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Overview

ID MAG01926
Name HSJS2_bin.30
Sample SMP0050
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Pseudomonadales
Family Alcanivoracaceae
Genus JARGPN01
Species
Assembly information
Completeness (%) 87.69
Contamination (%) 4.36
GC content (%) 52.0
N50 (bp) 7,856
Genome size (bp) 3,008,565

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2788

Gene name Description KEGG GOs EC E-value Score Sequence
HSJS2_k127_1025137_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 533.0
HSJS2_k127_1027130_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 3.749e-278 880.0
HSJS2_k127_1027130_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 470.0
HSJS2_k127_1027130_2 Concanavalin A-like lectin/glucanases superfamily - - - 0.0000000000000000003013 91.0
HSJS2_k127_1036342_0 ATPase, AAA K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 452.0
HSJS2_k127_1036342_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 444.0
HSJS2_k127_1036342_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 433.0
HSJS2_k127_1036342_3 Domain of unknown function (DUF4350) - - - 0.0000000000000000000000000000000000000000000000000000000005291 219.0
HSJS2_k127_1036342_5 Dystroglycan-type cadherin domain protein K11005 - - 0.000000000000000000000005449 105.0
HSJS2_k127_1036342_6 - - - - 0.00005664 49.0
HSJS2_k127_1048668_0 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 449.0
HSJS2_k127_1048668_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000005247 184.0
HSJS2_k127_1050811_0 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation K00322 - 1.6.1.1 1.421e-219 689.0
HSJS2_k127_1050811_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 608.0
HSJS2_k127_1050811_3 ( 3 oxidation state) methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 479.0
HSJS2_k127_1050811_4 START domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003788 245.0
HSJS2_k127_1050811_5 protein conserved in bacteria K09938 - - 0.00000000000000000000000000000000000000000000000000000000006222 219.0
HSJS2_k127_1050811_6 Belongs to the DnaA family. HdA subfamily K10763 - - 0.00000000000000000000000000000000000000000000000000000001189 206.0
HSJS2_k127_1050811_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001383 200.0
HSJS2_k127_1050811_8 Pilus assembly protein PilZ - - - 0.000001699 55.0
HSJS2_k127_1054210_0 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 514.0
HSJS2_k127_1054210_1 ABC-type metal ion transport system, periplasmic component surface adhesin K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 311.0
HSJS2_k127_1054210_2 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000003188 239.0
HSJS2_k127_1054210_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000001634 127.0
HSJS2_k127_1054210_4 Outer membrane protein beta-barrel domain - - - 0.0000002191 54.0
HSJS2_k127_105966_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 9.512e-298 930.0
HSJS2_k127_105966_1 Histidine kinase - - - 4.955e-226 726.0
HSJS2_k127_105966_2 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 529.0
HSJS2_k127_105966_3 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 334.0
HSJS2_k127_105966_4 Antibiotic biosynthesis monooxygenase - GO:0003674,GO:0003824 - 0.000000000000000000000000000000000000000004905 157.0
HSJS2_k127_1060160_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 7.945e-290 895.0
HSJS2_k127_1060160_1 Histidine kinase K20972,K20973 - 2.7.13.3 3.058e-222 721.0
HSJS2_k127_1060160_10 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000003523 223.0
HSJS2_k127_1060160_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000003536 193.0
HSJS2_k127_1060160_12 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.00000000000000000000000000000000000000001797 155.0
HSJS2_k127_1060160_13 PFAM Chorismate mutase, type II K04782 - 4.2.99.21 0.0000000000000000000000000000002566 125.0
HSJS2_k127_1060160_2 Belongs to the GARS family K01945 - 6.3.4.13 5.855e-220 688.0
HSJS2_k127_1060160_3 COG0464 ATPases of the AAA class - - - 2.837e-216 681.0
HSJS2_k127_1060160_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 506.0
HSJS2_k127_1060160_5 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007976 484.0
HSJS2_k127_1060160_6 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 397.0
HSJS2_k127_1060160_7 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 338.0
HSJS2_k127_1060160_8 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 329.0
HSJS2_k127_1060160_9 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 298.0
HSJS2_k127_1067682_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 463.0
HSJS2_k127_1067682_1 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 402.0
HSJS2_k127_1067682_2 Belongs to the phosphatidylserine decarboxylase family. PSD-B subfamily. Prokaryotic type I sub-subfamily K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 359.0
HSJS2_k127_1067682_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004383 250.0
HSJS2_k127_107182_0 chemotaxis protein K02660 - - 6.489e-284 884.0
HSJS2_k127_107182_1 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 540.0
HSJS2_k127_107182_2 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001219 273.0
HSJS2_k127_107182_3 response regulator K02657 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007092 241.0
HSJS2_k127_107182_4 Chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
HSJS2_k127_107182_5 COG0784 FOG CheY-like receiver K02658 - - 0.0000000000000000000000000000000000000000000000000000000000000000007143 228.0
HSJS2_k127_107613_0 COG3264 Small-conductance mechanosensitive channel K05802 - - 5.642e-243 790.0
HSJS2_k127_107613_1 COG3000 Sterol desaturase K00227 - 1.14.19.20 5.566e-195 613.0
HSJS2_k127_107613_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 606.0
HSJS2_k127_107613_3 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002859 281.0
HSJS2_k127_107613_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000002127 240.0
HSJS2_k127_107613_5 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.0000000000000000000000303 107.0
HSJS2_k127_1080521_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1118.0
HSJS2_k127_1080521_1 Ketosteroid isomerase-related protein - - - 0.00000009561 53.0
HSJS2_k127_1082895_0 Secretory lipase - - - 5.649e-255 799.0
HSJS2_k127_1082895_1 fatty acid desaturase K00508 - 1.14.19.3 3.606e-227 707.0
HSJS2_k127_1082895_2 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 - - - 4.367e-210 656.0
HSJS2_k127_1082895_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 537.0
HSJS2_k127_1082895_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
HSJS2_k127_1082895_5 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 291.0
HSJS2_k127_1082895_6 Receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001495 263.0
HSJS2_k127_1082895_7 YecR-like lipoprotein - - - 0.0000000000000000000000000000000103 128.0
HSJS2_k127_1082895_8 - - - - 0.00000000000000000000000003815 117.0
HSJS2_k127_1082895_9 desaturase K00507 - 1.14.19.1 0.0002356 43.0
HSJS2_k127_1099573_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000001898 217.0
HSJS2_k127_1099573_1 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000004288 180.0
HSJS2_k127_1099573_2 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000001128 158.0
HSJS2_k127_1099573_4 positive regulation of growth rate - - - 0.00000002724 61.0
HSJS2_k127_1103139_0 PFAM aspartate glutamate uridylate kinase K00931,K03430,K06981 - 2.6.1.37,2.7.2.11,2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 455.0
HSJS2_k127_1103139_1 transport system, permease component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 323.0
HSJS2_k127_1103139_2 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 325.0
HSJS2_k127_1103139_3 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0099133,GO:1901265,GO:1901363 3.6.3.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 321.0
HSJS2_k127_1103139_4 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000002098 208.0
HSJS2_k127_1103139_5 molybdenum ABC transporter, periplasmic K02020 - - 0.0000000000000000000000000000000000000000000000000002144 194.0
HSJS2_k127_1104325_0 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 0.0 1038.0
HSJS2_k127_1104325_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007,K21787 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 2.371e-315 991.0
HSJS2_k127_1104325_2 exporters of the RND superfamily K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 442.0
HSJS2_k127_1104325_3 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 317.0
HSJS2_k127_1104325_4 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 312.0
HSJS2_k127_1104325_5 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.000000000000000009543 93.0
HSJS2_k127_1105018_0 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 346.0
HSJS2_k127_1105018_1 Glutathione-dependent formaldehyde-activating GFA - - - 0.000000000000000000000000000000000000000000000000000000001975 202.0
HSJS2_k127_1105018_2 - - - - 0.0000000000000000000000000000000000000000000000000000576 189.0
HSJS2_k127_1105018_3 - - - - 0.0000000000000000000000000000000000001952 146.0
HSJS2_k127_1105018_4 transcriptional regulator - - - 0.000000000000000000000000114 108.0
HSJS2_k127_1105018_5 - - - - 0.000000000000005486 76.0
HSJS2_k127_1105018_6 - - - - 0.0000000000001756 72.0
HSJS2_k127_112077_0 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 542.0
HSJS2_k127_112077_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 541.0
HSJS2_k127_112077_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000002974 175.0
HSJS2_k127_112077_3 unusual protein kinase - - - 0.000000000000000000000000000000000000000000001083 167.0
HSJS2_k127_1126721_0 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 569.0
HSJS2_k127_1126721_1 PFAM ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 482.0
HSJS2_k127_1126721_10 - - - - 0.00000000000000000000000000000003568 138.0
HSJS2_k127_1126721_2 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 436.0
HSJS2_k127_1126721_3 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 378.0
HSJS2_k127_1126721_4 KR domain - - - 0.000000000000000000000000000000000000000000000000000000003501 209.0
HSJS2_k127_1126721_5 Belongs to the UPF0225 family K09858 - - 0.000000000000000000000000000000000000000000000003273 177.0
HSJS2_k127_1126721_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000001403 179.0
HSJS2_k127_1126721_7 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000002882 170.0
HSJS2_k127_1126721_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000005453 154.0
HSJS2_k127_1126721_9 Cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000006376 130.0
HSJS2_k127_1129052_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 388.0
HSJS2_k127_1129052_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000001758 226.0
HSJS2_k127_1135189_0 Histidine kinase K20972 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 621.0
HSJS2_k127_1135189_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 546.0
HSJS2_k127_1135189_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 546.0
HSJS2_k127_1135189_3 desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 494.0
HSJS2_k127_1135189_4 Acyl dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 434.0
HSJS2_k127_1135189_5 desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 422.0
HSJS2_k127_1135189_6 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008447 282.0
HSJS2_k127_1135189_7 transcriptional regulator K22105 - - 0.0000000000000000000000000000188 121.0
HSJS2_k127_1138643_0 transcriptional regulator K13633 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 419.0
HSJS2_k127_1138643_1 Dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000523 384.0
HSJS2_k127_1138643_2 Domain of unknown function (DUF4136) - - - 0.00000000000008792 76.0
HSJS2_k127_1141938_0 Belongs to the UPF0176 family K07146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002452 276.0
HSJS2_k127_1141938_1 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000000000000003384 125.0
HSJS2_k127_1143292_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 8.661e-299 925.0
HSJS2_k127_1143292_1 NADH dehydrogenase K03885 - 1.6.99.3 6.191e-203 639.0
HSJS2_k127_1143292_10 COG0784 FOG CheY-like receiver K02658 - - 0.000000000000000000000000000000000000000000000000000000000002929 210.0
HSJS2_k127_1143292_11 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000001351 141.0
HSJS2_k127_1143292_2 accessory protein K06959 - - 5.47e-198 622.0
HSJS2_k127_1143292_3 Histidine kinase K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 546.0
HSJS2_k127_1143292_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 403.0
HSJS2_k127_1143292_5 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
HSJS2_k127_1143292_6 nucleotidase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 345.0
HSJS2_k127_1143292_7 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 343.0
HSJS2_k127_1143292_8 hydrolase K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 300.0
HSJS2_k127_1143292_9 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K08312 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 288.0
HSJS2_k127_114483_0 2OG-Fe(II) oxygenase K07394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
HSJS2_k127_114483_1 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006533 261.0
HSJS2_k127_114483_2 - - - - 0.000000000000000000000000000000000000000000000000000000007073 206.0
HSJS2_k127_114483_3 HNH endonuclease - - - 0.00000000000000000000000001623 117.0
HSJS2_k127_1146497_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 1.838e-231 723.0
HSJS2_k127_1146497_1 Ammonium transporter K03320 - - 1.871e-228 713.0
HSJS2_k127_1146497_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008142 281.0
HSJS2_k127_1146497_3 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000009042 190.0
HSJS2_k127_1146497_4 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000002149 65.0
HSJS2_k127_114847_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002728 526.0
HSJS2_k127_114847_1 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 431.0
HSJS2_k127_114847_2 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 374.0
HSJS2_k127_114847_3 flavoprotein involved in K transport - - - 0.000000000000003576 77.0
HSJS2_k127_1149541_0 Polysaccharide biosynthesis protein - - - 7.634e-216 685.0
HSJS2_k127_1149541_1 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 612.0
HSJS2_k127_1175040_0 transport system, large permease component - - - 0.0 1011.0
HSJS2_k127_1175040_1 unusual protein kinase - - - 4.555e-215 676.0
HSJS2_k127_1175040_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 520.0
HSJS2_k127_1175040_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 463.0
HSJS2_k127_1175040_4 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000008294 65.0
HSJS2_k127_1188095_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 613.0
HSJS2_k127_1188095_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 321.0
HSJS2_k127_1188095_2 COG0642 Signal transduction histidine kinase K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000008649 205.0
HSJS2_k127_1188095_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000538 94.0
HSJS2_k127_1227689_0 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 333.0
HSJS2_k127_1227689_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000004187 208.0
HSJS2_k127_1227689_2 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000000000000000005426 180.0
HSJS2_k127_1227689_3 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00002068 48.0
HSJS2_k127_1228665_0 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 563.0
HSJS2_k127_1228665_1 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.00000000000000000000469 101.0
HSJS2_k127_1236086_0 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009032 437.0
HSJS2_k127_1236086_1 Flavin-binding monooxygenase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004801 417.0
HSJS2_k127_1236086_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007653 272.0
HSJS2_k127_1236086_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K10936,K16079 - - 0.0000004895 55.0
HSJS2_k127_124294_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 1.027e-237 743.0
HSJS2_k127_124294_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.296e-198 623.0
HSJS2_k127_124294_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 552.0
HSJS2_k127_124294_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 508.0
HSJS2_k127_124294_4 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 448.0
HSJS2_k127_124294_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 418.0
HSJS2_k127_124294_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 411.0
HSJS2_k127_124294_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000937 286.0
HSJS2_k127_124294_8 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000002964 147.0
HSJS2_k127_1248890_0 Oligopeptidase K01414 - 3.4.24.70 0.0 1055.0
HSJS2_k127_1248890_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 2.715e-248 785.0
HSJS2_k127_1248890_10 nucleic-acid-binding protein containing a Zn-ribbon domain K07070 - - 0.0000000000000000003967 91.0
HSJS2_k127_1248890_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0003824,GO:0004109,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016634,GO:0018130,GO:0019438,GO:0030145,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046906,GO:0046914,GO:0046983,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 509.0
HSJS2_k127_1248890_3 transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 433.0
HSJS2_k127_1248890_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 366.0
HSJS2_k127_1248890_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 294.0
HSJS2_k127_1248890_6 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.000000000000000000000000000000000000000000000000000000000000004581 219.0
HSJS2_k127_1248890_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-) CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000003546 186.0
HSJS2_k127_1248890_8 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.0000000000000000000000000000000000000000000135 167.0
HSJS2_k127_1248890_9 Gaf domain K01768,K17763 - 4.6.1.1 0.000000000000000000000000000000002383 133.0
HSJS2_k127_1253420_0 TonB dependent receptor - - - 1.636e-208 670.0
HSJS2_k127_1253420_1 diguanylate cyclase - - - 0.00000000000000246 81.0
HSJS2_k127_1253978_0 Flavin-binding monooxygenase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 529.0
HSJS2_k127_1253978_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 434.0
HSJS2_k127_1255192_0 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 494.0
HSJS2_k127_1255192_1 hydrolase of alkaline phosphatase superfamily K07014 - - 0.0000000000000000000000000000000000000000001154 162.0
HSJS2_k127_1255691_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 7.942e-195 614.0
HSJS2_k127_1255691_1 metal-sulfur cluster biosynthetic enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007695 278.0
HSJS2_k127_1255691_2 Fe-S metabolism associated domain - - - 0.000000000000000000000000000000000000000000000000000193 190.0
HSJS2_k127_1255691_3 Belongs to the HesB IscA family K05997,K13628 - - 0.00000000000000000000000000000000006097 136.0
HSJS2_k127_1255691_4 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component K09015 - - 0.00000002091 59.0
HSJS2_k127_1255691_5 Metallo-beta-lactamase superfamily - - - 0.000001727 54.0
HSJS2_k127_1263115_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 2.888e-204 647.0
HSJS2_k127_1263115_1 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006174 511.0
HSJS2_k127_1263115_2 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 303.0
HSJS2_k127_1263115_3 Lipase chaperone - - - 0.000000000000000000000000000000000000000000000000000000000000000001198 241.0
HSJS2_k127_126372_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 0.0 1002.0
HSJS2_k127_126372_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 1.393e-195 619.0
HSJS2_k127_126372_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001702 232.0
HSJS2_k127_126372_11 oxidase assembly K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000587 218.0
HSJS2_k127_126372_12 signal sequence binding - - - 0.000000000000000000000000000000000000000000000000000003601 198.0
HSJS2_k127_126372_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000002646 176.0
HSJS2_k127_126372_2 diguanylate cyclase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 603.0
HSJS2_k127_126372_3 protein required for cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 496.0
HSJS2_k127_126372_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 484.0
HSJS2_k127_126372_5 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009679 446.0
HSJS2_k127_126372_6 COG0501 Zn-dependent protease with chaperone function - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 436.0
HSJS2_k127_126372_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 381.0
HSJS2_k127_126372_8 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008044 280.0
HSJS2_k127_126372_9 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000016 244.0
HSJS2_k127_1272975_0 Peroxiredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 421.0
HSJS2_k127_1272975_1 COG0517 FOG CBS domain - - - 0.000000000000000000000000000000000000000000000000002737 186.0
HSJS2_k127_1272975_2 Trypsin-like serine protease - - - 0.00000003094 61.0
HSJS2_k127_1285831_0 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 1.066e-292 917.0
HSJS2_k127_1296881_0 Molecular chaperone. Has ATPase activity K04079 - - 3.148e-267 836.0
HSJS2_k127_1296881_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.498e-204 646.0
HSJS2_k127_1296881_2 Pfam:HipA_N K07154 - 2.7.11.1 4.822e-196 619.0
HSJS2_k127_1296881_3 Carboxylesterase K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 316.0
HSJS2_k127_1296881_4 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000001654 158.0
HSJS2_k127_1296881_5 sequence-specific DNA binding - - - 0.00000000000000000000005749 102.0
HSJS2_k127_1298621_0 Transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006796 362.0
HSJS2_k127_1298621_1 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 298.0
HSJS2_k127_1316464_0 Part of a membrane complex involved in electron transport K03615 - - 1.356e-298 944.0
HSJS2_k127_1316464_1 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 614.0
HSJS2_k127_1316464_10 Thioredoxin K03671 - - 0.0000000000000000000000002482 108.0
HSJS2_k127_1316464_2 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 571.0
HSJS2_k127_1316464_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008328 532.0
HSJS2_k127_1316464_4 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 520.0
HSJS2_k127_1316464_5 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 376.0
HSJS2_k127_1316464_6 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003356 343.0
HSJS2_k127_1316464_7 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 331.0
HSJS2_k127_1316464_8 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000000000000000000000000000000000000000001029 219.0
HSJS2_k127_1316464_9 Protein of unknown function (DUF3301) - - - 0.00000000000000000000000005325 111.0
HSJS2_k127_1317800_0 COG1960 Acyl-CoA dehydrogenases K06445 - - 6.584e-307 947.0
HSJS2_k127_1317800_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 416.0
HSJS2_k127_1318857_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 5.451e-265 824.0
HSJS2_k127_1318857_1 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000001171 214.0
HSJS2_k127_133246_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1060.0
HSJS2_k127_133246_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.137e-242 755.0
HSJS2_k127_133246_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 610.0
HSJS2_k127_133246_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 449.0
HSJS2_k127_133246_4 Histidine kinase K10916 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 406.0
HSJS2_k127_133246_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 333.0
HSJS2_k127_133246_6 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001259 287.0
HSJS2_k127_133246_7 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004857 252.0
HSJS2_k127_133246_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000000000000000000003864 227.0
HSJS2_k127_1333614_0 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 1.408e-202 636.0
HSJS2_k127_1333614_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 3.882e-195 615.0
HSJS2_k127_1333614_10 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000000000000000000000009137 185.0
HSJS2_k127_1333614_11 - - - - 0.0000000000000000000001019 100.0
HSJS2_k127_1333614_12 - - - - 0.000009607 47.0
HSJS2_k127_1333614_2 Alkaline phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 556.0
HSJS2_k127_1333614_3 Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 512.0
HSJS2_k127_1333614_4 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 385.0
HSJS2_k127_1333614_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000001346 242.0
HSJS2_k127_1333614_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000007975 218.0
HSJS2_k127_1333614_7 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000006449 188.0
HSJS2_k127_1333614_8 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000000006863 184.0
HSJS2_k127_1333614_9 iron-sulfur cluster insertion protein erpA K15724 - - 0.0000000000000000000000000000000000000000000000002632 178.0
HSJS2_k127_134361_0 hydrolase of alkaline phosphatase superfamily K07014 - - 4.488e-195 625.0
HSJS2_k127_134361_1 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 469.0
HSJS2_k127_134361_2 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000000000001641 109.0
HSJS2_k127_1343782_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1579.0
HSJS2_k127_1343782_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins K03528 - - 0.000000000000000000000000000000000000006588 153.0
HSJS2_k127_1343782_2 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.00000000000000000000000000001376 121.0
HSJS2_k127_1362216_0 Alpha beta hydrolase - - - 0.0000000001375 61.0
HSJS2_k127_1365909_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1130.0
HSJS2_k127_1365909_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 507.0
HSJS2_k127_1365909_2 Nucleoside triphosphate K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000003132 164.0
HSJS2_k127_1368614_0 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000004812 221.0
HSJS2_k127_1368614_1 MAPEG family - - - 0.0000000000000000000000000000005625 126.0
HSJS2_k127_1369092_0 exporters of the RND superfamily K07003 - - 0.000000000000000000000000000000000000000000000002248 184.0
HSJS2_k127_1369092_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000001948 139.0
HSJS2_k127_1374159_0 aminopeptidase N K01256 - 3.4.11.2 1.495e-318 994.0
HSJS2_k127_1374159_1 Protein of unknown function (DUF1302) - - - 1.738e-256 805.0
HSJS2_k127_1383497_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 374.0
HSJS2_k127_1383497_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 302.0
HSJS2_k127_1383497_2 membrane protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000003356 223.0
HSJS2_k127_1383497_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000112 196.0
HSJS2_k127_1383497_4 membrane - - - 0.000000000000000000000000143 110.0
HSJS2_k127_139605_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 3.318e-217 680.0
HSJS2_k127_139605_1 COG0038 Chloride channel protein EriC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007828 597.0
HSJS2_k127_139605_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 468.0
HSJS2_k127_139605_3 phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 301.0
HSJS2_k127_139605_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000001607 242.0
HSJS2_k127_139605_5 membrane K08973 - - 0.00000000000000000000000000000000000000000000000000000000000000000004466 234.0
HSJS2_k127_1397299_0 Cytochrome c-type biogenesis protein K02198 - - 3.371e-289 901.0
HSJS2_k127_1397299_1 catalyzes a condensation reaction in fatty acid biosynthesis addition of an acyl acceptor of two carbons from malonyl-ACP K00647 - 2.3.1.41 1.298e-208 653.0
HSJS2_k127_1397299_2 COG3203 Outer membrane protein (porin) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 409.0
HSJS2_k127_1397299_3 COG3203 Outer membrane protein (porin) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 340.0
HSJS2_k127_1397299_4 Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length K01716 - 4.2.1.59,5.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 291.0
HSJS2_k127_1397299_5 Thiol disulfide interchange protein K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000028 250.0
HSJS2_k127_1397299_6 pyrophosphohydrolase K04765 - 3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000005204 221.0
HSJS2_k127_1397299_7 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000001038 149.0
HSJS2_k127_1401355_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 467.0
HSJS2_k127_1401355_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
HSJS2_k127_1401355_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008992 241.0
HSJS2_k127_1401355_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000004052 219.0
HSJS2_k127_1401355_4 Histidine kinase - - - 0.000000000000000000000000000000000001069 152.0
HSJS2_k127_1401355_5 Uncharacterised protein family (UPF0270) K09898 - - 0.0000000000000002364 81.0
HSJS2_k127_1405467_1 regulator of chromosome condensation, RCC1 - - - 0.000000002575 70.0
HSJS2_k127_1408654_0 flavoprotein involved in K transport - - - 1.483e-202 644.0
HSJS2_k127_1408654_1 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 553.0
HSJS2_k127_1408654_2 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 451.0
HSJS2_k127_1408654_3 Metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 447.0
HSJS2_k127_1408654_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 390.0
HSJS2_k127_1408654_5 esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 377.0
HSJS2_k127_1408654_6 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000001438 168.0
HSJS2_k127_1408654_7 - - - - 0.0000000000000000000000000000000000000000002363 160.0
HSJS2_k127_1408654_8 mRNA catabolic process - - - 0.00000000000000000000000001827 116.0
HSJS2_k127_142048_0 alanine symporter K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007318 495.0
HSJS2_k127_142048_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 377.0
HSJS2_k127_142048_2 macromolecule glycosylation - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000001988 78.0
HSJS2_k127_1425296_0 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 605.0
HSJS2_k127_1425296_1 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 344.0
HSJS2_k127_1425296_2 - - - - 0.000000000000008505 77.0
HSJS2_k127_1431206_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1122.0
HSJS2_k127_1431206_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.845e-202 636.0
HSJS2_k127_1431206_10 acetyltransferase - - - 0.0000000000000000000000000000000000000000000005535 171.0
HSJS2_k127_1431206_12 protein acetylation K02348 - - 0.0000000000000003729 85.0
HSJS2_k127_1431206_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 498.0
HSJS2_k127_1431206_3 Transcription factor K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 426.0
HSJS2_k127_1431206_4 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 420.0
HSJS2_k127_1431206_5 GGDEF domain K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 382.0
HSJS2_k127_1431206_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 362.0
HSJS2_k127_1431206_7 Pfam:UPF0118 - - - 0.0000000000000000000000000000000000000000000000000000000001461 207.0
HSJS2_k127_1431206_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000001052 196.0
HSJS2_k127_1431206_9 Belongs to the UPF0149 family K07039 - - 0.0000000000000000000000000000000000000000000000000000003344 200.0
HSJS2_k127_1433521_0 phenylacetate-CoA ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
HSJS2_k127_1433521_2 Psort location Cytoplasmic, score - - - 0.0000016 53.0
HSJS2_k127_1433521_3 OmpA-like transmembrane domain - - - 0.00005815 53.0
HSJS2_k127_1438879_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 3.397e-290 897.0
HSJS2_k127_1438879_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.16e-253 782.0
HSJS2_k127_1438879_10 protein conserved in bacteria K09948 - - 0.0000000000000000000000000000000000000005337 151.0
HSJS2_k127_1438879_11 - - - - 0.0000156 51.0
HSJS2_k127_1438879_2 Acyltransferase - GO:0000271,GO:0005575,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016020,GO:0016051,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 8.056e-208 664.0
HSJS2_k127_1438879_3 amino acid aldolase or racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 513.0
HSJS2_k127_1438879_4 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007818 490.0
HSJS2_k127_1438879_5 COG0277 FAD FMN-containing dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008411 495.0
HSJS2_k127_1438879_6 COG3555 Aspartyl asparaginyl beta-hydroxylase and related dioxygenases K12979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 431.0
HSJS2_k127_1438879_7 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 319.0
HSJS2_k127_1438879_8 Pyridoxal-phosphate dependent enzyme K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000003497 239.0
HSJS2_k127_1438879_9 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000000000000000005445 206.0
HSJS2_k127_1453740_0 Animal haem peroxidase - - - 0.0 1681.0
