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Overview

ID MAG01878
Name HKD3_bin.8
Sample SMP0048
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Steroidobacterales
Family Steroidobacteraceae
Genus
Species
Assembly information
Completeness (%) 75.03
Contamination (%) 2.54
GC content (%) 68.0
N50 (bp) 26,198
Genome size (bp) 2,281,791

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2073

Gene name Description KEGG GOs EC E-value Score Sequence
HKD3_k127_117368_0 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 319.0
HKD3_k127_117368_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000007237 246.0
HKD3_k127_117368_2 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000135 193.0
HKD3_k127_1295080_0 transporter - - - 2.263e-248 777.0
HKD3_k127_1295080_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 3.479e-248 775.0
HKD3_k127_1295080_10 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000001088 209.0
HKD3_k127_1295080_11 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000003997 215.0
HKD3_k127_1295080_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000008858 171.0
HKD3_k127_1295080_13 MAPEG family - - - 0.000000000000000000000000000000000001563 142.0
HKD3_k127_1295080_14 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000001463 132.0
HKD3_k127_1295080_15 Rhodanese-related sulfurtransferase K01011 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.8.1.1,2.8.1.2 0.0000000000000000000000000002708 119.0
HKD3_k127_1295080_16 PFAM Membrane protein of K08972 - - 0.00000000000000000000000001322 125.0
HKD3_k127_1295080_17 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000007714 111.0
HKD3_k127_1295080_18 Domain of unknown function (DUF4124) - - - 0.0000000000000006043 85.0
HKD3_k127_1295080_2 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 589.0
HKD3_k127_1295080_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 482.0
HKD3_k127_1295080_4 Glycerol-3-phosphate dehydrogenase K00057 GO:0003674,GO:0003824,GO:0004367,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006072,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0047952,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003164 384.0
HKD3_k127_1295080_5 signal transduction histidine kinase K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 340.0
HKD3_k127_1295080_6 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 336.0
HKD3_k127_1295080_7 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 331.0
HKD3_k127_1295080_8 COG4942 Membrane-bound metallopeptidase - GO:0000920,GO:0001896,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008219,GO:0009273,GO:0009314,GO:0009628,GO:0009987,GO:0012501,GO:0016020,GO:0016787,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0042221,GO:0042493,GO:0042546,GO:0042597,GO:0043085,GO:0044085,GO:0044093,GO:0044464,GO:0050790,GO:0050896,GO:0051301,GO:0051336,GO:0051345,GO:0065007,GO:0065009,GO:0071554,GO:0071840,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000001286 248.0
HKD3_k127_1295080_9 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000006799 210.0
HKD3_k127_1317725_0 Anthranilate synthase component I K01657,K01665 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 550.0
HKD3_k127_1317725_1 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000001347 58.0
HKD3_k127_1343754_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 3.397e-256 807.0
HKD3_k127_1343754_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 592.0
HKD3_k127_1343754_10 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003007 261.0
HKD3_k127_1343754_11 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000002372 244.0
HKD3_k127_1343754_12 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000002673 259.0
HKD3_k127_1343754_13 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000538 242.0
HKD3_k127_1343754_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000006456 225.0
HKD3_k127_1343754_15 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000002396 211.0
HKD3_k127_1343754_16 SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000004697 211.0
HKD3_k127_1343754_17 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000003126 200.0
HKD3_k127_1343754_18 Iron--sulfur cluster insertion protein erpA K15724 - - 0.000000000000000000000000000000000000000000000000001443 184.0
HKD3_k127_1343754_19 - - - - 0.000000000000000000000000003729 110.0
HKD3_k127_1343754_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 500.0
HKD3_k127_1343754_20 - - - - 0.00000000000000001423 91.0
HKD3_k127_1343754_3 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 479.0
HKD3_k127_1343754_4 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 452.0
HKD3_k127_1343754_5 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 414.0
HKD3_k127_1343754_6 TonB-dependent Receptor Plug K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 406.0
HKD3_k127_1343754_7 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 361.0
HKD3_k127_1343754_8 Inositol monophosphatase family K05602 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 322.0
HKD3_k127_1343754_9 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 311.0
HKD3_k127_1431311_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.077e-312 964.0
HKD3_k127_1431311_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000005514 222.0
HKD3_k127_1431311_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0000372,GO:0000375,GO:0000376,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0009058,GO:0009059,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010604,GO:0010628,GO:0015935,GO:0016070,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0031323,GO:0031325,GO:0032991,GO:0033120,GO:0034336,GO:0034337,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043484,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990145,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000006708 215.0
HKD3_k127_1431311_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000003629 212.0
HKD3_k127_144241_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 4.215e-205 646.0
HKD3_k127_144241_1 Polysaccharide biosynthesis/export protein - - - 7.213e-198 661.0
HKD3_k127_144241_10 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 297.0
HKD3_k127_144241_11 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002349 277.0
HKD3_k127_144241_12 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002123 281.0
HKD3_k127_144241_13 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004218 251.0
HKD3_k127_144241_14 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002165 258.0
HKD3_k127_144241_15 - - - - 0.000000000000000000000000000000000000000000000000000000001263 208.0
HKD3_k127_144241_16 Polysaccharide biosynthesis protein K03328 - - 0.0000000000000000000000000000000000000003329 167.0
HKD3_k127_144241_17 lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000006223 161.0
HKD3_k127_144241_18 acetyltransferase - - - 0.00000000000000000000000000000000001211 151.0
HKD3_k127_144241_19 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000002217 144.0
HKD3_k127_144241_2 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03314 - - 8.072e-197 627.0
HKD3_k127_144241_20 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000168 129.0
HKD3_k127_144241_21 Methyltransferase domain - - - 0.0000000000000007994 87.0
HKD3_k127_144241_22 transferase activity, transferring glycosyl groups K07011,K13659 - 2.4.1.264 0.00000000000001732 85.0
HKD3_k127_144241_23 -O-antigen K02847 - - 0.00004218 57.0
HKD3_k127_144241_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 568.0
HKD3_k127_144241_4 PFAM NAD-dependent epimerase dehydratase K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 546.0
HKD3_k127_144241_5 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008815 557.0
HKD3_k127_144241_6 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 505.0
HKD3_k127_144241_7 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 407.0
HKD3_k127_144241_8 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 397.0
HKD3_k127_144241_9 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 327.0
HKD3_k127_1466001_0 COGs COG5616 integral membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 356.0
HKD3_k127_1466001_1 DbpA RNA binding domain K05592,K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360 3.6.4.13 0.0000001108 54.0
HKD3_k127_1511567_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.25e-247 812.0
HKD3_k127_1511567_1 COG2015 Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 568.0
HKD3_k127_1511567_10 MOSC N-terminal beta barrel domain K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001309 253.0
HKD3_k127_1511567_11 PFAM protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000002188 218.0
HKD3_k127_1511567_12 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000001757 220.0
HKD3_k127_1511567_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000216 212.0
HKD3_k127_1511567_14 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000001046 209.0
HKD3_k127_1511567_15 Catalyzes the ATP-dependent phosphorylation of the 3- deoxy-D-manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position K11211 - 2.7.1.166 0.0000000000000000000000000000000000000000000000000000003744 202.0
HKD3_k127_1511567_16 glyoxalase K01759,K03827 - 4.4.1.5 0.000000000000000000000000000000000000000000007946 173.0
HKD3_k127_1511567_17 PFAM glycosyl transferase family 9 - - - 0.0000000000000000000000000000000000000000001392 165.0
HKD3_k127_1511567_18 Zinc-finger domain - - - 0.000000000000000000000001458 104.0
HKD3_k127_1511567_19 - - - - 0.00000000000000000000000164 107.0
HKD3_k127_1511567_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 555.0
HKD3_k127_1511567_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 552.0
HKD3_k127_1511567_4 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006013 507.0
HKD3_k127_1511567_5 heptosyltransferase K12982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 448.0
HKD3_k127_1511567_6 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 395.0
HKD3_k127_1511567_7 DSBA-like thioredoxin domain K14584 - 5.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 306.0
HKD3_k127_1511567_8 COG1538 Outer membrane protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 304.0
HKD3_k127_1511567_9 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001203 279.0
HKD3_k127_1522047_0 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 3.204e-280 866.0
HKD3_k127_1522047_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000413 459.0
HKD3_k127_1522047_2 Phosphoribulokinase / Uridine kinase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 441.0
HKD3_k127_1522047_3 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 407.0
HKD3_k127_1522047_4 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000004093 206.0
HKD3_k127_1559579_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 9.886e-269 843.0
HKD3_k127_1559579_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 9.359e-208 650.0
HKD3_k127_1559579_2 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 441.0
HKD3_k127_1559579_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 352.0
HKD3_k127_1559579_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 341.0
HKD3_k127_1559579_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 301.0
HKD3_k127_1559579_6 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000004218 187.0
HKD3_k127_1559579_7 Competence protein - - - 0.0000000000000000000000000000000000000002351 157.0
HKD3_k127_1559579_8 COG5488 Integral membrane protein - - - 0.0000000000000000009001 95.0
HKD3_k127_1559579_9 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951,K01139 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0015949,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071496,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5,3.1.7.2 0.00003852 47.0
HKD3_k127_1579600_0 Peptidase S46 - - - 2.519e-206 665.0
HKD3_k127_1579600_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 458.0
HKD3_k127_1579600_2 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.000000000000000000000000000000000000000000000000000000003387 205.0
HKD3_k127_163616_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 6.002e-317 980.0
HKD3_k127_163616_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 560.0
HKD3_k127_163616_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0017076,GO:0019904,GO:0022607,GO:0030234,GO:0030554,GO:0032991,GO:0036094,GO:0042802,GO:0042803,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0050790,GO:0050896,GO:0051082,GO:0060589,GO:0060590,GO:0065003,GO:0065007,GO:0065009,GO:0071840,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000001277 171.0
HKD3_k127_163616_11 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000003659 152.0
HKD3_k127_163616_12 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000162 94.0
HKD3_k127_163616_13 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000127 80.0
HKD3_k127_163616_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 GO:0006457,GO:0008150,GO:0009987 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 530.0
HKD3_k127_163616_3 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 505.0
HKD3_k127_163616_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 467.0
HKD3_k127_163616_5 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 401.0
HKD3_k127_163616_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002095 265.0
HKD3_k127_163616_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000006099 244.0
HKD3_k127_163616_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000005343 228.0
HKD3_k127_163616_9 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000231 197.0
HKD3_k127_1659209_0 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 520.0
HKD3_k127_1659209_1 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 511.0
HKD3_k127_1659209_2 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000154 247.0
HKD3_k127_1693527_0 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 3.56e-270 841.0
HKD3_k127_1693527_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 1.025e-251 785.0
HKD3_k127_1693527_2 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 389.0
HKD3_k127_1693527_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 337.0
HKD3_k127_1693527_4 maturation - - - 0.000000000000000000000000000000001892 148.0
HKD3_k127_170582_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1287.0
HKD3_k127_170582_1 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 3.813e-260 812.0
HKD3_k127_170582_10 Putative 2OG-Fe(II) oxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002978 257.0
HKD3_k127_170582_11 Inositol monophosphatase K01092,K18649 - 3.1.3.15,3.1.3.25,3.1.3.93 0.00000000000000000000000000000000000000000000000000000000000000000001139 242.0
HKD3_k127_170582_12 Permease YjgP YjgQ K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000001354 244.0
HKD3_k127_170582_13 permease K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000002142 244.0
HKD3_k127_170582_14 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000003683 232.0
HKD3_k127_170582_15 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000001388 218.0
HKD3_k127_170582_16 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000001483 208.0
HKD3_k127_170582_17 Water Stress and Hypersensitive response - - - 0.000000000000000000000000000000000000001486 160.0
HKD3_k127_170582_18 RDD family - - - 0.000000000000000000000000000000000005011 141.0
HKD3_k127_170582_19 nitrogen regulatory protein PII - - - 0.0000000000000000000000000001304 128.0
HKD3_k127_170582_2 Endothelin-converting enzyme K01415,K07386 - 3.4.24.71 4.688e-240 764.0
HKD3_k127_170582_20 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000001343 119.0
HKD3_k127_170582_21 Acyl CoA binding protein - - - 0.00000000000000000000000001052 112.0
HKD3_k127_170582_22 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.0000000000000000000000002507 110.0
HKD3_k127_170582_23 Cytochrome C' - - - 0.00000000000000000000006107 109.0
HKD3_k127_170582_24 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000000001265 70.0
HKD3_k127_170582_3 FGGY family of carbohydrate kinase, N-terminal domain protein K00854 - 2.7.1.17 3.528e-221 702.0
HKD3_k127_170582_4 to Mus musculus sphingosine-1-phosphate lyase Sgpl1 SWALL O54955 (EMBL AF036894) (568 aa) fasta scores E() K01634 - 4.1.2.27 7.118e-216 691.0
HKD3_k127_170582_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 501.0
HKD3_k127_170582_6 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 493.0
HKD3_k127_170582_7 Major facilitator superfamily K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 451.0
HKD3_k127_170582_8 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 379.0
HKD3_k127_170582_9 associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 396.0
HKD3_k127_1834964_0 TIGRFAM acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 8.247e-228 712.0
HKD3_k127_1834964_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.332e-208 660.0
HKD3_k127_1834964_10 protein involved in tolerance to divalent cations K03926 - - 0.00000000000000000000000000000000001055 140.0
HKD3_k127_1834964_11 Thioredoxin-like - - - 0.000000000000000000000000000004352 131.0
HKD3_k127_1834964_12 Mj0042 family finger-like - - - 0.00000000000000000004432 104.0
HKD3_k127_1834964_13 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000004007 88.0
HKD3_k127_1834964_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 545.0
HKD3_k127_1834964_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 501.0
HKD3_k127_1834964_4 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 411.0
HKD3_k127_1834964_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 399.0
HKD3_k127_1834964_6 Methylates ribosomal protein L11 K02687 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006480,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018011,GO:0018012,GO:0018022,GO:0018023,GO:0018193,GO:0018194,GO:0018205,GO:0019538,GO:0031365,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 299.0
HKD3_k127_1834964_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000004698 202.0
HKD3_k127_1834964_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000265 168.0
HKD3_k127_1834964_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000506 159.0
HKD3_k127_1855760_0 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 297.0
HKD3_k127_1855760_1 Putative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000004797 207.0
HKD3_k127_1855760_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000005891 98.0
HKD3_k127_1893360_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 1.187e-292 925.0
HKD3_k127_1893360_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 1.275e-198 630.0
HKD3_k127_1893360_2 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 591.0
HKD3_k127_1893360_3 PFAM TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 544.0
HKD3_k127_1893360_4 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000008027 199.0
HKD3_k127_1936721_0 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 8.312e-250 785.0
HKD3_k127_1936721_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.295e-198 627.0
HKD3_k127_1936721_10 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01950,K12251 - 3.5.1.53,6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 309.0
HKD3_k127_1936721_11 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 306.0
HKD3_k127_1936721_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000001023 267.0
HKD3_k127_1936721_13 Serine aminopeptidase, S33 K01048 GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000004418 254.0
HKD3_k127_1936721_14 Belongs to the GPAT DAPAT family K00631 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000368 226.0
HKD3_k127_1936721_15 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000001508 141.0
HKD3_k127_1936721_16 Transcriptional regulatory protein, C terminal - - - 0.0000007032 63.0
HKD3_k127_1936721_17 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000005741 58.0
HKD3_k127_1936721_18 exo-alpha-(2->6)-sialidase activity - - - 0.00002416 59.0
HKD3_k127_1936721_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 627.0
HKD3_k127_1936721_3 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 556.0
HKD3_k127_1936721_4 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 455.0
HKD3_k127_1936721_5 HMGL-like K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 452.0
HKD3_k127_1936721_6 HAD-superfamily subfamily IB hydrolase, TIGR01490 K00655,K15781 - 2.3.1.51,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 435.0
HKD3_k127_1936721_7 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 406.0
HKD3_k127_1936721_8 Belongs to the long-chain O-acyltransferase family K00635 GO:0000302,GO:0001666,GO:0003674,GO:0003824,GO:0004144,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0006638,GO:0006639,GO:0006641,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0009058,GO:0009628,GO:0009987,GO:0010035,GO:0016020,GO:0016411,GO:0016740,GO:0016746,GO:0016747,GO:0019432,GO:0030312,GO:0036293,GO:0040007,GO:0042221,GO:0042493,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0044464,GO:0045017,GO:0046460,GO:0046463,GO:0046486,GO:0047196,GO:0050896,GO:0051704,GO:0070482,GO:0071704,GO:0071731,GO:0071944,GO:0097366,GO:1901576,GO:1901698,GO:1901700 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 394.0
HKD3_k127_1936721_9 amino acid activation for nonribosomal peptide biosynthetic process K03641,K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 358.0
HKD3_k127_194162_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1079.0
HKD3_k127_194162_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 589.0
HKD3_k127_194162_10 PFAM MaoC like domain - - - 0.0000000000000000000000000000000000000000000004266 171.0
HKD3_k127_194162_11 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000002363 160.0
HKD3_k127_194162_12 ATP-grasp domain - - - 0.000000000000000000000000000000000000002447 167.0
HKD3_k127_194162_13 PFAM ADP-ribosylation Crystallin J1 - - - 0.0000000000000000000000000000000000005273 158.0
HKD3_k127_194162_14 synthesis repressor, PhaR - - - 0.000000000000000000000000000000000001846 143.0
HKD3_k127_194162_15 PadR family transcriptional regulator K10947 - - 0.0000000000000000000000000000000002406 136.0
HKD3_k127_194162_16 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000002611 134.0
HKD3_k127_194162_17 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000164 116.0
HKD3_k127_194162_18 COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)proteins K03286 - - 0.0000000000000000006141 96.0
HKD3_k127_194162_19 SMART Water Stress and Hypersensitive response - - - 0.0000000000000006766 87.0
HKD3_k127_194162_2 amino acid K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009044 535.0
HKD3_k127_194162_20 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000001061 60.0
HKD3_k127_194162_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 475.0
HKD3_k127_194162_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009415 462.0
HKD3_k127_194162_5 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 460.0
HKD3_k127_194162_6 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 417.0
HKD3_k127_194162_7 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000453 334.0
HKD3_k127_194162_8 Putative sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004791 317.0
HKD3_k127_194162_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 293.0
HKD3_k127_2004027_0 dihydrodipicolinate reductase K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 542.0
HKD3_k127_2004027_1 transporter K03761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 439.0
HKD3_k127_2004027_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 392.0
HKD3_k127_2004027_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000006924 148.0
HKD3_k127_2004027_5 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000009738 87.0
HKD3_k127_2004027_6 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.000000003952 63.0
HKD3_k127_2030281_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 2.541e-238 758.0
HKD3_k127_2030281_1 Belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 7.723e-217 683.0
HKD3_k127_2030281_10 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 438.0
HKD3_k127_2030281_11 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 431.0
HKD3_k127_2030281_12 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003745 413.0
HKD3_k127_2030281_13 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 330.0
HKD3_k127_2030281_14 Glutamine K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 311.0
HKD3_k127_2030281_15 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 250.0
HKD3_k127_2030281_16 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000398 252.0
HKD3_k127_2030281_17 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000002016 233.0
HKD3_k127_2030281_18 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001633 239.0
HKD3_k127_2030281_19 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000173 190.0
HKD3_k127_2030281_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822,K00833 - 2.6.1.18,2.6.1.62 5.39e-215 677.0
HKD3_k127_2030281_20 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000001235 185.0
HKD3_k127_2030281_21 universal stress protein K14055 - - 0.0000000000000000000000000000000000000000002084 173.0
HKD3_k127_2030281_22 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000007217 155.0
HKD3_k127_2030281_23 Protein of unknown function (DUF861) - - - 0.0000000000000000000000000000009957 124.0
