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Overview

ID MAG02149
Name LZS1_bin.8
Sample SMP0055
Taxonomy
Kingdom Bacteria
Phylum Patescibacteriota
Class Patescibacteriia
Order 2-12-FULL-60-25
Family 2-12-FULL-60-25
Genus RHKK01
Species
Assembly information
Completeness (%) 70.61
Contamination (%) 2.15
GC content (%) 57.0
N50 (bp) 9,213
Genome size (bp) 961,337

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes707

Gene name Description KEGG GOs EC E-value Score Sequence
LZS1_k127_1177711_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000006653 69.0
LZS1_k127_1177711_1 adenyl ribonucleotide binding - - - 0.00000003783 62.0
LZS1_k127_1177711_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 0.000004184 54.0
LZS1_k127_1177711_3 pathogenesis - - - 0.0002498 53.0
LZS1_k127_1263123_0 Protein of unknown function (DUF4012) - - - 0.00000000000000000000000000000000321 150.0
LZS1_k127_1263123_1 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000005475 138.0
LZS1_k127_1263123_2 Diguanylate cyclase - - - 0.0001582 55.0
LZS1_k127_1388472_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004925 455.0
LZS1_k127_1388472_1 Helicase associated domain (HA2) Add an annotation K03579 - 3.6.4.13 0.0000000005368 70.0
LZS1_k127_1457885_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 342.0
LZS1_k127_1457885_1 PIF1-like helicase K01144 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000005925 220.0
LZS1_k127_1457885_2 PFAM Methionine sulfoxide reductase B K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000001845 179.0
LZS1_k127_1457885_3 Immunoglobulin-like domain of bacterial spore germination - - - 0.0000000000000000000000117 106.0
LZS1_k127_1576504_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 431.0
LZS1_k127_1576504_1 COG0189 Glutathione synthase Ribosomal protein S6 modification K05844 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016874,GO:0016879,GO:0016881,GO:0018169,GO:0018410,GO:0019538,GO:0031668,GO:0033554,GO:0036211,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070739,GO:0071496,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000001135 162.0
LZS1_k127_1576504_2 Protein of unknown function (DUF2817) - - - 0.000000000000001032 83.0
LZS1_k127_1734075_0 dihydroorotase activity K01465 GO:0003674,GO:0003824,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019637,GO:0019856,GO:0034641,GO:0034654,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000004015 207.0
LZS1_k127_1734075_1 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000001594 116.0
LZS1_k127_1734075_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000003361 104.0
LZS1_k127_1734075_3 Belongs to the iron ascorbate-dependent oxidoreductase family K05278 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009058,GO:0009314,GO:0009416,GO:0009628,GO:0009719,GO:0009725,GO:0009733,GO:0009812,GO:0009813,GO:0010033,GO:0016491,GO:0016705,GO:0016706,GO:0042221,GO:0042440,GO:0045431,GO:0046148,GO:0050896,GO:0051213,GO:0051552,GO:0051553,GO:0051554,GO:0051555,GO:0055114,GO:0071704,GO:0080167,GO:1901576,GO:1901615,GO:1901617 1.14.11.23 0.000006902 57.0
LZS1_k127_1734075_6 Dihydroorotate dehydrogenase K17828 - 1.3.1.14 0.0004293 46.0
LZS1_k127_1815838_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.28e-224 713.0
LZS1_k127_1815838_1 Serine dehydrogenase proteinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
LZS1_k127_1815838_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000008994 236.0
LZS1_k127_1815838_3 Protein of unknown function (DUF3048) C-terminal domain - - - 0.0000000000000000000000000000000000000000000004169 181.0
LZS1_k127_1815838_4 Serine hydrolase K07002 - - 0.000000000000000000000000000000000005085 143.0
LZS1_k127_1815838_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000001529 147.0
LZS1_k127_1815838_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000005806 122.0
LZS1_k127_1841659_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 383.0
LZS1_k127_1841659_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 387.0
LZS1_k127_1841659_2 PFAM VanW like protein - - - 0.0000000000000000000000000000000000000000000000000000000001712 226.0
LZS1_k127_1841659_3 belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000001133 143.0
LZS1_k127_1841659_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000001304 79.0
LZS1_k127_1841659_5 Belongs to the peptidase S8 family - - - 0.00004338 53.0
LZS1_k127_1861870_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 344.0
LZS1_k127_1861870_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000005381 175.0
LZS1_k127_1861870_2 DUF218 domain - - - 0.0000000000000000000000000000000001647 139.0
LZS1_k127_1861870_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000147 134.0
LZS1_k127_1861870_4 Transcriptional regulator, TrmB - - - 0.0000000000000277 82.0
LZS1_k127_1870641_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.07e-293 927.0
LZS1_k127_1946695_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 6.243e-194 623.0
LZS1_k127_1946695_1 Ribosomal protein S1 K02945 - - 0.000000000000000000000000000000000000000000000000000000000001253 223.0
LZS1_k127_200718_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 416.0
LZS1_k127_200718_1 tRNA synthetases class I (W and Y) K01867 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 371.0
LZS1_k127_200718_2 COGs COG0503 Adenine guanine phosphoribosyltransferase and related PRPP-binding protein K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000001844 181.0
LZS1_k127_200718_3 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000001268 61.0
LZS1_k127_200718_4 PFAM FecR protein K01387 - 3.4.24.3 0.000008967 59.0
LZS1_k127_20513_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 405.0
LZS1_k127_20513_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003207 274.0
LZS1_k127_2085498_0 Glycosyl transferase family 2 K00721,K10012 - 2.4.1.83,2.4.2.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 342.0
LZS1_k127_2085498_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 310.0
LZS1_k127_2085498_2 Putative zinc binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 298.0
LZS1_k127_2085498_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000001877 173.0
LZS1_k127_2085498_4 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000002097 166.0
LZS1_k127_2085498_5 Hypothetical methyltransferase - - - 0.0000000000000000000000000000000000000001635 160.0
LZS1_k127_2085498_6 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000004617 137.0
LZS1_k127_2085498_7 Cupin - - - 0.0000000000000000000000001919 111.0
LZS1_k127_2085498_8 - - - - 0.00000000000000000000002806 108.0
LZS1_k127_2240217_0 Type II IV secretion system protein K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000815 346.0
LZS1_k127_2240217_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000003622 168.0
LZS1_k127_2240217_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000007364 80.0
LZS1_k127_2240217_3 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000006629 76.0
LZS1_k127_2240217_4 - - - - 0.00000001231 59.0
LZS1_k127_2240217_5 cell adhesion K11904 - - 0.0000001942 64.0
LZS1_k127_2240217_6 Transcriptional regulator K11914 - - 0.0002622 49.0
LZS1_k127_2240217_7 Belongs to the peptidase S8 family - - - 0.0007733 53.0
LZS1_k127_2326253_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001128 269.0
LZS1_k127_2326253_1 Efflux ABC transporter permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009348 263.0
LZS1_k127_2326253_2 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000016 252.0
LZS1_k127_2326253_3 positive regulation of sensory perception of pain - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016020,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0019866,GO:0030061,GO:0031090,GO:0031644,GO:0031646,GO:0031966,GO:0031967,GO:0031975,GO:0032259,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043414,GO:0044057,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0048518,GO:0050789,GO:0051239,GO:0051240,GO:0051930,GO:0051931,GO:0065007,GO:0071704,GO:0140096,GO:1901564,GO:1904058 - 0.000000000000000000001316 102.0
LZS1_k127_2356556_0 Penicillin-binding Protein dimerisation domain K03587,K08384 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 356.0
LZS1_k127_2356556_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000001423 198.0
