K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000001177 233.0
HKD3_k127_6672796_3 - - - - 0.000000000000000000009749 98.0
HKD3_k127_6672796_4 Ribose/Galactose Isomerase K01808,K01819 - 5.3.1.26,5.3.1.6 0.0000008472 51.0
HKD3_k127_6678880_0 phosphoglucosamine mutase activity K00971,K01840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.13,5.4.2.8 4.387e-234 740.0
HKD3_k127_6678880_1 Major Facilitator Superfamily - - - 1.136e-208 655.0
HKD3_k127_6678880_10 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 318.0
HKD3_k127_6678880_11 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 323.0
HKD3_k127_6678880_12 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 313.0
HKD3_k127_6678880_13 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001079 276.0
HKD3_k127_6678880_14 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase - - - 0.0000000000000000000000000000000002191 145.0
HKD3_k127_6678880_15 amidohydrolase K07045 - - 0.0000000000000000000000001232 117.0
HKD3_k127_6678880_16 Glycosyltransferases involved in cell wall biogenesis-like protein - - - 0.0000000002668 74.0
HKD3_k127_6678880_17 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.0000000006217 67.0
HKD3_k127_6678880_2 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 590.0
HKD3_k127_6678880_3 PFAM Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 445.0
HKD3_k127_6678880_4 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 460.0
HKD3_k127_6678880_5 Dihydrodipicolinate synthase N-acetylneuraminate lyase K01639 - 4.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 392.0
HKD3_k127_6678880_6 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008593 372.0
HKD3_k127_6678880_7 Domain of unknown function (DUF4432) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 363.0
HKD3_k127_6678880_8 TIGRFAM mannose-6-phosphate isomerase, class I K01809 - 5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 357.0
HKD3_k127_6678880_9 Xylose isomerase domain protein TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 343.0
HKD3_k127_668141_0 GatB/GatE catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 443.0
HKD3_k127_668141_1 creatininase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 358.0
HKD3_k127_668141_2 Asparaginase K01424 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000004093 231.0
HKD3_k127_668141_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00002997 47.0
HKD3_k127_6777514_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001131 280.0
HKD3_k127_6777514_1 - - - - 0.000000000000000000000000000000003092 132.0
HKD3_k127_6790317_0 mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 323.0
HKD3_k127_6790317_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000002721 91.0
HKD3_k127_6818018_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 452.0
HKD3_k127_686035_0 ErfK YbiS YcfS YnhG family protein K21470 - - 1.748e-210 667.0
HKD3_k127_686035_1 cell wall glycoprotein biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 603.0
HKD3_k127_686035_10 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000007127 185.0
HKD3_k127_686035_11 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000294 176.0
HKD3_k127_686035_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000001553 146.0
HKD3_k127_686035_13 - - - - 0.0000000000000000000000001867 113.0
HKD3_k127_686035_14 - - - - 0.000000000000000000693 96.0
HKD3_k127_686035_16 Beta-lactamase - - - 0.00000000001201 69.0
HKD3_k127_686035_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 552.0
HKD3_k127_686035_3 PFAM Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 441.0
HKD3_k127_686035_4 dehydrogenases and related proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 412.0
HKD3_k127_686035_5 AP endonuclease family 2 C terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 374.0
HKD3_k127_686035_6 Bacterial regulatory protein, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 381.0
HKD3_k127_686035_7 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 297.0
HKD3_k127_686035_8 acetylesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005918 297.0
HKD3_k127_686035_9 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005547 250.0
HKD3_k127_68674_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 585.0
HKD3_k127_68674_1 oligopeptide transport K03305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 526.0
HKD3_k127_68674_3 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 302.0
HKD3_k127_68674_4 alpha beta - - - 0.0000000000000000000000000000000000000727 143.0
HKD3_k127_68674_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000002447 130.0
HKD3_k127_68674_6 PFAM Stress responsive A B Barrel Domain - - - 0.0000000000000000000000000000007082 126.0
HKD3_k127_68674_7 Cold shock protein domain K03704 - - 0.00000000000000000000000000001736 119.0
HKD3_k127_68674_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000002726 108.0
HKD3_k127_68674_9 Hexapeptide repeat of succinyl-transferase - - - 0.0000358 56.0
HKD3_k127_6875073_0 L-rhamnose isomerase K01813 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.14 1.224e-197 623.0
HKD3_k127_6875073_1 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008945 504.0
HKD3_k127_687765_0 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 389.0
HKD3_k127_687765_1 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000001294 157.0
HKD3_k127_687765_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000001713 74.0
HKD3_k127_6891976_0 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 494.0
HKD3_k127_6891976_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007037 280.0
HKD3_k127_6891976_2 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000003333 250.0
HKD3_k127_6891976_3 Flavin containing amine oxidoreductase K06954 - - 0.000000000000472 69.0
HKD3_k127_6954537_0 AAA domain - - - 5.159e-271 856.0
HKD3_k127_6954537_1 PFAM S23 ribosomal protein - - - 0.00000000000000000000000000001965 121.0
HKD3_k127_6954537_2 TPR repeat-containing protein - - - 0.0000000000000002306 93.0
HKD3_k127_6954537_3 peptidyl-tyrosine sulfation - - - 0.000000000003589 78.0
HKD3_k127_6954537_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00004587 46.0
HKD3_k127_7000069_0 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 3.62e-209 663.0
HKD3_k127_7000069_1 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 361.0
HKD3_k127_7000069_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000001478 267.0
HKD3_k127_7000069_3 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000001133 222.0
HKD3_k127_701165_0 PFAM von Willebrand factor type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008785 228.0
HKD3_k127_701165_1 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000005731 240.0
HKD3_k127_701165_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000001026 158.0
HKD3_k127_701165_3 DinB family - - - 0.00000000000000000000000000000000000000001287 159.0
HKD3_k127_701165_4 Serine/threonine phosphatases, family 2C, catalytic domain - - - 0.000000000000000005598 94.0
HKD3_k127_701165_5 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.00000000000003009 77.0
HKD3_k127_701165_6 - - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.000000191 59.0
HKD3_k127_701165_7 - - - - 0.000001127 58.0
HKD3_k127_701165_8 SpoVT / AbrB like domain - - - 0.00005108 51.0
HKD3_k127_7014343_0 phosphorelay signal transduction system K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 486.0
HKD3_k127_7014343_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000001616 203.0
HKD3_k127_7014343_2 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000005998 147.0
HKD3_k127_7014343_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000007486 135.0
HKD3_k127_7014343_4 - - - - 0.0000000000826 70.0
HKD3_k127_7058683_0 PFAM Xylose isomerase domain protein TIM barrel K01805 - 5.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 560.0
HKD3_k127_7058683_1 PFAM peptidase M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 333.0
HKD3_k127_7058683_2 tRNA m6t6A37 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003191 220.0
HKD3_k127_7058683_3 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000000000000000000000000000167 220.0
HKD3_k127_7058683_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000574 115.0
HKD3_k127_7058683_5 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000002124 57.0
HKD3_k127_712545_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 325.0
HKD3_k127_712545_1 Major Facilitator Superfamily K02445,K07783 - - 0.000000000000000000000000000000000000000000000002487 179.0
HKD3_k127_712545_2 - - - - 0.0000000000000003553 81.0
HKD3_k127_712545_3 Zinc-binding dehydrogenase K12957 - - 0.000000000011 67.0
HKD3_k127_7193410_0 Aldehyde dehydrogenase family K00140,K22187 - 1.2.1.18,1.2.1.27 9.948e-218 689.0
HKD3_k127_7193410_1 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 323.0
HKD3_k127_7193410_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000008739 235.0
HKD3_k127_7193410_3 cellulose binding K08604,K12132 - 2.7.11.1,3.4.24.25 0.00000000007119 74.0
HKD3_k127_7200394_0 NADP-dependent oxidoreductase K00001,K07119 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001314 239.0
HKD3_k127_7200394_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000002084 143.0
HKD3_k127_7203952_0 Tricorn protease PDZ domain K08676 - - 0.0 1266.0
HKD3_k127_7203952_1 Sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 512.0
HKD3_k127_7203952_2 PFAM Peptidase family M3 K01284 - 3.4.15.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 320.0
HKD3_k127_7203952_3 mannose-1-phosphate guanylyltransferase activity K00971,K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000005735 171.0
HKD3_k127_7203952_4 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000005743 164.0
HKD3_k127_7212901_0 Carbohydrate phosphorylase K00688,K00691 - 2.4.1.1,2.4.1.8 0.0 1026.0
HKD3_k127_7212901_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003604 530.0
HKD3_k127_7212901_2 radical SAM domain protein K15045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 508.0
HKD3_k127_7212901_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 420.0
HKD3_k127_7212901_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 417.0
