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Overview

ID MAG01951
Name HSJS3_bin.115
Sample SMP0051
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Pseudomonadales
Family Alcanivoracaceae
Genus JARGOL01
Species
Assembly information
Completeness (%) 69.43
Contamination (%) 3.81
GC content (%) 63.0
N50 (bp) 15,226
Genome size (bp) 2,327,841

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2202

Gene name Description KEGG GOs EC E-value Score Sequence
HSJS3_k127_10048689_0 COG3555 Aspartyl asparaginyl beta-hydroxylase and related dioxygenases K12979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 435.0
HSJS3_k127_10048689_1 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000633 157.0
HSJS3_k127_10048689_2 Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host K05801 - - 0.000000000000005648 77.0
HSJS3_k127_10086118_0 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K13776 - - 0.0 1039.0
HSJS3_k127_10086118_1 Pfam:DUF1446 - - - 8.557e-311 960.0
HSJS3_k127_10086118_2 Acetyl-CoA carboxylase K13778 - 6.4.1.5 1.417e-288 892.0
HSJS3_k127_10086118_3 Acetyl propionyl-CoA carboxylase, alpha subunit K13777 - 6.4.1.5 1.179e-268 842.0
HSJS3_k127_10086118_4 acyl-CoA dehydrogenase K11731 - - 1.704e-209 655.0
HSJS3_k127_10086118_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 501.0
HSJS3_k127_10086118_6 enoyl-CoA hydratase K13779 - 4.2.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 398.0
HSJS3_k127_10086118_7 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001474 267.0
HSJS3_k127_10242919_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 1.718e-196 620.0
HSJS3_k127_10242919_1 Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 535.0
HSJS3_k127_10242919_2 flavoprotein involved in K transport K03379 - 1.14.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 466.0
HSJS3_k127_10242919_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 398.0
HSJS3_k127_10242919_4 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 367.0
HSJS3_k127_10242919_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000003741 126.0
HSJS3_k127_1025062_0 beta-galactosidase - - - 0.0000000000000000000000000000000000000000000003482 192.0
HSJS3_k127_1025062_1 Histidine kinase K20971 - - 0.00000000000000000002444 102.0
HSJS3_k127_1025062_2 flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase K07006 - - 0.000000000007118 67.0
HSJS3_k127_10288223_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 550.0
HSJS3_k127_10288223_1 COG0720 6-pyruvoyl-tetrahydropterin synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 447.0
HSJS3_k127_10288223_2 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 454.0
HSJS3_k127_10288223_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001395 271.0
HSJS3_k127_10288223_4 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain K11444 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000009952 278.0
HSJS3_k127_10288223_5 COG0657 Esterase lipase K14731 - 3.1.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000003676 258.0
HSJS3_k127_10288223_6 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family K02503 - - 0.0000000000000000000000000000000000000000000000000000000000007772 211.0
HSJS3_k127_10288223_7 - - - - 0.00000000000000000000000000000000000000000000000000004069 192.0
HSJS3_k127_10460383_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 1.429e-308 970.0
HSJS3_k127_10460383_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 1.833e-245 765.0
HSJS3_k127_10460383_2 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 353.0
HSJS3_k127_10460383_3 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 337.0
HSJS3_k127_10460383_4 Tetrapyrrole (Corrin/Porphyrin) Methylases K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001864 263.0
HSJS3_k127_10460383_5 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362 - 1.7.1.15 0.00000000000000000000000000000002823 129.0
HSJS3_k127_1140437_0 flavoprotein involved in K transport - - - 3.149e-200 638.0
HSJS3_k127_1140437_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 410.0
HSJS3_k127_1140437_2 COG0514 Superfamily II DNA helicase K03654 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001321 255.0
HSJS3_k127_1140437_3 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000008864 214.0
HSJS3_k127_1140437_4 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000001985 155.0
HSJS3_k127_1140437_5 MAPEG family - - - 0.00000000000000000000000001214 114.0
HSJS3_k127_1157361_0 Acyltransferase - - - 9.562e-267 828.0
HSJS3_k127_1157361_1 Alpha beta hydrolase - - - 2.079e-201 634.0
HSJS3_k127_1157361_10 Transcriptional regulator - - - 0.000000000004876 75.0
HSJS3_k127_1157361_2 Belongs to the glycosyl hydrolase 31 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 603.0
HSJS3_k127_1157361_3 Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009687 492.0
HSJS3_k127_1157361_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 353.0
HSJS3_k127_1157361_5 COG0346 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 333.0
HSJS3_k127_1157361_6 D-arabinono-1,4-lactone oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003802 260.0
HSJS3_k127_1157361_7 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000000000000000000000008277 220.0
HSJS3_k127_1157361_8 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000006469 210.0
HSJS3_k127_1157361_9 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000000000001145 140.0
HSJS3_k127_1346636_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 390.0
HSJS3_k127_1346636_1 helix-turn-helix- domain containing protein AraC type - - - 0.00000000000000000000000000000000000000001037 166.0
HSJS3_k127_1346636_2 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000003509 149.0
HSJS3_k127_1346636_3 FCD K11475 - - 0.00000000000000000000000000000000000009382 153.0
HSJS3_k127_1346636_4 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000006215 105.0
HSJS3_k127_1346636_5 COGs COG1318 transcriptional regulator protein K18546 - - 0.0000000000003602 83.0
HSJS3_k127_1363964_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 4.965e-251 785.0
HSJS3_k127_1363964_1 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 302.0
HSJS3_k127_1363964_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000001651 253.0
HSJS3_k127_1363964_3 - - - - 0.0000000000000000000000000000000000000000000000000000000004242 211.0
HSJS3_k127_1363964_4 - - - - 0.000000000000000000000000000000000000000000000000000006085 193.0
HSJS3_k127_1363964_5 - - - - 0.000000005384 58.0
HSJS3_k127_1363964_6 - - - - 0.0008741 42.0
HSJS3_k127_1374235_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.038e-248 769.0
HSJS3_k127_1374235_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000114 189.0
HSJS3_k127_1374235_2 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.0000003262 52.0
HSJS3_k127_1374241_0 Belongs to the glycosyl hydrolase 31 family K01187,K01811 - 3.2.1.177,3.2.1.20 4.956e-262 826.0
HSJS3_k127_1374241_1 Protein of unknown function (DUF3604) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 484.0
HSJS3_k127_1374241_2 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000001563 192.0
HSJS3_k127_1374241_3 HupE / UreJ protein - - - 0.0000000000000000000000000000000000001392 155.0
HSJS3_k127_1374241_5 COG0760 Parvulin-like peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000002644 132.0
HSJS3_k127_1374241_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000002008 124.0
HSJS3_k127_1374241_7 Transcriptional regulator - - - 0.00000000000000000000004873 111.0
HSJS3_k127_1374241_8 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00007035 49.0
HSJS3_k127_1374241_9 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0001562 45.0
HSJS3_k127_1378995_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 9.676e-245 768.0
HSJS3_k127_1378995_1 GMC oxidoreductase family - - - 5.757e-235 742.0
HSJS3_k127_1378995_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002674 271.0
HSJS3_k127_1378995_3 - - - - 0.00000000000000000000000000000000000000001844 160.0
HSJS3_k127_1378995_4 Multidrug transporter - - - 0.0000000000000000000000000000003059 127.0
HSJS3_k127_1378995_5 belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.000000000000277 69.0
HSJS3_k127_1378995_6 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079 - - 0.000000002604 67.0
HSJS3_k127_1392595_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 1.346e-212 667.0
HSJS3_k127_1392595_1 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 537.0
HSJS3_k127_1392595_10 membrane protein (homolog of Drosophila rhomboid) K02441 - - 0.00000000000000000000000000000000000000000118 169.0
HSJS3_k127_1392595_11 permease - - - 0.000000000000000000000000000000000000000007492 168.0
HSJS3_k127_1392595_12 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000001973 127.0
HSJS3_k127_1392595_13 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000002607 127.0
HSJS3_k127_1392595_14 cyclic nucleotide binding K10914 - - 0.00000000000000000004616 96.0
HSJS3_k127_1392595_2 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 443.0
HSJS3_k127_1392595_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 439.0
HSJS3_k127_1392595_4 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 375.0
HSJS3_k127_1392595_5 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 357.0
HSJS3_k127_1392595_6 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 338.0
HSJS3_k127_1392595_7 Elongation factor P K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001352 267.0
HSJS3_k127_1392595_8 Belongs to the ompA family K03286 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003533 273.0
HSJS3_k127_1392595_9 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000000000000000000000000000003207 220.0
HSJS3_k127_1395676_0 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 9.593e-210 661.0
HSJS3_k127_1395676_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 605.0
HSJS3_k127_1395676_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000003956 219.0
HSJS3_k127_1395676_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.000000000000000000000000000000000000002231 147.0
HSJS3_k127_1449660_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 5.819e-293 910.0
HSJS3_k127_1449660_1 argininosuccinate lyase K01755 - 4.3.2.1 3.736e-228 709.0
HSJS3_k127_1449660_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005872 312.0
HSJS3_k127_1449660_11 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008841 279.0
HSJS3_k127_1449660_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001175 259.0
HSJS3_k127_1449660_13 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000005907 205.0
HSJS3_k127_1449660_14 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.0000000000000000000000000000000000000000000000001262 179.0
HSJS3_k127_1449660_15 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000000000000000000001287 159.0
HSJS3_k127_1449660_16 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000004057 130.0
HSJS3_k127_1449660_17 HxlR-like helix-turn-helix - - - 0.0000000000000000000000198 108.0
HSJS3_k127_1449660_18 - - - - 0.00000000000000001315 95.0
HSJS3_k127_1449660_19 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000000000898 87.0
HSJS3_k127_1449660_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 2.962e-225 702.0
HSJS3_k127_1449660_3 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.122e-197 622.0
HSJS3_k127_1449660_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 578.0
HSJS3_k127_1449660_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008853 480.0
HSJS3_k127_1449660_6 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 442.0
HSJS3_k127_1449660_7 Major royal jelly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 391.0
HSJS3_k127_1449660_8 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 383.0
HSJS3_k127_1449660_9 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 370.0
HSJS3_k127_1459680_0 Trk system potassium uptake protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 544.0
HSJS3_k127_1459680_1 Catalyzes the synthesis of activated sulfate K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000001404 239.0
HSJS3_k127_1459680_2 found to be peripherally associated with the inner membrane in Escherichia coli K03499 - - 0.00000000000000000000000000000000000000006528 151.0
HSJS3_k127_1461007_0 transmembrane signaling receptor activity - - - 0.00000000000000000000000000000000000000000000003024 181.0
HSJS3_k127_1461007_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000006212 151.0
HSJS3_k127_1461007_2 Protein of unknown function (DUF4019) - - - 0.000000000000000000001336 99.0
HSJS3_k127_1486914_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1069.0
HSJS3_k127_1486914_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.352e-280 869.0
HSJS3_k127_1486914_10 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 547.0
HSJS3_k127_1486914_11 outer membrane porin, OprD family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005053 496.0
HSJS3_k127_1486914_12 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 440.0
HSJS3_k127_1486914_13 Belongs to the 3-hydroxyisobutyrate dehydrogenase family K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 392.0
HSJS3_k127_1486914_14 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 389.0
HSJS3_k127_1486914_15 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009898,GO:0009987,GO:0016020,GO:0016310,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019538,GO:0019843,GO:0019897,GO:0019898,GO:0022613,GO:0031234,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0036211,GO:0042254,GO:0042274,GO:0043021,GO:0043024,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044877,GO:0046777,GO:0070181,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 385.0
HSJS3_k127_1486914_16 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 378.0
HSJS3_k127_1486914_17 Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005894 321.0
HSJS3_k127_1486914_18 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 313.0
HSJS3_k127_1486914_19 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006152 287.0
HSJS3_k127_1486914_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 3.04e-280 865.0
HSJS3_k127_1486914_20 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005877 284.0
HSJS3_k127_1486914_21 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001572 266.0
HSJS3_k127_1486914_22 Negative regulator of sigma E activity K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003004 270.0
HSJS3_k127_1486914_23 TetR family transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000377 265.0
HSJS3_k127_1486914_24 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000001919 237.0
HSJS3_k127_1486914_25 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000000000000000000000000003296 224.0
HSJS3_k127_1486914_26 FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000001981 216.0
HSJS3_k127_1486914_27 - - - - 0.000000000000000000000000000000000000002479 150.0
HSJS3_k127_1486914_28 Sigma factor algU negative regulatory protein K03597 - - 0.000000000000000000000000000000000002125 145.0
HSJS3_k127_1486914_29 Positive regulator of K03803 - - 0.000000000000000000000000000000000008137 142.0
HSJS3_k127_1486914_3 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.985e-254 799.0
HSJS3_k127_1486914_30 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000003434 130.0
HSJS3_k127_1486914_31 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000003608 121.0
HSJS3_k127_1486914_32 An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 - 0.0000000000000000832 83.0
HSJS3_k127_1486914_4 exonuclease recJ K07462 - - 9.456e-231 729.0
HSJS3_k127_1486914_5 Tfp pilus assembly protein FimV - - - 9.65e-226 707.0
HSJS3_k127_1486914_6 Histidine kinase K07678 - 2.7.13.3 7.085e-221 702.0
HSJS3_k127_1486914_7 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 604.0
HSJS3_k127_1486914_8 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 579.0
HSJS3_k127_1486914_9 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 560.0
HSJS3_k127_151288_0 Allophanate hydrolase subunit 1 K01941 - 6.3.4.6 0.0 1805.0
HSJS3_k127_151288_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 598.0
HSJS3_k127_151288_2 ABC transporter ATP-binding protein K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007835 442.0
HSJS3_k127_151288_3 COG0600 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 415.0
HSJS3_k127_151288_4 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 401.0
HSJS3_k127_151288_5 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 392.0
HSJS3_k127_151288_6 Domain of unknown function (DUF1989) K09967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 372.0
HSJS3_k127_151288_7 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases K01457 - 3.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000003677 248.0
HSJS3_k127_151288_8 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000005879 202.0
HSJS3_k127_151288_9 - - - - 0.0000001406 57.0
HSJS3_k127_1540479_0 Belongs to the UPF0753 family K09822 - - 8.076e-259 822.0
HSJS3_k127_1540479_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 7.479e-210 655.0
HSJS3_k127_1540479_10 transcriptional regulator K03717 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 351.0
HSJS3_k127_1540479_11 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 338.0
HSJS3_k127_1540479_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 346.0
HSJS3_k127_1540479_13 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 325.0
HSJS3_k127_1540479_14 UPF0114 protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000018 253.0
HSJS3_k127_1540479_15 Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins K13643 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001219 241.0
HSJS3_k127_1540479_16 SufE protein probably involved in Fe-S center assembly K02426 - - 0.00000000000000000000000000000000000000000000000000000000000004368 216.0
HSJS3_k127_1540479_17 membrane protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000006103 219.0
HSJS3_k127_1540479_18 YHYH protein - - - 0.0000000000000000000000000000000000000001087 163.0
HSJS3_k127_1540479_19 Preprotein translocase subunit YajC K03210 - - 0.000000000000000000000000000000000000008704 147.0
HSJS3_k127_1540479_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003672 515.0
HSJS3_k127_1540479_20 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000004817 144.0
HSJS3_k127_1540479_21 COG1734 DnaK suppressor protein - - - 0.0000000000000000000000000000000002829 134.0
HSJS3_k127_1540479_22 Protein of unknown function (DUF465) K09794 - - 0.00000000000000000000007536 109.0
HSJS3_k127_1540479_23 UPF0391 membrane protein - - - 0.00000000000000001406 84.0
HSJS3_k127_1540479_24 - - - - 0.00001409 51.0
HSJS3_k127_1540479_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 GO:0001522,GO:0003674,GO:0003824,GO:0004123,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006790,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009000,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016226,GO:0016740,GO:0016769,GO:0016782,GO:0016783,GO:0016829,GO:0016846,GO:0018130,GO:0018131,GO:0019842,GO:0022607,GO:0030170,GO:0031071,GO:0031119,GO:0031163,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0048037,GO:0050662,GO:0051186,GO:0070279,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0097163,GO:0140104,GO:1901360,GO:1901363 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 500.0
HSJS3_k127_1540479_4 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 441.0
HSJS3_k127_1540479_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 435.0
HSJS3_k127_1540479_6 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 418.0
HSJS3_k127_1540479_7 NADH ubiquinone oxidoreductase subunit 5 (Chain L) multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 431.0
HSJS3_k127_1540479_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 389.0
HSJS3_k127_1540479_9 Aminotransferase class-III K00836 - 2.6.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 381.0
HSJS3_k127_1569686_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3e-323 996.0
HSJS3_k127_1569686_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.418e-291 901.0
HSJS3_k127_1569686_10 Protein of unknown function (DUF2806) - - - 0.0000000000000351 84.0
HSJS3_k127_1569686_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0005123 43.0
HSJS3_k127_1569686_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 596.0
HSJS3_k127_1569686_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 426.0
HSJS3_k127_1569686_4 Transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003832 388.0
HSJS3_k127_1569686_5 Domain of unknown function (DUF4062) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 332.0
HSJS3_k127_1569686_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001566 282.0
HSJS3_k127_1569686_7 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003903 263.0
HSJS3_k127_1569686_8 Bacterial DNA-binding protein - - - 0.0000000000000000000000000000000000000000000164 167.0
HSJS3_k127_1569686_9 Aminopeptidase - - - 0.00000000000000000000000000000004175 127.0
HSJS3_k127_1595829_0 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 4.279e-211 663.0
HSJS3_k127_1595829_1 accessory protein K06959 - - 0.0000000000000000000000000000000000000001446 153.0
HSJS3_k127_1596003_0 COG0464 ATPases of the AAA class - - - 1.384e-199 634.0
HSJS3_k127_1596003_1 Histidine kinase K20972,K20973 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 537.0
HSJS3_k127_1596003_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 495.0
HSJS3_k127_1596003_3 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 416.0
HSJS3_k127_1596003_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 315.0
HSJS3_k127_1596003_5 redox protein, regulator of disulfide bond formation K07397 - - 0.000000000000000000000000000000000000000000000000000000000003316 211.0
HSJS3_k127_1596003_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000003516 198.0
HSJS3_k127_1735288_0 secretion pathway protein K02453 - - 7.311e-263 829.0
HSJS3_k127_1735288_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 604.0
HSJS3_k127_1735288_10 - - - - 0.0000000000000000000000000000002633 136.0
HSJS3_k127_1735288_11 LuxR family transcriptional regulator K04333,K20918 - - 0.000000000000000003047 87.0
HSJS3_k127_1735288_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 511.0
HSJS3_k127_1735288_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 377.0
HSJS3_k127_1735288_4 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008035 343.0
HSJS3_k127_1735288_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005851 242.0
HSJS3_k127_1735288_6 Type II secretion system protein C K02452 - - 0.00000000000000000000000000000000000000000000000000000000000000000001189 243.0
HSJS3_k127_1735288_8 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000006673 169.0
HSJS3_k127_1735288_9 Type II secretion system (T2SS), protein N K02463 - - 0.000000000000000000000000000000000005461 149.0
HSJS3_k127_175263_0 Part of a membrane complex involved in electron transport K03615 - - 4.783e-283 895.0
HSJS3_k127_175263_1 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 518.0
HSJS3_k127_175263_2 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 374.0
HSJS3_k127_175263_3 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 346.0
HSJS3_k127_175263_4 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 331.0
HSJS3_k127_175263_5 Part of a membrane complex involved in electron transport K03612 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 307.0
HSJS3_k127_175263_6 6-phosphogluconolactonase activity K07404 - 3.1.1.31 0.00000003189 58.0
HSJS3_k127_1758855_0 UPF0313 protein - - - 0.0 1214.0
HSJS3_k127_1758855_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 565.0
HSJS3_k127_1758855_11 - - - - 0.0000000000000000000000000000000000002459 148.0
HSJS3_k127_1758855_2 Electron transfer flavoprotein K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 496.0
HSJS3_k127_1758855_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 397.0
HSJS3_k127_1758855_4 of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 385.0
HSJS3_k127_1758855_5 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 355.0
HSJS3_k127_1758855_6 Metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008882 327.0
HSJS3_k127_1758855_7 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000846 254.0
HSJS3_k127_1758855_8 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000003758 225.0
HSJS3_k127_1758855_9 dienelactone hydrolase K21104 - 3.1.1.101 0.000000000000000000000000000000000000000000000000000000000002181 219.0
HSJS3_k127_1849450_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.84e-319 985.0
HSJS3_k127_1849450_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 9.423e-270 844.0
HSJS3_k127_1849450_10 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000001312 199.0
HSJS3_k127_1849450_11 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000001277 211.0
HSJS3_k127_1849450_12 Putative inner membrane exporter, YdcZ K09936 - - 0.000000000000000000000000000000000000000000001007 169.0
HSJS3_k127_1849450_13 PFAM transferase hexapeptide repeat containing protein K00661 - 2.3.1.79 0.00000000000000000000000000000000207 139.0
HSJS3_k127_1849450_14 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000006656 140.0
HSJS3_k127_1849450_15 Belongs to the 4-oxalocrotonate tautomerase family K01821 - 5.3.2.6 0.000000000000000000000000003668 112.0
HSJS3_k127_1849450_16 Catalyzes the first step in the glyoxalate cycle, which converts lipids to carbohydrates K01637 - 4.1.3.1 0.0000000000000000001883 87.0
HSJS3_k127_1849450_17 Small multidrug resistance protein K11741 - - 0.0000000000000003944 83.0
HSJS3_k127_1849450_19 TIGRFAM PEP-CTERM protein sorting domain - - - 0.000000004458 65.0
HSJS3_k127_1849450_2 belongs to the aldehyde dehydrogenase family - - - 5.084e-268 829.0
HSJS3_k127_1849450_3 beta-lactamase K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 616.0
HSJS3_k127_1849450_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 574.0
HSJS3_k127_1849450_5 Na+/Pi-cotransporter K03324 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 559.0
HSJS3_k127_1849450_6 COG2148 Sugar transferases involved in lipopolysaccharide synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 449.0
HSJS3_k127_1849450_7 COG0534 Na -driven multidrug efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 415.0
HSJS3_k127_1849450_8 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 372.0
HSJS3_k127_1849450_9 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002813 232.0
HSJS3_k127_186734_0 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 4.974e-227 726.0
HSJS3_k127_186734_1 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 0.0000000000000000000000000000000009226 130.0
HSJS3_k127_186734_2 COG0457 FOG TPR repeat - - - 0.00000000000000000000000002586 113.0
HSJS3_k127_186734_3 Glutaredoxin - - - 0.00000000000002195 77.0
HSJS3_k127_1886675_0 Involved in the post-transcriptional processing of the daa operon mRNA, which encodes proteins involved in fimbrial biogenesis of an enteropathogenic E. coli strain K03578 - 3.6.4.13 0.0 1541.0
HSJS3_k127_1886675_1 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 0.0 1134.0
HSJS3_k127_1886675_10 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 323.0
HSJS3_k127_1886675_11 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 266.0
HSJS3_k127_1886675_12 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000003553 253.0
HSJS3_k127_1886675_13 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001734 238.0
HSJS3_k127_1886675_14 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000002656 233.0