HSJS2_k127_1453740_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000009188 115.0
HSJS2_k127_1453740_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0004845 45.0
HSJS2_k127_1455382_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1892.0
HSJS2_k127_1455382_1 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01457 - 3.5.1.54 1.911e-264 827.0
HSJS2_k127_1455382_2 Thrombospondin type 3 repeat - - - 6.964e-201 651.0
HSJS2_k127_1455382_3 Domain of unknown function (DUF1989) K09967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 390.0
HSJS2_k127_1455382_4 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 383.0
HSJS2_k127_1455382_5 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 332.0
HSJS2_k127_1455382_6 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.00000000000003502 72.0
HSJS2_k127_1462884_0 Transglycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003831 253.0
HSJS2_k127_1462884_1 NlpE C-terminal OB domain - - - 0.0000000001306 69.0
HSJS2_k127_148405_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 602.0
HSJS2_k127_148405_1 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 471.0
HSJS2_k127_148405_2 ABC transporter ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 406.0
HSJS2_k127_148405_3 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000000000000000007366 224.0
HSJS2_k127_148405_4 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000000000002235 214.0
HSJS2_k127_148405_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000003443 158.0
HSJS2_k127_148405_6 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000000000376 123.0
HSJS2_k127_148405_7 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000003888 119.0
HSJS2_k127_148405_8 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.0000000000000000000000000000477 123.0
HSJS2_k127_152342_0 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 325.0
HSJS2_k127_152342_1 COG0084 Mg-dependent DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 318.0
HSJS2_k127_152342_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000001375 222.0
HSJS2_k127_152342_3 Universal stress protein K06149 - - 0.0000000000000000000000000000000000000000000000000000000701 198.0
HSJS2_k127_152342_4 protein conserved in bacteria - - - 0.00000000000000000000000000226 117.0
HSJS2_k127_152342_5 - - - - 0.0000000000005145 79.0
HSJS2_k127_152343_0 Helicase and RNase D C-terminal K03654 - 3.6.4.12 2.122e-275 858.0
HSJS2_k127_152343_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 1.353e-253 785.0
HSJS2_k127_152343_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 512.0
HSJS2_k127_152343_3 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 394.0
HSJS2_k127_152343_4 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 339.0
HSJS2_k127_152343_5 TIGRFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000001753 254.0
HSJS2_k127_152343_7 ABC-type phosphate transport system, periplasmic component - - - 0.00000000000000000000000000007636 121.0
HSJS2_k127_154060_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 593.0
HSJS2_k127_154060_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007172 270.0
HSJS2_k127_154060_2 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000347 228.0
HSJS2_k127_154060_3 Ribosomal protein L30 K02907 - - 0.000000000000000000000099 99.0
HSJS2_k127_1544392_0 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 8.65e-197 622.0
HSJS2_k127_1544392_1 Bile acid sodium symporter K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 354.0
HSJS2_k127_1544392_2 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 346.0
HSJS2_k127_1544392_3 COG0451 Nucleoside-diphosphate-sugar epimerases K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002387 257.0
HSJS2_k127_1544392_4 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000925 227.0
HSJS2_k127_1544392_5 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000001387 220.0
HSJS2_k127_1548255_0 Ompa motb domain protein - - - 0.0 2344.0
HSJS2_k127_1548255_1 GMC oxidoreductase K03333 - 1.1.3.6 1.075e-218 691.0
HSJS2_k127_1548255_2 transcriptional regulator K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
HSJS2_k127_1548255_3 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 351.0
HSJS2_k127_1548255_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000001981 217.0
HSJS2_k127_1548255_5 hydroperoxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000002816 203.0
HSJS2_k127_1548255_6 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000004626 133.0
HSJS2_k127_1548255_7 Domain of unknown function DUF11 - - - 0.00000001269 56.0
HSJS2_k127_1548255_8 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) - - - 0.00000005854 55.0
HSJS2_k127_155893_0 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 1.606e-223 696.0
HSJS2_k127_155893_1 COG1960 Acyl-CoA dehydrogenases - - - 7.527e-218 682.0
HSJS2_k127_155893_10 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000004982 93.0
HSJS2_k127_155893_11 cyclic nucleotide binding K10914 - - 0.00000000000000002935 88.0
HSJS2_k127_155893_2 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 385.0
HSJS2_k127_155893_3 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 340.0
HSJS2_k127_155893_4 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006251 320.0
HSJS2_k127_155893_5 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004386 268.0
HSJS2_k127_155893_6 1-acyl-sn-glycerol-3-phosphate acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000001314 257.0
HSJS2_k127_155893_7 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000005541 191.0
HSJS2_k127_155893_8 permease - - - 0.0000000000000000000000000000000000000002851 162.0
HSJS2_k127_155893_9 membrane protein (homolog of Drosophila rhomboid) K02441 - - 0.00000000000000000000000000000000001273 141.0
HSJS2_k127_156487_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005475 269.0
HSJS2_k127_156487_1 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007522 244.0
HSJS2_k127_156487_2 uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000315 213.0
HSJS2_k127_156487_3 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000000000000000000000000000000000000000000000000000000000152 206.0
HSJS2_k127_156487_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000009785 143.0
HSJS2_k127_1572349_0 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 436.0
HSJS2_k127_1572349_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006968 252.0
HSJS2_k127_1572349_2 HxlR-like helix-turn-helix - - - 0.00000000000000000000000000000000000000000000000000000000000000001095 227.0
HSJS2_k127_1572349_3 YecR-like lipoprotein - - - 0.00000000000000000000000000000000002032 137.0
HSJS2_k127_1572349_4 - - - - 0.0000000000000002369 81.0
HSJS2_k127_1586999_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 316.0
HSJS2_k127_1586999_1 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 295.0
HSJS2_k127_1586999_10 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001015 78.0
HSJS2_k127_1586999_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 291.0
HSJS2_k127_1586999_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000002755 232.0
HSJS2_k127_1586999_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000002141 207.0
HSJS2_k127_1586999_5 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000000000000000000000002432 184.0
HSJS2_k127_1586999_6 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000003328 174.0
HSJS2_k127_1586999_7 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000004859 154.0
HSJS2_k127_1586999_8 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000000000000000001309 148.0
HSJS2_k127_1586999_9 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000001026 95.0
HSJS2_k127_1597343_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 6.214e-254 803.0
HSJS2_k127_1597343_1 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 454.0
HSJS2_k127_1597343_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 384.0
HSJS2_k127_1597343_3 COG1226 Kef-type K transport systems K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 380.0
HSJS2_k127_1597343_4 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 307.0
HSJS2_k127_1597343_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002186 283.0
HSJS2_k127_1597343_6 Belongs to the DEAD box helicase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000312 283.0
HSJS2_k127_1597979_0 MATE efflux family protein K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 603.0
HSJS2_k127_1597979_1 COG0811 Biopolymer transport proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 326.0
HSJS2_k127_1597979_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 293.0
HSJS2_k127_1597979_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001622 270.0
HSJS2_k127_1597979_4 COG0848 Biopolymer transport protein - - - 0.00000000000000000000000000000000000000000000000000000000008887 208.0
HSJS2_k127_1597979_5 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000000000000000000000459 191.0
HSJS2_k127_1597979_6 protein conserved in bacteria K09906 - - 0.0000000000000000000000000000000000000000000003538 174.0
HSJS2_k127_1597979_7 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000009298 113.0
HSJS2_k127_1600109_0 LVIVD repeat - - - 0.0 1404.0
HSJS2_k127_1600109_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 383.0
HSJS2_k127_1606487_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 1.204e-231 729.0
HSJS2_k127_1606487_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 313.0
HSJS2_k127_1606487_2 Anti sigma-E protein RseA, N-terminal domain K03597 - - 0.000000000000000000000000000000000000000001231 164.0
HSJS2_k127_1606487_3 Negative regulator of sigma E activity K03598 - - 0.00000000000000000000000000000006544 130.0
HSJS2_k127_1611892_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.849e-290 907.0
HSJS2_k127_1611892_1 COG0642 Signal transduction histidine kinase - - - 1.508e-255 819.0
HSJS2_k127_1611892_10 transcriptional Regulator, LysR family - - - 0.0000000000000000000000000000000000000000000000000000000000009652 220.0
HSJS2_k127_1611892_11 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000008452 199.0
HSJS2_k127_1611892_12 transcriptional regulator - - - 0.000000000000000000000000000000000000000006429 161.0
HSJS2_k127_1611892_13 YaeQ - - - 0.000000000000000000000000000000009319 131.0
HSJS2_k127_1611892_14 Tautomerase enzyme K01821 - 5.3.2.6 0.00000000000000000000000001563 109.0
HSJS2_k127_1611892_15 Protein of unknown function (DUF2288) - - - 0.000000000000000000000001627 109.0
HSJS2_k127_1611892_16 endonuclease containing a URI domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000000000001062 103.0
HSJS2_k127_1611892_17 Protein of unknown function (DUF3301) - - - 0.0000000000001108 72.0
HSJS2_k127_1611892_2 dioxygenase K11159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 521.0
HSJS2_k127_1611892_3 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 528.0
HSJS2_k127_1611892_4 Esterase of the alpha-beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 490.0
HSJS2_k127_1611892_5 Peptidase_C39 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005511 439.0
HSJS2_k127_1611892_6 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 397.0
HSJS2_k127_1611892_7 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 329.0
HSJS2_k127_1611892_8 Glutathione S-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 298.0
HSJS2_k127_1611892_9 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 304.0
HSJS2_k127_1612702_0 Belongs to the UPF0061 (SELO) family K08997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 530.0
HSJS2_k127_1612702_1 Protein of unknown function (DUF2804) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 454.0
HSJS2_k127_1612702_2 Domain of unknown function (DUF4282) - - - 0.000000000000000000000000000000000000000000000000000000000788 206.0
HSJS2_k127_1612702_3 Transcriptional K10917 - - 0.00000000000000000000000000000000000000000169 162.0
HSJS2_k127_1612702_4 protein conserved in bacteria K09977 - - 0.0000000000000000000000000000000000002691 152.0
HSJS2_k127_1612702_5 Acetyl-CoA hydrolase - - - 0.000000000000000003686 87.0
HSJS2_k127_1612702_6 Protein of unknown function (DUF1524) - - - 0.00000000001735 71.0
HSJS2_k127_1617230_0 exporters of the RND superfamily K07003 - - 0.0 1011.0
HSJS2_k127_1617230_1 oxidoreductase - - - 1.38e-241 758.0
HSJS2_k127_1617230_10 Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway K08967 - 1.13.11.53,1.13.11.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000016 260.0
HSJS2_k127_1617230_11 Nucleoside-diphosphate-sugar epimerases - - - 0.00000000000000000000000000000000000000000000000000002392 196.0
HSJS2_k127_1617230_12 - - - - 0.00000000000000000000000000000000005898 139.0
HSJS2_k127_1617230_14 - - - - 0.000000000000000000000000000001145 123.0
HSJS2_k127_1617230_2 Histidine kinase K20973 - 2.7.13.3 2.67e-235 749.0
HSJS2_k127_1617230_3 COG2303 Choline dehydrogenase and related flavoproteins - - - 3.449e-225 710.0
HSJS2_k127_1617230_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 488.0
HSJS2_k127_1617230_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007894 366.0
HSJS2_k127_1617230_6 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964,K22130 - 4.1.1.104,4.2.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002382 283.0
HSJS2_k127_1617230_7 Bifunctional enzyme that catalyzes the enolization of 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK-MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK- MTPene) K09880 - 3.1.3.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006065 281.0
HSJS2_k127_1617230_8 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003071 260.0
HSJS2_k127_1625033_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 566.0
HSJS2_k127_1625033_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000001235 180.0
HSJS2_k127_1634280_0 Belongs to the RimK family K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 507.0
HSJS2_k127_1634280_1 Deacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 498.0
HSJS2_k127_1634280_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0003906,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0034644,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071214,GO:0071478,GO:0071482,GO:0071704,GO:0090304,GO:0104004,GO:0140097,GO:1901360 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 362.0
HSJS2_k127_1634280_3 carboxymethylenebutenolidase activity K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 346.0
HSJS2_k127_1634280_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 309.0
HSJS2_k127_1634280_5 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000002254 219.0
HSJS2_k127_1634280_6 protein conserved in archaea - - - 0.00000000000000000000000000000000000000000000000000000000000000684 218.0
HSJS2_k127_1634280_7 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000005858 181.0
HSJS2_k127_1634280_8 Thioredoxin K03671 - - 0.0000000000000002456 79.0
HSJS2_k127_1641381_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1067.0
HSJS2_k127_1641381_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000006165 184.0
HSJS2_k127_1645512_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1309.0
HSJS2_k127_1645512_1 GTP-binding protein TypA K06207 - - 0.0 1013.0
HSJS2_k127_1645512_10 Na -dependent transporter K03453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 363.0
HSJS2_k127_1645512_11 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 354.0
HSJS2_k127_1645512_12 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 340.0
HSJS2_k127_1645512_13 START domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006235 296.0
HSJS2_k127_1645512_14 protein conserved in bacteria K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003973 283.0
HSJS2_k127_1645512_15 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002527 288.0
HSJS2_k127_1645512_16 Belongs to the UPF0178 family K09768 - - 0.000000000000000000000000000000000000000000000000000000000003158 211.0
HSJS2_k127_1645512_17 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000007138 211.0
HSJS2_k127_1645512_18 - - - - 0.00000000000000000000000000000000000000000000000000000000003327 216.0
HSJS2_k127_1645512_19 Sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000005082 193.0
HSJS2_k127_1645512_2 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 614.0
HSJS2_k127_1645512_20 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000003374 191.0
HSJS2_k127_1645512_21 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000000000002041 185.0
HSJS2_k127_1645512_22 protein conserved in archaea - - - 0.0000000000000000000000000000000000000005692 157.0
HSJS2_k127_1645512_23 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000001403 122.0
HSJS2_k127_1645512_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 543.0
HSJS2_k127_1645512_4 COG0642 Signal transduction histidine kinase K20971 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 550.0
HSJS2_k127_1645512_5 protein involved in outer membrane biogenesis K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 518.0
HSJS2_k127_1645512_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 456.0
HSJS2_k127_1645512_7 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 434.0
HSJS2_k127_1645512_8 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007376 381.0
HSJS2_k127_1645512_9 Cobalt zinc cadmium efflux RND transporter outermembrane protein K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 374.0
HSJS2_k127_1652789_0 Pfam:DUF1446 - - - 2.132e-307 950.0
HSJS2_k127_1652789_1 Acetyl-CoA carboxylase K13778 - 6.4.1.5 8.23e-271 842.0
HSJS2_k127_1652789_2 acyl-CoA dehydrogenase K11731 - - 5.46e-230 715.0
HSJS2_k127_1652789_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 500.0
HSJS2_k127_1652789_4 enoyl-CoA hydratase K13779 - 4.2.1.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 387.0
HSJS2_k127_1652789_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000007431 183.0
HSJS2_k127_1652789_6 Biotin carboxylase C-terminal domain K13777 - 6.4.1.5 0.00000000000000000000000000000004442 128.0
HSJS2_k127_1653725_0 ATPase components of ABC transporters with duplicated ATPase domains - - - 1.369e-289 895.0
HSJS2_k127_1653725_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003692 552.0
HSJS2_k127_1653725_2 desaturase K00508 - 1.14.19.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 527.0
HSJS2_k127_1653725_3 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 485.0
HSJS2_k127_1653725_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 485.0
HSJS2_k127_1653725_5 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 362.0
HSJS2_k127_1653725_6 Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer K22105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003114 267.0
HSJS2_k127_1653725_7 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000000000000000000001093 192.0
HSJS2_k127_166149_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002422 267.0
HSJS2_k127_166149_1 - - - - 0.0000000000000000000000000000000000000000004095 166.0
HSJS2_k127_166149_2 Ammonium transporter K03320 - - 0.00000000000002253 74.0
HSJS2_k127_166149_3 Bacterial SH3 domain homologues - - - 0.00000008894 61.0
HSJS2_k127_1666866_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 484.0
HSJS2_k127_1666866_1 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000000000000000000000000000000006747 185.0
HSJS2_k127_1666866_2 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000002345 108.0
HSJS2_k127_1666866_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0002356 43.0
HSJS2_k127_1670080_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1611.0
HSJS2_k127_1670080_1 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 466.0
HSJS2_k127_1670080_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 389.0
HSJS2_k127_1670080_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 386.0
HSJS2_k127_1671598_0 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 607.0
HSJS2_k127_1671598_1 transporter K12942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 593.0
HSJS2_k127_1671598_10 COG1305 Transglutaminase-like enzymes K22452 - 2.3.2.13 0.0000000054 63.0
HSJS2_k127_1671598_2 (ABC) transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 458.0
HSJS2_k127_1671598_3 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 413.0
HSJS2_k127_1671598_4 Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 385.0
HSJS2_k127_1671598_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 356.0
HSJS2_k127_1671598_6 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 304.0
HSJS2_k127_1671598_7 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000003614 217.0
HSJS2_k127_1671598_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000003982 126.0
HSJS2_k127_1671598_9 - - - - 0.00000000002966 64.0
HSJS2_k127_1687985_0 Nitrate nitrite transporter K02575 - - 6.29e-230 724.0
HSJS2_k127_1687985_1 Serine Threonine protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 572.0
HSJS2_k127_1687985_2 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 561.0
HSJS2_k127_1690175_0 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000008891 202.0
HSJS2_k127_1696211_0 Transposase - - - 5.922e-196 621.0
HSJS2_k127_1696211_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 497.0
HSJS2_k127_1696211_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 331.0
HSJS2_k127_1696211_3 - - - - 0.00000000000000001564 84.0
HSJS2_k127_1700625_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004066 462.0
HSJS2_k127_1700625_1 membrane protein required for spore maturation in B.subtilis K06374 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 420.0
HSJS2_k127_1700625_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 413.0
HSJS2_k127_171061_0 exporters of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 577.0
HSJS2_k127_171061_1 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000000000002524 177.0
HSJS2_k127_1714768_0 Acts as a magnesium transporter K06213 - - 3.339e-202 638.0
HSJS2_k127_1714768_1 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 368.0
HSJS2_k127_1714768_2 PTS fructose transporter subunit IIA K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000099 221.0
HSJS2_k127_1714768_3 Phosphocarrier protein HPr K08485,K11189 - - 0.0000000000000000000000000006116 115.0
HSJS2_k127_1714768_4 Ubiquitinol-cytochrome C reductase Fe-S subunit TAT signal K00411 - 1.10.2.2 0.0000006943 58.0
HSJS2_k127_1724401_0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 613.0
HSJS2_k127_1724401_1 COG0642 Signal transduction histidine kinase K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 332.0
HSJS2_k127_1724401_2 D-Amino acid dehydrogenase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000001544 231.0
HSJS2_k127_1724401_3 Type II transport protein GspH K08084 - - 0.000007815 54.0
HSJS2_k127_1724985_0 efflux pump K18138 - - 0.0 1386.0
HSJS2_k127_1724985_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 2.384e-277 860.0
HSJS2_k127_1724985_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 292.0
HSJS2_k127_1724985_3 - - - - 0.000000000000000000000000000000000000000000000000000001871 194.0
HSJS2_k127_1724985_4 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000009332 171.0
HSJS2_k127_1724985_5 type III effector - - - 0.00000000000000000000000000000001427 130.0
HSJS2_k127_1724985_6 cold-shock protein K03704 - - 0.0000000000000000002454 87.0
HSJS2_k127_1724985_7 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.0000000004657 60.0
HSJS2_k127_172754_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 609.0
HSJS2_k127_172754_1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000008891 216.0
HSJS2_k127_172754_2 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000007266 136.0
HSJS2_k127_1729254_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 7.285e-205 644.0
HSJS2_k127_1729254_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 384.0
HSJS2_k127_1729254_2 Protein of unknown function (DUF938) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000184 250.0
HSJS2_k127_1729254_3 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide K02439 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016740,GO:0016782,GO:0016783,GO:0044424,GO:0044464 2.8.1.1 0.00000000000000000000001263 104.0
HSJS2_k127_1729808_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.099e-314 978.0
HSJS2_k127_1729808_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 546.0
HSJS2_k127_1729808_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000144 275.0
HSJS2_k127_1729808_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000005975 141.0
HSJS2_k127_1731166_0 GMC oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 441.0
HSJS2_k127_173199_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1053.0
HSJS2_k127_173199_1 Histidine kinase - - - 3.496e-277 877.0
HSJS2_k127_173199_10 cytochrome c5 - - - 0.0000000000000000000000000000000000000000000000000000000000000006896 222.0
HSJS2_k127_173199_11 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04752 - - 0.000000000000000000000000000000000000000000000000000000000000005766 216.0
HSJS2_k127_173199_12 COG2076 Membrane transporters of cations and cationic drugs K11741 - - 0.000000000000000000000000000000000000000005514 156.0
HSJS2_k127_173199_13 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000001447 136.0
HSJS2_k127_173199_14 START domain - - - 0.000000000000000000000000000001986 124.0
HSJS2_k127_173199_16 protein conserved in bacteria K09806 - - 0.000000000000000000000000001725 115.0
HSJS2_k127_173199_17 - - - - 0.000000000000000000000000009787 117.0
HSJS2_k127_173199_18 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000002468 124.0
HSJS2_k127_173199_19 Domain of unknown function (DUF4105) - - - 0.000000000000000000001456 97.0
HSJS2_k127_173199_2 Ammonium Transporter K03320 - - 1.079e-217 681.0
HSJS2_k127_173199_21 SPRY domain - - - 0.0000006545 63.0
HSJS2_k127_173199_3 ATPase with chaperone activity K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 540.0
HSJS2_k127_173199_4 Heat shock 70 kDa protein K04045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 526.0
HSJS2_k127_173199_5 consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 386.0
HSJS2_k127_173199_6 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 351.0
HSJS2_k127_173199_7 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 340.0
HSJS2_k127_173199_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 312.0
HSJS2_k127_1733318_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009485 579.0
HSJS2_k127_1733318_1 transporter component K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000008488 234.0
HSJS2_k127_1733318_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000002941 204.0
HSJS2_k127_1733318_3 transporter component K07112 - - 0.00000000000000000000000000000000000000000000000000007244 189.0
HSJS2_k127_1733318_4 helix_turn_helix, Arsenical Resistance Operon Repressor - GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000004559 136.0
HSJS2_k127_1734621_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 541.0
HSJS2_k127_1734621_1 - - - - 0.000000000001938 68.0
HSJS2_k127_1741413_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 7.23e-227 729.0
HSJS2_k127_1741413_1 belongs to the carbohydrate kinase PfkB family K00847,K00892 - 2.7.1.4,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 481.0
HSJS2_k127_1741413_2 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 334.0
HSJS2_k127_1741413_3 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000004174 214.0
HSJS2_k127_1741413_4 Rieske 2Fe-2S - - - 0.00000000000000000000000000000000000000000006754 163.0
HSJS2_k127_1741413_5 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000002962 123.0
HSJS2_k127_1741413_6 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000001773 126.0
HSJS2_k127_1743664_0 Protein of unknown function (DUF1298) K00635 - 2.3.1.20 3.524e-238 741.0
HSJS2_k127_1743664_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003904 342.0
HSJS2_k127_1743664_2 Histidine kinase K20972 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 323.0
HSJS2_k127_1743664_3 cold-shock protein K03704 - - 0.0000000000000000000000000000001795 123.0
HSJS2_k127_1761789_0 fatty acid hydroxylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 428.0
HSJS2_k127_1761789_1 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 324.0
HSJS2_k127_1761789_2 transcriptional regulator - - - 0.00000000000000000000000000000000000001194 147.0
HSJS2_k127_1764474_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 496.0
HSJS2_k127_1764474_1 Domain of unknown function (DUF4154) - - - 0.0000000000000000000000007722 111.0
HSJS2_k127_1775914_0 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 343.0
HSJS2_k127_1775914_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 338.0
HSJS2_k127_1775914_2 COG0625 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000371 265.0
HSJS2_k127_1775914_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000002045 175.0
HSJS2_k127_1775914_4 - - - - 0.00000000000000000000000006556 108.0
HSJS2_k127_1775914_5 - - - - 0.000000000000000000216 91.0
HSJS2_k127_1781984_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 4.566e-223 699.0
HSJS2_k127_1781984_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 467.0
HSJS2_k127_1781984_2 PFAM Prolipoprotein diacylglyceryl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008251 365.0
HSJS2_k127_1781984_3 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 310.0
HSJS2_k127_1781984_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006648 274.0
HSJS2_k127_1781984_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000473 140.0
HSJS2_k127_1781984_6 RDD family K18481 - - 0.000000000000002453 82.0
HSJS2_k127_1781984_7 LVIVD repeat - - - 0.000000000001548 70.0
HSJS2_k127_1781984_8 Transcriptional regulators - - - 0.000004603 51.0
HSJS2_k127_1792355_0 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007742 545.0
HSJS2_k127_1792355_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 357.0
HSJS2_k127_1792355_2 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001126 242.0
HSJS2_k127_1792355_3 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.00000000000000000000000000000000000000000000000000000000000002049 225.0
HSJS2_k127_1792355_4 Peptidase M22 K14742 - - 0.00000000000000000000000000000000000000000000001305 181.0
HSJS2_k127_1808273_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1247.0
HSJS2_k127_1808273_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 3.894e-210 658.0
HSJS2_k127_1808273_10 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000000004937 201.0
HSJS2_k127_1808273_11 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000000000000000000000000000000000000000000003517 170.0
HSJS2_k127_1808273_12 Ion channel - - - 0.0000000000000000000000000007499 118.0
HSJS2_k127_1808273_13 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.0000000000000000000000000007977 115.0
HSJS2_k127_1808273_14 Modulates RecA activity K03565 - - 0.00000000000000000000003264 109.0
HSJS2_k127_1808273_15 Bacterioferritin-associated ferredoxin K02192 - - 0.000000000000000000002944 94.0
HSJS2_k127_1808273_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 600.0
HSJS2_k127_1808273_3 COG0642 Signal transduction histidine kinase K07641 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 461.0
HSJS2_k127_1808273_4 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 459.0
HSJS2_k127_1808273_5 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 324.0
HSJS2_k127_1808273_6 Inner membrane protein CreD K06143 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 310.0
HSJS2_k127_1808273_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004922 261.0
HSJS2_k127_1808273_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004124 244.0
HSJS2_k127_1808273_9 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000001914 209.0
HSJS2_k127_1821312_0 HsdM N-terminal domain K03427 - 2.1.1.72 0.0 1354.0
HSJS2_k127_1821312_1 HsdM N-terminal domain K03427 - 2.1.1.72 0.00000000000000000000000000000000000000000000009055 170.0
HSJS2_k127_1821312_2 restriction modification system DNA specificity K01154 - 3.1.21.3 0.000000000000000000000001158 106.0
HSJS2_k127_1833702_0 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 1.476e-198 640.0
HSJS2_k127_1833702_1 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000002664 212.0
HSJS2_k127_1833702_2 consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000005094 155.0
HSJS2_k127_1833702_3 Methyltransferase, chemotaxis proteins - - - 0.000000000000000000000000000000000000005515 161.0
HSJS2_k127_1833702_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000001401 91.0
HSJS2_k127_1833702_5 Pfam CheW-like K03408 - - 0.0000000003212 72.0
HSJS2_k127_1833702_6 - - - - 0.00000007449 60.0
HSJS2_k127_1833870_0 Sulfite reductase K00381 - 1.8.1.2 2.315e-283 878.0
HSJS2_k127_1833870_1 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 348.0
HSJS2_k127_1833870_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000002656 228.0
HSJS2_k127_1833870_3 Protein of unknown function (DUF2970) - - - 0.000000000000001214 84.0
HSJS2_k127_1843839_0 Lipoprotein releasing system, transmembrane protein K09808 - - 9.92e-204 640.0
HSJS2_k127_1843839_1 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 388.0
HSJS2_k127_1843839_2 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009518 288.0
HSJS2_k127_1843839_3 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000000000000000000002184 233.0
