Overview

ID MAG02109
Name LZS1_bin.27
Sample SMP0055
Taxonomy
Kingdom Bacteria
Phylum Patescibacteriota
Class Gracilibacteria
Order UM-FILTER-43-11
Family UM-FILTER-43-11
Genus JAFGTE01
Species
Assembly information
Completeness (%) 99.58
Contamination (%) 0.94
GC content (%) 49.0
N50 (bp) 129,093
Genome size (bp) 1,264,459

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes857

Gene name Description KEGG GOs EC E-value Score Sequence
LZS1_k127_1163363_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 4.104e-310 972.0
LZS1_k127_1163363_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 555.0
LZS1_k127_1163363_10 prephenate dehydrogenase (NADP+) activity K00210,K00211,K00220,K04517,K14187 GO:0000166,GO:0003674,GO:0003824,GO:0004106,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008977,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0070403,GO:0071704,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 1.3.1.12,1.3.1.13,1.3.1.43,5.4.99.5 0.000000000000000000000000000000000000000000000000000000008137 218.0
LZS1_k127_1163363_11 PFAM zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000001791 188.0
LZS1_k127_1163363_12 Prephenate dehydratase K14170 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000001434 172.0
LZS1_k127_1163363_13 YibE F family protein - - - 0.0000000000000000000000000000003487 136.0
LZS1_k127_1163363_14 Alpha-2-macroglobulin family K06894 - - 0.0000000000000000000000000005279 134.0
LZS1_k127_1163363_15 S-layer homology domain - - - 0.00000000000000000006997 107.0
LZS1_k127_1163363_16 Glycogen debranching enzyme K05988 - 3.2.1.11 0.0000000000000000008579 103.0
LZS1_k127_1163363_17 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000009174 78.0
LZS1_k127_1163363_18 Belongs to the Fur family K03711 - - 0.00000000000004363 77.0
LZS1_k127_1163363_19 COG2076 Membrane transporters of cations and cationic drugs K03297 - - 0.0000003609 56.0
LZS1_k127_1163363_2 malic enzyme K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 510.0
LZS1_k127_1163363_20 Cysteine-rich secretory protein family - - - 0.00004828 56.0
LZS1_k127_1163363_21 Lamin Tail Domain - - - 0.0004168 55.0
LZS1_k127_1163363_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 512.0
LZS1_k127_1163363_4 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 425.0
LZS1_k127_1163363_5 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K02823,K17828 GO:0000166,GO:0003674,GO:0003824,GO:0004152,GO:0004158,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0010181,GO:0016020,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0032553,GO:0034641,GO:0034654,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0048037,GO:0050662,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008218 273.0
LZS1_k127_1163363_6 Protein of unknown function (DUF1003) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009049 253.0
LZS1_k127_1163363_7 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008542 245.0
LZS1_k127_1163363_8 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000008635 229.0
LZS1_k127_1163363_9 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000001029 220.0
LZS1_k127_1388534_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1054.0
LZS1_k127_1388534_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 9.303e-304 957.0
LZS1_k127_1388534_10 Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 464.0
LZS1_k127_1388534_11 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 446.0
LZS1_k127_1388534_12 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 429.0
LZS1_k127_1388534_13 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 412.0
LZS1_k127_1388534_14 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into K01875 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 391.0
LZS1_k127_1388534_15 to multidrug resistance ABC transporter ATP-binding protein K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 397.0
LZS1_k127_1388534_16 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004367 386.0
LZS1_k127_1388534_17 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 381.0
LZS1_k127_1388534_18 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 379.0
LZS1_k127_1388534_19 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 371.0
LZS1_k127_1388534_2 ATP-grasp domain - - - 7.369e-242 772.0
LZS1_k127_1388534_20 secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 353.0
LZS1_k127_1388534_21 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 344.0
LZS1_k127_1388534_22 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 336.0
LZS1_k127_1388534_23 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 351.0
LZS1_k127_1388534_24 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 344.0
LZS1_k127_1388534_25 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 311.0
LZS1_k127_1388534_26 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002734 281.0
LZS1_k127_1388534_27 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001361 287.0
LZS1_k127_1388534_28 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002747 271.0
LZS1_k127_1388534_29 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000004705 260.0
LZS1_k127_1388534_3 Belongs to the ClpA ClpB family K03696 - - 1.512e-241 774.0
LZS1_k127_1388534_30 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001448 259.0
LZS1_k127_1388534_31 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000116 248.0
LZS1_k127_1388534_32 pfkB family carbohydrate kinase K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000001999 249.0
LZS1_k127_1388534_33 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
LZS1_k127_1388534_34 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000002508 240.0
LZS1_k127_1388534_35 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000534 241.0
LZS1_k127_1388534_36 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000003844 242.0
LZS1_k127_1388534_37 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
LZS1_k127_1388534_38 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000004866 225.0
LZS1_k127_1388534_39 Hep Hag repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000005254 253.0
LZS1_k127_1388534_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 4.219e-219 699.0
LZS1_k127_1388534_40 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000001635 212.0
LZS1_k127_1388534_41 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000002088 211.0
LZS1_k127_1388534_42 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000009372 198.0
LZS1_k127_1388534_43 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000002566 193.0
LZS1_k127_1388534_44 glycosyl transferase K12994 - 2.4.1.349 0.0000000000000000000000000000000000000000000000000003935 198.0
LZS1_k127_1388534_45 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000009334 188.0
LZS1_k127_1388534_46 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000009901 188.0
LZS1_k127_1388534_47 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000001387 184.0
LZS1_k127_1388534_48 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000009527 177.0
LZS1_k127_1388534_49 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000001456 182.0
LZS1_k127_1388534_5 Adenosylhomocysteinase activity. It is involved in the biological process described with one-carbon metabolic process K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005507,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0032259,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043621,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0046872,GO:0046914,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 9.127e-205 644.0
LZS1_k127_1388534_50 PFAM VanW like protein - - - 0.0000000000000000000000000000000000000000000001916 184.0
LZS1_k127_1388534_51 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000004691 178.0
LZS1_k127_1388534_52 dUTP diphosphatase activity K01520,K13038 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0022607,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0051259,GO:0051260,GO:0055086,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23,4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000003442 167.0
LZS1_k127_1388534_53 PDZ domain (Also known as DHR or GLGF) - - - 0.0000000000000000000000000000000000000000002454 169.0
LZS1_k127_1388534_54 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000002323 157.0
LZS1_k127_1388534_55 YceI-like domain - - - 0.0000000000000000000000000000000000001024 150.0
LZS1_k127_1388534_56 protein histidine kinase activity K11383 - 2.7.13.3 0.0000000000000000000000000000000000001252 155.0
LZS1_k127_1388534_57 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000495 143.0
LZS1_k127_1388534_58 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.00000000000000000000000000000000007713 141.0
LZS1_k127_1388534_59 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070930,GO:0071704,GO:1901564 - 0.00000000000000000000000000000000008774 138.0
LZS1_k127_1388534_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 610.0
LZS1_k127_1388534_60 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000001634 126.0
LZS1_k127_1388534_61 aminopeptidase activity - - - 0.000000000000000000000000002391 132.0
LZS1_k127_1388534_62 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.00000000000000000000000004665 109.0
LZS1_k127_1388534_63 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.000000000000000000000001247 108.0
LZS1_k127_1388534_64 RNHCP domain - - - 0.000000000000000000000004108 104.0
LZS1_k127_1388534_65 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000002393 108.0
LZS1_k127_1388534_66 PFAM Bacterial Ig-like domain (group 2) - - - 0.00000000000000000000005593 113.0
LZS1_k127_1388534_67 transmembrane transporter activity K08166,K08170 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000002428 100.0
LZS1_k127_1388534_68 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000002099 94.0
LZS1_k127_1388534_69 Transcriptional regulator K07665 - - 0.0000000000000002649 83.0
LZS1_k127_1388534_7 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001803 602.0
LZS1_k127_1388534_70 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.00000000000001361 85.0
LZS1_k127_1388534_71 - - - - 0.00000000000001444 79.0
LZS1_k127_1388534_72 HAD-hyrolase-like - - - 0.0000000000003462 79.0
LZS1_k127_1388534_73 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000001119 74.0
LZS1_k127_1388534_74 peptidyl-tyrosine sulfation - - - 0.00000000002158 76.0
LZS1_k127_1388534_75 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000003704 64.0
LZS1_k127_1388534_76 Ion channel - - - 0.00000005499 62.0
LZS1_k127_1388534_77 - - - - 0.0000001632 53.0
LZS1_k127_1388534_78 Sugar-specific transcriptional regulator TrmB - - - 0.0000003494 61.0
LZS1_k127_1388534_79 TPR repeat - - - 0.0000006146 59.0
LZS1_k127_1388534_8 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008771 492.0
LZS1_k127_1388534_80 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000002909 51.0