HKD3_k127_7250379_0 Protein of unknown function (DUF3750) - - - 0.0000000000000000000004725 98.0
HKD3_k127_7250379_1 - - - - 0.0000000000000000002054 100.0
HKD3_k127_7250379_2 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000959 47.0
HKD3_k127_7253479_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 436.0
HKD3_k127_7253479_1 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002367 272.0
HKD3_k127_7253479_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000009087 239.0
HKD3_k127_7253479_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000002546 195.0
HKD3_k127_7253479_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000005922 185.0
HKD3_k127_7253479_5 MlaD protein K02067 - - 0.000000000000000000000000000000000000000002019 171.0
HKD3_k127_7253479_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000001888 100.0
HKD3_k127_725816_0 Domain of unknown function (DUF4091) - - - 8.744e-226 713.0
HKD3_k127_725816_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 424.0
HKD3_k127_725816_2 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 358.0
HKD3_k127_725816_3 TRANSCRIPTIONal - - - 0.000000000000000000000000000000000000000000000000000000000008312 212.0
HKD3_k127_725816_4 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.00000000000000000000000000000000000000000000000000000000001395 211.0
HKD3_k127_725816_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00188 - 1.2.7.7 0.0000000000000002952 81.0
HKD3_k127_725816_6 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000001544 79.0
HKD3_k127_725816_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.00000221 49.0
HKD3_k127_7260106_0 Protein of unknown function (DUF3419) K13622 - - 0.000000000000000000000000000000000000000000000000000000000000007806 232.0
HKD3_k127_7260106_1 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000127 220.0
HKD3_k127_7260106_2 Amidohydrolase family - - - 0.00000000000000000000000000000002139 127.0
HKD3_k127_7260106_3 PFAM Diacylglycerol kinase catalytic - - - 0.0000000000000000006028 96.0
HKD3_k127_7260106_4 Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP K01004 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24 0.0000000000002929 79.0
HKD3_k127_7287348_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007567 289.0
HKD3_k127_7287348_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000003498 182.0
HKD3_k127_7294557_0 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006587 341.0
HKD3_k127_7294557_1 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 285.0
HKD3_k127_7294557_2 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000005485 230.0
HKD3_k127_729513_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 444.0
HKD3_k127_729513_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 345.0
HKD3_k127_729513_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000472 281.0
HKD3_k127_729513_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000002595 254.0
HKD3_k127_729513_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000007233 203.0
HKD3_k127_729513_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000001106 182.0
HKD3_k127_729513_6 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000009982 169.0
HKD3_k127_7295766_0 peptidyl-tyrosine sulfation - - - 3.808e-290 900.0
HKD3_k127_7295766_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000001242 223.0
HKD3_k127_7295766_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001041 143.0
HKD3_k127_7300937_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 569.0
HKD3_k127_7300937_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 404.0
HKD3_k127_7300937_2 SWIM zinc finger - - - 0.0000000006493 63.0
HKD3_k127_7300937_3 PIN domain - - - 0.00000005421 60.0
HKD3_k127_7302622_1 hydrolase activity, hydrolyzing O-glycosyl compounds K12373 - 3.2.1.52 0.0000001281 63.0
HKD3_k127_7308804_0 Alpha/beta hydrolase family K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 534.0
HKD3_k127_7308804_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 425.0
HKD3_k127_7308804_2 COG COG1073 Hydrolases of the alpha beta superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003199 228.0
HKD3_k127_7308804_3 succinyl-diaminopimelate desuccinylase activity - - - 0.0000000000000000000000000000000000000000000000000000000489 199.0
HKD3_k127_7316195_0 Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 439.0
HKD3_k127_7316195_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000007856 266.0
HKD3_k127_7316195_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000009718 189.0
HKD3_k127_7316195_3 oxidation-reduction process K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000622 172.0
HKD3_k127_7316195_4 Thiol-disulfide isomerase and - - - 0.000000000000000000000000006572 117.0
HKD3_k127_7316195_5 Acetyltransferase (GNAT) domain - - - 0.000006315 55.0
HKD3_k127_7316854_0 LssY C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 565.0
HKD3_k127_7320054_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 489.0
HKD3_k127_7320054_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 413.0
HKD3_k127_7320054_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000002476 117.0
HKD3_k127_7320054_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000002472 113.0
HKD3_k127_7320054_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000005252 109.0
HKD3_k127_7320054_13 Protein of unknown function (DUF503) K09764 - - 0.0000000000000000227 85.0
HKD3_k127_7320054_14 Helix-hairpin-helix motif K02237 - - 0.0000000000000001033 88.0
HKD3_k127_7320054_15 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000649 68.0
HKD3_k127_7320054_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 308.0
HKD3_k127_7320054_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001121 280.0
HKD3_k127_7320054_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000006813 227.0
HKD3_k127_7320054_5 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000005633 190.0
HKD3_k127_7320054_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000416 183.0
HKD3_k127_7320054_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000001395 183.0
HKD3_k127_7320054_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000001591 171.0
HKD3_k127_7320054_9 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000005624 156.0
HKD3_k127_7322979_0 COG3119 Arylsulfatase A K01138 - - 3.987e-211 665.0
HKD3_k127_7322979_1 Sulfate transporter antisigma-factor antagonist STAS - - - 1.751e-195 626.0
HKD3_k127_7322979_10 Capsule biosynthesis CapC K22116 - - 0.0000000000000000001949 93.0
HKD3_k127_7322979_11 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000007771 89.0
HKD3_k127_7322979_2 Melibiase K07407 GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0009056,GO:0015925,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0042802,GO:0042803,GO:0046983,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 388.0
HKD3_k127_7322979_3 Mur ligase middle domain K01317,K01925,K01928,K01932 - 3.4.21.10,6.3.2.13,6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001551 276.0
HKD3_k127_7322979_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005382 258.0
HKD3_k127_7322979_5 Pfam Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004376 248.0
HKD3_k127_7322979_6 Melibiase K07407 GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0009056,GO:0015925,GO:0016137,GO:0016139,GO:0016787,GO:0016798,GO:0042802,GO:0042803,GO:0046983,GO:0071704,GO:1901135,GO:1901136,GO:1901575,GO:1901657,GO:1901658 3.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000872 241.0
HKD3_k127_7322979_7 DoxX - - - 0.00000000000000000000000000000000000000000000000005466 182.0
HKD3_k127_7322979_8 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000003059 144.0
HKD3_k127_7322979_9 Also exhibits in vitro acyl transferase activity, transferring the acyl moiety of short-chain amides to hydroxylamine to form hydroxamates K01455 - 3.5.1.49 0.00000000000000000000000000008084 128.0
HKD3_k127_7336310_0 PFAM Y_Y_Y domain - - - 1.373e-209 700.0
HKD3_k127_7336310_1 Domain of unknown function (DUF4091) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 582.0
HKD3_k127_7336310_2 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 384.0
HKD3_k127_7336310_3 Stage II sporulation K07315 - 3.1.3.3 0.00004567 47.0
HKD3_k127_7341857_0 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 591.0
HKD3_k127_7341857_1 oxidoreductase - - - 0.000000000000003721 81.0
HKD3_k127_7341857_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000089 51.0
HKD3_k127_73425_0 Transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 361.0
HKD3_k127_73425_1 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000002635 189.0
HKD3_k127_7346089_0 efflux transmembrane transporter activity - - - 7.498e-235 747.0
HKD3_k127_7346089_1 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00000000001745 74.0
HKD3_k127_7346089_2 Transcriptional regulatory protein, C terminal - - - 0.0001627 48.0
HKD3_k127_7351235_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007312 605.0
HKD3_k127_7351235_1 integral membrane protein - - - 0.0001564 51.0
HKD3_k127_7353914_0 TIGRFAM The (Largely Gram-negative Bacterial) Hydrophobe Amphiphile Efflux-1 (HAE1) Family K03296,K18138 - - 1.721e-281 876.0
HKD3_k127_7353914_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.000001893 53.0
HKD3_k127_7360745_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004715 533.0
HKD3_k127_7360745_1 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 310.0
HKD3_k127_7360745_2 Periplasmic binding protein domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008265 309.0
HKD3_k127_7360745_3 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 300.0
HKD3_k127_7360745_4 Belongs to the binding-protein-dependent transport system permease family K10440,K17203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001922 278.0
HKD3_k127_7360745_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003064 266.0
HKD3_k127_7360745_6 Belongs to the GTP cyclohydrolase I type 2 NIF3 family K22391 - 3.5.4.16 0.000000000000000000000000000000000000005618 159.0
HKD3_k127_7360745_7 - - - - 0.0000000000000000000000006745 109.0
HKD3_k127_7360745_8 - - - - 0.00000000000000000001086 95.0