HSJS2_k127_1843839_4 - - - - 0.000000000000000000000001077 116.0
HSJS2_k127_186219_0 Isocitrate lyase K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 376.0
HSJS2_k127_186219_1 belongs to the bacterial solute-binding protein 3 family K02030,K02424,K10036 - - 0.000000000000000000000000000000000000000000000000000000000000000000011 243.0
HSJS2_k127_1871448_0 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 548.0
HSJS2_k127_1871448_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 504.0
HSJS2_k127_1871448_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 406.0
HSJS2_k127_1871448_3 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 286.0
HSJS2_k127_1871448_4 Protein of unknown function (DUF2846) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 283.0
HSJS2_k127_1871448_5 Protein of unknown function (DUF1289) K06938 - - 0.000000000000000000000000000000000000000000000000000000003161 205.0
HSJS2_k127_1871448_6 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000008297 204.0
HSJS2_k127_1871448_7 Cupin - - - 0.00000000000000000000000000000000002534 139.0
HSJS2_k127_1871448_8 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.00000000000000000000000000000000163 135.0
HSJS2_k127_1871448_9 OmpA family - - - 0.0000000000001909 70.0
HSJS2_k127_1884633_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 2.11e-228 719.0
HSJS2_k127_1884633_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003009 285.0
HSJS2_k127_1884633_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000001739 226.0
HSJS2_k127_1884633_3 - - - - 0.000000000000000000000000000000000000000000003292 172.0
HSJS2_k127_1884633_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000228 66.0
HSJS2_k127_1884633_7 - - - - 0.0000006677 52.0
HSJS2_k127_1884633_9 - - - - 0.0002035 46.0
HSJS2_k127_1892724_0 Alpha-2-Macroglobulin K06894 - - 0.0 1439.0
HSJS2_k127_1892724_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 8.27e-222 714.0
HSJS2_k127_1892724_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 587.0
HSJS2_k127_1892724_3 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 435.0
HSJS2_k127_1892724_4 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 426.0
HSJS2_k127_1892724_5 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000006913 231.0
HSJS2_k127_1892724_6 An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH K00240,K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 1.3.5.1,1.3.5.4 0.000000000000000000003607 95.0
HSJS2_k127_1892724_7 COG1012 NAD-dependent aldehyde dehydrogenases K00140 - 1.2.1.18,1.2.1.27 0.000000000000000003267 84.0
HSJS2_k127_1892724_8 membrane protein (homolog of Drosophila rhomboid) - - - 0.000000009582 61.0
HSJS2_k127_1897372_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.181e-275 861.0
HSJS2_k127_1897372_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 560.0
HSJS2_k127_1897372_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 327.0
HSJS2_k127_1897372_3 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000000000172 251.0
HSJS2_k127_1897372_4 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000008268 170.0
HSJS2_k127_1900045_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 474.0
HSJS2_k127_1900045_1 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 340.0
HSJS2_k127_1900045_2 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000004063 145.0
HSJS2_k127_1900045_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000002868 132.0
HSJS2_k127_1900903_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1272.0
HSJS2_k127_1900903_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.604e-241 748.0
HSJS2_k127_1900903_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 453.0
HSJS2_k127_1900903_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 473.0
HSJS2_k127_1900903_4 Belongs to the ABC transporter superfamily K13896 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006857,GO:0008144,GO:0008150,GO:0015399,GO:0015405,GO:0015833,GO:0015893,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0035672,GO:0036094,GO:0042221,GO:0042493,GO:0042623,GO:0042626,GO:0042884,GO:0042886,GO:0042891,GO:0043167,GO:0043168,GO:0043492,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 413.0
HSJS2_k127_1900903_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 391.0
HSJS2_k127_1900903_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000000634 155.0
HSJS2_k127_1900903_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000001778 154.0
HSJS2_k127_1916294_0 aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 515.0
HSJS2_k127_1916294_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 413.0
HSJS2_k127_1916294_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 296.0
HSJS2_k127_1916294_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000005416 224.0
HSJS2_k127_1916294_4 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000009446 224.0
HSJS2_k127_1916294_5 START domain - - - 0.00000000000000000000000000000000000000005134 160.0
HSJS2_k127_1921871_0 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - - 2.124e-279 875.0
HSJS2_k127_1921871_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 2.433e-260 814.0
HSJS2_k127_1921871_10 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000005648 120.0
HSJS2_k127_1921871_2 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 439.0
HSJS2_k127_1921871_3 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 415.0
HSJS2_k127_1921871_4 Major facilitator superfamily K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000938 346.0
HSJS2_k127_1921871_5 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000001883 233.0
HSJS2_k127_1921871_6 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000003421 193.0
HSJS2_k127_1921871_7 - - - - 0.000000000000000000000000000000000000000000000007812 175.0
HSJS2_k127_1921871_8 Transcriptional - - - 0.00000000000000000000000000000000000000000005093 166.0
HSJS2_k127_1921871_9 - - - - 0.0000000000000000000000000000000001643 135.0
HSJS2_k127_1923052_0 twitching motility protein K02670 - - 8.554e-215 670.0
HSJS2_k127_1923052_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006123 243.0
HSJS2_k127_192989_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 5.426e-204 650.0
HSJS2_k127_192989_1 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 298.0
HSJS2_k127_192989_2 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000001953 163.0
HSJS2_k127_1958256_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 528.0
HSJS2_k127_1958256_1 Dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 325.0
HSJS2_k127_1958785_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.02e-312 961.0
HSJS2_k127_1958785_1 Belongs to the aldehyde dehydrogenase family K00128,K06447 - 1.2.1.3,1.2.1.71 1.839e-265 822.0
HSJS2_k127_1958785_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 433.0
HSJS2_k127_1958785_3 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 0.000000000000000003509 87.0
HSJS2_k127_1972840_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 449.0
HSJS2_k127_1972840_1 Bacterial low temperature requirement A protein (LtrA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008404 415.0
HSJS2_k127_1972840_2 NAD(P)H-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000001215 224.0
HSJS2_k127_1972840_3 COG0235 Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases - - - 0.00000000000000000000000000000000000000000000000000000000001452 209.0
HSJS2_k127_1972840_4 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000005071 158.0
HSJS2_k127_1972840_5 Protein of unknown function (DUF805) - - - 0.00000000000000000000000000000000001031 142.0
HSJS2_k127_1972840_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000004491 106.0
HSJS2_k127_197946_0 COG2303 Choline dehydrogenase and related flavoproteins K03333 - 1.1.3.6 6.445e-248 775.0
HSJS2_k127_197946_1 Membrane - - - 0.00000000000000000000000000000000000000000000000004106 186.0
HSJS2_k127_197946_2 Protein of unknown function (DUF2914) - - - 0.000000000000000001014 97.0
HSJS2_k127_2002659_1 Ankyrin TPR repeat protein - - - 0.00001482 56.0
HSJS2_k127_201285_0 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 288.0
HSJS2_k127_201285_1 Methyl-transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004541 258.0
HSJS2_k127_201285_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000006694 188.0
HSJS2_k127_201285_3 FecR protein - - - 0.000000000000000000002687 108.0
HSJS2_k127_2022847_0 protein conserved in bacteria K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 434.0
HSJS2_k127_2022847_1 TatD family K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 357.0
HSJS2_k127_2022847_2 protein conserved in bacteria K09760 - - 0.00006325 49.0
HSJS2_k127_202480_0 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 - 6.1.1.4 1.337e-305 944.0
HSJS2_k127_202480_1 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 422.0
HSJS2_k127_202480_2 DNA polymerase III K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 387.0
HSJS2_k127_202480_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000004509 114.0
HSJS2_k127_2039008_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 3.048e-265 823.0
HSJS2_k127_2039008_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 387.0
HSJS2_k127_2039008_2 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 316.0
HSJS2_k127_2039008_3 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000006067 236.0
HSJS2_k127_2039008_4 - - - - 0.00000000000000000000000000000000000008499 148.0
HSJS2_k127_2057069_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 416.0
HSJS2_k127_2057069_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 331.0
HSJS2_k127_2072292_0 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147,K18893 - - 8.803e-266 830.0
HSJS2_k127_2072292_1 COG3243 Poly(3-hydroxyalkanoate) synthetase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 485.0
HSJS2_k127_2072292_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001284 267.0
HSJS2_k127_2072292_3 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003515 264.0
HSJS2_k127_2072292_4 COG0655 Multimeric flavodoxin WrbA - - - 0.0000000000000000000000000000000000000000000000000000000000000001975 226.0
HSJS2_k127_2072292_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000179 68.0
HSJS2_k127_2073857_0 redox protein, regulator of disulfide bond formation K09136 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0047429,GO:0047693,GO:0071704,GO:1901564 - 0.0 1331.0
HSJS2_k127_2073857_1 Belongs to the amidase family K01426 - 3.5.1.4 8.225e-213 667.0
HSJS2_k127_2073857_2 MarR family - - - 0.000000000000000000000000000000000004884 143.0
HSJS2_k127_2073857_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000002208 136.0
HSJS2_k127_2073857_4 S4 domain K14761 - - 0.00000000000000008761 80.0
HSJS2_k127_2080007_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 580.0
HSJS2_k127_2080007_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 521.0
HSJS2_k127_2080007_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 355.0
HSJS2_k127_2090432_0 COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 614.0
HSJS2_k127_2090432_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 507.0
HSJS2_k127_2090432_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004697 429.0
HSJS2_k127_2090432_3 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000004142 218.0
HSJS2_k127_2090432_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000001505 198.0
HSJS2_k127_2090432_5 COG4966 Tfp pilus assembly protein PilW K02672 - - 0.000000000000000000000000000000000000000000000005629 182.0
HSJS2_k127_2090432_6 protein transport across the cell outer membrane K08084 - - 0.000000000000000000000000000000006963 133.0
HSJS2_k127_2090432_7 Tfp pilus assembly protein PilE K02655 - - 0.0000000000000000000000000000109 123.0
HSJS2_k127_2090432_8 Prokaryotic N-terminal methylation motif K02671 - - 0.0000000000000000000000000002461 121.0
HSJS2_k127_2090432_9 Pilus assembly protein PilX - - - 0.00000000000000000000000006148 114.0
HSJS2_k127_2094672_0 of the RND superfamily K07003 - - 0.0 1138.0
HSJS2_k127_2094672_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 493.0
HSJS2_k127_2094672_2 protein related to plant photosystem II stability - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 360.0
HSJS2_k127_2094672_3 COG1073 Hydrolases of the alpha beta superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 304.0
HSJS2_k127_2094672_4 During stationary phase, converts 70S ribosomes to an inactive dimeric form (100S ribosomes) K03812 - - 0.00000000000000000000001444 101.0
HSJS2_k127_2094672_5 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000385 102.0
HSJS2_k127_209945_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.353e-215 672.0
HSJS2_k127_209945_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 477.0
HSJS2_k127_209945_2 LuxR family transcriptional regulator K04333,K20918 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 315.0
HSJS2_k127_209945_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000799 252.0
HSJS2_k127_209945_4 Type II secretion system protein C K02452 - - 0.00000000000000000000000000000000000000000000000000000000000003202 224.0
HSJS2_k127_209945_5 Type II secretion system (T2SS), protein N K02463 - - 0.00000000000000000000000000000000001073 144.0
HSJS2_k127_211073_0 oxidoreductase K07222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 552.0
HSJS2_k127_2116279_0 Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate K00265 - 1.4.1.13,1.4.1.14 0.0 1440.0
HSJS2_k127_2116279_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 8.375e-284 875.0
HSJS2_k127_2116279_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 2.764e-199 624.0
HSJS2_k127_2116279_3 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000004676 137.0
HSJS2_k127_2129745_0 esterase of the alpha-beta hydrolase superfamily K07001 - - 1.428e-235 737.0
HSJS2_k127_2129745_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 548.0
HSJS2_k127_2129745_10 protein conserved in bacteria K09938 - - 0.00001622 51.0
HSJS2_k127_2129745_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 438.0
HSJS2_k127_2129745_3 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 377.0
HSJS2_k127_2129745_4 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005077 359.0
HSJS2_k127_2129745_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 297.0
HSJS2_k127_2129745_6 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001802 260.0
HSJS2_k127_2129745_7 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000006955 214.0
HSJS2_k127_2129745_8 Periplasmic sensor domain found in signal transduction proteins - - - 0.0000000000000000000000000000000000000000000004076 175.0
HSJS2_k127_2129745_9 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000001716 147.0
HSJS2_k127_2162455_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 8.298e-232 727.0
HSJS2_k127_2162455_1 PFAM Tex-like protein N-terminal K06959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 600.0
HSJS2_k127_217269_0 AraC family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 467.0
HSJS2_k127_217269_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003544 271.0
HSJS2_k127_217269_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000001044 222.0
HSJS2_k127_217269_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000000000000000000000000008663 192.0
HSJS2_k127_217269_4 - - - - 0.000000000000000000004341 95.0
HSJS2_k127_217269_5 Cysteine-rich CPXCG - - - 0.00000000000005198 73.0
HSJS2_k127_2180378_0 secretion pathway protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 348.0
HSJS2_k127_2180378_1 Forkhead associated domain - - - 0.00000000000000000000000000000000000000008864 162.0
HSJS2_k127_2181382_0 DinB superfamily - - - 3.886e-196 621.0
HSJS2_k127_2181382_1 Beta-lactamase class C and other penicillin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 484.0
HSJS2_k127_2181382_2 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 411.0
HSJS2_k127_2181382_3 membrane - - - 0.0000000000000000000000000000000000000000002917 160.0
HSJS2_k127_2181382_4 mRNA catabolic process - - - 0.000000000000000000000002957 103.0
HSJS2_k127_2188899_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 5.358e-290 924.0
HSJS2_k127_2188899_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K11085 - - 1.258e-224 710.0
HSJS2_k127_2188899_10 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000000000000000000001382 184.0
HSJS2_k127_2188899_11 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000001383 156.0
HSJS2_k127_2188899_2 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 430.0
HSJS2_k127_2188899_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 367.0
HSJS2_k127_2188899_4 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 354.0
HSJS2_k127_2188899_5 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 361.0
HSJS2_k127_2188899_6 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 322.0
HSJS2_k127_2188899_7 MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 286.0
HSJS2_k127_2188899_8 hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000001359 196.0
HSJS2_k127_2188899_9 protein conserved in bacteria K09928 - - 0.00000000000000000000000000000000000000000000000000000246 195.0
HSJS2_k127_2199802_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 374.0
HSJS2_k127_2199802_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000002335 189.0
HSJS2_k127_2205562_0 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 560.0
HSJS2_k127_2205562_1 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 404.0
HSJS2_k127_2205562_2 Domain of Unknown Function (DUF349) - - - 0.00000000000000000000000000000000000000000000000000000000004801 224.0
HSJS2_k127_2205562_3 - - - - 0.000000000000000000000000000000001314 142.0
HSJS2_k127_2205562_4 Bacterial SH3 domain K07184 - - 0.00003723 46.0
HSJS2_k127_2210057_0 argininosuccinate lyase K01755 - 4.3.2.1 4.566e-262 811.0
HSJS2_k127_2210057_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 9.938e-219 685.0
HSJS2_k127_2210057_2 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 431.0
HSJS2_k127_2210057_3 Response regulator of the LytR AlgR family K02477,K08083 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 359.0
HSJS2_k127_2210057_4 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009967 254.0
HSJS2_k127_2210057_5 TRL-like protein family - - - 0.000000000000000000000000000000000000000002888 156.0
HSJS2_k127_2210057_6 - - - - 0.0000002356 53.0
HSJS2_k127_2219761_0 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 467.0
HSJS2_k127_2219761_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006363 342.0
HSJS2_k127_2219761_2 Domain of unknown function (DUF4331) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001711 263.0
HSJS2_k127_2219761_3 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000001952 164.0
HSJS2_k127_2227961_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.492e-245 760.0
HSJS2_k127_2227961_1 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 519.0
HSJS2_k127_2227961_2 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 382.0
HSJS2_k127_2227961_3 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 340.0
HSJS2_k127_2227961_4 PepSY-associated TM region - - - 0.00000000000000000000000000000000000000000000000000000001503 205.0
HSJS2_k127_2227961_5 FMN_bind - - - 0.0000000000000000000000000000000000000000000000002354 183.0
HSJS2_k127_2227961_6 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000009922 68.0
HSJS2_k127_2230068_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 3.296e-222 693.0
HSJS2_k127_2230068_1 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 2.387e-201 654.0
HSJS2_k127_2230068_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K22478 - 2.3.1.1,2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 483.0
HSJS2_k127_2230068_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 389.0
HSJS2_k127_2230068_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 333.0
HSJS2_k127_2230068_5 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006734 259.0
HSJS2_k127_2230068_6 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000001293 253.0
HSJS2_k127_2230068_7 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000001091 153.0
HSJS2_k127_2230068_8 Pfam Transposase IS66 - - - 0.00000000000000000000000000002262 125.0
HSJS2_k127_2230068_9 stress-induced protein - - - 0.00000000000000000000672 94.0
HSJS2_k127_2242808_0 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 351.0
HSJS2_k127_2251849_0 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 420.0
HSJS2_k127_2251849_1 O-Antigen Polymerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008868 364.0
HSJS2_k127_2251849_2 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 330.0
HSJS2_k127_2251849_3 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009065 255.0
HSJS2_k127_2251849_4 glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000006018 199.0
HSJS2_k127_2251849_5 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000857 148.0
HSJS2_k127_2251849_6 - - - - 0.00000000000000000000000000000008653 141.0
HSJS2_k127_2251849_7 Pkd domain containing protein - - - 0.0000000000000000000000000000002575 136.0
HSJS2_k127_2251849_8 DUF218 domain - - - 0.000000000000000000000000006701 119.0
HSJS2_k127_2254086_0 COG1960 Acyl-CoA dehydrogenases - - - 1.598e-247 767.0
HSJS2_k127_2254086_1 7TMR-DISM extracellular 2 - - - 7.348e-225 711.0
HSJS2_k127_2256508_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 5.891e-254 790.0
HSJS2_k127_2256508_1 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 571.0
HSJS2_k127_2256508_2 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 341.0
HSJS2_k127_2256508_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002553 268.0
HSJS2_k127_2261732_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1172.0
HSJS2_k127_2261732_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 5.948e-274 861.0
HSJS2_k127_2261732_10 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001526 263.0
HSJS2_k127_2261732_11 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019222,GO:0019439,GO:0034353,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000003266 216.0
HSJS2_k127_2261732_12 Iron-regulated protein - - - 0.00000000000000000000002644 113.0
HSJS2_k127_2261732_2 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 537.0
HSJS2_k127_2261732_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 428.0
HSJS2_k127_2261732_4 pseudouridine methyltransferase K16317 - 2.1.1.257 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 306.0
HSJS2_k127_2261732_5 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 302.0
HSJS2_k127_2261732_6 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 295.0
HSJS2_k127_2261732_7 phosphoserine phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007813 293.0
HSJS2_k127_2261732_8 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 282.0
HSJS2_k127_2261732_9 including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
HSJS2_k127_2266679_0 - - - - 0.0 1058.0
HSJS2_k127_2266679_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 645.0
HSJS2_k127_2266679_2 COG1073 Hydrolases of the alpha beta superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 309.0
HSJS2_k127_2266679_3 TM2 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000001558 194.0
HSJS2_k127_2266679_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000002438 155.0
HSJS2_k127_2266679_5 YecR-like lipoprotein - - - 0.0000000000000000000000000000000009045 132.0
HSJS2_k127_2266679_6 fatty acid desaturase K00508 - 1.14.19.3 0.000000000003702 66.0
HSJS2_k127_2266679_7 - - - - 0.00000000005706 64.0
HSJS2_k127_2274996_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 437.0
HSJS2_k127_2274996_1 Neuraminidase (sialidase) - - - 0.000000000000000000000000000000000000000000000000000000000000000008583 230.0
HSJS2_k127_2280403_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.776e-243 755.0
HSJS2_k127_2280403_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.506e-224 702.0
HSJS2_k127_2280403_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 521.0
HSJS2_k127_2280403_3 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 404.0
HSJS2_k127_2280403_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 385.0
HSJS2_k127_2280403_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 337.0
HSJS2_k127_2280403_6 HflC and HflK could regulate a protease K04087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 323.0
HSJS2_k127_2280403_7 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000002925 142.0
HSJS2_k127_2280403_8 - - - - 0.000000000000000000000001573 107.0
HSJS2_k127_2280403_9 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.00000003393 57.0
HSJS2_k127_2287576_0 Glutathione S-transferase K07393 - 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006063 474.0
HSJS2_k127_2287576_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 366.0
HSJS2_k127_2287576_2 Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity K01118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008907 247.0
HSJS2_k127_2287576_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009824 244.0
HSJS2_k127_2287576_4 COG5008 Tfp pilus assembly protein, ATPase PilU K02670 - - 0.00006241 52.0
HSJS2_k127_2287576_5 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008144,GO:0008150,GO:0008509,GO:0015075,GO:0015098,GO:0015103,GO:0015318,GO:0015399,GO:0015405,GO:0015412,GO:0015689,GO:0015698,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043225,GO:0043492,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0097159,GO:0097367,GO:0098656,GO:0099133,GO:1901265,GO:1901363 3.6.3.29 0.0001754 45.0
HSJS2_k127_2297495_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003967 280.0
HSJS2_k127_2297495_2 tonB-system energizer ExbB K03561 - - 0.0000000000000000005891 92.0
HSJS2_k127_2303047_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5e-324 998.0
HSJS2_k127_2303047_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 574.0
HSJS2_k127_2303047_11 Bacterial DNA-binding protein - - - 0.000000000000000000000000000000000000008018 150.0
HSJS2_k127_2303047_12 - - - - 0.0000000006119 60.0
HSJS2_k127_2303047_2 Transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 376.0
HSJS2_k127_2303047_3 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 329.0
HSJS2_k127_2303047_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007564 271.0
HSJS2_k127_2303047_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000000000000003745 236.0
HSJS2_k127_2303047_6 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000002579 205.0
HSJS2_k127_2303047_7 Biopolymer transport protein K03560 - - 0.0000000000000000000000000000000000000000000000000000001863 199.0
HSJS2_k127_2303047_8 Thioesterase K01075,K07107 - 3.1.2.23 0.0000000000000000000000000000000000000000000000003091 181.0
HSJS2_k127_2303047_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000615 178.0
HSJS2_k127_231084_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1386.0
HSJS2_k127_231084_1 acetolactate synthase K01652 - 2.2.1.6 0.0 1008.0
HSJS2_k127_231084_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 9.178e-199 621.0
HSJS2_k127_231084_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 370.0
HSJS2_k127_231084_4 acetolactate synthase K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 284.0
HSJS2_k127_231084_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001842 252.0
HSJS2_k127_231084_6 Domain of unknown function (DUF4124) - - - 0.0000000000000000004615 96.0
HSJS2_k127_2315100_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 311.0
HSJS2_k127_2315100_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 304.0
HSJS2_k127_2323004_0 Belongs to the GMC oxidoreductase family - - - 3.818e-261 812.0
HSJS2_k127_2323004_1 Pkd domain containing protein - - - 5.347e-219 692.0
HSJS2_k127_2323004_2 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 4.411e-207 653.0
HSJS2_k127_2323004_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000005899 173.0
HSJS2_k127_2325830_0 Long-chain fatty acid transport protein - - - 2.565e-289 896.0
HSJS2_k127_2325830_1 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 471.0
HSJS2_k127_2325830_2 double-glycine peptidase K06992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 409.0
HSJS2_k127_2325830_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 383.0
HSJS2_k127_2325830_4 COG0147 Anthranilate para-aminobenzoate synthases component I K01665 - 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 369.0
HSJS2_k127_2325830_5 - - - - 0.00000000000000000000000000000000000000000000002683 182.0
HSJS2_k127_2330145_0 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 392.0
HSJS2_k127_2330145_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.0000000000000000000000000000000000000000000001081 173.0
HSJS2_k127_2330145_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000000000000007715 146.0
HSJS2_k127_2334602_0 unusual protein kinase - - - 1.133e-232 726.0
HSJS2_k127_2334602_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 608.0
HSJS2_k127_2334602_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008571 518.0
HSJS2_k127_2334602_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000004414 211.0
HSJS2_k127_2334602_4 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.00000000000000000000000000000000000001202 148.0
HSJS2_k127_2346463_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1222.0
HSJS2_k127_2346463_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1152.0
HSJS2_k127_2346463_10 heptosyltransferase K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 482.0
HSJS2_k127_2346463_11 COG0859 ADP-heptose LPS heptosyltransferase K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 464.0
HSJS2_k127_2346463_12 Catalyzes the addition of the first glucose residue to the LPS core K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 452.0
HSJS2_k127_2346463_13 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008361 444.0
HSJS2_k127_2346463_14 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 431.0
HSJS2_k127_2346463_15 COG0330 Membrane protease subunits stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006635 414.0
HSJS2_k127_2346463_16 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 390.0
HSJS2_k127_2346463_17 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 383.0
HSJS2_k127_2346463_18 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 365.0
HSJS2_k127_2346463_19 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 365.0
HSJS2_k127_2346463_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1127.0
HSJS2_k127_2346463_20 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
HSJS2_k127_2346463_21 Glycosyltransferase like family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 327.0
HSJS2_k127_2346463_22 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 316.0
HSJS2_k127_2346463_23 esterase K07000 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 286.0
HSJS2_k127_2346463_24 Outer membrane efflux protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 296.0
HSJS2_k127_2346463_25 protein conserved in bacteria K09920 - - 0.0000000000000000000000000000000000000000000006162 170.0
HSJS2_k127_2346463_26 of membrane protease K07340 - - 0.0000000000000000000000000000000001726 137.0
HSJS2_k127_2346463_27 - - - - 0.00000000000000000000351 108.0
HSJS2_k127_2346463_3 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1098.0
HSJS2_k127_2346463_4 type II secretion system protein K02454 - - 9.13e-301 932.0
HSJS2_k127_2346463_5 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 1.678e-228 716.0
HSJS2_k127_2346463_6 phosphate transporter K03306 - - 9.718e-202 634.0
HSJS2_k127_2346463_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 523.0
HSJS2_k127_2346463_8 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 498.0
HSJS2_k127_2346463_9 COG0578 Glycerol-3-phosphate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 493.0
HSJS2_k127_2358420_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 1.005e-211 666.0
HSJS2_k127_2358420_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 3.105e-195 621.0
HSJS2_k127_2358420_10 hydrolase K10806 - - 0.000000000000000000000000000000000000000000000000000000001253 203.0
HSJS2_k127_2358420_11 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000004243 184.0
HSJS2_k127_2358420_12 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000001415 168.0
HSJS2_k127_2358420_13 Transcriptional K03892 - - 0.00000000000000000000000000000003541 128.0
HSJS2_k127_2358420_14 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000134 84.0
HSJS2_k127_2358420_15 Belongs to the SlyX family K03745 - - 0.000000000002947 69.0
HSJS2_k127_2358420_2 Phosphate ABC transporter substrate-binding protein K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 548.0
HSJS2_k127_2358420_3 Domain of unknown function (DUF3333) K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 543.0
HSJS2_k127_2358420_4 SBF-like CPA transporter family (DUF4137) K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 494.0
HSJS2_k127_2358420_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 479.0
HSJS2_k127_2358420_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 402.0
HSJS2_k127_2358420_7 NADPH-dependent FMN reductase K11811 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002309 382.0
HSJS2_k127_2358420_8 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 304.0
HSJS2_k127_2358420_9 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002116 249.0