LZS1_k127_1388534_81 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000009408 54.0
LZS1_k127_1388534_82 HAT (Half-A-TPR) repeats - - - 0.00006128 52.0
LZS1_k127_1388534_83 DUF167 K09131 - - 0.0002075 48.0
LZS1_k127_1388534_84 Methyltransferase domain - - - 0.0002248 53.0
LZS1_k127_1388534_86 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0002645 47.0
LZS1_k127_1388534_87 RelB antitoxin - - - 0.0004679 46.0
LZS1_k127_1388534_88 YtxH-like protein - - - 0.0007284 46.0
LZS1_k127_1388534_9 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000303 489.0
LZS1_k127_1388726_0 histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 383.0
LZS1_k127_1388726_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000008384 173.0
LZS1_k127_1388726_2 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000009494 166.0
LZS1_k127_1388726_3 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000009521 151.0
LZS1_k127_1388726_4 Fibronectin type III domain protein - - - 0.0000000003499 71.0
LZS1_k127_1388726_5 Bacterial Ig-like domain 2 - - - 0.00000007998 66.0
LZS1_k127_1388726_6 - - - - 0.0001222 46.0
LZS1_k127_2164890_0 unfolded protein binding K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0018995,GO:0019219,GO:0019222,GO:0020003,GO:0022607,GO:0030430,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0033643,GO:0033646,GO:0033655,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043531,GO:0043656,GO:0043657,GO:0043933,GO:0044085,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0065010,GO:0070887,GO:0071310,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 4.378e-255 801.0
LZS1_k127_2164890_1 Cation transporter/ATPase, N-terminus - - - 1.208e-248 799.0
LZS1_k127_2164890_10 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 413.0
LZS1_k127_2164890_101 PFAM S23 ribosomal protein - - - 0.000000008568 62.0
LZS1_k127_2164890_102 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000009308 67.0
LZS1_k127_2164890_103 chlorophyll binding K16191,K20276 - - 0.00000001275 66.0
LZS1_k127_2164890_104 Xylose isomerase-like TIM barrel - - - 0.00000001523 64.0
LZS1_k127_2164890_105 Resolvase - - - 0.00000004705 55.0
LZS1_k127_2164890_107 Ribosomal protein L34 K02914 - - 0.00000008619 54.0
LZS1_k127_2164890_108 - - - - 0.0000001054 54.0
LZS1_k127_2164890_11 iron hydrogenase, small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 413.0
LZS1_k127_2164890_110 Protein of unknown function (DUF1573) - - - 0.0000002825 59.0
LZS1_k127_2164890_112 - - - - 0.0000003583 51.0
LZS1_k127_2164890_113 - - - - 0.0000007645 51.0
LZS1_k127_2164890_116 Domain of unknown function (DUF4445) - - - 0.000001799 55.0
LZS1_k127_2164890_117 - - - - 0.00001273 54.0
LZS1_k127_2164890_118 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00001542 50.0
LZS1_k127_2164890_119 - - - - 0.00006711 46.0
LZS1_k127_2164890_12 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 400.0
LZS1_k127_2164890_121 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0005371 47.0
LZS1_k127_2164890_13 DNA photolyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 398.0
LZS1_k127_2164890_14 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 374.0
LZS1_k127_2164890_15 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 367.0
LZS1_k127_2164890_16 Catalyzes the formation of cyclic 2,3-diphosphoglycerate (cDPG) by formation of an intramolecular phosphoanhydride bond at the expense of ATP K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 369.0
LZS1_k127_2164890_17 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 355.0
LZS1_k127_2164890_18 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 342.0
LZS1_k127_2164890_19 Peptidase family U32 C-terminal domain K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 343.0
LZS1_k127_2164890_2 GTP-binding protein TypA K06207 - - 6.718e-212 674.0
LZS1_k127_2164890_20 Amidohydrolase family K01485 - 3.5.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 311.0
LZS1_k127_2164890_21 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 306.0
LZS1_k127_2164890_22 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001055 281.0
LZS1_k127_2164890_23 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000302 273.0
LZS1_k127_2164890_24 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000168 299.0
LZS1_k127_2164890_25 Catalyzes the rate-limiting step of the oxidative pentose-phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis K00036 GO:0003674,GO:0003824,GO:0004345,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0005996,GO:0006006,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019318,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044281,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000008211 278.0
LZS1_k127_2164890_26 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001038 264.0
LZS1_k127_2164890_27 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003911 265.0
LZS1_k127_2164890_28 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000001037 255.0
LZS1_k127_2164890_29 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000001602 255.0
LZS1_k127_2164890_3 PFAM UvrD REP helicase K03657 - 3.6.4.12 3.923e-202 653.0
LZS1_k127_2164890_30 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001093 247.0
LZS1_k127_2164890_31 amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001111 250.0
LZS1_k127_2164890_32 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007463 252.0
LZS1_k127_2164890_33 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000145 251.0
LZS1_k127_2164890_34 Domain of unknown function (DUF4131) K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000008423 235.0
LZS1_k127_2164890_35 Rhamnose biosynthetic enzyme K12451 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005911,GO:0006139,GO:0006725,GO:0006793,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009225,GO:0009226,GO:0009506,GO:0009812,GO:0009813,GO:0009914,GO:0009966,GO:0009987,GO:0010253,GO:0010280,GO:0010315,GO:0010646,GO:0010817,GO:0010928,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0023051,GO:0030054,GO:0030154,GO:0032502,GO:0033478,GO:0034641,GO:0034654,GO:0042127,GO:0042440,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048583,GO:0048869,GO:0050377,GO:0050789,GO:0050794,GO:0051179,GO:0051234,GO:0051552,GO:0051553,GO:0051554,GO:0051555,GO:0055044,GO:0055086,GO:0060918,GO:0065007,GO:0065008,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617 - 0.000000000000000000000000000000000000000000000000000000000000007795 226.0
LZS1_k127_2164890_36 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000003383 220.0
LZS1_k127_2164890_37 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000004195 215.0
LZS1_k127_2164890_38 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000003111 207.0
LZS1_k127_2164890_39 Cellulose binding domain - - - 0.00000000000000000000000000000000000000000000000000004892 211.0
LZS1_k127_2164890_4 Heavy metal transport detoxification protein K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 608.0
LZS1_k127_2164890_40 COG1651 Protein-disulfide isomerase K21990 - - 0.000000000000000000000000000000000000000000000119 178.0
LZS1_k127_2164890_41 - - - - 0.0000000000000000000000000000000000000000000009395 167.0
LZS1_k127_2164890_42 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000002179 170.0
LZS1_k127_2164890_43 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000001312 162.0
LZS1_k127_2164890_44 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000002248 164.0
LZS1_k127_2164890_45 Phage regulatory protein - - - 0.00000000000000000000000000000000000000002618 158.0
LZS1_k127_2164890_46 Glycosyltransferase, group 4 family K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000002589 160.0
LZS1_k127_2164890_47 PFAM ATP-cone domain protein K05715 - - 0.0000000000000000000000000000000000005833 151.0
LZS1_k127_2164890_48 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000001129 148.0
LZS1_k127_2164890_49 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.000000000000000000000000000000000002252 147.0
LZS1_k127_2164890_5 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 530.0
LZS1_k127_2164890_50 - - - - 0.000000000000000000000000000000000004377 149.0
LZS1_k127_2164890_51 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000008727 136.0
LZS1_k127_2164890_52 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000001018 145.0
LZS1_k127_2164890_53 DUF218 domain K03748 - - 0.0000000000000000000000000000001297 131.0
LZS1_k127_2164890_54 PKD domain - - - 0.0000000000000000000000000000002311 145.0
LZS1_k127_2164890_55 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000001769 130.0
LZS1_k127_2164890_56 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000002516 127.0
LZS1_k127_2164890_57 - - - - 0.0000000000000000000000000001274 124.0
LZS1_k127_2164890_58 COG0607 Rhodanese-related sulfurtransferase K03151 - 2.8.1.4 0.00000000000000000000000004464 117.0
LZS1_k127_2164890_59 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.00000000000000000000000006753 121.0
LZS1_k127_2164890_6 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 454.0
LZS1_k127_2164890_60 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000111 117.0
LZS1_k127_2164890_61 - - - - 0.00000000000000000000006714 99.0
LZS1_k127_2164890_62 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604,K11175 - 2.1.2.2,2.1.2.9 0.0000000000000000000000932 108.0
LZS1_k127_2164890_63 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000001271 104.0
LZS1_k127_2164890_64 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K17488 - 2.7.6.3,3.5.4.39 0.0000000000000000000002474 108.0
LZS1_k127_2164890_65 - - - - 0.000000000000000000001336 100.0
LZS1_k127_2164890_66 COG NOG15344 non supervised orthologous group - - - 0.000000000000000000002528 94.0
LZS1_k127_2164890_67 Putative RNA methylase family UPF0020 - - - 0.00000000000000000002013 104.0
LZS1_k127_2164890_68 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000003639 95.0
LZS1_k127_2164890_69 PFAM Divergent PAP2 family K09775 - - 0.00000000000000000008318 94.0
LZS1_k127_2164890_7 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 442.0
LZS1_k127_2164890_70 YGGT family - - - 0.0000000000000000001005 93.0
LZS1_k127_2164890_71 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07775 - - 0.0000000000000000001435 93.0
LZS1_k127_2164890_72 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000007831 91.0
LZS1_k127_2164890_73 - - - - 0.000000000000000002303 86.0
LZS1_k127_2164890_74 Transcriptional regulator, TrmB - - - 0.00000000000000002585 92.0
LZS1_k127_2164890_75 - - - - 0.00000000000000004905 82.0
LZS1_k127_2164890_76 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000005529 86.0
LZS1_k127_2164890_77 - - - - 0.0000000000000002334 80.0
LZS1_k127_2164890_78 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000002844 81.0