LZS1_k127_2356556_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000001566 196.0
LZS1_k127_2356556_3 Werner helicase interacting protein 1 K07478 GO:0000731,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006259,GO:0006275,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0030174,GO:0031323,GO:0031326,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048471,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051716,GO:0060255,GO:0065007,GO:0071704,GO:0071897,GO:0080090,GO:0090304,GO:0090329,GO:1901360,GO:1901362,GO:1901576,GO:2000112 - 0.0000000000000000003745 87.0
LZS1_k127_2356556_4 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000003396 74.0
LZS1_k127_2356556_5 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000007595 62.0
LZS1_k127_2412246_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003448 482.0
LZS1_k127_2412246_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000008552 226.0
LZS1_k127_2412246_2 COG0530 Ca2 Na antiporter K07301 - - 0.0000000000001231 81.0
LZS1_k127_2500537_0 Heat shock 70 kDa protein K04043 - - 2.24e-232 736.0
LZS1_k127_2500537_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 333.0
LZS1_k127_2500537_2 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000006457 133.0
LZS1_k127_2500537_3 - - - - 0.00000000000000000000000000002423 124.0
LZS1_k127_2500537_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000008259 104.0
LZS1_k127_2500537_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000014 95.0
LZS1_k127_2520033_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 342.0
LZS1_k127_2520033_1 Glycosyl transferases group 1 - - - 0.000000000000000000000002512 114.0
LZS1_k127_2636350_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1158.0
LZS1_k127_2636350_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 474.0
LZS1_k127_2636350_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000002517 168.0
LZS1_k127_2745467_0 Flavin containing amine oxidoreductase - - - 1.777e-209 679.0
LZS1_k127_2745467_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 519.0
LZS1_k127_2745467_2 Mur ligase family, catalytic domain K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000007685 279.0
LZS1_k127_2745467_3 PFAM Creatininase K01470 - 3.5.2.10 0.0000000000000000000003773 105.0
LZS1_k127_2745467_4 LigT like Phosphoesterase - - - 0.0000000000005952 76.0
LZS1_k127_2745467_5 - - - - 0.000009263 48.0
LZS1_k127_2745467_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001169 54.0
LZS1_k127_2793416_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 428.0
LZS1_k127_2793416_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000001159 259.0
LZS1_k127_2793416_10 - - - - 0.0000006721 63.0
LZS1_k127_2793416_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000006918 187.0
LZS1_k127_2793416_3 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000001366 193.0
LZS1_k127_2793416_4 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000000000000000000138 169.0
LZS1_k127_2793416_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000005344 113.0
LZS1_k127_2793416_6 PFAM pentapeptide repeat protein - - - 0.000000000000000001389 92.0
LZS1_k127_2793416_7 Fibronectin type 3 domain - - - 0.00000000000000003413 97.0
LZS1_k127_2793416_8 Uncharacterized ACR, COG1430 K09005 - - 0.00000000006389 70.0
LZS1_k127_2793416_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000002616 59.0
LZS1_k127_2868761_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 332.0
LZS1_k127_2868761_1 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 323.0
LZS1_k127_2868761_10 - - - - 0.000002427 55.0
LZS1_k127_2868761_11 Vacuolar iron transporter - GO:0000041,GO:0003674,GO:0005215,GO:0005381,GO:0005384,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006810,GO:0006811,GO:0006812,GO:0006826,GO:0006828,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015318,GO:0016020,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030026,GO:0031090,GO:0034220,GO:0034755,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0051716,GO:0055065,GO:0055071,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0097577,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098805 - 0.0002695 50.0
LZS1_k127_2868761_2 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 272.0
LZS1_k127_2868761_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000006738 209.0
LZS1_k127_2868761_4 YceI-like domain - - - 0.0000000000000000000000000000000000000000008221 166.0
LZS1_k127_2868761_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000003621 164.0
LZS1_k127_2868761_6 - - - - 0.000000000000000000000000000004397 131.0
LZS1_k127_2868761_7 thiosulfate sulfurtransferase activity K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000003104 114.0
LZS1_k127_2868761_8 PFAM secretion protein HlyD family protein - - - 0.0000000000000005458 92.0
LZS1_k127_2930834_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 3.384e-224 711.0
LZS1_k127_2930834_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000003342 219.0
LZS1_k127_2967813_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009365 355.0
LZS1_k127_2967813_1 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000001456 104.0
LZS1_k127_2967813_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000002944 97.0
LZS1_k127_2967813_3 Domain of unknown function (DUF4173) - - - 0.000000000000000000006163 108.0
LZS1_k127_2967813_4 - - - - 0.0000000000000000002666 90.0
LZS1_k127_2967813_5 - - - - 0.000000000000000003646 86.0
LZS1_k127_2967813_6 - - - - 0.000000000004851 66.0
LZS1_k127_3111952_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 550.0
LZS1_k127_3111952_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 483.0
LZS1_k127_3111952_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007074 247.0
LZS1_k127_3111952_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000008256 161.0
LZS1_k127_3111952_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000002345 147.0
LZS1_k127_3111952_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000016 64.0
LZS1_k127_3169492_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.616e-218 694.0
LZS1_k127_3169492_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005598 264.0
LZS1_k127_3194481_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003681 257.0
LZS1_k127_3194481_1 glycosyl transferase group 1 K13668 - 2.4.1.346 0.00000000000000000000000000000000000000000003995 176.0
LZS1_k127_3194481_2 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.0000000000000000000000000000000000000000009466 166.0
LZS1_k127_3194481_3 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000001375 143.0
LZS1_k127_3194481_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000006646 125.0
LZS1_k127_3194481_6 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000002285 106.0
LZS1_k127_3194481_7 hydrolase, family 25 - - - 0.0000000000000005119 91.0
LZS1_k127_3194481_9 - - - - 0.0002231 46.0
LZS1_k127_3350178_0 Belongs to the glycosyl hydrolase 43 family K20276 - - 0.00000000000000000000000000006587 136.0
LZS1_k127_3350178_1 Hep Hag repeat protein - - - 0.00000000001017 78.0
LZS1_k127_3350178_2 pilus organization K12132 - 2.7.11.1 0.000000001179 70.0
LZS1_k127_3450802_0 SMART DEAD-like helicase K08282 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 565.0
LZS1_k127_3450802_1 HhH-GPD family K03575 - - 0.000000000000000000000000000000000000000000000000000000003751 212.0
LZS1_k127_3450802_2 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000001402 162.0
LZS1_k127_3450802_3 FAD-binding domain - - - 0.00000000000000000000000000000000002006 144.0
LZS1_k127_3450802_4 Belongs to the Nudix hydrolase family - - - 0.000000001043 67.0
LZS1_k127_3452785_0 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000576 275.0
LZS1_k127_3452785_1 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000354 241.0
LZS1_k127_3452785_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000009535 212.0
LZS1_k127_3452785_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000001025 171.0
LZS1_k127_3452785_4 Glycosyl transferases group 1 K00712,K21011 - 2.4.1.52 0.000003716 58.0
LZS1_k127_3452785_5 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000004923 53.0
LZS1_k127_3465462_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006675 355.0
LZS1_k127_3465462_1 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 342.0