HKD3_k127_7360745_9 DinB family - - - 0.0000000002315 70.0
HKD3_k127_7365676_0 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 356.0
HKD3_k127_7365676_1 Cytidylate kinase-like family K00945 - 2.7.4.25 0.00000000000003595 82.0
HKD3_k127_7387611_0 Psort location Cytoplasmic, score K00266 - 1.4.1.13,1.4.1.14 7.515e-198 636.0
HKD3_k127_7387611_1 Alpha-L-fucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 570.0
HKD3_k127_7387611_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002339 271.0
HKD3_k127_7387611_3 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000008604 224.0
HKD3_k127_7387611_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000007685 133.0
HKD3_k127_7387611_5 - - - - 0.00000000000000000000000001667 121.0
HKD3_k127_7387611_6 Domain of unknown function (DUF362) - - - 0.000000000001033 78.0
HKD3_k127_7387611_7 Endonuclease/Exonuclease/phosphatase family - - - 0.0000004289 61.0
HKD3_k127_7394653_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 522.0
HKD3_k127_7394653_1 Phosphoglycerate kinase K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004564 499.0
HKD3_k127_7394653_2 Acetyl-CoA carboxylase, central region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000299 281.0
HKD3_k127_7394653_3 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000000000000009847 220.0
HKD3_k127_7394653_4 Protein of unknown function (DUF1326) - - - 0.00000000000007136 80.0
HKD3_k127_7394653_5 Glycogen debranching enzyme K05988 - 3.2.1.11 0.000006089 53.0
HKD3_k127_7408418_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 8.611e-285 889.0
HKD3_k127_7408418_1 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.099e-278 871.0
HKD3_k127_7408418_10 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000001565 133.0
HKD3_k127_7408418_11 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0010468,GO:0016020,GO:0019222,GO:0030312,GO:0040007,GO:0043388,GO:0044093,GO:0044464,GO:0050789,GO:0051098,GO:0051099,GO:0051101,GO:0060255,GO:0065007,GO:0065009,GO:0071944,GO:2000677,GO:2000679 - 0.0000000000000000444 88.0
HKD3_k127_7408418_12 - - - - 0.00000000000002807 78.0
HKD3_k127_7408418_13 Selenoprotein, putative - - - 0.0000003194 55.0
HKD3_k127_7408418_14 PFAM Tetratricopeptide repeat - - - 0.00008364 53.0
HKD3_k127_7408418_2 peptidyl-tyrosine sulfation - - - 1.392e-259 812.0
HKD3_k127_7408418_3 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 487.0
HKD3_k127_7408418_4 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 474.0
HKD3_k127_7408418_5 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 426.0
HKD3_k127_7408418_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002045 264.0
HKD3_k127_7408418_7 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000000001146 230.0
HKD3_k127_7408418_8 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000000000000001889 203.0
HKD3_k127_7408418_9 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000008221 157.0
HKD3_k127_741232_0 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 400.0
HKD3_k127_741232_1 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 312.0
HKD3_k127_741232_2 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001617 241.0
HKD3_k127_7414132_0 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 446.0
HKD3_k127_7414132_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 408.0
HKD3_k127_7414132_2 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 400.0
HKD3_k127_7414132_3 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 385.0
HKD3_k127_7414132_4 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000000000000000004442 169.0
HKD3_k127_7414132_5 Response regulator receiver domain - - - 0.0000000000000000000000000000003896 137.0
HKD3_k127_7414132_6 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000002374 128.0
HKD3_k127_7416281_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001084 270.0
HKD3_k127_7416281_1 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000000000000000001447 228.0
HKD3_k127_7416281_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000005817 160.0
HKD3_k127_7422851_0 L-seryl-tRNASec selenium transferase activity K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 411.0
HKD3_k127_7422851_1 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 334.0
HKD3_k127_7422851_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000739 231.0
HKD3_k127_7427702_0 metallocarboxypeptidase activity K14054 - - 0.0 1104.0
HKD3_k127_7427702_1 Ribosomal protein S1 K02945 - - 1.044e-211 672.0
HKD3_k127_7427702_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 447.0
HKD3_k127_7427702_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 331.0
HKD3_k127_7427702_4 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003994 269.0
HKD3_k127_7427702_5 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000002246 192.0
HKD3_k127_7427702_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000000000006154 129.0
HKD3_k127_7427702_7 Binds the 23S rRNA K02909 - - 0.000000000000000000000133 98.0
HKD3_k127_7432055_0 ATPase activity K01990,K19340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 343.0
HKD3_k127_7432055_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 332.0
HKD3_k127_7432055_2 - K01992,K19341 - - 0.00000000000000000000000000000000000000000000000000003833 197.0
HKD3_k127_7432055_3 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000006911 181.0
HKD3_k127_7432055_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000001233 138.0
HKD3_k127_7433521_0 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 429.0
HKD3_k127_7433521_1 restriction endonuclease K07448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 373.0
HKD3_k127_7433521_2 Type II secretion system protein B K02451 - - 0.0000004251 61.0
HKD3_k127_7434962_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 553.0
HKD3_k127_7434962_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 447.0
HKD3_k127_7434962_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 362.0
HKD3_k127_7434962_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 338.0
HKD3_k127_7434962_4 lipoprotein localization to outer membrane K02004,K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 299.0
HKD3_k127_7434962_5 of the major facilitator superfamily K08151 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000138 291.0
HKD3_k127_7434962_6 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000182 256.0
HKD3_k127_7434962_7 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001072 235.0
HKD3_k127_7434962_8 transport - - - 0.00000000000008699 72.0
HKD3_k127_7443692_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 335.0
HKD3_k127_7443692_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 308.0
HKD3_k127_7443692_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000001339 184.0
HKD3_k127_7443692_4 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000009035 140.0
HKD3_k127_7443692_5 metallopeptidase activity - - - 0.0001465 48.0
HKD3_k127_7446787_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 378.0
HKD3_k127_7446787_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 366.0
HKD3_k127_7446787_2 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 336.0
HKD3_k127_7446787_3 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000003641 196.0
HKD3_k127_7446787_4 TIGRFAM 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000008461 70.0
HKD3_k127_7465444_0 Cytochrome c554 and c-prime - - - 4.925e-275 867.0
HKD3_k127_7465444_1 Peptidase family M49 - - - 1.266e-221 703.0
HKD3_k127_7465444_10 Pfam:DUF303 K05970 - 3.1.1.53 0.00000000000000000000000000000004195 129.0
HKD3_k127_7465444_11 Glycogen debranching enzyme - - - 0.00000000000000000000000002545 113.0
HKD3_k127_7465444_12 Glycosyl hydrolase family 63 C-terminal domain - - - 0.00000000001184 66.0
HKD3_k127_7465444_2 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 579.0
HKD3_k127_7465444_3 TIGRFAM anion transporter K03319 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 577.0
HKD3_k127_7465444_5 SMP-30 Gluconolaconase LRE-like K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008957 397.0
HKD3_k127_7465444_6 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 361.0
HKD3_k127_7465444_8 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000007265 266.0
HKD3_k127_7465444_9 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000002565 186.0
HKD3_k127_747185_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 607.0
HKD3_k127_747185_1 COG1073 Hydrolases of the alpha beta superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 512.0
HKD3_k127_747185_2 Pkd domain containing protein - - - 0.0000000000000000000000001726 119.0
HKD3_k127_7474028_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 629.0
HKD3_k127_7474028_1 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 419.0
HKD3_k127_7474028_2 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000002899 209.0
HKD3_k127_7474028_3 - - - - 0.0000000000000000000005701 108.0
HKD3_k127_7501053_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 349.0
HKD3_k127_7501053_1 tRNA processing K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 321.0
HKD3_k127_7501053_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000007517 244.0
HKD3_k127_7501053_3 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000009157 109.0
HKD3_k127_7501053_4 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.000000000009747 68.0
HKD3_k127_7516940_0 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 455.0
HKD3_k127_7516940_1 cAMP biosynthetic process K01768 - 4.6.1.1 0.0000000000000000000000000000000002829 134.0
HKD3_k127_7516940_2 SMART protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.000000000000000000000000000001499 128.0
HKD3_k127_7516940_3 PFAM oxidoreductase domain protein - - - 0.00000000002654 68.0
HKD3_k127_7537025_0 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001297 254.0
HKD3_k127_7537025_1 Serine Threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000002489 218.0
HKD3_k127_7537025_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000008543 145.0
HKD3_k127_7537025_3 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000001034 148.0