LZS1_k127_2164890_8 sulfurtransferase activity K00566 GO:0001510,GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0003824,GO:0004808,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016782,GO:0016783,GO:0030488,GO:0032259,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 436.0
LZS1_k127_2164890_80 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000002455 90.0
LZS1_k127_2164890_82 - - - - 0.000000000000003212 76.0
LZS1_k127_2164890_83 Protein of unknown function (DUF1573) - - - 0.00000000000002276 79.0
LZS1_k127_2164890_84 Metal-sensitive transcriptional repressor K21600 - - 0.00000000000002628 76.0
LZS1_k127_2164890_86 - - - - 0.0000000000001203 76.0
LZS1_k127_2164890_87 Metal-sensitive transcriptional repressor K21600 - - 0.000000000001243 70.0
LZS1_k127_2164890_88 - - - - 0.000000000002068 68.0
LZS1_k127_2164890_89 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000403 73.0
LZS1_k127_2164890_9 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 GO:0003674,GO:0003824,GO:0004616,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006081,GO:0006082,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019362,GO:0019520,GO:0019521,GO:0019637,GO:0019682,GO:0019693,GO:0019752,GO:0032787,GO:0034641,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046176,GO:0046177,GO:0046395,GO:0046483,GO:0046496,GO:0046983,GO:0051156,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072329,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 436.0
LZS1_k127_2164890_90 - - - - 0.00000000000745 66.0
LZS1_k127_2164890_91 Ion transport protein - - - 0.00000000001252 71.0
LZS1_k127_2164890_92 - - - - 0.00000000001369 66.0
LZS1_k127_2164890_93 Major Facilitator Superfamily - - - 0.00000000008089 74.0
LZS1_k127_2164890_94 - - - - 0.00000000009943 68.0
LZS1_k127_2164890_95 - - - - 0.0000000001189 67.0
LZS1_k127_2164890_96 Glucose / Sorbosone dehydrogenase - - - 0.0000000001707 74.0
LZS1_k127_2164890_97 - - - - 0.000000000442 61.0
LZS1_k127_2164890_98 - - - - 0.000000003145 63.0
LZS1_k127_2164890_99 Protein of unknown function (DUF1573) - - - 0.000000004287 66.0
LZS1_k127_3224321_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.678e-254 798.0
LZS1_k127_3325176_0 Class II vitamin B12-dependent ribonucleotide reductase K00525 - 1.17.4.1 0.0 1290.0
LZS1_k127_3325176_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1241.0
LZS1_k127_3325176_10 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.974e-198 631.0
LZS1_k127_3325176_100 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000003216 159.0
LZS1_k127_3325176_101 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000005082 155.0
LZS1_k127_3325176_102 RmuC family K09760 - - 0.0000000000000000000000000000000000000001602 164.0
LZS1_k127_3325176_103 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000002803 154.0
LZS1_k127_3325176_104 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000003173 153.0
LZS1_k127_3325176_105 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000021 148.0
LZS1_k127_3325176_106 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000001145 145.0
LZS1_k127_3325176_107 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000001145 145.0
LZS1_k127_3325176_108 Stage II sporulation K07315 - 3.1.3.3 0.0000000000000000000000000000000000002928 156.0
LZS1_k127_3325176_109 MAP kinase kinase kinase activity - - - 0.0000000000000000000000000000000000006214 156.0
LZS1_k127_3325176_11 UvrD/REP helicase N-terminal domain K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 633.0
LZS1_k127_3325176_110 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000001341 143.0
LZS1_k127_3325176_111 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000782 142.0
LZS1_k127_3325176_112 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000003952 138.0
LZS1_k127_3325176_113 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000005321 136.0
LZS1_k127_3325176_114 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001094 131.0
LZS1_k127_3325176_115 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000000000002823 147.0
LZS1_k127_3325176_116 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000003389 131.0
LZS1_k127_3325176_117 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000001471 132.0
LZS1_k127_3325176_118 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000114 127.0
LZS1_k127_3325176_119 Maf-like protein K06287 - - 0.0000000000000000000000000000001731 130.0
LZS1_k127_3325176_12 Phosphofructokinase K00895,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 534.0
LZS1_k127_3325176_120 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000001382 134.0
LZS1_k127_3325176_121 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000001463 129.0
LZS1_k127_3325176_122 Thioredoxin - - - 0.00000000000000000000000000003707 123.0
LZS1_k127_3325176_123 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000007381 120.0
LZS1_k127_3325176_124 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000004537 115.0
LZS1_k127_3325176_125 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000009619 124.0
LZS1_k127_3325176_126 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000001195 108.0
LZS1_k127_3325176_127 Outer membrane lipoprotein - - - 0.0000000000000000000000004175 116.0
LZS1_k127_3325176_128 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000004706 110.0
LZS1_k127_3325176_129 O-methyltransferase - - - 0.0000000000000000000000006507 111.0
LZS1_k127_3325176_13 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 548.0
LZS1_k127_3325176_130 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000000000000000003595 121.0
LZS1_k127_3325176_131 cell wall surface anchor family protein - - - 0.00000000000000000000005068 115.0
LZS1_k127_3325176_132 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001212 100.0
LZS1_k127_3325176_133 5'-nucleotidase, C-terminal domain K01081,K08693,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.0000000000000000000001272 114.0
LZS1_k127_3325176_134 response regulator - - - 0.0000000000000000000003629 100.0
LZS1_k127_3325176_135 Ribosomal protein L17 K02879 - - 0.0000000000000000000005569 99.0
LZS1_k127_3325176_136 - - - - 0.000000000000000000001925 96.0
LZS1_k127_3325176_137 Belongs to the UPF0102 family K07460 - - 0.000000000000000000009167 95.0
LZS1_k127_3325176_138 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides - - - 0.00000000000000000001092 107.0
LZS1_k127_3325176_139 nucleotidyltransferase activity - - - 0.00000000000000000001449 106.0
LZS1_k127_3325176_14 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 GO:0003674,GO:0003678,GO:0003724,GO:0003824,GO:0004003,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006807,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0008186,GO:0009314,GO:0009379,GO:0009628,GO:0009987,GO:0010501,GO:0016020,GO:0016043,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051276,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360,GO:1902494 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005899 541.0
LZS1_k127_3325176_140 Spore coat protein CotH - - - 0.00000000000000000001844 108.0
LZS1_k127_3325176_141 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000003315 96.0
LZS1_k127_3325176_142 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000006287 94.0
LZS1_k127_3325176_143 response regulator, receiver - - - 0.0000000000000000006669 91.0
LZS1_k127_3325176_144 S-layer homology domain - - - 0.000000000000000002294 97.0
LZS1_k127_3325176_145 S-layer homology domain - - - 0.000000000000000004058 103.0
LZS1_k127_3325176_146 Adenylyl cyclase K05873 - 4.6.1.1 0.000000000000000005404 90.0
LZS1_k127_3325176_147 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000007726 98.0
LZS1_k127_3325176_148 HD domain - - - 0.00000000000000001558 93.0
LZS1_k127_3325176_149 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000003644 83.0
LZS1_k127_3325176_15 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 526.0
LZS1_k127_3325176_150 Sh3 type 3 domain protein K01227,K07260,K13714,K13731 - 3.2.1.96,3.4.17.14,3.5.1.28 0.00000000000000004237 96.0
LZS1_k127_3325176_151 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000006875 82.0
LZS1_k127_3325176_152 Radical SAM domain protein - - - 0.0000000000000001348 94.0
LZS1_k127_3325176_153 Fic/DOC family - - - 0.0000000000000003616 90.0
LZS1_k127_3325176_154 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000001142 80.0
LZS1_k127_3325176_155 PFAM Bacterial Ig-like domain (group 2) - - - 0.000000000000002609 92.0
LZS1_k127_3325176_156 Peptidoglycan-binding LysM - - - 0.000000000000003808 90.0
LZS1_k127_3325176_157 PFAM VanW like protein - - - 0.000000000000007459 87.0
LZS1_k127_3325176_158 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000129 73.0
LZS1_k127_3325176_159 amidohydrolase K01686,K07045 - 4.2.1.8 0.0000000000007176 80.0
LZS1_k127_3325176_16 Fic/DOC family N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 510.0
LZS1_k127_3325176_160 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000009626 76.0
LZS1_k127_3325176_161 TIR domain - - - 0.000000000002156 72.0
LZS1_k127_3325176_162 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000003739 66.0
LZS1_k127_3325176_163 Staphylococcal nuclease homologues K01174,K07038 - 3.1.31.1 0.00000000002473 69.0
LZS1_k127_3325176_164 Sortase family K07284 - 3.4.22.70 0.0000000001748 70.0
LZS1_k127_3325176_165 - - - - 0.00000000127 63.0
LZS1_k127_3325176_166 Bacterial toxin of type II toxin-antitoxin system, YafQ - - - 0.000000003247 61.0
LZS1_k127_3325176_167 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000004323 61.0
LZS1_k127_3325176_169 PFAM phosphatidate cytidylyltransferase - - - 0.0000001104 61.0
LZS1_k127_3325176_17 alginic acid biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 521.0
LZS1_k127_3325176_170 Resolvase, N terminal domain K07450 - - 0.0000002007 55.0
LZS1_k127_3325176_171 COG1366 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) K06378 - - 0.0000005674 56.0
LZS1_k127_3325176_172 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000009579 59.0
LZS1_k127_3325176_173 translation initiation factor activity - - - 0.000004683 60.0
LZS1_k127_3325176_174 PurA ssDNA and RNA-binding protein - - - 0.000005069 52.0
LZS1_k127_3325176_175 Prokaryotic N-terminal methylation motif K08084,K08085 - - 0.000006082 55.0
LZS1_k127_3325176_176 Protease prsW family - - - 0.000007043 57.0
LZS1_k127_3325176_177 Hep Hag repeat protein K21449 - - 0.00001391 59.0
LZS1_k127_3325176_178 tail collar domain protein K01218,K21449 - 3.2.1.78 0.00001955 59.0
LZS1_k127_3325176_179 PKD domain - - - 0.00004901 57.0
LZS1_k127_3325176_18 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 533.0
LZS1_k127_3325176_180 COG3209 Rhs family protein - - - 0.00004961 52.0
LZS1_k127_3325176_181 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.00005811 52.0
LZS1_k127_3325176_182 COG4972 Tfp pilus assembly protein, ATPase PilM K02662 - - 0.00006274 54.0
LZS1_k127_3325176_183 Protein conserved in bacteria - - - 0.0001093 54.0
LZS1_k127_3325176_184 Domain of unknown function (DUF4215) - - - 0.0001095 55.0