LZS1_k127_3465462_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000002711 66.0
LZS1_k127_3465462_3 valine-tRNA ligase activity K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000003617 58.0
LZS1_k127_355106_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007238 436.0
LZS1_k127_355106_1 Glycosyl transferase 4-like - - - 0.000000000000000000000000005419 123.0
LZS1_k127_3624394_0 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 317.0
LZS1_k127_3624394_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008076 282.0
LZS1_k127_3624394_2 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000008379 141.0
LZS1_k127_3624394_3 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.0000000000000000000000000002249 116.0
LZS1_k127_3624394_4 lytic transglycosylase activity K03194 - - 0.0000000000000000000001201 113.0
LZS1_k127_3624394_5 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000006665 83.0
LZS1_k127_3642614_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 342.0
LZS1_k127_3642614_1 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.00000000000000000000000000000000771 132.0
LZS1_k127_3642614_2 PFAM response regulator receiver - - - 0.00000000000000000002966 99.0
LZS1_k127_3642614_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000001679 63.0
LZS1_k127_3642614_4 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0002896 45.0
LZS1_k127_3642614_5 General secretion pathway protein K02456 - - 0.0008796 48.0
LZS1_k127_3667594_0 Peptidase family M3 K01392 - 3.4.24.15 1.159e-197 635.0
LZS1_k127_3667594_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 399.0
LZS1_k127_3667594_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002125 289.0
LZS1_k127_3667594_3 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000001084 166.0
LZS1_k127_3667594_4 pyridine nucleotide-disulfide oxidoreductase K03885 - 1.6.99.3 0.0000000000000000000000000000000000000007586 165.0
LZS1_k127_3667594_5 Glycosyl transferase - - - 0.00000000000000000000000000000000006428 145.0
LZS1_k127_3667594_6 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000002229 137.0
LZS1_k127_3667594_7 Type III restriction enzyme, res subunit - - - 0.00000000000000000009885 105.0
LZS1_k127_3728823_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004566 288.0
LZS1_k127_3728823_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000059 104.0
LZS1_k127_3728823_2 rRNA binding K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00004901 49.0
LZS1_k127_3791815_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.00000000000000000000000000000000000000000000000001136 202.0
LZS1_k127_3791815_1 protein with SCP PR1 domains - - - 0.0000000000000000005106 98.0
LZS1_k127_3791815_2 Protein of unknown function (DUF1232) - - - 0.00000002064 58.0
LZS1_k127_3791815_3 DoxX - - - 0.00002025 51.0
LZS1_k127_3791815_4 PFAM Vitamin K epoxide reductase - - - 0.00007521 51.0
LZS1_k127_3834171_0 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000001111 125.0
LZS1_k127_3834171_1 NUDIX domain K03574 - 3.6.1.55 0.000000000000000001188 88.0
LZS1_k127_3834171_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000000007719 88.0
LZS1_k127_3834171_3 bis(5'-adenosyl)-triphosphatase activity - - - 0.000000000000001142 80.0
LZS1_k127_3834171_4 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.0002298 52.0
LZS1_k127_3868587_0 PFAM Endonuclease Exonuclease phosphatase K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 316.0
LZS1_k127_3868587_1 Uncharacterized protein conserved in bacteria (DUF2090) - - - 0.00000000000000000000000000000000000000000000000000000000000000008018 228.0
LZS1_k127_3868587_2 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000007275 222.0
LZS1_k127_3868587_3 Drug resistance MFS transporter, drug H antiporter-2 family K18926 - - 0.00000000000000009284 85.0
LZS1_k127_3992635_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006220,GO:0006221,GO:0006231,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009125,GO:0009129,GO:0009130,GO:0009131,GO:0009157,GO:0009159,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009178,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0032259,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042083,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046073,GO:0046078,GO:0046079,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 347.0
LZS1_k127_3992635_1 MafB19-like deaminase - - - 0.0000000000000000000000000000000000000000000000000000000002678 218.0
LZS1_k127_3992635_2 Cytidylyltransferase-like - - - 0.000000000000000000000000000000000000000000000000494 181.0
LZS1_k127_3992635_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000004861 171.0
LZS1_k127_3992635_4 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000009596 166.0
LZS1_k127_3992635_5 HIT domain - - - 0.00000000004007 71.0
LZS1_k127_400093_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003708 265.0
LZS1_k127_400093_1 Glycosyl transferase, family 2 K07011 - - 0.00000000000000000000000000000000000000000000002268 180.0
LZS1_k127_400093_2 nucleotidyltransferase activity K07075 - - 0.00001643 49.0
LZS1_k127_400093_3 Universal bacterial protein YeaZ K14742 - - 0.0002198 49.0
LZS1_k127_4073505_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 341.0
LZS1_k127_4073505_1 and Fe(II)-dependent oxygenase superfamily protein - - - 0.0000000000000000000000000000000000000000000000000000000000001607 226.0
LZS1_k127_4073505_2 50S ribosomal protein L31 K02909 - - 0.0000000000000000002839 91.0
LZS1_k127_4086454_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 417.0
LZS1_k127_4086454_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 385.0
LZS1_k127_4086454_2 BFD domain protein 2Fe-2S -binding domain protein K04488 - - 0.00000000000000000000000000000000000000000000000000000009002 202.0
LZS1_k127_4086454_3 Beta-lactamase - - - 0.00000000000000000000000000005902 127.0
LZS1_k127_4086454_4 Putative RNA methylase family UPF0020 - - - 0.0000000000000000000006273 109.0
LZS1_k127_4086454_5 Transcriptional regulator, BadM Rrf2 family - - - 0.00000000000000000475 93.0
LZS1_k127_4086454_6 4Fe-4S single cluster domain K05337 - - 0.000000000379 63.0
LZS1_k127_4086454_7 COG0694 Thioredoxin-like proteins and domains - - - 0.0002075 48.0
LZS1_k127_411476_0 nucleotide-excision repair K03702,K08999 - - 1.417e-245 777.0
LZS1_k127_411476_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 322.0
LZS1_k127_411476_2 Excalibur calcium-binding domain - - - 0.0009013 48.0
LZS1_k127_4140200_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000007765 224.0
LZS1_k127_4140200_1 Capsule synthesis protein K07282 - - 0.00000000000000000000000000000000000000003559 166.0
LZS1_k127_4140200_10 Papain-like cysteine protease AvrRpt2 - - - 0.0003144 52.0
LZS1_k127_4140200_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000001717 138.0
LZS1_k127_4140200_3 Metallo-beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000000048 132.0
LZS1_k127_4140200_4 30S ribosomal protein S23 - - - 0.00000000000000000000000000001165 123.0
LZS1_k127_4140200_5 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000000000000000001754 98.0
LZS1_k127_4140200_6 PFAM Sporulation and spore germination - - - 0.0000000000003619 81.0
LZS1_k127_4140200_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000002263 57.0
LZS1_k127_4140200_8 PFAM Uncharacterised protein family UPF0150 - - - 0.0000001106 56.0
LZS1_k127_4140200_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00002388 49.0
LZS1_k127_4158015_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 546.0
LZS1_k127_4158015_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000006591 198.0
LZS1_k127_4158015_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000008018 185.0
LZS1_k127_4158015_3 Acid phosphatase homologues - - - 0.0000000000000000000006731 102.0
LZS1_k127_4158015_4 Phage integrase family - - - 0.0000000003059 65.0
LZS1_k127_4215952_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 289.0
LZS1_k127_4215952_2 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.00000000000000000000000008166 123.0
LZS1_k127_4215952_3 ATPase or kinase K06925 - - 0.0000000000000000001779 94.0
LZS1_k127_4215952_4 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000005372 82.0
LZS1_k127_4215952_5 glycosyl transferase group 1 - - - 0.000005798 51.0