HKD3_k127_7560199_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 372.0
HKD3_k127_7560199_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000434 238.0
HKD3_k127_7560199_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000008482 195.0
HKD3_k127_7560199_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000002061 193.0
HKD3_k127_7560199_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000001234 134.0
HKD3_k127_7560199_5 Protein of unknown function (DUF465) - - - 0.000000003995 61.0
HKD3_k127_7565195_0 SAF K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000001517 220.0
HKD3_k127_7565195_1 Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella K02406 - - 0.000000000000000000000000000000000000000000000000000649 194.0
HKD3_k127_7565195_2 - - - - 0.000003398 59.0
HKD3_k127_7578877_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 553.0
HKD3_k127_7578877_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007646 337.0
HKD3_k127_7578877_2 polygalacturonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 342.0
HKD3_k127_7578877_3 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
HKD3_k127_7578877_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000004858 230.0
HKD3_k127_7578877_5 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.000000000000000000000000000000000005617 141.0
HKD3_k127_7593882_0 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 417.0
HKD3_k127_7593882_1 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 382.0
HKD3_k127_7593882_2 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000000000000004897 154.0
HKD3_k127_7593882_3 Carboxypeptidase regulatory-like domain - - - 0.0000000419 63.0
HKD3_k127_7615807_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 625.0
HKD3_k127_7615807_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 592.0
HKD3_k127_7615807_10 Protein of unknown function (DUF1573) - - - 0.0000000000001814 76.0
HKD3_k127_7615807_11 - - - - 0.000006265 54.0
HKD3_k127_7615807_12 Protein of unknown function (DUF1573) - - - 0.00005963 48.0
HKD3_k127_7615807_2 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006026 375.0
HKD3_k127_7615807_3 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001073 265.0
HKD3_k127_7615807_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001095 223.0
HKD3_k127_7615807_5 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000005575 177.0
HKD3_k127_7615807_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000477 123.0
HKD3_k127_7615807_7 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.00000000000000000000004784 106.0
HKD3_k127_7615807_8 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000000000000000003 102.0
HKD3_k127_7615807_9 response to stress - - - 0.0000000000000001704 90.0
HKD3_k127_7651548_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 538.0
HKD3_k127_7651548_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000007244 158.0
HKD3_k127_7666136_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 2.392e-210 676.0
HKD3_k127_7666136_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 311.0
HKD3_k127_7666136_2 - - - - 0.00000000000000000000000000000000000000000000000000001644 199.0
HKD3_k127_7666136_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001348 181.0
HKD3_k127_7666136_4 diguanylate cyclase - - - 0.00000000000000000000000000000002935 128.0
HKD3_k127_7699651_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.476e-225 710.0
HKD3_k127_7699651_1 RNA ligase activity K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 474.0
HKD3_k127_7699651_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 306.0
HKD3_k127_7699651_3 PFAM Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 314.0
HKD3_k127_7699651_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000002067 156.0
HKD3_k127_7699651_5 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000001748 92.0
HKD3_k127_7699651_6 PFAM Preprotein translocase SecG subunit K03075 - - 0.00000000000001899 75.0
HKD3_k127_7704007_0 ATP:ADP antiporter activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 328.0
HKD3_k127_7704007_1 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.00000000000000006349 90.0
HKD3_k127_7704007_2 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000005501 77.0
HKD3_k127_7704007_3 energy transducer activity K03832 - - 0.0000000007539 64.0
HKD3_k127_7720556_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005619 267.0
HKD3_k127_7720556_1 carboxylic acid catabolic process K01736 - 4.2.3.5 0.00000000000000000000001356 106.0
HKD3_k127_7734834_0 Aldo Keto reductase K17744 - 1.1.1.316 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 377.0
HKD3_k127_7734834_1 amidohydrolase K07046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 332.0
HKD3_k127_7734834_2 Alcohol dehydrogenase GroES-like domain K08322 - 1.1.1.380 0.000000000000000000000000000000000000000000000000000000000000614 223.0
HKD3_k127_7734834_3 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000002116 142.0
HKD3_k127_7800514_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 7.501e-306 949.0
HKD3_k127_7800514_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 607.0
HKD3_k127_7800514_10 WD40-like Beta Propeller K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000289 281.0
HKD3_k127_7800514_11 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000002404 228.0
HKD3_k127_7800514_12 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000022 211.0
HKD3_k127_7800514_13 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000001097 204.0
HKD3_k127_7800514_14 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000001997 187.0
HKD3_k127_7800514_15 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.0000000000000000000000000000000000000000000000004535 184.0
HKD3_k127_7800514_16 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000001032 159.0
HKD3_k127_7800514_17 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000007608 138.0
HKD3_k127_7800514_18 Outer membrane lipoprotein - - - 0.0000000000000000000000003251 116.0
HKD3_k127_7800514_19 energy transducer activity K03646,K03832 - - 0.0002217 52.0
HKD3_k127_7800514_2 TIGRFAM Aspartate kinase K12524 - 1.1.1.3,2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 583.0
HKD3_k127_7800514_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 547.0
HKD3_k127_7800514_4 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 490.0
HKD3_k127_7800514_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 395.0
HKD3_k127_7800514_6 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 389.0
HKD3_k127_7800514_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 376.0
HKD3_k127_7800514_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 349.0
HKD3_k127_7800514_9 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 306.0
HKD3_k127_7803381_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000009645 203.0
HKD3_k127_7803381_1 Bacterial Ig-like domain (group 3) - - - 0.0000000000000000000000000000000002169 155.0
HKD3_k127_7803381_2 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000001771 149.0
HKD3_k127_7832828_0 Domain of unknown function (DUF5107) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 409.0
HKD3_k127_7858095_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.00000000000006929 86.0
HKD3_k127_7865372_0 modulates the activities of several proteins which are inactive in their K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003889 253.0
HKD3_k127_7865372_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002223 246.0
HKD3_k127_7900521_0 dipeptidase activity - - - 5.797e-291 902.0
HKD3_k127_7900521_1 Tripartite ATP-independent periplasmic transporter, DctM component K03300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 367.0
HKD3_k127_7900521_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001815 277.0
HKD3_k127_7900521_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 264.0
HKD3_k127_793627_0 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001617 249.0
HKD3_k127_793627_1 NIPSNAP - - - 0.0000000000000000000000000000000009015 131.0
HKD3_k127_793627_2 L-fucose isomerase and related - - - 0.000000000000000000004182 102.0
HKD3_k127_7988480_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 593.0
HKD3_k127_7988480_1 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000002667 216.0
HKD3_k127_7988480_10 - - - - 0.0007563 48.0
HKD3_k127_7988480_2 - - - - 0.00000000000000000000000000000000000000000000000000000000009171 217.0
HKD3_k127_7988480_3 PIN domain K07064 - - 0.00000000000000000000000000001716 123.0
HKD3_k127_7988480_4 COGs COG5616 integral membrane protein - - - 0.00000000000007161 76.0
HKD3_k127_7988480_5 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.000000000002419 68.0
HKD3_k127_7988480_6 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000001202 72.0
HKD3_k127_7988480_7 COGs COG5616 integral membrane protein - - - 0.000000000622 63.0
HKD3_k127_7988480_8 Peptidase family S58 - - - 0.0000001062 55.0
HKD3_k127_7988480_9 Protein kinase domain K12132 - 2.7.11.1 0.00002785 54.0
HKD3_k127_8014236_0 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 522.0
HKD3_k127_8014236_1 Oxidoreductase domain protein - - - 0.000000000000000000000001011 104.0
HKD3_k127_804805_0 Peptidase M14, carboxypeptidase A - - - 3.72e-271 865.0
HKD3_k127_804805_1 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 592.0
HKD3_k127_804805_10 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000001218 126.0
HKD3_k127_804805_11 COG3857 ATP-dependent nuclease, subunit B K16899 - 3.6.4.12 0.0000000000000000000000000001892 134.0
HKD3_k127_804805_12 PFAM Peptidase family M28 - - - 0.00000000000000000007611 105.0
HKD3_k127_804805_2 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 480.0
HKD3_k127_804805_3 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 374.0
HKD3_k127_804805_4 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 318.0
HKD3_k127_804805_5 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000922 234.0
HKD3_k127_804805_6 LmbE homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000001873 229.0
HKD3_k127_804805_7 protein possibly involved in utilization of glycolate and propanediol - - - 0.0000000000000000000000000000000000000000000002997 176.0