HKD3_k127_2030281_24 PFAM Cold-shock protein, DNA-binding - - - 0.000000000000000000000000000005046 123.0
HKD3_k127_2030281_25 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0002902 47.0
HKD3_k127_2030281_3 Belongs to the RtcB family K14415 - 6.5.1.3 4.582e-211 664.0
HKD3_k127_2030281_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000665 617.0
HKD3_k127_2030281_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K12256 - 2.6.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 545.0
HKD3_k127_2030281_6 FAD dependent oxidoreductase K09471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 528.0
HKD3_k127_2030281_7 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625,K00634 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 512.0
HKD3_k127_2030281_8 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 482.0
HKD3_k127_2030281_9 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 463.0
HKD3_k127_2065861_0 TonB dependent receptor - - - 3.839e-249 811.0
HKD3_k127_2065861_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 562.0
HKD3_k127_2065861_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005484 449.0
HKD3_k127_2065861_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000003868 171.0
HKD3_k127_2065861_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000005039 77.0
HKD3_k127_2488695_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 488.0
HKD3_k127_2488695_1 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 434.0
HKD3_k127_2489333_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009488 327.0
HKD3_k127_2489333_1 PFAM Cys Met metabolism K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000004892 169.0
HKD3_k127_2489333_3 - - - - 0.00000003048 61.0
HKD3_k127_2516951_0 Circularly permuted ATP-grasp type 2 - - - 8.013e-244 760.0
HKD3_k127_2516951_1 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 1.76e-235 740.0
HKD3_k127_2516951_10 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 495.0
HKD3_k127_2516951_11 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 475.0
HKD3_k127_2516951_12 ATP-dependent adenylate transferase, transfers adenyl moiety to the MoeD subunit of molybdopterin synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004006 464.0
HKD3_k127_2516951_13 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 433.0
HKD3_k127_2516951_14 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008776 421.0
HKD3_k127_2516951_15 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 404.0
HKD3_k127_2516951_16 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 402.0
HKD3_k127_2516951_17 COG0303 Molybdopterin biosynthesis enzyme K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 364.0
HKD3_k127_2516951_18 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 343.0
HKD3_k127_2516951_19 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003427 329.0
HKD3_k127_2516951_2 acyl-CoA dehydrogenase - - - 4.088e-222 704.0
HKD3_k127_2516951_20 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 325.0
HKD3_k127_2516951_21 A predicted alpha-helical domain with a conserved ER motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 312.0
HKD3_k127_2516951_22 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001084 283.0
HKD3_k127_2516951_23 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K02056,K05776,K10441,K10539,K10542,K10545,K10548 - 3.6.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000001635 280.0
HKD3_k127_2516951_24 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000001541 261.0
HKD3_k127_2516951_25 Transglutaminase-like enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000001398 255.0
HKD3_k127_2516951_26 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000077 232.0
HKD3_k127_2516951_27 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000007422 207.0
HKD3_k127_2516951_28 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000006081 193.0
HKD3_k127_2516951_29 Acyl-CoA synthetase (NDP forming) K09181 - - 0.00000000000000000000000000000002295 136.0
HKD3_k127_2516951_3 TonB-dependent receptor plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 595.0
HKD3_k127_2516951_30 DNA-binding transcription factor activity - - - 0.000000000000000000000000000008974 125.0
HKD3_k127_2516951_31 Chalcone isomerase-like - - - 0.00000000000000000000000000001183 125.0
HKD3_k127_2516951_32 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000000000001354 118.0
HKD3_k127_2516951_33 Molybdopterin K03636 - - 0.000000000000000000000000792 110.0
HKD3_k127_2516951_34 YCII-related domain K09780 - - 0.00000000000000000001724 94.0
HKD3_k127_2516951_35 CHAD domain K01768 - 4.6.1.1 0.00000000005958 73.0
HKD3_k127_2516951_36 - - - - 0.00000001038 62.0
HKD3_k127_2516951_37 - - - - 0.0000283 51.0
HKD3_k127_2516951_4 DNA photolyase K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 583.0
HKD3_k127_2516951_5 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 566.0
HKD3_k127_2516951_6 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 587.0
HKD3_k127_2516951_7 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 583.0
HKD3_k127_2516951_8 Cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 547.0
HKD3_k127_2516951_9 FAD dependent oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 501.0
HKD3_k127_2592184_0 Amidohydrolase family - - - 3.461e-244 767.0
HKD3_k127_2592184_1 arylsulfatase A K01130 - 3.1.6.1 3.595e-234 747.0
HKD3_k127_2592184_10 ABC-type molybdate transport system periplasmic component K02020 GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0015689,GO:0015698,GO:0030973,GO:0043167,GO:0043168,GO:0051179,GO:0051234,GO:1901359 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 309.0
HKD3_k127_2592184_11 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002089 274.0
HKD3_k127_2592184_12 Transcriptional regulator K02019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002814 253.0
HKD3_k127_2592184_13 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000003141 255.0
HKD3_k127_2592184_14 transcription factor binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005762 258.0
HKD3_k127_2592184_15 Thioredoxin - - - 0.00000000000000000000000000000000000000000000000000000000009871 214.0
HKD3_k127_2592184_16 Carbohydrate-selective porin, OprB family K07267 - - 0.0000000000000000000000000000000000000000000000000000000001979 218.0
HKD3_k127_2592184_17 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000001305 177.0
HKD3_k127_2592184_18 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000009549 170.0
HKD3_k127_2592184_19 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000000000004682 139.0
HKD3_k127_2592184_2 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 565.0
HKD3_k127_2592184_20 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.0000000000000000000000007159 116.0
HKD3_k127_2592184_21 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07662 - - 0.000000000004327 76.0
HKD3_k127_2592184_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 576.0
HKD3_k127_2592184_4 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 472.0
HKD3_k127_2592184_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 450.0
HKD3_k127_2592184_6 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 411.0
HKD3_k127_2592184_7 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 363.0
HKD3_k127_2592184_8 abc transporter, permease K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 351.0
HKD3_k127_2592184_9 PPIC-type PPIASE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 335.0
HKD3_k127_2706045_0 orn lys arg decarboxylase K01583 - 4.1.1.19 0.0 1350.0
HKD3_k127_2706045_1 Aminotransferase class I and II K09758 - 4.1.1.12 1.292e-254 812.0
HKD3_k127_2706045_10 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009772 393.0
HKD3_k127_2706045_11 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 381.0
HKD3_k127_2706045_12 Predicted Permease Membrane Region K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 371.0
HKD3_k127_2706045_13 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000164 280.0
HKD3_k127_2706045_14 Possible lysine decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008592 278.0
HKD3_k127_2706045_15 Protein of unknown function (DUF3302) - - - 0.0000000000000000000000000000000007187 145.0
HKD3_k127_2706045_16 Glutaminase K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016043,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0040008,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045926,GO:0046394,GO:0046395,GO:0048519,GO:0050789,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.000000000000002748 76.0
HKD3_k127_2706045_2 Predicted Permease Membrane Region - - - 4.75e-232 730.0
HKD3_k127_2706045_3 Amino acid permease K03294,K16238 - - 2.644e-218 690.0
HKD3_k127_2706045_4 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.523e-211 664.0
HKD3_k127_2706045_5 Asparaginase K01424 - 3.5.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 490.0
HKD3_k127_2706045_6 Aspartate alanine antiporter family protein 1 K07085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 491.0
HKD3_k127_2706045_7 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 492.0
HKD3_k127_2706045_8 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 448.0
HKD3_k127_2706045_9 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 420.0
HKD3_k127_2873873_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00244 - 1.3.5.4 1.36e-321 996.0
HKD3_k127_2873873_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 3.58e-269 846.0
HKD3_k127_2873873_10 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001345 244.0
HKD3_k127_2873873_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000003751 212.0
HKD3_k127_2873873_12 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000000005656 166.0
HKD3_k127_2873873_13 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000003437 162.0
HKD3_k127_2873873_14 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000002513 143.0
HKD3_k127_2873873_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000121 109.0
HKD3_k127_2873873_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.784e-227 711.0
HKD3_k127_2873873_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 6.407e-204 650.0
HKD3_k127_2873873_4 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 574.0
HKD3_k127_2873873_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 561.0
HKD3_k127_2873873_6 fumarate reductase respiratory complex transmembrane subunit K00246 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 324.0
HKD3_k127_2873873_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 309.0
HKD3_k127_2873873_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008863 299.0
HKD3_k127_2873873_9 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000003677 231.0
HKD3_k127_2943640_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 444.0
HKD3_k127_2943640_1 Ring hydroxylating alpha subunit (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009176 342.0
HKD3_k127_2943640_2 P-aminobenzoate N-oxygenase AurF - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 301.0
HKD3_k127_2943640_3 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000207 278.0
HKD3_k127_2943640_4 PFAM regulatory protein, MerR - - - 0.00000000000000000000000000000001026 138.0
HKD3_k127_2943640_5 ferredoxin K04755 - - 0.000000000000000000000000000002578 122.0
HKD3_k127_298399_0 UPF0313 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 542.0
HKD3_k127_298399_1 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 561.0
HKD3_k127_298399_2 Domain of unknown function (DUF4032) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 410.0
HKD3_k127_298399_3 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003871 340.0
HKD3_k127_298399_4 Glycine zipper - - - 0.000000000000000000000000000000000000000000000000000005291 197.0
HKD3_k127_3028664_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1204.0
HKD3_k127_3028664_1 TIGRFAM type IV-A pilus assembly ATPase PilB K02652 - - 1.364e-226 715.0
HKD3_k127_3028664_10 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 470.0
HKD3_k127_3028664_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 463.0
HKD3_k127_3028664_12 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 401.0
HKD3_k127_3028664_13 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 397.0
HKD3_k127_3028664_14 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 398.0
HKD3_k127_3028664_15 Protein of unknown function (DUF354) K09726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 364.0
HKD3_k127_3028664_16 Histidine kinase K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 364.0
HKD3_k127_3028664_17 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02464,K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 347.0
HKD3_k127_3028664_18 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 326.0
HKD3_k127_3028664_19 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 313.0
HKD3_k127_3028664_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 6.157e-209 658.0
HKD3_k127_3028664_20 Protein of unknown function (DUF229) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002286 297.0
HKD3_k127_3028664_21 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007759 269.0
HKD3_k127_3028664_22 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.000000000000000000000000000000000000000000000000000000000000000000003804 245.0
HKD3_k127_3028664_23 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000008683 219.0
HKD3_k127_3028664_24 - - - - 0.000000000000000000000000000000000000000000000000000000000003544 230.0
HKD3_k127_3028664_25 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 GO:0003674,GO:0003824,GO:0008119,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008757,GO:0010035,GO:0010038,GO:0016740,GO:0016741,GO:0032259,GO:0042221,GO:0046690,GO:0050896 2.1.1.67 0.00000000000000000000000000000000000000000000000000000000001404 215.0
HKD3_k127_3028664_26 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000006833 207.0
HKD3_k127_3028664_27 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000000000000000002049 214.0
HKD3_k127_3028664_28 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000009544 189.0
HKD3_k127_3028664_29 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000001431 179.0
HKD3_k127_3028664_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 597.0
HKD3_k127_3028664_30 pilus assembly protein major pilin PilA K02650,K02655 - - 0.0000000000000000000000000000000000000000003624 164.0
HKD3_k127_3028664_31 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000007565 140.0
HKD3_k127_3028664_32 - - - - 0.000000000000000000000000007017 122.0
HKD3_k127_3028664_33 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 - 0.000000000000000003855 87.0
HKD3_k127_3028664_34 Protein of unknown function (DUF721) - - - 0.000885 46.0
HKD3_k127_3028664_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481,K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 523.0
HKD3_k127_3028664_5 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 GO:0003674,GO:0003824,GO:0004774,GO:0004775,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016874,GO:0016877,GO:0016878,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 513.0
HKD3_k127_3028664_6 Type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004241 496.0
HKD3_k127_3028664_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 491.0
HKD3_k127_3028664_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 479.0
HKD3_k127_3028664_9 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 520.0
HKD3_k127_3219677_0 Aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 460.0
HKD3_k127_3219677_1 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 429.0
HKD3_k127_3219677_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000299 209.0
HKD3_k127_3219677_11 Pfam Glycosyl transferase family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.000000000000000000000000000000000000000000000002566 186.0
HKD3_k127_3219677_2 PFAM Peptidase family M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 432.0
HKD3_k127_3219677_3 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 426.0
HKD3_k127_3219677_4 electron transfer flavoprotein beta subunit K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 345.0
HKD3_k127_3219677_5 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 261.0
HKD3_k127_3219677_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001126 269.0
HKD3_k127_3219677_7 Polysaccharide pyruvyl transferase K16710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008743 264.0
HKD3_k127_3219677_8 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002071 260.0
HKD3_k127_3219677_9 transcriptional regulator K05818 - - 0.00000000000000000000000000000000000000000000000000000000000000000007932 242.0
HKD3_k127_3228_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.111e-282 874.0
HKD3_k127_3228_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 1.131e-201 640.0
HKD3_k127_3228_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000002199 91.0
HKD3_k127_3228_11 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000001863 74.0
HKD3_k127_3228_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0000166,GO:0001510,GO:0001882,GO:0001883,GO:0002097,GO:0002098,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006457,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009268,GO:0009451,GO:0009628,GO:0009636,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0030488,GO:0030955,GO:0031420,GO:0032259,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0042221,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0061077,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007262 504.0
HKD3_k127_3228_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 465.0
HKD3_k127_3228_4 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 420.0
HKD3_k127_3228_5 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 407.0
HKD3_k127_3228_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 359.0
HKD3_k127_3228_7 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002722 268.0
HKD3_k127_3228_8 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005331 279.0
HKD3_k127_3228_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000000006744 124.0
HKD3_k127_3239508_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 589.0
HKD3_k127_3239508_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 458.0
HKD3_k127_3239508_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 404.0
HKD3_k127_3239508_3 - - - - 0.000000000000000000000000000003502 124.0
HKD3_k127_3239508_4 - - - - 0.000005682 48.0
HKD3_k127_3341867_0 cation transport ATPase K01533 - 3.6.3.4 4.939e-208 678.0
HKD3_k127_3341867_1 TIGRFAM cytochrome c oxidase accessory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005247 603.0
HKD3_k127_3341867_10 Cytochrome oxidase maturation protein - - - 0.00000000000007486 74.0
HKD3_k127_3341867_11 - - - - 0.000000000002971 72.0
HKD3_k127_3341867_12 Cbb3-type cytochrome oxidase K00407 - - 0.00000000002586 66.0
HKD3_k127_3341867_13 FixH K09926 - - 0.000000004609 59.0
HKD3_k127_3341867_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 394.0
HKD3_k127_3341867_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 379.0
HKD3_k127_3341867_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 332.0
HKD3_k127_3341867_5 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 302.0
HKD3_k127_3341867_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001486 270.0
HKD3_k127_3341867_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000001764 173.0
HKD3_k127_3341867_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000002233 137.0
HKD3_k127_3341867_9 Protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.00000000000001293 77.0
HKD3_k127_3586935_0 Alkyl hydroperoxide reductase K03387 - - 6.226e-257 801.0
HKD3_k127_3586935_1 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 509.0
HKD3_k127_3586935_10 nucleic acid-binding protein, contains PIN domain - - - 0.0000000000000000000000000000000000000000000000001126 180.0
HKD3_k127_3586935_11 glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000000000000004188 169.0
HKD3_k127_3586935_12 prlF antitoxin for toxin YhaV_toxin - - - 0.00000000000000002959 84.0
HKD3_k127_3586935_13 - - - - 0.0000000000009992 77.0
HKD3_k127_3586935_14 - - - - 0.000000000001281 69.0
HKD3_k127_3586935_15 - - - - 0.0007066 46.0
HKD3_k127_3586935_2 GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 391.0
HKD3_k127_3586935_3 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004921 346.0
HKD3_k127_3586935_4 Helix-turn-helix type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 319.0
HKD3_k127_3586935_5 PFAM OsmC family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 292.0
HKD3_k127_3586935_6 diguanylate cyclase K13069 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000705 241.0
HKD3_k127_3586935_7 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000005775 191.0
HKD3_k127_3586935_9 Sensors of blue-light using FAD - - - 0.00000000000000000000000000000000000000000000000007865 181.0
HKD3_k127_3637150_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.231e-272 856.0
HKD3_k127_3637150_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 1.34e-238 751.0
HKD3_k127_3637150_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000001026 238.0
HKD3_k127_3637150_11 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 0.0000000000000000000000000000000000000000000000000005178 203.0
HKD3_k127_3637150_12 OmpW family K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000005052 169.0
HKD3_k127_3637150_13 - - - - 0.0000000004269 72.0
HKD3_k127_3637150_14 Belongs to the ompA family K03286 - - 0.000001141 60.0
HKD3_k127_3637150_15 Protein of unknown function (DUF2505) - - - 0.0004568 49.0
HKD3_k127_3637150_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K20034 - 6.2.1.44 1.571e-212 673.0
HKD3_k127_3637150_3 Hydroxymethylglutaryl-coenzyme A reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 574.0
HKD3_k127_3637150_4 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 529.0
HKD3_k127_3637150_5 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 468.0
HKD3_k127_3637150_6 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007851 423.0
HKD3_k127_3637150_7 COG1454 Alcohol dehydrogenase, class IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 390.0
HKD3_k127_3637150_8 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 359.0
HKD3_k127_3637150_9 SBF-like CPA transporter family (DUF4137) K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 332.0
HKD3_k127_3639116_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.489e-218 683.0
HKD3_k127_3639116_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 410.0
HKD3_k127_3676718_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2571.0
HKD3_k127_3676718_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 7.191e-318 983.0
HKD3_k127_3676718_10 Molydopterin dinucleotide binding domain K16964 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.8.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 585.0
HKD3_k127_3676718_11 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 540.0
HKD3_k127_3676718_12 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 497.0
HKD3_k127_3676718_13 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006987 464.0
HKD3_k127_3676718_14 valine-pyruvate transaminase activity K00835 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009042,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019752,GO:0030632,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 447.0
HKD3_k127_3676718_15 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 443.0
HKD3_k127_3676718_16 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 438.0
HKD3_k127_3676718_17 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009501 428.0
HKD3_k127_3676718_18 Phospholipase D. Active site motifs. K06132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 399.0
HKD3_k127_3676718_19 4Fe-4S dicluster domain K17048,K17051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 399.0
HKD3_k127_3676718_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0003952,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016020,GO:0016874,GO:0016879,GO:0016880,GO:0016884,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 7.755e-306 951.0
HKD3_k127_3676718_20 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 395.0
HKD3_k127_3676718_21 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 341.0
HKD3_k127_3676718_22 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 359.0
HKD3_k127_3676718_23 Protein of unknown function (DUF1838) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 338.0
HKD3_k127_3676718_24 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 332.0
HKD3_k127_3676718_25 SMART Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 302.0
HKD3_k127_3676718_26 Catalyzes the conversion of N-formimidoyl-L-glutamate to L-glutamate and formamide K01479,K01480 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016813,GO:0019439,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046395,GO:0046483,GO:0046700,GO:0052803,GO:0052805,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.3.11,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 292.0
HKD3_k127_3676718_27 PFAM LemA family protein K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
HKD3_k127_3676718_28 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001703 267.0
HKD3_k127_3676718_29 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002241 280.0