LZS1_k127_4443978_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 451.0
LZS1_k127_4443978_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 355.0
LZS1_k127_4443978_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.0000000000000000000000000000000000000000000000003118 184.0
LZS1_k127_4443978_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000004 97.0
LZS1_k127_445118_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.956e-308 989.0
LZS1_k127_445118_1 TIGRFAM UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001656 272.0
LZS1_k127_445118_2 GMP synthase (glutamine-hydrolyzing) activity K01951 - 6.3.5.2 0.00000000000000000000000000000000005768 143.0
LZS1_k127_445118_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000003238 128.0
LZS1_k127_445118_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000004163 103.0
LZS1_k127_445118_5 PFAM extracellular solute-binding protein family 1 K02027 - - 0.000000000000000000005864 107.0
LZS1_k127_445118_6 Biotin carboxylase - - - 0.0000000000000002247 92.0
LZS1_k127_4522781_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 515.0
LZS1_k127_4522781_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 416.0
LZS1_k127_4522781_10 peptidase C60 sortase A and B - - - 0.00000000000000000000002805 110.0
LZS1_k127_4522781_11 TM2 domain - - - 0.0000000000000113 80.0
LZS1_k127_4522781_12 Endonuclease containing a URI domain K07461 - - 0.00000000000001212 84.0
LZS1_k127_4522781_13 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000001028 68.0
LZS1_k127_4522781_14 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000001955 71.0
LZS1_k127_4522781_15 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000002917 69.0
LZS1_k127_4522781_16 nuclease activity K06218 - - 0.000000001394 62.0
LZS1_k127_4522781_17 Phosphoglycerate mutase family K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0002412 49.0
LZS1_k127_4522781_2 Transketolase, pyrimidine binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 366.0
LZS1_k127_4522781_3 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 292.0
LZS1_k127_4522781_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000002943 229.0
LZS1_k127_4522781_5 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000000000000000001005 209.0
LZS1_k127_4522781_6 iron ion binding - - - 0.0000000000000000000000000000000000000000009157 167.0
LZS1_k127_4522781_7 Ribose 5-phosphate isomerase K01808,K01819 - 5.3.1.26,5.3.1.6 0.00000000000000000000000000004237 121.0
LZS1_k127_4522781_8 TIGRFAM Ribulose-phosphate 3-epimerase K01783 - 5.1.3.1 0.00000000000000000000000003917 116.0
LZS1_k127_4522781_9 Domain of unknown function (DUF4349) - - - 0.0000000000000000000000004562 117.0
LZS1_k127_4613640_0 BRO family, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 364.0
LZS1_k127_4613640_1 pfam abc K06158,K19350 - - 0.0000000000000000000000000000000000000000000000000000000000781 225.0
LZS1_k127_4704327_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 365.0
LZS1_k127_4704327_1 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 350.0
LZS1_k127_4704327_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000005974 185.0
LZS1_k127_4704327_3 DEAD DEAH box helicase domain protein K06877 - - 0.00000000000000000000000000000001255 132.0
LZS1_k127_479815_0 AAA-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 374.0
LZS1_k127_479815_1 Protein of unknown function (DUF1428) - - - 0.00000000000000000000000000000000000317 141.0
LZS1_k127_479815_2 PFAM Transglycosylase associated protein - - - 0.0000000000000000000000001088 108.0
LZS1_k127_479815_3 GIY-YIG catalytic domain K07461 - - 0.000000000000000001629 89.0
LZS1_k127_479815_4 PFAM Phosphoribosyltransferase K02242 - - 0.00000000000000001923 90.0
LZS1_k127_479815_6 - - - - 0.00000000002077 66.0
LZS1_k127_479815_7 - - - - 0.00000000006444 65.0
LZS1_k127_479815_8 - - - - 0.00002454 50.0
LZS1_k127_4848349_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 413.0
LZS1_k127_4848349_1 CYTH domain - - - 0.0000000000000000000000003394 111.0
LZS1_k127_4848349_2 Protein of unknown function (DUF541) K09807 - - 0.000000000006789 70.0
LZS1_k127_4872469_0 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000006314 217.0
LZS1_k127_4872469_1 transporter (mgtE) K06213 - - 0.0000000000000000000000000000000000000000000000000000006976 205.0
LZS1_k127_4872469_2 COG1651 Protein-disulfide isomerase - - - 0.000000000000000000000000000000000000000006997 163.0
LZS1_k127_4872469_3 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000001165 139.0
LZS1_k127_4872469_4 COG1651 Protein-disulfide isomerase K21990 - - 0.0000000000000000000000000000008095 129.0
LZS1_k127_4872469_5 Protein of unknown function (DUF1761) - - - 0.000000000000000004235 89.0
LZS1_k127_4872469_6 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.00000000000000009077 83.0
LZS1_k127_4872469_7 Protein of unknown function (DUF1653) - - - 0.000000001124 63.0
LZS1_k127_4876300_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017076,GO:0017111,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034335,GO:0034641,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 5.99.1.3 1.139e-275 871.0
LZS1_k127_4876300_1 ABC transporter, transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001601 285.0
LZS1_k127_4876300_2 Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000001757 177.0
LZS1_k127_4876300_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000724,GO:0000725,GO:0003674,GO:0003678,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009378,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0031668,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140097,GO:1901360 3.6.4.12 0.000000000000000000000000000000000002981 145.0
LZS1_k127_4876300_4 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000006408 145.0
LZS1_k127_4876300_5 Beta-lactamase superfamily domain - - - 0.0000000000000000000000001856 113.0
LZS1_k127_4876300_6 PFAM Dual specificity protein phosphatase - - - 0.00000000000000001087 89.0
LZS1_k127_4876300_7 DoxX family K15977 - - 0.000000000001993 73.0
LZS1_k127_4957537_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 351.0
LZS1_k127_4957537_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000009427 104.0
LZS1_k127_5018712_0 PFAM ABC transporter related K06158 - - 0.0000000000000000000000000000009902 132.0
LZS1_k127_5027179_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.891e-287 900.0
LZS1_k127_5027179_1 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 519.0
LZS1_k127_5027179_2 TraM recognition site of TraD and TraG - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 312.0
LZS1_k127_5027179_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005766 291.0
LZS1_k127_5027179_4 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000004951 227.0
LZS1_k127_5027179_5 DoxX K16937 - 1.8.5.2 0.0000000000000000000000000005699 118.0
LZS1_k127_5027179_6 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000000000000009593 76.0
LZS1_k127_5027179_7 signal transduction protein containing a membrane domain, an EAL and a GGDEF domain - - - 0.0000000000002783 81.0
LZS1_k127_5027179_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000001169 79.0
LZS1_k127_5027179_9 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000189 71.0
LZS1_k127_5040220_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.001e-304 948.0
LZS1_k127_5040220_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000001735 200.0
LZS1_k127_5040220_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000632 168.0
LZS1_k127_5040220_3 PFAM peptidase - - - 0.0001697 46.0
LZS1_k127_5040220_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0005817 44.0
LZS1_k127_5052922_0 Membrane K04088,K14393 - - 4.423e-225 725.0
LZS1_k127_5052922_1 Anticodon-binding domain of tRNA K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 455.0
LZS1_k127_5052922_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000003063 215.0
LZS1_k127_5052922_3 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000307 184.0
LZS1_k127_5052922_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000005034 71.0
LZS1_k127_5052922_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000003369 68.0
LZS1_k127_5061193_0 ATPase family associated with various cellular activities (AAA) K03696 - - 0.000000000000000000000000000000000000000002984 175.0