HSJS3_k127_1886675_15 Pfam:DUF46 - - - 0.00000000000000000000000000000000000000000000000000009871 199.0
HSJS3_k127_1886675_16 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.000000000000000000000000000000000000000000000003957 186.0
HSJS3_k127_1886675_17 Ion channel - - - 0.00000000000000000000000001179 115.0
HSJS3_k127_1886675_18 carboxylic ester hydrolase activity - - - 0.0000000000000000000000008377 106.0
HSJS3_k127_1886675_19 - - - - 0.000000000000000000001597 98.0
HSJS3_k127_1886675_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007,K21787 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016999,GO:0017000,GO:0017144,GO:0044237,GO:0044249 2.7.9.2 0.0 1101.0
HSJS3_k127_1886675_20 SNARE associated Golgi protein - - - 0.00008037 53.0
HSJS3_k127_1886675_3 protease with the C-terminal PDZ domain - - - 4.471e-265 828.0
HSJS3_k127_1886675_4 protein conserved in bacteria K09989 - - 1.7e-214 670.0
HSJS3_k127_1886675_5 differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs K00648,K16872 - 2.3.1.180,2.3.1.207 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002737 592.0
HSJS3_k127_1886675_6 exporters of the RND superfamily K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 587.0
HSJS3_k127_1886675_7 ATPase, AAA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 510.0
HSJS3_k127_1886675_8 PFAM AMP-dependent synthetase and ligase K22319 - 6.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 421.0
HSJS3_k127_1886675_9 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 374.0
HSJS3_k127_1924114_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.204e-241 751.0
HSJS3_k127_1924114_1 COG0642 Signal transduction histidine kinase - - - 1.41e-234 752.0
HSJS3_k127_1924114_2 COG0642 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 533.0
HSJS3_k127_1924114_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000009596 190.0
HSJS3_k127_1945759_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.439e-272 843.0
HSJS3_k127_1945759_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 3.129e-208 650.0
HSJS3_k127_1945759_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 597.0
HSJS3_k127_1945759_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 587.0
HSJS3_k127_1945759_4 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 461.0
HSJS3_k127_1945759_5 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 426.0
HSJS3_k127_1945759_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002957 354.0
HSJS3_k127_1945759_7 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000008592 143.0
HSJS3_k127_1981526_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 2.779e-320 996.0
HSJS3_k127_1981526_1 Esterase lipase K14731 - 3.1.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 371.0
HSJS3_k127_1981526_2 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 361.0
HSJS3_k127_1981526_3 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002478 356.0
HSJS3_k127_1981526_4 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 293.0
HSJS3_k127_1981526_5 transcriptional regulator K03576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003241 279.0
HSJS3_k127_1981526_6 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006744 256.0
HSJS3_k127_1981526_7 Metallopeptidase family M24 - - - 0.000000000000000000000000001312 122.0
HSJS3_k127_1981526_8 - - - - 0.0000006066 51.0
HSJS3_k127_1993644_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 1.827e-206 647.0
HSJS3_k127_1993644_1 phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 317.0
HSJS3_k127_1993644_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000008375 227.0
HSJS3_k127_1993644_3 membrane K08973 - - 0.0000000000000000002872 87.0
HSJS3_k127_2012259_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 8.763e-244 760.0
HSJS3_k127_2012259_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 501.0
HSJS3_k127_2012259_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 406.0
HSJS3_k127_2012259_3 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 342.0
HSJS3_k127_2012259_4 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 338.0
HSJS3_k127_2012259_5 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000004492 87.0
HSJS3_k127_2044547_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1173.0
HSJS3_k127_2044547_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002017 252.0
HSJS3_k127_2044547_2 TrkA-C domain - - - 0.000000000000000000000000000000000001006 140.0
HSJS3_k127_2072598_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 336.0
HSJS3_k127_2072598_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006796 269.0
HSJS3_k127_2072598_2 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
HSJS3_k127_2072598_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000001497 191.0
HSJS3_k127_2072598_4 Molybdenum cofactor biosynthesis protein K03635 - 2.8.1.12 0.00000000000000000000000000000000003412 139.0
HSJS3_k127_2072598_5 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000001148 83.0
HSJS3_k127_2136752_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 4.458e-196 615.0
HSJS3_k127_2136752_1 domain, Protein K11045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008681 276.0
HSJS3_k127_2136752_2 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000001313 196.0
HSJS3_k127_2136752_3 Jacalin-like lectin domain - - - 0.0000000000000000003075 102.0
HSJS3_k127_2136752_4 Modulates RecA activity K03565 GO:0003674,GO:0005488,GO:0005515,GO:0006282,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0048583,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0071496,GO:0080090,GO:0080134,GO:0080135,GO:0098772,GO:2001020 - 0.0000000000000005864 80.0
HSJS3_k127_2142300_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.187e-221 691.0
HSJS3_k127_2142300_1 Acts as a magnesium transporter K06213 - - 4.78e-209 657.0
HSJS3_k127_2142300_10 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 374.0
HSJS3_k127_2142300_11 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 355.0
HSJS3_k127_2142300_12 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006527 327.0
HSJS3_k127_2142300_13 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000613 229.0
HSJS3_k127_2142300_14 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.00000000000000000000000000000000000000000000000000000000000005048 220.0
HSJS3_k127_2142300_15 PTS fructose transporter subunit IIA K02806 - - 0.00000000000000000000000000000000000000000000000000000000008463 208.0
HSJS3_k127_2142300_16 seems to be involved in modulation of the sigma(54) (RpoN) activity for quorum sensing K05808 - - 0.0000000000000000000000000000000000000000000000005707 179.0
HSJS3_k127_2142300_17 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm K09774 - - 0.00000000000000000000000000002451 123.0
HSJS3_k127_2142300_18 Belongs to the BolA IbaG family - - - 0.0000000000000000000000001348 111.0
HSJS3_k127_2142300_19 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.0000000000000000000000001742 113.0
HSJS3_k127_2142300_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 4.018e-196 619.0
HSJS3_k127_2142300_20 Phosphocarrier protein HPr K08485,K11189 - - 0.0000000000000000000000003532 109.0
HSJS3_k127_2142300_3 Protease involved in proteolytic processing of the antibiotic Microcin B17 and in sensitivity to the DNA gyrase inhibitor LetD K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006786 542.0
HSJS3_k127_2142300_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005975 538.0
HSJS3_k127_2142300_5 Belongs to the peptidase S1C family K04691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007733 491.0
HSJS3_k127_2142300_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008124 486.0
HSJS3_k127_2142300_7 Arabinose 5-phosphate isomerase K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 483.0
HSJS3_k127_2142300_8 ABC transporter ATP-binding protein K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 418.0
HSJS3_k127_2142300_9 metal-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 411.0
HSJS3_k127_2162108_0 COG2368 Aromatic ring hydroxylase - - - 2.808e-303 935.0
HSJS3_k127_2162108_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 9.326e-233 724.0
HSJS3_k127_2162108_10 Polysaccharide biosynthesis protein K15894 - 4.2.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 532.0
HSJS3_k127_2162108_11 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 556.0
HSJS3_k127_2162108_12 PFAM NAD dependent epimerase dehydratase family K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 518.0
HSJS3_k127_2162108_13 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 471.0
HSJS3_k127_2162108_14 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 469.0
HSJS3_k127_2162108_15 COG0451 Nucleoside-diphosphate-sugar epimerases K19068 - 1.1.1.367 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 464.0
HSJS3_k127_2162108_16 Glycosyl transferase 4-like domain K03208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 447.0
HSJS3_k127_2162108_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009924 415.0
HSJS3_k127_2162108_18 Acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 408.0
HSJS3_k127_2162108_19 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 405.0
HSJS3_k127_2162108_2 ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component K02004 - - 2.292e-215 695.0
HSJS3_k127_2162108_20 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 409.0
HSJS3_k127_2162108_21 transferase activity, transferring amino-acyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005212 398.0
HSJS3_k127_2162108_22 Small-conductance mechanosensitive channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 387.0
HSJS3_k127_2162108_23 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 379.0
HSJS3_k127_2162108_24 helix_turn_helix, arabinose operon control protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 369.0
HSJS3_k127_2162108_25 Catalyzes the transfer of the GlcNAc-1-phosphate moiety from UDP-GlcNAc onto the carrier lipid undecaprenyl phosphate (C55-P), yielding GlcNAc-pyrophosphoryl-undecaprenyl (GlcNAc-PP- C55) K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 364.0
HSJS3_k127_2162108_26 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 357.0
HSJS3_k127_2162108_27 COG0110 Acetyltransferase (isoleucine patch superfamily) K13018 - 2.3.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 345.0
HSJS3_k127_2162108_28 metal-dependent phosphoesterases (PHP family) K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 350.0
HSJS3_k127_2162108_29 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 341.0
HSJS3_k127_2162108_3 Neutral/alkaline non-lysosomal ceramidase, N-terminal K12349 - 3.5.1.23 4.896e-211 676.0
HSJS3_k127_2162108_30 Male sterility protein K00091,K01784 - 1.1.1.219,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 327.0
HSJS3_k127_2162108_31 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 295.0
HSJS3_k127_2162108_32 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008495 278.0
HSJS3_k127_2162108_33 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001053 286.0
HSJS3_k127_2162108_34 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002464 273.0
HSJS3_k127_2162108_35 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001297 262.0
HSJS3_k127_2162108_36 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003355 249.0
HSJS3_k127_2162108_37 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000003809 252.0
HSJS3_k127_2162108_38 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000002794 248.0
HSJS3_k127_2162108_39 COG2755 Lysophospholipase L1 and related esterases K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000003739 238.0
HSJS3_k127_2162108_4 Polysaccharide biosynthesis protein - - - 8.258e-199 638.0
HSJS3_k127_2162108_40 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000731 243.0
HSJS3_k127_2162108_42 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000001323 226.0
HSJS3_k127_2162108_43 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000000000000002806 211.0
HSJS3_k127_2162108_44 SH3 domain protein K07184 - - 0.00000000000000000000000000000000000000000000000000006806 194.0
HSJS3_k127_2162108_45 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000001186 183.0
HSJS3_k127_2162108_46 - - - - 0.00000000000000000000000000000000000000000000001042 183.0
HSJS3_k127_2162108_47 O-acyltransferase activity K00661 - 2.3.1.79 0.00000000000000000000000000000000000002105 149.0
HSJS3_k127_2162108_48 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000001173 149.0
HSJS3_k127_2162108_5 Belongs to the UDP-N-acetylglucosamine 2-epimerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 608.0
HSJS3_k127_2162108_50 competence protein ComEA K02237 - - 0.000000000000001979 81.0
HSJS3_k127_2162108_51 Domain of unknown function (DUF4124) - - - 0.000009817 54.0
HSJS3_k127_2162108_52 - - - - 0.00006777 50.0
HSJS3_k127_2162108_6 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 601.0
HSJS3_k127_2162108_7 carnitine dehydratase K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 558.0
HSJS3_k127_2162108_8 Oxidoreductase family, C-terminal alpha/beta domain K13016 - 1.1.1.335 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 541.0
HSJS3_k127_2162108_9 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 539.0
HSJS3_k127_2206789_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 583.0
HSJS3_k127_2206789_1 COG3639 ABC-type phosphate phosphonate transport system, permease component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 567.0
HSJS3_k127_2206789_10 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000001007 209.0
HSJS3_k127_2206789_11 SMART AAA ATPase K02041 - 3.6.3.28 0.00000000000000000000000000000000000003791 154.0
HSJS3_k127_2206789_12 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000001094 127.0
HSJS3_k127_2206789_13 COG2015, Alkyl sulfatase and related hydrolases K01138 - - 0.00000000000000000000004374 102.0
HSJS3_k127_2206789_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 549.0
HSJS3_k127_2206789_3 fatty acid desaturase K00508 - 1.14.19.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 496.0
HSJS3_k127_2206789_4 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 486.0
HSJS3_k127_2206789_5 Acyl dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 448.0
HSJS3_k127_2206789_6 desaturase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 443.0
HSJS3_k127_2206789_7 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 382.0
HSJS3_k127_2206789_8 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 301.0
HSJS3_k127_2206789_9 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003842 285.0
HSJS3_k127_2343891_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1264.0
HSJS3_k127_2343891_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1137.0
HSJS3_k127_2343891_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 3.184e-219 681.0
HSJS3_k127_2343891_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006439 445.0
HSJS3_k127_2343891_4 Amino Acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 349.0
HSJS3_k127_2343891_5 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 297.0
HSJS3_k127_2343891_6 esterase K07000 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 290.0
HSJS3_k127_2343891_7 protein conserved in bacteria K09920 - - 0.000000000000000000000000000000000000000004732 159.0
HSJS3_k127_2346491_0 helicase K03722 - 3.6.4.12 1.138e-274 859.0
HSJS3_k127_2346491_1 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000000000000000003712 226.0
HSJS3_k127_2346491_2 Peptidase M22 K14742 - - 0.00000000000000000000000000000000000000000000000000000001373 207.0
HSJS3_k127_2356384_0 Uncharacterized protein conserved in bacteria (DUF2236) - - - 1.898e-201 637.0
HSJS3_k127_2356384_1 - - - - 0.00000000000000000000000000000000000000001926 154.0
HSJS3_k127_2477303_0 multicopper oxidases - - - 4.496e-287 893.0
HSJS3_k127_2477303_1 protein possibly involved in aromatic compounds catabolism - - - 0.000000000000000000000000000000000000000000000002705 179.0
HSJS3_k127_2477303_2 Protein of unknown function, DUF393 - - - 0.000000000000000000000000006018 115.0
HSJS3_k127_2477303_4 Copper resistance protein B precursor (CopB) K07233 - - 0.000000725 55.0
HSJS3_k127_2534193_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 3.32e-252 782.0
HSJS3_k127_2534193_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 451.0
HSJS3_k127_2534193_2 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 427.0
HSJS3_k127_2534193_3 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 349.0
HSJS3_k127_2534193_4 Protein of unknown function (DUF3426) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 321.0
HSJS3_k127_2534193_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 GO:0000287,GO:0003674,GO:0003824,GO:0004427,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006793,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050355 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 298.0
HSJS3_k127_2534193_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 GO:0002943,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0016491,GO:0016627,GO:0017150,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050896,GO:0055114,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000008717 251.0
HSJS3_k127_2534193_7 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000004925 234.0
HSJS3_k127_2534193_8 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000001862 200.0
HSJS3_k127_2534193_9 pathogenesis - - - 0.0000000000004861 77.0
HSJS3_k127_2705365_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 5.459e-283 880.0
HSJS3_k127_2705365_1 Amidohydrolase family - - - 4.487e-252 789.0
HSJS3_k127_2705365_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 400.0
HSJS3_k127_2705365_11 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 352.0
HSJS3_k127_2705365_12 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 337.0
HSJS3_k127_2705365_13 Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer K22105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001921 279.0
HSJS3_k127_2705365_14 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001136 270.0
HSJS3_k127_2705365_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000007135 250.0
HSJS3_k127_2705365_16 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000000000000000000003282 192.0
HSJS3_k127_2705365_17 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000009591 144.0
HSJS3_k127_2705365_18 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000003201 147.0
HSJS3_k127_2705365_19 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000001757 138.0
HSJS3_k127_2705365_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 5.369e-230 718.0
HSJS3_k127_2705365_20 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.0000003161 54.0
HSJS3_k127_2705365_21 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.0004828 44.0
HSJS3_k127_2705365_3 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 542.0
HSJS3_k127_2705365_4 desaturase K00508 - 1.14.19.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 536.0
HSJS3_k127_2705365_5 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 513.0
HSJS3_k127_2705365_6 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 514.0
HSJS3_k127_2705365_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 446.0
HSJS3_k127_2705365_8 transcriptional regulator K13633 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 432.0
HSJS3_k127_2705365_9 HflC and HflK could encode or regulate a protease K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 423.0
HSJS3_k127_2717368_0 ATPase with chaperone activity K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 539.0
HSJS3_k127_2717368_1 Aminoglycoside phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 428.0
HSJS3_k127_2717368_2 protein conserved in bacteria K09806 - - 0.00000000000000000001411 96.0
HSJS3_k127_2717368_3 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 0.000000000000000000636 85.0
HSJS3_k127_2717368_4 Ankyrin repeat domain-containing protein 50-like K21440 - - 0.00000000000009173 85.0
HSJS3_k127_2724017_0 Belongs to the beta-ketoacyl-ACP synthases family K18473 - 2.3.1.180 4.518e-238 754.0
HSJS3_k127_2724017_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 3.791e-212 665.0
HSJS3_k127_2724017_10 Protein of unknown function (DUF1289) K06938 - - 0.0000000000000000000000000000000000000000000000000000000000007077 216.0
HSJS3_k127_2724017_11 sterol desaturase - - - 0.0000000000000000000000000000000000000000000000000000000002749 212.0
HSJS3_k127_2724017_12 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.00000000000000000000000000000000006065 145.0
HSJS3_k127_2724017_13 - - - - 0.000000000000000000000000000002139 121.0
HSJS3_k127_2724017_14 glyoxalase III activity - - - 0.00000000000000000000000002898 114.0
HSJS3_k127_2724017_15 Domain of unknown function (DUF3520) K07114 - - 0.0000000000000000000000008736 104.0
HSJS3_k127_2724017_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 431.0
HSJS3_k127_2724017_3 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 353.0
HSJS3_k127_2724017_4 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 336.0
HSJS3_k127_2724017_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 308.0
HSJS3_k127_2724017_6 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007258 293.0
HSJS3_k127_2724017_7 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000015 286.0
HSJS3_k127_2724017_8 Protein of unknown function (DUF2846) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004599 275.0
HSJS3_k127_2724017_9 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000007617 235.0
HSJS3_k127_2736988_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 3.36e-252 785.0
HSJS3_k127_2736988_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 7.375e-212 666.0
HSJS3_k127_2736988_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 417.0
HSJS3_k127_2736988_3 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001485 273.0
HSJS3_k127_2736988_4 Bacterial protein of unknown function (Gcw_chp) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001933 263.0
HSJS3_k127_2736988_5 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004333 241.0
HSJS3_k127_2736988_7 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide K02439 - 2.8.1.1 0.000000000000000000000000000006149 124.0
HSJS3_k127_2753387_0 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 586.0
HSJS3_k127_2753387_1 COG3243 Poly(3-hydroxyalkanoate) synthetase K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 466.0
HSJS3_k127_2753387_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 374.0
HSJS3_k127_2753387_3 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008597 243.0
HSJS3_k127_2753387_4 SMART Transcription regulator, AsnC-type K03719 - - 0.000000000000000000000000000000000000000000000000000000000000000000001872 242.0
HSJS3_k127_2753387_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. TPMT family K00569 - 2.1.1.67 0.0000000000000000000000000000000000000000000000000000000005285 209.0
HSJS3_k127_2753387_6 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004141,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017076,GO:0017144,GO:0018130,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000004912 167.0
HSJS3_k127_2758184_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.233e-242 754.0
HSJS3_k127_2758184_1 Acetyl-coenzyme A transporter 1 K08218 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015835,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1901264,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 496.0
HSJS3_k127_2758184_2 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 409.0
HSJS3_k127_2758184_3 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 401.0
HSJS3_k127_2758184_4 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 341.0
HSJS3_k127_2758184_5 Heme iron utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000835 231.0
HSJS3_k127_2758184_6 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000002072 205.0
HSJS3_k127_2758184_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000000002987 179.0
HSJS3_k127_2758184_8 Methyltransferase K07443 - - 0.00000000000000000000000000391 123.0
HSJS3_k127_2759893_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.921e-250 780.0
HSJS3_k127_2759893_1 Belongs to the RimK family K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 530.0
HSJS3_k127_2759893_2 Deacylase K06987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 501.0
HSJS3_k127_2759893_3 6-phosphogluconolactonase activity K07404 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 452.0
HSJS3_k127_2759893_4 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 400.0
HSJS3_k127_2759893_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 374.0
HSJS3_k127_2759893_6 Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis K03683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 338.0
HSJS3_k127_2759893_7 protein conserved in archaea - - - 0.0000000000000000000000000000000000000000000000000000000001335 207.0
HSJS3_k127_2759893_8 PepSY-associated TM region - - - 0.00000000000000000000000000001211 122.0
HSJS3_k127_2798584_0 Alpha beta hydrolase - - - 5.48e-208 653.0
HSJS3_k127_2798584_1 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000947 588.0
HSJS3_k127_2798584_2 Catalyzes the formation of acetoacetate and acetyl-CoA from 3-hydroxy-3-methylglutaryl-CoA K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 495.0
HSJS3_k127_2798584_3 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 363.0
HSJS3_k127_2798584_4 COG0346 Lactoylglutathione lyase and related lyases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 335.0
HSJS3_k127_2798584_5 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000000000000000000000005464 216.0
HSJS3_k127_2798584_6 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000000000000069 143.0
HSJS3_k127_2798584_7 D-arabinono-1,4-lactone oxidase - - - 0.00000007594 61.0
HSJS3_k127_2800587_0 ABC transporter ATP-binding protein K06158 - - 1.55e-243 769.0
HSJS3_k127_2800587_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 591.0
HSJS3_k127_2800587_2 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004552 274.0
HSJS3_k127_2800587_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000159 258.0
HSJS3_k127_2800587_4 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001764 257.0
HSJS3_k127_2800587_5 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 K03773 - 5.2.1.8 0.000000000000001731 79.0
HSJS3_k127_2960450_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1065.0
HSJS3_k127_2960450_1 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 0.0 1021.0
HSJS3_k127_2960450_10 Belongs to the binding-protein-dependent transport system permease family K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 580.0
HSJS3_k127_2960450_11 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006803 554.0
HSJS3_k127_2960450_12 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 540.0
HSJS3_k127_2960450_13 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007831 517.0
HSJS3_k127_2960450_14 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 497.0
HSJS3_k127_2960450_15 Zn-dependent protease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 477.0
HSJS3_k127_2960450_16 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 426.0
HSJS3_k127_2960450_17 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 402.0
HSJS3_k127_2960450_18 pfam abc K11962 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 404.0
HSJS3_k127_2960450_19 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 394.0
HSJS3_k127_2960450_2 Dehydratase family K01687 - 4.2.1.9 4.229e-294 909.0