HSJS2_k127_2373408_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 554.0
HSJS2_k127_2373408_1 COG0720 6-pyruvoyl-tetrahydropterin synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001716 260.0
HSJS2_k127_2373408_2 Histidine kinase K10916 - 2.7.13.3 0.000000000000000000000002587 106.0
HSJS2_k127_2373408_3 Arc-like DNA binding domain - - - 0.00000000000008035 75.0
HSJS2_k127_238170_0 secretion pathway protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 597.0
HSJS2_k127_238170_1 Type II secretion system protein C K02452 - - 0.0000000000002927 70.0
HSJS2_k127_2384207_0 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 0.0 1028.0
HSJS2_k127_2384207_1 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.000009607 47.0
HSJS2_k127_2389229_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 502.0
HSJS2_k127_2389229_1 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 355.0
HSJS2_k127_2389229_2 COG1120 ABC-type cobalamin Fe3 -siderophores transport systems, ATPase components K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 289.0
HSJS2_k127_2396745_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1353.0
HSJS2_k127_2396745_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 1.214e-196 624.0
HSJS2_k127_2396745_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 560.0
HSJS2_k127_2396745_3 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 556.0
HSJS2_k127_2396745_4 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 413.0
HSJS2_k127_2396745_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 304.0
HSJS2_k127_2396745_6 haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 285.0
HSJS2_k127_2396745_7 reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002001 262.0
HSJS2_k127_2412295_0 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 2.638e-230 722.0
HSJS2_k127_2412295_1 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 527.0
HSJS2_k127_2412295_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 - 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 471.0
HSJS2_k127_2412295_3 overlaps another CDS with the same product name K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 334.0
HSJS2_k127_2412295_4 overlaps another CDS with the same product name K21019 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 327.0
HSJS2_k127_2412295_5 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000009168 182.0
HSJS2_k127_2412295_6 phosphate-selective porin O and P - - - 0.0000000000000000000000000003997 115.0
HSJS2_k127_2442190_0 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000000000000000000000000000000000000000000000000000001188 228.0
HSJS2_k127_2442190_1 Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1 1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division K13053,K14160 - - 0.0000000000000000000000000000000000000000000000001675 188.0
HSJS2_k127_2442190_2 Diguanylate cyclase - - - 0.000000000000000002261 89.0
HSJS2_k127_2442284_0 Catalyzes the reversible epimerization at C-2 of UDP-N- acetylglucosamine (UDP-GlcNAc) and thereby provides bacteria with UDP-N-acetylmannosamine (UDP-ManNAc), the activated donor of ManNAc residues K01791,K08068 - 3.2.1.183,5.1.3.14 2.912e-197 617.0
HSJS2_k127_2442284_1 Glycosyl transferase family 4 K13007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 470.0
HSJS2_k127_2442284_2 Male sterility protein K00091,K01784 - 1.1.1.219,5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000723 384.0
HSJS2_k127_2442284_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005549 250.0
HSJS2_k127_2446869_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.762e-264 825.0
HSJS2_k127_2446869_1 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 1.882e-257 809.0
HSJS2_k127_2446869_10 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271,K12961 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 315.0
HSJS2_k127_2446869_11 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 316.0
HSJS2_k127_2446869_12 hydrolase of the alpha beta superfamily K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 285.0
HSJS2_k127_2446869_13 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007748 281.0
HSJS2_k127_2446869_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 252.0
HSJS2_k127_2446869_15 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002957 250.0
HSJS2_k127_2446869_16 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000000000008936 213.0
HSJS2_k127_2446869_17 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000246 210.0
HSJS2_k127_2446869_18 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000003294 175.0
HSJS2_k127_2446869_19 protein conserved in bacteria K09908 - - 0.000000000000000000000000000000000000000000004101 169.0
HSJS2_k127_2446869_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.671e-246 765.0
HSJS2_k127_2446869_20 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000002846 140.0
HSJS2_k127_2446869_21 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000007741 101.0
HSJS2_k127_2446869_22 - - - - 0.000000000000002817 80.0
HSJS2_k127_2446869_3 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 532.0
HSJS2_k127_2446869_4 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 525.0
HSJS2_k127_2446869_5 (Lipo)protein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 520.0
HSJS2_k127_2446869_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 441.0
HSJS2_k127_2446869_7 Stringent starvation protein A K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 354.0
HSJS2_k127_2446869_8 Cytochrome c1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 325.0
HSJS2_k127_2446869_9 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005056 329.0
HSJS2_k127_2448710_0 Domain of unknown function (DUF3362) - - - 0.0 1209.0
HSJS2_k127_2448710_1 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000001443 216.0
HSJS2_k127_2448710_2 - - - - 0.00000000000000001173 88.0
HSJS2_k127_2458154_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 559.0
HSJS2_k127_2458154_1 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000005771 149.0
HSJS2_k127_2458154_3 protein conserved in bacteria - - - 0.000000000000000000006158 98.0
HSJS2_k127_2461130_0 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 460.0
HSJS2_k127_2461130_1 protein involved in outer membrane biogenesis K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 454.0
HSJS2_k127_2461130_2 a g-specific adenine glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 446.0
HSJS2_k127_2461130_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000001413 145.0
HSJS2_k127_2461130_4 - - - - 0.000000101 54.0
HSJS2_k127_2462695_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000595 529.0
HSJS2_k127_2462695_1 peptidase, M13 K01415,K07386 - 3.4.24.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 437.0
HSJS2_k127_2462695_2 CAAX amino terminal protease family K07052 - - 0.00000000004526 63.0
HSJS2_k127_2473102_0 Chemotaxis protein histidine kinase and related K02487,K06596 - - 0.0 2392.0
HSJS2_k127_2473102_1 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 494.0
HSJS2_k127_2473102_2 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K06597 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 434.0
HSJS2_k127_2473102_3 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575,K02661 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 417.0
HSJS2_k127_2473102_4 chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 329.0
HSJS2_k127_2473102_5 CheW-like domain K06598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000152 255.0
HSJS2_k127_2473102_6 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000003662 228.0
HSJS2_k127_2473405_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.938e-222 695.0
HSJS2_k127_2473405_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 2.414e-207 651.0
HSJS2_k127_2473405_10 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000007997 121.0
HSJS2_k127_2473405_11 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000000000000000000000000003264 117.0
HSJS2_k127_2473405_12 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000004724 114.0
HSJS2_k127_2473405_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007266 521.0
HSJS2_k127_2473405_3 Belongs to the peptidase S1C family K04691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 507.0
HSJS2_k127_2473405_4 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 474.0
HSJS2_k127_2473405_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0042802,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 422.0
HSJS2_k127_2473405_6 ABC transporter ATP-binding protein K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 405.0
HSJS2_k127_2473405_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 343.0
HSJS2_k127_2473405_8 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000001257 228.0
HSJS2_k127_2473405_9 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000000000000009432 223.0
HSJS2_k127_2478348_0 Histidine kinase K07639 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 417.0
HSJS2_k127_2478948_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 437.0
HSJS2_k127_2478948_1 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 428.0
HSJS2_k127_2478948_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 385.0
HSJS2_k127_2478948_3 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 301.0
HSJS2_k127_2478948_4 membrane - - - 0.0000000000000000000000000000000000000000000000000001179 188.0
HSJS2_k127_2478948_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000007446 179.0
HSJS2_k127_2478948_6 membrane - - - 0.00000000000000000000000000000000000000000000001883 175.0
HSJS2_k127_2478948_7 COG2104 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.0000000000000000000009614 98.0
HSJS2_k127_2478973_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1332.0
HSJS2_k127_2478973_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000004782 211.0
HSJS2_k127_2478973_2 ATPase, AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000003605 195.0
HSJS2_k127_2478973_3 Sugar-binding cellulase-like - - - 0.00000000000000000000000000000000000000000000119 173.0
HSJS2_k127_2480106_0 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 316.0
HSJS2_k127_2480106_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106026,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000005829 121.0
HSJS2_k127_2480106_2 - - - - 0.0000000000000000000004678 102.0
HSJS2_k127_2480916_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 1.506e-212 663.0
HSJS2_k127_2480916_1 COG1718 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000062 443.0
HSJS2_k127_2480916_2 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005048 247.0
HSJS2_k127_2480916_3 MAPEG family - - - 0.000000000000000000000000000000000000000000000000000000000000000017 226.0
HSJS2_k127_2480916_4 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000003299 79.0
HSJS2_k127_2482709_0 Domain of unknown function (DUF3391) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 341.0
HSJS2_k127_2482709_1 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000009036 125.0
HSJS2_k127_2486790_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 375.0
HSJS2_k127_2486790_1 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000005234 238.0
HSJS2_k127_2486790_2 protein SCO1 SenC PrrC, involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000008537 214.0
HSJS2_k127_2486790_3 protein conserved in bacteria K09796 - - 0.000000000000000000000000000009202 124.0
HSJS2_k127_2503299_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.364e-304 940.0
HSJS2_k127_2503299_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 2.359e-204 645.0
HSJS2_k127_2503299_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 439.0
HSJS2_k127_2503299_3 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 314.0
HSJS2_k127_2503299_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000000000005376 213.0
HSJS2_k127_2519279_0 general secretion pathway protein K02459 - - 0.00000000000000000000000000000000000000000000000000000000000008172 221.0
HSJS2_k127_2519279_1 secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000000002459 191.0
HSJS2_k127_2519279_2 general secretion pathway protein K02458 - - 0.000000000000000000000000000000201 131.0
HSJS2_k127_2519279_3 Prokaryotic N-terminal methylation motif K02457 - - 0.0000000000000000000001585 105.0
HSJS2_k127_2519279_4 COG3156 Type II secretory pathway, component PulK K02460 - - 0.0000001493 54.0
HSJS2_k127_2539300_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 343.0
HSJS2_k127_253969_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 496.0
HSJS2_k127_253969_1 COG0515 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000003214 194.0
HSJS2_k127_2559826_0 Putative diguanylate phosphodiesterase K21025 - - 1.985e-282 882.0
HSJS2_k127_2559826_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 609.0
HSJS2_k127_2559826_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 392.0
HSJS2_k127_2559826_3 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 361.0
HSJS2_k127_2559826_4 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007721 342.0
HSJS2_k127_2559826_5 Lysine 2,3-aminomutase YodO family protein K01843,K19810 GO:0003674,GO:0003824,GO:0005488,GO:0016853,GO:0016866,GO:0016869,GO:0048037,GO:0051536,GO:0051539,GO:0051540 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 343.0
HSJS2_k127_2559826_6 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000008707 229.0
HSJS2_k127_2559826_7 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000001876 213.0
HSJS2_k127_2559826_8 TM2 domain - - - 0.0000000000273 76.0
HSJS2_k127_2559826_9 - - - - 0.000749 52.0
HSJS2_k127_2559978_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 574.0
HSJS2_k127_2559978_1 Phosphate starvation-inducible protein PhoH K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 503.0
HSJS2_k127_2559978_2 transporter K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 436.0
HSJS2_k127_2559978_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000000000003469 185.0
HSJS2_k127_2559978_4 proteolysis K19225 - 3.4.21.105 0.00000000000000000000000000000000000002146 161.0
HSJS2_k127_2559978_5 competence protein - - - 0.00002741 48.0
HSJS2_k127_2560451_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008684 555.0
HSJS2_k127_2560451_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 375.0
HSJS2_k127_2560451_2 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000002048 211.0
HSJS2_k127_2560451_3 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000002013 165.0
HSJS2_k127_2563483_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 329.0
HSJS2_k127_2575827_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 6.017e-260 814.0
HSJS2_k127_2575827_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 6.52e-198 626.0
HSJS2_k127_2575827_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 543.0
HSJS2_k127_2575827_3 Lytic murein transglycosylase B K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 391.0
HSJS2_k127_2575827_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000005055 251.0
HSJS2_k127_2575827_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000001296 221.0
HSJS2_k127_2575827_6 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000009077 193.0
HSJS2_k127_2575827_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000000000003633 184.0
HSJS2_k127_2582171_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 515.0
HSJS2_k127_2582171_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 410.0
HSJS2_k127_2582171_2 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007506 269.0
HSJS2_k127_2582171_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001082 246.0
HSJS2_k127_2582171_4 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000000003201 188.0
HSJS2_k127_2582171_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000002111 173.0
HSJS2_k127_2582171_6 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001288 143.0
HSJS2_k127_2582171_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000009006 125.0
HSJS2_k127_2582171_8 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000000003651 93.0
HSJS2_k127_2588720_0 AcnD-accessory protein PrpF K09788 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046459,GO:0071704,GO:0072329,GO:1901575 - 3.651e-203 637.0
HSJS2_k127_2594443_0 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 591.0
HSJS2_k127_2594443_1 protein conserved in bacteria K09781 - - 0.00000000000000000000000000000000000000000000000000037 190.0
HSJS2_k127_2595126_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 491.0
HSJS2_k127_2595126_1 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 460.0
HSJS2_k127_2595126_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 420.0
HSJS2_k127_2595126_3 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 400.0
HSJS2_k127_2595126_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 289.0
HSJS2_k127_2595126_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000000001534 182.0
HSJS2_k127_2595126_6 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K20945 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000435 175.0
HSJS2_k127_2595126_7 protein involved in exopolysaccharide biosynthesis K16554,K16692 - - 0.0000000000000000000000000000001968 128.0
HSJS2_k127_2595126_8 Competence protein ComEA K02237 - - 0.000000000000003558 78.0
HSJS2_k127_2605888_0 Histidine kinase - - - 0.0 1083.0
HSJS2_k127_2612063_0 Fatty acid hydroxylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 365.0
HSJS2_k127_2612063_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000000000000000000000000000000000002046 226.0
HSJS2_k127_2612063_2 sterol desaturase - - - 0.000000000000000000000000000000000000000000000000000007178 199.0
HSJS2_k127_2612063_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0004226 45.0
HSJS2_k127_2631655_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.134e-264 819.0
HSJS2_k127_2631655_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K15576 - - 1.538e-256 795.0
HSJS2_k127_2631655_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K22067 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 487.0
HSJS2_k127_2631655_3 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 451.0
HSJS2_k127_2631655_4 Haloacid dehalogenase-like hydrolase K02566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008448 260.0
HSJS2_k127_2631655_5 ANTAR K07183 - - 0.000000000000000000000000000000000000000000000000000000000000000002126 234.0
HSJS2_k127_2639034_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.077e-266 825.0
HSJS2_k127_2639034_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 0.0000000000000000000000002578 105.0
HSJS2_k127_2644186_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 9.556e-194 622.0
HSJS2_k127_2644186_1 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 441.0
HSJS2_k127_2644186_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 430.0
HSJS2_k127_2644186_3 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 327.0
HSJS2_k127_2644186_4 COG2030 Acyl dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001114 236.0
HSJS2_k127_2644186_5 Protein of unknown function (DUF2505) - - - 0.00000000000000000000000000000000002817 140.0
HSJS2_k127_2644186_6 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000005135 99.0
HSJS2_k127_2644186_7 Acyl-CoA dehydrogenase N terminal - - - 0.00000000000004698 74.0
HSJS2_k127_2644186_8 Putative prokaryotic signal transducing protein - - - 0.0000000001858 67.0
HSJS2_k127_2645253_0 Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate K00265 - 1.4.1.13,1.4.1.14 0.0 1287.0
HSJS2_k127_2645421_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 529.0
HSJS2_k127_2645421_1 DUF218 domain - - - 0.00000000000000000000000000000000000000000000000000007604 193.0
HSJS2_k127_2645421_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000003029 154.0
HSJS2_k127_2645421_3 competence protein - - - 0.00000000000000000000000000000001686 142.0
HSJS2_k127_2652990_0 Bacterial Ig-like domain - - - 0.0 1642.0
HSJS2_k127_2652990_1 flavoprotein involved in K transport - - - 3.655e-295 909.0
HSJS2_k127_2652990_10 Domain of unknown function (DUF4872) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 471.0
HSJS2_k127_2652990_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 451.0
HSJS2_k127_2652990_12 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 387.0
HSJS2_k127_2652990_13 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000004587 188.0
HSJS2_k127_2652990_14 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000008516 158.0
HSJS2_k127_2652990_15 transcriptional regulator - - - 0.00000000000000000000000000000000001579 136.0
HSJS2_k127_2652990_2 Belongs to the GMC oxidoreductase family - - - 3.539e-285 882.0
HSJS2_k127_2652990_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 2.184e-282 873.0
HSJS2_k127_2652990_4 COG2067 Long-chain fatty acid transport protein - - - 3.451e-246 764.0
HSJS2_k127_2652990_5 acyl-CoA dehydrogenase - - - 3.544e-216 674.0
HSJS2_k127_2652990_6 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 576.0
HSJS2_k127_2652990_7 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 569.0
HSJS2_k127_2652990_8 Metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007396 515.0
HSJS2_k127_2652990_9 Metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 477.0
HSJS2_k127_2656160_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1139.0
HSJS2_k127_2656160_1 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 309.0
HSJS2_k127_2656160_2 stress-induced protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 304.0
HSJS2_k127_2656160_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 286.0
HSJS2_k127_2656160_4 endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000004485 202.0
HSJS2_k127_2656160_5 transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000009327 191.0
HSJS2_k127_2656160_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000000007831 143.0
HSJS2_k127_2658245_0 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 601.0
HSJS2_k127_2658245_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 369.0
HSJS2_k127_2658245_2 Bacterial protein of unknown function (DUF924) - - - 0.00000000000000000000000002716 110.0
HSJS2_k127_26607_0 exodeoxyribonuclease III K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 442.0
HSJS2_k127_26607_1 Preprotein translocase subunit SecA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 410.0
HSJS2_k127_26607_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 362.0
HSJS2_k127_26607_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001215 260.0
HSJS2_k127_26607_4 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000000006345 206.0
HSJS2_k127_26607_5 COG0515 Serine threonine protein kinase - - - 0.00000000000000000000000000000000005334 135.0
HSJS2_k127_26607_6 COG2030 Acyl dehydratase - - - 0.000000000000000000000000000000001391 131.0
HSJS2_k127_2671644_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1061.0
HSJS2_k127_2671644_1 can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli K11105 - - 2.249e-213 676.0
HSJS2_k127_2671644_2 Chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 461.0
HSJS2_k127_2671644_3 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000006829 233.0
HSJS2_k127_2671644_4 Region found in RelA / SpoT proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000006913 231.0
HSJS2_k127_267513_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1082.0
HSJS2_k127_267513_1 flavoprotein involved in K transport - - - 3.892e-254 792.0
HSJS2_k127_267513_10 hydrolase K20862 - 3.1.3.102,3.1.3.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 278.0
HSJS2_k127_267513_11 May be involved in the biosynthesis of molybdopterin K03638 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0042802,GO:0044424,GO:0044444,GO:0044464 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000002368 253.0
HSJS2_k127_267513_12 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001742 247.0
HSJS2_k127_267513_13 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000002287 216.0
HSJS2_k127_267513_14 Uncharacterized protein conserved in bacteria (DUF2057) K09909 - - 0.00000000000000000000000000000000000000000000000000001814 196.0
HSJS2_k127_267513_15 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000002482 168.0
HSJS2_k127_267513_16 transcriptional regulator K19591 - - 0.000000000000000000000000000000000000000000004677 166.0
HSJS2_k127_267513_17 Protein of unknown function (DUF523) - - - 0.000000000000000000000000000000000000000002684 163.0
HSJS2_k127_267513_18 protein conserved in bacteria - - - 0.0000000000000000000000000000000002512 136.0
HSJS2_k127_267513_19 membrane - - - 0.00000000000000000000000001052 112.0
HSJS2_k127_267513_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 1.807e-197 623.0
HSJS2_k127_267513_20 BPTI/Kunitz family of serine protease inhibitors. - - - 0.0000000000000000000002158 100.0
HSJS2_k127_267513_3 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 7.631e-197 621.0
HSJS2_k127_267513_4 alcohol dehydrogenase K08325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 608.0
HSJS2_k127_267513_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 560.0
HSJS2_k127_267513_6 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 458.0
HSJS2_k127_267513_7 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 366.0
HSJS2_k127_267513_8 COG0303 Molybdopterin biosynthesis enzyme K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 366.0
HSJS2_k127_267513_9 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 325.0
HSJS2_k127_2680998_0 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 334.0
HSJS2_k127_2680998_1 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000007326 208.0
HSJS2_k127_2680998_2 Domain of unknown function (DUF4189) - - - 0.00000000000000000000000001652 118.0
HSJS2_k127_2693257_0 Flavodoxin K00380 - 1.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000008632 259.0
HSJS2_k127_2693257_1 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000137 248.0
HSJS2_k127_2693257_2 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
HSJS2_k127_2693257_3 Biopolymer transport protein ExbD/TolR K03559 - - 0.00000000000000000000000000000000000000000006127 164.0
HSJS2_k127_2693257_4 TonB C terminal K03832 - - 0.00000000000000000000000000003529 127.0
HSJS2_k127_270988_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009987 302.0
HSJS2_k127_270988_1 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000004155 223.0
HSJS2_k127_270988_2 Flavin-binding monooxygenase-like K03379 - 1.14.13.22 0.000000000000000000000000000000007978 130.0
HSJS2_k127_2720364_0 PFAM Peptidase C13 - - - 0.0000000000000000000000000000000000000000000000000000001369 207.0
HSJS2_k127_2720364_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000008576 194.0
HSJS2_k127_2720364_2 Domain of unknown function (DUF4034) - - - 0.00002222 56.0
HSJS2_k127_2724057_0 COG3555 Aspartyl asparaginyl beta-hydroxylase and related dioxygenases K12979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 504.0
HSJS2_k127_2724057_1 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 371.0
HSJS2_k127_2724057_2 Predicted metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 330.0
HSJS2_k127_2724057_3 AraC family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001133 269.0
HSJS2_k127_2724057_4 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002911 258.0
HSJS2_k127_2724057_5 Outer Membrane Lipoprotein - - - 0.0000000000000000000000000000000000008852 149.0
HSJS2_k127_2724057_6 - - - - 0.0000000000000000006966 91.0
HSJS2_k127_2724057_7 - - - - 0.00001025 51.0
HSJS2_k127_2724238_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 5.122e-269 832.0
HSJS2_k127_2724238_1 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 9.977e-234 728.0
HSJS2_k127_2724238_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 3.51e-229 713.0
HSJS2_k127_2724238_3 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.927e-224 711.0
HSJS2_k127_2724238_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 5.675e-209 658.0
HSJS2_k127_2724238_5 Acyl-CoA thioesterase K10805 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006596 423.0
HSJS2_k127_2724238_6 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 410.0
HSJS2_k127_2724238_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 377.0
HSJS2_k127_2724238_8 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003668 353.0
HSJS2_k127_2724238_9 Uracil-DNA glycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004531 264.0
HSJS2_k127_2727040_0 Iron permease FTR1 family K07243 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 497.0
HSJS2_k127_2727040_1 - - - - 0.00000000000000000000000000000006671 127.0
HSJS2_k127_2727040_2 rhs family - - - 0.0000000001998 61.0
HSJS2_k127_272820_0 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 402.0
HSJS2_k127_272820_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 379.0
HSJS2_k127_272820_2 COG0811 Biopolymer transport proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002713 278.0
HSJS2_k127_272820_3 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000008372 185.0
HSJS2_k127_272820_4 biopolymer transport protein - - - 0.000000000000000000000000000000000000000000000004486 177.0
HSJS2_k127_272820_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000004052 167.0
HSJS2_k127_272820_6 - - - - 0.000000000000000000000000003103 113.0
HSJS2_k127_2742419_0 found to be peripherally associated with the inner membrane in Escherichia coli K03499 - - 1.931e-251 780.0
HSJS2_k127_2742419_1 Fatty acid desaturase K00496 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 2.37e-200 630.0
HSJS2_k127_2742419_10 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000982 257.0
HSJS2_k127_2742419_11 FAD linked oxidase - - - 0.00000000000000000000000000000000000000000000078 166.0
HSJS2_k127_2742419_2 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022803,GO:0022838,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031224,GO:0031226,GO:0031420,GO:0034220,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046983,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 543.0
HSJS2_k127_2742419_3 protein containing LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 426.0
HSJS2_k127_2742419_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 407.0
HSJS2_k127_2742419_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 368.0
HSJS2_k127_2742419_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009383,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 347.0
HSJS2_k127_2742419_7 Rossmann fold nucleotide-binding protein involved in DNA uptake K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 312.0
HSJS2_k127_2742419_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 291.0
HSJS2_k127_2742419_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005554 278.0
HSJS2_k127_2749885_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 456.0
HSJS2_k127_2749885_1 seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing K05808 - - 0.00000000000000000000000000000000000000000000000007002 178.0
HSJS2_k127_2749885_2 PTS fructose transporter subunit IIA K02806 - - 0.000001696 50.0
HSJS2_k127_2750774_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 543.0
HSJS2_k127_2750774_1 - - - - 0.000005201 55.0
HSJS2_k127_2752526_0 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 341.0
HSJS2_k127_2752526_1 Sugar ABC transporter substrate-binding protein K01991 - - 0.000000000000000000000000000000000000000000000000000000000000003406 222.0
HSJS2_k127_2752526_2 DnaJ domain K09510 - - 0.000004273 57.0
HSJS2_k127_2752942_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1123.0
HSJS2_k127_2752942_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 2.427e-274 851.0
HSJS2_k127_2752942_10 sorbosone dehydrogenase - - - 0.0000000000000000000000000001493 117.0
HSJS2_k127_2752942_2 flavoprotein involved in K transport - - - 5.086e-240 750.0
HSJS2_k127_2752942_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 6.705e-235 731.0
HSJS2_k127_2752942_4 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 7.164e-233 728.0
HSJS2_k127_2752942_5 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 557.0
HSJS2_k127_2752942_6 Predicted metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 430.0
HSJS2_k127_2752942_7 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 409.0
HSJS2_k127_2752942_8 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 348.0
HSJS2_k127_2752942_9 COG0695 Glutaredoxin and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 323.0
HSJS2_k127_275449_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.0 1579.0
HSJS2_k127_275449_1 Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01886 - 6.1.1.18 2.164e-281 872.0
HSJS2_k127_275449_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 499.0
HSJS2_k127_275449_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 351.0
HSJS2_k127_275449_4 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 327.0
HSJS2_k127_275449_5 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 323.0
HSJS2_k127_275449_6 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002999 269.0
HSJS2_k127_275449_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
HSJS2_k127_275449_8 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000114 171.0
HSJS2_k127_275449_9 - - - - 0.00006318 45.0
HSJS2_k127_2760560_0 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 481.0
HSJS2_k127_2760560_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 313.0