LZS1_k127_3325176_185 Septum formation initiator K13052 - - 0.000144 50.0
LZS1_k127_3325176_187 response regulator receiver K19082 - - 0.0001742 51.0
LZS1_k127_3325176_188 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0002622 49.0
LZS1_k127_3325176_19 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 525.0
LZS1_k127_3325176_190 - - - - 0.0006917 52.0
LZS1_k127_3325176_191 Pfam:N_methyl_2 K02650 - - 0.0009509 49.0
LZS1_k127_3325176_192 Hint domain - - - 0.0009913 49.0
LZS1_k127_3325176_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1217.0
LZS1_k127_3325176_20 Adenosine/AMP deaminase K21053 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 484.0
LZS1_k127_3325176_21 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 487.0
LZS1_k127_3325176_22 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 486.0
LZS1_k127_3325176_23 phosphoribosylformylglycinamidine cyclo-ligase activity K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 471.0
LZS1_k127_3325176_24 6-phosphofructokinase activity K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 464.0
LZS1_k127_3325176_25 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 465.0
LZS1_k127_3325176_26 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008531 457.0
LZS1_k127_3325176_27 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 451.0
LZS1_k127_3325176_28 WD40-like Beta Propeller K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009203 448.0
LZS1_k127_3325176_29 Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first K01939 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004019,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019438,GO:0019637,GO:0019693,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042278,GO:0042451,GO:0042455,GO:0043167,GO:0043168,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 443.0
LZS1_k127_3325176_3 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1070.0
LZS1_k127_3325176_30 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 435.0
LZS1_k127_3325176_31 Belongs to the class I fructose-bisphosphate aldolase family K01623 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 412.0
LZS1_k127_3325176_32 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 398.0
LZS1_k127_3325176_33 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 411.0
LZS1_k127_3325176_34 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 412.0
LZS1_k127_3325176_35 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 404.0
LZS1_k127_3325176_36 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 392.0
LZS1_k127_3325176_37 BRO family, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 363.0
LZS1_k127_3325176_38 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 370.0
LZS1_k127_3325176_39 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004087 366.0
LZS1_k127_3325176_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.288e-294 918.0
LZS1_k127_3325176_40 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 354.0
LZS1_k127_3325176_41 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 354.0
LZS1_k127_3325176_42 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 334.0
LZS1_k127_3325176_43 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 338.0
LZS1_k127_3325176_44 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 336.0
LZS1_k127_3325176_45 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 339.0
LZS1_k127_3325176_46 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 336.0
LZS1_k127_3325176_47 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 331.0
LZS1_k127_3325176_48 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 326.0
LZS1_k127_3325176_49 Phosphohydrolase-associated domain K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 329.0
LZS1_k127_3325176_5 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.833e-243 769.0
LZS1_k127_3325176_50 cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 317.0
LZS1_k127_3325176_51 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 305.0
LZS1_k127_3325176_52 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 300.0
LZS1_k127_3325176_53 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 302.0
LZS1_k127_3325176_54 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 292.0
LZS1_k127_3325176_55 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000055 288.0
LZS1_k127_3325176_56 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001225 287.0
LZS1_k127_3325176_57 alpha,alpha-trehalase activity K01194 - 3.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007051 283.0
LZS1_k127_3325176_58 Methionine aminopeptidase K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000001866 263.0
LZS1_k127_3325176_59 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
LZS1_k127_3325176_6 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.153e-238 752.0
LZS1_k127_3325176_60 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002618 256.0
LZS1_k127_3325176_61 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002649 244.0
LZS1_k127_3325176_62 Belongs to the peptidase S41A family K03797 GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0016787,GO:0019538,GO:0023052,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000274 259.0
LZS1_k127_3325176_63 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000009691 248.0
LZS1_k127_3325176_64 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000006996 237.0
LZS1_k127_3325176_65 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000002826 247.0
LZS1_k127_3325176_66 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 - - 0.00000000000000000000000000000000000000000000000000000000000000002424 237.0
LZS1_k127_3325176_67 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000103 238.0
LZS1_k127_3325176_68 PFAM conserved K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000008132 222.0
LZS1_k127_3325176_69 COG0451 Nucleoside-diphosphate-sugar epimerases K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000411 222.0
LZS1_k127_3325176_7 Belongs to the ABC transporter superfamily - - - 9.063e-212 677.0
LZS1_k127_3325176_70 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000005179 227.0
LZS1_k127_3325176_71 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000008864 214.0
LZS1_k127_3325176_72 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000009292 216.0
LZS1_k127_3325176_73 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001753 213.0
LZS1_k127_3325176_74 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000008772 216.0
LZS1_k127_3325176_75 cell division ATP-binding protein FtsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000001722 210.0
LZS1_k127_3325176_76 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000003244 216.0
LZS1_k127_3325176_77 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07291 - 2.7.8.34 0.000000000000000000000000000000000000000000000000000000002131 207.0
LZS1_k127_3325176_78 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000126 198.0
LZS1_k127_3325176_79 PFAM peptidase S11, D-alanyl-D-alanine carboxypeptidase K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000003731 205.0
LZS1_k127_3325176_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K13832 - 1.1.1.25,4.2.1.10 2.157e-203 644.0
LZS1_k127_3325176_80 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000006645 205.0
LZS1_k127_3325176_81 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000001087 207.0
LZS1_k127_3325176_82 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000006404 203.0
LZS1_k127_3325176_83 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000001888 196.0
LZS1_k127_3325176_84 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000009059 192.0
LZS1_k127_3325176_85 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000003324 199.0
LZS1_k127_3325176_86 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07651 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001499 204.0
LZS1_k127_3325176_87 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000002511 184.0
LZS1_k127_3325176_88 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000006471 181.0
LZS1_k127_3325176_89 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000004478 174.0
LZS1_k127_3325176_9 translation elongation factor activity K02358,K15771 GO:0001666,GO:0001817,GO:0001819,GO:0002791,GO:0002793,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009274,GO:0009275,GO:0009628,GO:0009986,GO:0010035,GO:0010038,GO:0010039,GO:0010339,GO:0016020,GO:0019899,GO:0022610,GO:0030312,GO:0032677,GO:0032757,GO:0032879,GO:0032880,GO:0035375,GO:0035821,GO:0036293,GO:0040007,GO:0042221,GO:0044003,GO:0044068,GO:0044403,GO:0044406,GO:0044419,GO:0044424,GO:0044426,GO:0044444,GO:0044462,GO:0044464,GO:0044650,GO:0044651,GO:0048518,GO:0048522,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050794,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051701,GO:0051704,GO:0051817,GO:0065007,GO:0070201,GO:0070482,GO:0071944,GO:0090087,GO:1903530,GO:1903532,GO:1904951,GO:2000482,GO:2000484 - 1.085e-198 625.0
LZS1_k127_3325176_90 DHH family K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000006442 190.0
LZS1_k127_3325176_91 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000126 175.0
LZS1_k127_3325176_92 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000002771 185.0
LZS1_k127_3325176_93 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000007442 171.0
LZS1_k127_3325176_94 Specifically methylates the N7 position of guanine in position 535 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000000000000000000000000003538 176.0
LZS1_k127_3325176_95 type II secretion system K02653 - - 0.0000000000000000000000000000000000000000000007314 179.0
LZS1_k127_3325176_96 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000001107 180.0
LZS1_k127_3325176_97 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000002869 169.0
LZS1_k127_3325176_98 Histidine kinase - - - 0.000000000000000000000000000000000000000005797 175.0
LZS1_k127_3325176_99 metallopeptidase activity K06402 - - 0.000000000000000000000000000000000000000006429 161.0
LZS1_k127_4627751_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 6.454e-238 748.0
LZS1_k127_4627751_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5.688e-231 729.0
LZS1_k127_4627751_10 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000004045 251.0
LZS1_k127_4627751_11 PFAM Glycosyl K12994 - 2.4.1.349 0.0000000000000000000000000000000000000000000000000000000000001697 226.0
LZS1_k127_4627751_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000001026 207.0
LZS1_k127_4627751_13 Belongs to the V-ATPase proteolipid subunit family K02124 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000187 155.0
LZS1_k127_4627751_14 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000006462 153.0
LZS1_k127_4627751_15 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.0000000000000000000000000000000000008131 144.0