HKD3_k127_3676718_3 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.956e-301 930.0
HKD3_k127_3676718_30 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008683 253.0
HKD3_k127_3676718_31 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000001335 228.0
HKD3_k127_3676718_32 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000008942 217.0
HKD3_k127_3676718_33 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000002576 208.0
HKD3_k127_3676718_34 Belongs to the Nudix hydrolase family K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000007804 200.0
HKD3_k127_3676718_35 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000004005 217.0
HKD3_k127_3676718_36 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000000000000000003217 198.0
HKD3_k127_3676718_37 protein conserved in bacteria K09793 - - 0.00000000000000000000000000000000000000000000000002109 183.0
HKD3_k127_3676718_38 Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000002322 182.0
HKD3_k127_3676718_39 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000005606 181.0
HKD3_k127_3676718_4 ATP-dependent helicase K03579 - 3.6.4.13 2.98e-257 826.0
HKD3_k127_3676718_40 TPM domain - - - 0.0000000000000000000000000000000000000000000000008699 188.0
HKD3_k127_3676718_41 AMMECR1 K06990 - - 0.000000000000000000000000000000000000000000000007883 179.0
HKD3_k127_3676718_42 - - - - 0.0000000000000000000000000000000000000000000001803 174.0
HKD3_k127_3676718_43 Acetyltransferases including N-acetylases of ribosomal proteins - - - 0.000000000000000000000000000000000000000003643 168.0
HKD3_k127_3676718_44 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000001844 160.0
HKD3_k127_3676718_45 Type II secretory pathway, component - - - 0.0000000000000000000000000000000000000001751 162.0
HKD3_k127_3676718_46 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000001156 159.0
HKD3_k127_3676718_47 - - - - 0.000000000000000000000000000000000005656 147.0
HKD3_k127_3676718_48 Protein of unknown function (DUF1232) - - - 0.00000000000000000000000000000000001252 142.0
HKD3_k127_3676718_49 - - - - 0.0000000000000000000000000000000008484 139.0
HKD3_k127_3676718_5 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.969e-246 780.0
HKD3_k127_3676718_50 pfam nlp p60 K13695 - - 0.0000000000000000000000000000001949 135.0
HKD3_k127_3676718_51 - - - - 0.00000000000000000000000000000111 131.0
HKD3_k127_3676718_52 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000000000001081 122.0
HKD3_k127_3676718_53 family UPF0016 - - - 0.000000000000000000000000001369 114.0
HKD3_k127_3676718_54 - - - - 0.000000000000000000000000003664 129.0
HKD3_k127_3676718_55 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000002719 110.0
HKD3_k127_3676718_56 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000007573 98.0
HKD3_k127_3676718_57 Protein of unknown function (DUF1475) - - - 0.000000000000000000499 97.0
HKD3_k127_3676718_58 - - - - 0.000000000000004194 79.0
HKD3_k127_3676718_59 AAA domain - - - 0.00000000000005787 82.0
HKD3_k127_3676718_6 Homospermidine synthase K00808 - 2.5.1.44 9.322e-233 743.0
HKD3_k127_3676718_60 - - - - 0.0000000000054 78.0
HKD3_k127_3676718_61 Domain in cystathionine beta-synthase and other proteins. K04767 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.000000001479 68.0
HKD3_k127_3676718_62 Nitrate reductase delta subunit - - - 0.000000008878 68.0
HKD3_k127_3676718_63 SMART Peptidoglycan-binding Lysin subgroup K16291 - - 0.00002823 53.0
HKD3_k127_3676718_7 Peptidase family M13 K07386 - - 3.133e-202 653.0
HKD3_k127_3676718_8 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 3.176e-201 648.0
HKD3_k127_3676718_9 Pyruvate formate lyase-activating protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 587.0
HKD3_k127_3711864_0 Phosphoglycerol transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 582.0
HKD3_k127_3766696_0 COG0616 Periplasmic serine proteases (ClpP class) K04773 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016020,GO:0016021,GO:0016485,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0034641,GO:0043170,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0051604,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 476.0
HKD3_k127_3766696_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000007648 142.0
HKD3_k127_3794326_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1083.0
HKD3_k127_3794326_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 2.297e-314 976.0
HKD3_k127_3794326_10 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009266,GO:0009409,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000002508 100.0
HKD3_k127_3794326_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.955e-213 673.0
HKD3_k127_3794326_3 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 299.0
HKD3_k127_3794326_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000002447 265.0
HKD3_k127_3794326_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000108 187.0
HKD3_k127_3794326_6 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.00000000000000000000000000000000000000000000000273 181.0
HKD3_k127_3794326_7 synthesis repressor, PhaR - - - 0.0000000000000000000000000000000000001073 147.0
HKD3_k127_3794326_8 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000007629 127.0
HKD3_k127_3794326_9 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.000000000000000000000007825 114.0
HKD3_k127_3809565_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1179.0
HKD3_k127_3809565_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 337.0
HKD3_k127_3809565_2 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 330.0
HKD3_k127_3810961_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 2.96e-322 1007.0
HKD3_k127_3810961_1 Peptidase family M3 K01414 - 3.4.24.70 1.055e-260 821.0
HKD3_k127_3810961_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 287.0
HKD3_k127_3810961_11 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000131 287.0
HKD3_k127_3810961_12 Protein containing LysM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004796 282.0
HKD3_k127_3810961_13 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000009045 250.0
HKD3_k127_3810961_14 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007078 249.0
HKD3_k127_3810961_15 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002095 246.0
HKD3_k127_3810961_16 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000000006615 225.0
HKD3_k127_3810961_17 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000000000000000000000000000002363 207.0
HKD3_k127_3810961_18 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000002773 214.0
HKD3_k127_3810961_19 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000000000002747 171.0
HKD3_k127_3810961_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 636.0
HKD3_k127_3810961_20 Sigma-70 region 2 - - - 0.00000000000000000000000000000000000000000002343 167.0
HKD3_k127_3810961_21 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000000000000000001497 163.0
HKD3_k127_3810961_22 - - - - 0.0000000000000000002499 93.0
HKD3_k127_3810961_23 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000001601 93.0
HKD3_k127_3810961_24 Protein of unknown function (DUF3379) - - - 0.0000000000001836 80.0
HKD3_k127_3810961_25 E3 Ubiquitin ligase - - - 0.000000008641 62.0
HKD3_k127_3810961_26 - - - - 0.0002311 48.0
HKD3_k127_3810961_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 517.0
HKD3_k127_3810961_4 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 512.0
HKD3_k127_3810961_5 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 361.0
HKD3_k127_3810961_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 366.0
HKD3_k127_3810961_7 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 307.0
HKD3_k127_3810961_8 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 301.0
HKD3_k127_3810961_9 PFAM methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 285.0
HKD3_k127_3887842_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 3.451e-319 983.0
HKD3_k127_3887842_1 Belongs to the GcvT family K00302 - 1.5.3.1 6.62e-288 917.0
HKD3_k127_3887842_10 Regulatory protein, FmdB family - - - 0.00000000000000000000001391 106.0
HKD3_k127_3887842_11 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000001469 98.0
HKD3_k127_3887842_12 Sarcosine oxidase, gamma subunit K00305 - 1.5.3.1 0.00000000000000009043 86.0
HKD3_k127_3887842_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 9.125e-272 847.0
HKD3_k127_3887842_3 Sarcosine oxidase, subunit beta K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 529.0
HKD3_k127_3887842_4 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 432.0
HKD3_k127_3887842_5 COG0841 Cation multidrug efflux pump K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000002617 233.0
HKD3_k127_3887842_6 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000006818 229.0
HKD3_k127_3887842_7 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000002636 156.0
HKD3_k127_3887842_8 Sarcosine oxidase, delta subunit family K00304 - 1.5.3.1 0.0000000000000000000000000000000002078 137.0
HKD3_k127_3887842_9 Cupin domain - - - 0.000000000000000000000000000004866 133.0
HKD3_k127_3938244_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006351,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0018130,GO:0019438,GO:0032774,GO:0034335,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042493,GO:0042623,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097659,GO:0140097,GO:1901360,GO:1901362,GO:1901363,GO:1901576 5.99.1.3 0.0 1187.0
HKD3_k127_3938244_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 609.0
HKD3_k127_3938244_10 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 295.0
HKD3_k127_3938244_11 reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001383 269.0
HKD3_k127_3938244_12 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000007214 263.0
HKD3_k127_3938244_13 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000005054 251.0
HKD3_k127_3938244_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000004466 239.0
HKD3_k127_3938244_15 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000813 203.0
HKD3_k127_3938244_16 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000004127 197.0
HKD3_k127_3938244_17 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000003251 188.0
HKD3_k127_3938244_18 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000002183 173.0
HKD3_k127_3938244_19 sister chromatid segregation - - - 0.0000000000000000000000000000000001258 145.0
HKD3_k127_3938244_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 543.0
HKD3_k127_3938244_20 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000005309 130.0
HKD3_k127_3938244_21 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000009384 119.0
HKD3_k127_3938244_22 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 GO:0000175,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004532,GO:0004536,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0008946,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0016896,GO:0019439,GO:0034611,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0140097,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00002367 46.0
HKD3_k127_3938244_3 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 535.0
HKD3_k127_3938244_4 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 GO:0003674,GO:0003824,GO:0004648,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006520,GO:0006553,GO:0006563,GO:0006564,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009085,GO:0009089,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019752,GO:0019842,GO:0030170,GO:0033359,GO:0034641,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046394,GO:0046451,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901615,GO:1901617 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 499.0
HKD3_k127_3938244_5 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000086 495.0
HKD3_k127_3938244_6 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 465.0
HKD3_k127_3938244_7 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 439.0
HKD3_k127_3938244_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 345.0
HKD3_k127_3938244_9 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005379 300.0
HKD3_k127_3991265_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 425.0
HKD3_k127_3991265_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 414.0
HKD3_k127_3991265_10 Domain of unknown function (DUF4126) - - - 0.00000000000000000000000000000000000000000000001053 177.0
HKD3_k127_3991265_11 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000001958 106.0
HKD3_k127_3991265_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 421.0
HKD3_k127_3991265_3 Surface antigen variable number K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000724 346.0
HKD3_k127_3991265_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 321.0
HKD3_k127_3991265_5 NADH pyrophosphatase zinc ribbon domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000292 292.0
HKD3_k127_3991265_6 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001522 268.0
HKD3_k127_3991265_7 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003881 250.0
HKD3_k127_3991265_8 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002299 251.0
HKD3_k127_3991265_9 Hydrolase of X-linked nucleoside diphosphate N terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
HKD3_k127_3998925_0 FAD dependent oxidoreductase K07077 - - 2.154e-227 715.0
HKD3_k127_3998925_1 Major facilitator superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 527.0
HKD3_k127_3998925_10 TIGRFAM Cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 297.0
HKD3_k127_3998925_11 Belongs to the UPF0758 family K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 304.0
HKD3_k127_3998925_12 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003104 280.0
HKD3_k127_3998925_13 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005852 298.0
HKD3_k127_3998925_14 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000692 274.0
HKD3_k127_3998925_15 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000003475 245.0
HKD3_k127_3998925_16 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000001411 242.0
HKD3_k127_3998925_17 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.00000000000000000000000000000000000000000000000000000000001281 213.0
HKD3_k127_3998925_18 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000006495 208.0
HKD3_k127_3998925_19 UPF0056 membrane protein K05595 - - 0.000000000000000000000000000000000000000000001105 173.0
HKD3_k127_3998925_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 480.0
HKD3_k127_3998925_20 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000004854 158.0
HKD3_k127_3998925_21 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000009364 132.0
HKD3_k127_3998925_22 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000001836 134.0
HKD3_k127_3998925_23 RNA polymerase sigma factor RpoH K03089 - - 0.0000000000000000000000000000004034 126.0
HKD3_k127_3998925_24 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000005663 123.0
HKD3_k127_3998925_25 Rieske 2Fe-2S - - - 0.00000000000000000000000003374 125.0
HKD3_k127_3998925_26 - - - - 0.000000000000000000007423 96.0
HKD3_k127_3998925_27 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000000009682 91.0
HKD3_k127_3998925_28 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000007823 91.0
HKD3_k127_3998925_29 Pfam Transposase IS66 - - - 0.000000002838 69.0
HKD3_k127_3998925_3 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 483.0
HKD3_k127_3998925_30 PFAM Exopolysaccharide synthesis ExoD - - - 0.000000004011 59.0
HKD3_k127_3998925_4 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 399.0
HKD3_k127_3998925_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 394.0
HKD3_k127_3998925_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 340.0
HKD3_k127_3998925_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 304.0
HKD3_k127_3998925_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 GO:0000287,GO:0003674,GO:0003824,GO:0004588,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009468 291.0
HKD3_k127_3998925_9 Bacterial virulence factor lipase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006757 310.0
HKD3_k127_4006399_0 Cysteine synthase K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
HKD3_k127_4006399_1 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000008957 211.0
HKD3_k127_4006399_2 - - - - 0.00000000000006905 81.0
HKD3_k127_4103862_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.463e-296 921.0
HKD3_k127_4103862_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 5.282e-252 784.0
HKD3_k127_4103862_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 6.67e-207 655.0
HKD3_k127_4103862_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 1.467e-197 617.0
HKD3_k127_4103862_4 PFAM O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 300.0
HKD3_k127_4103862_5 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000001198 129.0
HKD3_k127_4103862_6 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.00000000000000000000000002672 116.0
HKD3_k127_4114669_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000003426 237.0
HKD3_k127_4114669_1 Tetratricopeptide repeat - - - 0.000000000000000001709 99.0
HKD3_k127_4172472_0 Protein of unknown function (DUF3604) - - - 0.0 1083.0
HKD3_k127_4172472_1 Pyridine nucleotide-disulphide oxidoreductase - - - 5.81e-285 901.0
HKD3_k127_4172472_10 hydrolase activity, acting on ester bonds K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 455.0
HKD3_k127_4172472_11 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 440.0
HKD3_k127_4172472_12 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 444.0
HKD3_k127_4172472_13 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004138 433.0
HKD3_k127_4172472_14 surface antigen variable number repeat protein K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 435.0
HKD3_k127_4172472_15 Belongs to the glutaminase family K01425 - 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 325.0
HKD3_k127_4172472_16 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 318.0
HKD3_k127_4172472_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 292.0
HKD3_k127_4172472_18 Sulfite exporter TauE/SafE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003119 275.0
HKD3_k127_4172472_19 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000001439 265.0
HKD3_k127_4172472_2 COG0457 FOG TPR repeat - - - 8.353e-237 754.0
HKD3_k127_4172472_20 Protein of unknown function (DUF3313) - - - 0.0000000000000000000000000000000000000000000000000000000003185 210.0
HKD3_k127_4172472_21 PFAM Bacterial regulatory helix-turn-helix proteins, AraC family - - - 0.0000000000000000000000000000000000000000000000000000000007196 218.0
HKD3_k127_4172472_22 Protein of unknown function, DUF481 - - - 0.000000000000000000000000000000000000000000000000000000008596 213.0
HKD3_k127_4172472_23 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001283 216.0
HKD3_k127_4172472_24 Pectinacetylesterase - - - 0.00000000000000000000000000000000000000000000000001909 199.0
HKD3_k127_4172472_25 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000056 175.0
HKD3_k127_4172472_26 - - - - 0.000000000000000000000000000000000000000000001191 174.0
HKD3_k127_4172472_27 VIT family - - - 0.000000000000000000000000000000000000000000002627 174.0
HKD3_k127_4172472_28 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000001168 148.0
HKD3_k127_4172472_29 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000001027 140.0
HKD3_k127_4172472_3 protein conserved in bacteria - - - 4.799e-205 657.0
HKD3_k127_4172472_30 Ion transport 2 domain protein - - - 0.00000000000000000000002124 110.0
HKD3_k127_4172472_31 CpeT/CpcT family (DUF1001) - - - 0.000000000000000000002032 106.0
HKD3_k127_4172472_32 Domain of unknown function (DUF1330) - - - 0.00000000000005652 83.0
HKD3_k127_4172472_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11745,K11747 - - 1.598e-200 643.0
HKD3_k127_4172472_5 pyruvate flavodoxin ferredoxin oxidoreductase K00169 - 1.2.7.1 2.332e-199 628.0
HKD3_k127_4172472_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 537.0
HKD3_k127_4172472_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 494.0
HKD3_k127_4172472_8 Sodium/calcium exchanger protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 474.0
HKD3_k127_4172472_9 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 474.0
HKD3_k127_4290187_0 Amidohydrolase family K01466 - 3.5.2.5 3.592e-213 683.0
HKD3_k127_4290187_1 PFAM Type II secretion system protein E K02454 - - 1.101e-204 661.0
HKD3_k127_4290187_10 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 319.0
HKD3_k127_4290187_11 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 314.0
HKD3_k127_4290187_12 PFAM Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 302.0
HKD3_k127_4290187_13 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002472 247.0
HKD3_k127_4290187_14 Peroxiredoxin K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000002464 224.0
HKD3_k127_4290187_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000003354 223.0
HKD3_k127_4290187_16 Type II secretion system (T2SS), protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000006488 207.0
HKD3_k127_4290187_17 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000001407 199.0
HKD3_k127_4290187_18 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000003049 172.0
HKD3_k127_4290187_19 Protein of unknown function DUF45 K07043 - - 0.00000000000000000000000000000000000000002192 162.0
HKD3_k127_4290187_2 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006788 554.0
HKD3_k127_4290187_20 COG5424 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C K06137 - 1.3.3.11 0.00000000000000000000000000000000000000003297 164.0
HKD3_k127_4290187_21 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000003694 147.0
HKD3_k127_4290187_22 OmpA family - - - 0.00000000000000000000000000002451 137.0
HKD3_k127_4290187_23 - - - - 0.000000000000000000000002735 117.0
HKD3_k127_4290187_24 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000176 99.0
HKD3_k127_4290187_25 COG3156 Type II secretory pathway, component PulK K02460 - - 0.00000000000000000177 98.0
HKD3_k127_4290187_26 - - - - 0.0000000000001114 83.0
HKD3_k127_4290187_28 Prokaryotic N-terminal methylation motif - - - 0.0000000003047 66.0
HKD3_k127_4290187_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009974 487.0
HKD3_k127_4290187_4 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 398.0
HKD3_k127_4290187_5 COG1459 Type II secretory pathway, component PulF K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008838 390.0
HKD3_k127_4290187_6 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 364.0
HKD3_k127_4290187_7 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 357.0
HKD3_k127_4290187_8 NADP-dependent oxidoreductase K00001,K07119 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 353.0
HKD3_k127_4290187_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 336.0
HKD3_k127_435167_0 aconitate hydratase K01681,K20455 - 4.2.1.117,4.2.1.3 0.0 1557.0
HKD3_k127_435167_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.222e-279 864.0
HKD3_k127_435167_10 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005822 277.0
HKD3_k127_435167_11 cytochrome - - - 0.000000000000000000000000000000000000000000000000000008384 200.0
HKD3_k127_435167_12 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000000002286 183.0
HKD3_k127_435167_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000005498 165.0
HKD3_k127_435167_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000007523 148.0
HKD3_k127_435167_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000005034 138.0
HKD3_k127_435167_16 MaoC like domain - - - 0.000000000000000000009794 105.0
HKD3_k127_435167_17 Lipid A 3-O-deacylase (PagL) - - - 0.000000000006001 74.0
HKD3_k127_435167_18 COG3312 F0F1-type ATP synthase, subunit I K02116 GO:0003674,GO:0003824,GO:0005215,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000001651 56.0
HKD3_k127_435167_2 PrpF protein K09788 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0071704,GO:0072329,GO:1901575 - 1.087e-223 698.0
HKD3_k127_435167_3 Belongs to the citrate synthase family K01659 - 2.3.3.5 4.069e-217 677.0
HKD3_k127_435167_4 2-methylcitrate dehydratase K01720 - 4.2.1.79 2.759e-208 659.0
HKD3_k127_435167_5 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 434.0
HKD3_k127_435167_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 367.0
HKD3_k127_435167_7 chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 348.0
HKD3_k127_435167_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 344.0
HKD3_k127_435167_9 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 337.0
HKD3_k127_4379747_0 Histidine kinase - - - 0.0 1080.0
HKD3_k127_4379747_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1041.0
HKD3_k127_4379747_10 Amino acid permease K11735 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 464.0
HKD3_k127_4379747_11 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 393.0
HKD3_k127_4379747_12 TIGRFAM TonB-dependent heme hemoglobin receptor family protein K02014,K16087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 389.0
HKD3_k127_4379747_13 FAD linked oxidase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 379.0
HKD3_k127_4379747_14 Adenylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 374.0
HKD3_k127_4379747_15 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005718 368.0