HKD3_k127_804805_8 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000000002063 172.0
HKD3_k127_804805_9 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000003533 134.0
HKD3_k127_8097903_0 Tagatose 6 phosphate kinase K16371 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 422.0
HKD3_k127_8097903_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 379.0
HKD3_k127_8097903_2 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 347.0
HKD3_k127_8097903_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003894 278.0
HKD3_k127_8097903_4 Psort location Cytoplasmic, score K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000005329 233.0
HKD3_k127_8097903_5 NHL repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066 - 0.0000000000000000000000000000000000000000000000000000003261 203.0
HKD3_k127_8097903_6 peptide deformylase activity K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000002683 193.0
HKD3_k127_8097903_7 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000001242 192.0
HKD3_k127_8097903_8 Amidohydrolase - - - 0.0000000000847 62.0
HKD3_k127_8097903_9 Belongs to the hyi family K01816 - 5.3.1.22 0.000000004807 66.0
HKD3_k127_81067_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.054e-203 647.0
HKD3_k127_81067_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000004801 201.0
HKD3_k127_81067_2 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000000001648 177.0
HKD3_k127_81067_3 - - - - 0.0000000000000000000000008682 113.0
HKD3_k127_81067_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000021 76.0
HKD3_k127_81067_5 Putative zinc-finger - - - 0.0000004819 59.0
HKD3_k127_81067_6 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.00001652 57.0
HKD3_k127_81067_7 Cell wall-active antibiotics response 4TMS YvqF K11622 - - 0.0009065 44.0
HKD3_k127_8118952_0 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 436.0
HKD3_k127_8118952_1 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000001732 143.0
HKD3_k127_8118952_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.00003901 51.0
HKD3_k127_8183857_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002047 248.0
HKD3_k127_8183857_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000005806 130.0
HKD3_k127_8183857_2 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000113 138.0
HKD3_k127_8183857_3 lipolytic protein G-D-S-L family - - - 0.0000000006306 71.0
HKD3_k127_8210299_1 - - - - 0.000002244 61.0
HKD3_k127_8214812_0 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 560.0
HKD3_k127_8214812_1 COG0524 Sugar kinases, ribokinase K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 350.0
HKD3_k127_8214812_3 Las17-binding protein actin regulator - - - 0.00000000008852 65.0
HKD3_k127_8340441_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 599.0
HKD3_k127_8340441_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 497.0
HKD3_k127_8340441_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 407.0
HKD3_k127_8340441_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001284 282.0
HKD3_k127_8340441_4 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000023 235.0
HKD3_k127_8340441_5 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000004797 126.0
HKD3_k127_8340441_6 - - - - 0.00000000000000000000000006148 114.0
HKD3_k127_8340441_7 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000001574 100.0
HKD3_k127_8340441_8 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000001179 71.0
HKD3_k127_8340441_9 TIGRFAM TonB family K03832 - - 0.0000001974 63.0
HKD3_k127_840183_0 beta-N-acetylhexosaminidase activity K12373 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 615.0
HKD3_k127_840183_1 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 445.0
HKD3_k127_840183_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 374.0
HKD3_k127_840183_3 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001274 284.0
HKD3_k127_840183_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000001071 243.0
HKD3_k127_840183_5 - - - - 0.000000000000000000000000000000000000179 151.0
HKD3_k127_840183_6 oxidoreductase activity K07114 - - 0.00000000000000000000000000000001102 144.0
HKD3_k127_840183_8 - - - - 0.000000000000000000000008872 107.0
HKD3_k127_840183_9 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000002826 91.0
HKD3_k127_8460040_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 545.0
HKD3_k127_8460040_1 prohibitin homologues K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 517.0
HKD3_k127_8460040_2 Putative modulator of DNA gyrase K03592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 388.0
HKD3_k127_8460040_3 Organic Anion Transporter Polypeptide (OATP) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 370.0
HKD3_k127_8460040_4 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 362.0
HKD3_k127_8460040_5 Putative glutamine amidotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 320.0
HKD3_k127_8460040_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000009354 226.0
HKD3_k127_8460040_7 Domain of unknown function (DUF4159) - - - 0.000000000000000000000000000000000000000000000000000000007687 207.0
HKD3_k127_8460040_8 PFAM peptidase M16 domain protein - - - 0.00000000000000000009485 103.0
HKD3_k127_8460040_9 Membrane protein implicated in regulation of membrane protease activity - - - 0.000000004872 65.0
HKD3_k127_8467139_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 425.0
HKD3_k127_8467139_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000000000004532 223.0
HKD3_k127_8467139_2 Cupin domain - - - 0.000000000000000000000005895 104.0
HKD3_k127_8470707_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001051 304.0
HKD3_k127_8471475_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 414.0
HKD3_k127_8471475_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 310.0
HKD3_k127_8471475_10 Ribosomal prokaryotic L21 protein K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000000000001198 111.0
HKD3_k127_8471475_11 Virulence factor BrkB K07058 - - 0.000000000000000000000001071 115.0
HKD3_k127_8471475_12 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000005382 101.0
HKD3_k127_8471475_13 Glycosyl transferase, family 2 - - - 0.0000000000000008726 88.0
HKD3_k127_8471475_14 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000002102 81.0
HKD3_k127_8471475_15 - - - - 0.0000000007761 65.0
HKD3_k127_8471475_2 surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005637 304.0
HKD3_k127_8471475_3 TIGRFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001255 252.0
HKD3_k127_8471475_4 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009045 274.0
HKD3_k127_8471475_5 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000008619 173.0
HKD3_k127_8471475_6 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000001881 153.0
HKD3_k127_8471475_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000006967 134.0
HKD3_k127_8471475_8 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000005545 130.0
HKD3_k127_8471475_9 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000001285 121.0
HKD3_k127_8476594_0 metallocarboxypeptidase activity K14054 - - 0.0 1090.0
HKD3_k127_8476594_1 Hypothetical glycosyl hydrolase 6 - - - 0.0 1016.0
HKD3_k127_8476594_10 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000001289 269.0
HKD3_k127_8476594_11 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000003056 206.0
HKD3_k127_8476594_12 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000001509 191.0
HKD3_k127_8476594_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K13888 - - 0.0000000000000000000000000000000000000000007154 174.0
HKD3_k127_8476594_14 MoaE protein K21142 - 2.8.1.12 0.0000000000000000000003698 96.0
HKD3_k127_8476594_15 Uracil-DNA glycosylase - - - 0.0000000000002651 72.0
HKD3_k127_8476594_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.108e-302 959.0
HKD3_k127_8476594_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 539.0
HKD3_k127_8476594_4 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 524.0
HKD3_k127_8476594_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 406.0
HKD3_k127_8476594_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 385.0
HKD3_k127_8476594_7 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008923 353.0
HKD3_k127_8476594_8 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 299.0
HKD3_k127_8476594_9 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009334 271.0
HKD3_k127_8482638_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.292e-296 916.0
HKD3_k127_8482638_1 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 4.056e-257 813.0
HKD3_k127_8482638_2 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 396.0
HKD3_k127_8482638_3 PFAM Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 321.0
HKD3_k127_8482638_4 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004359 305.0
HKD3_k127_8482638_5 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000000000000000000001111 189.0
HKD3_k127_8482638_6 AAA domain - - - 0.000000000000000000000000000000000001268 161.0
HKD3_k127_8482638_7 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000003859 145.0
HKD3_k127_8482638_8 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000007488 132.0
HKD3_k127_8482638_9 - - - - 0.00000000000000000000001985 103.0
HKD3_k127_8495290_0 Elements of external origin K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 309.0
HKD3_k127_8495290_1 Evidence 2b Function of strongly homologous gene K07497 - - 0.000000000000000000000000000000000000002511 148.0
HKD3_k127_85197_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1534.0
HKD3_k127_85197_2 Putative adhesin - - - 0.00000000000000000001558 98.0
HKD3_k127_8523499_0 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 458.0
HKD3_k127_8523499_1 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000001032 72.0
HKD3_k127_8525504_0 Belongs to the peptidase S16 family - - - 9.927e-257 815.0
HKD3_k127_8525504_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 4.098e-204 658.0
HKD3_k127_8525504_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 326.0
HKD3_k127_8525504_11 phosphoprotein phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 325.0