LZS1_k127_508429_0 Cell division protein FtsA K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 386.0
LZS1_k127_508429_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000002444 243.0
LZS1_k127_508429_2 Protein of unknown function (DUF4012) - - - 0.000000000000000000000000000000000000001107 167.0
LZS1_k127_5141980_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002661 271.0
LZS1_k127_5141980_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000007074 214.0
LZS1_k127_5141980_2 Thioredoxin - - - 0.000000000000000000000000000000000001021 148.0
LZS1_k127_5141980_3 Preprotein translocase SecG subunit K03075 - - 0.000000008468 60.0
LZS1_k127_5285602_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 3.351e-255 806.0
LZS1_k127_5285602_1 ABC transporter, ATP-binding protein K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 493.0
LZS1_k127_5285602_2 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 357.0
LZS1_k127_5285602_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 310.0
LZS1_k127_5285602_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000001149 235.0
LZS1_k127_5285602_5 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000007994 193.0
LZS1_k127_5285602_6 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000002144 172.0
LZS1_k127_5285602_7 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.00000000000000000000000000000000000000001767 164.0
LZS1_k127_5285602_8 Cytidylate kinase - - - 0.00000000000000000000000003261 115.0
LZS1_k127_5285602_9 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000331 94.0
LZS1_k127_5413336_0 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001668 288.0
LZS1_k127_5413336_1 Cytidylyltransferase - - - 0.000000000000000000000000000000000000000000000000498 192.0
LZS1_k127_5413336_10 Oxidoreductase FAD-binding domain K02613 - - 0.000000000448 69.0
LZS1_k127_5413336_11 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000003511 60.0
LZS1_k127_5413336_12 Bacterial membrane protein YfhO - - - 0.0003883 54.0
LZS1_k127_5413336_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000339 140.0
LZS1_k127_5413336_3 TIGRFAM methyltransferase FkbM family - - - 0.0000000000000000000000000000004804 134.0
LZS1_k127_5413336_4 capsule polysaccharide K07265 - - 0.00000000000000000000000000003954 133.0
LZS1_k127_5413336_5 PFAM Polysaccharide biosynthesis protein K03328 - - 0.00000000000000000000000000004289 134.0
LZS1_k127_5413336_7 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000002267 115.0
LZS1_k127_5413336_8 Methyltransferase domain - - - 0.00000000000000000004338 105.0
LZS1_k127_5413336_9 Psort location CytoplasmicMembrane, score - - - 0.0000000000001721 85.0
LZS1_k127_5436455_0 glutamate-tRNA ligase activity K01885,K09698 - 6.1.1.17,6.1.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 370.0
LZS1_k127_5436455_1 Glycosyl transferase, WecB TagA CpsF family K05946 - 2.4.1.187 0.00000000000000000000000000000000000002993 151.0
LZS1_k127_5436508_0 domain, Protein K09766 - - 0.0000000002382 73.0
LZS1_k127_5527737_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 0.00000000000000000000000000000000000000000000000000000003603 201.0
LZS1_k127_5527737_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000003859 139.0
LZS1_k127_5527737_2 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000009957 137.0
LZS1_k127_554246_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 509.0
LZS1_k127_554246_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 295.0
LZS1_k127_554246_2 Thrombospondin type 3 repeat - - - 0.000000000000000000000000001305 125.0
LZS1_k127_5550942_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000001413 236.0
LZS1_k127_5550942_1 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000003331 185.0
LZS1_k127_5550942_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 0.00000000000000000000000000000000000001183 149.0
LZS1_k127_5579646_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 305.0
LZS1_k127_5579646_1 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000001746 127.0
LZS1_k127_5579646_2 bile acid:sodium symporter activity K03453 - - 0.00000000000000006767 92.0
LZS1_k127_5579646_3 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000001104 68.0
LZS1_k127_5579646_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000004076 57.0
LZS1_k127_5600142_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 365.0
LZS1_k127_5600142_1 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005756 293.0
LZS1_k127_5600142_2 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002266 282.0
LZS1_k127_5600142_3 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000005043 254.0
LZS1_k127_5600142_4 - - - - 0.0000000000000000000000000000000000000000000000000000000004248 208.0
LZS1_k127_5600142_5 - - - - 0.00000000000005006 80.0
LZS1_k127_5600142_6 Methyltransferase domain protein - - - 0.000000142 61.0
LZS1_k127_5612710_0 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001508 288.0
LZS1_k127_5612710_1 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000611 106.0
LZS1_k127_5750537_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.508e-216 694.0
LZS1_k127_5750537_1 PFAM magnesium chelatase ChlI subunit K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 513.0
LZS1_k127_5750537_10 CYTH K05873 - 4.6.1.1 0.0000001527 60.0
LZS1_k127_5750537_11 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000918 54.0
LZS1_k127_5750537_12 PFAM Tetratricopeptide repeat - - - 0.00001018 59.0
LZS1_k127_5750537_13 - - - - 0.0006667 44.0
LZS1_k127_5750537_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003387 232.0
LZS1_k127_5750537_3 STAS-like domain of unknown function (DUF4325) - - - 0.000000000000000000000000000000000000000000000000000000253 207.0
LZS1_k127_5750537_4 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000001347 192.0
LZS1_k127_5750537_5 NYN domain - - - 0.000000000000000000000000000000000000000000000003933 179.0
LZS1_k127_5750537_6 LVIVD repeat - - - 0.000000000000000001339 104.0
LZS1_k127_5750537_7 COG1734 DnaK suppressor protein - - - 0.0000000000004377 74.0
LZS1_k127_5750537_8 tail collar domain protein - - - 0.00000000001415 81.0
LZS1_k127_5750537_9 Hep Hag repeat protein - - - 0.0000000003796 76.0
LZS1_k127_5798923_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009024 288.0
LZS1_k127_5798923_1 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000002987 237.0
LZS1_k127_5798923_2 PFAM metal-dependent phosphohydrolase, HD sub domain K07023 - - 0.0000000000000000000000000000000001629 136.0
LZS1_k127_5798923_3 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000000000000000000004157 134.0
LZS1_k127_5798923_4 NUDIX domain - - - 0.00000000000000000000000000000001414 132.0
LZS1_k127_5798923_5 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.00000004477 57.0
LZS1_k127_5865146_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 477.0
LZS1_k127_5865146_1 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005396 271.0
LZS1_k127_5865146_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000003695 217.0
LZS1_k127_5865146_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000002463 157.0
LZS1_k127_5865146_4 cellulose binding - - - 0.000000000000000000000006756 114.0
LZS1_k127_5865146_5 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000008546 106.0
LZS1_k127_5982154_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 447.0
LZS1_k127_5982154_1 methyltransferase - - - 0.000000000000000000009043 104.0
LZS1_k127_5982154_2 PFAM Methyltransferase type 11 - - - 0.00000000000000004304 88.0
LZS1_k127_5982154_3 Methyltransferase domain - - - 0.0000000000001148 81.0
LZS1_k127_6071498_0 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 306.0
LZS1_k127_6071498_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008444,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0016740,GO:0016772,GO:0016780,GO:0017169,GO:0019637,GO:0030312,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0071944,GO:0090407,GO:1901576 2.7.8.41,2.7.8.5 0.0000000000000005548 85.0
LZS1_k127_6071498_2 cell cycle K05589,K13052 - - 0.0000003499 57.0
LZS1_k127_6120484_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 9.7e-300 942.0