HKD3_k127_4379747_16 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 361.0
HKD3_k127_4379747_17 Cytokinin riboside 5'-monophosphate phosphoribohydrolase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 329.0
HKD3_k127_4379747_18 Belongs to the long-chain O-acyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 308.0
HKD3_k127_4379747_19 NADPH quinone reductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005439 284.0
HKD3_k127_4379747_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.4e-323 1003.0
HKD3_k127_4379747_20 glutathione s-transferase K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001269 282.0
HKD3_k127_4379747_21 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 272.0
HKD3_k127_4379747_22 dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006709 262.0
HKD3_k127_4379747_23 Acetyl-coenzyme A transporter 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000001855 251.0
HKD3_k127_4379747_24 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000001938 235.0
HKD3_k127_4379747_25 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000007652 241.0
HKD3_k127_4379747_26 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000000000000000000000005288 201.0
HKD3_k127_4379747_27 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000009736 205.0
HKD3_k127_4379747_28 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000001512 160.0
HKD3_k127_4379747_29 Protein of unknown function, DUF485 - - - 0.0000000000000000000000000000000000001032 143.0
HKD3_k127_4379747_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 2.327e-288 897.0
HKD3_k127_4379747_30 DNA polymerase III K02342 - 2.7.7.7 0.0000000000000000000000000000000000001141 150.0
HKD3_k127_4379747_32 Glyoxalase-like domain - - - 0.00000000000000000000000312 112.0
HKD3_k127_4379747_33 transcriptional regulator - - - 0.00000000000000000008134 105.0
HKD3_k127_4379747_34 Domain of unknown function (DUF4440) - - - 0.000000000008372 72.0
HKD3_k127_4379747_4 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 526.0
HKD3_k127_4379747_5 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 526.0
HKD3_k127_4379747_6 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 528.0
HKD3_k127_4379747_7 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 511.0
HKD3_k127_4379747_8 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 468.0
HKD3_k127_4379747_9 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 470.0
HKD3_k127_4380134_0 PFAM Type II secretion system protein E K02454 - - 1.136e-203 645.0
HKD3_k127_4380134_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 569.0
HKD3_k127_4380134_10 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 321.0
HKD3_k127_4380134_11 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002665 284.0
HKD3_k127_4380134_12 phosphatase K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000544 274.0
HKD3_k127_4380134_13 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000142 184.0
HKD3_k127_4380134_14 Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000004901 173.0
HKD3_k127_4380134_15 Type II secretion system protein C - - - 0.0000000000000000000000000000000000000000004874 171.0
HKD3_k127_4380134_16 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000002846 158.0
HKD3_k127_4380134_17 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000003715 160.0
HKD3_k127_4380134_18 Belongs to the HSP15 family K04762 - - 0.0000000000000000000000000000003123 127.0
HKD3_k127_4380134_19 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000003347 112.0
HKD3_k127_4380134_2 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 563.0
HKD3_k127_4380134_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 561.0
HKD3_k127_4380134_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 546.0
HKD3_k127_4380134_5 General Secretion Pathway protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 550.0
HKD3_k127_4380134_6 Belongs to the ClpA ClpB family K03694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 471.0
HKD3_k127_4380134_7 signal peptide peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 484.0
HKD3_k127_4380134_8 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 475.0
HKD3_k127_4380134_9 General secretion pathway protein K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 418.0
HKD3_k127_450972_0 Malate synthase K01638 - 2.3.3.9 2.009e-244 765.0
HKD3_k127_450972_1 Isocitrate lyase K01637 - 4.1.3.1 2.242e-228 713.0
HKD3_k127_450972_2 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 606.0
HKD3_k127_450972_3 saccharopine dehydrogenase activity K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 451.0
HKD3_k127_450972_4 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000001189 242.0
HKD3_k127_4556498_0 AAA-like domain - - - 3.68e-246 784.0
HKD3_k127_4556498_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 490.0
HKD3_k127_4556498_2 TIGRFAM sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 444.0
HKD3_k127_4556498_3 ATPase activity K02045 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 409.0
HKD3_k127_4556498_4 TIGRFAM sulfate ABC transporter, permease protein CysW, sulfate ABC transporter, permease protein K02047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 376.0
HKD3_k127_4556498_5 Sulfate ABC transporter inner membrane subunit CysT K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 366.0
HKD3_k127_4556498_6 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 317.0
HKD3_k127_4556498_7 - - - - 0.00000000000000000000000000000000000001654 153.0
HKD3_k127_4556498_8 Two component transcriptional regulator, winged helix family - - - 0.000000000000000000000000000000000002728 150.0
HKD3_k127_4556498_9 Protein of unknown function VcgC/VcgE (DUF2780) - - - 0.000000001268 64.0
HKD3_k127_4559974_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 575.0
HKD3_k127_4559974_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 502.0
HKD3_k127_4559974_2 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 418.0
HKD3_k127_4559974_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000001417 205.0
HKD3_k127_4559974_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K12132 - 2.7.11.1 0.0000000000000000000000000001379 132.0
HKD3_k127_4570118_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1107.0
HKD3_k127_4570118_1 Putative serine dehydratase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004013 249.0
HKD3_k127_4570118_2 Protoporphyrinogen oxidase K00230 GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000002643 243.0
HKD3_k127_4570118_3 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.000000000000000000000000000000000000000000000006419 189.0
HKD3_k127_4570118_4 Adenylate cyclase - - - 0.00000000000000000000000000000000000000000000003174 179.0
HKD3_k127_4570118_5 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000000000204 157.0
HKD3_k127_476019_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 3.696e-234 736.0
HKD3_k127_476019_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 536.0
HKD3_k127_476019_10 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000001382 231.0
HKD3_k127_476019_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000000000005813 184.0
HKD3_k127_476019_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 541.0
HKD3_k127_476019_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 513.0
HKD3_k127_476019_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 450.0
HKD3_k127_476019_5 Type II secretory pathway, component HofQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 342.0
HKD3_k127_476019_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 338.0
HKD3_k127_476019_7 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 295.0
HKD3_k127_476019_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004778 278.0
HKD3_k127_476019_9 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009686 278.0
HKD3_k127_4848059_0 COG0457 FOG TPR repeat - - - 2.375e-269 844.0
HKD3_k127_4848059_1 COG1228 Imidazolonepropionase and related amidohydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 409.0
HKD3_k127_4848059_2 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000000000000000000000000000000000000000000000000000002895 199.0
HKD3_k127_4865460_0 elongation factor G K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 478.0
HKD3_k127_4865460_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 400.0
HKD3_k127_4865460_2 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001071 271.0
HKD3_k127_487641_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955 - 2.7.1.25,2.7.7.4 1.428e-318 985.0
HKD3_k127_487641_1 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007871 566.0
HKD3_k127_487641_2 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 522.0
HKD3_k127_487641_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000448 340.0
HKD3_k127_487641_4 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000502 267.0
HKD3_k127_487641_5 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000001665 230.0
HKD3_k127_4895025_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1051.0
HKD3_k127_4895025_1 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005979,GO:0006109,GO:0006139,GO:0006417,GO:0006446,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010675,GO:0010677,GO:0010906,GO:0010962,GO:0016070,GO:0016071,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032881,GO:0032885,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0043255,GO:0043467,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0045719,GO:0045912,GO:0045947,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0062012,GO:0065007,GO:0070873,GO:0070874,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.0000000000000000000000003319 109.0
HKD3_k127_4895025_2 Recombinase zinc beta ribbon domain - - - 0.0001992 49.0
HKD3_k127_4975243_0 Methionine synthase K00548 - 2.1.1.13 0.0 1676.0
HKD3_k127_4975243_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 5.075e-267 845.0
HKD3_k127_4975243_10 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 398.0
HKD3_k127_4975243_11 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009806 371.0
HKD3_k127_4975243_12 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 322.0
HKD3_k127_4975243_13 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000929 287.0
HKD3_k127_4975243_14 Oxidoreductase FAD-binding domain K18225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001645 274.0
HKD3_k127_4975243_15 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002622 278.0
HKD3_k127_4975243_16 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000005156 253.0
HKD3_k127_4975243_17 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000005466 248.0
HKD3_k127_4975243_18 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000002096 234.0
HKD3_k127_4975243_19 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000004025 215.0
HKD3_k127_4975243_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.956e-238 768.0
HKD3_k127_4975243_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000001203 211.0
HKD3_k127_4975243_21 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000000000004741 192.0
HKD3_k127_4975243_22 DNA primase - - - 0.0000000000000000000000000000001179 130.0
HKD3_k127_4975243_23 - - - - 0.000000000000000000000001371 108.0
HKD3_k127_4975243_24 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006807,GO:0008104,GO:0008150,GO:0008152,GO:0008289,GO:0009279,GO:0010876,GO:0016020,GO:0019538,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0033218,GO:0034613,GO:0042157,GO:0042277,GO:0043170,GO:0044238,GO:0044462,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0051668,GO:0070727,GO:0071704,GO:0071723,GO:0071944,GO:0072657,GO:1901564 - 0.000000000000000000000005785 110.0
HKD3_k127_4975243_25 DNA excision K07733 - - 0.0000000000002956 71.0
HKD3_k127_4975243_26 - - - - 0.0000001476 60.0
HKD3_k127_4975243_27 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.00003748 50.0
HKD3_k127_4975243_28 - - - - 0.0001189 51.0
HKD3_k127_4975243_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.46e-212 668.0
HKD3_k127_4975243_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 537.0
HKD3_k127_4975243_5 PCRF K02835 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008863 497.0
HKD3_k127_4975243_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 485.0
HKD3_k127_4975243_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007664 428.0
HKD3_k127_4975243_8 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 416.0
HKD3_k127_4975243_9 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 419.0
HKD3_k127_4977229_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.646e-210 670.0
HKD3_k127_4977229_1 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002003 275.0
HKD3_k127_4977229_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0031224,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000007258 208.0
HKD3_k127_4977229_3 PFAM isocitrate lyase and phosphorylmutase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000001654 183.0
HKD3_k127_5006934_0 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 603.0
HKD3_k127_5027570_0 Efflux pump membrane transporter K03296,K18138 - - 0.0 1086.0
HKD3_k127_5027570_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.611e-208 661.0
HKD3_k127_5027570_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 376.0
HKD3_k127_5032517_0 small GTP-binding protein K02355 - - 4.151e-291 913.0
HKD3_k127_5032517_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 409.0
HKD3_k127_5032517_10 Protein of unknown function (DUF541) K09797 - - 0.000000000000000000000000000000000000000000335 168.0
HKD3_k127_5032517_11 PFAM OsmC family protein K04063 - - 0.0000000000000000000000000000000000000000003892 162.0
HKD3_k127_5032517_12 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000001731 174.0
HKD3_k127_5032517_13 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000005762 140.0
HKD3_k127_5032517_14 - - - - 0.000000000000000000000000000001022 134.0
HKD3_k127_5032517_15 Fic/DOC family K07341 - - 0.0000000000000000000000003388 109.0
HKD3_k127_5032517_16 Addiction module antidote - - - 0.000000000000000000004511 94.0
HKD3_k127_5032517_2 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 388.0
HKD3_k127_5032517_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 - 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 371.0
HKD3_k127_5032517_4 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 334.0
HKD3_k127_5032517_5 alpha/beta hydrolase fold K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 324.0
HKD3_k127_5032517_6 Acyl-CoA dehydrogenase K00252 - 1.3.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 299.0
HKD3_k127_5032517_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006 269.0
HKD3_k127_5032517_8 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000387 234.0
HKD3_k127_5032517_9 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000003362 193.0
HKD3_k127_5041508_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1229.0
HKD3_k127_5041508_1 TIGRFAM ATP-dependent helicase HrpA K03578 - 3.6.4.13 0.0 1097.0
HKD3_k127_5041508_10 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 413.0
HKD3_k127_5041508_11 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 328.0
HKD3_k127_5041508_12 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 308.0
HKD3_k127_5041508_13 MazG nucleotide pyrophosphohydrolase domain K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 306.0
HKD3_k127_5041508_14 hydrolase activity, acting on ester bonds K01055 - 3.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 313.0
HKD3_k127_5041508_15 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 291.0
HKD3_k127_5041508_16 peptidase M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000675 280.0
HKD3_k127_5041508_17 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008748 267.0
HKD3_k127_5041508_18 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000000000000000001611 228.0
HKD3_k127_5041508_19 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.00000000000000000000000000000000000000000000000000000005489 204.0
HKD3_k127_5041508_2 Aldehyde dehydrogenase family K00128 - 1.2.1.3 1.731e-217 685.0
HKD3_k127_5041508_20 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000007253 186.0
HKD3_k127_5041508_21 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000000463 186.0
HKD3_k127_5041508_22 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000002352 184.0
HKD3_k127_5041508_23 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000004144 174.0
HKD3_k127_5041508_24 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000003225 142.0
HKD3_k127_5041508_25 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000127 125.0
HKD3_k127_5041508_26 protein acetylation - - - 0.000000000000000000000002577 109.0
HKD3_k127_5041508_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 597.0
HKD3_k127_5041508_4 Aldehyde dehydrogenase family K00151 - 1.2.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 561.0
HKD3_k127_5041508_5 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 554.0
HKD3_k127_5041508_6 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 536.0
HKD3_k127_5041508_7 Membrane-bound serine protease (ClpP class) K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 474.0
HKD3_k127_5041508_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 468.0
HKD3_k127_5041508_9 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 451.0
HKD3_k127_5055076_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1176.0
HKD3_k127_5055076_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 564.0
HKD3_k127_5055076_2 SMART AAA ATPase K06923 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 361.0
HKD3_k127_5055076_3 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002208 292.0
HKD3_k127_5055076_4 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000001665 234.0
HKD3_k127_5055076_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000001674 92.0
HKD3_k127_5065857_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 566.0
HKD3_k127_5083364_0 Carbamoyltransferase K00612 - - 5.88e-250 786.0
HKD3_k127_5083364_1 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 553.0
HKD3_k127_5083364_2 Alpha-amylase domain K01176 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007202 543.0
HKD3_k127_5083364_3 Bacterial extracellular solute-binding protein K15770 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 501.0
HKD3_k127_5083364_4 Belongs to the ABC transporter superfamily K10111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 473.0
HKD3_k127_5083364_5 maltose-transporting ATPase activity K15772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 453.0
HKD3_k127_5083364_6 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 376.0
HKD3_k127_5083364_7 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 334.0
HKD3_k127_5083364_8 - - - - 0.00000000000000002605 86.0
HKD3_k127_5083364_9 - - - - 0.000000000000001115 77.0
HKD3_k127_5087331_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 2.71e-198 628.0
HKD3_k127_5087331_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 1.557e-195 619.0
HKD3_k127_5087331_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.771e-194 616.0
HKD3_k127_5087331_3 COG0471 Di- and tricarboxylate transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 563.0
HKD3_k127_5087331_4 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000431 190.0
HKD3_k127_5114156_0 Nitrite reductase K15864 - 1.7.2.1,1.7.99.1 1.671e-257 807.0
HKD3_k127_5114156_1 Protein of unknown function (DUF3604) - - - 4.024e-240 764.0
HKD3_k127_5114156_2 Protein of unknown function (DUF3604) - - - 1.408e-226 720.0
HKD3_k127_5114156_3 Protein of unknown function (DUF3604) - - - 2.374e-222 708.0
HKD3_k127_5114156_4 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 6.539e-195 635.0
HKD3_k127_5114156_5 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 426.0
HKD3_k127_5114156_6 helix_turn_helix, cAMP Regulatory protein K21563 - - 0.000000000000000000000000000000000000000000000364 175.0
HKD3_k127_5114156_7 Transcriptional regulator - - - 0.000000000000000000000008559 112.0
HKD3_k127_5197815_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 3.827e-208 658.0
HKD3_k127_5197815_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 564.0
HKD3_k127_5197815_10 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001951 271.0
HKD3_k127_5197815_11 Protein conserved in bacteria K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003869 282.0
HKD3_k127_5197815_12 dithiol-disulfide isomerase involved in polyketide biosynthesis K01829 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 253.0
HKD3_k127_5197815_13 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002913 258.0
HKD3_k127_5197815_14 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000002349 228.0
HKD3_k127_5197815_15 Uracil DNA glycosylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000008474 223.0
HKD3_k127_5197815_16 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000000000000132 201.0
HKD3_k127_5197815_17 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000002395 198.0
HKD3_k127_5197815_18 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000003282 192.0
HKD3_k127_5197815_19 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000004802 195.0
HKD3_k127_5197815_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 461.0
HKD3_k127_5197815_20 nuclease - - - 0.00000000000000000000000000000000000003673 156.0
HKD3_k127_5197815_21 MazG-like family - - - 0.00000000000000000000000000000000000008184 153.0
HKD3_k127_5197815_22 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000001149 144.0
HKD3_k127_5197815_23 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000005856 114.0
HKD3_k127_5197815_24 - - - - 0.000000000000000000002503 106.0
HKD3_k127_5197815_25 Belongs to the UPF0270 family K09898 - - 0.0000000000002065 76.0
HKD3_k127_5197815_26 - - - - 0.0000000000003489 76.0
HKD3_k127_5197815_27 - - - - 0.000000004104 62.0
HKD3_k127_5197815_28 OmpA-like transmembrane domain - - - 0.000003005 57.0
HKD3_k127_5197815_29 - - - - 0.000004162 58.0
HKD3_k127_5197815_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 398.0
HKD3_k127_5197815_30 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.00006328 55.0
HKD3_k127_5197815_4 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 355.0
HKD3_k127_5197815_5 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000983 308.0
HKD3_k127_5197815_6 epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006963 293.0
HKD3_k127_5197815_7 Belongs to the glutathione peroxidase family K00432 GO:0003674,GO:0003824,GO:0004601,GO:0004602,GO:0005575,GO:0005623,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0033194,GO:0042221,GO:0042597,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007153 279.0
HKD3_k127_5197815_8 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007473 276.0
HKD3_k127_5197815_9 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000485 280.0
HKD3_k127_5258809_0 COG1506 Dipeptidyl aminopeptidases acylaminoacyl-peptidases - - - 4.202e-249 788.0
HKD3_k127_5258809_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.218e-213 667.0
HKD3_k127_5258809_10 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000005752 244.0
HKD3_k127_5258809_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000002353 196.0
HKD3_k127_5258809_12 Outer membrane protein W K07275 - - 0.00000000000000000000000000000000000000000003434 169.0
HKD3_k127_5258809_13 membrane - - - 0.000000000000000000000000000000000000006295 149.0
HKD3_k127_5258809_14 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000156 156.0
HKD3_k127_5258809_15 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000002566 134.0
HKD3_k127_5258809_16 ECF sigma factor K03088 - - 0.0000000000000000001877 95.0
HKD3_k127_5258809_17 Activator of hsp90 atpase 1 family protein - - - 0.000007682 55.0
HKD3_k127_5258809_2 peptidase K01284 - 3.4.15.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 549.0
HKD3_k127_5258809_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004929 479.0
HKD3_k127_5258809_4 L,D-transpeptidase catalytic domain K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 488.0
HKD3_k127_5258809_5 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 452.0
HKD3_k127_5258809_6 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 400.0
HKD3_k127_5258809_7 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 314.0
HKD3_k127_5258809_8 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 293.0
HKD3_k127_5258809_9 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002693 250.0
HKD3_k127_5259710_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 3.603e-240 754.0
HKD3_k127_5259710_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 314.0
HKD3_k127_5259710_2 Protein of unknown function (DUF1249) K09920 - - 0.00000000000000000001346 104.0
HKD3_k127_5413176_0 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 522.0
HKD3_k127_5413176_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 313.0
HKD3_k127_547806_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1349.0
HKD3_k127_547806_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 7.41e-297 924.0
HKD3_k127_547806_10 Part of a membrane complex involved in electron transport K03615 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 406.0
HKD3_k127_547806_11 PFAM Cytochrome P450 K14338 - 1.14.14.1,1.6.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 385.0
HKD3_k127_547806_12 Cytosol aminopeptidase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 380.0