LZS1_k127_4627751_16 C subunit K02119 - - 0.000000000000000000000000000000000001849 151.0
LZS1_k127_4627751_17 Mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000008038 151.0
LZS1_k127_4627751_18 Domain of unknown function (DUF305) - - - 0.000000000000000000000000000001288 126.0
LZS1_k127_4627751_19 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.00000000000000000000000005787 111.0
LZS1_k127_4627751_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.826e-212 668.0
LZS1_k127_4627751_20 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000005698 102.0
LZS1_k127_4627751_21 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009011,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000005659 98.0
LZS1_k127_4627751_22 S-layer homology domain - - - 0.00000000000000000009847 103.0
LZS1_k127_4627751_23 structural constituent of ribosome K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000004606 86.0
LZS1_k127_4627751_24 ATP synthase (F/14-kDa) subunit K02122 - - 0.00000000000001078 78.0
LZS1_k127_4627751_25 Belongs to the UPF0109 family K06960 - - 0.00000000000009435 75.0
LZS1_k127_4627751_26 - - - - 0.0000000000000959 74.0
LZS1_k127_4627751_27 regulatory protein, arsR - - - 0.0000000000001806 74.0
LZS1_k127_4627751_28 O-antigen polymerase K18814 - - 0.0000000000006306 81.0
LZS1_k127_4627751_29 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657 - 2.3.1.57 0.00000001126 64.0
LZS1_k127_4627751_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002922 537.0
LZS1_k127_4627751_31 GDSL-like Lipase/Acylhydrolase - - - 0.0001006 53.0
LZS1_k127_4627751_32 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0003324 50.0
LZS1_k127_4627751_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 412.0
LZS1_k127_4627751_5 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 370.0
LZS1_k127_4627751_6 PFAM type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 368.0
LZS1_k127_4627751_7 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005122 339.0
LZS1_k127_4627751_8 permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 308.0
LZS1_k127_4627751_9 dienelactone hydrolase K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003918 273.0
LZS1_k127_4628745_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.475e-278 879.0
LZS1_k127_4628745_1 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537,K12955 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.8 5.073e-235 757.0
LZS1_k127_4628745_10 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 347.0
LZS1_k127_4628745_11 Starch synthase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 353.0
LZS1_k127_4628745_12 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 342.0
LZS1_k127_4628745_13 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 342.0
LZS1_k127_4628745_14 DNA methylase K00571,K00590,K07319 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 307.0
LZS1_k127_4628745_15 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009544 281.0
LZS1_k127_4628745_16 Belongs to the peptidase S8 family K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002646 282.0
LZS1_k127_4628745_17 L-serine dehydratase K01752 GO:0003674,GO:0003824,GO:0003941,GO:0016829,GO:0016840,GO:0016841 4.3.1.17 0.00000000000000000000000000000000000000000000000000000000000000000001199 244.0
LZS1_k127_4628745_18 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000004645 231.0
LZS1_k127_4628745_19 chorismate binding enzyme K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000007797 236.0
LZS1_k127_4628745_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.131e-216 686.0
LZS1_k127_4628745_20 gtp cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000002236 222.0
LZS1_k127_4628745_21 Uridine 5-monophosphate K13421 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0016036,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042221,GO:0042594,GO:0044424,GO:0044444,GO:0044464,GO:0046686,GO:0050896,GO:0051716,GO:0071496 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000004933 222.0
LZS1_k127_4628745_22 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000001639 215.0
LZS1_k127_4628745_23 Belongs to the glycosyltransferase 26 family K05946 - 2.4.1.187 0.000000000000000000000000000000000000000000000000000003383 200.0
LZS1_k127_4628745_24 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.00000000000000000000000000000000000000000000000000002128 198.0
LZS1_k127_4628745_25 Riboflavin synthase K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.000000000000000000000000000000000000000000000000001198 189.0
LZS1_k127_4628745_26 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.000000000000000000000000000000000000000000000000002613 192.0
LZS1_k127_4628745_27 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000001336 179.0
LZS1_k127_4628745_28 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000004573 190.0
LZS1_k127_4628745_29 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000001191 177.0
LZS1_k127_4628745_3 PFAM glycoside hydrolase 15-related - - - 5.123e-197 633.0
LZS1_k127_4628745_30 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000004814 173.0
LZS1_k127_4628745_31 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000006775 169.0
LZS1_k127_4628745_32 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000004778 170.0
LZS1_k127_4628745_33 cellular manganese ion homeostasis - - - 0.0000000000000000000000000000000000000000001033 164.0
LZS1_k127_4628745_34 Type II secretory pathway K02653 - - 0.0000000000000000000000000000000000000000002191 175.0
LZS1_k127_4628745_35 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000003805 164.0
LZS1_k127_4628745_36 Serine dehydratase beta chain K01752 - 4.3.1.17 0.00000000000000000000000000000000000000001261 162.0
LZS1_k127_4628745_37 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000002672 154.0
LZS1_k127_4628745_38 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000002462 156.0
LZS1_k127_4628745_39 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000003371 149.0
LZS1_k127_4628745_40 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000002009 141.0
LZS1_k127_4628745_41 permease - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000004756 148.0
LZS1_k127_4628745_42 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000003672 138.0
LZS1_k127_4628745_43 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000004259 136.0
LZS1_k127_4628745_44 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000000000004301 136.0
LZS1_k127_4628745_45 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000002952 131.0
LZS1_k127_4628745_46 Belongs to the potassium channel family K04886,K04933 GO:0002791,GO:0003674,GO:0005215,GO:0005216,GO:0005242,GO:0005244,GO:0005249,GO:0005251,GO:0005261,GO:0005267,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008076,GO:0008150,GO:0008324,GO:0009987,GO:0010646,GO:0010817,GO:0012505,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015276,GO:0015318,GO:0015459,GO:0015672,GO:0016020,GO:0016021,GO:0016247,GO:0022803,GO:0022832,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0023051,GO:0030001,GO:0031224,GO:0031226,GO:0032879,GO:0032880,GO:0032991,GO:0034220,GO:0034702,GO:0034703,GO:0034705,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046873,GO:0046883,GO:0050708,GO:0050789,GO:0050794,GO:0050796,GO:0051046,GO:0051049,GO:0051179,GO:0051223,GO:0051234,GO:0055085,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0071804,GO:0071805,GO:0071944,GO:0090087,GO:0090276,GO:0098655,GO:0098660,GO:0098662,GO:0098772,GO:0098796,GO:0098797,GO:0099094,GO:0099106,GO:1902495,GO:1903530,GO:1990351 - 0.00000000000000000000000001344 120.0
LZS1_k127_4628745_47 Belongs to the peptidase S8 family - - - 0.00000000000000000000000002756 122.0
LZS1_k127_4628745_48 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000003875 109.0
LZS1_k127_4628745_49 Sortase family K07284,K22278 - 3.4.22.70,3.5.1.104 0.0000000000000000000000002037 119.0
LZS1_k127_4628745_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 578.0
LZS1_k127_4628745_50 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000009095 113.0
LZS1_k127_4628745_51 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000003727 102.0
LZS1_k127_4628745_52 Ami_3 K01448 - 3.5.1.28 0.0000000000000000006095 100.0
LZS1_k127_4628745_53 Ribosomal protein L31 K02909 - - 0.00000000000000002105 89.0
LZS1_k127_4628745_54 2OG-Fe(II) oxygenase superfamily K10770 GO:0000049,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008198,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016491,GO:0016604,GO:0016705,GO:0016706,GO:0016740,GO:0016741,GO:0030488,GO:0031974,GO:0031981,GO:0032259,GO:0033554,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051213,GO:0051716,GO:0055114,GO:0070013,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.229 0.00000000000000009177 90.0
LZS1_k127_4628745_55 Methionine biosynthesis protein MetW - - - 0.0000000000000001434 87.0
LZS1_k127_4628745_56 S-layer homology domain - - - 0.0000000000000009038 89.0
LZS1_k127_4628745_57 YGGT family K02221 - - 0.0000000000005512 71.0
LZS1_k127_4628745_58 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.00000004023 61.0
LZS1_k127_4628745_59 Domain of unknown function DUF11 - - - 0.00000008044 65.0
LZS1_k127_4628745_6 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 496.0
LZS1_k127_4628745_60 cellulase activity K01361,K07004,K13735,K21571 - 3.4.21.96 0.0000001024 64.0
LZS1_k127_4628745_61 Nhl repeat - - - 0.0000001104 65.0
LZS1_k127_4628745_62 Yip1 domain - - - 0.0000001578 61.0
LZS1_k127_4628745_63 N-acetylmuramoyl-L-alanine amidase - - - 0.000001088 60.0
LZS1_k127_4628745_64 Transglutaminase-like superfamily - - - 0.000003302 57.0
LZS1_k127_4628745_65 general secretion pathway protein G K02456 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0071702,GO:0071705 - 0.000005179 60.0
LZS1_k127_4628745_66 antisigma factor binding K17763 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0035556,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0140096,GO:1901564 - 0.000006962 53.0
LZS1_k127_4628745_67 serine threonine protein kinase - - - 0.00003974 55.0
LZS1_k127_4628745_68 endonuclease activity K07451 - - 0.00005017 54.0
LZS1_k127_4628745_69 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00006212 48.0
LZS1_k127_4628745_7 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 444.0
LZS1_k127_4628745_70 Bacterial PH domain - - - 0.00008575 52.0
LZS1_k127_4628745_71 S-layer homology domain - - - 0.0008231 51.0
LZS1_k127_4628745_8 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 367.0
LZS1_k127_4628745_9 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885,K09698 - 6.1.1.17,6.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 366.0
LZS1_k127_5818100_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 1.38e-297 952.0
LZS1_k127_5818100_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.065e-195 648.0
LZS1_k127_5818100_10 Metallo-beta-lactamase superfamily domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 447.0