HSJS3_k127_2960450_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 392.0
HSJS3_k127_2960450_21 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005873 379.0
HSJS3_k127_2960450_22 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 367.0
HSJS3_k127_2960450_23 ABC transporter K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 360.0
HSJS3_k127_2960450_24 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 342.0
HSJS3_k127_2960450_25 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 323.0
HSJS3_k127_2960450_26 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006392 278.0
HSJS3_k127_2960450_27 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004564 271.0
HSJS3_k127_2960450_28 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000173 265.0
HSJS3_k127_2960450_29 LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007482 268.0
HSJS3_k127_2960450_3 ABC transporter, urea K11959 - - 4.817e-245 760.0
HSJS3_k127_2960450_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002816 223.0
HSJS3_k127_2960450_31 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000226 231.0
HSJS3_k127_2960450_32 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000001037 219.0
HSJS3_k127_2960450_33 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000003934 206.0
HSJS3_k127_2960450_34 PhnA domain K06193 - - 0.00000000000000000000000000000000000000000000000000007256 190.0
HSJS3_k127_2960450_35 Glutathione-dependent formaldehyde-activating protein - - - 0.0000000000000000000000000000000000000000000000001544 179.0
HSJS3_k127_2960450_36 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000000000003155 177.0
HSJS3_k127_2960450_37 Domain of unknown function (DUF4124) - - - 0.0000000000000000000000000000000000000000000000003396 184.0
HSJS3_k127_2960450_38 Uncharacterised BCR, YnfA/UPF0060 family K09771 - - 0.0000000000000000000000000000000000000000000000004562 178.0
HSJS3_k127_2960450_39 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000004202 182.0
HSJS3_k127_2960450_4 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 - - 2.31e-231 739.0
HSJS3_k127_2960450_40 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.0000000000000000000000000000000000000000000002212 172.0
HSJS3_k127_2960450_41 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000195 165.0
HSJS3_k127_2960450_42 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000003972 118.0
HSJS3_k127_2960450_43 - - - - 0.0000000000000000000000006492 109.0
HSJS3_k127_2960450_44 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000001735 117.0
HSJS3_k127_2960450_45 Glutathione S-transferase K00799,K11209 - 2.5.1.18 0.000000000000000007257 83.0
HSJS3_k127_2960450_5 COG2203 FOG GAF domain K20962 - 3.1.4.52 9.026e-215 687.0
HSJS3_k127_2960450_6 Aminotransferase class-III K00836 - 2.6.1.76 1.361e-213 669.0
HSJS3_k127_2960450_7 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 1.36e-206 651.0
HSJS3_k127_2960450_8 Aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 5.43e-204 643.0
HSJS3_k127_2960450_9 Domain of unknown function (DUF4331) - - - 4.787e-201 638.0
HSJS3_k127_2979524_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1297.0
HSJS3_k127_2979524_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1140.0
HSJS3_k127_2979524_10 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 451.0
HSJS3_k127_2979524_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 442.0
HSJS3_k127_2979524_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 443.0
HSJS3_k127_2979524_13 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 438.0
HSJS3_k127_2979524_14 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 438.0
HSJS3_k127_2979524_15 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 430.0
HSJS3_k127_2979524_16 Protein of unknown function (DUF2817) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 406.0
HSJS3_k127_2979524_17 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 403.0
HSJS3_k127_2979524_18 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 401.0
HSJS3_k127_2979524_19 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 376.0
HSJS3_k127_2979524_2 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 1.452e-267 841.0
HSJS3_k127_2979524_20 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 376.0
HSJS3_k127_2979524_21 Nitronate monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 367.0
HSJS3_k127_2979524_22 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di-trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 362.0
HSJS3_k127_2979524_23 Glutathione S-transferase, C-terminal domain K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 341.0
HSJS3_k127_2979524_24 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 306.0
HSJS3_k127_2979524_25 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 284.0
HSJS3_k127_2979524_26 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003209 271.0
HSJS3_k127_2979524_27 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000218 253.0
HSJS3_k127_2979524_28 hydrolase of the alpha beta-hydrolase fold K07020 - - 0.0000000000000000000000000000000000000000000000000000000000000000001189 235.0
HSJS3_k127_2979524_29 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000005523 225.0
HSJS3_k127_2979524_3 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) - - - 3.734e-233 731.0
HSJS3_k127_2979524_30 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000008957 221.0
HSJS3_k127_2979524_31 Belongs to the ArsC family K00537 - 1.20.4.1 0.00000000000000000000000000000000000000000000002545 175.0
HSJS3_k127_2979524_32 protein conserved in bacteria - - - 0.00000000000000000000000000000000006782 139.0
HSJS3_k127_2979524_33 COG2825 Outer membrane protein K06142 - - 0.00000000000000000000000003328 114.0
HSJS3_k127_2979524_34 Thioesterase-like superfamily - - - 0.00000000000000000000000009663 123.0
HSJS3_k127_2979524_35 alpha beta - - - 0.0000000000000000000000001033 121.0
HSJS3_k127_2979524_37 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000001884 104.0
HSJS3_k127_2979524_38 Protein of unknown function (DUF2288) - - - 0.000000000000000000002403 96.0
HSJS3_k127_2979524_39 COG3540 Phosphodiesterase alkaline phosphatase D K01113 - 3.1.3.1 0.00000000000000000006927 93.0
HSJS3_k127_2979524_4 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 605.0
HSJS3_k127_2979524_40 Uncharacterized conserved protein (DUF2358) - - - 0.000000009501 66.0
HSJS3_k127_2979524_41 Belongs to the peptidase S8 family K14645 GO:0005575,GO:0005576 - 0.0000001411 64.0
HSJS3_k127_2979524_5 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005911 631.0
HSJS3_k127_2979524_6 Catalyzes the formation of succinyldiaminopimelate from N-succinyl-2-amino-6-ketopimelate K14267 - 2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000845 594.0
HSJS3_k127_2979524_7 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 583.0
HSJS3_k127_2979524_8 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 507.0
HSJS3_k127_2979524_9 energy transducer activity K03646,K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 531.0
HSJS3_k127_3003704_0 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 398.0
HSJS3_k127_3003704_1 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000003735 218.0
HSJS3_k127_3003704_2 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000003928 177.0
HSJS3_k127_3003704_3 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000006733 167.0
HSJS3_k127_3003704_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000006888 168.0
HSJS3_k127_3003704_5 META domain - - - 0.000000000000000000000009878 112.0
HSJS3_k127_3003704_6 - - - - 0.000000000000000000006415 106.0
HSJS3_k127_3003704_7 - - - - 0.0000000000000000001111 102.0
HSJS3_k127_306530_0 phosphate transporter K03306 - - 2.18e-199 630.0
HSJS3_k127_306530_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 530.0
HSJS3_k127_306530_2 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005243 420.0
HSJS3_k127_306530_3 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 333.0
HSJS3_k127_306530_4 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001346 268.0
HSJS3_k127_306530_5 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004961 261.0
HSJS3_k127_306530_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005562 226.0
HSJS3_k127_306530_7 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000002521 140.0
HSJS3_k127_306530_8 response to oxidative stress - - - 0.0000000000000000000000000000000002042 137.0
HSJS3_k127_306530_9 - - - - 0.0000000000002536 78.0
HSJS3_k127_3068108_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U16 in tRNAs K05541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 458.0
HSJS3_k127_3068108_1 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000304 269.0
HSJS3_k127_3068108_2 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.00000000000000000000000000000000000000000000000000000000000000007325 223.0
HSJS3_k127_3068108_3 thioesterase K07107 - - 0.0000000000000000000000000000000000001455 149.0
HSJS3_k127_3068108_4 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000002267 94.0
HSJS3_k127_3068108_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000004418 95.0
HSJS3_k127_3068671_0 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 347.0
HSJS3_k127_3068671_1 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 323.0
HSJS3_k127_3068671_2 - - - - 0.000000000000000000000000000001491 124.0
HSJS3_k127_3243211_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.845e-317 975.0
HSJS3_k127_3315814_0 Belongs to the BCCT transporter (TC 2.A.15) family K03451 - - 5.626e-268 832.0
HSJS3_k127_3315814_1 - - - - 2.149e-244 769.0
HSJS3_k127_3315814_10 membrane - - - 0.000000000000000000000000000000000000000000000000000001122 194.0
HSJS3_k127_3315814_11 COG2346 Truncated hemoglobins K06886 - - 0.000000000000000000000000000000000000000000007284 167.0
HSJS3_k127_3315814_2 homoserine dehydrogenase K00003 - 1.1.1.3 1.961e-219 688.0
HSJS3_k127_3315814_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 8.79e-212 661.0
HSJS3_k127_3315814_4 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 4.833e-209 655.0
HSJS3_k127_3315814_5 Belongs to the peptidase S1C family K04691,K04771,K04772 - 3.4.21.107 2.632e-200 632.0
HSJS3_k127_3315814_6 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 511.0
HSJS3_k127_3315814_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004672 507.0
HSJS3_k127_3315814_8 COG0436 Aspartate tyrosine aromatic aminotransferase K12252,K14261 - 2.6.1.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 346.0
HSJS3_k127_3315814_9 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000635 284.0
HSJS3_k127_3394968_0 in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 575.0
HSJS3_k127_3394968_1 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 461.0
HSJS3_k127_3394968_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 388.0
HSJS3_k127_3394968_3 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 344.0
HSJS3_k127_3394968_4 COG0517 FOG CBS domain - - - 0.0000000000000000000000000000000000000000000000005264 183.0
HSJS3_k127_3394968_5 heparin binding K03646 - - 0.0000000000000000000000000007939 117.0
HSJS3_k127_3432045_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1289.0
HSJS3_k127_3432045_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 1.421e-238 741.0
HSJS3_k127_3520216_0 Carbamoyl-phosphate synthetase glutamine chain K01956 GO:0000050,GO:0003674,GO:0003824,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0032991,GO:0034641,GO:0034654,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 1.959e-197 624.0
HSJS3_k127_3520216_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 401.0
HSJS3_k127_3520216_2 MafB19-like deaminase - - - 0.0000000000000000000000000000000000000000000000000003192 204.0
HSJS3_k127_3520216_3 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000000001987 81.0
HSJS3_k127_3533600_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 4.102e-240 754.0
HSJS3_k127_3533600_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003088 595.0
HSJS3_k127_3533600_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 530.0
HSJS3_k127_3533600_3 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 319.0
HSJS3_k127_3533600_4 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000000000000002425 119.0
HSJS3_k127_3533600_5 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000000179 76.0
HSJS3_k127_3533600_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000004469 69.0
HSJS3_k127_3632454_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 1.957e-271 843.0
HSJS3_k127_3632454_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 432.0
HSJS3_k127_3632454_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 409.0
HSJS3_k127_3632454_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000785 274.0
HSJS3_k127_3689854_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1472.0
HSJS3_k127_3689854_1 dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes - - - 0.0 1074.0
HSJS3_k127_3689854_10 COG2303 Choline dehydrogenase and related flavoproteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 479.0
HSJS3_k127_3689854_11 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K13775 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 464.0
HSJS3_k127_3689854_12 AraC family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 473.0
HSJS3_k127_3689854_13 ATPase, AAA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 450.0
HSJS3_k127_3689854_14 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 431.0
HSJS3_k127_3689854_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 362.0
HSJS3_k127_3689854_16 COG3552 Protein containing von Willebrand factor type A (vWA) domain K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 343.0
HSJS3_k127_3689854_17 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 332.0
HSJS3_k127_3689854_18 Dienelactone hydrolase and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 300.0
HSJS3_k127_3689854_19 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009498 270.0
HSJS3_k127_3689854_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.39e-306 956.0
HSJS3_k127_3689854_20 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000005569 260.0
HSJS3_k127_3689854_21 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009221 256.0
HSJS3_k127_3689854_22 hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000003062 232.0
HSJS3_k127_3689854_23 Predicted metal-dependent hydrolase K07044 - - 0.00000000000000000000000000000000000000000000000000000000000000002656 233.0
HSJS3_k127_3689854_24 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000004534 225.0
HSJS3_k127_3689854_26 transcriptional regulator K22105 - - 0.000000000000000000000000000000000000000000000000000000002473 206.0
HSJS3_k127_3689854_27 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000001064 204.0
HSJS3_k127_3689854_28 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases - - - 0.00000000000000000000000000000000000000000000000000002234 190.0
HSJS3_k127_3689854_29 Uncharacterized lipoprotein K07286 - - 0.00000000000000000000000000000000000000000000000001101 186.0
HSJS3_k127_3689854_3 Histidine kinase - - - 5.822e-242 773.0
HSJS3_k127_3689854_30 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K06718 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0018130,GO:0019491,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0042399,GO:0043170,GO:0043412,GO:0043436,GO:0043543,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.3.1.178 0.00000000000000000000000000000000000000000000000002864 183.0
HSJS3_k127_3689854_31 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000009606 178.0
HSJS3_k127_3689854_32 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000005834 157.0
HSJS3_k127_3689854_33 COG4966 Tfp pilus assembly protein PilW K02672 - - 0.00000000000000000000000000000000000000001853 163.0
HSJS3_k127_3689854_34 Antibiotic biosynthesis monooxygenase - GO:0003674,GO:0003824 - 0.0000000000000000000000000000000000000001604 157.0
HSJS3_k127_3689854_35 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000000002431 148.0
HSJS3_k127_3689854_36 Prokaryotic N-terminal methylation motif K02671 - - 0.00000000000000000000000000000000000434 143.0
HSJS3_k127_3689854_37 protein transport across the cell outer membrane K08084 - - 0.00000000000000000000000000000000005736 139.0
HSJS3_k127_3689854_39 - - - - 0.00000000000000000000000005248 113.0
HSJS3_k127_3689854_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 5.482e-236 739.0
HSJS3_k127_3689854_40 Pilus assembly protein PilX - - - 0.0000000000000000000000001414 113.0
HSJS3_k127_3689854_41 Cysteine-rich CPXCG - - - 0.0000000000000000000005437 96.0
HSJS3_k127_3689854_42 COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.00000000000000000002448 96.0
HSJS3_k127_3689854_43 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000003682 86.0
HSJS3_k127_3689854_45 Bacterial regulatory proteins, tetR family - - - 0.000001518 58.0
HSJS3_k127_3689854_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 8.427e-196 616.0
HSJS3_k127_3689854_6 unusual protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 558.0
HSJS3_k127_3689854_7 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 531.0
HSJS3_k127_3689854_8 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 529.0
HSJS3_k127_3689854_9 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 483.0
HSJS3_k127_3772961_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1482.0
HSJS3_k127_3772961_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 593.0
HSJS3_k127_3772961_2 Ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000000001644 219.0
HSJS3_k127_3772961_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000007475 109.0
HSJS3_k127_3843002_0 Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair K03580 - - 0.0 1191.0
HSJS3_k127_3843002_1 Molecular chaperone. Has ATPase activity K04079 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006950,GO:0006974,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042623,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716 - 1.489e-265 831.0
HSJS3_k127_3843002_10 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001184 282.0
HSJS3_k127_3843002_11 Carboxylesterase K06999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002879 272.0
HSJS3_k127_3843002_12 COG0625 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000008597 259.0
HSJS3_k127_3843002_13 EAL domain - GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008081,GO:0008150,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0016020,GO:0016021,GO:0016787,GO:0016788,GO:0031224,GO:0033554,GO:0034059,GO:0034599,GO:0034614,GO:0035690,GO:0036293,GO:0036294,GO:0042221,GO:0042493,GO:0042542,GO:0042578,GO:0043900,GO:0044425,GO:0044464,GO:0046677,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070301,GO:0070482,GO:0070887,GO:0071111,GO:0071236,GO:0071453,GO:0071454,GO:0071944,GO:0097237,GO:1900190,GO:1901700,GO:1901701 - 0.0000000000000000000000000000000000000000000000000000000000000001641 246.0
HSJS3_k127_3843002_14 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000007436 214.0
HSJS3_k127_3843002_15 - - - - 0.0000000000000000000000000000000000000000000000000000001311 199.0
HSJS3_k127_3843002_16 - - - - 0.0000000000000000000000000000000000000000000000201 179.0
HSJS3_k127_3843002_17 - - - - 0.00000000000000000000008225 102.0
HSJS3_k127_3843002_18 - - - - 0.000000000000000001925 88.0
HSJS3_k127_3843002_19 OmpA-like transmembrane domain - - - 0.0000009586 58.0
HSJS3_k127_3843002_2 Tetratricopeptide repeat - - - 2.055e-261 818.0
HSJS3_k127_3843002_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.784e-203 646.0
HSJS3_k127_3843002_4 Domain of unknown function (DUF4397) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 514.0
HSJS3_k127_3843002_5 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 441.0
HSJS3_k127_3843002_6 COG0412 Dienelactone hydrolase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 320.0
HSJS3_k127_3843002_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 327.0
HSJS3_k127_3843002_8 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 307.0
HSJS3_k127_3843002_9 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 297.0
HSJS3_k127_3903681_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 557.0
HSJS3_k127_3903681_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 502.0
HSJS3_k127_3903681_2 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 376.0
HSJS3_k127_391964_0 Vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0 1750.0
HSJS3_k127_391964_1 unusual protein kinase - - - 3.051e-238 745.0
HSJS3_k127_391964_10 COG3288 NAD NADP transhydrogenase alpha subunit K00324 - 1.6.1.2 0.000000000000000000000000000000000002522 139.0
HSJS3_k127_391964_11 - - - - 0.00000000000000000000000001507 115.0
HSJS3_k127_391964_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 8.969e-199 627.0
HSJS3_k127_391964_3 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 514.0
HSJS3_k127_391964_4 kinase activity K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 471.0
HSJS3_k127_391964_5 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 400.0
HSJS3_k127_391964_6 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 328.0
HSJS3_k127_391964_7 Salt-induced outer membrane protein K07283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 304.0
HSJS3_k127_391964_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 296.0
HSJS3_k127_391964_9 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000004428 204.0
HSJS3_k127_4022825_0 LVIVD repeat - - - 0.0 1772.0
HSJS3_k127_4022825_1 4Fe-4S dicluster domain - - - 2.173e-282 888.0
HSJS3_k127_4022825_10 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 289.0
HSJS3_k127_4022825_11 ATPase, AAA K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001885 253.0
HSJS3_k127_4022825_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002081 251.0
HSJS3_k127_4022825_13 Acyl-ACP thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000003917 205.0
HSJS3_k127_4022825_14 Thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000006889 184.0
HSJS3_k127_4022825_15 - - - - 0.0000000000000000000000000000000000000000000001053 183.0
HSJS3_k127_4022825_16 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.00000000267 57.0
HSJS3_k127_4022825_2 - - - - 5.601e-207 660.0
HSJS3_k127_4022825_3 Haem-degrading - - - 1.569e-198 638.0
HSJS3_k127_4022825_4 COG1454 Alcohol dehydrogenase, class IV K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 455.0
HSJS3_k127_4022825_5 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 434.0
HSJS3_k127_4022825_6 with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 332.0
HSJS3_k127_4022825_7 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 334.0
HSJS3_k127_4022825_8 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 307.0
HSJS3_k127_4022825_9 Protein of unknown function (DUF1524) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 294.0
HSJS3_k127_4034214_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1076.0
HSJS3_k127_4034214_1 ABC transporter K06147,K11085 - - 2.061e-234 740.0
HSJS3_k127_4034214_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 501.0
HSJS3_k127_4034214_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
HSJS3_k127_4034214_4 - - - - 0.000000000000000000000000000000000000000000000000001993 195.0
HSJS3_k127_4034214_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000001761 179.0
HSJS3_k127_4034214_6 Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA K00219 - 1.3.1.34 0.00000000000000000003145 91.0
HSJS3_k127_4034214_7 surface antigen - - - 0.00000001406 65.0
HSJS3_k127_4040639_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1462.0
HSJS3_k127_4040639_1 accessory protein K06959 - - 0.0 1124.0
HSJS3_k127_4040639_2 NADH dehydrogenase K03885 - 1.6.99.3 2.464e-209 660.0
HSJS3_k127_4040639_3 Histidine kinase K07638 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 576.0
HSJS3_k127_4040639_4 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 414.0
HSJS3_k127_4040639_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 410.0
HSJS3_k127_4040639_6 COG0845 Membrane-fusion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006536 363.0
HSJS3_k127_4040639_8 COG0784 FOG CheY-like receiver K02658 - - 0.00000000000000000000000000000000000000000000000000000000005787 206.0
HSJS3_k127_4040639_9 repeat protein - - - 0.0000000007588 71.0
HSJS3_k127_4064271_0 ABC transporter ATP-binding protein - - - 0.0 1001.0
HSJS3_k127_4064271_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.058e-234 736.0
HSJS3_k127_4064271_10 Riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 340.0
HSJS3_k127_4064271_11 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 290.0
HSJS3_k127_4064271_12 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000535 280.0
HSJS3_k127_4064271_13 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001191 261.0
HSJS3_k127_4064271_14 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005256 254.0
HSJS3_k127_4064271_15 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000001405 244.0
HSJS3_k127_4064271_16 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000000000002164 221.0
HSJS3_k127_4064271_17 Binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000244 223.0
HSJS3_k127_4064271_18 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000001795 224.0
HSJS3_k127_4064271_19 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000004859 208.0
HSJS3_k127_4064271_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.174e-232 724.0
HSJS3_k127_4064271_20 3D domain protein - - - 0.00000000000000000000000000000000000000000000001577 176.0
HSJS3_k127_4064271_21 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000000000000000000007295 148.0
HSJS3_k127_4064271_23 DNA replication, synthesis of RNA primer K02686 GO:0000228,GO:0000428,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005657,GO:0005658,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006270,GO:0006276,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0016070,GO:0018130,GO:0019438,GO:0030880,GO:0030894,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043565,GO:0043596,GO:0043601,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0055029,GO:0061695,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990077,GO:1990099,GO:1990234,GO:1990837 - 0.0000000000000000000000000000008753 126.0
HSJS3_k127_4064271_24 phosphorelay signal transduction system - - - 0.000000000000000000000000006797 115.0
HSJS3_k127_4064271_26 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.000000000000001832 80.0
HSJS3_k127_4064271_28 - - - - 0.0000000005323 64.0
HSJS3_k127_4064271_3 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 1.246e-229 715.0
HSJS3_k127_4064271_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.139e-223 698.0
HSJS3_k127_4064271_5 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 570.0
HSJS3_k127_4064271_6 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 551.0
HSJS3_k127_4064271_7 esterase of the alpha-beta hydrolase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003633 514.0
HSJS3_k127_4064271_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 479.0
HSJS3_k127_4064271_9 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 419.0
HSJS3_k127_4089422_0 acyl-CoA dehydrogenase K09456 - - 1.571e-260 817.0
HSJS3_k127_4089422_1 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 467.0
HSJS3_k127_4089422_2 Protein involved in plasmid maintenance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 413.0
HSJS3_k127_4089422_3 COG1192 ATPases involved in chromosome partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 406.0