LZS1_k127_6120484_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008728,GO:0008893,GO:0009116,GO:0009117,GO:0009119,GO:0009150,GO:0009259,GO:0009605,GO:0009987,GO:0009991,GO:0015969,GO:0016020,GO:0016740,GO:0016772,GO:0016778,GO:0016787,GO:0016788,GO:0016794,GO:0019637,GO:0019693,GO:0030312,GO:0031667,GO:0033865,GO:0033875,GO:0034032,GO:0034035,GO:0034641,GO:0042278,GO:0042578,GO:0042594,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046128,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:1901068,GO:1901135,GO:1901360,GO:1901564,GO:1901657 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 492.0
LZS1_k127_6120484_2 PFAM TrkA-N domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 469.0
LZS1_k127_6120484_3 sporulation initiation inhibitor protein Soj K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 291.0
LZS1_k127_6120484_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000007524 223.0
LZS1_k127_6120484_5 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000739 218.0
LZS1_k127_6120484_6 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0016787,GO:0016788,GO:0040007,GO:0044464,GO:0052689,GO:0071944,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000002233 177.0
LZS1_k127_6120484_7 Bacteriophage replication gene A protein (GPA) - - - 0.00000009516 54.0
LZS1_k127_6337546_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 492.0
LZS1_k127_6337546_1 GIY-YIG catalytic domain K07461 - - 0.000000000000000000000002587 106.0
LZS1_k127_6337546_2 UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain - - - 0.0000000000000001894 81.0
LZS1_k127_6337546_3 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000003842 61.0
LZS1_k127_6337546_4 Domain of unknown function (DUF378) - - - 0.000009652 51.0
LZS1_k127_6435562_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5e-324 1015.0
LZS1_k127_6435562_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000006274 245.0
LZS1_k127_6435562_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.000000001019 67.0
LZS1_k127_6437397_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009424 461.0
LZS1_k127_6437397_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000001219 233.0
LZS1_k127_6437397_2 Protein phosphatase 2C K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16 0.00000000002329 74.0
LZS1_k127_6437397_3 Transmembrane amino acid transporter protein - - - 0.0003859 52.0
LZS1_k127_654883_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 453.0
LZS1_k127_654883_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 349.0
LZS1_k127_654883_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000001955 189.0
LZS1_k127_654883_3 methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.0000000000000000002 95.0
LZS1_k127_654883_4 Cro/C1-type HTH DNA-binding domain - - - 0.00000007591 57.0
LZS1_k127_671060_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 6.248e-301 947.0
LZS1_k127_671060_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000001387 125.0
LZS1_k127_671060_2 belongs to the carbohydrate kinase PfkB family - - - 0.000000000003426 78.0
LZS1_k127_6791336_0 Type II restriction enzyme, methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004827 233.0
LZS1_k127_6791336_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000001727 202.0
LZS1_k127_6791336_2 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000002451 178.0
LZS1_k127_6791336_3 Glycosyl transferase 4-like domain - - - 0.000000000000005807 86.0
LZS1_k127_6791336_4 Uncharacterized conserved protein (DUF2304) K09153 - - 0.000001075 57.0
LZS1_k127_6896932_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 415.0
LZS1_k127_6896932_1 ATPases associated with a variety of cellular activities K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003481 259.0
LZS1_k127_6896932_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000001135 106.0
LZS1_k127_6896932_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000005104 102.0
LZS1_k127_6896932_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000005566 83.0
LZS1_k127_6896932_5 NYN domain - - - 0.0000002708 61.0
LZS1_k127_6896932_6 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00005216 52.0
LZS1_k127_6896932_7 - - - - 0.0000598 46.0
LZS1_k127_6933913_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002138 568.0
LZS1_k127_6933913_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000002021 226.0
LZS1_k127_6933913_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000003315 98.0
LZS1_k127_6937609_0 PFAM tRNA synthetase class II (G H P and S) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 374.0
LZS1_k127_6937609_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000003827 252.0
LZS1_k127_6937609_10 TIGRFAM cysteine-rich repeat protein - - - 0.000000000000000000002449 113.0
LZS1_k127_6937609_11 endonuclease activity - - - 0.00000000006988 67.0
LZS1_k127_6937609_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.000000000205 67.0
LZS1_k127_6937609_13 RelB antitoxin - - - 0.00000008932 59.0
LZS1_k127_6937609_14 domain, Protein - - - 0.00000424 63.0
LZS1_k127_6937609_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000156 249.0
LZS1_k127_6937609_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000004381 246.0
LZS1_k127_6937609_4 EVE domain - - - 0.0000000000000000000000000000000000000002686 153.0
LZS1_k127_6937609_5 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966 - 2.7.7.13 0.0000000000000000000000000000000004237 139.0
LZS1_k127_6937609_6 nuclear chromosome segregation - - - 0.00000000000000000000000000000002534 134.0
LZS1_k127_6937609_7 Yqey-like protein K09117 - - 0.0000000000000000000000000000003682 128.0
LZS1_k127_6937609_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000003311 131.0
LZS1_k127_6937609_9 Domain of unknown function (DUF4215) - - - 0.0000000000000000000000000001759 137.0
LZS1_k127_6939620_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 306.0
LZS1_k127_6939620_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000004721 199.0
LZS1_k127_6939620_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000131 115.0
LZS1_k127_6968124_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 567.0
LZS1_k127_6976791_0 DEAD DEAH box helicase K03654 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 524.0
LZS1_k127_6976791_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009634 383.0
LZS1_k127_6976791_10 LVIVD repeat - - - 0.00000000006037 75.0
LZS1_k127_6976791_11 endonuclease activity K06877,K07451 - - 0.000001061 57.0
LZS1_k127_6976791_2 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003037 277.0
LZS1_k127_6976791_3 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007911 265.0
LZS1_k127_6976791_4 PFAM sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001527 251.0
LZS1_k127_6976791_5 PFAM Bacterial type II secretion system protein F domain K02653 - - 0.000000000000000000000000000000000000000000000000000001977 205.0
LZS1_k127_6976791_6 tyrosine recombinase XerC K03733,K04763 - - 0.0000000000000000000000000000000000000000000002361 179.0
LZS1_k127_6976791_7 uridine kinase K00876,K09702 - 2.7.1.48 0.00000000000000000000000000000000000000006005 158.0
LZS1_k127_6976791_8 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.0000000000000000000000006492 109.0
LZS1_k127_6976791_9 Uncharacterized conserved protein (DUF2196) - - - 0.000000000000000008443 84.0
LZS1_k127_7001493_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 432.0
LZS1_k127_7001493_1 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 449.0
LZS1_k127_7001493_10 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000004651 63.0
LZS1_k127_7001493_11 Ribonuclease P K03536 - 3.1.26.5 0.000000005089 63.0
LZS1_k127_7001493_12 response regulator K07713 - - 0.000000008228 59.0
LZS1_k127_7001493_13 3D domain protein - - - 0.00002211 54.0
LZS1_k127_7001493_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 410.0
LZS1_k127_7001493_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 400.0
LZS1_k127_7001493_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000006135 234.0
LZS1_k127_7001493_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000001279 224.0
LZS1_k127_7001493_6 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.00000000000000000000000000000000000000000000004148 185.0
LZS1_k127_7001493_7 Protein conserved in bacteria - - - 0.00000000000000000000000009526 110.0
LZS1_k127_7001493_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000001515 95.0
LZS1_k127_7001493_9 DUF167 K09131 - - 0.0000000000000002151 82.0