LZS1_k127_5818100_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 413.0
LZS1_k127_5818100_12 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 433.0
LZS1_k127_5818100_13 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 405.0
LZS1_k127_5818100_14 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 396.0
LZS1_k127_5818100_15 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 376.0
LZS1_k127_5818100_16 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 371.0
LZS1_k127_5818100_17 Single-stranded-DNA-specific exonuclease recj K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 378.0
LZS1_k127_5818100_18 Poly A polymerase head domain K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 369.0
LZS1_k127_5818100_19 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 363.0
LZS1_k127_5818100_2 GMP synthase (glutamine-hydrolyzing) activity K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034404,GO:0034641,GO:0034654,GO:0040007,GO:0042278,GO:0042451,GO:0042455,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 589.0
LZS1_k127_5818100_20 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 350.0
LZS1_k127_5818100_21 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 320.0
LZS1_k127_5818100_22 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 306.0
LZS1_k127_5818100_23 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 294.0
LZS1_k127_5818100_24 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000003137 278.0
LZS1_k127_5818100_25 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 267.0
LZS1_k127_5818100_26 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000008845 258.0
LZS1_k127_5818100_27 Belongs to the SEDS family K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000005334 252.0
LZS1_k127_5818100_28 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000007904 247.0
LZS1_k127_5818100_29 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000002391 241.0
LZS1_k127_5818100_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007877 551.0
LZS1_k127_5818100_30 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000007471 222.0
LZS1_k127_5818100_31 Redoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000162 219.0
LZS1_k127_5818100_32 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000000000000000002264 224.0
LZS1_k127_5818100_33 DNA-directed DNA polymerase activity K02347,K04477 - - 0.00000000000000000000000000000000000000000000000000000000000002618 226.0
LZS1_k127_5818100_34 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000139 223.0
LZS1_k127_5818100_35 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000009917 214.0
LZS1_k127_5818100_36 STAS-like domain of unknown function (DUF4325) - - - 0.0000000000000000000000000000000000000000000000000000000002126 215.0
LZS1_k127_5818100_37 - - - - 0.0000000000000000000000000000000000000000000000000000006559 198.0
LZS1_k127_5818100_38 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000004065 204.0
LZS1_k127_5818100_39 Tyrosine recombinase XerD K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000001091 197.0
LZS1_k127_5818100_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 534.0
LZS1_k127_5818100_40 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000001146 194.0
LZS1_k127_5818100_41 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000001165 192.0
LZS1_k127_5818100_42 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000004047 186.0
LZS1_k127_5818100_43 COG1651 Protein-disulfide isomerase K21990 - - 0.00000000000000000000000000000000000000000000003204 178.0
LZS1_k127_5818100_44 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000005457 188.0
LZS1_k127_5818100_45 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000008447 174.0
LZS1_k127_5818100_46 PFAM N-acetylmuramoyl-L-alanine amidase, family 2 - - - 0.00000000000000000000000000000000000000000002055 170.0
LZS1_k127_5818100_47 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000003296 165.0
LZS1_k127_5818100_48 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000002119 164.0
LZS1_k127_5818100_49 N-acetylmuramoyl-L-alanine amidase - - - 0.000000000000000000000000000000000000716 162.0
LZS1_k127_5818100_5 Catalyzes the irreversible beta-carboxylation of phosphoenolpyruvate (PEP) to form oxaloacetate (OAA), a four- carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 520.0
LZS1_k127_5818100_50 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.00000000000000000000000000000000001088 146.0
LZS1_k127_5818100_51 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000833 134.0
LZS1_k127_5818100_52 Glycosyl transferase, family 2 K13500 - 2.4.1.175,2.4.1.226 0.0000000000000000000000000000001067 137.0
LZS1_k127_5818100_53 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000000000000000000000000788 122.0
LZS1_k127_5818100_54 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000000000003016 123.0
LZS1_k127_5818100_55 tRNA (guanine(37)-N(1))-methyltransferase activity - - - 0.0000000000000000000000005531 114.0
LZS1_k127_5818100_56 ATPase or kinase K06925 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000001733 116.0
LZS1_k127_5818100_57 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000002587 117.0
LZS1_k127_5818100_58 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.00000000000000000008023 106.0
LZS1_k127_5818100_59 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000001826 96.0
LZS1_k127_5818100_6 magnesium chelatase K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 495.0
LZS1_k127_5818100_60 cellulase activity - - - 0.0000000000000000005544 106.0
LZS1_k127_5818100_61 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K21515 - 2.1.1.209 0.000000000000000002464 92.0
LZS1_k127_5818100_62 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000001061 97.0
LZS1_k127_5818100_63 Smr domain - - - 0.00000000000000001185 87.0
LZS1_k127_5818100_64 Metallo-beta-lactamase superfamily - - - 0.00000000000000005603 96.0
LZS1_k127_5818100_65 riboflavin biosynthesis protein K11753 - 2.7.1.26,2.7.7.2 0.0000000000000004062 82.0
LZS1_k127_5818100_66 histidine kinase HAMP region domain protein - - - 0.0000000000000006426 89.0
LZS1_k127_5818100_67 Carboxypeptidase - - - 0.00000000000001398 91.0
LZS1_k127_5818100_68 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000005595 78.0
LZS1_k127_5818100_69 S-layer homology domain - - - 0.0000000000009766 79.0
LZS1_k127_5818100_7 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007936 488.0
LZS1_k127_5818100_70 LamG domain protein jellyroll fold domain protein K03418,K07151 - 2.4.99.18,3.5.1.56 0.000000000007615 82.0
LZS1_k127_5818100_71 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000001263 73.0
LZS1_k127_5818100_72 Stage II sporulation protein D K06381 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.00000000002271 78.0
LZS1_k127_5818100_73 regulator of chromosome condensation, RCC1 - - - 0.00000000002278 81.0
LZS1_k127_5818100_74 -O-antigen K02847 - - 0.00000001296 67.0
LZS1_k127_5818100_75 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000001394 66.0
LZS1_k127_5818100_76 - - - - 0.00000829 58.0
LZS1_k127_5818100_77 response regulator - - - 0.000008623 55.0
LZS1_k127_5818100_78 cellulase activity - - - 0.00002021 61.0
LZS1_k127_5818100_8 Ferredoxin-fold anticodon binding domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000536 494.0
LZS1_k127_5818100_80 - - - - 0.00002735 50.0
LZS1_k127_5818100_81 RF-1 domain K15034 - - 0.00006941 51.0
LZS1_k127_5818100_82 TIGRFAM RHS repeat-associated core domain - - - 0.0001046 59.0
LZS1_k127_5818100_83 - - - - 0.0004893 51.0
LZS1_k127_5818100_9 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 466.0
LZS1_k127_6811621_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.367e-272 862.0
LZS1_k127_6811621_1 Alpha-2-macroglobulin family K06894 - - 1.623e-262 879.0
LZS1_k127_6811621_10 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 394.0
LZS1_k127_6811621_11 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 385.0
LZS1_k127_6811621_12 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 385.0
LZS1_k127_6811621_13 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 368.0
LZS1_k127_6811621_14 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 355.0
LZS1_k127_6811621_15 Type IV secretory pathway, VirB4 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 372.0
LZS1_k127_6811621_16 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 344.0
LZS1_k127_6811621_17 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 297.0
LZS1_k127_6811621_18 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001712 275.0
LZS1_k127_6811621_19 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000009822 246.0
LZS1_k127_6811621_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 6.088e-210 676.0
LZS1_k127_6811621_20 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000001153 235.0
LZS1_k127_6811621_21 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000003133 219.0
LZS1_k127_6811621_22 Sugar-transfer associated ATP-grasp - - - 0.000000000000000000000000000000000000000000000000000000000001512 235.0
LZS1_k127_6811621_23 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000524 212.0
LZS1_k127_6811621_24 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000009703 225.0
LZS1_k127_6811621_25 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000001762 189.0
LZS1_k127_6811621_26 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000004671 195.0
LZS1_k127_6811621_27 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000001835 196.0
LZS1_k127_6811621_28 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000273 168.0
LZS1_k127_6811621_29 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000006291 162.0
LZS1_k127_6811621_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 610.0
LZS1_k127_6811621_30 TIGRFAM F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000002187 155.0
LZS1_k127_6811621_31 Methicillin resistance protein - - - 0.000000000000000000000000000000000006812 148.0
LZS1_k127_6811621_32 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000004207 146.0
LZS1_k127_6811621_33 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000001716 132.0
LZS1_k127_6811621_34 protein conserved in bacteria - - - 0.0000000000000000000000000004883 132.0
LZS1_k127_6811621_35 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.000000000000000000000000004228 119.0
LZS1_k127_6811621_36 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000815 118.0
LZS1_k127_6811621_37 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000003145 115.0
LZS1_k127_6811621_38 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000003523 111.0
LZS1_k127_6811621_39 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000007042 107.0
LZS1_k127_6811621_4 Permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 561.0
LZS1_k127_6811621_41 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000001674 100.0