HSJS3_k127_4089422_4 Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons K01563 - 3.8.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 348.0
HSJS3_k127_4089422_5 COG1309 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000002299 198.0
HSJS3_k127_4089422_6 COG1309 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001852 176.0
HSJS3_k127_4089422_7 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000106 136.0
HSJS3_k127_4089422_8 methyltransferase K16868 - 2.1.1.265 0.00004389 46.0
HSJS3_k127_4090044_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 362.0
HSJS3_k127_4090044_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 367.0
HSJS3_k127_4090044_2 ATPase, AAA K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 291.0
HSJS3_k127_4090044_3 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001245 283.0
HSJS3_k127_4090044_4 membrane protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000003604 221.0
HSJS3_k127_4090044_5 membrane - - - 0.000000000000000968 82.0
HSJS3_k127_4090044_6 Domain of unknown function (DUF4350) - - - 0.0001735 54.0
HSJS3_k127_4092559_0 type II secretion system protein K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 576.0
HSJS3_k127_4092559_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 390.0
HSJS3_k127_4092559_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000001255 235.0
HSJS3_k127_4273485_0 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 1.199e-242 752.0
HSJS3_k127_4273485_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 358.0
HSJS3_k127_4273485_2 COG0695 Glutaredoxin and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000578 337.0
HSJS3_k127_4273485_3 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006292 287.0
HSJS3_k127_4273485_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000000000003772 235.0
HSJS3_k127_4273485_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000002799 60.0
HSJS3_k127_4346868_0 Histidine kinase - - - 0.0 1616.0
HSJS3_k127_4346868_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 1.065e-245 766.0
HSJS3_k127_4346868_10 kinase activity K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004315 303.0
HSJS3_k127_4346868_11 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000373 277.0
HSJS3_k127_4346868_12 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001154 254.0
HSJS3_k127_4346868_13 Protein of unknown function (DUF1461) - - - 0.0000000000000000000000000000000000000000000000000000000000000006118 228.0
HSJS3_k127_4346868_14 Protein-glutamate methylesterase K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000004285 216.0
HSJS3_k127_4346868_15 general secretion pathway protein K02459 - - 0.00000000000000000000000000000000000000000000000000000000002119 212.0
HSJS3_k127_4346868_16 secretion system protein G K02456 - - 0.00000000000000000000000000000000000000000000000004183 182.0
HSJS3_k127_4346868_17 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.000000000000000000000000000000000000000000000001999 188.0
HSJS3_k127_4346868_18 Type II secretion system (T2SS), protein I K02458 - - 0.0000000000000000000000000000000000003705 143.0
HSJS3_k127_4346868_19 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02462 - - 0.00000000000000000000000000001543 125.0
HSJS3_k127_4346868_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.391e-236 747.0
HSJS3_k127_4346868_20 Prokaryotic N-terminal methylation motif K02457 - - 0.000000000000000000000003489 110.0
HSJS3_k127_4346868_22 Resolvase, N terminal domain - - - 0.00000001459 61.0
HSJS3_k127_4346868_23 L,D-transpeptidase catalytic domain - - - 0.00000005197 55.0
HSJS3_k127_4346868_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 4.566e-206 654.0
HSJS3_k127_4346868_4 general secretion pathway protein K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000355 494.0
HSJS3_k127_4346868_5 chemotaxis K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 465.0
HSJS3_k127_4346868_6 Sensory box protein response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 469.0
HSJS3_k127_4346868_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 394.0
HSJS3_k127_4346868_8 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 349.0
HSJS3_k127_4346868_9 COG3156 Type II secretory pathway, component PulK K02460 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 320.0
HSJS3_k127_4388066_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 7.181e-295 908.0
HSJS3_k127_4388066_1 membrane K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 500.0
HSJS3_k127_4388066_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 392.0
HSJS3_k127_4388066_3 RDD family - - - 0.0000000000000000000000000000000000000000000001834 173.0
HSJS3_k127_4388066_4 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000005942 98.0
HSJS3_k127_4388066_5 arsenate reductase K00537 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.20.4.1 0.0000000000001187 71.0
HSJS3_k127_4392803_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 547.0
HSJS3_k127_4392803_1 Phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 429.0
HSJS3_k127_4392803_2 transporter K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 430.0
HSJS3_k127_4392803_3 DUF218 domain - - - 0.00000000000000000000000000000000000000000000002987 178.0
HSJS3_k127_4392803_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000000002861 168.0
HSJS3_k127_4392803_5 proteolysis K19225 - 3.4.21.105 0.0000000000000000000000000000000000002544 158.0
HSJS3_k127_4392803_6 competence protein - - - 0.0000000000000000000000000000000000003671 157.0
HSJS3_k127_4406357_0 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000002432 183.0
HSJS3_k127_4406357_1 Polysaccharide biosynthesis protein - - - 0.00000000004162 69.0
HSJS3_k127_4406357_2 DnaJ molecular chaperone homology domain - - - 0.000000131 54.0
HSJS3_k127_4484346_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.698e-201 634.0
HSJS3_k127_4484346_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 486.0
HSJS3_k127_4484346_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 371.0
HSJS3_k127_4484346_3 acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 304.0
HSJS3_k127_4484346_4 acetolactate synthase K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 295.0
HSJS3_k127_4484346_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000004758 217.0
HSJS3_k127_4509451_0 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0 1070.0
HSJS3_k127_4509451_1 Histidine kinase - - - 5.48e-300 941.0
HSJS3_k127_4509451_2 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 6.282e-256 810.0
HSJS3_k127_4509451_3 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 3.197e-236 733.0
HSJS3_k127_4509451_4 COG0714 MoxR-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 439.0
HSJS3_k127_4509451_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 344.0
HSJS3_k127_4509451_6 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
HSJS3_k127_4509451_7 Evidence 4 Homologs of previously reported genes of K09700 - - 0.0000000000000000000000000000000000000000000000001676 177.0
HSJS3_k127_4509451_8 cytochrome c5 - - - 0.0000000000000000000000000000000000000000000001996 173.0
HSJS3_k127_4543351_0 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 364.0
HSJS3_k127_4543351_1 aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009697 260.0
HSJS3_k127_4543351_2 Protein of unknown function (DUF1285) K09986 - - 0.00000000000000000000000000000000000000000002354 168.0
HSJS3_k127_454729_0 ABC-type oligopeptide transport system, periplasmic component K13893 - - 9.566e-242 764.0
HSJS3_k127_454729_1 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 3.398e-216 684.0
HSJS3_k127_454729_2 Belongs to the ABC transporter superfamily K13896 - - 1.036e-210 666.0
HSJS3_k127_454729_3 COG4166 ABC-type oligopeptide transport system, periplasmic component K13893 - - 7.688e-196 628.0
HSJS3_k127_454729_4 ABC transporter permease K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002783 563.0
HSJS3_k127_454729_5 With YejAEF is involved in resistance to microcin C K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 561.0
HSJS3_k127_454729_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 452.0
HSJS3_k127_454729_7 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000002348 149.0
HSJS3_k127_4556347_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1027.0
HSJS3_k127_4556347_1 protein related to deoxyribodipyrimidine photolyase K06876 - - 2.496e-245 766.0
HSJS3_k127_4556347_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000000002251 224.0
HSJS3_k127_4556347_11 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000269 224.0
HSJS3_k127_4556347_12 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000000000001042 189.0
HSJS3_k127_4556347_13 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.000000000000000000000000000000000000000000000000004922 191.0
HSJS3_k127_4556347_14 Domain of unknown function (DUF4399) - - - 0.0000000000000000000000000000000000000000000000004479 180.0
HSJS3_k127_4556347_15 protein conserved in bacteria - - - 0.0000000000000007036 79.0
HSJS3_k127_4556347_2 thymidine phosphorylase K00758 - 2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 544.0
HSJS3_k127_4556347_3 DEAD-box RNA helicase involved in - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 385.0
HSJS3_k127_4556347_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 345.0
HSJS3_k127_4556347_5 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 339.0
HSJS3_k127_4556347_6 N-terminal domain of ribose phosphate pyrophosphokinase K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006601 296.0
HSJS3_k127_4556347_7 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001151 272.0
HSJS3_k127_4556347_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000001008 253.0
HSJS3_k127_4556347_9 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007636 259.0
HSJS3_k127_4593183_0 transport system, large permease component - - - 1.407e-207 652.0
HSJS3_k127_4593183_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 291.0
HSJS3_k127_4649003_0 COG0515 Serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 434.0
HSJS3_k127_4649003_1 Preprotein translocase subunit SecA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001145 262.0
HSJS3_k127_4649003_2 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.0000000000000000000000000000000000000000000000000000001564 199.0
HSJS3_k127_4649003_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000001556 55.0
HSJS3_k127_4672276_0 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 4.53e-293 901.0
HSJS3_k127_4672276_1 COG1960 Acyl-CoA dehydrogenases - - - 3.225e-232 721.0
HSJS3_k127_4672276_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.349e-209 655.0
HSJS3_k127_4672276_3 Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate K00265 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 569.0
HSJS3_k127_4672276_4 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 367.0
HSJS3_k127_4672276_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 318.0
HSJS3_k127_4672276_6 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006466 235.0
HSJS3_k127_4672276_7 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000299 209.0
HSJS3_k127_4672276_8 FlgJ-related protein K03796 - - 0.000000000000000000000000000000000000000000000001097 184.0
HSJS3_k127_4672276_9 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000000000001033 167.0
HSJS3_k127_4848453_0 protein involved in outer membrane biogenesis K07289 - - 2.46e-240 764.0
HSJS3_k127_4848453_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 607.0
HSJS3_k127_4848453_10 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000003306 151.0
HSJS3_k127_4848453_11 S4 RNA-binding domain K04762 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009451,GO:0009628,GO:0009987,GO:0016070,GO:0033554,GO:0034605,GO:0034641,GO:0043021,GO:0043023,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000007972 139.0
HSJS3_k127_4848453_13 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.0000000001602 61.0
HSJS3_k127_4848453_14 - - - - 0.0000004084 53.0
HSJS3_k127_4848453_15 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0001485 45.0
HSJS3_k127_4848453_2 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 583.0
HSJS3_k127_4848453_3 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 451.0
HSJS3_k127_4848453_4 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 396.0
HSJS3_k127_4848453_5 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 368.0
HSJS3_k127_4848453_6 nucleotidase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 350.0
HSJS3_k127_4848453_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 320.0
HSJS3_k127_4848453_8 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K08312 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009218 304.0
HSJS3_k127_4848453_9 hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 303.0
HSJS3_k127_492943_0 COG0277 FAD FMN-containing dehydrogenases K00803 - 2.5.1.26 1.778e-279 865.0
HSJS3_k127_492943_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - - - 4.015e-265 829.0
HSJS3_k127_492943_10 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000002045 145.0
HSJS3_k127_492943_11 MgtC family K07507 - - 0.000000000000000000000000000000009568 130.0
HSJS3_k127_492943_12 Transposase IS200 like - - - 0.00000001402 57.0
HSJS3_k127_492943_2 COG2355 Zn-dependent dipeptidase, microsomal dipeptidase homolog - - - 3.256e-247 782.0
HSJS3_k127_492943_3 Carbohydrate kinase K00854,K00862 - 2.7.1.17,2.7.1.215 8.388e-246 768.0
HSJS3_k127_492943_4 Glycerol-3-phosphate dehydrogenase K00111,K21054 - 1.1.1.402,1.1.5.3 6.327e-204 646.0
HSJS3_k127_492943_5 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 412.0
HSJS3_k127_492943_6 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 374.0
HSJS3_k127_492943_7 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 319.0
HSJS3_k127_492943_8 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000005448 174.0
HSJS3_k127_492943_9 Transcriptional - - - 0.00000000000000000000000000000000000000000006691 165.0
HSJS3_k127_4994458_0 belongs to the carbohydrate kinase PfkB family K00847,K00892 - 2.7.1.4,2.7.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009547 451.0
HSJS3_k127_4994458_1 Aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 443.0
HSJS3_k127_4994458_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 409.0
HSJS3_k127_4994458_3 Belongs to the SfsA family K06206 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 320.0
HSJS3_k127_4994458_4 Rieske 2Fe-2S - - - 0.000000000000000000000000000000000000000000006715 172.0
HSJS3_k127_5084_0 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 422.0
HSJS3_k127_5084_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134,K03472 - 1.2.1.12,1.2.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 419.0
HSJS3_k127_5084_10 Bacterial protein of unknown function (DUF883) - - - 0.000000002443 63.0
HSJS3_k127_5084_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 369.0
HSJS3_k127_5084_3 membrane protein, hemolysin III homolog K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 342.0
HSJS3_k127_5084_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 362.0
HSJS3_k127_5084_5 Ferritin-like domain K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0020037,GO:0030003,GO:0042592,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0097159,GO:0097577,GO:0098771,GO:1901363 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008792 268.0
HSJS3_k127_5084_6 - - - - 0.00000000000000000000000000000000000000000000000000000002894 207.0
HSJS3_k127_5084_7 - - - - 0.000000000000000000000000000000000000000001547 164.0
HSJS3_k127_5084_8 - - - - 0.00000000000000000000000000001921 127.0
HSJS3_k127_5084_9 Bacterioferritin-associated ferredoxin K02192 - - 0.000000000000001703 84.0
HSJS3_k127_5398264_0 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 519.0
HSJS3_k127_5398264_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 516.0
HSJS3_k127_5398264_10 amino acid transport K02030 - - 0.0000000000000000000000000000000000000000001392 168.0
HSJS3_k127_5398264_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000001398 123.0
HSJS3_k127_5398264_12 Catalyzes the circularization of gamma-N-acetyl- alpha,gamma-diaminobutyric acid (ADABA) to ectoine (1,4,5,6- tetrahydro-2-methyl-4-pyrimidine carboxylic acid), which is an excellent osmoprotectant K06720 - 4.2.1.108 0.000000000000682 68.0
HSJS3_k127_5398264_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 494.0
HSJS3_k127_5398264_3 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 374.0
HSJS3_k127_5398264_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 366.0
HSJS3_k127_5398264_5 ABC-type metal ion transport system, periplasmic component surface adhesin K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 311.0
HSJS3_k127_5398264_6 COG1846 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 245.0
HSJS3_k127_5398264_7 L-2,4-diaminobutyric acid acetyltransferase K06718 - 2.3.1.178 0.000000000000000000000000000000000000000000000000000000000000000000003958 241.0
HSJS3_k127_5398264_8 ABC 3 transport family K02075 - - 0.00000000000000000000000000000000000000000000000000000000000008914 221.0
HSJS3_k127_5398264_9 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000000000000000000000000000002964 207.0
HSJS3_k127_539854_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 5.796e-248 770.0
HSJS3_k127_539854_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.444e-237 737.0
HSJS3_k127_539854_2 Belongs to the KdsA family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 476.0
HSJS3_k127_539854_3 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 400.0
HSJS3_k127_539854_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 342.0
HSJS3_k127_539854_5 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005442 283.0
HSJS3_k127_539854_6 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003097 282.0
HSJS3_k127_539854_7 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000007086 234.0
HSJS3_k127_539854_8 membrane K08974 - - 0.0000000000000000000000000000000000000000000000000000000000000000001032 236.0
HSJS3_k127_539854_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000000001965 128.0
HSJS3_k127_5425412_0 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 482.0
HSJS3_k127_5425412_1 Dystroglycan-type cadherin-like domains. - - - 0.0000000000000002175 94.0
HSJS3_k127_5425412_2 Regulator of chromosome condensation (RCC1) repeat - - - 0.0000002187 64.0
HSJS3_k127_5425412_3 glucose sorbosone - - - 0.000002624 61.0
HSJS3_k127_5431474_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044262,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046487,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 2.465e-313 981.0
HSJS3_k127_5431474_1 COG1960 Acyl-CoA dehydrogenases K00248 - 1.3.8.1 3.662e-221 702.0
HSJS3_k127_5431474_10 COG2755 Lysophospholipase L1 and related esterases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005282 271.0
HSJS3_k127_5431474_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000001869 222.0
HSJS3_k127_5431474_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000003137 204.0
HSJS3_k127_5431474_13 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000001732 180.0
HSJS3_k127_5431474_14 transcriptional regulator - - - 0.000000000000000000000000000000008353 136.0
HSJS3_k127_5431474_2 Domain of unknown function (DUF3520) K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 567.0
HSJS3_k127_5431474_3 unusual protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 552.0
HSJS3_k127_5431474_4 NmrA-like family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 452.0
HSJS3_k127_5431474_5 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004566 401.0
HSJS3_k127_5431474_6 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 391.0
HSJS3_k127_5431474_7 Enoyl-CoA hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 373.0
HSJS3_k127_5431474_8 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 349.0
HSJS3_k127_5431474_9 Domain of unknown function (DUF4382) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 302.0
HSJS3_k127_5432744_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1162.0
HSJS3_k127_5432744_1 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 557.0
HSJS3_k127_5432744_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 320.0
HSJS3_k127_5432744_11 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002747 292.0
HSJS3_k127_5432744_12 fatty acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001847 248.0
HSJS3_k127_5432744_13 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001688 198.0
HSJS3_k127_5432744_14 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000000000000000000000000000000000007211 184.0
HSJS3_k127_5432744_15 Trypsin-like serine protease - - - 0.000000000000000000000000000000000000000000000002458 194.0
HSJS3_k127_5432744_16 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000002088 160.0
HSJS3_k127_5432744_17 Chalcone isomerase-like - - - 0.00000000000000000000000000000000005152 140.0
HSJS3_k127_5432744_18 Gaf domain - - - 0.0000000000000000000000000000000001157 144.0
HSJS3_k127_5432744_19 Ketosteroid isomerase-related protein - - - 0.0000000000000000000000000000000004545 139.0
HSJS3_k127_5432744_2 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 506.0
HSJS3_k127_5432744_20 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000001179 130.0
HSJS3_k127_5432744_21 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000001346 127.0
HSJS3_k127_5432744_22 - - - - 0.00000000000000000000000002606 112.0
HSJS3_k127_5432744_23 PilZ domain - - - 0.000000000000002679 81.0
HSJS3_k127_5432744_24 protein conserved in bacteria - - - 0.0000000000008812 69.0
HSJS3_k127_5432744_25 Protein of unknown function (DUF1631) - - - 0.00000000187 70.0
HSJS3_k127_5432744_3 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008979 467.0
HSJS3_k127_5432744_4 Cyclopropane fatty acid synthase and related K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 453.0
HSJS3_k127_5432744_5 Flavodoxin reductases (Ferredoxin-NADPH reductases) family 1 K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 396.0
HSJS3_k127_5432744_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 381.0
HSJS3_k127_5432744_7 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006101 358.0
HSJS3_k127_5432744_8 Histidine-specific methyltransferase, SAM-dependent K18911 - 2.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 346.0
HSJS3_k127_5432744_9 D-alanine [D-alanyl carrier protein] ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 327.0
HSJS3_k127_5636219_0 acetyl-CoA hydrolase - - - 1.592e-254 803.0
HSJS3_k127_5636219_1 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 300.0
HSJS3_k127_5636219_2 Domain of unknown function (DUF4282) - - - 0.0000000000000000000000000000000000000000000000000000002843 201.0
HSJS3_k127_5636219_3 Protein of unknown function (DUF2804) - - - 0.0000000007877 64.0
HSJS3_k127_5643477_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1063.0
HSJS3_k127_5643477_1 can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli K11105 - - 3.237e-223 704.0
HSJS3_k127_5643477_2 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 549.0
HSJS3_k127_5643477_3 Iron permease FTR1 family K07243 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003947 499.0
HSJS3_k127_5643477_4 Chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 466.0
HSJS3_k127_5643477_5 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 448.0
HSJS3_k127_5643477_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 418.0
HSJS3_k127_5643477_7 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000691 240.0
HSJS3_k127_5643477_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000007193 83.0
HSJS3_k127_5694141_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 417.0
HSJS3_k127_5694141_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000003254 158.0
HSJS3_k127_5704314_0 COG1233 Phytoene dehydrogenase and related proteins K09516 - 1.3.99.23 3.564e-256 801.0
HSJS3_k127_5704314_1 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 7.924e-239 742.0
HSJS3_k127_5704314_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000001466 180.0
HSJS3_k127_5704314_11 protein conserved in bacteria K09908 - - 0.00000000000000000000000000000000000000000002919 170.0
HSJS3_k127_5704314_12 WHG domain - - - 0.000000000000000000000000000000000004556 145.0
HSJS3_k127_5704314_13 CAAX protease self-immunity - - - 0.000003684 59.0
HSJS3_k127_5704314_14 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0009163 43.0
HSJS3_k127_5704314_2 COG1960 Acyl-CoA dehydrogenases K00249 - 1.3.8.7 3.316e-222 694.0
HSJS3_k127_5704314_3 COG3670 Lignostilbene-alpha,beta-dioxygenase and related enzymes K00464 - 1.13.11.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 587.0
HSJS3_k127_5704314_4 Reduces the stability of FtsZ polymers in the presence of ATP K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 559.0
HSJS3_k127_5704314_5 Aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 547.0
HSJS3_k127_5704314_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 325.0
HSJS3_k127_5704314_7 hydrolase of the alpha beta superfamily K07018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002665 255.0
HSJS3_k127_5704314_8 chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000817 175.0
HSJS3_k127_5704314_9 Virulence activator alpha C-term - - - 0.00000000000000000000000000000000000000000000001173 177.0
HSJS3_k127_5721942_0 COG2267 Lysophospholipase K01048 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 441.0
HSJS3_k127_5721942_1 COG3417 Collagen-binding surface adhesin SpaP (antigen I II family) K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005275 317.0
HSJS3_k127_5721942_2 Curli production assembly/transport component CsgG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 323.0
HSJS3_k127_5721942_3 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007309 275.0
HSJS3_k127_5721942_4 Protein of unknown function (DUF1425) - - - 0.00000000000000000000000000000000000000000000003789 173.0
HSJS3_k127_5721942_5 - - - - 0.0000000000000000000001289 108.0
HSJS3_k127_5721942_6 Flavin reductase like domain - - - 0.0000001166 54.0
HSJS3_k127_5725430_0 Belongs to the AAA ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 493.0
HSJS3_k127_5725430_1 Metal-dependent hydrolase K07044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000441 338.0
HSJS3_k127_5725430_2 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 294.0
HSJS3_k127_5725430_3 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000006854 201.0
HSJS3_k127_5725430_4 - - - - 0.00003853 52.0
HSJS3_k127_5759416_0 exonuclease recJ K07462 - - 2.188e-226 717.0
HSJS3_k127_577511_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1621.0
HSJS3_k127_577511_1 membrane - - - 1.145e-269 874.0
HSJS3_k127_577511_10 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 344.0
HSJS3_k127_577511_11 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 331.0
HSJS3_k127_577511_12 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 317.0
HSJS3_k127_577511_13 transcriptional regulator K13770 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001423 269.0
HSJS3_k127_577511_14 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001293 237.0
HSJS3_k127_577511_15 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K11890,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000005506 221.0
HSJS3_k127_577511_16 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000003462 203.0
HSJS3_k127_577511_17 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 - - 0.0000000000000000000000000000000000000000000000007322 181.0