HSJS2_k127_2760560_2 - - - - 0.000000000000000000000000000000000000000000000000000000000001409 215.0
HSJS2_k127_2760560_3 Acyl-CoA-binding protein - - - 0.00000000000000000000000000000000009124 134.0
HSJS2_k127_2782490_0 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 462.0
HSJS2_k127_2782490_1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000007419 237.0
HSJS2_k127_2782490_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000003987 88.0
HSJS2_k127_2792174_0 COG4206 Outer membrane cobalamin receptor protein K16092 - - 1.653e-272 851.0
HSJS2_k127_2792174_1 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase K02225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 363.0
HSJS2_k127_2792174_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000003969 258.0
HSJS2_k127_2792174_3 COG0614 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000000000000002747 171.0
HSJS2_k127_2816961_0 Short chain dehydrogenase - - - 3.354e-207 660.0
HSJS2_k127_2816961_1 COG1960 Acyl-CoA dehydrogenases K06445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 480.0
HSJS2_k127_2816961_2 Esterase lipase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008917 449.0
HSJS2_k127_2816961_3 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 427.0
HSJS2_k127_2816961_4 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 315.0
HSJS2_k127_2816961_5 Belongs to the globin family - - - 0.000000000000000000000000000000000000000000000000000000008789 201.0
HSJS2_k127_2816961_6 Metallopeptidase family M24 - - - 0.00000000000000000000000000006347 127.0
HSJS2_k127_2816961_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000005661 99.0
HSJS2_k127_2824123_0 belongs to the carbohydrate kinase PfkB family K00847,K00892 - 2.7.1.4,2.7.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 327.0
HSJS2_k127_2824123_1 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000002015 173.0
HSJS2_k127_2824123_2 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000001285 163.0
HSJS2_k127_2830470_0 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000355 192.0
HSJS2_k127_2830470_2 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000001364 109.0
HSJS2_k127_2848715_0 ATP-dependent helicase HrpB K03579 - 3.6.4.13 9.088e-229 734.0
HSJS2_k127_2848715_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002374 278.0
HSJS2_k127_2848715_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000059 267.0
HSJS2_k127_285583_0 exporters of the RND superfamily K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 461.0
HSJS2_k127_285583_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 381.0
HSJS2_k127_285583_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000049 339.0
HSJS2_k127_285583_3 membrane K08974 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 341.0
HSJS2_k127_285583_4 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 287.0
HSJS2_k127_285583_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 GO:0003674,GO:0003824,GO:0004309,GO:0005488,GO:0005515,GO:0006139,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008254,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009125,GO:0009129,GO:0009131,GO:0009158,GO:0009161,GO:0009164,GO:0009166,GO:0009173,GO:0009175,GO:0009218,GO:0009222,GO:0009259,GO:0009261,GO:0009987,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030145,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0042578,GO:0042802,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046049,GO:0046050,GO:0046131,GO:0046133,GO:0046135,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000002568 231.0
HSJS2_k127_2860441_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1425.0
HSJS2_k127_2860441_1 Belongs to the glutamate synthase family - - - 2.599e-241 754.0
HSJS2_k127_2860441_10 protein, possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002611 240.0
HSJS2_k127_2860441_11 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000000000005622 202.0
HSJS2_k127_2860441_13 Protein of unknown function (DUF805) - - - 0.000000000000000000000000000000001081 138.0
HSJS2_k127_2860441_14 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.000000000000000000000000005113 113.0
HSJS2_k127_2860441_15 Protein of unknown function (DUF1232) - - - 0.00000000000000000000001013 105.0
HSJS2_k127_2860441_2 P-aminobenzoate N-oxygenase AurF - - - 1.775e-209 655.0
HSJS2_k127_2860441_3 COG3243 Poly(3-hydroxyalkanoate) synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000759 570.0
HSJS2_k127_2860441_4 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 571.0
HSJS2_k127_2860441_5 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 426.0
HSJS2_k127_2860441_6 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 415.0
HSJS2_k127_2860441_7 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 346.0
HSJS2_k127_2860441_8 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001435 259.0
HSJS2_k127_2860441_9 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007383 245.0
HSJS2_k127_2879811_0 acyl-CoA dehydrogenase - - - 0.0 1039.0
HSJS2_k127_2879811_1 acyl-CoA dehydrogenase - - - 2.188e-245 762.0
HSJS2_k127_2879811_2 Phospholipase K01058 - 3.1.1.32,3.1.1.4 0.000000000000000000000000000000000000000000000000000000006318 206.0
HSJS2_k127_2879811_3 Trm112p-like protein K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000003472 93.0
HSJS2_k127_2883410_0 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000000000000000000000000769 224.0
HSJS2_k127_2883410_1 Effector of murein hydrolase LrgA K05338,K06518 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0008565,GO:0009056,GO:0009057,GO:0009253,GO:0015031,GO:0015833,GO:0016020,GO:0030203,GO:0033036,GO:0042886,GO:0043170,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000002447 126.0
HSJS2_k127_2883410_2 effector of murein hydrolase - - - 0.0000000002981 64.0
HSJS2_k127_2886979_0 Gluconolactonase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000935 501.0
HSJS2_k127_2886979_1 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 389.0
HSJS2_k127_2886979_2 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.0000000000000000000000000000000000000000000000000000001053 198.0
HSJS2_k127_2886979_3 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000002971 149.0
HSJS2_k127_2886979_4 - - - - 0.000000000000000343 88.0
HSJS2_k127_2892243_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001683 468.0
HSJS2_k127_2892243_1 COG0084 Mg-dependent DNase K03424 - - 0.000000000000000000000000000001036 123.0
HSJS2_k127_2892243_2 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000003796 75.0
HSJS2_k127_2895759_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 7.35e-216 674.0
HSJS2_k127_2903591_0 macromolecule glycosylation - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000007349 232.0
HSJS2_k127_2903591_1 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000000000000000000005954 159.0
HSJS2_k127_2912808_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 566.0
HSJS2_k127_2912808_1 Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 477.0
HSJS2_k127_2912808_2 diguanylate cyclase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001279 293.0
HSJS2_k127_2912808_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005905 244.0
HSJS2_k127_2912808_4 START domain - - - 0.0000000000000000000000000000000000000000001219 169.0
HSJS2_k127_2912808_5 COG0695 Glutaredoxin and related proteins - - - 0.000000000000000000000000000000000000000002244 160.0
HSJS2_k127_2912808_6 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000000000000000000000000000005864 133.0
HSJS2_k127_2912808_7 Histidine kinase K07315 - 3.1.3.3 0.00000006728 58.0
HSJS2_k127_2913939_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 550.0
HSJS2_k127_2913939_1 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 360.0
HSJS2_k127_2913939_2 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 338.0
HSJS2_k127_2913939_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000146 199.0
HSJS2_k127_2913939_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000008858 128.0
HSJS2_k127_2913939_5 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000005323 128.0
HSJS2_k127_2913939_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000002632 52.0
HSJS2_k127_2914304_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 6.007e-238 743.0
HSJS2_k127_2914304_1 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 365.0
HSJS2_k127_2935532_0 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 319.0
HSJS2_k127_2935532_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004386 268.0
HSJS2_k127_2935532_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000611 260.0
HSJS2_k127_2935532_3 Protein of unknown function (DUF3047) - - - 0.0000000000000000000000000000000000000000000000000003572 192.0
HSJS2_k127_2940363_0 BFD-like [2Fe-2S] binding domain K00362 - 1.7.1.15 2.179e-224 715.0
HSJS2_k127_2940363_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007329 555.0
HSJS2_k127_2940363_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 482.0
HSJS2_k127_2940363_3 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 457.0
HSJS2_k127_2941735_0 Domain of unknown function (DUF4331) - - - 3.124e-254 789.0
HSJS2_k127_2941735_1 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 2.767e-212 666.0
HSJS2_k127_2941735_10 - - - - 0.0000000005498 63.0
HSJS2_k127_2941735_2 Aminotransferase class-III K00836 - 2.6.1.76 1.937e-203 640.0
HSJS2_k127_2941735_3 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 7.145e-197 623.0
HSJS2_k127_2941735_4 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 529.0
HSJS2_k127_2941735_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
HSJS2_k127_2941735_6 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 309.0
HSJS2_k127_2941735_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001307 248.0
HSJS2_k127_2941735_8 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000004031 231.0
HSJS2_k127_2941735_9 - - - - 0.00000000000000000000005115 106.0
HSJS2_k127_2949365_0 COG1305 Transglutaminase-like enzymes K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 556.0
HSJS2_k127_2949365_1 ATPase, AAA K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 423.0
HSJS2_k127_2949365_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 363.0
HSJS2_k127_2949365_3 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 295.0
HSJS2_k127_2953028_0 endonuclease I K01150 - 3.1.21.1 0.00000000000000000000000000000000000000000000000000000000177 206.0
HSJS2_k127_2953028_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000004535 171.0
HSJS2_k127_2959028_0 MMPL family K07003 - - 1.465e-207 672.0
HSJS2_k127_2972440_0 glycosyl transferase group 1 K03208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002114 541.0
HSJS2_k127_2972440_1 epimerase dehydratase K02473,K17947 - 5.1.3.25,5.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 531.0
HSJS2_k127_2972440_2 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 498.0
HSJS2_k127_2972440_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 426.0
HSJS2_k127_2972440_4 Polysaccharide biosynthesis protein K17716 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 415.0
HSJS2_k127_2972440_5 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 368.0
HSJS2_k127_2972440_6 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000004721 159.0
HSJS2_k127_2989128_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03314 - - 1.238e-234 737.0
HSJS2_k127_2989128_1 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 2.835e-215 686.0
HSJS2_k127_2989128_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000009754 242.0
HSJS2_k127_2989128_11 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000009333 195.0
HSJS2_k127_2989128_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 6.906e-205 650.0
HSJS2_k127_2989128_3 Histidine kinase - - - 7.631e-195 623.0
HSJS2_k127_2989128_4 peptidase K04774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 435.0
HSJS2_k127_2989128_5 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 410.0
HSJS2_k127_2989128_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 310.0
HSJS2_k127_2989128_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000841 280.0
HSJS2_k127_2989128_8 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004261 279.0
HSJS2_k127_2989128_9 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000001613 269.0
HSJS2_k127_2989152_0 Fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 508.0
HSJS2_k127_2989152_1 alginic acid biosynthetic process K01729 - 4.2.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 520.0
HSJS2_k127_2989152_2 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 461.0
HSJS2_k127_2989152_3 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000937 183.0
HSJS2_k127_2989152_4 polysaccharide catabolic process K01179,K01218 - 3.2.1.4,3.2.1.78 0.000000000000000778 92.0
HSJS2_k127_2989152_5 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000158 64.0
HSJS2_k127_2989152_6 intracellular chloride channel activity K05027,K05030 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005215,GO:0005216,GO:0005229,GO:0005253,GO:0005254,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005887,GO:0005902,GO:0006508,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006821,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008509,GO:0012505,GO:0012506,GO:0015075,GO:0015103,GO:0015108,GO:0015267,GO:0015276,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0016324,GO:0016787,GO:0019538,GO:0022803,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022857,GO:0030141,GO:0030659,GO:0030667,GO:0031090,GO:0031224,GO:0031226,GO:0031410,GO:0031982,GO:0034220,GO:0042588,GO:0042589,GO:0042995,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0044238,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045177,GO:0051179,GO:0051234,GO:0055085,GO:0061778,GO:0070011,GO:0071704,GO:0071944,GO:0097708,GO:0098588,GO:0098590,GO:0098656,GO:0098660,GO:0098661,GO:0098805,GO:0098858,GO:0099503,GO:0120025,GO:0140096,GO:1901564,GO:1902476 - 0.00000105 62.0
HSJS2_k127_2998760_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 370.0
HSJS2_k127_2998760_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.00000000000000000000000000000000000000000001815 164.0
HSJS2_k127_2998760_2 membrane K07058 - - 0.000000000000000000000000000000000002666 141.0
HSJS2_k127_2998760_3 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000236 89.0
HSJS2_k127_3000345_0 fatty acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 481.0
HSJS2_k127_3000345_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 385.0
HSJS2_k127_3000345_2 (Lipo)protein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003095 310.0
HSJS2_k127_3000345_3 DoxX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002389 253.0
HSJS2_k127_3000345_4 protein conserved in bacteria K09929 - - 0.000000000000000000000000000000000000000000000000000001717 197.0
HSJS2_k127_3000345_5 protein conserved in bacteria - - - 0.0000000000000000000000000005645 118.0
HSJS2_k127_3005374_0 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007909 487.0
HSJS2_k127_3005374_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000001719 202.0
HSJS2_k127_3005374_2 CorA-like Mg2+ transporter protein K16074 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0015562,GO:0016020,GO:0016021,GO:0022857,GO:0022883,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046583,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000001131 167.0
HSJS2_k127_3013277_0 Pfam:HipA_N K07154 - 2.7.11.1 2.271e-220 688.0
HSJS2_k127_3013277_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 4.962e-202 634.0
HSJS2_k127_3013277_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 432.0
HSJS2_k127_3013277_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 297.0
HSJS2_k127_3013277_4 Belongs to the 'phage' integrase family - - - 0.00000000000145 69.0
HSJS2_k127_3016415_0 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 497.0
HSJS2_k127_3016415_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 473.0
HSJS2_k127_3016415_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000001222 241.0
HSJS2_k127_3025943_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 480.0
HSJS2_k127_3025943_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 482.0
HSJS2_k127_3048850_0 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 388.0
HSJS2_k127_3048850_1 thiol-disulphide oxidoreductase DCC - - - 0.00000000000000000000000000000001854 133.0
HSJS2_k127_3048850_2 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000005129 80.0
HSJS2_k127_3052019_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.351e-216 681.0
HSJS2_k127_3052019_1 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000000000007131 211.0
HSJS2_k127_3052019_2 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000007185 124.0
HSJS2_k127_3056569_0 Histidine kinase - - - 0.0 1337.0
HSJS2_k127_3056569_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 553.0
HSJS2_k127_3056569_10 MFS transporter - - - 0.00000000000000000000001213 103.0
HSJS2_k127_3056569_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 488.0
HSJS2_k127_3056569_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 359.0
HSJS2_k127_3056569_4 COG1428 Deoxynucleoside kinases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 319.0
HSJS2_k127_3056569_5 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 304.0
HSJS2_k127_3056569_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004287 285.0
HSJS2_k127_3056569_7 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000169 277.0
HSJS2_k127_3056569_8 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000001731 231.0
HSJS2_k127_3056569_9 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 0.000000000000000000000000000000000000004482 152.0
HSJS2_k127_3063254_0 ABC1 family protein, ubiquinone biosynthesis protein K03688 - - 1.211e-252 789.0
HSJS2_k127_3063254_1 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 492.0
HSJS2_k127_3063254_2 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 331.0
HSJS2_k127_3063254_3 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 305.0
HSJS2_k127_3063254_4 COG2230 Cyclopropane fatty acid synthase and related methyltransferases - - - 0.000000000000000000000000000000000000000000000000000000000000000003617 233.0
HSJS2_k127_3063254_5 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000004204 201.0
HSJS2_k127_3063254_6 PFAM Transposase - - - 0.0000000000000000000002405 99.0
HSJS2_k127_3065802_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.556e-237 740.0
HSJS2_k127_3065802_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000006612 198.0
HSJS2_k127_3065802_2 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000001178 76.0
HSJS2_k127_3072844_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1577.0
HSJS2_k127_3072844_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 501.0
HSJS2_k127_3072844_2 consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 382.0
HSJS2_k127_3072844_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07639,K18072 - 2.7.13.3 0.0007961 44.0
HSJS2_k127_3075687_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 379.0
HSJS2_k127_3075687_1 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000006411 255.0
HSJS2_k127_3075687_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000001044 85.0
HSJS2_k127_3086419_0 Domain of unknown function (DUF4105) - - - 5.149e-224 710.0
HSJS2_k127_3086419_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 406.0
HSJS2_k127_3086419_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003783 346.0
HSJS2_k127_3086419_3 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 348.0
HSJS2_k127_3086419_4 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002397 238.0
HSJS2_k127_3086419_5 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000703 170.0
HSJS2_k127_3086419_6 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.000000000000000000000000000000000000000006096 158.0
HSJS2_k127_3086419_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000001288 106.0
HSJS2_k127_3086419_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000001421 87.0
HSJS2_k127_3086419_9 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.00000000000001639 74.0
HSJS2_k127_3087399_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 359.0
HSJS2_k127_3087399_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005112 318.0
HSJS2_k127_3087399_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000000004725 235.0
HSJS2_k127_3087399_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.00000000001094 67.0
HSJS2_k127_3087399_4 Uncharacterised protein family UPF0047 - - - 0.0001056 46.0
HSJS2_k127_3092190_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 3.814e-227 713.0
HSJS2_k127_3092190_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 566.0
HSJS2_k127_3092190_10 Bacterial regulatory proteins, tetR family - - - 0.000000002898 66.0
HSJS2_k127_3092190_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 533.0
HSJS2_k127_3092190_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003721 492.0
HSJS2_k127_3092190_4 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 305.0
HSJS2_k127_3092190_5 fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005334 250.0
HSJS2_k127_3092190_6 Uncharacterized lipoprotein K07286 - - 0.0000000000000000000000000000000000000000000000000005874 190.0
HSJS2_k127_3092190_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000002206 173.0
HSJS2_k127_3092190_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000000004898 152.0
HSJS2_k127_3092190_9 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000001041 138.0
HSJS2_k127_309582_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 2.306e-289 907.0
HSJS2_k127_309582_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008314 242.0
HSJS2_k127_309582_2 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000006291 191.0
HSJS2_k127_309582_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000763 126.0
HSJS2_k127_3095823_0 Belongs to the selenophosphate synthase 1 family. Class I subfamily K01008 - 2.7.9.3 2.411e-203 657.0
HSJS2_k127_3095823_1 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 545.0
HSJS2_k127_3095823_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 485.0
HSJS2_k127_3095823_3 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 404.0
HSJS2_k127_3095823_4 PhzC PhzF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 306.0
HSJS2_k127_3095823_5 ABC transporter, ATP-binding protein K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000182 259.0
HSJS2_k127_3095823_6 transcriptional regulator - - - 0.000000000000000000000000000000000000000000005026 168.0
HSJS2_k127_3095823_7 - - - - 0.0000000000000000000000000000000000002951 143.0
HSJS2_k127_3095823_8 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000000000000000009807 91.0
HSJS2_k127_3095823_9 Transcriptional regulators - - - 0.000000002994 59.0
HSJS2_k127_3098553_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1449.0
HSJS2_k127_3098553_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 545.0
HSJS2_k127_3098553_10 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000002894 219.0
HSJS2_k127_3098553_11 Peptidoglycan-binding protein, CsiV - - - 0.0000000000000000000000000000000000001494 153.0
HSJS2_k127_3098553_12 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000001351 52.0
HSJS2_k127_3098553_2 flavoproteins K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 538.0
HSJS2_k127_3098553_3 mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 491.0
HSJS2_k127_3098553_4 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 396.0
HSJS2_k127_3098553_5 Outer membrane lipoprotein-sorting protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005874 382.0
HSJS2_k127_3098553_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 332.0
HSJS2_k127_3098553_7 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000669 284.0
HSJS2_k127_3098553_8 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000004336 262.0
HSJS2_k127_3098553_9 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000003929 233.0
HSJS2_k127_3100602_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.31e-289 892.0
HSJS2_k127_3104153_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00800 - 1.3.1.12,2.5.1.19 0.0 1093.0
HSJS2_k127_3104153_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 2.549e-302 933.0
HSJS2_k127_3104153_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 375.0
HSJS2_k127_3104153_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 341.0
HSJS2_k127_3116016_0 Pyridine nucleotide-disulphide oxidoreductase K00362,K05297 - 1.18.1.1,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 404.0
HSJS2_k127_3116016_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 397.0
HSJS2_k127_3116016_2 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.000000000000000000000000000000000000000000000000004757 183.0
HSJS2_k127_3116016_3 Nitrite reductase K00363 - 1.7.1.15 0.0000000000000000000000000000000000000000698 153.0
HSJS2_k127_3116178_0 Amidohydrolase family - - - 3.685e-254 795.0
HSJS2_k127_3116178_1 COG2207 AraC-type DNA-binding domain-containing proteins - - - 3.917e-198 620.0
HSJS2_k127_3116178_10 PFAM transposase IS111A IS1328 IS1533, transposase IS116 IS110 IS902 family protein - - - 0.00001516 49.0
HSJS2_k127_3116178_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 582.0
HSJS2_k127_3116178_3 diguanylate cyclase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 586.0
HSJS2_k127_3116178_4 sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 561.0
HSJS2_k127_3116178_5 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 444.0
HSJS2_k127_3116178_6 Protein of unknown function (DUF2505) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000147 273.0
HSJS2_k127_3116178_7 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000241 260.0
HSJS2_k127_3116178_8 LuxR family transcriptional regulator - - - 0.000000000000000000000000000000000000000003659 165.0
HSJS2_k127_3116178_9 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000006576 141.0
HSJS2_k127_3116745_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 566.0
HSJS2_k127_3116745_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 546.0
HSJS2_k127_3116745_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 477.0
HSJS2_k127_3116745_3 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 292.0
HSJS2_k127_3116745_4 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001018 286.0
HSJS2_k127_3125118_0 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009188 516.0
HSJS2_k127_3125118_1 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 481.0
HSJS2_k127_3125118_10 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000008756 134.0
HSJS2_k127_3125118_11 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000009933 126.0
HSJS2_k127_3125118_12 PilZ domain - - - 0.00000000007618 68.0
HSJS2_k127_3125118_2 Cyclopropane fatty acid synthase and related K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 441.0
HSJS2_k127_3125118_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 421.0
HSJS2_k127_3125118_4 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 421.0
HSJS2_k127_3125118_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 369.0
HSJS2_k127_3125118_6 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 322.0
HSJS2_k127_3125118_7 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 316.0
HSJS2_k127_3125118_8 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 285.0
HSJS2_k127_3125118_9 ketosteroid isomerase - - - 0.0000000000000000000000000000000000255 143.0
HSJS2_k127_3125437_0 COG0659 Sulfate permease and related transporters (MFS superfamily) K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 369.0
HSJS2_k127_3125437_1 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 326.0
HSJS2_k127_3125437_2 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000000000000003158 209.0
HSJS2_k127_3133114_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1026.0
HSJS2_k127_3136160_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 6.65e-286 883.0
HSJS2_k127_3136160_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 8.152e-229 711.0
HSJS2_k127_3136160_10 Sporulation related domain K03749 - - 0.000000000000000000000000000007392 127.0
HSJS2_k127_3136160_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 9.897e-199 625.0
HSJS2_k127_3136160_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 496.0
HSJS2_k127_3136160_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 384.0
HSJS2_k127_3136160_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 349.0
HSJS2_k127_3136160_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 336.0
HSJS2_k127_3136160_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000003675 250.0
HSJS2_k127_3136160_8 colicin V production K03558 - - 0.0000000000000000000000000000000000000000000000000000000000000000002271 234.0
HSJS2_k127_3136160_9 ATPase, AAA K03924 - - 0.000000000000000000000000000002083 121.0
HSJS2_k127_3145738_0 ABC-type oligopeptide transport system, periplasmic component K13893 - - 9.625e-201 637.0
HSJS2_k127_3145738_1 With YejAEF is involved in resistance to microcin C K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 562.0
HSJS2_k127_3145738_2 ABC transporter permease K13895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 560.0
HSJS2_k127_3145738_3 Belongs to the ABC transporter superfamily K13896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000549 246.0
HSJS2_k127_3158499_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 424.0
HSJS2_k127_3160113_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 7.78e-269 849.0
HSJS2_k127_3160113_1 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002534 567.0
HSJS2_k127_3160113_2 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 493.0
HSJS2_k127_3160113_3 phosphotransferase related to Ser Thr protein K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 462.0
HSJS2_k127_3160113_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 425.0
HSJS2_k127_3160113_5 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000056 393.0
HSJS2_k127_3160113_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 338.0
HSJS2_k127_3160113_7 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 319.0
HSJS2_k127_3160113_8 protein affecting Mg2 Co2 transport K06195 - - 0.0000000000000000000000000000000000000000000000000000000004175 203.0
HSJS2_k127_3166328_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000514 481.0
HSJS2_k127_3166328_1 metal-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 409.0
HSJS2_k127_3166328_2 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 323.0
HSJS2_k127_3168489_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 2.018e-208 655.0
HSJS2_k127_3168489_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046429,GO:0046490,GO:0046872,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 511.0
HSJS2_k127_3168489_2 protein conserved in bacteria K15539 - - 0.0000000000000000000000000000000000000000007399 168.0
HSJS2_k127_3168489_3 COG3063 Tfp pilus assembly protein PilF K02656 - - 0.000000000000000000000000000000000000000398 154.0
HSJS2_k127_31729_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 406.0
HSJS2_k127_31729_1 COG3156 Type II secretory pathway, component PulK K02460 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 307.0
HSJS2_k127_31729_2 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.00000000000000000000000000000000000000000000000000000007199 209.0
HSJS2_k127_31729_3 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.0000000000000000000000000000009095 127.0
HSJS2_k127_3172964_0 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 0.0 1049.0
HSJS2_k127_3172964_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 1.335e-194 618.0
HSJS2_k127_3172964_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 315.0
HSJS2_k127_3172964_3 transcriptional regulator K22105 - - 0.00000000000000000000000000000000000000000000000000003541 196.0
HSJS2_k127_3172964_4 - - - - 0.0000000000000000000000000000000000001447 154.0
HSJS2_k127_3173553_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 585.0
HSJS2_k127_3173553_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000008086 147.0
HSJS2_k127_3178276_0 tonB-system energizer ExbB K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003444 265.0
HSJS2_k127_3178276_1 Biopolymer transport protein K03559 - - 0.00000000000000000000000000000000000000000003594 164.0
HSJS2_k127_3187381_0 Type II and III secretion system protein K02507,K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 381.0
HSJS2_k127_3187381_1 Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000001561 241.0
HSJS2_k127_3187381_2 Type 4 fimbrial biogenesis protein PilP K02665 - - 0.000000000000000000000000000000000000000000000000000000000002415 213.0
HSJS2_k127_3197138_0 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 349.0
HSJS2_k127_3197138_1 hemolysin III K11068 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 293.0
HSJS2_k127_3197138_2 secreted trypsin-like serine protease K01325 - 3.4.21.35 0.00000000000000000000000001454 125.0
HSJS2_k127_3210061_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 554.0
HSJS2_k127_3210061_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 407.0
HSJS2_k127_3210061_2 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 372.0