LZS1_k127_7032803_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 374.0
LZS1_k127_7032803_1 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000188 165.0
LZS1_k127_7032803_2 PFAM Excinuclease ABC, C subunit domain protein K07461 - - 0.00000000000000000000000000008355 119.0
LZS1_k127_7032803_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000009356 60.0
LZS1_k127_7032803_5 S23 ribosomal protein - - - 0.0000003456 54.0
LZS1_k127_7032803_6 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00003493 50.0
LZS1_k127_7032803_7 protein secretion by the type IV secretion system K03201 - - 0.0001755 55.0
LZS1_k127_7085261_0 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005756 386.0
LZS1_k127_7108271_0 lysyl-tRNA synthetase K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000003569 242.0
LZS1_k127_7108271_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000002276 142.0
LZS1_k127_7108271_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000001449 83.0
LZS1_k127_7108271_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000006696 78.0
LZS1_k127_7108271_4 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000004797 76.0
LZS1_k127_7108611_0 tRNA synthetases class II (D, K and N) K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005888 532.0
LZS1_k127_7108611_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 484.0
LZS1_k127_7108611_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000002492 121.0
LZS1_k127_7108611_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000009512 111.0
LZS1_k127_7108611_4 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000005032 111.0
LZS1_k127_7150598_0 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 293.0
LZS1_k127_7150598_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002432 274.0
LZS1_k127_7150598_10 23S rRNA-intervening sequence protein - - - 0.000000009583 61.0
LZS1_k127_7150598_11 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000003356 57.0
LZS1_k127_7150598_12 Stage II sporulation protein K06381 - - 0.00002218 58.0
LZS1_k127_7150598_13 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0001589 49.0
LZS1_k127_7150598_14 with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000928 50.0
LZS1_k127_7150598_15 - - - - 0.0009325 46.0
LZS1_k127_7150598_2 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000001217 154.0
LZS1_k127_7150598_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000971 129.0
LZS1_k127_7150598_5 stage II sporulation protein K06381 - - 0.000000000000000004085 100.0
LZS1_k127_7150598_6 Zincin-like metallopeptidase - - - 0.00000000000000003682 86.0
LZS1_k127_7150598_7 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000002557 84.0
LZS1_k127_7150598_8 glucosamine-1-phosphate N-acetyltransferase activity - - - 0.000000000000000389 89.0
LZS1_k127_7150598_9 Belongs to the UPF0109 family K06960 - - 0.0000000000008189 74.0
LZS1_k127_7158146_0 Belongs to the ClpA ClpB family K03696 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 599.0
LZS1_k127_7158146_1 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 GO:0003674,GO:0003824,GO:0004615,GO:0016853,GO:0016866,GO:0016868 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000004582 262.0
LZS1_k127_7158146_2 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009719 258.0
LZS1_k127_7158146_3 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000294 224.0
LZS1_k127_7158146_4 Na+/H+ antiporter 1 - - - 0.0000000000000000000005552 106.0
LZS1_k127_720991_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 594.0
LZS1_k127_720991_1 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000004228 224.0
LZS1_k127_720991_2 MazG-like family - - - 0.00000000000002026 78.0
LZS1_k127_720991_3 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.000000000001977 67.0
LZS1_k127_720991_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0002790,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032940,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00001934 53.0
LZS1_k127_720991_5 - - - - 0.0006993 48.0
LZS1_k127_7234262_0 helicase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 460.0
LZS1_k127_7234262_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008522 321.0
LZS1_k127_7234262_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000002466 257.0
LZS1_k127_7234262_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000003424 203.0
LZS1_k127_7234262_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000104 203.0
LZS1_k127_7234262_5 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.0000000000000000000000000000000003266 141.0
LZS1_k127_7234262_6 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000001696 117.0
LZS1_k127_7234262_7 N-acetylmuramoyl-L-alanine amidase K01447 - 3.5.1.28 0.00002772 56.0
LZS1_k127_730693_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 518.0
LZS1_k127_730693_1 Belongs to the SEDS family K03588 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006022 271.0
LZS1_k127_730693_2 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000004548 238.0
LZS1_k127_730693_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000001043 246.0
LZS1_k127_730693_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K01924,K02563 - 2.4.1.227,6.3.2.8 0.000000000000000000000000000000000000000000000000042 192.0
LZS1_k127_730693_5 Ribosomal L27 protein K02899 - - 0.000000000000000000000001375 106.0
LZS1_k127_730693_6 23S rRNA-intervening sequence protein - - - 0.000000000000000000000002184 107.0
LZS1_k127_730693_7 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000018 106.0
LZS1_k127_730693_8 NifU-like domain - - - 0.0000000000000001508 81.0
LZS1_k127_7319476_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 389.0
LZS1_k127_7319476_1 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 GO:0003674,GO:0003824,GO:0004844,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0097510,GO:0140097,GO:1901360 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 326.0
LZS1_k127_7319476_2 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003896 257.0
LZS1_k127_7319476_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000009304 230.0
LZS1_k127_7319476_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000008021 164.0
LZS1_k127_7319476_5 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000006924 148.0
LZS1_k127_7319476_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000005719 114.0
LZS1_k127_7319476_7 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000000000009459 89.0
LZS1_k127_7319476_8 NlpE N-terminal domain - - - 0.000000000000003706 81.0
LZS1_k127_738650_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 1.362e-293 944.0
LZS1_k127_738650_1 PFAM Protein synthesis factor, GTP-binding K06207 - - 6.51e-213 683.0
LZS1_k127_738650_10 ORF6N domain - - - 0.00001443 53.0
LZS1_k127_738650_2 PFAM RNA-metabolising metallo-beta-lactamase K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 376.0
LZS1_k127_738650_3 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000000000003436 209.0
LZS1_k127_738650_4 COG1078 HD superfamily phosphohydrolases K06885 - - 0.00000000000000000000000000000000000000000000000000000004332 215.0
LZS1_k127_738650_5 self proteolysis - - - 0.000000000000000000000000000000009636 144.0
LZS1_k127_738650_7 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000007105 123.0
LZS1_k127_738650_8 Sh3 type 3 domain protein K04772,K08372,K22278 - 3.5.1.104 0.000000000129 73.0
LZS1_k127_738650_9 - - - - 0.00000001782 63.0
LZS1_k127_7412436_0 Virulence protein RhuM family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 329.0
LZS1_k127_7412436_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008558 269.0
LZS1_k127_7412436_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002563 258.0
LZS1_k127_7412436_3 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000627 153.0
LZS1_k127_7412436_4 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000002112 119.0
LZS1_k127_7412436_5 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.000215 44.0
LZS1_k127_7414442_0 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000003472 143.0
LZS1_k127_7414442_1 Belongs to the peptidase S11 family K01286,K07258 GO:0003674,GO:0003824,GO:0004175,GO:0004180,GO:0004185,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0009002,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0043170,GO:0044238,GO:0044464,GO:0070008,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.16.4 0.00004519 48.0