HKD3_k127_547806_13 Belongs to the UPF0276 family K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 366.0
HKD3_k127_547806_14 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 393.0
HKD3_k127_547806_15 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 349.0
HKD3_k127_547806_16 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 333.0
HKD3_k127_547806_17 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 298.0
HKD3_k127_547806_18 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006715 312.0
HKD3_k127_547806_19 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 GO:0000287,GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004540,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008408,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0031123,GO:0034470,GO:0034641,GO:0034660,GO:0042780,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 288.0
HKD3_k127_547806_2 PFAM biotin lipoyl attachment domain-containing protein K00382 - 1.8.1.4 1.531e-233 737.0
HKD3_k127_547806_20 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001659 296.0
HKD3_k127_547806_21 Putative DNA-binding domain K09929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002523 262.0
HKD3_k127_547806_22 Part of a membrane complex involved in electron transport K03617 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002437 245.0
HKD3_k127_547806_23 Urate oxidase N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001114 244.0
HKD3_k127_547806_24 PFAM Sulfotransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000001578 227.0
HKD3_k127_547806_25 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000000000000000000000000000000000000000002349 225.0
HKD3_k127_547806_26 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000003411 215.0
HKD3_k127_547806_27 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000001949 212.0
HKD3_k127_547806_28 Domain of unknown function (DUF1841) - - - 0.00000000000000000000000000000000000000000000000002225 182.0
HKD3_k127_547806_29 Domain of unknown function (DUF374) - - - 0.00000000000000000000000000000000000000000000000004207 187.0
HKD3_k127_547806_3 Diguanylate cyclase - - - 8.022e-204 665.0
HKD3_k127_547806_30 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000007396 163.0
HKD3_k127_547806_31 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000003102 149.0
HKD3_k127_547806_32 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000003469 146.0
HKD3_k127_547806_33 belongs to the Fur family K09826 - - 0.000000000000000000000000000000001908 136.0
HKD3_k127_547806_34 Type II transport protein GspH K08084 - - 0.000000000000000000000000921 111.0
HKD3_k127_547806_35 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000007244 91.0
HKD3_k127_547806_36 Type IV Pilus-assembly protein W K02672 - - 0.00000000000007306 84.0
HKD3_k127_547806_37 TIGRFAM Pilus modification type IV, PilV K02671 - - 0.000000000001039 75.0
HKD3_k127_547806_38 Type II transport protein GspH K08084 - - 0.00000000004033 72.0
HKD3_k127_547806_39 Fe-S protein K06938 - - 0.00000004277 57.0
HKD3_k127_547806_4 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K13614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 604.0
HKD3_k127_547806_40 Type IV pilus assembly protein PilX C-term K02673 - - 0.000006779 57.0
HKD3_k127_547806_41 lysine biosynthetic process via aminoadipic acid K00997,K06133 - 2.7.8.7 0.000009469 56.0
HKD3_k127_547806_5 PFAM Type II secretion system protein E - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 498.0
HKD3_k127_547806_6 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 471.0
HKD3_k127_547806_7 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004626 470.0
HKD3_k127_547806_8 PFAM Type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 472.0
HKD3_k127_547806_9 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 415.0
HKD3_k127_5490158_0 Prolyl oligopeptidase family - - - 5.434e-242 768.0
HKD3_k127_5490158_1 leucine-zipper of insertion element IS481 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 443.0
HKD3_k127_5490158_2 Biopolymer transporter ExbB K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000004418 242.0
HKD3_k127_5490158_3 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000001484 149.0
HKD3_k127_5490158_4 Protein of unknown function (DUF1232) - - - 0.0000000000000000000000000000002467 130.0
HKD3_k127_5490158_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 GO:0000988,GO:0000990,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006352,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016987,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043254,GO:0044087,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2000142,GO:2001141 - 0.00000000000000000001138 91.0
HKD3_k127_5490158_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000003956 99.0
HKD3_k127_5490158_7 - - - - 0.00000000003908 73.0
HKD3_k127_5518509_0 Oxidoreductase - - - 2.08e-290 904.0
HKD3_k127_5518509_1 receptor - - - 1.336e-244 773.0
HKD3_k127_5518509_2 Glycine cleavage T-protein C-terminal barrel domain - - - 1.2e-219 686.0
HKD3_k127_5518509_3 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 445.0
HKD3_k127_5668869_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain - - - 1.178e-265 836.0
HKD3_k127_5668869_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 572.0
HKD3_k127_5668869_10 ethanolamine kinase activity K07251 - 2.7.1.89 0.0000000000000000000000005842 115.0
HKD3_k127_5668869_11 YKOF-related Family - - - 0.000000000000000000008716 100.0
HKD3_k127_5668869_12 glutamate dehydrogenase K15371 - 1.4.1.2 0.000000000001423 71.0
HKD3_k127_5668869_2 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 439.0
HKD3_k127_5668869_3 phosphoglycerate mutase activity K01834 GO:0003674,GO:0003824,GO:0004619,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006109,GO:0006139,GO:0006140,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009894,GO:0009987,GO:0010675,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0018130,GO:0019219,GO:0019220,GO:0019222,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0031323,GO:0031329,GO:0032787,GO:0034248,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0043455,GO:0043456,GO:0043470,GO:0043471,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046538,GO:0046700,GO:0046939,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051186,GO:0051188,GO:0051193,GO:0051196,GO:0055086,GO:0060255,GO:0062012,GO:0065007,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902031 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 370.0
HKD3_k127_5668869_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 335.0
HKD3_k127_5668869_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000008678 242.0
HKD3_k127_5668869_6 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001926 231.0
HKD3_k127_5668869_7 COG3201 Nicotinamide mononucleotide transporter K03811 - - 0.0000000000000000000000000000000000000000000000424 182.0
HKD3_k127_5668869_8 TonB-dependent receptor plug K02014 - - 0.00000000000000000000000000000000000004064 146.0
HKD3_k127_5668869_9 ferredoxin K04755 - - 0.00000000000000000000000000002556 121.0
HKD3_k127_5697654_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1109.0
HKD3_k127_5697654_1 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 565.0
HKD3_k127_5697654_10 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000004907 281.0
HKD3_k127_5697654_11 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000003209 256.0
HKD3_k127_5697654_12 Major facilitator K03292 - - 0.00000000000000000000000000000000000000000000000000001368 206.0
HKD3_k127_5697654_13 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000007313 183.0
HKD3_k127_5697654_14 Belongs to the CinA family K03743 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 0.0000000000000000000000000000000000000000000064 171.0
HKD3_k127_5697654_15 Domain of unknown function (DUF4136) - - - 0.000000000000000000000000000000000000000001059 164.0
HKD3_k127_5697654_16 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.000000000000000000000000000000000001022 151.0
HKD3_k127_5697654_17 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000003393 152.0
HKD3_k127_5697654_18 Modulates RecA activity K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.00000000000000000000000000000009084 132.0
HKD3_k127_5697654_19 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000002839 132.0
HKD3_k127_5697654_2 Belongs to the xylose isomerase family K01805 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009045,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019323,GO:0042732,GO:0042843,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046365,GO:0071704,GO:1901575 5.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 557.0
HKD3_k127_5697654_20 - - - - 0.0000000000000002932 90.0
HKD3_k127_5697654_21 - - - - 0.00000000000007142 80.0
HKD3_k127_5697654_22 Methylmuconolactone methyl-isomerase - - - 0.00000002261 63.0
HKD3_k127_5697654_23 Methylmuconolactone methyl-isomerase - - - 0.0001319 53.0
HKD3_k127_5697654_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 551.0
HKD3_k127_5697654_4 Alpha-amylase domain K01187 - 3.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 542.0
HKD3_k127_5697654_5 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 491.0
HKD3_k127_5697654_6 COG3119 Arylsulfatase A and related enzymes K01138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 460.0
HKD3_k127_5697654_7 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 334.0
HKD3_k127_5697654_8 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 301.0
HKD3_k127_5697654_9 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005118 284.0
HKD3_k127_5856103_0 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 2.418e-197 624.0
HKD3_k127_5856103_1 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005884 570.0
HKD3_k127_5856103_10 Oligoendopeptidase f K01283 - 3.4.15.1 0.0000006213 62.0
HKD3_k127_5856103_11 PFAM NHL repeat containing protein - - - 0.000009926 53.0
HKD3_k127_5856103_2 Kef-type K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 546.0
HKD3_k127_5856103_3 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 499.0
HKD3_k127_5856103_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 290.0
HKD3_k127_5856103_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000001958 239.0
HKD3_k127_5856103_6 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000000000000000000000000001203 224.0
HKD3_k127_5856103_7 - - - - 0.0000000000000000000000000000000000000000000001251 174.0
HKD3_k127_5856103_8 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000003122 137.0
HKD3_k127_5856103_9 Protein of unknown function (DUF2892) - - - 0.000000000000000000000001855 104.0
HKD3_k127_6086220_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 4.17e-221 695.0
HKD3_k127_6086220_1 COG2015 Alkyl sulfatase and related hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 381.0
HKD3_k127_6086220_2 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000004477 203.0
HKD3_k127_6086220_3 Protein of unknown function (DUF861) K06995 - - 0.000000000000000000000000000000006562 141.0
HKD3_k127_6086220_4 4Fe-4S dicluster domain - - - 0.0000000005121 64.0
HKD3_k127_6096598_0 penicillin-binding protein K05366 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0008955,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 2.4.1.129,3.4.16.4 3.377e-226 725.0
HKD3_k127_6096598_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 5.497e-200 631.0
HKD3_k127_6096598_10 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000007594 119.0
HKD3_k127_6096598_2 Type II secretory pathway, component HofQ K02666 - - 5.811e-194 628.0
HKD3_k127_6096598_3 Zn-dependent protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 426.0
HKD3_k127_6096598_4 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 370.0
HKD3_k127_6096598_5 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000005477 218.0
HKD3_k127_6096598_6 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000000000003362 186.0
HKD3_k127_6096598_7 PFAM Fimbrial assembly K02663 - - 0.00000000000000000000000000000000000000000000009322 176.0
HKD3_k127_6096598_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000000000001906 165.0
HKD3_k127_6096598_9 pilus assembly protein pilp K02665 - - 0.0000000000000000000000000000000000000184 161.0
HKD3_k127_6265721_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.659e-196 619.0
HKD3_k127_6265721_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008233 621.0
HKD3_k127_6265721_10 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 313.0
HKD3_k127_6265721_11 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 312.0
HKD3_k127_6265721_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000312 283.0
HKD3_k127_6265721_13 Cytochrome C1 family K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009541 275.0
HKD3_k127_6265721_14 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
HKD3_k127_6265721_15 Stringent starvation protein A K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000001676 230.0
HKD3_k127_6265721_16 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000000000000002599 199.0
HKD3_k127_6265721_17 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000002995 199.0
HKD3_k127_6265721_18 Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a) K07121 GO:0000270,GO:0003674,GO:0005575,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030203,GO:0030234,GO:0030312,GO:0030313,GO:0031241,GO:0031975,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044425,GO:0044462,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098772,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000001399 211.0
HKD3_k127_6265721_19 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000001807 172.0
HKD3_k127_6265721_2 protein conserved in bacteria K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 578.0
HKD3_k127_6265721_20 stringent starvation protein b K03600 - - 0.0000000000000000000000000000000001736 145.0
HKD3_k127_6265721_21 - - - - 0.0000000000000000000000000000001949 128.0
HKD3_k127_6265721_22 Sigma 54 modulation protein K05808 - - 0.000000000000000000000000000442 131.0
HKD3_k127_6265721_23 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000001004 127.0
HKD3_k127_6265721_24 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000002117 100.0
HKD3_k127_6265721_25 Belongs to the BolA IbaG family - - - 0.0000000000000000007155 90.0
HKD3_k127_6265721_26 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000001895 63.0
HKD3_k127_6265721_27 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA K11719 - - 0.0000007275 61.0
HKD3_k127_6265721_3 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006812 516.0
HKD3_k127_6265721_4 ATPase associated with various cellular activities, AAA_5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 462.0
HKD3_k127_6265721_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 443.0
HKD3_k127_6265721_6 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 428.0
HKD3_k127_6265721_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 346.0
HKD3_k127_6265721_8 ABC transporter, ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 337.0
HKD3_k127_6265721_9 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 327.0
HKD3_k127_6286126_0 Belongs to the GPAT DAPAT family K00631 GO:0003674,GO:0003824,GO:0004366,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006629,GO:0006631,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008374,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019752,GO:0031224,GO:0031226,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009086 525.0
HKD3_k127_6286126_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 514.0
HKD3_k127_6286126_2 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 343.0
HKD3_k127_6286126_3 Inositol monophosphatase family K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008741 289.0
HKD3_k127_6286126_4 subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000007422 236.0
HKD3_k127_6286126_5 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000003795 171.0
HKD3_k127_6286126_6 RF-1 domain K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.000000000000000000000000000000000001161 144.0
HKD3_k127_6286126_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000002042 95.0
HKD3_k127_6286126_8 Protein of unknown function (DUF3301) - - - 0.00000000000000004614 84.0
HKD3_k127_6286126_9 small protein containing a coiled-coil domain - - - 0.000000000000006439 76.0
HKD3_k127_6345233_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.0 1039.0
HKD3_k127_6345233_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 1.001e-219 706.0
HKD3_k127_6345233_10 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 GO:0000287,GO:0003674,GO:0003824,GO:0003864,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016740,GO:0016741,GO:0016742,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 355.0
HKD3_k127_6345233_11 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 344.0
HKD3_k127_6345233_12 N-acetylmuramoyl-L-alanine amidase K01448 GO:0000003,GO:0000910,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0007049,GO:0008150,GO:0008745,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0019954,GO:0022402,GO:0022414,GO:0030288,GO:0030313,GO:0031975,GO:0032505,GO:0042597,GO:0043093,GO:0044464,GO:0051301,GO:0061783 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 342.0
HKD3_k127_6345233_13 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 357.0
HKD3_k127_6345233_14 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 327.0
HKD3_k127_6345233_15 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001596 280.0
HKD3_k127_6345233_16 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000164 282.0
HKD3_k127_6345233_17 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006639 278.0
HKD3_k127_6345233_18 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001506 266.0
HKD3_k127_6345233_19 (FHA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000143 221.0
HKD3_k127_6345233_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.065e-196 620.0
HKD3_k127_6345233_20 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000001626 185.0
HKD3_k127_6345233_21 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000002995 180.0
HKD3_k127_6345233_22 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000006842 175.0
HKD3_k127_6345233_23 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000004654 169.0
HKD3_k127_6345233_24 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000001278 138.0
HKD3_k127_6345233_25 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000008365 139.0
HKD3_k127_6345233_26 membrane - - - 0.00000000000000000000000000000002227 140.0
HKD3_k127_6345233_27 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 GO:0000166,GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043531,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000002998 138.0
HKD3_k127_6345233_28 to Mus musculus sphingosine-1-phosphate lyase Sgpl1 SWALL O54955 (EMBL AF036894) (568 aa) fasta scores E() K01634 - 4.1.2.27 0.00000000000000112 78.0
HKD3_k127_6345233_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 617.0
HKD3_k127_6345233_30 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000004616 76.0
HKD3_k127_6345233_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 587.0
HKD3_k127_6345233_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 529.0
HKD3_k127_6345233_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 502.0
HKD3_k127_6345233_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 476.0
HKD3_k127_6345233_8 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 449.0
HKD3_k127_6345233_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 376.0
HKD3_k127_6372038_0 glutamate synthase K00284 - 1.4.7.1 0.0 2565.0
HKD3_k127_6372038_1 COG2015 Alkyl sulfatase and related hydrolases K01138 - - 5.102e-313 970.0
HKD3_k127_6372038_10 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 577.0
HKD3_k127_6372038_11 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 599.0
HKD3_k127_6372038_12 arylsulfatase A K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 531.0
HKD3_k127_6372038_13 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004553 521.0
HKD3_k127_6372038_14 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 487.0
HKD3_k127_6372038_15 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 449.0
HKD3_k127_6372038_16 Peptidase, M16 K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 452.0
HKD3_k127_6372038_17 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000329 446.0
HKD3_k127_6372038_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 404.0
HKD3_k127_6372038_19 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 410.0
HKD3_k127_6372038_2 PQQ enzyme repeat K17760 - 1.1.9.1 2.174e-292 914.0
HKD3_k127_6372038_20 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 373.0
HKD3_k127_6372038_21 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 380.0
HKD3_k127_6372038_22 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 342.0
HKD3_k127_6372038_23 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 349.0
HKD3_k127_6372038_24 phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 327.0
HKD3_k127_6372038_25 (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 338.0
HKD3_k127_6372038_26 Type III secretion system lipoprotein chaperone (YscW) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 296.0
HKD3_k127_6372038_27 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005109 280.0
HKD3_k127_6372038_28 TIGRFAM channel protein, hemolysin III family K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001483 256.0
HKD3_k127_6372038_29 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001561 263.0
HKD3_k127_6372038_3 FtsX-like permease family K02004 - - 2.42e-276 872.0
HKD3_k127_6372038_30 esterase lipase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000001703 247.0
HKD3_k127_6372038_31 Alkylated DNA repair protein - - - 0.000000000000000000000000000000000000000000000000000000000000001212 229.0
HKD3_k127_6372038_32 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000004569 221.0
HKD3_k127_6372038_33 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000000000000001063 213.0
HKD3_k127_6372038_34 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000002606 200.0
HKD3_k127_6372038_35 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000004871 199.0
HKD3_k127_6372038_36 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000000000001066 186.0
HKD3_k127_6372038_37 Protein of unknown function (DUF3187) - - - 0.000000000000000000000000000000000000000000001642 177.0
HKD3_k127_6372038_38 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000002878 149.0
HKD3_k127_6372038_39 Protease prsW family - - - 0.00000000000000000000000000000000002922 151.0
HKD3_k127_6372038_4 TIGRFAM glutamate synthase, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.163e-268 835.0
HKD3_k127_6372038_40 PFAM sigma-70 region 2 domain protein K03088 - - 0.00000000000000000000000000000000882 134.0
HKD3_k127_6372038_41 Planctomycete cytochrome C - - - 0.00000000000000000000000000000001309 131.0
HKD3_k127_6372038_42 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000005104 125.0
HKD3_k127_6372038_43 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000008333 119.0
HKD3_k127_6372038_44 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000002992 113.0
HKD3_k127_6372038_45 SnoaL-like polyketide cyclase - - - 0.0000000000005588 74.0
HKD3_k127_6372038_46 Histidine kinase-like ATPase domain - - - 0.00000000004007 71.0
HKD3_k127_6372038_47 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000002126 64.0
HKD3_k127_6372038_48 - - - - 0.0000000002801 66.0
HKD3_k127_6372038_5 amine dehydrogenase activity - - - 6.36e-256 822.0
HKD3_k127_6372038_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.444e-236 747.0
HKD3_k127_6372038_7 GMC oxidoreductase K03333 - 1.1.3.6 7.246e-221 698.0
HKD3_k127_6372038_8 Thiamine pyrophosphate enzyme, central domain K04103 - 4.1.1.74 2.14e-204 653.0
HKD3_k127_6372038_9 Belongs to the peptidase M16 family K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006047 597.0
HKD3_k127_64244_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1022.0
HKD3_k127_64244_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0008150,GO:0008932,GO:0008933,GO:0009893,GO:0016020,GO:0016740,GO:0016757,GO:0019222,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043085,GO:0044093,GO:0044464,GO:0048518,GO:0050789,GO:0050790,GO:0051341,GO:0051353,GO:0061783,GO:0065007,GO:0065009 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 402.0
HKD3_k127_64244_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 363.0
HKD3_k127_64244_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 340.0
HKD3_k127_64244_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 297.0
HKD3_k127_64244_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000002802 240.0
HKD3_k127_64244_6 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000002383 167.0
HKD3_k127_64244_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000008252 120.0
HKD3_k127_64244_9 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.00005876 49.0
HKD3_k127_6457945_0 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 549.0
HKD3_k127_6457945_1 COG1472 Beta-glucosidase-related glycosidases K05349 - 3.2.1.21 0.00000000000000000000000000000000000000000000003024 173.0
HKD3_k127_6457945_2 Glycosyl hydrolases family 2, TIM barrel domain - - - 0.000000002293 63.0