HSJS3_k127_577511_18 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000000106 172.0
HSJS3_k127_577511_19 Carbon-nitrogen hydrolase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000193 155.0
HSJS3_k127_577511_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.824e-238 744.0
HSJS3_k127_577511_20 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000001919 142.0
HSJS3_k127_577511_21 DNA polymerase III chi subunit K02339 - 2.7.7.7 0.000000000000000000000000000000000002472 145.0
HSJS3_k127_577511_22 membrane - - - 0.0000000000000000000001166 100.0
HSJS3_k127_577511_3 Responsible for the proteolytic maturation of the E. coli pMccB17 plasmid-encoded microcin B17, an exported protein that targets the essential topoisomerase II DNA gyrase K03568 - - 3.17e-233 730.0
HSJS3_k127_577511_4 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 7.397e-231 722.0
HSJS3_k127_577511_5 Rod shape-determining protein K03569 - - 3.096e-199 631.0
HSJS3_k127_577511_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 2.526e-198 630.0
HSJS3_k127_577511_7 permease K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 486.0
HSJS3_k127_577511_8 Permease K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 398.0
HSJS3_k127_577511_9 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 368.0
HSJS3_k127_5781137_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.059e-215 676.0
HSJS3_k127_5781137_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 605.0
HSJS3_k127_5781137_2 glycosyl transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 329.0
HSJS3_k127_5781137_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000003103 85.0
HSJS3_k127_5817717_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1212.0
HSJS3_k127_5817717_1 COG1960 Acyl-CoA dehydrogenases - - - 6.864e-229 712.0
HSJS3_k127_5817717_10 protein conserved in bacteria K09931 - - 0.000000000000000000000000233 117.0
HSJS3_k127_5817717_11 FOG HPt domain K20976 - - 0.000000000000000000000406 99.0
HSJS3_k127_5817717_2 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 577.0
HSJS3_k127_5817717_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 348.0
HSJS3_k127_5817717_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 312.0
HSJS3_k127_5817717_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 287.0
HSJS3_k127_5817717_6 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001473 245.0
HSJS3_k127_5817717_7 energy transducer activity K03646,K03832 - - 0.00000000000000000000000000000000000000000000000000000000000003125 239.0
HSJS3_k127_5817717_8 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000000000000001261 213.0
HSJS3_k127_5817717_9 Fe-S oxidoreductases - - - 0.000000000000000000000000000000000000000000000001581 175.0
HSJS3_k127_5915344_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 493.0
HSJS3_k127_5915344_1 signal transduction protein with a C-terminal ATPase domain K08082 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 452.0
HSJS3_k127_5915344_2 Response regulator of the LytR AlgR family K02477,K08083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 363.0
HSJS3_k127_5915344_3 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008561 358.0
HSJS3_k127_5915344_4 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000005342 192.0
HSJS3_k127_5915344_5 synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000006731 166.0
HSJS3_k127_5915344_6 TRL-like protein family - - - 0.0000000000000000000000000000000000000006323 150.0
HSJS3_k127_5996807_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.0 1450.0
HSJS3_k127_5996807_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 8.395e-198 631.0
HSJS3_k127_5996807_2 alanine symporter K03310 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006726 588.0
HSJS3_k127_5996807_3 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000789 319.0
HSJS3_k127_5996807_4 COG3023 Negative regulator of beta-lactamase expression K01447,K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043170,GO:0044424,GO:0044464,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000003243 254.0
HSJS3_k127_5996807_5 adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000002767 211.0
HSJS3_k127_5996807_6 Membrane protein required for beta-lactamase induction K03807 - - 0.000000000000000000000000000000000000000000000000000001506 202.0
HSJS3_k127_5996807_7 Belongs to the N-Me-Phe pilin family K02650 - - 0.000000000000000000000000000001614 127.0
HSJS3_k127_5996807_8 TonB-dependent Receptor Plug K02014 - - 0.00000000000004984 74.0
HSJS3_k127_6029356_0 belongs to the aldehyde dehydrogenase family K00154 - 1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 552.0
HSJS3_k127_6029356_1 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 287.0
HSJS3_k127_6029419_0 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 441.0
HSJS3_k127_6029419_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000001117 211.0
HSJS3_k127_6029419_2 - - - - 0.000000000000000000000000000000000000000000000000001472 187.0
HSJS3_k127_6029419_3 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.0000000000000000000000000000000000000000003671 165.0
HSJS3_k127_6029419_4 Domain of unknown function (DUF1772) - - - 0.00000000000000000000000000000007895 130.0
HSJS3_k127_6029419_5 protein conserved in bacteria - - - 0.000000000000000000000000008162 114.0
HSJS3_k127_6172815_0 COG0457 FOG TPR repeat - - - 0.0 1182.0
HSJS3_k127_6172815_1 in Corynebacterium glutamicum this protein can use glutamate, 2-aminobutyrate, and aspartate as amino donors and pyruvate as the acceptor K14260 - 2.6.1.2,2.6.1.66 8.553e-233 724.0
HSJS3_k127_6172815_10 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 332.0
HSJS3_k127_6172815_11 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 337.0
HSJS3_k127_6172815_12 COG0811 Biopolymer transport proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 328.0
HSJS3_k127_6172815_13 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 282.0
HSJS3_k127_6172815_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004171 241.0
HSJS3_k127_6172815_15 COG0848 Biopolymer transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000003444 216.0
HSJS3_k127_6172815_16 COG3001 Fructosamine-3-kinase - - - 0.000000000000000000000000000000000000000000000000000000000001412 220.0
HSJS3_k127_6172815_17 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000000000000000000000000000000000005903 192.0
HSJS3_k127_6172815_18 protein conserved in bacteria K09906 - - 0.00000000000000000000000000000000000000000000000009057 190.0
HSJS3_k127_6172815_19 - - - - 0.00000000000000000000000000000000000000000000001244 176.0
HSJS3_k127_6172815_2 MMPL family K07003 - - 1.248e-202 657.0
HSJS3_k127_6172815_20 - - - - 0.0000000000000000000000000000005502 124.0
HSJS3_k127_6172815_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 521.0
HSJS3_k127_6172815_4 ATP-NAD kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 497.0
HSJS3_k127_6172815_5 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 479.0
HSJS3_k127_6172815_6 MATE efflux family protein K03327 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 376.0
HSJS3_k127_6172815_7 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 373.0
HSJS3_k127_6172815_8 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 341.0
HSJS3_k127_6172815_9 3-methyladenine DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 332.0
HSJS3_k127_6173012_0 Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA K01638 - 2.3.3.9 0.0 1179.0
HSJS3_k127_6173012_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 7.847e-228 713.0
HSJS3_k127_6173012_10 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000002412 237.0
HSJS3_k127_6173012_11 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003741 205.0
HSJS3_k127_6173012_12 High frequency lysogenization protein HflD homolog K07153 - - 0.000000000000000000000000000000000000000000000000002616 189.0
HSJS3_k127_6173012_13 Belongs to the UPF0149 family K07039 - - 0.00000000000000000000000000000000000000000000004063 176.0
HSJS3_k127_6173012_15 protein acetylation - - - 0.000000000000000000003068 99.0
HSJS3_k127_6173012_16 Protein of unknown function (DUF2914) - - - 0.00000000000000004328 85.0
HSJS3_k127_6173012_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 5.143e-206 646.0
HSJS3_k127_6173012_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 482.0
HSJS3_k127_6173012_4 Transcription factor K18850 - 1.14.11.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 418.0
HSJS3_k127_6173012_5 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 405.0
HSJS3_k127_6173012_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 356.0
HSJS3_k127_6173012_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 346.0
HSJS3_k127_6173012_8 GGDEF domain K21019 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 359.0
HSJS3_k127_6173012_9 Pfam:UPF0118 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007549 308.0
HSJS3_k127_6187058_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 5.018e-242 754.0
HSJS3_k127_6187058_1 Belongs to the amidase family K01426 - 3.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 550.0
HSJS3_k127_6187058_10 Cytochrome c K12263 - - 0.0000000000000000000000000000002363 128.0
HSJS3_k127_6187058_11 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.0000000000001424 80.0
HSJS3_k127_6187058_2 Fatty acid hydroxylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 357.0
HSJS3_k127_6187058_3 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 335.0
HSJS3_k127_6187058_4 COG1881 Phospholipid-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 331.0
HSJS3_k127_6187058_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000003805 226.0
HSJS3_k127_6187058_6 Redoxin K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000004947 205.0
HSJS3_k127_6187058_7 Pilin (bacterial filament) K02650 - - 0.00000000000000000000000000000000000000000000006833 174.0
HSJS3_k127_6187058_8 Pirin K06911 - - 0.00000000000000000000000000000000000000000005063 169.0
HSJS3_k127_6187058_9 COG1278 Cold shock proteins K03704 - - 0.000000000000000000000000000000001526 129.0
HSJS3_k127_63653_0 Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA K00219 - 1.3.1.34 4.209e-271 842.0
HSJS3_k127_63653_1 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 1.623e-205 647.0
HSJS3_k127_63653_10 Glutathione S-transferase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000009745 185.0
HSJS3_k127_63653_11 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000008047 109.0
HSJS3_k127_63653_2 MMPL family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 601.0
HSJS3_k127_63653_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 484.0
HSJS3_k127_63653_4 Fatty acid desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 473.0
HSJS3_k127_63653_5 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 357.0
HSJS3_k127_63653_6 PaaX-like protein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001395 271.0
HSJS3_k127_63653_7 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001458 241.0
HSJS3_k127_63653_8 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000008382 229.0
HSJS3_k127_63653_9 Ricin-type beta-trefoil - - - 0.000000000000000000000000000000000000000000000000000007665 214.0
HSJS3_k127_6406892_0 Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation K00322 - 1.6.1.1 1.68e-222 697.0
HSJS3_k127_6406892_1 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 586.0
HSJS3_k127_6406892_10 Belongs to the DnaA family. HdA subfamily K10763 - - 0.000000000000000000000000000000000000000000000000000000000004149 217.0
HSJS3_k127_6406892_11 MGS-like domain K01734 - 4.2.3.3 0.000000000000000000000000000000000000000000000000000000009084 204.0
HSJS3_k127_6406892_12 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000001711 200.0
HSJS3_k127_6406892_13 protein conserved in bacteria K09938 - - 0.000000000000000000000000000000000000000000000000000009598 204.0
HSJS3_k127_6406892_14 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000002851 189.0
HSJS3_k127_6406892_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 556.0
HSJS3_k127_6406892_3 ( 3 oxidation state) methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 522.0
HSJS3_k127_6406892_5 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 363.0
HSJS3_k127_6406892_6 Fe-S oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 363.0
HSJS3_k127_6406892_7 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006442 287.0
HSJS3_k127_6406892_8 START domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002287 256.0
HSJS3_k127_6406892_9 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
HSJS3_k127_6722152_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 1.29e-213 671.0
HSJS3_k127_6722152_1 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000003052 188.0
HSJS3_k127_6723435_0 Involved in the TonB-independent uptake of proteins K03641 - - 8.869e-207 650.0
HSJS3_k127_6723435_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 579.0
HSJS3_k127_6723435_10 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007793 258.0
HSJS3_k127_6723435_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000000000000000000000008658 246.0
HSJS3_k127_6723435_12 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 248.0
HSJS3_k127_6723435_13 Protein of unknown function (DUF1365) K09701 - - 0.0000000000000000000000000000000000000000000000000000000000000000004513 237.0
HSJS3_k127_6723435_14 Biopolymer transport protein K03560 - - 0.000000000000000000000000000000000000000000000000000000001455 204.0
HSJS3_k127_6723435_15 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000003601 202.0
HSJS3_k127_6723435_16 Thioesterase K01075,K07107 - 3.1.2.23 0.000000000000000000000000000000000000000000000000000754 186.0
HSJS3_k127_6723435_17 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000002056 167.0
HSJS3_k127_6723435_18 Transcriptional K22491 - - 0.0000000000000000000000000001218 126.0
HSJS3_k127_6723435_19 Bacterial SH3 domain - - - 0.00000000000006336 78.0
HSJS3_k127_6723435_2 NAD FAD-binding protein K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 565.0
HSJS3_k127_6723435_21 protein serine/threonine phosphatase activity - - - 0.0008138 45.0
HSJS3_k127_6723435_3 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 562.0
HSJS3_k127_6723435_4 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 533.0
HSJS3_k127_6723435_5 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009993 429.0
HSJS3_k127_6723435_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 338.0
HSJS3_k127_6723435_7 MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005663 325.0
HSJS3_k127_6723435_8 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 319.0
HSJS3_k127_6723435_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001309 284.0
HSJS3_k127_6749524_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.0 1595.0
HSJS3_k127_6749524_1 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 1.016e-232 734.0
HSJS3_k127_6749524_10 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 347.0
HSJS3_k127_6749524_11 overlaps another CDS with the same product name K21019 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 337.0
HSJS3_k127_6749524_12 overlaps another CDS with the same product name K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005831 332.0
HSJS3_k127_6749524_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 307.0
HSJS3_k127_6749524_14 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 295.0
HSJS3_k127_6749524_15 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001065 289.0
HSJS3_k127_6749524_16 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009689 252.0
HSJS3_k127_6749524_17 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001257 251.0
HSJS3_k127_6749524_18 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000002993 203.0
HSJS3_k127_6749524_19 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000003714 174.0
HSJS3_k127_6749524_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 4.011e-228 713.0
HSJS3_k127_6749524_20 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000000000000000000002526 173.0
HSJS3_k127_6749524_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.538e-226 713.0
HSJS3_k127_6749524_4 Histidine kinase K07639 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 612.0
HSJS3_k127_6749524_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 - 2.1.3.3,2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 502.0
HSJS3_k127_6749524_6 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 513.0
HSJS3_k127_6749524_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008422 495.0
HSJS3_k127_6749524_8 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006186 423.0
HSJS3_k127_6749524_9 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006405 409.0
HSJS3_k127_67551_0 Sulfite reductase K00381 - 1.8.1.2 6.716e-300 926.0
HSJS3_k127_67551_1 alcohol dehydrogenase K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007838 453.0
HSJS3_k127_67551_2 peptidase K04774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 437.0
HSJS3_k127_67551_3 COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding K03426 - 3.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 296.0
HSJS3_k127_67551_4 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004046 286.0
HSJS3_k127_67551_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006949 277.0
HSJS3_k127_67551_6 Mg2 and Co2 transporters K16074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001688 281.0
HSJS3_k127_67551_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002254 251.0
HSJS3_k127_67551_8 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000001802 123.0
HSJS3_k127_67551_9 Histidine kinase - - - 0.000000000000000002259 86.0
HSJS3_k127_6760595_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 3.294e-221 692.0
HSJS3_k127_6760595_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 1.761e-215 678.0
HSJS3_k127_6760595_10 Membrane - - - 0.000000005477 67.0
HSJS3_k127_6760595_11 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00005441 46.0
HSJS3_k127_6760595_2 due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 486.0
HSJS3_k127_6760595_3 DNA polymerase III K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 368.0
HSJS3_k127_6760595_4 COG3315 O-Methyltransferase involved in polyketide biosynthesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 355.0
HSJS3_k127_6760595_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000002048 255.0
HSJS3_k127_6760595_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000001007 182.0
HSJS3_k127_6760595_7 DJ-1/PfpI family K03152 - 3.5.1.124 0.0000000000000000000000000000000000000000000003782 173.0
HSJS3_k127_6760595_8 serine threonine protein kinase - - - 0.00000000000000000000008375 110.0
HSJS3_k127_6760595_9 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.0000000000000000002702 96.0
HSJS3_k127_6762490_0 Phosphoserine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 303.0
HSJS3_k127_6762490_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001842 265.0
HSJS3_k127_6762490_2 Iron-regulated protein - - - 0.0000000000000000000009809 108.0
HSJS3_k127_6776930_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 467.0
HSJS3_k127_6776930_1 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 359.0
HSJS3_k127_6776930_2 Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA K06169 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 305.0
HSJS3_k127_6776930_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000004728 261.0
HSJS3_k127_6776930_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000006978 218.0
HSJS3_k127_6776930_5 Parallel beta-helix repeats - - - 0.00000000000000000000004391 116.0
HSJS3_k127_6776930_6 2OG-Fe(II) oxygenase superfamily - - - 0.000000000000000000001657 103.0
HSJS3_k127_6794418_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 551.0
HSJS3_k127_6794418_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009685 527.0
HSJS3_k127_6794418_2 COG1538 Outer membrane protein K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005676 402.0
HSJS3_k127_6801540_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.44e-243 758.0
HSJS3_k127_6801540_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K19696 - 2.4.2.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 346.0
HSJS3_k127_6801540_2 Catalyzes the salvage synthesis of inosine-5'-monophosphate (IMP) and guanosine-5'-monophosphate (GMP) from the purine bases hypoxanthine and guanine, respectively K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000003099 216.0
HSJS3_k127_6801540_3 Peptidoglycan-binding protein, CsiV - - - 0.000000000000000000000000000000001201 141.0
HSJS3_k127_6823666_0 Belongs to the GMC oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 381.0
HSJS3_k127_6823666_1 endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 303.0
HSJS3_k127_6823666_2 D-alanine [D-alanyl carrier protein] ligase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 309.0
HSJS3_k127_6823666_3 COG2199 FOG GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001067 280.0
HSJS3_k127_6823666_4 Uncharacterised protein family (UPF0014) K02069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003342 263.0
HSJS3_k127_6823666_5 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000002631 220.0
HSJS3_k127_6823666_6 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000003012 156.0
HSJS3_k127_6823666_7 Cytochrome c - - - 0.0000299 48.0
HSJS3_k127_6823666_8 Protein of unknown function (DUF3080) - - - 0.00003317 47.0
HSJS3_k127_6828894_0 COG1674 DNA segregation ATPase FtsK SpoIIIE and related proteins K03466 GO:0000920,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006355,GO:0006950,GO:0006970,GO:0007059,GO:0008094,GO:0008150,GO:0009628,GO:0009651,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0015616,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033676,GO:0042221,GO:0042623,GO:0042802,GO:0043085,GO:0043565,GO:0044093,GO:0044425,GO:0044459,GO:0044464,GO:0045893,GO:0045935,GO:0046677,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051301,GO:0051716,GO:0060255,GO:0065007,GO:0065009,GO:0070887,GO:0071236,GO:0071944,GO:0080090,GO:0097159,GO:0140097,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 2.905e-290 910.0
HSJS3_k127_6828894_1 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 1.285e-210 663.0
HSJS3_k127_6828894_2 Belongs to the ClpA ClpB family K03694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 567.0
HSJS3_k127_6828894_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 538.0
HSJS3_k127_6828894_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 355.0
HSJS3_k127_6828894_5 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000008516 267.0
HSJS3_k127_6828894_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000573 213.0
HSJS3_k127_6828894_7 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000009762 140.0
HSJS3_k127_6828894_8 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000006798 132.0
HSJS3_k127_6836555_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1172.0
HSJS3_k127_6836555_1 Long-chain fatty acid transport protein - - - 9.515e-285 882.0
HSJS3_k127_6836555_10 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K07400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 361.0
HSJS3_k127_6836555_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 347.0
HSJS3_k127_6836555_12 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 361.0
HSJS3_k127_6836555_13 GntR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 333.0
HSJS3_k127_6836555_14 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 326.0
HSJS3_k127_6836555_15 Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA K11391 - 2.1.1.174 0.000000000000000000000000000000000000000000000000000000000000000000000000001487 269.0
HSJS3_k127_6836555_16 COG2230 Cyclopropane fatty acid synthase and related methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001036 256.0
HSJS3_k127_6836555_17 Pseudouridine synthase K06177 - 5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000001709 259.0
HSJS3_k127_6836555_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002488 230.0
HSJS3_k127_6836555_19 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000134 202.0
HSJS3_k127_6836555_2 ABC1 family protein, ubiquinone biosynthesis protein K03688 - - 2.189e-252 788.0
HSJS3_k127_6836555_20 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000008727 202.0
HSJS3_k127_6836555_21 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001226 190.0
HSJS3_k127_6836555_22 Maltose operon periplasmic protein precursor (MalM) - - - 0.0000000000000000000000000000000000000000000756 170.0
HSJS3_k127_6836555_23 lysine methyltransferase K07117 - - 0.0000000000000000000000000000000000000000001265 162.0
HSJS3_k127_6836555_25 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000003525 108.0
HSJS3_k127_6836555_27 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0008452,GO:0008664,GO:0016787,GO:0016788,GO:0016874,GO:0016886,GO:0042578,GO:0140098 3.1.4.58 0.000000000000001121 84.0
HSJS3_k127_6836555_28 Sulfite reductase K00381 - 1.8.1.2 0.000000048 55.0
HSJS3_k127_6836555_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.627e-252 781.0
HSJS3_k127_6836555_4 unusual protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006141 507.0
HSJS3_k127_6836555_5 Sh3 type 3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 457.0
HSJS3_k127_6836555_6 double-glycine peptidase K06992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 413.0
HSJS3_k127_6836555_7 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K03417 - 4.1.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 398.0
HSJS3_k127_6836555_8 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004313 410.0
HSJS3_k127_6836555_9 COG0147 Anthranilate para-aminobenzoate synthases component I K01665 - 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007614 384.0
HSJS3_k127_6837703_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 1.151e-215 677.0
HSJS3_k127_6837703_1 Protein of unknown function (DUF1275) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006965 261.0
HSJS3_k127_6841603_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 0.0 1162.0
HSJS3_k127_6841603_1 TrkA-C domain - - - 3.569e-236 744.0
HSJS3_k127_6841603_2 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003268 243.0
HSJS3_k127_6841603_3 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000001715 53.0
HSJS3_k127_6866416_0 found to be peripherally associated with the inner membrane in Escherichia coli K03499 - - 5.78e-253 784.0
HSJS3_k127_6866416_1 Trk system potassium uptake protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 509.0
HSJS3_k127_6866416_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 461.0
HSJS3_k127_6866416_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 381.0
HSJS3_k127_6866416_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 283.0
HSJS3_k127_6899325_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000002563 235.0
HSJS3_k127_6899325_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000003085 201.0
HSJS3_k127_6905927_0 DNA polymerase III subunit delta K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 335.0
HSJS3_k127_6905927_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000002037 265.0
HSJS3_k127_6905927_2 Pilus assembly protein PilZ K02676 - - 0.000000000000000000000000000000000000000000000000000000000003361 209.0
HSJS3_k127_6905927_3 TatD family K03424 - - 0.00000000000000000000000000001169 126.0
HSJS3_k127_6918117_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.957e-220 685.0