HKD3_k127_8525504_12 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 307.0
HKD3_k127_8525504_13 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 301.0
HKD3_k127_8525504_14 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 308.0
HKD3_k127_8525504_15 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 300.0
HKD3_k127_8525504_16 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008437 295.0
HKD3_k127_8525504_17 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002336 277.0
HKD3_k127_8525504_18 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001736 255.0
HKD3_k127_8525504_19 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000001872 242.0
HKD3_k127_8525504_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 617.0
HKD3_k127_8525504_20 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001062 238.0
HKD3_k127_8525504_21 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000002571 241.0
HKD3_k127_8525504_22 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000002508 242.0
HKD3_k127_8525504_23 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000002962 229.0
HKD3_k127_8525504_24 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000001792 220.0
HKD3_k127_8525504_25 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000004431 219.0
HKD3_k127_8525504_26 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000001614 173.0
HKD3_k127_8525504_27 Metal dependent phosphohydrolases with conserved 'HD' motif. K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000005329 172.0
HKD3_k127_8525504_28 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000001922 177.0
HKD3_k127_8525504_29 Putative regulatory protein - - - 0.0000000000000000000000000000003823 126.0
HKD3_k127_8525504_3 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 577.0
HKD3_k127_8525504_30 DsrE/DsrF-like family K04085 - - 0.00000000000000001334 87.0
HKD3_k127_8525504_4 PFAM Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 525.0
HKD3_k127_8525504_5 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 478.0
HKD3_k127_8525504_6 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 424.0
HKD3_k127_8525504_7 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006784 392.0
HKD3_k127_8525504_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 387.0
HKD3_k127_8525504_9 1-aminocyclopropane-1-carboxylate deaminase K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 349.0
HKD3_k127_8553584_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.719e-242 760.0
HKD3_k127_8553584_1 PhoH-like protein K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 368.0
HKD3_k127_8553584_10 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000003441 133.0
HKD3_k127_8553584_11 Lipopolysaccharide-assembly - - - 0.00000000000000000001971 100.0
HKD3_k127_8553584_12 - - - - 0.000000000000000008269 93.0
HKD3_k127_8553584_13 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000724 63.0
HKD3_k127_8553584_14 TonB-dependent Receptor Plug Domain - - - 0.000000101 61.0
HKD3_k127_8553584_15 - - - - 0.00000698 50.0
HKD3_k127_8553584_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 405.0
HKD3_k127_8553584_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 347.0
HKD3_k127_8553584_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 317.0
HKD3_k127_8553584_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000008551 242.0
HKD3_k127_8553584_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000002251 224.0
HKD3_k127_8553584_7 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000005379 206.0
HKD3_k127_8553584_8 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.00000000000000000000000000000000005008 136.0
HKD3_k127_8553584_9 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000002564 131.0
HKD3_k127_8568211_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.369e-287 892.0
HKD3_k127_8568211_1 PFAM General secretory system II protein E domain protein K11740 - - 4.649e-230 729.0
HKD3_k127_8568211_10 Domain of unknown function (DUF4434) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001078 279.0
HKD3_k127_8568211_11 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000001322 205.0
HKD3_k127_8568211_12 iron-sulfur cluster biosynthesis transcriptional regulator SufR K09012 - - 0.0000000000000000000000000000000000000001163 160.0
HKD3_k127_8568211_13 Zincin-like metallopeptidase - - - 0.00000000000000000000008787 106.0
HKD3_k127_8568211_14 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 GO:0003674,GO:0003824,GO:0004812,GO:0004818,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006424,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.17 0.0000000000000000002499 91.0
HKD3_k127_8568211_2 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009702 573.0
HKD3_k127_8568211_3 carbohydrate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000882 517.0
HKD3_k127_8568211_4 AIR synthase related protein, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 511.0
HKD3_k127_8568211_5 Bacteriophage N adsorption protein A C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 518.0
HKD3_k127_8568211_6 4-phosphoerythronate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009728 370.0
HKD3_k127_8568211_7 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 362.0
HKD3_k127_8568211_8 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 353.0
HKD3_k127_8568211_9 alanine dehydrogenase activity K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 345.0
HKD3_k127_8569638_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 594.0
HKD3_k127_8569638_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 407.0
HKD3_k127_8569638_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 386.0
HKD3_k127_8569638_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000001027 217.0
HKD3_k127_8569638_4 spore germination K03605 - - 0.0000000000000000000000000000009682 126.0
HKD3_k127_8569638_5 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000000000002095 115.0
HKD3_k127_8569638_6 von Willebrand factor, type A - - - 0.00000006417 56.0
HKD3_k127_8593608_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 600.0
HKD3_k127_8593608_1 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000000000002522 265.0
HKD3_k127_8593608_10 Tetratricopeptide repeat - - - 0.0000000000000000000000006739 111.0
HKD3_k127_8593608_11 Glycosyltransferase like family 2 - - - 0.0000000000000002035 91.0
HKD3_k127_8593608_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000001547 78.0
HKD3_k127_8593608_13 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000003531 72.0
HKD3_k127_8593608_14 COG0800 2-keto-3-deoxy-6-phosphogluconate aldolase K01625 - 4.1.2.14,4.1.3.42 0.000000003428 68.0
HKD3_k127_8593608_15 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000007086 54.0
HKD3_k127_8593608_16 HEAT repeat - - - 0.0001883 52.0
HKD3_k127_8593608_2 protein histidine kinase activity K02484,K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000002224 238.0
HKD3_k127_8593608_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000009297 224.0
HKD3_k127_8593608_4 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000614 223.0
HKD3_k127_8593608_5 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000003864 213.0
HKD3_k127_8593608_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000485 188.0
HKD3_k127_8593608_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001107 173.0
HKD3_k127_8593608_8 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000009053 153.0
HKD3_k127_8593608_9 C4-type zinc ribbon domain K07164 - - 0.000000000000000000000000002814 121.0
HKD3_k127_8598328_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 613.0
HKD3_k127_8598328_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003157 254.0
HKD3_k127_8598328_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000003032 230.0
HKD3_k127_8598328_3 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.00000000000000000000000000000000000000003737 155.0
HKD3_k127_8598328_4 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000002706 119.0
HKD3_k127_8598328_5 Acylphosphatase K01512 - 3.6.1.7 0.000000000000001233 81.0
HKD3_k127_8606432_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 550.0
HKD3_k127_8606432_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 370.0
HKD3_k127_8606432_2 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 295.0
HKD3_k127_8606432_3 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000002291 244.0
HKD3_k127_8606432_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000484 117.0
HKD3_k127_8629032_0 ABC transporter K06147,K18890 - - 1.019e-200 642.0
HKD3_k127_8629032_1 ABC transporter, transmembrane K18889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 586.0
HKD3_k127_8629032_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000002026 112.0
HKD3_k127_8629032_11 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000009689 103.0
HKD3_k127_8629032_12 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.0000000001278 65.0
HKD3_k127_8629032_13 Belongs to the BshC family K22136 - - 0.0000001265 64.0
HKD3_k127_8629032_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 418.0
HKD3_k127_8629032_3 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 297.0
HKD3_k127_8629032_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000004799 246.0
HKD3_k127_8629032_5 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000004079 235.0
HKD3_k127_8629032_6 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.00000000000000000000000000000000000000000000000000000009048 205.0
HKD3_k127_8629032_7 PFAM Peptidase S41 K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000001037 196.0
HKD3_k127_8629032_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000002023 169.0
HKD3_k127_8629032_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000004911 125.0
HKD3_k127_8638288_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 531.0
HKD3_k127_8638288_1 bacterial-type flagellum-dependent cell motility - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 415.0
HKD3_k127_8638288_2 Family 4 glycosyl hydrolase K01222,K07406 - 3.2.1.22,3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 310.0
HKD3_k127_8638288_3 VIT family - - - 0.000000000000000000000000000000000000000000000000000000001374 207.0