HKD3_k127_6464021_0 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 490.0
HKD3_k127_6464021_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 451.0
HKD3_k127_6464021_2 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 356.0
HKD3_k127_6474782_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.738e-280 874.0
HKD3_k127_6474782_1 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 541.0
HKD3_k127_6474782_10 RHS Repeat - - - 0.0000000002549 66.0
HKD3_k127_6474782_2 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 558.0
HKD3_k127_6474782_3 PFAM Alcohol dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 368.0
HKD3_k127_6474782_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 362.0
HKD3_k127_6474782_5 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 328.0
HKD3_k127_6474782_6 Sulfate adenylyltransferase K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 304.0
HKD3_k127_6474782_7 cytochrome - - - 0.0000000000000000000000000000000000000000000116 170.0
HKD3_k127_6474782_8 Protein of unknown function (DUF541) - - - 0.0000000000000000000000000003231 131.0
HKD3_k127_6474782_9 Membrane protein implicated in regulation of membrane protease activity K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000005914 74.0
HKD3_k127_6663392_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 414.0
HKD3_k127_6663392_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 420.0
HKD3_k127_6663392_2 Spermidine putrescine ABC transporter substrate-binding protein K02055 GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009290,GO:0009292,GO:0009294,GO:0009987,GO:0015931,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042618,GO:0042619,GO:0044464,GO:0044764,GO:0050657,GO:0051027,GO:0051179,GO:0051234,GO:0051704,GO:0071702,GO:0071704,GO:0071705,GO:0098657,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000001856 223.0
HKD3_k127_6663392_3 Sugar (and other) transporter K07552 - - 0.0000000000000000000000000000000000000000000000000000000000002308 229.0
HKD3_k127_6663392_4 Cytochrome K12262 - - 0.00000000000000000000000000000000000000004715 158.0
HKD3_k127_6663392_5 YceI-like domain - - - 0.000000000000000000000000000000000000001327 161.0
HKD3_k127_6663392_6 YceI-like domain - - - 0.00000000000000000000000000000000000003059 153.0
HKD3_k127_680791_0 Receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 595.0
HKD3_k127_680791_1 Prolyl oligopeptidase, N-terminal beta-propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 578.0
HKD3_k127_680791_10 BAAT / Acyl-CoA thioester hydrolase C terminal K06889 - - 0.0000000000000000000000000000000000000000000000000000000007729 218.0
HKD3_k127_680791_11 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000006969 193.0
HKD3_k127_680791_12 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000000000003518 178.0
HKD3_k127_680791_13 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000004213 177.0
HKD3_k127_680791_14 Amidohydrolase family - - - 0.00000000000000000000000000000000000000001942 171.0
HKD3_k127_680791_15 Amidohydrolase family - - - 0.000000000000000000000000000000000000000305 169.0
HKD3_k127_680791_16 Thioesterase superfamily - - - 0.0000000000000000000000000001121 120.0
HKD3_k127_680791_17 PFAM regulatory protein TetR K09017 - - 0.0000000000000000000000000006986 124.0
HKD3_k127_680791_18 endoribonuclease L-PSP - - - 0.00000000000000000000000003935 117.0
HKD3_k127_680791_19 Glyoxalase-like domain - - - 0.00000000000000000000003603 112.0
HKD3_k127_680791_2 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 535.0
HKD3_k127_680791_20 RibD C-terminal domain - - - 0.00005332 45.0
HKD3_k127_680791_3 Phenylalanine-4-hydroxylase K00500 - 1.14.16.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 487.0
HKD3_k127_680791_4 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 409.0
HKD3_k127_680791_5 Zinc-binding dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 395.0
HKD3_k127_680791_6 AbgT putative transporter family K12942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 354.0
HKD3_k127_680791_7 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 321.0
HKD3_k127_680791_8 lactoylglutathione lyase activity K21252 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004736 253.0
HKD3_k127_680791_9 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002691 252.0
HKD3_k127_6951180_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 2.534e-256 808.0
HKD3_k127_6951180_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000009551 126.0
HKD3_k127_6951180_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000003115 104.0
HKD3_k127_7025038_0 heat shock protein binding - - - 0.0 1456.0
HKD3_k127_7025038_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.0 1114.0
HKD3_k127_7025038_10 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 578.0
HKD3_k127_7025038_11 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 535.0
HKD3_k127_7025038_12 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 511.0
HKD3_k127_7025038_13 heat shock protein binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 513.0
HKD3_k127_7025038_14 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 505.0
HKD3_k127_7025038_15 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 511.0
HKD3_k127_7025038_16 Outer membrane receptor proteins mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 508.0
HKD3_k127_7025038_17 TatD related DNase K07051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 482.0
HKD3_k127_7025038_18 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 477.0
HKD3_k127_7025038_19 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 437.0
HKD3_k127_7025038_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 0.0 1114.0
HKD3_k127_7025038_20 Subtilase family K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 449.0
HKD3_k127_7025038_21 Domain of unknown function (DUF3482) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 450.0
HKD3_k127_7025038_22 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 444.0
HKD3_k127_7025038_23 PFAM Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 446.0
HKD3_k127_7025038_24 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009618 414.0
HKD3_k127_7025038_25 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 370.0
HKD3_k127_7025038_26 Ferric iron ABC transporter, ATP-binding protein K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 352.0
HKD3_k127_7025038_27 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 345.0
HKD3_k127_7025038_28 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 338.0
HKD3_k127_7025038_29 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009027 327.0
HKD3_k127_7025038_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0 1033.0
HKD3_k127_7025038_30 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 295.0
HKD3_k127_7025038_31 COGs COG5616 integral membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004823 304.0
HKD3_k127_7025038_32 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007339 310.0
HKD3_k127_7025038_33 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 285.0
HKD3_k127_7025038_34 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000002482 238.0
HKD3_k127_7025038_35 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000003758 244.0
HKD3_k127_7025038_36 COG2863 Cytochrome c553 - - - 0.000000000000000000000000000000000000000000000000000000000001896 216.0
HKD3_k127_7025038_37 COG2015 Alkyl sulfatase and related hydrolases - - - 0.00000000000000000000000000000000000000000000000000000008739 201.0
HKD3_k127_7025038_38 Metallo-peptidase family M12B Reprolysin-like - - - 0.0000000000000000000000000000000000000000000000000108 202.0
HKD3_k127_7025038_39 - - - - 0.00000000000000000000000000000000000000000000000004991 190.0
HKD3_k127_7025038_4 ABC-type multidrug transport system, ATPase K06147,K18893 - - 8.468e-299 927.0
HKD3_k127_7025038_40 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000005338 190.0
HKD3_k127_7025038_41 Acid phosphatase homologues - - - 0.000000000000000000000000000000000000000000000009914 185.0
HKD3_k127_7025038_42 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000001119 160.0
HKD3_k127_7025038_43 Protein of unknown function (DUF4242) - - - 0.000000000000000000000000000004853 121.0
HKD3_k127_7025038_44 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000453 117.0
HKD3_k127_7025038_45 Ankyrin repeat K21440 GO:0006810,GO:0008150,GO:0016192,GO:0016197,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0098876,GO:1990126 - 0.000000000000000000000000009816 127.0
HKD3_k127_7025038_46 cytochrome K08738 - - 0.000000000000000000001189 104.0
HKD3_k127_7025038_47 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.000000000000000000002345 110.0
HKD3_k127_7025038_48 MarR family - - - 0.00000000000000000006564 96.0
HKD3_k127_7025038_49 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000001529 73.0
HKD3_k127_7025038_5 TonB dependent receptor - - - 7.755e-283 891.0
HKD3_k127_7025038_50 Fibronectin type III domain K03933,K12567 - 2.7.11.1 0.00000000001123 78.0
HKD3_k127_7025038_51 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000000009483 71.0
HKD3_k127_7025038_52 Tetratricopeptide repeat K02200 - - 0.000000002233 67.0
HKD3_k127_7025038_53 Sel1 domain protein repeat-containing protein K07126 - - 0.000166 55.0
HKD3_k127_7025038_6 TonB dependent receptor - - - 1.396e-234 747.0
HKD3_k127_7025038_7 COG3420 Nitrous oxidase accessory protein - - - 6.787e-226 730.0
HKD3_k127_7025038_8 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 4.498e-212 672.0
HKD3_k127_7025038_9 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.887e-208 666.0
HKD3_k127_7045624_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 461.0
HKD3_k127_7045624_1 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 444.0
HKD3_k127_7045624_2 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007154 336.0
HKD3_k127_7045624_3 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000006587 283.0
HKD3_k127_7097951_0 Acetolactate synthase K01652 - 2.2.1.6 3.628e-298 927.0
HKD3_k127_7097951_1 poly-beta-hydroxybutyrate polymerase K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 602.0
HKD3_k127_7097951_10 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 362.0
HKD3_k127_7097951_11 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 364.0
HKD3_k127_7097951_12 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 306.0
HKD3_k127_7097951_13 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005102 269.0
HKD3_k127_7097951_14 Glutathione S-transferase, C-terminal domain K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000006757 260.0
HKD3_k127_7097951_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000004069 243.0
HKD3_k127_7097951_16 Biotin-lipoyl like K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000002268 233.0
HKD3_k127_7097951_17 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000002417 231.0
HKD3_k127_7097951_18 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000000000000000007713 201.0
HKD3_k127_7097951_19 universal stress protein K14055 - - 0.0000000000000000000000000000000000000000000000000000002366 207.0
HKD3_k127_7097951_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 542.0
HKD3_k127_7097951_20 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000009851 179.0
HKD3_k127_7097951_21 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000001494 175.0
HKD3_k127_7097951_22 acetolactate synthase, small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000005815 162.0
HKD3_k127_7097951_23 Complex I intermediate-associated protein 30 (CIA30) - - - 0.000000000000000000000000000000000001439 145.0
HKD3_k127_7097951_24 Ferredoxin - - - 0.00000000000000000000000000000000007597 137.0
HKD3_k127_7097951_25 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000002132 130.0
HKD3_k127_7097951_26 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000004582 96.0
HKD3_k127_7097951_28 Glutathione peroxidase K00432 - 1.11.1.9 0.000000002441 58.0
HKD3_k127_7097951_3 alcohol dehydrogenase K00001,K00055 - 1.1.1.1,1.1.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 490.0
HKD3_k127_7097951_4 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006586 484.0
HKD3_k127_7097951_5 Reductase C-terminal K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 443.0
HKD3_k127_7097951_6 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 422.0
HKD3_k127_7097951_7 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005665 411.0
HKD3_k127_7097951_8 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 421.0
HKD3_k127_7097951_9 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 372.0
HKD3_k127_7178171_0 CHASE2 domain protein - - - 9.334e-230 733.0
HKD3_k127_7178171_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008331 608.0
HKD3_k127_7178171_10 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000002407 207.0
HKD3_k127_7178171_12 YCII-related domain - - - 0.00000000000000000000000000000000000000002005 159.0
HKD3_k127_7178171_13 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000008296 146.0
HKD3_k127_7178171_14 FOG TPR repeat SEL1 subfamily K07126 - - 0.000000000000000000006554 102.0
HKD3_k127_7178171_15 Associated with various cellular activities K03924 - - 0.00000000000000000004927 93.0
HKD3_k127_7178171_16 Protein of unknown function (DUF3303) - - - 0.000000000000256 77.0
HKD3_k127_7178171_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 406.0
HKD3_k127_7178171_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 379.0
HKD3_k127_7178171_4 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 338.0
HKD3_k127_7178171_5 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 324.0
HKD3_k127_7178171_6 Alpha/beta hydrolase family K01259,K18457 - 3.4.11.5,3.5.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000003702 264.0
HKD3_k127_7178171_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000004361 222.0
HKD3_k127_7178171_8 carboxylic ester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000001452 214.0
HKD3_k127_7178171_9 Trypsin-like serine protease - - - 0.00000000000000000000000000000000000000000000000000000002137 216.0
HKD3_k127_7253243_0 FAD linked oxidase domain protein - - - 0.0 1948.0
HKD3_k127_7253243_1 Peptidase family M49 - - - 8.356e-216 683.0
HKD3_k127_7253243_10 Domain of unknown function (DUF1330) - - - 0.0000000000000000000001053 105.0
HKD3_k127_7253243_11 - - - - 0.0000000000000000000005784 103.0
HKD3_k127_7253243_12 - - - - 0.000000000000000001041 96.0
HKD3_k127_7253243_13 OsmC-like protein - - - 0.0000000000002044 79.0
HKD3_k127_7253243_14 Protein of unknown function (DUF2934) - - - 0.0000000003712 69.0
HKD3_k127_7253243_2 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 417.0
HKD3_k127_7253243_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 401.0
HKD3_k127_7253243_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000003708 252.0
HKD3_k127_7253243_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000008381 216.0
HKD3_k127_7253243_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000001612 176.0
HKD3_k127_7253243_8 Prokaryotic dksA/traR C4-type zinc finger - - - 0.000000000000000000000000004002 115.0
HKD3_k127_7253243_9 Outer membrane protein beta-barrel domain - - - 0.00000000000000000000001212 112.0
HKD3_k127_7266757_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.812e-251 785.0
HKD3_k127_7266757_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 347.0
HKD3_k127_7266757_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 293.0
HKD3_k127_7266757_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001086 241.0
HKD3_k127_7266757_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001545 243.0
HKD3_k127_7266757_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000004314 167.0
HKD3_k127_7266757_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000000000000000000002073 116.0
HKD3_k127_7286543_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.562e-312 975.0
HKD3_k127_7286543_1 - - - - 9.776e-210 674.0
HKD3_k127_7286543_10 Ribonuclease - - - 0.00000000000000000000000000000000000000003873 156.0
HKD3_k127_7286543_11 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000006157 138.0
HKD3_k127_7286543_12 Barstar (barnase inhibitor) - - - 0.000000000000000000000446 113.0
HKD3_k127_7286543_13 - - - - 0.00000000000000000001342 93.0
HKD3_k127_7286543_14 PFAM TPR repeat-containing protein - - - 0.000007169 55.0
HKD3_k127_7286543_2 Mechanosensitive ion channel K05802 - - 6.69e-208 676.0
HKD3_k127_7286543_3 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 GO:0000272,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005976,GO:0005977,GO:0005980,GO:0006073,GO:0006091,GO:0006112,GO:0008144,GO:0008150,GO:0008152,GO:0008184,GO:0009056,GO:0009057,GO:0009251,GO:0009987,GO:0015980,GO:0016052,GO:0016740,GO:0016757,GO:0016758,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901575 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 459.0
HKD3_k127_7286543_4 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 434.0
HKD3_k127_7286543_5 efflux protein, MATE family K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 434.0
HKD3_k127_7286543_6 PFAM Pyrrolo-quinoline quinone - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 414.0
HKD3_k127_7286543_7 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000008253 197.0
HKD3_k127_7286543_8 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000007058 192.0
HKD3_k127_7286543_9 Cobalt uptake substrate-specific transmembrane region - - - 0.00000000000000000000000000000000000000000003066 169.0
HKD3_k127_7288830_0 Type II secretory pathway, component HofQ K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 381.0
HKD3_k127_7288830_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000000001147 196.0
HKD3_k127_7295990_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 6.107e-271 846.0
HKD3_k127_7295990_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 493.0
HKD3_k127_7295990_2 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002948 264.0
HKD3_k127_7295990_3 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000001525 165.0
HKD3_k127_7295990_4 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000008357 158.0
HKD3_k127_7295990_5 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000003069 55.0
HKD3_k127_7310696_0 ABC-type multidrug transport system ATPase and permease K06147 - - 1.437e-277 865.0
HKD3_k127_7310696_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.067e-232 740.0
HKD3_k127_7310696_10 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000001457 193.0
HKD3_k127_7310696_11 COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog K03088 - - 0.000000000000000000000000000000000000000000000007011 179.0
HKD3_k127_7310696_12 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000002201 174.0
HKD3_k127_7310696_13 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000004285 101.0
HKD3_k127_7310696_14 Sporulation related domain - - - 0.0000000000000001212 89.0
HKD3_k127_7310696_15 self proteolysis - - - 0.000000007056 72.0
HKD3_k127_7310696_16 Protein of unknown function (DUF3106) - - - 0.000003571 58.0
HKD3_k127_7310696_17 - - - - 0.0006609 49.0
HKD3_k127_7310696_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 7.583e-230 732.0
HKD3_k127_7310696_3 Insecticidal toxin complex protein TcaC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 669.0
HKD3_k127_7310696_4 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 561.0
HKD3_k127_7310696_5 NADH:flavin oxidoreductase / NADH oxidase family K00317,K21833 - 1.5.8.1,1.5.8.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 514.0
HKD3_k127_7310696_6 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 496.0
HKD3_k127_7310696_7 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008252 473.0
HKD3_k127_7310696_8 transcriptional regulator K13634 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 391.0
HKD3_k127_7310696_9 PFAM Phosphate-selective porin O K07221 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 362.0
HKD3_k127_7347441_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 3.829e-256 796.0
HKD3_k127_7347441_1 COG4772 Outer membrane receptor for Fe3 -dicitrate K16091 - - 5.57e-205 661.0
HKD3_k127_7347441_2 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 490.0
HKD3_k127_7347441_3 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 411.0
HKD3_k127_7347441_4 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000002221 247.0
HKD3_k127_7347441_5 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001231 242.0
HKD3_k127_7347441_6 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000009973 211.0
HKD3_k127_7347441_7 maturation - - - 0.00000000000000000000000000000000000000002204 164.0
HKD3_k127_7347441_8 NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000018 111.0
HKD3_k127_7347441_9 Domain of unknown function (DUF5122) beta-propeller - - - 0.00000000000000000000006229 115.0
HKD3_k127_7360741_0 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 6.64e-228 724.0
HKD3_k127_7360741_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 479.0
HKD3_k127_7360741_10 Zn-dependent dipeptidase, microsomal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000001062 173.0
HKD3_k127_7360741_11 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000002267 152.0
HKD3_k127_7360741_12 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000417 135.0
HKD3_k127_7360741_13 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000003434 118.0
HKD3_k127_7360741_14 - - - - 0.00000000000000002017 96.0
HKD3_k127_7360741_15 - - - - 0.00000000000951 76.0
HKD3_k127_7360741_16 EF-hand domain pair - - - 0.0000000001875 64.0
HKD3_k127_7360741_17 electron transfer activity K03737,K05337 - 1.2.7.1 0.0005577 53.0
HKD3_k127_7360741_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 377.0
HKD3_k127_7360741_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 356.0
HKD3_k127_7360741_4 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 357.0
HKD3_k127_7360741_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004201 348.0
HKD3_k127_7360741_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 328.0
HKD3_k127_7360741_7 Conserved TM helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 296.0
HKD3_k127_7360741_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000001101 206.0
HKD3_k127_7366180_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1018.0
HKD3_k127_7366180_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.249e-311 964.0
HKD3_k127_7366180_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000802 269.0
HKD3_k127_7366180_11 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000005561 252.0
HKD3_k127_7366180_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000971 257.0
HKD3_k127_7366180_13 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000008773 239.0
HKD3_k127_7366180_14 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000003604 220.0
HKD3_k127_7366180_15 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000001925 211.0
HKD3_k127_7366180_16 RNA-binding protein K07574 - - 0.00000000000000000000000009426 112.0
HKD3_k127_7366180_17 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000000001155 108.0
HKD3_k127_7366180_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 7.037e-248 767.0
HKD3_k127_7366180_3 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 5.518e-244 801.0
HKD3_k127_7366180_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.212e-215 675.0
HKD3_k127_7366180_5 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 508.0
HKD3_k127_7366180_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 474.0
HKD3_k127_7366180_7 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 320.0
HKD3_k127_7366180_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 313.0
HKD3_k127_7366180_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 303.0
HKD3_k127_7417933_0 Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second K01958 - 6.4.1.1 0.0 1585.0
HKD3_k127_7417933_1 Peptidase family M3 K01392 - 3.4.24.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005476 623.0
HKD3_k127_7417933_10 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001768 301.0
HKD3_k127_7417933_11 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001092 273.0
HKD3_k127_7417933_12 Highly conserved protein containing a thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000326 254.0
HKD3_k127_7417933_13 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000476 239.0
HKD3_k127_7417933_14 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000002274 200.0
HKD3_k127_7417933_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000002958 131.0
HKD3_k127_7417933_16 PEP-CTERM motif - - - 0.000000000000000000000000000001216 131.0
HKD3_k127_7417933_17 Two component transcriptional regulator, LuxR family K14987 - - 0.000000000000000000000002396 109.0
HKD3_k127_7417933_18 Protein of unknown function (DUF2845) - - - 0.00000000000006562 78.0
HKD3_k127_7417933_19 endopeptidase activity - - - 0.0000001949 65.0
HKD3_k127_7417933_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 603.0
HKD3_k127_7417933_20 cellulose binding K01179 - 3.2.1.4 0.00002312 58.0
HKD3_k127_7417933_3 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 625.0
HKD3_k127_7417933_4 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 572.0
HKD3_k127_7417933_5 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 553.0
HKD3_k127_7417933_6 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 398.0