HSJS3_k127_6918117_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 469.0
HSJS3_k127_6918117_2 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 422.0
HSJS3_k127_6922077_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 366.0
HSJS3_k127_6922077_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 325.0
HSJS3_k127_6922077_2 Specifically methylates the guanosine in position 1516 of 16S rRNA K15984 - 2.1.1.242 0.000000000000000000000000000000000000000000000000053 190.0
HSJS3_k127_6964729_0 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006729 591.0
HSJS3_k127_6964729_1 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 410.0
HSJS3_k127_6964729_2 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 314.0
HSJS3_k127_6964729_3 An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 - 0.0000000000000000000000000000000000000000000002028 169.0
HSJS3_k127_6985554_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1447.0
HSJS3_k127_6985554_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 486.0
HSJS3_k127_6985554_10 - - - - 0.00000000000000000000001366 102.0
HSJS3_k127_6985554_2 Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 406.0
HSJS3_k127_6985554_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006937 405.0
HSJS3_k127_6985554_4 Transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 359.0
HSJS3_k127_6985554_5 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 337.0
HSJS3_k127_6985554_6 High affinity, high specificity proton-dependent sulfate transporter, which mediates sulfate uptake. Provides the sulfur source for the cysteine synthesis pathway K06203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002074 293.0
HSJS3_k127_6985554_7 NlpB/DapX lipoprotein - - - 0.00000000000000000000000000000000000000000000000000001872 198.0
HSJS3_k127_6985554_9 glycine cleavage system K03567 - - 0.00000000000000000000000000215 115.0
HSJS3_k127_6991563_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1354.0
HSJS3_k127_6991563_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00210,K00800 - 1.3.1.12,2.5.1.19 0.0 1106.0
HSJS3_k127_6991563_2 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.983e-314 966.0
HSJS3_k127_6991563_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007562 580.0
HSJS3_k127_6991563_4 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 561.0
HSJS3_k127_6991563_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009681 516.0
HSJS3_k127_6991563_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 345.0
HSJS3_k127_6991563_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.0000000000000000000000000000000000000000000000002117 179.0
HSJS3_k127_6991563_8 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000001276 64.0
HSJS3_k127_6991563_9 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000001082 59.0
HSJS3_k127_7000265_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.551e-317 986.0
HSJS3_k127_7000265_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 1.8e-271 841.0
HSJS3_k127_7000265_10 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 352.0
HSJS3_k127_7000265_11 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008529 327.0
HSJS3_k127_7000265_12 Uracil-DNA glycosylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 289.0
HSJS3_k127_7000265_13 protein conserved in bacteria K05952 - - 0.0000000000000000002804 93.0
HSJS3_k127_7000265_2 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 6.453e-249 770.0
HSJS3_k127_7000265_3 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00347 - 1.6.5.8 2.814e-233 728.0
HSJS3_k127_7000265_4 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 - 1.6.5.8 1.622e-214 674.0
HSJS3_k127_7000265_5 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 542.0
HSJS3_k127_7000265_6 Acyl-CoA thioesterase K10805 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 419.0
HSJS3_k127_7000265_7 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 394.0
HSJS3_k127_7000265_8 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 376.0
HSJS3_k127_7000265_9 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 360.0
HSJS3_k127_7022719_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.0 1986.0
HSJS3_k127_7022719_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 5.015e-308 948.0
HSJS3_k127_7022719_10 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 GO:0003674,GO:0003824,GO:0004644,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008776,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016741,GO:0016742,GO:0016772,GO:0016774,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.2 9.732e-197 618.0
HSJS3_k127_7022719_11 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 2.504e-196 617.0
HSJS3_k127_7022719_12 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 GO:0000027,GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022607,GO:0022613,GO:0022618,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032794,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:0097159,GO:0097216,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 614.0
HSJS3_k127_7022719_13 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 552.0
HSJS3_k127_7022719_14 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 532.0
HSJS3_k127_7022719_15 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 509.0
HSJS3_k127_7022719_16 COG0436 Aspartate tyrosine aromatic aminotransferase K12252,K14261 - 2.6.1.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 484.0
HSJS3_k127_7022719_17 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 484.0
HSJS3_k127_7022719_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 444.0
HSJS3_k127_7022719_19 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 427.0
HSJS3_k127_7022719_2 serine threonine protein kinase K12132 - 2.7.11.1 6.775e-287 905.0
HSJS3_k127_7022719_20 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 340.0
HSJS3_k127_7022719_21 ADP-ribose pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 323.0
HSJS3_k127_7022719_22 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008652 317.0
HSJS3_k127_7022719_23 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 316.0
HSJS3_k127_7022719_24 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008376 297.0
HSJS3_k127_7022719_25 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 297.0
HSJS3_k127_7022719_26 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
HSJS3_k127_7022719_27 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
HSJS3_k127_7022719_28 COG3063 Tfp pilus assembly protein PilF K02656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003745 259.0
HSJS3_k127_7022719_29 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003129 252.0
HSJS3_k127_7022719_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.992e-270 836.0
HSJS3_k127_7022719_30 protein possibly involved in aromatic compounds catabolism - - - 0.00000000000000000000000000000000000000000000000000000000000000000002742 239.0
HSJS3_k127_7022719_31 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000000000006402 231.0
HSJS3_k127_7022719_32 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000000000000000000005028 233.0
HSJS3_k127_7022719_33 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000003474 218.0
HSJS3_k127_7022719_34 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000003296 203.0
HSJS3_k127_7022719_35 DoxX K15977 - - 0.00000000000000000000000000000000000000000000000004424 184.0
HSJS3_k127_7022719_36 AMMECR1 - - - 0.000000000000000000000000000000000000000000000008217 177.0
HSJS3_k127_7022719_37 protein conserved in bacteria K15539 - - 0.00000000000000000000000000000000000000000000003852 180.0
HSJS3_k127_7022719_38 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000026 162.0
HSJS3_k127_7022719_39 - - - - 0.000000000000000000000000000000000000000003318 160.0
HSJS3_k127_7022719_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 7.406e-245 762.0
HSJS3_k127_7022719_40 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000003662 158.0
HSJS3_k127_7022719_41 transport system, periplasmic component - - - 0.000000000000000000000000000000000000002775 157.0
HSJS3_k127_7022719_42 Ribosomal protein S16 K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000003664 132.0
HSJS3_k127_7022719_43 Cysteine desulfurase activator complex subunit SufB K09014 - - 0.0000000000000000001204 90.0
HSJS3_k127_7022719_44 Fe-S protein K06938 - - 0.0000000000000000003705 88.0
HSJS3_k127_7022719_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 2.18e-218 680.0
HSJS3_k127_7022719_6 histidyl-tRNA synthetase K01892 - 6.1.1.21 4.963e-213 669.0
HSJS3_k127_7022719_7 COG1629 Outer membrane receptor proteins, mostly Fe transport K02014 - - 2.314e-209 673.0
HSJS3_k127_7022719_8 Mg2 and Co2 transporter CorB - - - 4.224e-209 656.0
HSJS3_k127_7022719_9 Uncharacterised signal transduction histidine kinase domain (DUF2222) K20974 - 2.7.13.3 8.862e-205 657.0
HSJS3_k127_7031127_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1354.0
HSJS3_k127_7031127_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 7.508e-234 732.0
HSJS3_k127_7031127_10 Catalyzes the phosphorylation of heptose(I) of the outer membrane lipopolysaccharide core K02848 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 396.0
HSJS3_k127_7031127_11 Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)- (lauroyl)-lipid IV(A) K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 376.0
HSJS3_k127_7031127_12 Aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005686 362.0
HSJS3_k127_7031127_13 Glycosyltransferase like family 2 K00786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 302.0
HSJS3_k127_7031127_14 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005366 278.0
HSJS3_k127_7031127_15 Membrane protein implicated in regulation of membrane protease activity K07340 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000006956 118.0
HSJS3_k127_7031127_16 - - - - 0.000000000000002563 89.0
HSJS3_k127_7031127_2 type II secretion system protein K02454 - - 3.764e-226 715.0
HSJS3_k127_7031127_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 533.0
HSJS3_k127_7031127_4 heptosyltransferase K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 497.0
HSJS3_k127_7031127_5 COG0578 Glycerol-3-phosphate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 448.0
HSJS3_k127_7031127_6 COG0859 ADP-heptose LPS heptosyltransferase K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007864 435.0
HSJS3_k127_7031127_7 COG0330 Membrane protease subunits stomatin prohibitin homologs - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 417.0
HSJS3_k127_7031127_8 epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 413.0
HSJS3_k127_7031127_9 Glycosyl transferases group 1 K02844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 403.0
HSJS3_k127_7039847_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009314,GO:0009338,GO:0009628,GO:0009987,GO:0015616,GO:0016043,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032392,GO:0032508,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044355,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0099046,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 0.0 1090.0
HSJS3_k127_7039847_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0 1059.0
HSJS3_k127_7039847_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 267.0
HSJS3_k127_7039847_11 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001642 265.0
HSJS3_k127_7039847_12 chemotaxis K03406 - - 0.0000000000000000000000000000000000000000000000000000008366 211.0
HSJS3_k127_7039847_13 PFAM helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000000000000000000000000000000004827 183.0
HSJS3_k127_7039847_14 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000006704 175.0
HSJS3_k127_7039847_15 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000001852 142.0
HSJS3_k127_7039847_16 Calcineurin-like phosphoesterase K14379 - 3.1.3.2 0.00000000000000000000000000000000002216 142.0
HSJS3_k127_7039847_17 consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000108 140.0
HSJS3_k127_7039847_18 Two component signalling adaptor domain - - - 0.000000000000000000008018 107.0
HSJS3_k127_7039847_19 Histidine kinase - - - 0.00000000000000006102 83.0
HSJS3_k127_7039847_2 flavoprotein involved in K transport - - - 1.793e-203 644.0
HSJS3_k127_7039847_20 PFAM FecR protein - - - 0.00000004244 66.0
HSJS3_k127_7039847_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 GO:0000166,GO:0000724,GO:0000725,GO:0003674,GO:0003824,GO:0004386,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0008854,GO:0009338,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016796,GO:0016817,GO:0016818,GO:0016887,GO:0016895,GO:0017076,GO:0017111,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043142,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006563 558.0
HSJS3_k127_7039847_4 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 518.0
HSJS3_k127_7039847_5 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 416.0
HSJS3_k127_7039847_6 Two component signalling adaptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 410.0
HSJS3_k127_7039847_7 consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 360.0
HSJS3_k127_7039847_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 375.0
HSJS3_k127_7039847_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001644 284.0
HSJS3_k127_7040548_0 Putative diguanylate phosphodiesterase K21025 - - 5.496e-272 852.0
HSJS3_k127_7040548_1 phosphoserine phosphatase K01079 - 3.1.3.3 1.486e-218 683.0
HSJS3_k127_7040548_10 TM2 domain - - - 0.000001532 60.0
HSJS3_k127_7040548_11 - - - - 0.000002185 60.0
HSJS3_k127_7040548_2 - - - - 3.849e-194 623.0
HSJS3_k127_7040548_3 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 610.0
HSJS3_k127_7040548_4 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005448 378.0
HSJS3_k127_7040548_5 TIGRFAM lysine 2,3-aminomutase YodO family protein K01843,K19810 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 375.0
HSJS3_k127_7040548_6 Involved in peptide bond synthesis. Alleviates ribosome stalling that occurs when 3 or more consecutive Pro residues or the sequence PPG is present in a protein, possibly by augmenting the peptidyl transferase activity of the ribosome. Modification of Lys-34 is required for alleviation K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 347.0
HSJS3_k127_7040548_7 Elongation factor P--(R)-beta-lysine ligase K04568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 342.0
HSJS3_k127_7040548_8 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000002344 226.0
HSJS3_k127_7040548_9 TM2 domain - - - 0.0000000008532 71.0
HSJS3_k127_7048921_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1418.0
HSJS3_k127_7048921_1 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1223.0
HSJS3_k127_7048921_10 carboxylic ester hydrolase activity K01054 - 3.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 362.0
HSJS3_k127_7048921_11 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 331.0
HSJS3_k127_7048921_12 COG1234 Metal-dependent hydrolases of the beta-lactamase superfamily III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 331.0
HSJS3_k127_7048921_13 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 319.0
HSJS3_k127_7048921_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 323.0
HSJS3_k127_7048921_15 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 320.0
HSJS3_k127_7048921_16 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000852 290.0
HSJS3_k127_7048921_17 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001443 271.0
HSJS3_k127_7048921_18 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003671 267.0
HSJS3_k127_7048921_19 Protein of unknown function (DUF1348) K09958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001973 253.0
HSJS3_k127_7048921_2 Belongs to the BCCT transporter (TC 2.A.15) family K02168 - - 3.32e-286 894.0
HSJS3_k127_7048921_20 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000002188 250.0
HSJS3_k127_7048921_21 Protein of unknown function (DUF2505) - - - 0.00000000000000000000000000000000000000000000000000002464 193.0
HSJS3_k127_7048921_22 - - - - 0.000000000000000000000000000000000000000000000003157 177.0
HSJS3_k127_7048921_23 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000001221 176.0
HSJS3_k127_7048921_24 OmpA-like transmembrane domain - - - 0.000000000000000000000000000000000000004811 162.0
HSJS3_k127_7048921_25 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000004143 130.0
HSJS3_k127_7048921_26 Protein of unknown function (DUF2834) - - - 0.00000000000000000000000000006295 121.0
HSJS3_k127_7048921_27 - - - - 0.0000000000000000000000000002191 123.0
HSJS3_k127_7048921_28 - - - - 0.000000000000000000000007433 106.0
HSJS3_k127_7048921_3 Amidohydrolase family - - - 1.214e-229 724.0
HSJS3_k127_7048921_4 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 561.0
HSJS3_k127_7048921_5 Male sterility protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 509.0
HSJS3_k127_7048921_6 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 430.0
HSJS3_k127_7048921_7 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 426.0
HSJS3_k127_7048921_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 421.0
HSJS3_k127_7048921_9 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002875 365.0
HSJS3_k127_7072803_0 P-type ATPase K01533 - 3.6.3.4 3.038e-209 676.0
HSJS3_k127_7072803_1 COG0348 Polyferredoxin - - - 3.195e-201 637.0
HSJS3_k127_7072803_2 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 2.235e-197 624.0
HSJS3_k127_7072803_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000000000000000000000000000000000000000000000002494 202.0
HSJS3_k127_7072803_4 FixH K09926 - - 0.000000000000000000000000000002293 127.0
HSJS3_k127_7072803_5 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000001275 92.0
HSJS3_k127_7072803_6 Cytochrome oxidase maturation protein - - - 0.000000009597 63.0
HSJS3_k127_7072803_7 transcriptional regulator K01420 - - 0.0000001226 54.0
HSJS3_k127_7088716_0 Alpha-2-Macroglobulin K06894 - - 0.0 1621.0
HSJS3_k127_7088716_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 5.668e-279 878.0
HSJS3_k127_7088716_10 Lipocalin-like domain K03098 - - 0.000000000000000004005 86.0
HSJS3_k127_7088716_2 Alkane 1-monooxygenase K00496 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 3.219e-194 612.0
HSJS3_k127_7088716_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002585 478.0
HSJS3_k127_7088716_4 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 338.0
HSJS3_k127_7088716_5 Fatty acid hydroxylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004693 283.0
HSJS3_k127_7088716_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000001905 201.0
HSJS3_k127_7088716_7 Protein of unknown function (DUF3080) - - - 0.00000000000000000000000000000000000000000000000005772 190.0
HSJS3_k127_7088716_8 PFAM DoxX K15977 - - 0.000000000000000000000000000000000000000003566 158.0
HSJS3_k127_7088716_9 Outer Membrane Lipoprotein K03098 - - 0.00000000000000000000000000001415 119.0
HSJS3_k127_7131674_0 Ompa motb domain protein - - - 0.0 2361.0
HSJS3_k127_7131674_1 Domain of unknown function DUF11 - - - 0.0 1191.0
HSJS3_k127_7131674_10 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 349.0
HSJS3_k127_7131674_11 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 326.0
HSJS3_k127_7131674_12 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 304.0
HSJS3_k127_7131674_13 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006464,GO:0006479,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0010468,GO:0016043,GO:0016740,GO:0016741,GO:0018364,GO:0019222,GO:0019538,GO:0022411,GO:0032259,GO:0032984,GO:0034641,GO:0034645,GO:0036009,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043414,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 297.0
HSJS3_k127_7131674_14 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 293.0
HSJS3_k127_7131674_15 Domain of unknown function (DUF4398) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003617 258.0
HSJS3_k127_7131674_16 membrane protein domain - - - 0.00000000000000000000000000000000000000000000000000000000000000865 219.0
HSJS3_k127_7131674_17 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000000000000002324 193.0
HSJS3_k127_7131674_18 OmpA-like transmembrane domain - - - 0.00000000000000000000000000000000000144 144.0
HSJS3_k127_7131674_19 PAS domain - - - 0.000000000000000000000000000000008187 135.0
HSJS3_k127_7131674_2 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 9.095e-319 996.0
HSJS3_k127_7131674_20 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000004714 124.0
HSJS3_k127_7131674_21 Domain of unknown function (DUF4398) - - - 0.000000000000000000004336 97.0
HSJS3_k127_7131674_22 - - - - 0.00000000000001229 75.0
HSJS3_k127_7131674_23 Protein of unknown function (DUF3185) - - - 0.0000000003247 64.0
HSJS3_k127_7131674_24 CsbD-like - - - 0.000000000622 63.0
HSJS3_k127_7131674_25 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0000287,GO:0003674,GO:0003824,GO:0004749,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006015,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042301,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046391,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.00001155 48.0
HSJS3_k127_7131674_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 610.0
HSJS3_k127_7131674_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 571.0
HSJS3_k127_7131674_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 569.0
HSJS3_k127_7131674_6 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007231 556.0
HSJS3_k127_7131674_7 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 529.0
HSJS3_k127_7131674_8 Diguanylate cyclase with PAS PAC sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 408.0
HSJS3_k127_7131674_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 358.0
HSJS3_k127_7142393_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 576.0
HSJS3_k127_7142393_1 SURF1-like protein K14998 - - 0.00000000000000000000000000000000000000000000000000000000001568 214.0
HSJS3_k127_7142393_2 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000001618 201.0
HSJS3_k127_7142393_3 signal sequence binding - - - 0.00000000000000000000000000000000000000000000000000001526 194.0
HSJS3_k127_7142393_4 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000195 185.0
HSJS3_k127_7142393_5 protein required for cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000009367 154.0
HSJS3_k127_7142393_6 Protein of unknown function (DUF2909) - - - 0.0000000000000000000002297 99.0
HSJS3_k127_7149574_0 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 363.0
HSJS3_k127_7149574_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000001198 230.0
HSJS3_k127_7149574_2 Acetyltransferase (GNAT) domain - - - 0.000000000000003837 87.0
HSJS3_k127_7149574_3 Sugar ABC transporter substrate-binding protein K01991 - - 0.00000000004024 64.0
HSJS3_k127_7149574_4 O-Antigen ligase - - - 0.0000004655 57.0
HSJS3_k127_7171639_0 May be involved in recombinational repair of damaged DNA K03631 - - 2.279e-225 711.0
HSJS3_k127_7171639_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 517.0
HSJS3_k127_7171639_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000001835 224.0
HSJS3_k127_7171639_3 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000001659 201.0
HSJS3_k127_7171639_4 membrane protein domain - - - 0.00000000000000000000000000000000000000000000000000000002691 201.0
HSJS3_k127_7171639_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000000000000000001149 180.0
HSJS3_k127_7171639_6 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000000000000000000000001939 131.0
HSJS3_k127_7171639_7 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.0000000000000000000000009095 108.0
HSJS3_k127_7176448_0 Ammonium transporter K03320 - - 1.022e-226 707.0
HSJS3_k127_7176448_1 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 538.0
HSJS3_k127_7176448_10 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000001287 59.0
HSJS3_k127_7176448_2 Thioredoxin domain-containing protein K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 369.0
HSJS3_k127_7176448_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 349.0
HSJS3_k127_7176448_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006626 260.0
HSJS3_k127_7176448_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002076 256.0
HSJS3_k127_7176448_6 sterol carrier protein - - - 0.00000000000000000000000000000000000000000000000000000000002507 208.0
HSJS3_k127_7176448_7 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000000000000000000000002376 205.0
HSJS3_k127_7176448_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000003426 182.0
HSJS3_k127_7176448_9 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.00000000000000000000000000000000000001389 157.0
HSJS3_k127_7182065_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.201e-260 804.0
HSJS3_k127_7182065_1 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 2.183e-230 719.0
HSJS3_k127_7182065_2 Belongs to the GppA Ppx family K01524 - 3.6.1.11,3.6.1.40 4.258e-215 677.0
HSJS3_k127_7182065_3 amino acid aldolase or racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 569.0
HSJS3_k127_7182065_4 COG0277 FAD FMN-containing dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004472 562.0
HSJS3_k127_7182065_5 Pyridoxal-phosphate dependent enzyme K01505 - 3.5.99.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005508 316.0
HSJS3_k127_7182065_6 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000904 203.0
HSJS3_k127_7182065_7 Protein of unknown function (DUF1244) K09948 - - 0.000000000000000000000000000000000000000006266 156.0
HSJS3_k127_7182065_8 - - - - 0.000004655 57.0
HSJS3_k127_7189317_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1119.0
HSJS3_k127_7189317_1 pyrophosphohydrolase K04765 - 3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 346.0
HSJS3_k127_7189317_2 COG3203 Outer membrane protein (porin) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005056 253.0
HSJS3_k127_7195255_0 Sulfate permease family K03321 - - 3.442e-238 749.0
HSJS3_k127_7195255_1 Glutathione S-Transferase K00799,K11209 - 2.5.1.18 0.00000000000000000000000000000000000424 138.0
HSJS3_k127_7195255_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000003619 119.0
HSJS3_k127_7233402_0 Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate K00265 - 1.4.1.13,1.4.1.14 0.0 1469.0
HSJS3_k127_7233402_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 2.816e-321 1005.0
HSJS3_k127_7233402_10 domain, Protein K03112 - - 0.00000000000000000000000000000000004868 148.0
HSJS3_k127_7233402_11 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000525 124.0
HSJS3_k127_7233402_2 Type II and III secretion system protein K02507,K02666 - - 8.042e-262 825.0
HSJS3_k127_7233402_3 Malate dehydrogenase K00027,K00029 - 1.1.1.38,1.1.1.40 6.923e-240 745.0
HSJS3_k127_7233402_4 Pilus assembly protein K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 576.0
HSJS3_k127_7233402_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006246 467.0
HSJS3_k127_7233402_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000001397 261.0
HSJS3_k127_7233402_7 Type 4 fimbrial biogenesis protein PilP K02665 - - 0.000000000000000000000000000000000000000000000000000000000000000001319 233.0
HSJS3_k127_7233402_8 Pilus assembly protein PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000001535 233.0
HSJS3_k127_7233402_9 pilus assembly protein PilN K02663 - - 0.0000000000000000000000000000000000000000000000000000000004165 208.0
HSJS3_k127_7248519_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1408.0
HSJS3_k127_7248519_1 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000000000001559 135.0