HKD3_k127_8638288_4 - - - - 0.0000000000000000000000000000000000000000000002648 181.0
HKD3_k127_8638288_5 Carbohydrate kinase - - - 0.000000000000001184 81.0
HKD3_k127_8638288_6 - - - - 0.00000000000119 78.0
HKD3_k127_8638345_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 3.884e-269 849.0
HKD3_k127_8638345_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 2.121e-254 796.0
HKD3_k127_8638345_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 457.0
HKD3_k127_8638345_3 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 419.0
HKD3_k127_8638345_4 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 313.0
HKD3_k127_8638345_5 Aldo keto - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 294.0
HKD3_k127_8638345_6 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000631 271.0
HKD3_k127_8638345_7 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000003843 274.0
HKD3_k127_8638345_8 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000001543 269.0
HKD3_k127_8638345_9 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000006361 195.0
HKD3_k127_8638638_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.01e-233 732.0
HKD3_k127_8638638_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 3.6.3.14 5.238e-225 706.0
HKD3_k127_8638638_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004388 279.0
HKD3_k127_8638638_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000002201 125.0
HKD3_k127_8638638_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000002977 117.0
HKD3_k127_8638638_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000003812 51.0
HKD3_k127_8713712_0 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 304.0
HKD3_k127_8713712_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001748 256.0
HKD3_k127_8713712_2 protein kinase activity - - - 0.00000000000000000000000000000000000000000000001305 178.0
HKD3_k127_8713712_3 Belongs to the mandelate racemase muconate lactonizing enzyme family K01684 - 4.2.1.6 0.0001063 47.0
HKD3_k127_8726445_0 beta-galactosidase activity K01190,K01219,K12308 - 3.2.1.23,3.2.1.81 9.81e-201 648.0
HKD3_k127_8726445_1 Radical SAM - - - 1.774e-195 622.0
HKD3_k127_8726445_2 glucosamine-6-phosphate deaminase activity K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 484.0
HKD3_k127_8726445_3 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 424.0
HKD3_k127_8726445_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000003194 233.0
HKD3_k127_8726445_5 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000005785 222.0
HKD3_k127_8726445_6 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000001681 196.0
HKD3_k127_8726445_7 cell adhesion involved in biofilm formation K02453 - - 0.00000007964 65.0
HKD3_k127_8726445_8 COG0457 FOG TPR repeat - - - 0.00001175 58.0
HKD3_k127_8733754_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 521.0
HKD3_k127_8733754_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 434.0
HKD3_k127_8747510_0 L-fucose isomerase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 491.0
HKD3_k127_8753650_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008718 252.0
HKD3_k127_8753650_1 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000006372 236.0
HKD3_k127_8753650_2 Domain of unknown function (DUF4115) - - - 0.00000000000000000000003926 110.0
HKD3_k127_8753650_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000006187 107.0
HKD3_k127_8753650_4 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000008341 105.0
HKD3_k127_8753650_5 - - - - 0.0000002897 59.0
HKD3_k127_8753650_6 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000006878 56.0
HKD3_k127_8753650_7 - - - - 0.00007865 48.0
HKD3_k127_8767438_0 FAD binding domain - - - 2.683e-215 676.0
HKD3_k127_8767438_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 556.0
HKD3_k127_8767438_10 Aldolase/RraA K10218 - 4.1.3.17 0.000000000000000000000000000000000000000000000000003707 190.0
HKD3_k127_8767438_11 metallocarboxypeptidase activity - - - 0.00000000000000000000000000000000000000000000000005314 194.0
HKD3_k127_8767438_12 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000002724 187.0
HKD3_k127_8767438_13 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000003178 127.0
HKD3_k127_8767438_2 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 502.0
HKD3_k127_8767438_3 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 372.0
HKD3_k127_8767438_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 356.0
HKD3_k127_8767438_5 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 308.0
HKD3_k127_8767438_6 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.00000000000000000000000000000000000000000000000000000000000000001958 233.0
HKD3_k127_8767438_7 Domain of unknown function K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000769 231.0
HKD3_k127_8767438_8 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000000000000000001815 226.0
HKD3_k127_8767438_9 Glycosyltransferase family 87 - - - 0.00000000000000000000000000000000000000000000000000000000609 214.0
HKD3_k127_8794658_0 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 420.0
HKD3_k127_8794658_1 Psort location Cytoplasmic, score K06971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 370.0
HKD3_k127_8794658_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004216 274.0
HKD3_k127_8794658_3 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004547 276.0
HKD3_k127_8794658_4 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000001568 198.0
HKD3_k127_8796681_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 364.0
HKD3_k127_8796681_1 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 285.0
HKD3_k127_8796681_2 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.000001116 53.0
HKD3_k127_8796681_3 transferase activity, transferring hexosyl groups K14375,K21251,K21260,K21262 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008194,GO:0016740,GO:0016757,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - 0.000002131 59.0
HKD3_k127_8804642_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 6.791e-202 652.0
HKD3_k127_8804642_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 520.0
HKD3_k127_8804642_10 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.00000000000000000000000000002857 124.0
HKD3_k127_8804642_11 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000000006677 115.0
HKD3_k127_8804642_12 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000002684 107.0
HKD3_k127_8804642_13 - - - - 0.000000000002206 71.0
HKD3_k127_8804642_2 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 442.0
HKD3_k127_8804642_3 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 334.0
HKD3_k127_8804642_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000179 271.0
HKD3_k127_8804642_5 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000001115 225.0
HKD3_k127_8804642_6 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000007386 194.0
HKD3_k127_8804642_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001389 162.0
HKD3_k127_8804642_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000002686 147.0
HKD3_k127_8804642_9 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000001577 125.0
HKD3_k127_8813976_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 2.001e-235 734.0
HKD3_k127_8813976_1 xylulokinase activity K00854 - 2.7.1.17 4.746e-204 647.0
HKD3_k127_8813976_10 - - - - 0.0000000005827 68.0
HKD3_k127_8813976_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 543.0
HKD3_k127_8813976_3 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 520.0
HKD3_k127_8813976_4 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 508.0
HKD3_k127_8813976_5 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 364.0
HKD3_k127_8813976_6 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 312.0
HKD3_k127_8813976_7 beta-fructofuranosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000001937 226.0
HKD3_k127_8813976_8 - - - - 0.0000000000002668 72.0
HKD3_k127_8855803_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 364.0
HKD3_k127_8855803_1 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004402 260.0
HKD3_k127_8855803_2 FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation K02416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002471 258.0
HKD3_k127_8855803_3 bacterial-type flagellum organization K02282,K04562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000124 255.0
HKD3_k127_8855803_4 SRP54-type protein, GTPase domain K02404 - - 0.0000000000000000000000000000000000000000000000000003356 199.0
HKD3_k127_8855803_5 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.0002081 53.0
HKD3_k127_8866774_0 Domain of unknown function (DUF4143) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 341.0
HKD3_k127_8866774_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000003061 141.0
HKD3_k127_8888207_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 324.0
HKD3_k127_8888207_1 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000856 271.0
HKD3_k127_8888207_2 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000001728 173.0
HKD3_k127_8888207_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000006905 158.0
HKD3_k127_8888207_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 GO:0000302,GO:0001101,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0016491,GO:0016667,GO:0016672,GO:0016675,GO:0019538,GO:0030091,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0043170,GO:0043546,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0055114,GO:0071704,GO:0097159,GO:1901363,GO:1901530,GO:1901564,GO:1901700 - 0.0000000000000000000000000000000938 128.0
HKD3_k127_8894287_0 Carboxypeptidase regulatory-like domain - - - 1.198e-200 652.0
HKD3_k127_8894287_1 PFAM Peptidase family M3 K01284 - 3.4.15.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 540.0
HKD3_k127_8894287_2 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 391.0
HKD3_k127_8912949_0 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 467.0
HKD3_k127_8912949_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 316.0
HKD3_k127_8912949_2 formamidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 301.0
HKD3_k127_8912949_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000009516 201.0