HKD3_k127_7417933_7 DnaJ-class molecular chaperone K05516 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007745 381.0
HKD3_k127_7417933_8 Metallo-peptidase family M12B Reprolysin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 353.0
HKD3_k127_7417933_9 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 332.0
HKD3_k127_7423918_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 6.279e-288 907.0
HKD3_k127_7423918_1 Participates in both transcription termination and antitermination K02600 - - 2.692e-224 707.0
HKD3_k127_7423918_10 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000009981 151.0
HKD3_k127_7423918_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000005438 59.0
HKD3_k127_7423918_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 610.0
HKD3_k127_7423918_3 homogentisate 1,2-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 604.0
HKD3_k127_7423918_4 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 530.0
HKD3_k127_7423918_5 GMP synthase (glutamine-hydrolyzing) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 487.0
HKD3_k127_7423918_6 Fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 453.0
HKD3_k127_7423918_7 COG1448 Aspartate tyrosine aromatic aminotransferase K00813,K00832 - 2.6.1.1,2.6.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 392.0
HKD3_k127_7423918_8 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 374.0
HKD3_k127_7436559_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1176.0
HKD3_k127_7436559_1 phenazine biosynthesis protein PhzF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 398.0
HKD3_k127_7436559_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002919 288.0
HKD3_k127_7436559_3 Heavy metal translocating P-type atpase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000006574 171.0
HKD3_k127_7436559_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000001774 126.0
HKD3_k127_7436559_5 heavy metal transport detoxification protein K07213 - - 0.000000000001138 70.0
HKD3_k127_7436559_6 Glycosyl transferase, family 2 - - - 0.0000000002142 63.0
HKD3_k127_7438467_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008986,GO:0009058,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016781,GO:0019318,GO:0019319,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0071704,GO:1901576 2.7.9.2 0.0 1158.0
HKD3_k127_7438467_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1115.0
HKD3_k127_7438467_10 Thi4 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 596.0
HKD3_k127_7438467_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007814 584.0
HKD3_k127_7438467_12 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009869 580.0
HKD3_k127_7438467_13 Peptidase family S58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 561.0
HKD3_k127_7438467_14 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 495.0
HKD3_k127_7438467_15 Amino acid permease K03294,K03759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 479.0
HKD3_k127_7438467_16 Glycine cleavage T-protein C-terminal barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 459.0
HKD3_k127_7438467_17 FAD binding domain K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 423.0
HKD3_k127_7438467_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 407.0
HKD3_k127_7438467_19 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 403.0
HKD3_k127_7438467_2 Oxidoreductase - - - 3.389e-303 947.0
HKD3_k127_7438467_20 Dehydrogenase K15054 - 1.1.99.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 392.0
HKD3_k127_7438467_21 PFAM oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 366.0
HKD3_k127_7438467_22 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0030234,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0065007,GO:0065009,GO:0098772 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
HKD3_k127_7438467_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001399 276.0
HKD3_k127_7438467_24 Protein of unknown function (DUF1249) K09920 - - 0.00000000000000000000000001488 115.0
HKD3_k127_7438467_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 1.207e-265 838.0
HKD3_k127_7438467_4 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 3.351e-260 815.0
HKD3_k127_7438467_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.739e-252 812.0
HKD3_k127_7438467_6 Aldehyde dehydrogenase family K00294 - 1.2.1.88 8.997e-250 801.0
HKD3_k127_7438467_7 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 7.808e-235 747.0
HKD3_k127_7438467_8 Glycolate oxidase subunit GlcD K00104 - 1.1.3.15 1.193e-214 676.0
HKD3_k127_7438467_9 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 7.532e-206 649.0
HKD3_k127_7535811_0 TIGRFAM penicillin-binding protein, 1A K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 415.0
HKD3_k127_7535811_1 Pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 366.0
HKD3_k127_7535811_2 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000001321 221.0
HKD3_k127_7535811_3 PFAM Fimbrial assembly K02663 - - 0.00000000000000000000000000000000000000000000008766 175.0
HKD3_k127_7535811_4 pilus assembly protein pilp K02665 - - 0.000000000000000000000000000000000000000001191 164.0
HKD3_k127_7535811_5 Type IV pilus biogenesis protein PilQ K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.000000000000000000002903 105.0
HKD3_k127_7594726_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 1.99e-231 736.0
HKD3_k127_7594726_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 4.496e-208 655.0
HKD3_k127_7594726_10 Ferredoxin - - - 0.0000000000000004994 79.0
HKD3_k127_7594726_11 - - - - 0.000000000001686 80.0
HKD3_k127_7594726_12 - - - - 0.00000000001025 65.0
HKD3_k127_7594726_2 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 618.0
HKD3_k127_7594726_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 573.0
HKD3_k127_7594726_4 Radical SAM superfamily K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 544.0
HKD3_k127_7594726_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 485.0
HKD3_k127_7594726_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042802,GO:0043021,GO:0043022,GO:0043170,GO:0043335,GO:0043412,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0050896,GO:0051083,GO:0061077,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 398.0
HKD3_k127_7594726_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 346.0
HKD3_k127_7594726_8 YMGG-like Gly-zipper - - - 0.00000000000000000000000006839 115.0
HKD3_k127_7594726_9 Protein of unknown function (DUF2490) - - - 0.0000000000000000000000113 109.0
HKD3_k127_7662026_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 477.0
HKD3_k127_7688341_0 AMP-binding enzyme K01897 - 6.2.1.3 5.613e-242 759.0
HKD3_k127_7688341_1 AMP-binding enzyme - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 2.212e-207 659.0
HKD3_k127_7688341_10 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 451.0
HKD3_k127_7688341_11 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 450.0
HKD3_k127_7688341_12 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 437.0
HKD3_k127_7688341_13 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 419.0
HKD3_k127_7688341_14 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 410.0
HKD3_k127_7688341_15 PFAM Dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 415.0
HKD3_k127_7688341_16 abc transporter atp-binding protein K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 394.0
HKD3_k127_7688341_17 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008112 389.0
HKD3_k127_7688341_18 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 366.0
HKD3_k127_7688341_19 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009138 374.0
HKD3_k127_7688341_2 Penicillin amidase K01434 - 3.5.1.11 2.681e-197 640.0
HKD3_k127_7688341_20 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 346.0
HKD3_k127_7688341_21 Sodium ABC transporter permease K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 347.0
HKD3_k127_7688341_22 TonB-dependent receptor plug K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 358.0
HKD3_k127_7688341_23 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 338.0
HKD3_k127_7688341_24 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008995 330.0
HKD3_k127_7688341_25 2-hydroxychromene-2-carboxylate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000543 326.0
HKD3_k127_7688341_26 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 329.0
HKD3_k127_7688341_27 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 324.0
HKD3_k127_7688341_28 COG0564 Pseudouridylate synthases, 23S RNA-specific K06175 - 5.4.99.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 289.0
HKD3_k127_7688341_29 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007283 285.0
HKD3_k127_7688341_3 COG0076 Glutamate decarboxylase and related PLP-dependent proteins K01634 - 4.1.2.27 5.652e-195 618.0
HKD3_k127_7688341_30 Alanine racemase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001675 285.0
HKD3_k127_7688341_31 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009023 267.0
HKD3_k127_7688341_32 Fungal family of unknown function (DUF1776) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001283 261.0
HKD3_k127_7688341_33 Belongs to the UPF0502 family K09915 - - 0.000000000000000000000000000000000000000000000000000000000000000000001524 255.0
HKD3_k127_7688341_34 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - 0.0000000000000000000000000000000000000000000000000000000000000000006404 253.0
HKD3_k127_7688341_35 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000009096 231.0
HKD3_k127_7688341_36 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00245 - 1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000008257 214.0
HKD3_k127_7688341_37 membrane - - - 0.00000000000000000000000000000000000000000000000000000003854 204.0
HKD3_k127_7688341_38 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000000003237 194.0
HKD3_k127_7688341_39 Cytochrome c mono- and diheme variants - - - 0.00000000000000000000000000000000000000000002138 168.0
HKD3_k127_7688341_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 535.0
HKD3_k127_7688341_40 proteolysis - - - 0.0000000000000000000000000000000000000000002653 179.0
HKD3_k127_7688341_41 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000006493 151.0
HKD3_k127_7688341_42 Acyl-ACP thioesterase K07107 - - 0.00000000000000000000000000000000000003352 163.0
HKD3_k127_7688341_43 Thermostable hemolysin - - - 0.000000000000000000000000000000000007071 146.0
HKD3_k127_7688341_44 DNA-templated transcription, initiation K03088,K03091 - - 0.00000000000000000000000000000001094 135.0
HKD3_k127_7688341_45 TetR family transcriptional regulator - - - 0.00000000000000000000000000000003803 141.0
HKD3_k127_7688341_46 - - - - 0.00000000000000000000000000003572 123.0
HKD3_k127_7688341_47 Transcription factor zinc-finger K09981 - - 0.00000000000000000000004563 102.0
HKD3_k127_7688341_48 Fe2 -dicitrate sensor, membrane component K07165 - - 0.0000005858 62.0
HKD3_k127_7688341_5 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 526.0
HKD3_k127_7688341_6 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 487.0
HKD3_k127_7688341_7 PFAM Ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 474.0
HKD3_k127_7688341_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 469.0
HKD3_k127_7688341_9 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 467.0
HKD3_k127_7740114_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 434.0
HKD3_k127_7740114_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 322.0
HKD3_k127_7740114_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 331.0
HKD3_k127_7740114_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000001253 170.0
HKD3_k127_7740114_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000001129 148.0
HKD3_k127_7740114_5 TonB C terminal K03646 - - 0.0000000000000007687 87.0
HKD3_k127_774287_0 Exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000001753 209.0
HKD3_k127_774287_1 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000000000000000000000000000000002201 130.0
HKD3_k127_774287_2 Protein conserved in bacteria - - - 0.00000000000000000000000009614 109.0
HKD3_k127_774287_3 Protein of unknown function (DUF2845) - - - 0.00000002866 59.0
HKD3_k127_7774986_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1313.0
HKD3_k127_7774986_1 N-acyl-D-aspartate D-glutamate deacylase - - - 8.193e-207 659.0
HKD3_k127_7774986_10 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000004637 227.0
HKD3_k127_7774986_11 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000008684 205.0
HKD3_k127_7774986_12 Indole-3-glycerol phosphate synthase K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.000000000000000000000000000000000000000001116 171.0
HKD3_k127_7774986_13 Rhodanese Homology Domain - - - 0.000000000000000000000000000001884 123.0
HKD3_k127_7774986_14 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000003267 126.0
HKD3_k127_7774986_15 sulfurtransferase - - - 0.00000000000000000001366 98.0
HKD3_k127_7774986_16 Member of a two-component regulatory system K07644 - 2.7.13.3 0.0000000001291 68.0
HKD3_k127_7774986_2 Pyridine nucleotide-disulphide oxidoreductase - - - 1.068e-197 623.0
HKD3_k127_7774986_3 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 531.0
HKD3_k127_7774986_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 488.0
HKD3_k127_7774986_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 409.0
HKD3_k127_7774986_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 301.0
HKD3_k127_7774986_7 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001188 295.0
HKD3_k127_7774986_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000004848 275.0
HKD3_k127_7774986_9 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 258.0
HKD3_k127_7814848_0 helix_turn_helix, Lux Regulon K03556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 468.0
HKD3_k127_7814848_1 Kelch - - - 0.000000000000000000000000000000000000000000000008006 190.0
HKD3_k127_7814848_2 nucleoside-diphosphate sugar epimerase K07071 - - 0.000000000000000000000000000000004145 130.0
HKD3_k127_7902585_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 439.0
HKD3_k127_7902585_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003924 280.0
HKD3_k127_7902585_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000001875 154.0
HKD3_k127_7913264_0 Belongs to the glycosyl hydrolase 13 family K01200 - 3.2.1.41 2.031e-240 785.0
HKD3_k127_7913264_1 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 386.0
HKD3_k127_7913264_2 EcsC protein family - - - 0.000000000000000000000000000000000000000000000003635 184.0
HKD3_k127_7913264_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01895 - 6.2.1.1 0.0000003456 61.0
HKD3_k127_7972502_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1172.0
HKD3_k127_7972502_1 Sulfate transporter K03321 - - 1.022e-237 746.0
HKD3_k127_7972502_10 Protein of unknown function - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 384.0
HKD3_k127_7972502_11 ribonuclease BN K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 328.0
HKD3_k127_7972502_12 Type II secretory pathway component ExeA K02450,K12283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 323.0
HKD3_k127_7972502_13 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 313.0
HKD3_k127_7972502_14 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006166 281.0
HKD3_k127_7972502_15 DNA polymerase III, delta subunit K02340 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0032991,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000005543 264.0
HKD3_k127_7972502_16 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000009283 234.0
HKD3_k127_7972502_17 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000006059 232.0
HKD3_k127_7972502_18 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000001987 212.0
HKD3_k127_7972502_19 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0042803,GO:0043021,GO:0043022,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046983,GO:0070037,GO:0070038,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.177 0.000000000000000000000000000000000000000000000002629 177.0
HKD3_k127_7972502_2 modulator of DNA gyrase K03568 - - 8.84e-216 679.0
HKD3_k127_7972502_20 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000005537 171.0
HKD3_k127_7972502_21 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000006562 175.0
HKD3_k127_7972502_22 protein conserved in bacteria K09950 - - 0.000000000000000000000000000000000000001094 154.0
HKD3_k127_7972502_23 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000009297 146.0
HKD3_k127_7972502_24 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000111 118.0
HKD3_k127_7972502_25 Lipopolysaccharide-assembly - - - 0.00000000000001973 82.0
HKD3_k127_7972502_3 TIGRFAM ribonuclease, Rne Rng family K08301 - - 2.393e-197 630.0
HKD3_k127_7972502_4 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 540.0
HKD3_k127_7972502_5 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 490.0
HKD3_k127_7972502_6 ABC transporter permease K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 431.0
HKD3_k127_7972502_7 5-(carboxyamino)imidazole ribonucleotide synthase activity K01589 GO:0000166,GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016829,GO:0016830,GO:0016831,GO:0016874,GO:0016879,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034028,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 407.0
HKD3_k127_7972502_8 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 395.0
HKD3_k127_7972502_9 ABC transporter substrate-binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 391.0
HKD3_k127_7980359_0 peptidase K01278 - 3.4.14.5 5.433e-244 776.0
HKD3_k127_7980359_1 COG1505 Serine proteases of the peptidase family S9A K01322 - 3.4.21.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 399.0
HKD3_k127_8311152_0 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 472.0
HKD3_k127_8311152_1 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 439.0
HKD3_k127_8311152_2 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 373.0
HKD3_k127_8470306_0 Belongs to the GSP D family K02666 - - 0.00000000000000000000000000000000000000000000001876 185.0
HKD3_k127_8470306_1 PFAM Peptidoglycan-binding domain 1 protein K02450 - - 0.0000000000000000000000000000000000000000007473 162.0
HKD3_k127_8484190_0 ABC transporter - - - 2.48e-253 787.0
HKD3_k127_8484190_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 5.297e-217 687.0
HKD3_k127_8484190_10 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000002004 206.0
HKD3_k127_8484190_11 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000004054 175.0
HKD3_k127_8484190_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000001742 139.0
HKD3_k127_8484190_13 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000001602 95.0
HKD3_k127_8484190_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 479.0
HKD3_k127_8484190_3 PFAM histone deacetylase superfamily K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 400.0
HKD3_k127_8484190_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 398.0
HKD3_k127_8484190_5 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009081 342.0
HKD3_k127_8484190_6 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 341.0
HKD3_k127_8484190_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 299.0
HKD3_k127_8484190_8 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000006979 256.0
HKD3_k127_8484190_9 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000004107 232.0
HKD3_k127_8496192_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1262.0
HKD3_k127_8496192_1 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0 1202.0
HKD3_k127_8496192_10 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 531.0
HKD3_k127_8496192_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 502.0
HKD3_k127_8496192_12 NAD dependent epimerase/dehydratase family K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002752 400.0
HKD3_k127_8496192_13 FeS assembly ATPase SufC K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 402.0
HKD3_k127_8496192_14 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 381.0
HKD3_k127_8496192_15 PFAM ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 343.0
HKD3_k127_8496192_16 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 335.0
HKD3_k127_8496192_17 ErfK YbiS YcfS YnhG K16291 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 327.0
HKD3_k127_8496192_18 Responsible for synthesis of pseudouridine from uracil K06179 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 317.0
HKD3_k127_8496192_19 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 316.0
HKD3_k127_8496192_2 Dehydrogenase E1 component K00164 GO:0003674,GO:0003824,GO:0004591,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016624,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0055114,GO:0071704,GO:0072350,GO:1902494,GO:1990204,GO:1990234 1.2.4.2 0.0 1132.0
HKD3_k127_8496192_20 Nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 316.0
HKD3_k127_8496192_21 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 314.0
HKD3_k127_8496192_22 FeS assembly protein SufD K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002819 296.0
HKD3_k127_8496192_23 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000008859 262.0
HKD3_k127_8496192_24 TIGRFAM FeS assembly SUF system protein SufT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002745 259.0
HKD3_k127_8496192_25 Secondary metabolites biosynthesis, transport, and catabolism K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006759 262.0
HKD3_k127_8496192_26 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002471 255.0
HKD3_k127_8496192_27 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001136 270.0
HKD3_k127_8496192_28 Thioredoxin domain-containing protein K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000001374 234.0
HKD3_k127_8496192_29 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000004331 243.0
HKD3_k127_8496192_3 TIGRFAM FeS assembly protein SufB K09014 - - 2.326e-270 837.0
HKD3_k127_8496192_30 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000465 228.0
HKD3_k127_8496192_31 (Lipo)protein K04754 - - 0.000000000000000000000000000000000000000000000000000000000006558 217.0
HKD3_k127_8496192_32 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000002823 213.0
HKD3_k127_8496192_33 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000974 207.0
HKD3_k127_8496192_34 PFAM Amino acid-binding ACT K03567 - - 0.0000000000000000000000000000000000000000000000000000009372 198.0
HKD3_k127_8496192_35 Maf-like protein - - - 0.000000000000000000000000000000000000000000000000000001638 201.0
HKD3_k127_8496192_36 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.000000000000000000000000000000000000000000000000000004404 198.0
HKD3_k127_8496192_37 low molecular weight K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000000005715 191.0
HKD3_k127_8496192_38 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000001813 184.0
HKD3_k127_8496192_39 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000005431 182.0
HKD3_k127_8496192_4 SMART Nucleotide binding protein, PINc K07175 - - 1.495e-217 684.0
HKD3_k127_8496192_40 ABC-type transport system involved in resistance to organic solvents auxiliary component K07323 - - 0.0000000000000000000000000000000000000000009045 164.0
HKD3_k127_8496192_41 salt-induced outer membrane protein K07283 - - 0.000000000000000000000000000000000000000004594 175.0
HKD3_k127_8496192_42 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000000000000000000000000000001259 153.0
HKD3_k127_8496192_43 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000001724 153.0
HKD3_k127_8496192_44 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.00000000000000000000000000000000000005979 147.0
HKD3_k127_8496192_45 MlaD protein K02067 - - 0.000000000000000000000000000000000002289 155.0
HKD3_k127_8496192_46 transcriptional regulator - - - 0.000000000000000000000000000000000003613 142.0
HKD3_k127_8496192_47 Small Multidrug Resistance protein K03297 - - 0.00000000000000000000000000000000001197 143.0
HKD3_k127_8496192_48 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.0000000000000000000000000000000001175 137.0
HKD3_k127_8496192_49 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000005251 133.0
HKD3_k127_8496192_5 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.308e-213 691.0
HKD3_k127_8496192_50 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000001024 93.0
HKD3_k127_8496192_51 - - - - 0.000000000000000006819 90.0
HKD3_k127_8496192_52 metal-binding, possibly nucleic acid-binding protein K07040 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000007034 84.0
HKD3_k127_8496192_54 Phosphoglycerate mutase family - - - 0.0000000000007335 76.0
HKD3_k127_8496192_55 nuclear chromosome segregation - - - 0.0000001118 63.0
HKD3_k127_8496192_56 STAS domain K07122 - - 0.0000008074 57.0
HKD3_k127_8496192_57 Phage integrase family - - - 0.0001857 44.0
HKD3_k127_8496192_58 Recombinase zinc beta ribbon domain - - - 0.0004008 52.0
HKD3_k127_8496192_6 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 6.098e-199 644.0
HKD3_k127_8496192_7 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 566.0
HKD3_k127_8496192_8 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 574.0
HKD3_k127_8496192_9 Serine dehydratase beta chain K01752 GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005801 550.0
HKD3_k127_8501543_0 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 339.0
HKD3_k127_8501543_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000008497 247.0