HSJS2_k127_3215252_0 Belongs to the DEAD box helicase family K05591 GO:0000027,GO:0000166,GO:0003674,GO:0003676,GO:0003723,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008144,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0033677,GO:0034458,GO:0034459,GO:0034622,GO:0034641,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043531,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065003,GO:0070035,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901363 3.6.4.13 1.358e-232 726.0
HSJS2_k127_3215252_1 Domain of unknown function (DUF3520) K07114 - - 3.97e-208 667.0
HSJS2_k127_3215252_2 Protein of unknown function (DUF2914) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 419.0
HSJS2_k127_3215252_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000001045 212.0
HSJS2_k127_3215252_4 START domain - - - 0.0000000000000000000000000000000000000000000000000000000007819 211.0
HSJS2_k127_3215252_6 S4 RNA-binding domain K06183 - 5.4.99.19 0.00000000000000000000000000000009998 126.0
HSJS2_k127_3215252_7 Alpha/beta hydrolase family - - - 0.00000000000000000000000003075 115.0
HSJS2_k127_3225559_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 9.968e-262 821.0
HSJS2_k127_3225559_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 9.991e-206 644.0
HSJS2_k127_3225559_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 513.0
HSJS2_k127_3225559_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 364.0
HSJS2_k127_3225559_4 Uncharacterized protein family, UPF0114 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000003851 247.0
HSJS2_k127_3225559_5 membrane protein domain - - - 0.000000000000000000000000000000000000000000000000000000000001685 213.0
HSJS2_k127_3225559_6 Preprotein translocase subunit YajC K03210 - - 0.00000000000000000000000000000000000018 143.0
HSJS2_k127_3233809_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 5.233e-195 616.0
HSJS2_k127_3233809_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 395.0
HSJS2_k127_3233809_2 TM2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000009699 226.0
HSJS2_k127_3239116_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.677e-259 805.0
HSJS2_k127_3239116_1 COG1012 NAD-dependent aldehyde dehydrogenases K00140 - 1.2.1.18,1.2.1.27 3.307e-246 768.0
HSJS2_k127_3239116_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 558.0
HSJS2_k127_3239116_3 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006473 325.0
HSJS2_k127_3239116_4 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 288.0
HSJS2_k127_3239116_5 TetR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000004192 243.0
HSJS2_k127_3239116_6 - - - - 0.000000000000000000000000000000006455 129.0
HSJS2_k127_3247568_0 Terminase RNAseH like domain K06909 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 485.0
HSJS2_k127_3247568_1 Tfp pilus assembly protein FimV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 437.0
HSJS2_k127_3247568_10 - - - - 0.0000000000000000000000000003691 129.0
HSJS2_k127_3247568_11 ninB family - - - 0.00000000000000000000004356 104.0
HSJS2_k127_3247568_12 phosphinothricin N-acetyltransferase activity K03825,K18816 - 2.3.1.82 0.0000000000000000000002075 102.0
HSJS2_k127_3247568_13 - - - - 0.000000000000000000001118 98.0
HSJS2_k127_3247568_14 lytic transglycosylase activity K08307 - - 0.0000000000000000000134 108.0
HSJS2_k127_3247568_15 - - - - 0.000000000001003 72.0
HSJS2_k127_3247568_17 - - - - 0.0000000003898 68.0
HSJS2_k127_3247568_18 - K07483 - - 0.00000000238 63.0
HSJS2_k127_3247568_19 - - - - 0.000000006187 69.0
HSJS2_k127_3247568_2 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 354.0
HSJS2_k127_3247568_21 sequence-specific DNA binding - - - 0.0000000125 61.0
HSJS2_k127_3247568_23 TraG-like protein, N-terminal region - - - 0.0004584 47.0
HSJS2_k127_3247568_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 321.0
HSJS2_k127_3247568_4 Protein of unknown function (DUF4043) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001056 246.0
HSJS2_k127_3247568_5 Exodeoxyribonuclease VIII K10906 - - 0.0000000000000000000000000000000000000000000000000000000000001948 224.0
HSJS2_k127_3247568_6 Peptidase S24-like - - - 0.0000000000000000000000000000000000000000000000000000000004583 211.0
HSJS2_k127_3247568_7 NinG protein - - - 0.000000000000000000000000000000000000000000000000001889 189.0
HSJS2_k127_3247568_8 - - - - 0.000000000000000000000000000000000001053 147.0
HSJS2_k127_3247568_9 DnaD domain protein - - - 0.0000000000000000000000000000000000029 149.0
HSJS2_k127_3256578_0 COG3103 SH3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000181 257.0
HSJS2_k127_3256578_1 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000004703 85.0
HSJS2_k127_3256578_2 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.00000000000000008779 79.0
HSJS2_k127_3267078_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 396.0
HSJS2_k127_3267078_2 MAPEG family K07136 - - 0.000000000000000000003713 98.0
HSJS2_k127_3280971_0 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 - 6.3.1.2 2.339e-280 867.0
HSJS2_k127_3280971_1 Response regulator of a two-component regulatory system involved in the activation of nitrogen assimilation genes K07712 - - 4.753e-260 807.0
HSJS2_k127_3280971_2 Histidine kinase K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 534.0
HSJS2_k127_3280971_3 tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain - - - 0.00000000000000000000000000000000000000000003893 163.0
HSJS2_k127_3280971_4 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000002108 113.0
HSJS2_k127_3280971_5 Domain of unknown function (DUF4124) - - - 0.00000000007549 70.0
HSJS2_k127_3281013_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1182.0
HSJS2_k127_3281013_1 Converts isocitrate to alpha ketoglutarate K00031 - 1.1.1.42 4.289e-260 803.0
HSJS2_k127_3281013_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 296.0
HSJS2_k127_3281013_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000001419 253.0
HSJS2_k127_3281013_4 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000001666 235.0
HSJS2_k127_3281013_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0034214,GO:0042802,GO:0043170,GO:0043545,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0061799,GO:0065003,GO:0071704,GO:0071840,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000004474 209.0
HSJS2_k127_3281013_6 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000000000001455 176.0
HSJS2_k127_3281013_7 Cold-shock' K03704 - - 0.000000000000000000000000000002643 121.0
HSJS2_k127_3281013_8 Molybdopterin converting factor, small subunit K03636 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000003183 93.0
HSJS2_k127_329339_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0 1073.0
HSJS2_k127_329339_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 508.0
HSJS2_k127_329339_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 416.0
HSJS2_k127_329339_3 Nad-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 406.0
HSJS2_k127_329339_4 Periplasmic sensor domain found in signal transduction proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 418.0
HSJS2_k127_329339_5 Dyp-type peroxidase family K07223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 364.0
HSJS2_k127_329339_6 Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 302.0
HSJS2_k127_329339_7 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001455 204.0
HSJS2_k127_329339_8 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000004108 208.0
HSJS2_k127_3303417_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 298.0
HSJS2_k127_3303417_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000385 190.0
HSJS2_k127_3319090_0 PFAM major facilitator superfamily MFS_1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 517.0
HSJS2_k127_3319090_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007601 458.0
HSJS2_k127_3319090_10 Methyltransferase K07443 - - 0.000000000000000000000000000002699 122.0
HSJS2_k127_3319090_11 COG3678 P pilus assembly Cpx signaling pathway, periplasmic inhibitor zinc-resistance associated protein - - - 0.00000000002342 68.0
HSJS2_k127_3319090_2 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 451.0
HSJS2_k127_3319090_3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 407.0
HSJS2_k127_3319090_4 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 349.0
HSJS2_k127_3319090_5 Histidine kinase K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 324.0
HSJS2_k127_3319090_6 Transcriptional regulatory protein, C terminal K07664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001535 248.0
HSJS2_k127_3319090_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000373 193.0
HSJS2_k127_3319090_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000008414 162.0
HSJS2_k127_3319090_9 Heme iron utilization protein - - - 0.00000000000000000000000000000000000000004598 160.0
HSJS2_k127_3326924_0 May be involved in recombinational repair of damaged DNA K03631 - - 7.832e-229 725.0
HSJS2_k127_3326924_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 511.0
HSJS2_k127_3326924_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000005822 223.0
HSJS2_k127_3326924_3 belongs to the Fur family K03711 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032991,GO:0032993,GO:0043167,GO:0043169,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000002665 64.0
HSJS2_k127_3327383_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 411.0
HSJS2_k127_3327383_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 314.0
HSJS2_k127_3327383_2 Belongs to the UPF0246 family K09861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005048 247.0
HSJS2_k127_3327475_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 621.0
HSJS2_k127_3327475_1 AMP-binding enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 302.0
HSJS2_k127_3327475_2 COG0489 ATPases involved in chromosome partitioning - - - 0.000000000000000000000000000000000000000000002363 174.0
HSJS2_k127_3327475_3 Phosphopantetheine attachment site - - - 0.0000000000000000000001006 99.0
HSJS2_k127_3327475_4 Putative beta-barrel porin 2 - - - 0.000000002025 70.0
HSJS2_k127_3327475_5 protein involved in exopolysaccharide biosynthesis - - - 0.00001435 50.0
HSJS2_k127_3334_0 2-Keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 348.0
HSJS2_k127_3339441_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1192.0
HSJS2_k127_3339441_1 Fe-S oxidoreductases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 465.0
HSJS2_k127_3339441_2 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000000000000002299 226.0
HSJS2_k127_3339441_3 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000406 213.0
HSJS2_k127_3339441_4 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000002206 206.0
HSJS2_k127_3339441_5 protein conserved in bacteria K09931 - - 0.00000000000000000000000000000000006985 142.0
HSJS2_k127_3339441_6 FOG HPt domain K20976 - - 0.00000000000000001726 86.0
HSJS2_k127_3339441_8 OmpA-like transmembrane domain - - - 0.0006148 46.0
HSJS2_k127_3345960_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 2.745e-228 721.0
HSJS2_k127_3345960_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003623 264.0
HSJS2_k127_3351528_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K20455 - 4.2.1.117 2.604e-281 867.0
HSJS2_k127_3360393_0 SAM-dependent K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 512.0
HSJS2_k127_3360393_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 480.0
HSJS2_k127_3360393_2 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 377.0
HSJS2_k127_3360393_3 biosynthesis protein HemY K02498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 363.0
HSJS2_k127_3360393_4 enzyme of heme biosynthesis K02496 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000003886 257.0
HSJS2_k127_3360393_5 synthase K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000000000000000001272 217.0
HSJS2_k127_3364235_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 434.0
HSJS2_k127_3364235_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 414.0
HSJS2_k127_3364235_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 366.0
HSJS2_k127_3364235_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 356.0
HSJS2_k127_3364235_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07032 - - 0.0000000000000000000000000000000000000000000000000000000001567 211.0
HSJS2_k127_3365993_0 Glycerol-3-phosphate dehydrogenase K00111,K21054 - 1.1.1.402,1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 500.0
HSJS2_k127_3365993_1 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00004754 45.0
HSJS2_k127_3387409_0 - - - - 9.726e-220 692.0
HSJS2_k127_3387409_1 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 489.0
HSJS2_k127_3387409_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 361.0
HSJS2_k127_3387409_3 diguanylate cyclase K11444 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000005114 278.0
HSJS2_k127_3387409_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005814 225.0
HSJS2_k127_3387409_5 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.000000000000000000000000000000000000000000000000000000002218 200.0
HSJS2_k127_3387409_6 dihydroorotase K01465 - 3.5.2.3 0.000000000001364 68.0
HSJS2_k127_3396777_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 468.0
HSJS2_k127_3396777_1 COG0543 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 387.0
HSJS2_k127_3396777_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 316.0
HSJS2_k127_3396777_3 RHS Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003287 269.0
HSJS2_k127_3396777_4 Methyltransferase type 12 - - - 0.0000000000000000000000000000000000000000000000000009622 194.0
HSJS2_k127_3396911_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004809 623.0
HSJS2_k127_3396911_1 Small-conductance mechanosensitive channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 391.0
HSJS2_k127_3396911_2 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000002587 156.0
HSJS2_k127_3404266_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 2.585e-223 702.0
HSJS2_k127_3404266_1 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 420.0
HSJS2_k127_3404266_2 Belongs to the UPF0149 family K09895 - - 0.00000000000000000000000000000000000000000000008413 175.0
HSJS2_k127_3404266_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.000000000000000000000000000000000000000000004708 171.0
HSJS2_k127_3404266_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000003712 117.0
HSJS2_k127_3404266_5 TIGRFAM TIGR02449 family protein K09892 - - 0.0000000000000000001617 91.0
HSJS2_k127_3405823_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 456.0
HSJS2_k127_3405823_1 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.000000000000000000000000000000004431 130.0
HSJS2_k127_3411829_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.705e-287 892.0
HSJS2_k127_3411829_1 acyl-CoA dehydrogenase K09456 - - 1.701e-267 833.0
HSJS2_k127_3411829_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 596.0
HSJS2_k127_3411829_3 COG1192 ATPases involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 387.0
HSJS2_k127_3411829_4 Domain of unknown function (DUF4062) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 361.0
HSJS2_k127_3411829_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003769 275.0
HSJS2_k127_3411829_6 Histidine kinase K07717,K15011 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003263 276.0
HSJS2_k127_3411829_7 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain K15012 - - 0.00000000000000000000000000000000000000000000000000000001114 203.0
HSJS2_k127_3411829_8 protein, possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000007121 185.0
HSJS2_k127_3436534_0 Deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 5.534e-238 741.0
HSJS2_k127_3436534_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 360.0
HSJS2_k127_3436534_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 325.0
HSJS2_k127_3436534_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000007216 241.0
HSJS2_k127_3436534_4 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000003596 227.0
HSJS2_k127_3436534_5 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000000000000000000004472 199.0
HSJS2_k127_3436534_6 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.000000000000000000000000000000000000000000006376 168.0
HSJS2_k127_3454171_0 Cysteine desulfurase activator complex subunit SufB K09014 - - 5.465e-287 884.0
HSJS2_k127_3454171_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 614.0
HSJS2_k127_3454171_2 ABC-type transport system involved in Fe-S cluster assembly, ATPase component K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 414.0
HSJS2_k127_3454171_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001576 249.0
HSJS2_k127_3454171_4 COG3063 Tfp pilus assembly protein PilF K02656 - - 0.0000000000000000000002405 99.0
HSJS2_k127_3454171_5 COG0719 ABC-type transport system involved in Fe-S cluster assembly, permease component K09015 - - 0.00000008932 59.0
HSJS2_k127_3457750_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.249e-231 734.0
HSJS2_k127_3457750_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000002016 110.0
HSJS2_k127_3479908_0 recombinase XerD K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 448.0
HSJS2_k127_3479908_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000006841 231.0
HSJS2_k127_3479908_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000001132 212.0
HSJS2_k127_3484131_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1729.0
HSJS2_k127_3484131_1 kinase activity K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 491.0
HSJS2_k127_3484131_2 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 385.0
HSJS2_k127_3484131_3 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 378.0
HSJS2_k127_3484131_4 Protein of unknown function (DUF1461) - - - 0.00000000000000000000000000000000000000000000000000000000000019 222.0
HSJS2_k127_3489737_0 Adenylyltransferase that mediates the addition of adenosine 5'-monophosphate (AMP) to specific residues of target proteins - GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006464,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018117,GO:0018175,GO:0019538,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046872,GO:0046983,GO:0070566,GO:0070733,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564 - 2.669e-210 657.0
HSJS2_k127_3489737_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004082 419.0
HSJS2_k127_3489737_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 303.0
HSJS2_k127_3489737_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000002416 241.0
HSJS2_k127_3489737_4 DNA helicase - - - 0.0000000000000000000000000000000000000002165 152.0
HSJS2_k127_3489737_5 PFAM helix-turn-helix domain protein - - - 0.0004391 44.0
HSJS2_k127_349076_0 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 460.0
HSJS2_k127_349076_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005857 447.0
HSJS2_k127_349076_3 Chromosome partitioning K03496 - - 0.000000000001437 67.0
HSJS2_k127_3498644_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 511.0
HSJS2_k127_3498644_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 350.0
HSJS2_k127_3498644_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000002016 252.0
HSJS2_k127_3498644_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000003947 138.0
HSJS2_k127_3508257_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1035.0
HSJS2_k127_3508257_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 576.0
HSJS2_k127_3508257_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 340.0
HSJS2_k127_3508257_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0001086 45.0
HSJS2_k127_3527246_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 2.072e-258 811.0
HSJS2_k127_3527246_1 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 318.0
HSJS2_k127_3527246_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000006733 200.0
HSJS2_k127_3527246_3 GDYXXLXY protein - - - 0.0000000000000000000000000000001759 131.0
HSJS2_k127_3527246_4 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.000000000001598 69.0
HSJS2_k127_3542017_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 545.0
HSJS2_k127_3542017_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 503.0
HSJS2_k127_3548147_0 COG2909 ATP-dependent transcriptional regulator - - - 0.0 1382.0
HSJS2_k127_3585791_0 Sodium:dicarboxylate symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 535.0
HSJS2_k127_3585791_1 Alpha beta hydrolase K01046 GO:0003674,GO:0003824,GO:0004806,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0052689,GO:0071704,GO:1901575 3.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 525.0
HSJS2_k127_3585791_2 May be involved in the folding of the extracellular lipase during its passage through the periplasm - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 347.0
HSJS2_k127_3585791_3 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000738 335.0
HSJS2_k127_3585791_4 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 312.0
HSJS2_k127_3585791_5 - - - - 0.0002061 44.0
HSJS2_k127_3587366_0 - - - - 3.215e-243 767.0
HSJS2_k127_3587366_1 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 3.998e-203 638.0
HSJS2_k127_3587366_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 244.0
HSJS2_k127_3591169_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 562.0
HSJS2_k127_3591169_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 299.0
HSJS2_k127_3591169_2 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.00000000000000000000000000000000000000000000000000000001445 205.0
HSJS2_k127_3591169_3 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000001019 173.0
HSJS2_k127_360663_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12136 - - 1.282e-289 909.0
HSJS2_k127_360663_1 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 334.0
HSJS2_k127_360663_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009067 275.0
HSJS2_k127_3611704_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000002622 242.0
HSJS2_k127_3611704_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.2.1.11 0.000000000000000000000000000000000000002014 160.0
HSJS2_k127_3611704_2 Tfp pilus assembly protein K08086 - - 0.00000000000000000000000004471 110.0
HSJS2_k127_3618239_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 6.059e-229 713.0
HSJS2_k127_3618239_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 6.297e-219 687.0
HSJS2_k127_3618239_10 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000005371 227.0
HSJS2_k127_3618239_11 Protein of unknown function (DUF1304) K08987 - - 0.00000000000000000000000000000000000000000000003555 171.0
HSJS2_k127_3618239_12 amino acid transport K02030 - - 0.000000000000000000000000000000000000002548 156.0
HSJS2_k127_3618239_13 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.000000000000000000000000000000000000019 145.0
HSJS2_k127_3618239_14 Membrane - - - 0.00000000000000000000000000000000000009536 145.0
HSJS2_k127_3618239_15 Predicted membrane protein (DUF2214) K08983 - - 0.00000000000000000000000000000000002157 139.0
HSJS2_k127_3618239_16 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03972 GO:0003674,GO:0003824,GO:0004792,GO:0005575,GO:0005623,GO:0016740,GO:0016782,GO:0016783,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.000000000000000000000000000003555 124.0
HSJS2_k127_3618239_17 Belongs to the UPF0250 family K09158 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000001278 116.0
HSJS2_k127_3618239_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 516.0
HSJS2_k127_3618239_3 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 414.0
HSJS2_k127_3618239_4 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 382.0
HSJS2_k127_3618239_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 315.0
HSJS2_k127_3618239_6 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 314.0
HSJS2_k127_3618239_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007696 282.0
HSJS2_k127_3618239_8 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001449 250.0
HSJS2_k127_3618239_9 OmpA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003939 259.0
HSJS2_k127_3630783_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 295.0
HSJS2_k127_3630783_1 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000000000000000000004291 246.0
HSJS2_k127_3630783_2 Domain of unknown function (DUF4259) - - - 0.0000000000000000000000000000000000000000000000000001223 188.0
HSJS2_k127_3630783_3 Domain of unknown function (DUF4166) - - - 0.0000000000000000000000000000000159 133.0
HSJS2_k127_3644307_1 Protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000000000005335 196.0
HSJS2_k127_3644307_2 Protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000000546 170.0
HSJS2_k127_3644307_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000696 127.0
HSJS2_k127_3644307_4 Domain of unknown function (DUF4034) - - - 0.000000000000008174 86.0
HSJS2_k127_3647177_0 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 352.0
HSJS2_k127_3647177_1 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 350.0
HSJS2_k127_3647177_2 Protein of unknown function (DUF1275) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002064 271.0
HSJS2_k127_3651876_0 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004931 605.0
HSJS2_k127_3651876_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 541.0
HSJS2_k127_3662792_0 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 552.0
HSJS2_k127_3662792_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006552 275.0
HSJS2_k127_3662792_2 - - - - 0.0000000000000000000000000000000000000000000000000000001771 202.0
HSJS2_k127_3722707_0 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 3.273e-196 616.0
HSJS2_k127_3722707_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 490.0
HSJS2_k127_3722707_2 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 419.0
HSJS2_k127_3722707_3 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 354.0
HSJS2_k127_3722707_4 Belongs to the UPF0260 family K09160 - - 0.000000000000000000000000000000000000000000000000000007948 193.0
HSJS2_k127_3722707_5 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.000000000000000000000000000000000000000000000002605 177.0
HSJS2_k127_3722707_6 YcgL domain-containing protein K09902 - - 0.000000000000000002641 88.0
HSJS2_k127_3722707_8 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000005825 64.0
HSJS2_k127_3728156_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 2.2e-250 780.0
HSJS2_k127_3728156_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 456.0
HSJS2_k127_3728156_2 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000007542 251.0
HSJS2_k127_3728156_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000002493 52.0
HSJS2_k127_3728636_0 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 319.0
HSJS2_k127_3728636_1 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001247 291.0
HSJS2_k127_3728636_2 Pfam:DUF46 - - - 0.00000000000000000000000000000000000000000001248 168.0
HSJS2_k127_3728636_3 TIGRFAM YD repeat protein - - - 0.00000000000007797 73.0
HSJS2_k127_3731532_0 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 393.0
HSJS2_k127_3731532_1 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 317.0
HSJS2_k127_3731532_2 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000001107 116.0
HSJS2_k127_3731532_3 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.0006046 44.0
HSJS2_k127_3731609_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1097.0
HSJS2_k127_3731609_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 421.0
HSJS2_k127_3731609_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 295.0
HSJS2_k127_3742450_0 in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor K14260 - 2.6.1.2,2.6.1.66 1.012e-226 706.0
HSJS2_k127_3742450_1 ATP-NAD kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 479.0
HSJS2_k127_3742450_2 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 357.0
HSJS2_k127_3742450_3 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 355.0
HSJS2_k127_3742450_4 3-methyladenine DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 324.0
HSJS2_k127_3742450_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000007568 223.0
HSJS2_k127_3742450_6 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000001182 225.0
HSJS2_k127_3742450_7 - - - - 0.000000000000000000000000000000000000000000000008204 177.0
HSJS2_k127_3744116_0 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 302.0
HSJS2_k127_3744116_1 Positive regulator of K03803 - - 0.00000000000000000000000000000005926 129.0
HSJS2_k127_3744116_2 Negative regulator of sigma E activity K03598 - - 0.00000000000000001797 85.0
HSJS2_k127_3754653_0 belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 2.505e-214 674.0
HSJS2_k127_3754653_1 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 556.0
HSJS2_k127_3754653_2 Peptidase, M16 K00960,K07263 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 522.0
HSJS2_k127_3754653_3 GMC oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 363.0
HSJS2_k127_3754653_4 hydrolase of the alpha beta-hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 293.0
HSJS2_k127_3754653_5 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008234 281.0
HSJS2_k127_3754653_6 Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000006987 239.0
HSJS2_k127_3754653_7 - - - - 0.0000000000000000000000000000000000000005166 154.0
HSJS2_k127_3756707_0 chitin binding K21712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 585.0
HSJS2_k127_3756707_1 dienelactone hydrolase K21104 - 3.1.1.101 0.00000000000000000000000000000000009573 136.0
HSJS2_k127_3758776_0 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 387.0
HSJS2_k127_3758776_1 protein conserved in bacteria K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007024 290.0
HSJS2_k127_3758776_2 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001324 267.0
HSJS2_k127_3758776_3 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.00000000000000000000000000000000000000000000009261 171.0
HSJS2_k127_3758776_4 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000003827 120.0
HSJS2_k127_3758776_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000001393 89.0
HSJS2_k127_3764900_0 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 352.0
HSJS2_k127_3764900_1 flavoprotein involved in K transport K03379 - 1.14.13.22 0.000000000000000000000000000000000000000000009564 164.0
HSJS2_k127_377145_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034645,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 1.426e-302 953.0
HSJS2_k127_377145_1 Participates in both transcription termination and antitermination K02600 - - 2.707e-262 814.0
HSJS2_k127_377145_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004464 421.0
HSJS2_k127_377145_3 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002461 250.0
HSJS2_k127_377145_4 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000816 215.0
HSJS2_k127_377145_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000000001148 195.0
HSJS2_k127_377145_6 Preprotein translocase K03075 - - 0.0000000000000000000000000000000000001088 145.0
HSJS2_k127_377145_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000001125 140.0
HSJS2_k127_377145_8 - - - - 0.0000000007165 60.0
HSJS2_k127_3772466_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 5.48e-208 652.0
HSJS2_k127_3772466_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 361.0
HSJS2_k127_3772466_2 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000003163 239.0
HSJS2_k127_3772466_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000000000000008109 170.0
HSJS2_k127_3776304_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) K01563 - 3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 299.0
HSJS2_k127_3776304_1 COG1309 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000008126 227.0
HSJS2_k127_3776304_2 Transcriptional regulator K16137 - - 0.00000000000000000000000002494 115.0
HSJS2_k127_3776304_3 acyl-CoA dehydrogenase K09456 - - 0.0000000000000000002394 91.0
HSJS2_k127_3779439_0 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 496.0
HSJS2_k127_3779439_1 Late embryogenesis abundant protein - - - 0.0000000000000000000000000003854 119.0
HSJS2_k127_3779439_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000005511 60.0
HSJS2_k127_378090_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 2.271e-315 987.0
HSJS2_k127_378090_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 328.0
HSJS2_k127_378090_2 Thioredoxin K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000001608 181.0
HSJS2_k127_378097_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 3.732e-249 774.0
HSJS2_k127_378097_1 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 4.59e-197 634.0
HSJS2_k127_378097_10 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000003131 205.0
HSJS2_k127_378097_11 Thioredoxin - - - 0.000000000000000000000000000000000000000000004948 168.0
HSJS2_k127_378097_12 Domain of unknown function (DUF4266) - - - 0.00000000000000000000000002484 109.0
HSJS2_k127_378097_2 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 488.0
HSJS2_k127_378097_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 477.0
HSJS2_k127_378097_4 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 364.0
HSJS2_k127_378097_5 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008941 351.0
HSJS2_k127_378097_6 Protein of unknown function (DUF3426) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004075 304.0
HSJS2_k127_378097_7 Histidine kinase K02484,K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 301.0
HSJS2_k127_378097_8 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000002327 234.0