LZS1_k127_6811621_42 helicase superfamily c-terminal domain - - - 0.0000000000000000000006754 111.0
LZS1_k127_6811621_43 7 transmembrane helices usually fused to an inactive transglutaminase - - - 0.00000000000000000004247 104.0
LZS1_k127_6811621_44 S-layer homology domain - - - 0.0000000000000000806 92.0
LZS1_k127_6811621_45 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000313 77.0
LZS1_k127_6811621_46 protein serine/threonine phosphatase activity - - - 0.00000000001894 77.0
LZS1_k127_6811621_47 - - - - 0.00000000004263 70.0
LZS1_k127_6811621_48 O-Antigen ligase - - - 0.0000000001564 73.0
LZS1_k127_6811621_49 Cold shock protein domain K03704 - - 0.00000000016 64.0
LZS1_k127_6811621_5 tRNA synthetases class II (D, K and N) K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 519.0
LZS1_k127_6811621_50 Thioredoxin - - - 0.0000000006758 70.0
LZS1_k127_6811621_51 restriction endonuclease - - - 0.000000002248 68.0
LZS1_k127_6811621_52 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000522 61.0
LZS1_k127_6811621_53 NYN domain - - - 0.00000001503 63.0
LZS1_k127_6811621_54 protein contain chitin-binding domain type 3 - - - 0.00000003175 66.0
LZS1_k127_6811621_56 TPR repeat - - - 0.0000001052 62.0
LZS1_k127_6811621_57 - - - - 0.000003186 60.0
LZS1_k127_6811621_58 Bacterial toxin of type II toxin-antitoxin system, YafQ K19157 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006415,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016787,GO:0016788,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0034655,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576 - 0.000005323 51.0
LZS1_k127_6811621_59 - - - - 0.00000958 53.0
LZS1_k127_6811621_6 Penicillin-Binding Protein C-terminus Family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 536.0
LZS1_k127_6811621_60 bacterial-type proximal promoter sequence-specific DNA binding K07473 - - 0.00002116 50.0
LZS1_k127_6811621_61 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00002221 51.0
LZS1_k127_6811621_7 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 503.0
LZS1_k127_6811621_8 PFAM ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 494.0
LZS1_k127_6811621_9 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 448.0
LZS1_k127_7631143_0 Carbamoyl-phosphate synthase (glutamine-hydrolyzing) K01955 - 6.3.5.5 0.0 1320.0
LZS1_k127_7631143_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1228.0
LZS1_k127_7631143_10 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000994 472.0
LZS1_k127_7631143_100 5-(carboxyamino)imidazole ribonucleotide synthase activity - - - 0.0000000335 66.0
LZS1_k127_7631143_102 Type II secretion system (T2SS), protein G K02456 - - 0.000000392 59.0
LZS1_k127_7631143_104 Protein of unknown function (DUF3307) - - - 0.000003844 56.0
LZS1_k127_7631143_105 phosphoserine phosphatase K01079 - 3.1.3.3 0.000007753 57.0
LZS1_k127_7631143_106 Nucleotidyltransferase domain - - - 0.000009169 55.0
LZS1_k127_7631143_107 Protease prsW family - - - 0.00001455 56.0
LZS1_k127_7631143_108 Domain of unknown function DUF11 - - - 0.00007719 57.0
LZS1_k127_7631143_11 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 455.0
LZS1_k127_7631143_111 PFAM membrane-flanked domain - - - 0.000156 51.0
LZS1_k127_7631143_112 Belongs to the anti-sigma-factor antagonist family - - - 0.0003162 49.0
LZS1_k127_7631143_113 regulation of DNA repair K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.0004662 49.0
LZS1_k127_7631143_114 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000611 46.0
LZS1_k127_7631143_12 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 458.0
LZS1_k127_7631143_13 Cytochrome C biogenesis protein transmembrane region - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 457.0
LZS1_k127_7631143_14 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 418.0
LZS1_k127_7631143_15 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 412.0
LZS1_k127_7631143_16 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 399.0
LZS1_k127_7631143_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 397.0
LZS1_k127_7631143_18 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 392.0
LZS1_k127_7631143_19 PFAM type II secretion system protein E K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 381.0
LZS1_k127_7631143_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1094.0
LZS1_k127_7631143_20 COG4452 Inner membrane protein involved in colicin E2 resistance K06143 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 377.0
LZS1_k127_7631143_21 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 358.0
LZS1_k127_7631143_22 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 361.0
LZS1_k127_7631143_23 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 355.0
LZS1_k127_7631143_24 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005079 346.0
LZS1_k127_7631143_25 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 345.0
LZS1_k127_7631143_26 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 329.0
LZS1_k127_7631143_27 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 319.0
LZS1_k127_7631143_28 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 322.0
LZS1_k127_7631143_29 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 313.0
LZS1_k127_7631143_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1086.0
LZS1_k127_7631143_30 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 310.0
LZS1_k127_7631143_31 Phosphoglucose isomerase K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 313.0
LZS1_k127_7631143_32 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 297.0
LZS1_k127_7631143_33 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001319 289.0
LZS1_k127_7631143_34 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 273.0
LZS1_k127_7631143_35 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006045 270.0
LZS1_k127_7631143_36 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000008019 271.0
LZS1_k127_7631143_37 PFAM Orn DAP Arg decarboxylase 2 K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000004673 274.0
LZS1_k127_7631143_38 glycerol-3-phosphate catabolic process K00057 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016616,GO:0047952,GO:0055114 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000002897 267.0
LZS1_k127_7631143_39 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000005264 243.0
LZS1_k127_7631143_4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 1.428e-220 717.0
LZS1_k127_7631143_40 Bacterial type II secretion system domain protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000003301 232.0
LZS1_k127_7631143_41 Inhibitor of apoptosis-promoting Bax1 K06890 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
LZS1_k127_7631143_42 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000001447 214.0
LZS1_k127_7631143_43 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000003778 211.0
LZS1_k127_7631143_44 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001147 200.0
LZS1_k127_7631143_45 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000001444 204.0
LZS1_k127_7631143_46 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000000000000000000001717 200.0
LZS1_k127_7631143_47 Nucleoside diphosphate kinase K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000001197 192.0
LZS1_k127_7631143_48 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000996 206.0
LZS1_k127_7631143_49 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000000000000000009091 201.0
LZS1_k127_7631143_5 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.959e-207 663.0
LZS1_k127_7631143_50 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000000000000000000000000000000000000000000000001996 193.0
LZS1_k127_7631143_51 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000004974 182.0
LZS1_k127_7631143_52 Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA K02035 - - 0.000000000000000000000000000000000000000000000001225 193.0
LZS1_k127_7631143_53 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000004255 187.0
LZS1_k127_7631143_54 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000006715 177.0
LZS1_k127_7631143_55 ATP-grasp domain K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000001776 192.0
LZS1_k127_7631143_56 ATP-grasp domain K14755 - 6.3.2.11 0.00000000000000000000000000000000000000000005314 184.0
LZS1_k127_7631143_57 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000615 157.0
LZS1_k127_7631143_58 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000008905 157.0
LZS1_k127_7631143_59 ATP-grasp domain - - - 0.00000000000000000000000000000000000001323 162.0
LZS1_k127_7631143_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 582.0
LZS1_k127_7631143_60 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000000000000006504 156.0
LZS1_k127_7631143_61 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000211 140.0
LZS1_k127_7631143_62 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000001877 140.0
LZS1_k127_7631143_63 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000006903 148.0
LZS1_k127_7631143_64 PFAM Polysaccharide pyruvyl transferase - - - 0.000000000000000000000000000000004613 141.0
LZS1_k127_7631143_65 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000009245 130.0
LZS1_k127_7631143_66 YqeY-like protein K09117 - - 0.000000000000000000000000000021 123.0
LZS1_k127_7631143_67 (GGDEF) domain K13590 - 2.7.7.65 0.00000000000000000000000000004724 129.0
LZS1_k127_7631143_68 HIT domain K02503 - - 0.0000000000000000000000000002434 118.0
LZS1_k127_7631143_69 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000003396 124.0
LZS1_k127_7631143_7 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 576.0
LZS1_k127_7631143_70 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000008909 120.0
LZS1_k127_7631143_71 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000000000001407 117.0
LZS1_k127_7631143_72 Polymer-forming cytoskeletal - - - 0.000000000000000000000000003205 124.0
LZS1_k127_7631143_73 Immunoglobulin-like domain of bacterial spore germination - - - 0.00000000000000000000000002596 119.0
LZS1_k127_7631143_74 Transcriptional regulator - - - 0.00000000000000000000000007343 123.0
LZS1_k127_7631143_75 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000001075 121.0
LZS1_k127_7631143_76 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000001435 113.0
LZS1_k127_7631143_77 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000004219 105.0
LZS1_k127_7631143_78 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000005104 103.0
LZS1_k127_7631143_79 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859,K01734 - 2.7.1.24,4.2.3.3 0.00000000000000000000000597 109.0
LZS1_k127_7631143_8 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 586.0
LZS1_k127_7631143_80 RNA-binding protein - - - 0.0000000000000000000001919 99.0
LZS1_k127_7631143_81 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000327 99.0
LZS1_k127_7631143_82 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000009542 112.0