HSJS3_k127_7248519_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000007552 59.0
HSJS3_k127_7269395_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 6.864e-271 838.0
HSJS3_k127_7269395_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002872 566.0
HSJS3_k127_7269395_2 COG2993 Cbb3-type cytochrome oxidase, cytochrome c subunit K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 355.0
HSJS3_k127_7269395_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 340.0
HSJS3_k127_7269395_4 membrane - - - 0.00000000000000000000000000000000000000000000000000000001099 200.0
HSJS3_k127_7269395_5 protein conserved in bacteria - - - 0.000000000000000000000000002352 117.0
HSJS3_k127_7269395_6 Cbb3-type cytochrome oxidase K00407 - - 0.00002133 50.0
HSJS3_k127_7308221_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 1.336e-263 822.0
HSJS3_k127_7308221_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 537.0
HSJS3_k127_7308221_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 430.0
HSJS3_k127_7308221_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 415.0
HSJS3_k127_7308221_4 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000004136 211.0
HSJS3_k127_7308221_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000000000001056 109.0
HSJS3_k127_7308221_6 - - - - 0.0000000000000001301 83.0
HSJS3_k127_7308221_7 - - - - 0.00000007449 60.0
HSJS3_k127_7329656_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 563.0
HSJS3_k127_7329656_1 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 405.0
HSJS3_k127_7329656_2 IgGFc binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 355.0
HSJS3_k127_7329656_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 286.0
HSJS3_k127_7329656_4 CarboxypepD_reg-like domain - - - 0.0000000000000000000000000000000000000000000000000000008973 219.0
HSJS3_k127_7329656_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000007616 150.0
HSJS3_k127_7329656_6 protein-S-isoprenylcysteine methyltransferase - - - 0.00000000000000000000000000008279 122.0
HSJS3_k127_7379653_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 6.533e-259 811.0
HSJS3_k127_7379653_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 552.0
HSJS3_k127_7379653_10 COG0625 Glutathione S-transferase - - - 0.000000008745 57.0
HSJS3_k127_7379653_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 542.0
HSJS3_k127_7379653_3 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 542.0
HSJS3_k127_7379653_4 Acts on the D-isomers of alanine, leucine, aspartate, glutamate, aminobutyrate, norvaline and asparagine. The enzyme transfers an amino group from a substrate D-amino acid to the pyridoxal phosphate cofactor to form pyridoxamine and an alpha- keto acid in the first half-reaction K00824 - 2.6.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 428.0
HSJS3_k127_7379653_5 Lytic murein transglycosylase B K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 392.0
HSJS3_k127_7379653_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003179 278.0
HSJS3_k127_7379653_7 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004266 259.0
HSJS3_k127_7379653_8 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000000000000000000000000000000000000000000007535 216.0
HSJS3_k127_7379653_9 Belongs to the UPF0250 family K09158 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000008017 115.0
HSJS3_k127_7509014_0 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001217 282.0
HSJS3_k127_7509014_1 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001657 282.0
HSJS3_k127_7509014_2 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009345 258.0
HSJS3_k127_7509014_3 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000003686 205.0
HSJS3_k127_7509014_4 Acyltransferase - - - 0.000000000000000000000000000000000000000002387 156.0
HSJS3_k127_7509014_5 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000001857 158.0
HSJS3_k127_7509014_6 Phage shock protein A (IM30), suppresses sigma54-dependent transcription - - - 0.00000000000000000000000000000000000394 146.0
HSJS3_k127_7509014_7 TfoX N-terminal domain - - - 0.00000000000000000000000000000000005089 137.0
HSJS3_k127_7509014_8 - - - - 0.0000000000000000001559 94.0
HSJS3_k127_7511468_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.174e-233 726.0
HSJS3_k127_7511468_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008283 585.0
HSJS3_k127_7511468_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 526.0
HSJS3_k127_7511468_3 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 379.0
HSJS3_k127_7563731_0 esterase of the alpha-beta hydrolase superfamily K07001 - - 1.825e-249 776.0
HSJS3_k127_7563731_1 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 523.0
HSJS3_k127_7563731_10 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000005775 220.0
HSJS3_k127_7563731_11 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000002099 218.0
HSJS3_k127_7563731_12 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000000002855 182.0
HSJS3_k127_7563731_13 Protein of unknown function (DUF541) K09807 - - 0.0000000000000000000000000000000000000000003569 166.0
HSJS3_k127_7563731_14 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000016 147.0
HSJS3_k127_7563731_2 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 533.0
HSJS3_k127_7563731_3 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 489.0
HSJS3_k127_7563731_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 443.0
HSJS3_k127_7563731_5 COG0451 Nucleoside-diphosphate-sugar epimerases K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 430.0
HSJS3_k127_7563731_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 417.0
HSJS3_k127_7563731_7 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 390.0
HSJS3_k127_7563731_8 COG0642 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 342.0
HSJS3_k127_7563731_9 Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle K00564 - 2.1.1.172 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 298.0
HSJS3_k127_7594798_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1368.0
HSJS3_k127_7594798_1 COG1960 Acyl-CoA dehydrogenases K00249,K06445 - 1.3.8.7 0.0 1189.0
HSJS3_k127_7594798_2 Thrombospondin type 3 repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000904 413.0
HSJS3_k127_7594798_3 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 344.0
HSJS3_k127_7594798_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 334.0
HSJS3_k127_7594798_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000117 261.0
HSJS3_k127_7594798_6 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000004196 247.0
HSJS3_k127_7760816_0 N-methylhydantoinase A acetone carboxylase, beta subunit K01469,K01473 - 3.5.2.14,3.5.2.9 2.115e-238 753.0
HSJS3_k127_7760816_1 COG1398 Fatty-acid desaturase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 589.0
HSJS3_k127_7760816_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 404.0
HSJS3_k127_7760816_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000003875 214.0
HSJS3_k127_7760816_4 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000000000000000000002822 149.0
HSJS3_k127_7760816_5 Belongs to the bacterial ribosomal protein bL33 family K02913 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046677,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000005476 87.0
HSJS3_k127_78211_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1436.0
HSJS3_k127_78211_1 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0 1200.0
HSJS3_k127_78211_10 oxidoreductase FAD NAD(P)-binding K14581 - 1.18.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008952 302.0
HSJS3_k127_78211_11 Alkane 1-monooxygenase K00496,K10616,K15757 - 1.14.15.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001027 293.0
HSJS3_k127_78211_12 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004272 287.0
HSJS3_k127_78211_13 Predicted membrane protein (DUF2157) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003855 286.0
HSJS3_k127_78211_14 COGs COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008363 266.0
HSJS3_k127_78211_15 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000004049 212.0
HSJS3_k127_78211_16 membrane K08974 - - 0.00000000000000000000000000000000000000000000000005997 181.0
HSJS3_k127_78211_17 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000001289 175.0
HSJS3_k127_78211_19 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000007361 173.0
HSJS3_k127_78211_2 exporters of the RND superfamily K07003 - - 0.0 1071.0
HSJS3_k127_78211_20 protein conserved in bacteria - - - 0.0000000000000000000000000000000000001295 145.0
HSJS3_k127_78211_21 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000005429 146.0
HSJS3_k127_78211_22 GDYXXLXY protein - - - 0.00000000000000000000000000000002437 135.0
HSJS3_k127_78211_23 Protein of unknown function (DUF805) - - - 0.0000000000000000000000000001256 126.0
HSJS3_k127_78211_24 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000009793 111.0
HSJS3_k127_78211_25 - - - - 0.000000000000000000005291 94.0
HSJS3_k127_78211_26 Arabinose-binding domain of AraC transcription regulator, N-term - - - 0.000000007745 66.0
HSJS3_k127_78211_3 Glucose / Sorbosone dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 441.0
HSJS3_k127_78211_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 398.0
HSJS3_k127_78211_5 hemolysin activation secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 382.0
HSJS3_k127_78211_6 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 358.0
HSJS3_k127_78211_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 340.0
HSJS3_k127_78211_8 nucleotidyltransferase DNA polymerase involved in DNA repair K14161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 316.0
HSJS3_k127_78211_9 Penicillin-insensitive murein endopeptidase K07261 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006212 299.0
HSJS3_k127_7854855_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 9.177e-244 760.0
HSJS3_k127_7854855_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474,K13015 - 1.1.1.136 6.019e-214 672.0
HSJS3_k127_7854855_10 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001518 257.0
HSJS3_k127_7854855_11 COG2207 AraC-type DNA-binding domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000001873 229.0
HSJS3_k127_7854855_12 COG0517 FOG CBS domain - - - 0.00000000000000000000000000000000000000000000004727 173.0
HSJS3_k127_7854855_13 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000007956 111.0
HSJS3_k127_7854855_2 L-lysine 6-monooxygenase (NADPH-requiring) K07222 - - 3.302e-200 632.0
HSJS3_k127_7854855_3 COG0451 Nucleoside-diphosphate-sugar epimerases K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
HSJS3_k127_7854855_4 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 415.0
HSJS3_k127_7854855_5 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 414.0
HSJS3_k127_7854855_6 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 349.0
HSJS3_k127_7854855_7 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 322.0
HSJS3_k127_7854855_8 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008004 290.0
HSJS3_k127_7854855_9 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 261.0
HSJS3_k127_7974650_0 - - - - 0.0 1029.0
HSJS3_k127_7974650_1 Protein of unknown function (DUF3604) - - - 1.962e-260 818.0
HSJS3_k127_7974650_10 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 447.0
HSJS3_k127_7974650_11 MASE2 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 452.0
HSJS3_k127_7974650_12 HupE / UreJ protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 435.0
HSJS3_k127_7974650_13 Belongs to the MtfA family K09933 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0006508,GO:0006807,GO:0008134,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009889,GO:0010468,GO:0010556,GO:0016787,GO:0019219,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0043170,GO:0043433,GO:0044092,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0050789,GO:0050794,GO:0051090,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0065009,GO:0070011,GO:0071704,GO:0080090,GO:0140096,GO:1901564,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 400.0
HSJS3_k127_7974650_14 haloacid K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 389.0
HSJS3_k127_7974650_15 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 392.0
HSJS3_k127_7974650_16 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008773 345.0
HSJS3_k127_7974650_17 A predicted alpha-helical domain with a conserved ER motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 322.0
HSJS3_k127_7974650_18 pseudouridine methyltransferase K16317 - 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 309.0
HSJS3_k127_7974650_19 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 326.0
HSJS3_k127_7974650_2 Circularly permuted ATP-grasp type 2 - - - 9.902e-252 782.0
HSJS3_k127_7974650_20 Proteasome subunit K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 308.0
HSJS3_k127_7974650_21 HupE / UreJ protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 304.0
HSJS3_k127_7974650_22 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 296.0
HSJS3_k127_7974650_23 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001819 299.0
HSJS3_k127_7974650_24 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000082 277.0
HSJS3_k127_7974650_25 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003922 266.0
HSJS3_k127_7974650_26 Male sterility protein K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000005215 264.0
HSJS3_k127_7974650_27 May be involved in the folding of the extracellular lipase during its passage through the periplasm - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005075 258.0
HSJS3_k127_7974650_28 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001062 238.0
HSJS3_k127_7974650_29 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000351 231.0
HSJS3_k127_7974650_3 Sodium proton antiporter - - - 1.898e-235 736.0
HSJS3_k127_7974650_30 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000008206 214.0
HSJS3_k127_7974650_31 restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000003133 203.0
HSJS3_k127_7974650_32 Conserved repeat domain - - - 0.00000000000000000000000000000000000000000000000000659 191.0
HSJS3_k127_7974650_33 AraC family - - - 0.0000000000000000000000000000000000000256 155.0
HSJS3_k127_7974650_34 membrane K09790 - - 0.0000000000000000000000000000000000001295 145.0
HSJS3_k127_7974650_35 protein conserved in bacteria K09912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000003864 148.0
HSJS3_k127_7974650_36 - - - - 0.0000000000000000000000000000000000966 139.0
HSJS3_k127_7974650_37 - - - - 0.0000000000000000000000000000000002799 136.0
HSJS3_k127_7974650_38 - - - - 0.000000000000000000000000000000001199 133.0
HSJS3_k127_7974650_39 Transcriptional regulator - - - 0.000000000000000000000000000006848 133.0
HSJS3_k127_7974650_4 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00121 - 1.1.1.1,1.1.1.284 4.324e-221 687.0
HSJS3_k127_7974650_40 HDOD domain - - - 0.00000000000000000000000000008349 133.0
HSJS3_k127_7974650_41 - - - - 0.00000000000001209 77.0
HSJS3_k127_7974650_5 Belongs to the amidase family K01426 - 3.5.1.4 4.831e-219 689.0
HSJS3_k127_7974650_6 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 556.0
HSJS3_k127_7974650_7 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 535.0
HSJS3_k127_7974650_8 flavoproteins K07007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 519.0
HSJS3_k127_7974650_9 Alpha beta hydrolase K01046 GO:0003674,GO:0003824,GO:0004806,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0052689,GO:0071704,GO:1901575 3.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 503.0
HSJS3_k127_8042635_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1125.0
HSJS3_k127_8042635_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 453.0
HSJS3_k127_8042635_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 386.0
HSJS3_k127_8042635_3 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 372.0
HSJS3_k127_8042635_4 mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 353.0
HSJS3_k127_8042635_5 COG1428 Deoxynucleoside kinases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007319 318.0
HSJS3_k127_8042635_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 293.0
HSJS3_k127_8042635_7 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000006582 235.0
HSJS3_k127_8042635_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 GO:0000287,GO:0003674,GO:0003824,GO:0003848,GO:0005488,GO:0016740,GO:0016772,GO:0016778,GO:0043167,GO:0043169,GO:0046872 2.7.6.3 0.00000000000000000000000000000000000000004754 159.0
HSJS3_k127_8043842_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1300.0
HSJS3_k127_8043842_1 Acyltransferase - - - 1.223e-310 968.0
HSJS3_k127_8043842_10 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
HSJS3_k127_8043842_11 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000003149 249.0
HSJS3_k127_8043842_12 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000009047 207.0
HSJS3_k127_8043842_13 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000003835 156.0
HSJS3_k127_8043842_14 Phage shock protein A (IM30), suppresses sigma54-dependent transcription - - - 0.000000000000000000000000000000000004958 147.0
HSJS3_k127_8043842_15 TfoX N-terminal domain - - - 0.00000000000000000000000000000000001 138.0
HSJS3_k127_8043842_16 - - - - 0.000000000000000000008952 98.0
HSJS3_k127_8043842_2 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 2.839e-283 886.0
HSJS3_k127_8043842_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.689e-209 657.0
HSJS3_k127_8043842_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 580.0
HSJS3_k127_8043842_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 549.0
HSJS3_k127_8043842_6 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 350.0
HSJS3_k127_8043842_7 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 307.0
HSJS3_k127_8043842_8 DNA-3-methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 281.0
HSJS3_k127_8043842_9 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006504 269.0
HSJS3_k127_8061781_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.347e-256 796.0
HSJS3_k127_8061781_1 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 2.373e-253 787.0
HSJS3_k127_8061781_11 - - - - 0.000003196 50.0
HSJS3_k127_8061781_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 3.991e-214 668.0
HSJS3_k127_8061781_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 547.0
HSJS3_k127_8061781_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 486.0
HSJS3_k127_8061781_5 nucleoside-diphosphate sugar epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 376.0
HSJS3_k127_8061781_6 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 349.0
HSJS3_k127_8061781_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 349.0
HSJS3_k127_8061781_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004436 256.0
HSJS3_k127_8061781_9 phosphohistidine phosphatase K08296 - - 0.0000000000000000000000000000000000002261 145.0
HSJS3_k127_8062565_0 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 8.372e-228 708.0
HSJS3_k127_8062565_1 twitching motility protein K02670 - - 4.992e-222 690.0
HSJS3_k127_8062565_10 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 0.00000419 49.0
HSJS3_k127_8062565_2 twitching motility protein K02669 - - 1.573e-206 646.0
HSJS3_k127_8062565_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 378.0
HSJS3_k127_8062565_4 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 319.0
HSJS3_k127_8062565_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 294.0
HSJS3_k127_8062565_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005843 280.0
HSJS3_k127_8062565_7 Integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000000000000000004466 236.0
HSJS3_k127_8062565_8 DUF167 K09131 - - 0.000000000000000000000002078 106.0
HSJS3_k127_8062565_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000005284 89.0
HSJS3_k127_8063167_0 Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present K03657 - 3.6.4.12 2.633e-202 636.0
HSJS3_k127_8063167_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 9.391e-199 638.0
HSJS3_k127_8063167_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 559.0
HSJS3_k127_8063167_3 ABC-type amino acid transport signal transduction systems periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001332 290.0
HSJS3_k127_8063167_4 hydrolase K10806 - - 0.00000000000000000000000000000000000000000000000000000003901 200.0
HSJS3_k127_8063167_5 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.000000000000000000000000000000000000000000000007882 177.0
HSJS3_k127_8067049_0 Dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 554.0
HSJS3_k127_8067049_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 516.0
HSJS3_k127_8067049_10 uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000009051 220.0
HSJS3_k127_8067049_11 chemotaxis protein K02660 - - 0.000000000000000000000000000000000000000000000002516 177.0
HSJS3_k127_8067049_12 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000000000000000000000004897 170.0
HSJS3_k127_8067049_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 496.0
HSJS3_k127_8067049_3 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K15578 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 463.0
HSJS3_k127_8067049_4 ABC-type nitrate sulfonate bicarbonate transport system, permease component K15577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 464.0
HSJS3_k127_8067049_5 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007879 322.0
HSJS3_k127_8067049_6 Chemotaxis signal transduction protein K02659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002611 257.0
HSJS3_k127_8067049_7 response regulator K02657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008005 243.0
HSJS3_k127_8067049_8 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000001238 237.0
HSJS3_k127_8067049_9 COG0784 FOG CheY-like receiver K02658 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
HSJS3_k127_8096188_0 COG1020 Non-ribosomal peptide synthetase modules and related proteins - - - 1.83e-227 713.0
HSJS3_k127_8096188_1 Sodium:alanine symporter family K03310 - - 8.326e-198 625.0
HSJS3_k127_8096188_2 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 477.0
HSJS3_k127_8096188_3 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 416.0
HSJS3_k127_8096188_5 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000189 150.0
HSJS3_k127_8096188_6 Transport permease protein K01992 - - 0.000000000000000000000000000000001604 129.0
HSJS3_k127_8096188_7 - - - - 0.00000000000000007291 82.0
HSJS3_k127_8096188_8 HD domain K07814 - - 0.00000000000001334 80.0
HSJS3_k127_8143523_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 5.513e-242 792.0
HSJS3_k127_8143523_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 647.0
HSJS3_k127_8143523_2 membrane protein, required for spore maturation in B.subtilis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 490.0
HSJS3_k127_8143523_3 Uncharacterized protein conserved in bacteria (DUF2236) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 475.0
HSJS3_k127_8143523_4 transcriptional regulator K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 380.0
HSJS3_k127_8143523_5 Belongs to the UPF0246 family K09861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 336.0
HSJS3_k127_8143523_6 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 318.0
HSJS3_k127_8143523_7 DNA repair protein - - - 0.000000000000000000000000000000000000000000000000000000007849 204.0
HSJS3_k127_8143523_8 Universal stress protein UspA and related nucleotide-binding K14055 - - 0.0000000000000000000000000000000000000000000000000000001686 206.0
HSJS3_k127_8143523_9 - - - - 0.0000000000000000000000001733 108.0
HSJS3_k127_8206695_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1376.0
HSJS3_k127_8206695_1 Domain related to MnhB subunit of Na+/H+ antiporter K00341,K05559 - 1.6.5.3 0.0 1155.0
HSJS3_k127_8206695_10 Esterase lipase K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 330.0
HSJS3_k127_8206695_11 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 311.0
HSJS3_k127_8206695_12 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 295.0
HSJS3_k127_8206695_14 Sugar-binding cellulase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003079 266.0
HSJS3_k127_8206695_15 COG2863 Cytochrome c553 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006694 242.0
HSJS3_k127_8206695_16 ABC-type Zn2 transport system, periplasmic component surface adhesin K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000001799 234.0
HSJS3_k127_8206695_17 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000001718 203.0
HSJS3_k127_8206695_18 Na H antiporter K05564 - - 0.000000000000000000000000000000000000000002719 159.0
HSJS3_k127_8206695_19 antiporter K05562 - - 0.00000000000000000000000000000000000000005595 160.0
HSJS3_k127_8206695_2 - - - - 9.831e-281 880.0
HSJS3_k127_8206695_20 Subunit C of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K05560 - - 0.000000000000000000000000000000000001945 142.0
HSJS3_k127_8206695_21 COG3245 Cytochrome c5 - - - 0.000000000000000000000000000003555 124.0
HSJS3_k127_8206695_22 COG2212 Multisubunit Na H antiporter, MnhF subunit K05563 - - 0.0000000000000000000000000003249 116.0
HSJS3_k127_8206695_23 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000004401 112.0
HSJS3_k127_8206695_25 Domain of unknown function (DUF4345) - - - 0.0000000001465 68.0
HSJS3_k127_8206695_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 571.0
HSJS3_k127_8206695_4 Deoxyguanosinetriphosphate triphosphohydrolase-like protein K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 540.0
HSJS3_k127_8206695_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005487 481.0
HSJS3_k127_8206695_7 COG3568 Metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 419.0
HSJS3_k127_8206695_8 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006145 422.0
HSJS3_k127_8206695_9 ATPase, AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 375.0
HSJS3_k127_8220709_0 Belongs to the glycosyl hydrolase 31 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 603.0
HSJS3_k127_8220709_1 D-arabinono-1,4-lactone oxidase - - - 0.000000000000000000000000000000000000000002538 169.0
HSJS3_k127_8220709_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000143 124.0
HSJS3_k127_8220709_3 Periplasmic component of amino acid ABC-type transporter signal transduction system - - - 0.000000000000002027 87.0
HSJS3_k127_8272249_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 602.0
HSJS3_k127_8272249_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 466.0
HSJS3_k127_8272249_2 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 359.0
HSJS3_k127_8272249_3 Belongs to the ComB family K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000000000000000000006264 234.0
HSJS3_k127_8272249_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000001465 220.0
HSJS3_k127_8272249_6 Competence protein - - - 0.000000000000000000000000000000000000001824 155.0
HSJS3_k127_8272249_7 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000006617 137.0
HSJS3_k127_8275263_0 flavoprotein involved in K transport - - - 1.531e-203 646.0
HSJS3_k127_8275263_1 COG0514 Superfamily II DNA helicase K03654 - 3.6.4.12 3.065e-199 627.0
HSJS3_k127_8275263_2 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 6.108e-198 629.0
HSJS3_k127_8275263_3 transporter K12942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 577.0
HSJS3_k127_8275263_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 369.0