HSJS2_k127_378097_9 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000573 225.0
HSJS2_k127_3785428_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0 1105.0
HSJS2_k127_3785428_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003533 263.0
HSJS2_k127_3785428_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006293 243.0
HSJS2_k127_3797595_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 507.0
HSJS2_k127_3797595_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 449.0
HSJS2_k127_3797595_2 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003855 280.0
HSJS2_k127_3797595_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000375 270.0
HSJS2_k127_3797595_4 COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004393 249.0
HSJS2_k127_3797595_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000003332 251.0
HSJS2_k127_3797595_6 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000000000000127 204.0
HSJS2_k127_3797595_7 Domain of unknown function (DUF4124) - - - 0.000000000000000001211 93.0
HSJS2_k127_379871_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.588e-291 900.0
HSJS2_k127_379871_1 DNA polymerase K02337 - 2.7.7.7 7.579e-212 667.0
HSJS2_k127_379871_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 546.0
HSJS2_k127_379871_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 338.0
HSJS2_k127_379871_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000004336 276.0
HSJS2_k127_380443_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.8e-254 794.0
HSJS2_k127_380443_1 Mobile mystery protein B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 310.0
HSJS2_k127_380443_2 Mobile mystery protein A - - - 0.000000000000000000000000000000000000000002909 160.0
HSJS2_k127_380443_3 Protein of unknown function (DUF2834) - - - 0.000000000000000000000000000000000001629 143.0
HSJS2_k127_380443_4 Cytochrome c K12263 - - 0.000000000000000000000000008251 115.0
HSJS2_k127_380443_5 Antirestriction protein (ArdA) - - - 0.00000000001548 65.0
HSJS2_k127_3806937_0 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 2.738e-206 648.0
HSJS2_k127_3806937_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 512.0
HSJS2_k127_3806937_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.0000000000000000000000000000000000001437 145.0
HSJS2_k127_3807018_0 Amidase K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 539.0
HSJS2_k127_3807018_1 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 443.0
HSJS2_k127_3807018_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 299.0
HSJS2_k127_3807018_3 GXWXG protein - - - 0.0000000000000000000000000000000000000000000000000000000001496 208.0
HSJS2_k127_3807018_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000003307 169.0
HSJS2_k127_3807018_5 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000001563 155.0
HSJS2_k127_3807018_6 Cold shock protein domain K03704 - - 0.00000000000000000000000000000000009748 133.0
HSJS2_k127_3807018_7 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.0000000000000000000000000000007205 123.0
HSJS2_k127_3810312_0 COG0457 FOG TPR repeat - - - 0.0 1245.0
HSJS2_k127_3810312_1 Tetratricopeptide repeat - - - 3.901e-250 786.0
HSJS2_k127_3810312_2 - - - - 0.000000000000000000000000000000000000000000000000000002238 195.0
HSJS2_k127_3810312_3 PFAM Integrase, catalytic region K07497 - - 0.00000000000002978 73.0
HSJS2_k127_382331_0 TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 496.0
HSJS2_k127_382331_1 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 294.0
HSJS2_k127_3838166_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1596.0
HSJS2_k127_3838166_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 8.868e-197 624.0
HSJS2_k127_3838166_2 permease K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 492.0
HSJS2_k127_3838166_3 Permease K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 437.0
HSJS2_k127_3838166_4 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 352.0
HSJS2_k127_3838166_5 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K11890,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000003716 227.0
HSJS2_k127_3838166_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000003139 215.0
HSJS2_k127_3838166_7 DNA polymerase III chi subunit K02339 - 2.7.7.7 0.0000000000000000000000000000000000004925 149.0
HSJS2_k127_3840251_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005984 335.0
HSJS2_k127_3840251_1 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000003631 173.0
HSJS2_k127_3854080_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 2.624e-240 753.0
HSJS2_k127_3854080_1 protein conserved in bacteria K09919 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 426.0
HSJS2_k127_3854080_2 COG0501 Zn-dependent protease with chaperone function - - - 0.000000000000000000000000000000000000000000000000000000000002631 219.0
HSJS2_k127_3854080_3 Cold-shock' K03704 - - 0.00000000000000000000000000000000000000000000000000006361 195.0
HSJS2_k127_3854080_5 - - - - 0.0002274 44.0
HSJS2_k127_3863087_0 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 536.0
HSJS2_k127_3863087_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 400.0
HSJS2_k127_3863087_2 - - - - 0.00000000000000000000195 102.0
HSJS2_k127_3863087_3 Bacterial regulatory proteins, tetR family - - - 0.000001492 58.0
HSJS2_k127_386699_0 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 486.0
HSJS2_k127_386699_1 haloacid K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 440.0
HSJS2_k127_386699_2 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 414.0
HSJS2_k127_386699_3 PhnA protein K06193 - - 0.000000000000000000000000000000000000000000000000000000000000000000003027 239.0
HSJS2_k127_386699_4 - - - - 0.00000000000000000000007866 103.0
HSJS2_k127_3872985_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 579.0
HSJS2_k127_3872985_1 Functions as both a chaperone and a metalloprotease. Maintains the integrity of the outer membrane by promoting either the assembly or the elimination of outer membrane proteins, depending on their folding state - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 490.0
HSJS2_k127_3872985_10 YHYH protein - - - 0.000000000000000000000000000000000000000000000000006764 195.0
HSJS2_k127_3872985_11 - - - - 0.0000000000000000000008686 96.0
HSJS2_k127_3872985_12 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000007915 85.0
HSJS2_k127_3872985_13 - - - - 0.00006128 51.0
HSJS2_k127_3872985_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 475.0
HSJS2_k127_3872985_3 Permease K03548 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 460.0
HSJS2_k127_3872985_4 Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 406.0
HSJS2_k127_3872985_5 beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 364.0
HSJS2_k127_3872985_6 glycine cleavage system K03567 - - 0.000000000000000000000000000000000000000000000000000000000000000000000749 240.0
HSJS2_k127_3872985_7 Peroxiredoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000002583 231.0
HSJS2_k127_3872985_8 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000004372 224.0
HSJS2_k127_3872985_9 NlpB/DapX lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000002287 203.0
HSJS2_k127_3873882_0 Bacterial Ig-like domain - - - 2.195e-247 799.0
HSJS2_k127_3873882_1 Bacterial Ig-like domain - - - 3.323e-221 723.0
HSJS2_k127_3873882_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 1.438e-220 692.0
HSJS2_k127_3873882_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 533.0
HSJS2_k127_3873882_4 COG2067 Long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 536.0
HSJS2_k127_3873882_5 COG2067 Long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 517.0
HSJS2_k127_3873882_6 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 482.0
HSJS2_k127_3873882_7 hydroxylase K18800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 342.0
HSJS2_k127_3873882_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 GO:0001505,GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0017144,GO:0019464,GO:0019752,GO:0031405,GO:0031406,GO:0033293,GO:0036094,GO:0042133,GO:0042135,GO:0042737,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901681 - 0.0000000000000000000000000000000000000000000000000000001609 196.0
HSJS2_k127_3881172_0 GH3 auxin-responsive promoter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 557.0
HSJS2_k127_3881172_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 332.0
HSJS2_k127_3881172_2 - - - - 0.000000000000000000000000000000007266 132.0
HSJS2_k127_3881172_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000001384 72.0
HSJS2_k127_3898087_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1111.0
HSJS2_k127_3898087_1 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 6.601e-211 664.0
HSJS2_k127_3898087_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004804 246.0
HSJS2_k127_3901363_0 COG1943 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000005408 239.0
HSJS2_k127_3901363_1 Protein of unknown function (DUF2986) - - - 0.00000001633 57.0
HSJS2_k127_3933533_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.853e-303 934.0
HSJS2_k127_3933533_1 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.123e-278 863.0
HSJS2_k127_3933533_10 Cbb3-type cytochrome oxidase component FixQ K00407 - - 0.000000000000004191 76.0
HSJS2_k127_3933533_11 Cytochrome oxidase maturation protein - - - 0.000000007917 63.0
HSJS2_k127_3933533_2 COG2217 Cation transport ATPase K01533 - 3.6.3.4 2.847e-210 683.0
HSJS2_k127_3933533_3 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 331.0
HSJS2_k127_3933533_4 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 327.0
HSJS2_k127_3933533_5 XRE family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001386 249.0
HSJS2_k127_3933533_6 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000002815 196.0
HSJS2_k127_3933533_7 Regulatory protein LuxR - - - 0.00000000000000000000000000000000000000000000000009282 192.0
HSJS2_k127_3933533_8 DoxX K15977 - - 0.000000000000000000000000000000000000000000000005634 176.0
HSJS2_k127_3933533_9 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.000000000000000000000000000000007548 127.0
HSJS2_k127_3934875_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005552 424.0
HSJS2_k127_3934875_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000001805 207.0
HSJS2_k127_3934875_2 DNA-binding protein VF530 - GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000006951 124.0
HSJS2_k127_3935388_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 403.0
HSJS2_k127_3935388_1 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000844 184.0
HSJS2_k127_3935388_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000003404 167.0
HSJS2_k127_3935388_3 TIGRFAM Hydrolase, ortholog 1, exosortase system type 1 associated - - - 0.0000000000000000000000000000001917 136.0
HSJS2_k127_3935388_4 lipopolysaccharide biosynthesis protein - - - 0.0000000000000000000000000000959 127.0
HSJS2_k127_3935388_5 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000001013 64.0
HSJS2_k127_3935388_6 Serine aminopeptidase, S33 - - - 0.000000000113 72.0
HSJS2_k127_3938012_0 ABC transporter ATP-binding protein K06158 - - 5.895e-238 752.0
HSJS2_k127_3938012_1 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 619.0
HSJS2_k127_3938012_10 effector of murein hydrolase - - - 0.0000000001397 64.0
HSJS2_k127_3938012_2 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008841 279.0
HSJS2_k127_3938012_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004112 258.0
HSJS2_k127_3938012_4 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000006213 201.0
HSJS2_k127_3938012_5 effector of murein hydrolase - - - 0.000000000000000000000000000000000000000000000000000001706 196.0
HSJS2_k127_3938012_6 Belongs to the Rsd AlgQ family K07740 - - 0.000000000000000000000000000000000000000000000006954 177.0
HSJS2_k127_3938012_7 Protein of unknown function (DUF2390) - - - 0.00000000000000000000000000057 119.0
HSJS2_k127_3939442_0 Sterol-sensing domain of SREBP cleavage-activation K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009643 481.0
HSJS2_k127_3939442_1 endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002732 302.0
HSJS2_k127_3939442_2 D-alanine [D-alanyl carrier protein] ligase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000198 235.0
HSJS2_k127_3940346_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 567.0
HSJS2_k127_3940346_1 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 464.0
HSJS2_k127_3940346_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000065 406.0
HSJS2_k127_3940346_3 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 374.0
HSJS2_k127_3940346_4 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 293.0
HSJS2_k127_3940346_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000007304 240.0
HSJS2_k127_3940346_6 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000000000274 94.0
HSJS2_k127_3948469_0 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000003119 266.0
HSJS2_k127_3948469_1 phosphatidylcholine synthase activity K01004,K17103 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006629,GO:0006644,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0019637,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0050520,GO:0071704,GO:0090407,GO:1901576 2.7.8.24,2.7.8.8 0.000000000000000000000000000000000000000000000006212 179.0
HSJS2_k127_3948469_2 Pfam:DUF46 - - - 0.0000439 46.0
HSJS2_k127_3955719_0 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 477.0
HSJS2_k127_3955719_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000002517 246.0
HSJS2_k127_3955719_2 protein conserved in bacteria K05952 - - 0.00000000000000000004592 94.0
HSJS2_k127_3963964_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006617 552.0
HSJS2_k127_3963964_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000001034 114.0
HSJS2_k127_3967957_0 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 473.0
HSJS2_k127_3967957_1 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000144 175.0
HSJS2_k127_3967957_2 Protein of unknown function (DUF1272) K09984 - - 0.0000000000000000000000000000000000000295 143.0
HSJS2_k127_3969567_0 membrane - - - 2.14e-269 875.0
HSJS2_k127_3969567_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.029e-248 774.0
HSJS2_k127_3969567_10 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000004599 184.0
HSJS2_k127_3969567_11 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.00000000000000000000000000000000000000000000003244 174.0
HSJS2_k127_3969567_12 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000195 153.0
HSJS2_k127_3969567_13 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000002358 126.0
HSJS2_k127_3969567_14 - - - - 0.000000000000000006061 88.0
HSJS2_k127_3969567_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.167e-245 763.0
HSJS2_k127_3969567_3 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 7.633e-235 734.0
HSJS2_k127_3969567_4 Rod shape-determining protein K03569 - - 2.962e-201 630.0
HSJS2_k127_3969567_5 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009708 530.0
HSJS2_k127_3969567_6 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 346.0
HSJS2_k127_3969567_7 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 344.0
HSJS2_k127_3969567_8 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000006545 265.0
HSJS2_k127_3969567_9 Carbon-nitrogen hydrolase K01501,K11206 - 3.5.5.1 0.000000000000000000000000000000000000000000000000002632 193.0
HSJS2_k127_3975779_0 NAD FAD-binding protein K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 526.0
HSJS2_k127_3975779_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 324.0
HSJS2_k127_3975779_2 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003108 247.0
HSJS2_k127_3975779_3 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000003612 205.0
HSJS2_k127_3975779_4 DNA photolyase K01669 GO:0000003,GO:0000166,GO:0000719,GO:0001101,GO:0002252,GO:0002376,GO:0003006,GO:0003674,GO:0003824,GO:0003904,GO:0003913,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005773,GO:0006139,GO:0006259,GO:0006281,GO:0006290,GO:0006325,GO:0006338,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006873,GO:0006874,GO:0006875,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0007154,GO:0007165,GO:0007275,GO:0007623,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009314,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009606,GO:0009607,GO:0009615,GO:0009628,GO:0009637,GO:0009638,GO:0009642,GO:0009645,GO:0009646,GO:0009648,GO:0009719,GO:0009725,GO:0009785,GO:0009791,GO:0009881,GO:0009882,GO:0009888,GO:0009893,GO:0009909,GO:0009911,GO:0009987,GO:0010033,GO:0010035,GO:0010073,GO:0010075,GO:0010118,GO:0010228,GO:0010244,GO:0010617,GO:0014070,GO:0016043,GO:0016604,GO:0016829,GO:0016830,GO:0017076,GO:0019222,GO:0019637,GO:0019725,GO:0022414,GO:0022603,GO:0023052,GO:0030003,GO:0030522,GO:0030554,GO:0031323,GO:0031325,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0033993,GO:0034641,GO:0035639,GO:0036094,GO:0038023,GO:0040008,GO:0042221,GO:0042592,GO:0042726,GO:0042752,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0048037,GO:0048507,GO:0048509,GO:0048511,GO:0048518,GO:0048522,GO:0048571,GO:0048573,GO:0048574,GO:0048580,GO:0048582,GO:0048583,GO:0048608,GO:0048638,GO:0048731,GO:0048831,GO:0048856,GO:0048878,GO:0050660,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050896,GO:0051094,GO:0051186,GO:0051239,GO:0051240,GO:0051276,GO:0051480,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055086,GO:0060089,GO:0061458,GO:0065007,GO:0065008,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071483,GO:0071704,GO:0071840,GO:0071949,GO:0072387,GO:0072503,GO:0072507,GO:0090304,GO:0097159,GO:0097367,GO:0098542,GO:0098771,GO:0104004,GO:0140097,GO:1900618,GO:1901265,GO:1901360,GO:1901363,GO:1901371,GO:1901564,GO:1901700,GO:1902347,GO:1905421,GO:2000024,GO:2000026,GO:2000028,GO:2000241,GO:2000243,GO:2000377,GO:2000379 4.1.99.3 0.00000000000000000005475 92.0
HSJS2_k127_3979450_0 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 375.0
HSJS2_k127_3979450_1 Serine aminopeptidase, S33 - - - 0.000000000001156 71.0
HSJS2_k127_398325_0 Belongs to the citrate synthase family K01659 GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.5 4.888e-211 660.0
HSJS2_k127_398325_1 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 511.0
HSJS2_k127_3995571_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 6.907e-238 743.0
HSJS2_k127_3995571_1 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 9.306e-212 681.0
HSJS2_k127_3995571_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 610.0
HSJS2_k127_3995571_3 Uncharacterised signal transduction histidine kinase domain (DUF2222) K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 597.0
HSJS2_k127_3995571_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 484.0
HSJS2_k127_3995571_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 424.0
HSJS2_k127_3995571_6 transport system, periplasmic component - - - 0.00000000000000000002095 102.0
HSJS2_k127_3995571_7 protein conserved in bacteria - GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031233,GO:0044425,GO:0044459,GO:0044464,GO:0071575,GO:0071944,GO:0098552 - 0.0000001318 55.0
HSJS2_k127_4007710_0 Cytochrome bd-type quinol oxidase, subunit 1 K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 521.0
HSJS2_k127_4007710_1 TIGRFAM cytochrome d ubiquinol oxidase, subunit II K00426 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 349.0
HSJS2_k127_4007710_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000001428 173.0
HSJS2_k127_4026039_0 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 440.0
HSJS2_k127_4026039_1 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 290.0
HSJS2_k127_4026039_2 Sulfur carrier protein TusA K04085 - - 0.000000000000000000000000000008694 122.0
HSJS2_k127_4026039_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000002804 113.0
HSJS2_k127_403117_0 Neutral/alkaline non-lysosomal ceramidase, N-terminal K12349 - 3.5.1.23 2.772e-228 726.0
HSJS2_k127_403117_1 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 6.893e-204 639.0
HSJS2_k127_403117_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000005659 262.0
HSJS2_k127_403117_3 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001189 246.0
HSJS2_k127_403117_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 0.0000000000000000000000000000000000001949 147.0
HSJS2_k127_403117_6 - - - - 0.000000000000000000000000000005415 128.0
HSJS2_k127_403117_7 AAA domain - - - 0.00001366 57.0
HSJS2_k127_4031599_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1046.0
HSJS2_k127_4031599_1 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1014.0
HSJS2_k127_4031599_12 - - - - 0.00009728 45.0
HSJS2_k127_4031599_2 Aminotransferase K00812 - 2.6.1.1 7.106e-202 634.0
HSJS2_k127_4031599_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 568.0
HSJS2_k127_4031599_4 Arm DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 460.0
HSJS2_k127_4031599_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001242 270.0
HSJS2_k127_4031599_6 Transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000104 220.0
HSJS2_k127_4031599_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000002702 198.0
HSJS2_k127_4031599_8 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000000000000000006008 153.0
HSJS2_k127_4031599_9 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000000003248 109.0
HSJS2_k127_4042865_0 Protein of unknown function (DUF1329) - - - 4.348e-241 751.0
HSJS2_k127_4042865_1 Protein of unknown function (DUF1302) - - - 0.000000000000000000000000000000000000000000000000002044 183.0
HSJS2_k127_4042865_2 COG1073 Hydrolases of the alpha beta superfamily - - - 0.00000006482 59.0
HSJS2_k127_4061079_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K13776 - - 3e-323 998.0
HSJS2_k127_4061079_1 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 9.617e-276 863.0
HSJS2_k127_4061079_2 enoyl-CoA hydratase K13779 - 4.2.1.57 0.000000000000325 70.0
HSJS2_k127_4064295_0 Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA K00219 - 1.3.1.34 3.53e-317 983.0
HSJS2_k127_4064295_1 Belongs to the thiolase family K00626 - 2.3.1.9 3.417e-235 735.0
HSJS2_k127_4064295_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000002112 267.0
HSJS2_k127_4064295_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005893 259.0
HSJS2_k127_4083446_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 427.0
HSJS2_k127_4083446_1 High frequency lysogenization protein HflD homolog K07153 - - 0.000002145 53.0
HSJS2_k127_4097262_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 3.815e-214 673.0
HSJS2_k127_4097262_1 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000004677 242.0
HSJS2_k127_4100181_0 Bacterial sugar transferase K21303 - 2.7.8.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 442.0
HSJS2_k127_4106800_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1127.0
HSJS2_k127_4106800_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0000096,GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004478,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006556,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009069,GO:0009108,GO:0009116,GO:0009119,GO:0009987,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0019752,GO:0030554,GO:0030955,GO:0031420,GO:0032553,GO:0032555,GO:0032559,GO:0033353,GO:0034641,GO:0035639,GO:0036094,GO:0042278,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046872,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901576,GO:1901605,GO:1901657 2.5.1.6 3.364e-215 672.0
HSJS2_k127_4106800_2 COG0191 Fructose tagatose bisphosphate aldolase K01624 - 4.1.2.13 3.925e-210 655.0
HSJS2_k127_4106800_3 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 2.545e-198 623.0
HSJS2_k127_4106800_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134,K03472 - 1.2.1.12,1.2.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 479.0
HSJS2_k127_4106800_5 ArsR family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 367.0
HSJS2_k127_415535_0 COG0436 Aspartate tyrosine aromatic aminotransferase K12252,K14261 - 2.6.1.84 2.971e-238 739.0
HSJS2_k127_415535_1 homoserine dehydrogenase K00003 - 1.1.1.3 3.399e-195 614.0
HSJS2_k127_415535_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000004723 91.0
HSJS2_k127_429029_0 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 291.0
HSJS2_k127_429029_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000007006 257.0
HSJS2_k127_429029_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000004029 247.0
HSJS2_k127_429029_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000000004172 216.0
HSJS2_k127_429029_4 Domain of unknown function (DUF4399) - - - 0.000000000000000000000000000000000000000000000518 169.0
HSJS2_k127_439124_0 COG0720 6-pyruvoyl-tetrahydropterin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007002 276.0
HSJS2_k127_439124_1 Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides K01465 - 3.5.2.3 0.000000009896 60.0
HSJS2_k127_439124_2 TIGRFAM dihydroorotase, multifunctional complex type K01465 - 3.5.2.3 0.00000002557 59.0
HSJS2_k127_439484_1 protein conserved in bacteria K00243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 317.0
HSJS2_k127_439484_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000484 257.0
HSJS2_k127_439484_3 plasmid stabilization - - - 0.00000000000000000000000000000000000000000000001001 172.0
HSJS2_k127_439484_4 transcriptional regulator - - - 0.00000000000000000000000000000000000000000004538 161.0
HSJS2_k127_439484_5 Protein of unknown function (DUF2750) - - - 0.000000000000000000000000000001705 126.0
HSJS2_k127_444616_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006507 536.0
HSJS2_k127_444616_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 483.0
HSJS2_k127_444616_2 nucleoside-diphosphate sugar epimerase K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 358.0
HSJS2_k127_444616_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001752 286.0
HSJS2_k127_444616_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001805 231.0
HSJS2_k127_444616_6 phosphohistidine phosphatase K08296 - - 0.0000000000002922 72.0
HSJS2_k127_444616_7 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000003113 55.0
HSJS2_k127_445988_0 Pyridine nucleotide-disulphide oxidoreductase K05297 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0015046,GO:0016491,GO:0016730,GO:0016731,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.18.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 554.0
HSJS2_k127_445988_1 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 365.0
HSJS2_k127_445988_2 COG1108 ABC-type Mn2 Zn2 transport systems, permease components K09816 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 338.0
HSJS2_k127_445988_3 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.00000000000000000000000000000000000000000000000000001112 200.0
HSJS2_k127_445988_5 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.000000000000000000000000000000000000000000000000007435 186.0
HSJS2_k127_445988_6 Sugar-binding cellulase-like - - - 0.000000000000000000000000000000000000000003714 162.0
HSJS2_k127_445988_7 rubredoxin - - - 0.0000000000000000000000000005141 114.0
HSJS2_k127_458310_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 469.0
HSJS2_k127_458310_2 negative regulation of transcription, DNA-templated K10917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 348.0
HSJS2_k127_458310_3 COG1283 Na phosphate symporter K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 319.0
HSJS2_k127_458310_4 COG3209 Rhs family protein - - - 0.000000000000000000006095 102.0
HSJS2_k127_458310_6 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000001184 66.0
HSJS2_k127_458310_7 COG3209 Rhs family protein - - - 0.000000002243 65.0
HSJS2_k127_463714_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.802e-216 674.0
HSJS2_k127_463714_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000008859 256.0
HSJS2_k127_463714_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001351 242.0
HSJS2_k127_463714_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000002057 128.0
HSJS2_k127_503183_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003651 282.0
HSJS2_k127_503183_1 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000007935 138.0
HSJS2_k127_503183_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000009398 68.0
HSJS2_k127_513712_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2454.0
HSJS2_k127_513712_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2451.0
HSJS2_k127_513712_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000001374 82.0
HSJS2_k127_520917_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 423.0
HSJS2_k127_520917_1 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 401.0
HSJS2_k127_520917_10 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000005712 83.0
HSJS2_k127_520917_11 chitin binding K21712 - - 0.00000000000003378 76.0
HSJS2_k127_520917_12 Amidohydrolase family - - - 0.000000696 55.0
HSJS2_k127_520917_2 dienelactone hydrolase K21104 - 3.1.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 346.0
HSJS2_k127_520917_3 SpoIIAA-like - - - 0.000000000000000000000000000000000000000000000000000000000000009049 217.0
HSJS2_k127_520917_4 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000001692 218.0
HSJS2_k127_520917_5 Protein of unknown function (DUF1569) - - - 0.0000000000000000000000000000000000000000000000000000005957 198.0
HSJS2_k127_520917_6 Transcription factor zinc-finger - - - 0.00000000000000000000000000000000000000000000000000002423 192.0
HSJS2_k127_520917_7 - - - - 0.000000000000000000000000000000000000000000000000007899 186.0
HSJS2_k127_520917_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000002339 139.0
HSJS2_k127_520917_9 Probable zinc-ribbon domain - - - 0.00000000000000000002507 94.0
HSJS2_k127_522639_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1083.0
HSJS2_k127_522639_1 Belongs to the 'phage' integrase family - - - 1.035e-227 711.0
HSJS2_k127_522639_12 Bacterial regulatory proteins, tetR family K09017 - - 0.00000000004609 71.0
HSJS2_k127_522639_2 protein conserved in bacteria - - - 3.657e-208 653.0
HSJS2_k127_522639_3 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 432.0
HSJS2_k127_522639_4 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008454 283.0
HSJS2_k127_522639_5 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001024 276.0
HSJS2_k127_522639_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001914 243.0
HSJS2_k127_522639_7 ubiquinone biosynthetic process from chorismate K03690 - - 0.00000000000000000000000000000000000000000000000000000000000415 216.0
HSJS2_k127_522639_8 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.000000000000000000000000000000000000000000000008204 177.0
HSJS2_k127_522809_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 5.721e-198 626.0
HSJS2_k127_522809_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 454.0
HSJS2_k127_522809_2 glycosyl transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 363.0
HSJS2_k127_522809_3 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07689 - - 0.000000000000000000000000000000000000000000000000000000000000000000009569 235.0
HSJS2_k127_522809_4 conserved protein involved in intracellular sulfur reduction K07235 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0019417,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055114,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000000000000000000000004903 106.0
HSJS2_k127_524109_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 464.0
HSJS2_k127_524109_1 SAM-dependent K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000003282 267.0
HSJS2_k127_524109_3 - - - - 0.00000001556 60.0
HSJS2_k127_528497_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1279.0
HSJS2_k127_528497_1 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 2.037e-213 669.0
HSJS2_k127_528497_2 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 469.0
HSJS2_k127_528497_3 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 444.0
HSJS2_k127_528497_4 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000902 216.0
HSJS2_k127_528497_5 Repressor involved in choline regulation of the bet genes K02167 - - 0.00000000000000000000000000000000000000000000000004812 186.0
HSJS2_k127_528497_6 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000002229 169.0
HSJS2_k127_528497_7 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000002273 121.0
HSJS2_k127_528497_8 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000005757 63.0
HSJS2_k127_53395_0 Mg2 and Co2 transporter CorB - - - 1.546e-208 655.0
HSJS2_k127_53395_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 542.0
HSJS2_k127_53395_10 Fe-S protein K06938 - - 0.0000000000000001001 82.0
HSJS2_k127_53395_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 453.0
HSJS2_k127_53395_3 ADP-ribose pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 325.0
HSJS2_k127_53395_4 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 304.0
HSJS2_k127_53395_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 289.0
HSJS2_k127_53395_6 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004145 262.0
HSJS2_k127_53395_7 protein conserved in bacteria K11022 - - 0.000000000000000000000000000000000000000001306 158.0
HSJS2_k127_53395_8 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000002504 156.0
HSJS2_k127_53395_9 - - - - 0.000000000000000000000000002442 119.0