HKD3_k127_8501543_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008097 244.0
HKD3_k127_8501543_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000275 141.0
HKD3_k127_8542487_0 Mechanosensitive ion channel K05802 - - 5.477e-208 668.0
HKD3_k127_8585007_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1154.0
HKD3_k127_8585007_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.28e-207 653.0
HKD3_k127_8585007_10 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 331.0
HKD3_k127_8585007_11 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006853 317.0
HKD3_k127_8585007_12 ATPases associated with a variety of cellular activities K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 301.0
HKD3_k127_8585007_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004436 274.0
HKD3_k127_8585007_14 PFAM glutathione-dependent formaldehyde-activating GFA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000943 267.0
HKD3_k127_8585007_15 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000756 276.0
HKD3_k127_8585007_16 NAD dependent epimerase/dehydratase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 266.0
HKD3_k127_8585007_17 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 260.0
HKD3_k127_8585007_18 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000591 283.0
HKD3_k127_8585007_19 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003161 261.0
HKD3_k127_8585007_2 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.15e-200 638.0
HKD3_k127_8585007_20 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003954 245.0
HKD3_k127_8585007_21 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000002236 213.0
HKD3_k127_8585007_22 Thioesterase - - - 0.0000000000000000000000000000000000000000000000000000000006013 225.0
HKD3_k127_8585007_23 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000001741 194.0
HKD3_k127_8585007_24 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000001762 189.0
HKD3_k127_8585007_25 WHG domain - - - 0.00000000000000000000000000000000000000000000000004052 187.0
HKD3_k127_8585007_26 negative regulation of transcription, DNA-templated K10947 - - 0.00000000000000000000000000000000000001574 147.0
HKD3_k127_8585007_27 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000001027 163.0
HKD3_k127_8585007_28 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067,K06192 - - 0.0000000000000000000000000000000002519 144.0
HKD3_k127_8585007_29 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000002897 142.0
HKD3_k127_8585007_3 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 589.0
HKD3_k127_8585007_30 enzyme of heme biosynthesis K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000575 140.0
HKD3_k127_8585007_31 protein conserved in bacteria K09921 - - 0.00000000000000000000000000002088 135.0
HKD3_k127_8585007_32 Putative prokaryotic signal transducing protein - - - 0.000000000000000000000001268 106.0
HKD3_k127_8585007_33 Sterol-binding domain protein K03690 - - 0.000000000000000000000001935 111.0
HKD3_k127_8585007_34 Uroporphyrin-III C-methyltransferase K02496 - 2.1.1.107 0.00000000000000000005544 102.0
HKD3_k127_8585007_35 transport system auxiliary component K18480 - - 0.000000000000000002467 97.0
HKD3_k127_8585007_36 AI-2E family transporter - - - 0.0000000000000005129 81.0
HKD3_k127_8585007_37 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000003203 65.0
HKD3_k127_8585007_4 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 537.0
HKD3_k127_8585007_5 sensor diguanylate cyclase phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 424.0
HKD3_k127_8585007_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008425,GO:0008757,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016740,GO:0016741,GO:0030580,GO:0032259,GO:0042180,GO:0042181,GO:0043333,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 354.0
HKD3_k127_8585007_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 346.0
HKD3_k127_8585007_8 Belongs to the 'phage' integrase family. XerC subfamily K03733 GO:0000150,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008907,GO:0009009,GO:0009037,GO:0009987,GO:0015074,GO:0032991,GO:0034641,GO:0042150,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 342.0
HKD3_k127_8585007_9 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 331.0
HKD3_k127_8598696_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 3.383e-290 899.0
HKD3_k127_8598696_1 GTP-binding protein TypA K06207 - - 4.962e-283 881.0
HKD3_k127_8598696_10 guanyl-nucleotide exchange factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 337.0
HKD3_k127_8598696_11 N-formylglutamate amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 261.0
HKD3_k127_8598696_12 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002173 249.0
HKD3_k127_8598696_13 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000028 215.0
HKD3_k127_8598696_14 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000005123 180.0
HKD3_k127_8598696_15 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000000000003583 145.0
HKD3_k127_8598696_16 Virulence associated protein B K18829 - - 0.0000000000000000000001406 103.0
HKD3_k127_8598696_17 - - - - 0.0000000000002637 81.0
HKD3_k127_8598696_18 TIGRFAM conserved repeat domain - - - 0.00003299 53.0
HKD3_k127_8598696_2 Helicase K03722 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 629.0
HKD3_k127_8598696_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 599.0
HKD3_k127_8598696_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009052 474.0
HKD3_k127_8598696_5 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 449.0
HKD3_k127_8598696_6 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 416.0
HKD3_k127_8598696_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 374.0
HKD3_k127_8598696_8 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 350.0
HKD3_k127_8598696_9 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 338.0
HKD3_k127_8662294_0 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 477.0
HKD3_k127_8662294_1 RNA polymerase sigma factor RpoH K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 362.0
HKD3_k127_8662294_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 352.0
HKD3_k127_8662294_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000101 268.0
HKD3_k127_8662294_4 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002288 272.0
HKD3_k127_8662294_5 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000000000269 225.0
HKD3_k127_8662294_6 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000005858 151.0
HKD3_k127_8735689_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 3.28e-270 867.0
HKD3_k127_8735689_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008017 281.0
HKD3_k127_8794511_0 Nickel-dependent hydrogenase K06281 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 4.284e-309 954.0
HKD3_k127_8794511_1 ABC transporter transmembrane region K06147,K11085 - - 3.922e-217 694.0
HKD3_k127_8794511_10 Catalyzes the hydrolysis of a monocarboxylic acid amid to form a monocarboxylate and ammonia K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000001127 226.0
HKD3_k127_8794511_11 hydrogenase expression formation protein K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000008064 214.0
HKD3_k127_8794511_12 HupH hydrogenase expression protein, C-terminal conserved region K03618 - - 0.00000000000000000000000000000000000000000000004627 186.0
HKD3_k127_8794511_13 Pfam:DUF3457 - - - 0.000000000000000000000000000000000000001107 166.0
HKD3_k127_8794511_14 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000005433 104.0
HKD3_k127_8794511_15 Hydrogenase-1 expression protein HyaE K03619 - - 0.0000000000004954 80.0
HKD3_k127_8794511_2 Aldehyde dehydrogenase family - - - 1.346e-207 655.0
HKD3_k127_8794511_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 587.0
HKD3_k127_8794511_4 alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 521.0
HKD3_k127_8794511_5 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 509.0
HKD3_k127_8794511_6 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 442.0
HKD3_k127_8794511_7 Prokaryotic cytochrome b561 K03620 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001829 278.0
HKD3_k127_8794511_8 DinB superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006275 244.0
HKD3_k127_8794511_9 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000001193 223.0
HKD3_k127_8824150_0 AcrB/AcrD/AcrF family - - - 0.0 1223.0
HKD3_k127_8824150_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1162.0
HKD3_k127_8824150_10 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 296.0
HKD3_k127_8824150_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 295.0
HKD3_k127_8824150_12 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 288.0
HKD3_k127_8824150_13 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000543 293.0
HKD3_k127_8824150_14 Maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002346 274.0
HKD3_k127_8824150_15 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000008152 264.0
HKD3_k127_8824150_16 Belongs to the ATCase OTCase family K09065,K13043 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.11,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000003564 246.0
HKD3_k127_8824150_17 PFAM cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000001411 233.0
HKD3_k127_8824150_18 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000001448 206.0
HKD3_k127_8824150_19 Thioesterase superfamily K19222 - 3.1.2.28 0.000000000000000000000000000000000000000000000000000000377 198.0
HKD3_k127_8824150_2 acyl-CoA dehydrogenase K20035 - - 5.281e-200 641.0
HKD3_k127_8824150_20 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000313 206.0
HKD3_k127_8824150_21 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.00000000000000000000000000000000000000000000006084 181.0
HKD3_k127_8824150_22 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000001414 169.0
HKD3_k127_8824150_23 Amidinotransferase - - - 0.00000000000000000000000000000000000006015 156.0
HKD3_k127_8824150_24 OmpA-like transmembrane domain - - - 0.0000000000000000000000000000003357 135.0
HKD3_k127_8824150_25 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000001138 124.0
HKD3_k127_8824150_26 AsnC family transcriptional regulator - - - 0.00000000000000000000000003724 111.0
HKD3_k127_8824150_27 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.000000000000000004747 91.0
HKD3_k127_8824150_28 response regulator receiver K13599 - - 0.0000000000000002691 80.0
HKD3_k127_8824150_29 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000006996 71.0
HKD3_k127_8824150_3 Protein of unknown function (DUF1329) - - - 5.034e-197 623.0
HKD3_k127_8824150_4 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 393.0
HKD3_k127_8824150_5 Peptidase family M20/M25/M40 K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 355.0
HKD3_k127_8824150_6 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 319.0
HKD3_k127_8824150_7 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 328.0
HKD3_k127_8824150_8 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 317.0
HKD3_k127_8824150_9 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 313.0
HKD3_k127_8860536_0 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009126 569.0
HKD3_k127_8860536_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 526.0
HKD3_k127_8860536_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 496.0
HKD3_k127_8860536_3 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 427.0
HKD3_k127_8860536_4 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 346.0
HKD3_k127_8860536_5 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000001905 155.0
HKD3_k127_8860536_6 META domain K09914 - - 0.0000000000000000000000000006758 122.0
HKD3_k127_8860536_7 cyclic nucleotide binding K10914 - - 0.000000000000000000003298 99.0
HKD3_k127_8860536_8 Aldehyde dehydrogenase K00128,K00130 GO:0006950,GO:0008150,GO:0009636,GO:0009987,GO:0033554,GO:0042221,GO:0050896,GO:0051410,GO:0051716,GO:0070458,GO:0070887,GO:0097237,GO:0098754,GO:1901698,GO:1990748 1.2.1.3,1.2.1.8 0.000000000000000001918 85.0
HKD3_k127_8860536_9 Fels-1 Prophage Protein-like - - - 0.000003178 56.0
HKD3_k127_8882497_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1431.0
HKD3_k127_8882497_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1253.0
HKD3_k127_8882497_10 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 609.0
HKD3_k127_8882497_11 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 511.0
HKD3_k127_8882497_12 Alanine-glyoxylate amino-transferase K14261,K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 526.0
HKD3_k127_8882497_13 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 481.0
HKD3_k127_8882497_14 CHAT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 507.0
HKD3_k127_8882497_15 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008224 466.0
HKD3_k127_8882497_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 461.0
HKD3_k127_8882497_17 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 460.0
HKD3_k127_8882497_18 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 436.0
HKD3_k127_8882497_19 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003432 452.0
HKD3_k127_8882497_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 3.651e-310 961.0
HKD3_k127_8882497_20 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 443.0
HKD3_k127_8882497_21 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 436.0
HKD3_k127_8882497_22 Belongs to the transferase hexapeptide repeat family K00674 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008666,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016749,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 424.0
HKD3_k127_8882497_23 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 422.0
HKD3_k127_8882497_24 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 396.0
HKD3_k127_8882497_25 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 395.0
HKD3_k127_8882497_26 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 388.0
HKD3_k127_8882497_27 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005401 387.0
HKD3_k127_8882497_28 Binding-protein-dependent transport system inner membrane component K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 370.0
HKD3_k127_8882497_29 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 370.0
HKD3_k127_8882497_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 9.907e-295 914.0
HKD3_k127_8882497_30 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 358.0
HKD3_k127_8882497_31 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 345.0
HKD3_k127_8882497_32 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 350.0
HKD3_k127_8882497_33 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 345.0
HKD3_k127_8882497_34 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 337.0
HKD3_k127_8882497_35 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 332.0
HKD3_k127_8882497_36 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 333.0
HKD3_k127_8882497_37 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 331.0
HKD3_k127_8882497_38 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 333.0
HKD3_k127_8882497_39 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 310.0
HKD3_k127_8882497_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008773,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0019538,GO:0019752,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0070569,GO:0071704,GO:0140096,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.59 4.254e-275 878.0
HKD3_k127_8882497_40 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 320.0
HKD3_k127_8882497_41 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 301.0
HKD3_k127_8882497_42 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 292.0
HKD3_k127_8882497_43 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002405 284.0
HKD3_k127_8882497_44 Drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003339 279.0
HKD3_k127_8882497_45 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001435 278.0
HKD3_k127_8882497_46 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000001897 268.0
HKD3_k127_8882497_47 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003871 250.0
HKD3_k127_8882497_48 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000002724 252.0
HKD3_k127_8882497_49 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000004581 254.0
HKD3_k127_8882497_5 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.346e-254 794.0
HKD3_k127_8882497_50 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
HKD3_k127_8882497_51 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000001663 241.0
HKD3_k127_8882497_52 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000004009 235.0
HKD3_k127_8882497_53 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000258 236.0
HKD3_k127_8882497_54 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000001696 233.0
HKD3_k127_8882497_55 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000007551 216.0
HKD3_k127_8882497_56 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000005559 216.0
HKD3_k127_8882497_57 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000006061 194.0
HKD3_k127_8882497_58 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000007885 216.0
HKD3_k127_8882497_59 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000000000000000002911 179.0
HKD3_k127_8882497_6 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.686e-220 693.0
HKD3_k127_8882497_60 Negative regulator of sigma E activity K03598 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0044464,GO:0045152 - 0.00000000000000000000000000000000000000000009691 178.0
HKD3_k127_8882497_61 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000008526 167.0
HKD3_k127_8882497_62 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000003268 171.0
HKD3_k127_8882497_63 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000007383 169.0
HKD3_k127_8882497_64 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000002834 155.0
HKD3_k127_8882497_65 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000001745 132.0
HKD3_k127_8882497_66 succinate dehydrogenase - - - 0.0000000000000000000000000000002612 130.0
HKD3_k127_8882497_67 protein conserved in bacteria - - - 0.000000000000000000000000000001623 132.0
HKD3_k127_8882497_68 succinate dehydrogenase K00241 - - 0.000000000000000000000000000006323 126.0
HKD3_k127_8882497_69 lipid-A-disaccharide synthase activity - - - 0.00000000000000000000000000007107 124.0
HKD3_k127_8882497_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.592e-201 663.0
HKD3_k127_8882497_70 Belongs to the skp family K06142 - - 0.0000000000000000000000000001616 122.0
HKD3_k127_8882497_71 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000004171 119.0
HKD3_k127_8882497_72 DNA-templated transcription, initiation K03088,K03091 - - 0.0000000000000000000000001049 115.0
HKD3_k127_8882497_73 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000001193 111.0
HKD3_k127_8882497_74 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000001385 103.0
HKD3_k127_8882497_76 DNA-templated transcription, initiation K03088,K03091 - - 0.0000000000000000000006006 104.0
HKD3_k127_8882497_77 Belongs to the UPF0434 family K09791 - - 0.0000000000000000007161 87.0
HKD3_k127_8882497_78 diguanylate cyclase - - - 0.00000000000000003562 92.0
HKD3_k127_8882497_79 - - - - 0.0000000000006774 73.0
HKD3_k127_8882497_8 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 609.0
HKD3_k127_8882497_80 Flavinator of succinate dehydrogenase K09159 - - 0.000000000001479 80.0
HKD3_k127_8882497_81 cell redox homeostasis K00384 - 1.8.1.9 0.000000000002391 71.0
HKD3_k127_8882497_82 Negative regulator of sigma E activity - - - 0.000000000009202 73.0
HKD3_k127_8882497_83 Protein of unknown function (DUF1674) - - - 0.00000000008223 66.0
HKD3_k127_8882497_84 Carboxymuconolactone decarboxylase family - - - 0.0000000002727 63.0
HKD3_k127_8882497_85 Domain of unknown function (DUF4845) - - - 0.0000000002739 66.0
HKD3_k127_8882497_86 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000351 54.0
HKD3_k127_8882497_9 COG0608 Single-stranded DNA-specific exonuclease K07462 GO:0003674,GO:0003824,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008297,GO:0008409,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0033554,GO:0034641,GO:0035312,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0045145,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 610.0
HKD3_k127_9166835_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 0.0 1383.0
HKD3_k127_9166835_1 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 - 5.4.2.2 4.335e-237 756.0
HKD3_k127_9166835_10 - - - - 0.00000000000003016 79.0
HKD3_k127_9166835_2 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 516.0
HKD3_k127_9166835_3 beta-keto acid cleavage enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 340.0
HKD3_k127_9166835_4 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 332.0
HKD3_k127_9166835_5 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000003039 238.0
HKD3_k127_9166835_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000007604 193.0
HKD3_k127_9166835_7 Glycosyl hydrolases family 15 - - - 0.0000000000000000000000000000000000000000009002 171.0
HKD3_k127_9166835_8 Cupredoxin-like domain - - - 0.000000000000000000000000000000002255 132.0
HKD3_k127_9166835_9 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.000000000000009981 78.0
HKD3_k127_9206199_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 453.0
HKD3_k127_9206199_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 343.0
HKD3_k127_9206199_2 PFAM YicC-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 296.0
HKD3_k127_9206199_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046983,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000002974 245.0
HKD3_k127_9206199_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000002077 191.0
HKD3_k127_9206199_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000006186 185.0
HKD3_k127_9206199_6 protein involved in outer membrane biogenesis K07290 - - 0.000000009807 65.0
HKD3_k127_9206199_7 Binds the 23S rRNA K02909 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000001357 52.0
HKD3_k127_9206199_8 RNA-DNA hybrid ribonuclease activity - - - 0.0005371 47.0
HKD3_k127_9489082_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 2.574e-226 725.0
HKD3_k127_9489082_1 Melibiase K07407 - 3.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 594.0
HKD3_k127_9511170_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 427.0
HKD3_k127_9511170_1 aldehyde dehydrogenase (NAD) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 429.0
HKD3_k127_9511170_10 lipolytic protein G-D-S-L family - - - 0.000000000000000000002984 102.0
HKD3_k127_9511170_11 Tetratricopeptide repeat - - - 0.000000000000000001928 101.0
HKD3_k127_9511170_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 310.0
HKD3_k127_9511170_3 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 299.0
HKD3_k127_9511170_4 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006665 311.0
HKD3_k127_9511170_5 Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001969 281.0
HKD3_k127_9511170_6 PFAM Mandelate racemase muconate lactonizing K19802 GO:0003674,GO:0003824,GO:0016853,GO:0016854,GO:0016855 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004547 276.0
HKD3_k127_9511170_7 gluconate 5-dehydrogenase K00034,K00046,K00059,K00216 - 1.1.1.100,1.1.1.47,1.1.1.69,1.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000005182 243.0
HKD3_k127_9511170_8 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000004273 199.0
HKD3_k127_9511170_9 EamA-like transporter family - - - 0.00000000000000000000000003608 120.0
HKD3_k127_9524992_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 7.089e-277 862.0
HKD3_k127_9524992_1 Site-specific recombinase - - - 4.919e-261 820.0
HKD3_k127_9524992_10 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000005542 201.0
HKD3_k127_9524992_11 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000003256 177.0
HKD3_k127_9524992_12 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000008672 169.0
HKD3_k127_9524992_13 Protein of unknown function (DUF3300) - - - 0.00000000000000000000000000000000000000001577 173.0
HKD3_k127_9524992_14 MAPEG family - - - 0.00000000000000000000000000000000000001737 158.0
HKD3_k127_9524992_15 PRC-barrel domain - - - 0.0000000000000000000000000000000002173 136.0
HKD3_k127_9524992_16 Transglycosylase associated protein - - - 0.0000000000000000000000000000000007026 136.0
HKD3_k127_9524992_17 DNA polymerase Ligase (LigD) K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000003796 66.0
HKD3_k127_9524992_18 electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity - - - 0.000001096 54.0
HKD3_k127_9524992_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.287e-226 738.0
HKD3_k127_9524992_3 glycyl-tRNA synthetase, alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 514.0
HKD3_k127_9524992_4 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 447.0
HKD3_k127_9524992_5 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004666 290.0
HKD3_k127_9524992_6 Flagellar basal body rod K02396 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005751 273.0
HKD3_k127_9524992_7 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000001397 243.0
HKD3_k127_9524992_8 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000003671 239.0
HKD3_k127_9524992_9 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000002128 209.0