HSJS3_k127_8275263_5 nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000004984 214.0
HSJS3_k127_8275263_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000001182 138.0
HSJS3_k127_8275263_7 MAPEG family - - - 0.0000000000000000000000000002885 119.0
HSJS3_k127_8277437_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1301.0
HSJS3_k127_8277437_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.002e-236 735.0
HSJS3_k127_8277437_2 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 363.0
HSJS3_k127_8277437_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000004665 157.0
HSJS3_k127_8295036_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0 1201.0
HSJS3_k127_8295036_1 AraC family transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 521.0
HSJS3_k127_8295036_10 MATE efflux family protein K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003772 266.0
HSJS3_k127_8295036_11 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000000000000000000000000000002379 201.0
HSJS3_k127_8295036_12 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000006033 171.0
HSJS3_k127_8295036_13 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000001505 154.0
HSJS3_k127_8295036_14 Sulfur carrier protein TusA K04085 - - 0.000000000000000000000000004843 115.0
HSJS3_k127_8295036_15 mRNA catabolic process - - - 0.0000000000000000000001068 107.0
HSJS3_k127_8295036_2 Metal-dependent hydrolase K07044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 474.0
HSJS3_k127_8295036_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 467.0
HSJS3_k127_8295036_4 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 430.0
HSJS3_k127_8295036_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 398.0
HSJS3_k127_8295036_6 COG0530 Ca2 Na antiporter K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 341.0
HSJS3_k127_8295036_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily K06968 - 2.1.1.186 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 316.0
HSJS3_k127_8295036_8 COG0302 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 286.0
HSJS3_k127_8295036_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000101 278.0
HSJS3_k127_8324202_0 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 492.0
HSJS3_k127_8324202_1 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 396.0
HSJS3_k127_8324202_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003626 251.0
HSJS3_k127_8324202_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000005629 232.0
HSJS3_k127_8371371_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.198e-288 890.0
HSJS3_k127_8371371_1 COG0826 Collagenase and related proteases K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 1.33e-204 647.0
HSJS3_k127_8371371_10 - - - - 0.0006493 49.0
HSJS3_k127_8371371_11 LamG-like jellyroll fold domain - - - 0.0007277 53.0
HSJS3_k127_8371371_2 Protein of unknown function (DUF3592) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 539.0
HSJS3_k127_8371371_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 521.0
HSJS3_k127_8371371_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000005616 209.0
HSJS3_k127_8371371_5 with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000001458 219.0
HSJS3_k127_8371371_6 membrane protein (homolog of Drosophila rhomboid) - - - 0.00000000000000000000000000000000000000000000000001685 189.0
HSJS3_k127_8371371_7 - - - - 0.000000000000000000000000000000000000000001361 179.0
HSJS3_k127_8371371_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000000004509 154.0
HSJS3_k127_8371371_9 - - - - 0.0000000000000000000000000004138 122.0
HSJS3_k127_8376907_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 601.0
HSJS3_k127_8376907_1 unusual protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 563.0
HSJS3_k127_8376907_2 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 522.0
HSJS3_k127_8376907_3 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 458.0
HSJS3_k127_8376907_4 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 455.0
HSJS3_k127_8376907_5 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 405.0
HSJS3_k127_8376907_6 reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 391.0
HSJS3_k127_8376907_7 haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 285.0
HSJS3_k127_8383259_0 2-oxoglutarate dehydrogenase K00164 - 1.2.4.2 0.0 1675.0
HSJS3_k127_8383259_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 0.0 1065.0
HSJS3_k127_8383259_10 Belongs to the small heat shock protein (HSP20) family K04080 - - 0.00000000000000000000000000000000000000000000000000000007307 198.0
HSJS3_k127_8383259_11 succinate dehydrogenase K00241 - - 0.000000000000000000000000000000000000000000000000000002036 206.0
HSJS3_k127_8383259_12 Membrane-anchoring subunit of succinate dehydrogenase (SDH) K00242 - - 0.000000000000000000000000000000000000000000000000001488 186.0
HSJS3_k127_8383259_13 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 GO:0003674,GO:0003824,GO:0004731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016154,GO:0016740,GO:0016757,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.1,2.4.2.2 0.00000000000000000000000000000002158 129.0
HSJS3_k127_8383259_14 Sensors of blue-light using FAD - - - 0.000000000000003539 82.0
HSJS3_k127_8383259_15 Lyase and sodium transporter K01573 - 4.1.1.3 0.000000003148 62.0
HSJS3_k127_8383259_2 Oxaloacetate decarboxylase K01571 - 4.1.1.3 2.155e-284 884.0
HSJS3_k127_8383259_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.757e-260 807.0
HSJS3_k127_8383259_4 Na transporting methylmalonyl-CoA oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 1.222e-216 679.0
HSJS3_k127_8383259_5 Gluconolactonase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 490.0
HSJS3_k127_8383259_6 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 GO:0003674,GO:0003824,GO:0004149,GO:0005488,GO:0005504,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0008289,GO:0009060,GO:0009987,GO:0015980,GO:0016417,GO:0016740,GO:0016746,GO:0016747,GO:0016748,GO:0016751,GO:0016999,GO:0017144,GO:0019752,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0043167,GO:0043168,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045333,GO:0048037,GO:0050662,GO:0055114,GO:0071704,GO:0072350,GO:0097159,GO:0140096,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 492.0
HSJS3_k127_8383259_7 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 467.0
HSJS3_k127_8383259_8 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 404.0
HSJS3_k127_8383259_9 2-oxoglutarate dehydrogenase complex K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 337.0
HSJS3_k127_8399264_0 HemY domain protein - - - 0.0 1243.0
HSJS3_k127_8399264_1 MAPEG family - - - 0.0000000000000000000000000000000000000000000000000000001995 194.0
HSJS3_k127_8399264_2 Peptidase family M20/M25/M40 - - - 0.000000000000000000000000000000000000000000003029 164.0
HSJS3_k127_8437879_0 Histidine kinase K07636 - 2.7.13.3 3.066e-204 642.0
HSJS3_k127_8437879_1 Pyridine nucleotide-disulphide oxidoreductase K05297 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0015046,GO:0016491,GO:0016730,GO:0016731,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.18.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 546.0
HSJS3_k127_8437879_10 Major intrinsic protein - - - 0.00000000000000000000000000000000000000000000000000000000009147 212.0
HSJS3_k127_8437879_11 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000004508 205.0
HSJS3_k127_8437879_12 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000000000000000000006764 201.0
HSJS3_k127_8437879_13 - - - - 0.000000000000000000000000000000000000000000000000201 179.0
HSJS3_k127_8437879_14 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.0000000000000000000000000000000000000000001609 166.0
HSJS3_k127_8437879_15 - - - - 0.0000000000000000000000000000000002777 136.0
HSJS3_k127_8437879_16 rubredoxin - - - 0.0000000000000000000000000000009888 123.0
HSJS3_k127_8437879_17 Transcriptional K03892 - - 0.00000000000000000000000000003246 119.0
HSJS3_k127_8437879_18 Belongs to the SlyX family K03745 - - 0.00000000000003626 76.0
HSJS3_k127_8437879_2 Phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 511.0
HSJS3_k127_8437879_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 481.0
HSJS3_k127_8437879_4 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 417.0
HSJS3_k127_8437879_5 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 417.0
HSJS3_k127_8437879_6 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 388.0
HSJS3_k127_8437879_7 COG1108 ABC-type Mn2 Zn2 transport systems, permease components K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007099 341.0
HSJS3_k127_8437879_8 Lysine methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 310.0
HSJS3_k127_8437879_9 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002229 247.0
HSJS3_k127_8478280_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 387.0
HSJS3_k127_8478280_1 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000007586 199.0
HSJS3_k127_8478280_2 MFS transporter - - - 0.0000000000000000000000005878 104.0
HSJS3_k127_8596591_0 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 573.0
HSJS3_k127_8596591_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 471.0
HSJS3_k127_8596591_2 Saccharopine dehydrogenase NADP binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003859 406.0
HSJS3_k127_8596591_3 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 381.0
HSJS3_k127_8644327_0 Secretory lipase - - - 2.344e-260 816.0
HSJS3_k127_8644327_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 484.0
HSJS3_k127_8644327_2 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005937 385.0
HSJS3_k127_8644327_3 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.000000000000000000000000000000000000000000004353 165.0
HSJS3_k127_8644327_4 - - - - 0.000000000000000000000004918 109.0
HSJS3_k127_8721140_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.606e-269 837.0
HSJS3_k127_8721140_1 Belongs to the GARS family K01945 - 6.3.4.13 1.475e-222 697.0
HSJS3_k127_8721140_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 513.0
HSJS3_k127_8721140_3 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 499.0
HSJS3_k127_8721140_4 Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters K03557 - - 0.00000000000000000000000000000000000000001277 154.0
HSJS3_k127_8721140_5 diguanylate cyclase - - - 0.000000000000000005636 97.0
HSJS3_k127_8769198_0 phosphotransferase related to Ser Thr protein K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 441.0
HSJS3_k127_8769198_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 384.0
HSJS3_k127_8769198_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 325.0
HSJS3_k127_8769198_3 PFAM Nucleotidyl transferase K00992 - 2.7.7.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 311.0
HSJS3_k127_8769198_4 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000008747 225.0
HSJS3_k127_8769198_5 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000004279 112.0
HSJS3_k127_8790559_0 hydroxymethylglutaryl-CoA reductase K00021 - 1.1.1.34 1.937e-198 625.0
HSJS3_k127_8790559_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 509.0
HSJS3_k127_8790559_2 Zinc-binding dehydrogenase K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 304.0
HSJS3_k127_8790559_3 START domain - - - 0.000000000000000000000000000000000000000000000000000000000000002131 226.0
HSJS3_k127_8790559_4 iron-sulfur cluster insertion protein erpA K15724 - - 0.00000000000000000000000000000000000000000000000001068 182.0
HSJS3_k127_8790559_5 COG0671 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000003742 184.0
HSJS3_k127_8790559_6 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000000000000000004422 180.0
HSJS3_k127_8790559_7 - - - - 0.0000000000000000000000000000000000000000000001964 177.0
HSJS3_k127_8790559_8 Cache domain K19694 - - 0.0000000000003407 80.0
HSJS3_k127_8790559_9 - - - - 0.0002651 49.0
HSJS3_k127_8879753_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta K01969 - 6.4.1.4 8.681e-294 908.0
HSJS3_k127_8879753_1 COG2303 Choline dehydrogenase and related flavoproteins - - - 1.326e-235 739.0
HSJS3_k127_8879753_10 exporters of the RND superfamily K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001869 274.0
HSJS3_k127_8879753_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 272.0
HSJS3_k127_8879753_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000005132 223.0
HSJS3_k127_8879753_13 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000001498 224.0
HSJS3_k127_8879753_14 Thioesterase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002697 222.0
HSJS3_k127_8879753_15 Transcriptional - - - 0.00000000000000000000000000000000000000000000000009743 179.0
HSJS3_k127_8879753_16 Acyl-CoA-binding protein - - - 0.0000000000000000000000000000000000000777 143.0
HSJS3_k127_8879753_2 oxidoreductase - - - 1e-233 733.0
HSJS3_k127_8879753_3 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 7.317e-227 721.0
HSJS3_k127_8879753_4 Catalyzes the formation of 3-methylbut-2-enoyl CoA from 3-methylbutanoyl CoA K00253 - 1.3.8.4 5.636e-216 677.0
HSJS3_k127_8879753_5 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 9.813e-205 656.0
HSJS3_k127_8879753_6 ATP-dependent helicase HrpB K03579 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 625.0
HSJS3_k127_8879753_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 494.0
HSJS3_k127_8879753_8 enoyl-CoA hydratase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007755 327.0
HSJS3_k127_8914176_0 FAD linked oxidase - - - 9.361e-246 765.0
HSJS3_k127_8914176_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 1.152e-220 692.0
HSJS3_k127_8914176_2 Fatty acid desaturase K00496 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 9.904e-204 639.0
HSJS3_k127_8914176_3 Fatty acid desaturase K00496 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 550.0
HSJS3_k127_8914176_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 431.0
HSJS3_k127_8914176_5 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 419.0
HSJS3_k127_8914176_6 Fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 286.0
HSJS3_k127_8914176_7 Catalyzes the synthesis of activated sulfate K00860,K00958 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002942 271.0
HSJS3_k127_8914176_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001554 254.0
HSJS3_k127_8914176_9 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000001646 153.0
HSJS3_k127_8918037_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1158.0
HSJS3_k127_8918037_1 Oligopeptidase K01414 - 3.4.24.70 0.0 1065.0
HSJS3_k127_8918037_10 epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 318.0
HSJS3_k127_8918037_11 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000426 263.0
HSJS3_k127_8918037_12 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000006182 256.0
HSJS3_k127_8918037_13 Required for nucleoid occlusion (NO) phenomenon, which prevents Z-ring formation and cell division over the nucleoid. Acts as a DNA-associated cell division inhibitor that binds simultaneously chromosomal DNA and FtsZ, and disrupts the assembly of FtsZ polymers. SlmA-DNA-binding sequences (SBS) are dispersed on non-Ter regions of the chromosome, preventing FtsZ polymerization at these regions K05501 GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0000918,GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0007049,GO:0007346,GO:0008150,GO:0009295,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010564,GO:0010948,GO:0010974,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022607,GO:0031323,GO:0031326,GO:0031333,GO:0032271,GO:0032272,GO:0032465,GO:0032466,GO:0032506,GO:0032954,GO:0032955,GO:0042802,GO:0043085,GO:0043087,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043547,GO:0043565,GO:0043590,GO:0044085,GO:0044087,GO:0044093,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045786,GO:0045930,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051252,GO:0051301,GO:0051302,GO:0051336,GO:0051345,GO:0051726,GO:0051782,GO:0060255,GO:0061640,GO:0065007,GO:0065009,GO:0071840,GO:0080090,GO:0090529,GO:0097159,GO:0140110,GO:1901363,GO:1901891,GO:1901892,GO:1902410,GO:1902412,GO:1902413,GO:1903047,GO:1903436,GO:1903437,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000006315 250.0
HSJS3_k127_8918037_14 Nucleoside 2-deoxyribosyltransferase YtoQ - - - 0.000000000000000000000000000000000000000000000000000000000000000499 222.0
HSJS3_k127_8918037_15 endoribonuclease - - - 0.00000000000000000000000000000000000000000000000000000001058 206.0
HSJS3_k127_8918037_16 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000003912 145.0
HSJS3_k127_8918037_17 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000000001195 138.0
HSJS3_k127_8918037_18 nucleic-acid-binding protein containing a Zn-ribbon domain K07070 - - 0.0000000000000000008274 89.0
HSJS3_k127_8918037_19 - - - - 0.00000000000001368 78.0
HSJS3_k127_8918037_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 1.295e-243 771.0
HSJS3_k127_8918037_20 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.00000000000444 68.0
HSJS3_k127_8918037_21 Belongs to the UPF0758 family K03630 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0006879 45.0
HSJS3_k127_8918037_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 3.398e-220 687.0
HSJS3_k127_8918037_4 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 578.0
HSJS3_k127_8918037_5 transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 499.0
HSJS3_k127_8918037_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930,K22478 - 2.3.1.1,2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 490.0
HSJS3_k127_8918037_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 399.0
HSJS3_k127_8918037_8 stress-induced protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 352.0
HSJS3_k127_8918037_9 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 321.0
HSJS3_k127_8943052_0 Ammonium transporter K03320 - - 6.033e-234 728.0
HSJS3_k127_8943052_1 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 384.0
HSJS3_k127_8943052_2 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006488 380.0
HSJS3_k127_8943052_3 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000597 237.0
HSJS3_k127_8943052_4 START domain - - - 0.00000000000000000000000000000000000000000000009184 177.0
HSJS3_k127_8943052_5 at high nitrogen levels P-II prevents the phosphorylation of NR-I, the transcriptional activator of the glutamine synthetase gene (glnA) K04752 - - 0.0000000000000000000000000001822 114.0
HSJS3_k127_9106350_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 414.0
HSJS3_k127_9106350_1 Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) K08964,K22130 - 4.1.1.104,4.2.1.109 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 290.0
HSJS3_k127_9106350_3 - - - - 0.000000000000000000000000000000000000000001764 163.0
HSJS3_k127_9289219_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.732e-202 637.0
HSJS3_k127_9289219_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 493.0
HSJS3_k127_9289219_10 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000003867 111.0
HSJS3_k127_9289219_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 473.0
HSJS3_k127_9289219_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009042 458.0
HSJS3_k127_9289219_4 peptidase K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 414.0
HSJS3_k127_9289219_5 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 344.0
HSJS3_k127_9289219_6 Maf-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002784 255.0
HSJS3_k127_9289219_7 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K02619 - 4.1.3.38 0.000000000000000000000000000000000000000000000000000000000006157 216.0
HSJS3_k127_9289219_8 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.0000000000000000000000000000000000000000000000001718 181.0
HSJS3_k127_9289219_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000002972 136.0
HSJS3_k127_9367219_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1427.0
HSJS3_k127_9367219_1 Universal stress protein K06149 - - 0.0000000000000000000000000000000000000000000000000000000000001769 218.0
HSJS3_k127_9367219_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.00000000000000000000000000000000000000000000000006971 183.0
HSJS3_k127_9370805_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.175e-216 687.0
HSJS3_k127_9372388_0 Lipoprotein releasing system, transmembrane protein K09808 - - 5.836e-205 643.0
HSJS3_k127_9372388_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 482.0
HSJS3_k127_9372388_2 Belongs to the agmatine deiminase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 442.0
HSJS3_k127_9372388_3 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 291.0
HSJS3_k127_9372388_4 protein conserved in bacteria K09928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001142 249.0
HSJS3_k127_9372388_5 - - - - 0.00000000000000000007644 102.0
HSJS3_k127_9372388_6 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000006346 79.0
HSJS3_k127_9477705_0 Long-chain fatty acid--CoA ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 574.0
HSJS3_k127_9477705_1 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009222 416.0
HSJS3_k127_9477705_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000002271 129.0
HSJS3_k127_9534398_0 Chemotaxis protein histidine kinase and related K02487,K06596 - - 0.0 2545.0
HSJS3_k127_9534398_1 chemotaxis protein K02660 - - 1.715e-280 869.0
HSJS3_k127_9534398_2 Zn-dependent hydrolases of the beta-lactamase fold K13985 - 3.1.4.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009286 511.0
HSJS3_k127_9534398_3 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K06597 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 435.0
HSJS3_k127_9534398_4 COG1352 Methylase of chemotaxis methyl-accepting proteins K00575,K02661 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 431.0
HSJS3_k127_9534398_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000007341 266.0
HSJS3_k127_9534398_6 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000001244 267.0
HSJS3_k127_9534398_7 CheW-like domain K06598 - - 0.000000000000000000000000000000000000000000000000000000000000000002144 229.0
HSJS3_k127_9536195_0 DNA polymerase K02337 - 2.7.7.7 0.0 1748.0
HSJS3_k127_9536195_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 339.0
HSJS3_k127_9536195_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 326.0
HSJS3_k127_9536195_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 GO:0001676,GO:0003674,GO:0003824,GO:0003989,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009317,GO:0009329,GO:0009987,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019752,GO:0032787,GO:0032991,GO:0042759,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576,GO:1902494,GO:1990234 2.1.3.15,6.4.1.2 0.00000003088 57.0
HSJS3_k127_9542739_0 effector of murein hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 299.0
HSJS3_k127_9542739_1 COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1 K03773 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000001507 228.0
HSJS3_k127_9542739_2 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.00000000000000000000000000000000000000000000000000000000000003055 218.0
HSJS3_k127_9542739_3 Belongs to the Rsd AlgQ family K07740 - - 0.0000000000000000000000000000000000000000000000000000004627 197.0
HSJS3_k127_9542739_4 Effector of murein hydrolase LrgA K05338,K06518 GO:0000270,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006810,GO:0008104,GO:0008150,GO:0008152,GO:0008565,GO:0009056,GO:0009057,GO:0009253,GO:0015031,GO:0015833,GO:0016020,GO:0030203,GO:0033036,GO:0042886,GO:0043170,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000002033 127.0
HSJS3_k127_9542739_5 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.000000000000000000000003548 104.0
HSJS3_k127_9563285_0 COG1960 Acyl-CoA dehydrogenases - - - 0.0 1071.0
HSJS3_k127_9563285_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1067.0
HSJS3_k127_9563285_2 can rapidly extrude potassium against a potassium gradient at alkaline pH when cloned and expressed in Escherichia coli K11105 - - 7.291e-212 672.0
HSJS3_k127_9563285_3 Chromosome partitioning K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 469.0
HSJS3_k127_9563285_4 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 456.0
HSJS3_k127_9563285_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000001533 232.0
HSJS3_k127_9583066_0 acyl-CoA dehydrogenase - - - 1.273e-205 657.0
HSJS3_k127_9583066_1 Ammonium Transporter Family K03320 - - 7.075e-199 628.0
HSJS3_k127_9583066_10 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 295.0
HSJS3_k127_9583066_11 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007273 278.0
HSJS3_k127_9583066_12 COG2030 Acyl dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001928 265.0
HSJS3_k127_9583066_13 Appr-1'-p processing enzyme - GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231 - 0.000000000000000000000000000000000000000000000000000000000000000000003625 238.0
HSJS3_k127_9583066_14 Preprotein translocase subunit SecA - - - 0.0000000000000000000000000000000000000000000000000000000000000000005888 232.0
HSJS3_k127_9583066_15 - - - - 0.000000000000000000000000000000000000000002282 164.0
HSJS3_k127_9583066_16 EVE domain - - - 0.000000000000000000000000000000000000000003219 173.0
HSJS3_k127_9583066_17 Protein of unknown function (DUF2505) - - - 0.000000000000000000000000000000000000002692 151.0
HSJS3_k127_9583066_18 Putative prokaryotic signal transducing protein - - - 0.00000000002955 69.0
HSJS3_k127_9583066_2 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 546.0
HSJS3_k127_9583066_3 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 519.0
HSJS3_k127_9583066_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 467.0
HSJS3_k127_9583066_5 exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003922 429.0
HSJS3_k127_9583066_6 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 419.0
HSJS3_k127_9583066_7 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 413.0
HSJS3_k127_9583066_8 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003952 376.0
HSJS3_k127_9583066_9 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 327.0
HSJS3_k127_9766058_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 477.0
HSJS3_k127_9766058_1 COG0084 Mg-dependent DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 329.0
HSJS3_k127_9766058_2 protein conserved in bacteria - - - 0.00000000000000000000000003147 113.0
HSJS3_k127_9766058_3 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000003153 93.0
HSJS3_k127_9766058_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000007259 53.0
HSJS3_k127_9899264_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007281 250.0
HSJS3_k127_9899264_1 transcriptional regulator K03576 - - 0.0000000000000000000000000000000000000000000000000000000000003813 214.0
HSJS3_k127_9899264_2 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000005257 218.0
HSJS3_k127_9899264_3 Domain of unknown function (DUF4279) - - - 0.0000000000000000000000000000000000000000000000000003624 190.0
HSJS3_k127_9899264_4 protein conserved in bacteria K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000002403 186.0
HSJS3_k127_9974955_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006909 507.0
HSJS3_k127_9974955_1 Stringent starvation protein A K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 370.0
HSJS3_k127_9974955_2 Cytochrome c1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 327.0
HSJS3_k127_9974955_3 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 302.0
HSJS3_k127_9974955_4 Stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000001441 154.0