HSJS2_k127_535235_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1253.0
HSJS2_k127_535235_1 DNA polymerase K02337 - 2.7.7.7 0.0 1202.0
HSJS2_k127_535235_10 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 386.0
HSJS2_k127_535235_11 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 389.0
HSJS2_k127_535235_12 Belongs to the CDS family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 367.0
HSJS2_k127_535235_13 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 354.0
HSJS2_k127_535235_14 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006551 292.0
HSJS2_k127_535235_15 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002978 277.0
HSJS2_k127_535235_16 Catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002219 268.0
HSJS2_k127_535235_17 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000003955 213.0
HSJS2_k127_535235_18 COG2825 Outer membrane protein K06142 - - 0.000000000000000000000001751 109.0
HSJS2_k127_535235_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1168.0
HSJS2_k127_535235_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 463.0
HSJS2_k127_535235_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 448.0
HSJS2_k127_535235_5 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 448.0
HSJS2_k127_535235_6 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007455 454.0
HSJS2_k127_535235_7 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 448.0
HSJS2_k127_535235_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 424.0
HSJS2_k127_535235_9 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 426.0
HSJS2_k127_547840_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003375 551.0
HSJS2_k127_547840_1 Negative regulator of beta-lactamase expression K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 259.0
HSJS2_k127_547840_2 alanine symporter K03310 - - 0.0000000000000000000000000000000000000000000000000002452 188.0
HSJS2_k127_547840_3 Membrane protein required for beta-lactamase induction K03807 - - 0.0000000000000000000000000000000000000000001509 169.0
HSJS2_k127_548222_0 MMPL family K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 499.0
HSJS2_k127_548222_1 Predicted metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009667 374.0
HSJS2_k127_548222_2 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 350.0
HSJS2_k127_548222_3 Belongs to the thiolase family K00632 GO:0003674,GO:0003824,GO:0003857,GO:0003988,GO:0004300,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033542,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 334.0
HSJS2_k127_548222_4 Pseudomonas avirulence D protein (AvrD) - - - 0.0000000000000000000000000000000000000000000000001465 189.0
HSJS2_k127_548222_5 haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000001227 155.0
HSJS2_k127_548222_6 Autoinducer binding domain - - - 0.000000000000002662 84.0
HSJS2_k127_5548_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.339e-283 889.0
HSJS2_k127_5548_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 1.897e-271 846.0
HSJS2_k127_5548_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 321.0
HSJS2_k127_5548_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008424 299.0
HSJS2_k127_5548_4 cell division protein - - - 0.0000000000000000000000000000000000000000000000000000000000004 216.0
HSJS2_k127_5548_5 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000001328 124.0
HSJS2_k127_56276_0 Acyltransferase - - - 5.906e-319 985.0
HSJS2_k127_56276_1 COG1960 Acyl-CoA dehydrogenases - - - 1.767e-203 637.0
HSJS2_k127_56276_10 - - - - 0.0000000000401 68.0
HSJS2_k127_56276_2 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 370.0
HSJS2_k127_56276_3 Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 366.0
HSJS2_k127_56276_4 COG2818 3-methyladenine DNA glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 290.0
HSJS2_k127_56276_5 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006127 264.0
HSJS2_k127_56276_6 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000004952 189.0
HSJS2_k127_56276_7 - - - - 0.000000000000000000000000000000000000001483 153.0
HSJS2_k127_56276_8 protein conserved in bacteria - - - 0.00000000000000000000000000000000000001096 147.0
HSJS2_k127_56276_9 Phage shock protein A K03615,K03969,K21471 - - 0.0000000000000000000000000000000004707 139.0
HSJS2_k127_562905_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 499.0
HSJS2_k127_562905_1 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 411.0
HSJS2_k127_562905_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 353.0
HSJS2_k127_562905_3 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.000000000000000000000000000000000000000000000000000000000000006321 220.0
HSJS2_k127_562905_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000004004 138.0
HSJS2_k127_564650_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 508.0
HSJS2_k127_564650_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 288.0
HSJS2_k127_564650_2 - - - - 0.0000000000000000000000000000000000000000000000000000000009195 202.0
HSJS2_k127_569701_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1073.0
HSJS2_k127_569701_1 Acetyl-CoA hydrolase - - - 2.041e-246 782.0
HSJS2_k127_569701_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000324 249.0
HSJS2_k127_573665_0 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.0 1185.0
HSJS2_k127_573665_1 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00632 - 2.3.1.16 2.171e-210 659.0
HSJS2_k127_573665_2 Pfam:HipA_N K07154 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 500.0
HSJS2_k127_573665_3 Autotransporter beta-domain - - - 0.00000000000000000000000000000000000000000000000000000000001232 237.0
HSJS2_k127_57457_0 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 316.0
HSJS2_k127_57457_1 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 295.0
HSJS2_k127_57457_2 protein conserved in bacteria K09912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000006005 158.0
HSJS2_k127_57457_3 Phosphate-starvation-inducible E - - - 0.00000000000000000000000000158 113.0
HSJS2_k127_57457_4 Protein of unknown function (DUF3703) - - - 0.0000000000000000000002095 101.0
HSJS2_k127_57457_5 Von Willebrand factor type A K07114 - - 0.00000000000000000004705 105.0
HSJS2_k127_584918_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 1.175e-196 622.0
HSJS2_k127_584918_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001034 250.0
HSJS2_k127_584918_2 Belongs to the UPF0125 (RnfH) family K09801 - - 0.000000000000003802 76.0
HSJS2_k127_590293_0 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000003475 186.0
HSJS2_k127_590293_2 Aminopeptidase - - - 0.00000000000000000000000001242 113.0
HSJS2_k127_604637_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.132e-228 715.0
HSJS2_k127_604637_1 High frequency lysogenization protein HflD homolog K07153 - - 0.00000000000000000000000000000000000000000000003364 177.0
HSJS2_k127_604637_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000004743 132.0
HSJS2_k127_607047_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0003674,GO:0003824,GO:0004642,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1730.0
HSJS2_k127_607047_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 497.0
HSJS2_k127_607047_2 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 466.0
HSJS2_k127_607047_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000000003881 227.0
HSJS2_k127_607047_4 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000000001406 190.0
HSJS2_k127_607769_0 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 0.0 1103.0
HSJS2_k127_607769_1 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 3.802e-264 835.0
HSJS2_k127_615654_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 579.0
HSJS2_k127_615654_1 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 348.0
HSJS2_k127_620113_0 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 404.0
HSJS2_k127_620113_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000005811 164.0
HSJS2_k127_620113_2 Transcriptional K22491 - - 0.00000000000000000000000000001071 130.0
HSJS2_k127_62347_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.843e-240 747.0
HSJS2_k127_62347_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 342.0
HSJS2_k127_62347_2 Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA K11391 - 2.1.1.174 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 319.0
HSJS2_k127_62347_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 307.0
HSJS2_k127_62347_4 Transposase IS200 like - - - 0.00000000000000000000000000000000000000004116 157.0
HSJS2_k127_625054_0 ABC transporter ATP-binding protein - - - 1e-323 995.0
HSJS2_k127_625054_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 5.272e-238 743.0
HSJS2_k127_625054_10 Binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000000000000000000000000000000000000000964 233.0
HSJS2_k127_625054_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000004234 203.0
HSJS2_k127_625054_12 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048027,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000001585 141.0
HSJS2_k127_625054_13 DNA replication, synthesis of RNA primer K02686 GO:0000228,GO:0000428,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005658,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006270,GO:0006276,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016070,GO:0018130,GO:0019438,GO:0030880,GO:0030894,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990077,GO:1990099,GO:1990234,GO:1990837 - 0.00000000000000000000000001139 113.0
HSJS2_k127_625054_15 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.00000000000000005251 85.0
HSJS2_k127_625054_16 Transmembrane anti-sigma factor - - - 0.000003318 52.0
HSJS2_k127_625054_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.084e-232 726.0
HSJS2_k127_625054_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.294e-227 710.0
HSJS2_k127_625054_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007581 468.0
HSJS2_k127_625054_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 404.0
HSJS2_k127_625054_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 370.0
HSJS2_k127_625054_7 Riboflavin synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 350.0
HSJS2_k127_625054_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007553 256.0
HSJS2_k127_625054_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 257.0
HSJS2_k127_638148_0 COG0451 Nucleoside-diphosphate-sugar epimerases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 547.0
HSJS2_k127_638148_1 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 356.0
HSJS2_k127_638148_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 305.0
HSJS2_k127_638148_3 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 301.0
HSJS2_k127_638148_4 rRNA methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000004809 224.0
HSJS2_k127_638148_5 protein conserved in bacteria K09941 - - 0.0000000000000000000000000000000000000000000000000000000000001885 219.0
HSJS2_k127_638148_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000001041 146.0
HSJS2_k127_651492_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.451e-247 774.0
HSJS2_k127_651492_1 Fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 481.0
HSJS2_k127_651492_2 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 428.0
HSJS2_k127_651492_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 395.0
HSJS2_k127_651492_4 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 349.0
HSJS2_k127_651492_5 Transcriptional K03719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007237 248.0
HSJS2_k127_651492_6 Periplasmic or secreted lipoprotein - - - 0.0000001793 57.0
HSJS2_k127_659969_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 469.0
HSJS2_k127_659969_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000002373 189.0
HSJS2_k127_659969_2 pathogenesis - - - 0.000000000000000000001023 102.0
HSJS2_k127_678091_0 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 5.307e-266 829.0
HSJS2_k127_678091_1 esterase of the alpha-beta hydrolase superfamily K07001 - - 3.087e-246 781.0
HSJS2_k127_678091_2 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 478.0
HSJS2_k127_678091_3 SMART HNH nuclease - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000002566 193.0
HSJS2_k127_678091_4 D-alanine [D-alanyl carrier protein] ligase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000009012 90.0
HSJS2_k127_680628_0 phosphoserine phosphatase K01079 - 3.1.3.3 7.314e-210 658.0
HSJS2_k127_692961_0 helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 454.0
HSJS2_k127_692961_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 376.0
HSJS2_k127_692961_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 364.0
HSJS2_k127_692961_3 COG4235, Cytochrome c biogenesis factor K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000001378 239.0
HSJS2_k127_692961_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061603,GO:0070568,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902757,GO:1902758 2.7.7.77 0.000000000000000000000000000000007517 134.0
HSJS2_k127_692961_5 subunit of a heme lyase K02200 - - 0.00000000000000000000000000005071 118.0
HSJS2_k127_707704_0 acyl-CoA thioesterase K01073 - 3.1.2.20 0.0000000000000000000000000000000000000000000000000000000000000006926 228.0
HSJS2_k127_707704_1 Belongs to the DEAD box helicase family - - - 0.00000000000000000000000000000000000000000000786 168.0
HSJS2_k127_707704_2 Transcriptional regulators - - - 0.000000000000000006451 85.0
HSJS2_k127_71548_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 496.0
HSJS2_k127_71548_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 437.0
HSJS2_k127_71548_2 protein conserved in bacteria K03690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004534 277.0
HSJS2_k127_71548_3 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000331 252.0
HSJS2_k127_71548_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000378 251.0
HSJS2_k127_725751_0 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 402.0
HSJS2_k127_725751_1 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000008171 186.0
HSJS2_k127_737786_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K20455 - 4.2.1.117 1.823e-307 945.0
HSJS2_k127_746837_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1806.0
HSJS2_k127_746837_1 carbamoyl-phosphate synthetase glutamine chain K01956 - 6.3.5.5 4.911e-196 617.0
HSJS2_k127_746837_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 394.0
HSJS2_k127_746837_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 315.0
HSJS2_k127_746837_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000000008086 236.0
HSJS2_k127_746837_5 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 - - 0.0000000000000000000000000000000000000000002917 160.0
HSJS2_k127_746837_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000006013 48.0
HSJS2_k127_746967_0 - - - - 5.138e-277 869.0
HSJS2_k127_746967_1 - - - - 9.188e-221 692.0
HSJS2_k127_746967_3 carboxylic ester hydrolase activity K01054 - 3.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 514.0
HSJS2_k127_746967_4 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 418.0
HSJS2_k127_746967_5 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000006562 251.0
HSJS2_k127_749209_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 594.0
HSJS2_k127_749209_1 Catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 591.0
HSJS2_k127_749209_2 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 576.0
HSJS2_k127_749209_3 Belongs to the ArsC family K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000002822 169.0
HSJS2_k127_749209_4 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000000000000000000000000000000000000002266 151.0
HSJS2_k127_751174_0 Histidine kinase K07678 - 2.7.13.3 4.45e-265 844.0
HSJS2_k127_751174_1 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 508.0
HSJS2_k127_751174_2 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 451.0
HSJS2_k127_751174_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 376.0
HSJS2_k127_751174_4 Dynamin family K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 369.0
HSJS2_k127_751174_5 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000271 277.0
HSJS2_k127_751174_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000003899 242.0
HSJS2_k127_751174_7 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000004903 123.0
HSJS2_k127_751174_8 Domain of unknown function (DUF4845) - - - 0.000006361 48.0
HSJS2_k127_753618_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 1.141e-228 715.0
HSJS2_k127_753618_1 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 520.0
HSJS2_k127_753618_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 514.0
HSJS2_k127_753618_3 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 367.0
HSJS2_k127_753618_4 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001093 276.0
HSJS2_k127_753618_5 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001056 278.0
HSJS2_k127_753618_6 COG1846 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000009888 236.0
HSJS2_k127_753618_7 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000000000000000000000000000000000000000000000000000000009699 226.0
HSJS2_k127_753618_8 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.000000000000000000000000000001256 124.0
HSJS2_k127_762229_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.262e-276 856.0
HSJS2_k127_762229_1 Protein of unknown function (DUF3592) - - - 6.684e-202 644.0
HSJS2_k127_762229_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001789 276.0
HSJS2_k127_762229_3 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000103 247.0
HSJS2_k127_769130_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1034.0
HSJS2_k127_769130_1 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005108 382.0
HSJS2_k127_769130_2 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002625 247.0
HSJS2_k127_769130_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000000000000000000000001977 171.0
HSJS2_k127_769130_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0002999 44.0
HSJS2_k127_774249_0 2-oxoglutarate dehydrogenase K00164 - 1.2.4.2 0.0 1645.0
HSJS2_k127_774249_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 5.104e-304 939.0
HSJS2_k127_774249_2 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 4.07e-253 786.0
HSJS2_k127_774249_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.739e-206 646.0
HSJS2_k127_774249_4 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006974 511.0
HSJS2_k127_774249_5 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 455.0
HSJS2_k127_774249_6 succinate dehydrogenase K00241 - - 0.00000000000000000000000000000000000000000000000002203 181.0
HSJS2_k127_774249_7 Membrane-anchoring subunit of succinate dehydrogenase (SDH) K00242 - - 0.0000000000000000000000000000000000000000000004526 169.0
HSJS2_k127_77446_0 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 465.0
HSJS2_k127_77446_1 esterase lipase K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000002743 261.0
HSJS2_k127_77446_2 Protein of unknown function (DUF1449) - - - 0.00000000000000000000000000000000000000000000009322 176.0
HSJS2_k127_77446_3 PspA/IM30 family K03969 - - 0.00000000000000000000000000000001064 135.0
HSJS2_k127_77446_4 flavoprotein involved in K transport - - - 0.0000000000000000000000000000000172 131.0
HSJS2_k127_77446_5 - - - - 0.000000000000007115 82.0
HSJS2_k127_777853_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.346e-271 839.0
HSJS2_k127_777853_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000002523 79.0
HSJS2_k127_787008_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 293.0
HSJS2_k127_787008_1 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001643 253.0
HSJS2_k127_787008_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001152 228.0
HSJS2_k127_787008_3 response to oxidative stress - - - 0.0000000000000000000000000000000006907 135.0
HSJS2_k127_787008_4 - - - - 0.0000000000000000000000002135 116.0
HSJS2_k127_789133_0 metal-dependent phosphoesterases (PHP family) K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 329.0
HSJS2_k127_789133_1 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003516 271.0
HSJS2_k127_789133_2 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000004923 238.0
HSJS2_k127_789133_3 Bacterial SH3 domain K07184 - - 0.000000000000000000000000000000000000000000000000000000000002746 216.0
HSJS2_k127_789133_4 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.00000000000000000000000000000000000000000001052 163.0
HSJS2_k127_79418_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004527,GO:0004529,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0099046,GO:0140097,GO:1901360,GO:1902494 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 584.0
HSJS2_k127_79418_1 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 471.0
HSJS2_k127_79418_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 481.0
HSJS2_k127_79418_3 COG3568 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004743 392.0
HSJS2_k127_79418_4 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 327.0
HSJS2_k127_79418_5 Thiol disulfide interchange protein K03673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003164 279.0
HSJS2_k127_79418_6 COG2863 Cytochrome c553 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009494 256.0
HSJS2_k127_79418_7 ATPase, AAA K06923 - - 0.00000000000000000000000000000000000000000000000000000002164 199.0
HSJS2_k127_79418_8 COG3245 Cytochrome c5 - - - 0.00000000000000000000000000000000000246 140.0
HSJS2_k127_805919_0 in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 582.0
HSJS2_k127_805919_1 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 467.0
HSJS2_k127_805919_2 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 421.0
HSJS2_k127_805919_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 334.0
HSJS2_k127_805919_4 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 330.0
HSJS2_k127_805919_5 heparin binding K03646 - - 0.00000000000000000000000000000000000000000000000000000004201 202.0
HSJS2_k127_812397_0 serine threonine protein kinase K12132 - 2.7.11.1 6.65e-221 720.0
HSJS2_k127_82277_0 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 589.0
HSJS2_k127_82277_1 pilus assembly protein PilN K02663 - - 0.0000000000000000000000000000000000000000000000000000000003486 207.0
HSJS2_k127_82277_2 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000003105 117.0
HSJS2_k127_825422_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 589.0
HSJS2_k127_825422_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009792 486.0
HSJS2_k127_825422_10 Competence protein - - - 0.0000000000000000000000000000000000000000000000004673 183.0
HSJS2_k127_825422_11 FlgJ-related protein K03796 - - 0.00000000000000000000000000000000000000000000004592 179.0
HSJS2_k127_825422_12 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000001087 179.0
HSJS2_k127_825422_13 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000001384 167.0
HSJS2_k127_825422_2 May be involved in recombination K03554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 459.0
HSJS2_k127_825422_3 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 349.0
HSJS2_k127_825422_4 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 340.0
HSJS2_k127_825422_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 312.0
HSJS2_k127_825422_6 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000003507 267.0
HSJS2_k127_825422_8 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000000000000011 206.0
HSJS2_k127_825422_9 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000002294 211.0
HSJS2_k127_84368_0 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 2.778e-255 797.0
HSJS2_k127_84368_1 Domain of Unknown Function (DUF748) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003523 636.0
HSJS2_k127_84368_2 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000473 282.0
HSJS2_k127_84368_3 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000000000000004659 228.0
HSJS2_k127_84368_4 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.0000000000000000000000000000000000004001 141.0
HSJS2_k127_84368_5 protein conserved in bacteria - - - 0.0000000000000000000007888 96.0
HSJS2_k127_84368_7 Outer membrane protein beta-barrel domain - - - 0.000000000016 73.0
HSJS2_k127_845832_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 355.0
HSJS2_k127_845832_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 340.0
HSJS2_k127_845832_2 Involved in the TonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 317.0
HSJS2_k127_845832_3 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001949 269.0
HSJS2_k127_845832_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000001082 221.0
HSJS2_k127_847686_0 MMPL family K07003 - - 1.598e-216 697.0
HSJS2_k127_847686_1 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000006225 235.0
HSJS2_k127_847686_2 - - - - 0.000000000000000000000000000000002001 138.0
HSJS2_k127_847686_3 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0004768 49.0
HSJS2_k127_857317_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009669 360.0
HSJS2_k127_857317_1 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000004634 244.0
HSJS2_k127_864815_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 9.783e-238 743.0
HSJS2_k127_864815_1 general secretion pathway protein K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 557.0
HSJS2_k127_864815_2 chemotaxis K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003247 459.0
HSJS2_k127_864815_3 Sensory box protein response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 454.0
HSJS2_k127_864815_4 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001613 247.0
HSJS2_k127_864815_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005524 235.0
HSJS2_k127_864815_6 Protein-glutamate methylesterase K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000001561 211.0
HSJS2_k127_864815_7 secretion system protein G K02456 - - 0.0000000000000000000137 93.0
HSJS2_k127_867863_0 Tetratricopeptide repeat - - - 7.591e-288 903.0
HSJS2_k127_867863_1 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000004777 207.0
HSJS2_k127_868472_0 Histidine kinase K07636 - 2.7.13.3 5.881e-202 636.0
HSJS2_k127_868472_1 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008907 417.0
HSJS2_k127_868472_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 417.0
HSJS2_k127_869981_0 Concanavalin A-like lectin/glucanases superfamily - - - 4.26e-264 839.0
HSJS2_k127_869981_1 - - - - 0.0000000000000000000000000000000000000008171 149.0
HSJS2_k127_872186_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 531.0
HSJS2_k127_872186_2 transcriptional regulators - - - 0.0000000000000000007453 89.0
HSJS2_k127_872226_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 6.475e-241 752.0
HSJS2_k127_872226_1 - - - - 0.00000000000000002087 85.0
HSJS2_k127_872226_2 Outer membrane protein W K07275 - - 0.0000002274 60.0
HSJS2_k127_894372_0 FAD linked oxidase - - - 9.684e-221 690.0
HSJS2_k127_894372_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.84e-217 679.0
HSJS2_k127_894372_2 COG2267 Lysophospholipase K01048 - 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005088 445.0
HSJS2_k127_894372_3 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 449.0
HSJS2_k127_894372_4 COG3417 Collagen-binding surface adhesin SpaP (antigen I II family) K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 331.0
HSJS2_k127_894372_5 Curli production assembly/transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 306.0
HSJS2_k127_894372_6 A domain family that is part of the cupin metalloenzyme superfamily. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006426 261.0
HSJS2_k127_894372_7 Protein of unknown function (DUF1425) - - - 0.000000000000000000000000000000000000000000000173 172.0
HSJS2_k127_894372_8 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000001901 170.0
HSJS2_k127_894372_9 - - - - 0.0000000000000000000000000003955 124.0
HSJS2_k127_919304_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 559.0
HSJS2_k127_919304_1 transcriptional regulator K03576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 482.0
HSJS2_k127_928884_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 1.699e-195 625.0
HSJS2_k127_928884_1 COG1398 Fatty-acid desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 558.0
HSJS2_k127_928884_2 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.000001235 51.0
HSJS2_k127_929738_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 518.0
HSJS2_k127_929738_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 497.0
HSJS2_k127_929738_2 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 430.0
HSJS2_k127_929738_3 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 435.0
HSJS2_k127_949567_0 membrane K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 378.0
HSJS2_k127_949567_1 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000005131 158.0
HSJS2_k127_95245_0 Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain K03578 - 3.6.4.13 0.0 1501.0
HSJS2_k127_95245_1 protease with the C-terminal PDZ domain - - - 2.088e-262 820.0
HSJS2_k127_95245_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 312.0
HSJS2_k127_95245_11 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006227 277.0
HSJS2_k127_95245_12 protein conserved in bacteria K09929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007478 276.0
HSJS2_k127_95245_13 - - - - 0.00000000000000000000000000000000000836 139.0
HSJS2_k127_95245_14 Belongs to the SUA5 family - - - 0.0000000000000000000000000000009804 122.0
HSJS2_k127_95245_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 2.884e-233 725.0
HSJS2_k127_95245_3 protein conserved in bacteria K09989 - - 1.696e-219 684.0
HSJS2_k127_95245_4 differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs K00648,K16872 - 2.3.1.180,2.3.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 593.0
HSJS2_k127_95245_5 ATPase, AAA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 509.0
HSJS2_k127_95245_6 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 429.0
HSJS2_k127_95245_7 Belongs to the UPF0276 family K09930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 421.0
HSJS2_k127_95245_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 399.0
HSJS2_k127_95245_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 340.0
HSJS2_k127_953833_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 454.0
HSJS2_k127_953833_1 COG0406 Fructose-2,6-bisphosphatase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 327.0
HSJS2_k127_953833_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000001021 251.0
HSJS2_k127_953833_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000202 188.0
HSJS2_k127_954136_0 Alpha beta hydrolase - - - 7.591e-285 882.0
HSJS2_k127_954136_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001383 284.0
HSJS2_k127_954136_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005078 228.0
HSJS2_k127_954136_3 - - - - 0.000000000000000000000000000000000001073 140.0
HSJS2_k127_954136_4 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000001123 134.0
HSJS2_k127_954136_5 protein conserved in bacteria K09954 - - 0.000000000000000000000000000007511 120.0
HSJS2_k127_954136_6 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000003337 117.0
HSJS2_k127_963132_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 3.122e-217 682.0
HSJS2_k127_963132_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 357.0
HSJS2_k127_963132_2 COG3315 O-Methyltransferase involved in polyketide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 353.0
HSJS2_k127_963132_3 serine threonine protein kinase - - - 0.000000000000000000009719 103.0
HSJS2_k127_963132_4 Membrane - - - 0.00000002615 65.0
HSJS2_k127_969050_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1050.0
HSJS2_k127_969050_1 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 381.0
HSJS2_k127_969577_0 Thioredoxin domain-containing protein K05838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 326.0
HSJS2_k127_977394_0 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 8.315e-292 912.0
HSJS2_k127_985779_0 COG0451 Nucleoside-diphosphate-sugar epimerases K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 401.0
HSJS2_k127_985779_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 320.0
HSJS2_k127_985779_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003274 248.0
HSJS2_k127_985779_3 Transposase IS116 IS110 IS902 - - - 0.0000000000000000000000002482 108.0
HSJS2_k127_985779_4 SBF-like CPA transporter family (DUF4137) K03453 - - 0.000000000008711 66.0
HSJS2_k127_986678_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 590.0
HSJS2_k127_986678_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 530.0
HSJS2_k127_986678_2 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 391.0
HSJS2_k127_986678_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000003197 220.0
HSJS2_k127_986678_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000219 194.0
HSJS2_k127_986678_5 EVE domain - - - 0.000000000000000000000000000000000000000000001621 169.0
HSJS2_k127_998881_0 Protein of unknown function (DUF3570) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 467.0
HSJS2_k127_998881_1 Phospholipase K01058 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 379.0
HSJS2_k127_998881_2 Thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000000000000002175 230.0
HSJS2_k127_998881_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000007069 66.0