HKD3_k127_8912949_4 - - - - 0.00000000000000000000000000000000000000000000000004309 201.0
HKD3_k127_8912949_5 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000001629 141.0
HKD3_k127_8912949_6 Sulfatase - - - 0.00000000000000000000000000000000006037 136.0
HKD3_k127_8937243_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 7.264e-219 685.0
HKD3_k127_8937243_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 410.0
HKD3_k127_8937243_10 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000000000005696 143.0
HKD3_k127_8937243_11 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000001042 114.0
HKD3_k127_8937243_2 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 329.0
HKD3_k127_8937243_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 298.0
HKD3_k127_8937243_4 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 297.0
HKD3_k127_8937243_5 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000009751 228.0
HKD3_k127_8937243_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000001488 229.0
HKD3_k127_8937243_7 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000001512 213.0
HKD3_k127_8937243_8 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000000000000000001677 176.0
HKD3_k127_8937243_9 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000000004248 148.0
HKD3_k127_8996366_0 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
HKD3_k127_8996366_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000002253 195.0
HKD3_k127_8996366_2 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000599 150.0
HKD3_k127_9000843_0 Anion-transporting ATPase K01551 - 3.6.3.16 2.413e-197 621.0
HKD3_k127_9000843_1 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 597.0
HKD3_k127_9000843_10 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000157 113.0
HKD3_k127_9000843_11 ATPase activity - - - 0.000000000000000000000008893 114.0
HKD3_k127_9000843_12 Ribbon-helix-helix domain protein - - - 0.00000000003554 65.0
HKD3_k127_9000843_2 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 468.0
HKD3_k127_9000843_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 434.0
HKD3_k127_9000843_4 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009864 411.0
HKD3_k127_9000843_5 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008668 379.0
HKD3_k127_9000843_6 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004516 360.0
HKD3_k127_9000843_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 346.0
HKD3_k127_9000843_8 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 346.0
HKD3_k127_9000843_9 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006947 280.0
HKD3_k127_9038480_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1136.0
HKD3_k127_9038480_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 575.0
HKD3_k127_9038480_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 338.0
HKD3_k127_9038480_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 310.0
HKD3_k127_9038480_4 PFAM Heat shock protein Hsp20 K13993 - - 0.00000000000000000000000000000000000312 142.0
HKD3_k127_9038480_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000001499 106.0
HKD3_k127_9038480_6 CS domain K13993 - - 0.0000000000000000005476 87.0
HKD3_k127_9038480_7 Memo-like protein K06990 - - 0.000000000000000009281 91.0
HKD3_k127_9038480_8 DNA-binding regulatory protein K03088 - - 0.00000000000000002434 92.0
HKD3_k127_9038480_9 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000117 57.0
HKD3_k127_9085309_0 Putative esterase - - - 9.35e-280 874.0
HKD3_k127_9085309_1 Domain of unknown function (DUF5107) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 321.0
HKD3_k127_9085309_2 PHP domain K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000001612 264.0
HKD3_k127_9116960_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains - - - 3.067e-263 820.0
HKD3_k127_9116960_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 1.31e-201 636.0
HKD3_k127_9116960_2 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 332.0
HKD3_k127_9116960_3 Peptidase S46 - - - 0.00000000003291 63.0
HKD3_k127_9148430_0 - - - - 7.591e-288 903.0
HKD3_k127_9148430_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 7.807e-232 722.0
HKD3_k127_9148430_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 610.0
HKD3_k127_9148430_3 Flavin containing amine oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 469.0
HKD3_k127_9148430_4 Predicted membrane protein (DUF2177) - - - 0.0000000000000000000000000000000000000000000000003319 179.0
HKD3_k127_9148824_0 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 1.152e-232 729.0
HKD3_k127_9148824_1 Peptidase dimerisation domain K12941 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 541.0
HKD3_k127_9148824_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000001256 222.0
HKD3_k127_9148824_11 - - - - 0.000000000000000000000000000000000000000000000000000000000001273 215.0
HKD3_k127_9148824_12 - - - - 0.00000000000000000000000000000000000000000000000000000002506 205.0
HKD3_k127_9148824_13 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000001999 181.0
HKD3_k127_9148824_14 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000335 150.0
HKD3_k127_9148824_15 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000000000007662 130.0
HKD3_k127_9148824_16 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.000000000000000000000000000003096 122.0
HKD3_k127_9148824_17 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000001773 70.0
HKD3_k127_9148824_18 - - - - 0.0000002242 58.0
HKD3_k127_9148824_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 517.0
HKD3_k127_9148824_3 proline dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 435.0
HKD3_k127_9148824_4 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 413.0
HKD3_k127_9148824_5 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 363.0
HKD3_k127_9148824_6 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 355.0
HKD3_k127_9148824_7 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 346.0
HKD3_k127_9148824_8 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 334.0
HKD3_k127_9148824_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000007503 226.0
HKD3_k127_9187677_0 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000002256 224.0
HKD3_k127_9187677_1 Sodium Bile acid symporter family K03453 - - 0.00000000000000000000203 105.0
HKD3_k127_9187677_2 Sulfatase K01130 - 3.1.6.1 0.000000006452 66.0
HKD3_k127_9187677_3 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00001934 48.0
HKD3_k127_9194235_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009213 291.0
HKD3_k127_9194235_1 ribonuclease inhibitor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000004452 232.0
HKD3_k127_9194235_2 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.0000000000000000000000000000000000000000000000000000000003201 213.0
HKD3_k127_9194235_3 DinB family - - - 0.0000001884 58.0
HKD3_k127_9269484_0 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 580.0
HKD3_k127_9269484_1 Peptidase family M28 - - - 0.00000000000002181 80.0
HKD3_k127_9269484_2 Sulfatase-modifying factor enzyme 1 - - - 0.0004171 51.0
HKD3_k127_9335709_0 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008338 321.0
HKD3_k127_9335709_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001109 288.0
HKD3_k127_9335709_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001072 229.0
HKD3_k127_9335709_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000001901 164.0
HKD3_k127_9335709_4 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000001227 169.0
HKD3_k127_9335709_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000002047 56.0
HKD3_k127_9340036_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 621.0
HKD3_k127_9340036_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 453.0
HKD3_k127_9340036_10 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 304.0
HKD3_k127_9340036_11 PFAM Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 276.0
HKD3_k127_9340036_12 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000003988 240.0
HKD3_k127_9340036_13 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000008485 227.0
HKD3_k127_9340036_14 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000006527 209.0
HKD3_k127_9340036_15 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000005133 167.0
HKD3_k127_9340036_16 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000001692 173.0
HKD3_k127_9340036_17 PFAM Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.00000000000000000000000000000000000000004564 158.0
HKD3_k127_9340036_18 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000009617 115.0
HKD3_k127_9340036_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 385.0
HKD3_k127_9340036_3 aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 383.0
HKD3_k127_9340036_4 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007563 367.0
HKD3_k127_9340036_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 364.0
HKD3_k127_9340036_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 347.0
HKD3_k127_9340036_7 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 347.0
HKD3_k127_9340036_8 SMART band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 335.0
HKD3_k127_9340036_9 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 319.0
HKD3_k127_9378602_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000003936 216.0
HKD3_k127_9392177_0 serine-type peptidase activity K08676 - - 2.758e-227 716.0
HKD3_k127_9392177_1 PFAM GlcNAc-PI de-N-acetylase K22135 - - 0.00000000000000000000000000000000001274 145.0
HKD3_k127_9392177_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000008873 139.0
HKD3_k127_9495283_0 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000000007042 177.0
HKD3_k127_9495283_1 proline dipeptidase activity K18829 - - 0.0000000000000000000000000000000000000000257 169.0
HKD3_k127_9495283_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000968 99.0
HKD3_k127_9495283_3 Methionine biosynthesis protein MetW - - - 0.0000003927 62.0
HKD3_k127_9562395_0 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 316.0
HKD3_k127_9562395_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000002017 212.0