LZS1_k127_7631143_83 PhnA domain K06193 - - 0.00000000000000000003385 94.0
LZS1_k127_7631143_84 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000003143 94.0
LZS1_k127_7631143_85 Sigma-70, region 4 K03088 - - 0.000000000000000006671 90.0
LZS1_k127_7631143_86 NlpC/P60 family - - - 0.00000000000000001847 97.0
LZS1_k127_7631143_87 cyclic nucleotide binding K04739,K10914 - - 0.00000000000000006197 85.0
LZS1_k127_7631143_88 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000003943 89.0
LZS1_k127_7631143_89 membrane K21471 - - 0.000000000000002061 90.0
LZS1_k127_7631143_9 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000856 533.0
LZS1_k127_7631143_90 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000007078 77.0
LZS1_k127_7631143_91 nuclease activity K06218 - - 0.000000000000007432 77.0
LZS1_k127_7631143_92 protein transport - - - 0.00000000000001189 77.0
LZS1_k127_7631143_93 Protein of unknown function (DUF1361) - - - 0.00000000000001199 82.0
LZS1_k127_7631143_94 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.0000000000003029 83.0
LZS1_k127_7631143_95 transmembrane transport - - - 0.0000000000003793 78.0
LZS1_k127_7631143_97 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000002564 69.0
LZS1_k127_7631143_98 regulatory protein, FmdB family - - - 0.0000000008919 62.0
LZS1_k127_7631143_99 Thioredoxin - - - 0.00000000158 66.0
LZS1_k127_850480_0 isoleucyl-tRNA aminoacylation K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 1.43e-322 1028.0
LZS1_k127_850480_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.015e-202 652.0
LZS1_k127_850480_10 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 429.0
LZS1_k127_850480_11 PFAM Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 399.0
LZS1_k127_850480_12 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 385.0
LZS1_k127_850480_13 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 384.0
LZS1_k127_850480_14 TIGRFAM Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 390.0
LZS1_k127_850480_15 C-5 cytosine-specific DNA methylase K00558 - 2.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 364.0
LZS1_k127_850480_16 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 356.0
LZS1_k127_850480_17 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 302.0
LZS1_k127_850480_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 312.0
LZS1_k127_850480_19 AhpC/TSA family K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 289.0
LZS1_k127_850480_2 Threonine synthase K01733 - 4.2.3.1 2.864e-194 624.0
LZS1_k127_850480_20 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001865 284.0
LZS1_k127_850480_21 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000111 272.0
LZS1_k127_850480_22 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001132 271.0
LZS1_k127_850480_23 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000001554 254.0
LZS1_k127_850480_24 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000001095 245.0
LZS1_k127_850480_25 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000006156 239.0
LZS1_k127_850480_26 Glycosyl Transferase K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000004763 234.0
LZS1_k127_850480_27 Nickel-containing superoxide dismutase K00518 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000002028 223.0
LZS1_k127_850480_28 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000004903 226.0
LZS1_k127_850480_29 Bsp6I restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000002321 219.0
LZS1_k127_850480_3 feS assembly protein SufB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 578.0
LZS1_k127_850480_30 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000002317 205.0
LZS1_k127_850480_31 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000002132 201.0
LZS1_k127_850480_32 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.35 0.0000000000000000000000000000000000000000000000000004589 198.0
LZS1_k127_850480_33 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000708 178.0
LZS1_k127_850480_35 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000008377 176.0
LZS1_k127_850480_36 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000002032 181.0
LZS1_k127_850480_37 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000238 162.0
LZS1_k127_850480_38 Inositol monophosphatase K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.000000000000000000000000000000000000000002097 165.0
LZS1_k127_850480_39 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000002257 171.0
LZS1_k127_850480_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 552.0
LZS1_k127_850480_40 PFAM tRNA rRNA methyltransferase (SpoU) - - - 0.000000000000000000000000000000000000000002808 160.0
LZS1_k127_850480_41 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000001084 161.0
LZS1_k127_850480_42 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000005344 149.0
LZS1_k127_850480_43 Dihydrofolate reductase K00287 GO:0000082,GO:0000083,GO:0000166,GO:0000278,GO:0000900,GO:0001101,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004146,GO:0005488,GO:0005515,GO:0005542,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005829,GO:0006066,GO:0006082,GO:0006139,GO:0006213,GO:0006355,GO:0006417,GO:0006575,GO:0006725,GO:0006729,GO:0006732,GO:0006760,GO:0006766,GO:0006767,GO:0006807,GO:0006950,GO:0007049,GO:0007275,GO:0007399,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009120,GO:0009163,GO:0009396,GO:0009611,GO:0009636,GO:0009889,GO:0009890,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0014070,GO:0016020,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0017144,GO:0017148,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019751,GO:0019752,GO:0019842,GO:0019866,GO:0022008,GO:0022402,GO:0030030,GO:0030154,GO:0030182,GO:0030371,GO:0031090,GO:0031099,GO:0031102,GO:0031103,GO:0031175,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0031427,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032768,GO:0032770,GO:0033218,GO:0033554,GO:0033560,GO:0034248,GO:0034249,GO:0034311,GO:0034312,GO:0034404,GO:0034641,GO:0034654,GO:0035094,GO:0036094,GO:0042221,GO:0042398,GO:0042493,GO:0042558,GO:0042559,GO:0043085,GO:0043167,GO:0043168,GO:0043177,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044843,GO:0045182,GO:0046104,GO:0046105,GO:0046120,GO:0046125,GO:0046126,GO:0046134,GO:0046146,GO:0046165,GO:0046173,GO:0046394,GO:0046452,GO:0046483,GO:0046653,GO:0046654,GO:0046655,GO:0048037,GO:0048468,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048666,GO:0048678,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050661,GO:0050662,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050999,GO:0051000,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051246,GO:0051248,GO:0051252,GO:0051341,GO:0051353,GO:0051716,GO:0051870,GO:0051871,GO:0055086,GO:0055114,GO:0060255,GO:0061564,GO:0065007,GO:0065009,GO:0070013,GO:0070402,GO:0071704,GO:0071840,GO:0072341,GO:0072527,GO:0072528,GO:0080090,GO:0080134,GO:0080135,GO:0090079,GO:0090322,GO:0097159,GO:0097327,GO:0097329,GO:0120036,GO:1900407,GO:1901031,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901657,GO:1901659,GO:1901698,GO:1901700,GO:1902882,GO:1903047,GO:1903506,GO:1990825,GO:2000112,GO:2000113,GO:2000121,GO:2000377,GO:2001141 1.5.1.3 0.0000000000000000000000000000000004107 137.0
LZS1_k127_850480_44 SAICAR synthetase K01588,K01923,K01945,K03566 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18,6.3.2.6,6.3.4.13 0.000000000000000000000000000000001003 135.0
LZS1_k127_850480_45 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000001665 139.0
LZS1_k127_850480_46 SNARE associated Golgi protein K19302 - 3.6.1.27 0.00000000000000000000000000000005082 140.0
LZS1_k127_850480_47 PFAM Phosphoribosyltransferase K02242 - - 0.00000000000000000000000001175 118.0
LZS1_k127_850480_48 glycosyl transferase family 2 K07011 - - 0.00000000000000000000000001267 122.0
LZS1_k127_850480_49 transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000003283 123.0
LZS1_k127_850480_5 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000054 538.0
LZS1_k127_850480_50 COG0822 NifU homolog involved in Fe-S cluster formation K04488 - - 0.0000000000000000000000001553 109.0
LZS1_k127_850480_51 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000006435 106.0
LZS1_k127_850480_52 binds to the 23S rRNA K02939 - - 0.0000000000000000000000009978 108.0
LZS1_k127_850480_53 Transcriptional regulator, TrmB - - - 0.00000000000000000000003114 108.0
LZS1_k127_850480_54 Amidase K01426 - 3.5.1.4 0.0000000000000000000008851 111.0
LZS1_k127_850480_55 dephospho-CoA kinase activity - - - 0.00000000000000000001366 98.0
LZS1_k127_850480_56 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.0000000000000000007101 92.0
LZS1_k127_850480_57 - K07341 - - 0.000000000000000001527 90.0
LZS1_k127_850480_58 TIGRFAM FeS assembly protein SufD K09015 - - 0.000000000000000001652 96.0
LZS1_k127_850480_59 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000001407 89.0
LZS1_k127_850480_6 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006735 523.0
LZS1_k127_850480_60 Peptidase S24-like - - - 0.0000000000000844 74.0
LZS1_k127_850480_61 PFAM Excinuclease ABC, C subunit, N-terminal K07461 - - 0.0000000000002478 73.0
LZS1_k127_850480_62 phosphorelay signal transduction system - - - 0.00000000002262 70.0
LZS1_k127_850480_64 Baseplate J-like protein - - - 0.000000000115 74.0
LZS1_k127_850480_65 Double zinc ribbon - - - 0.00000000015 68.0
LZS1_k127_850480_66 - - - - 0.00000000027 70.0
LZS1_k127_850480_67 domain protein K07004,K09955,K16915,K20276 - - 0.0000000004974 73.0
LZS1_k127_850480_68 peptidoglycan-binding domain-containing protein - - - 0.00000005428 65.0
LZS1_k127_850480_69 PFAM Membrane protein of K08972 - - 0.0000001937 58.0
LZS1_k127_850480_7 Multidrug transporter MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009595 514.0
LZS1_k127_850480_70 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000003307 54.0
LZS1_k127_850480_71 Domain of unknown function (DUF378) K09779 - - 0.0000003626 54.0
LZS1_k127_850480_72 PFAM major facilitator superfamily MFS_1 - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.0000004185 62.0
LZS1_k127_850480_73 Fibronectin type III domain - - - 0.000000496 63.0
LZS1_k127_850480_74 - - - - 0.0000005461 53.0
LZS1_k127_850480_75 3D domain - - - 0.00001972 57.0
LZS1_k127_850480_76 Ferric reductase like transmembrane component - - - 0.00002869 54.0
LZS1_k127_850480_77 - - - - 0.0000395 46.0
LZS1_k127_850480_78 - - - - 0.00004013 57.0
LZS1_k127_850480_8 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 507.0
LZS1_k127_850480_80 Preprotein translocase SecG subunit K03075 - - 0.0002224 46.0
LZS1_k127_850480_81 HAD-superfamily subfamily IB hydrolase - - - 0.0005532 53.0
LZS1_k127_850480_82 response to antibiotic - - - 0.0007209 48.0
LZS1_k127_850480_83 Helix-turn-helix domain - - - 0.000958 45.0
LZS1_k127_850480_9 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 448.0