LZS1_k127_7528347_0 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000002896 147.0
LZS1_k127_7528347_1 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000001255 131.0
LZS1_k127_7528347_2 AI-2E family transporter - - - 0.0000000000000000000000000001652 128.0
LZS1_k127_7528347_3 protein-(glutamine-N5) methyltransferase activity - - - 0.000000000000000000000005373 108.0
LZS1_k127_7528347_4 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000003783 101.0
LZS1_k127_7528347_5 Ribosomal protein L35 K02916 - - 0.0001219 48.0
LZS1_k127_7566495_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 398.0
LZS1_k127_7566495_1 COGs COG2114 Adenylate cyclase family 3 (some protein contain HAMP domain) - - - 0.0000000000000000000000000000000000000000000000007128 185.0
LZS1_k127_7566495_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000000003544 123.0
LZS1_k127_7566495_3 RNA recognition motif - - - 0.00000000000000000000006098 102.0
LZS1_k127_7566495_4 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000003937 60.0
LZS1_k127_7566495_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.00000536 57.0
LZS1_k127_7595675_0 DegT/DnrJ/EryC1/StrS aminotransferase family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 392.0
LZS1_k127_7595675_1 PFAM N-acetylneuraminic acid synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 337.0
LZS1_k127_7595675_2 Polysaccharide biosynthesis protein CapD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 302.0
LZS1_k127_7595675_3 PFAM UDP-N-acetylglucosamine 2-epimerase K18429 - 3.2.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000000001263 273.0
LZS1_k127_7595675_4 O-acyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000101 211.0
LZS1_k127_7595675_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000004911 203.0
LZS1_k127_7595675_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000007546 161.0
LZS1_k127_7595675_7 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.000000000000000000000000000004578 128.0
LZS1_k127_7595675_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000005796 89.0
LZS1_k127_7595675_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000003929 59.0
LZS1_k127_7622181_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.253e-195 619.0
LZS1_k127_7622181_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 550.0
LZS1_k127_7622181_10 Probable zinc-ribbon domain - - - 0.000000002647 64.0
LZS1_k127_7622181_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000008922 53.0
LZS1_k127_7622181_2 COG1131 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000001371 231.0
LZS1_k127_7622181_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000004093 161.0
LZS1_k127_7622181_4 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.0000000000000000000000000000000000000001541 156.0
LZS1_k127_7622181_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000007894 156.0
LZS1_k127_7622181_6 Transport permease protein K01992 - - 0.000000000000000000000000000000000003924 147.0
LZS1_k127_7622181_7 Psort location Cytoplasmic, score K07043 - - 0.0000000000000000000000000000000000244 141.0
LZS1_k127_7622181_8 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000001983 119.0
LZS1_k127_7622181_9 Nucleotide binding protein, PINc - - - 0.0000000000000000009852 92.0
LZS1_k127_7774184_0 Belongs to the DEAD box helicase family K05592,K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 496.0
LZS1_k127_7774184_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 364.0
LZS1_k127_7774184_10 Methyltransferase domain - - - 0.0000000000004962 72.0
LZS1_k127_7774184_11 DSBA-like thioredoxin domain - - - 0.000000000001511 75.0
LZS1_k127_7774184_12 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00002691 50.0
LZS1_k127_7774184_2 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000001157 231.0
LZS1_k127_7774184_3 permease - - - 0.00000000000000000000000000000000000000000006079 173.0
LZS1_k127_7774184_4 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000002015 132.0
LZS1_k127_7774184_5 PFAM nuclease (SNase domain protein) K01174 - 3.1.31.1 0.0000000000000000000000000000008998 129.0
LZS1_k127_7774184_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000001844 111.0
LZS1_k127_7774184_7 Glutaredoxin - - - 0.00000000000000000000003707 100.0
LZS1_k127_7774184_8 HAD-superfamily subfamily IB hydrolase - - - 0.00000000000001918 83.0
LZS1_k127_7774184_9 Protein of unknown function (DUF3298) - - - 0.00000000000008958 82.0
LZS1_k127_7781104_0 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000001409 179.0
LZS1_k127_7781104_1 nucleotidyltransferase activity - - - 0.000003124 58.0
LZS1_k127_7781104_2 PRC-barrel domain - - - 0.0004972 46.0
LZS1_k127_7832627_0 Large extracellular alpha-helical protein K06894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 524.0
LZS1_k127_7832627_1 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001098 267.0
LZS1_k127_7832627_10 regulator of chromosome condensation, RCC1 - - - 0.00000002807 57.0
LZS1_k127_7832627_2 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000005411 186.0
LZS1_k127_7832627_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000001102 183.0
LZS1_k127_7832627_4 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000003278 158.0
LZS1_k127_7832627_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000818 122.0
LZS1_k127_7832627_6 Memo-like protein K06990 - - 0.00000000000000000724 94.0
LZS1_k127_7832627_7 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.00000000000000002122 86.0
LZS1_k127_7832627_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000001898 84.0
LZS1_k127_7832627_9 PFAM AhpC TSA family - - - 0.00000001245 63.0
LZS1_k127_7872231_0 Fic family - - - 0.0000000000000000000000000000000000000000000000000005687 194.0
LZS1_k127_7872231_1 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.000000000000000000000000000000000000000001275 162.0
LZS1_k127_7872231_2 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0008481 45.0
LZS1_k127_7905240_0 PFAM Peptidase M23 K21471 - - 0.000000000000000000000000001462 126.0
LZS1_k127_7916801_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016300,GO:0016740,GO:0016741,GO:0030488,GO:0030696,GO:0030697,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007178 283.0
LZS1_k127_7916801_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000004335 193.0
LZS1_k127_7916801_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000001202 168.0
LZS1_k127_7916801_3 COG0463 Glycosyltransferases involved in cell wall biogenesis K00786 - - 0.00000000000000000000000000000227 132.0
LZS1_k127_7916801_4 SpoU rRNA Methylase family - - - 0.00000000000000000000000000001839 122.0
LZS1_k127_7916801_5 nitrite reductase [NAD(P)H] activity K15762 - - 0.00000004734 59.0
LZS1_k127_7923590_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 332.0
LZS1_k127_7923590_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000002275 207.0
LZS1_k127_7923590_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000001588 188.0
LZS1_k127_7923590_3 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000003061 126.0
LZS1_k127_7923590_4 glycosyl transferase group 1 - - - 0.0000000000000000000000001416 124.0
LZS1_k127_7923590_5 transferase activity, transferring glycosyl groups K19002 - 2.4.1.337 0.00000000000000000007746 105.0
LZS1_k127_7923590_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000158 89.0
LZS1_k127_801652_0 PFAM Extradiol ring-cleavage dioxygenase, class III - - - 0.0000000000000000000000000000000000000003417 159.0
LZS1_k127_801652_1 hydrolase, family 25 - - - 0.00000000000004336 85.0
LZS1_k127_801652_2 Glycosyltransferase like family - - - 0.00000116 61.0
LZS1_k127_806932_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.612e-203 647.0
LZS1_k127_806932_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000002146 121.0
LZS1_k127_806932_2 TM2 domain - - - 0.0000000000000000000007485 104.0
LZS1_k127_806932_3 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000007743 94.0
LZS1_k127_806932_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000004459 80.0
LZS1_k127_806932_5 Dienelactone hydrolase family - - - 0.0000000007993 60.0
LZS1_k127_806932_6 -O-antigen K02847 - - 0.0002902 53.0
LZS1_k127_8079867_0 Belongs to the FtsK SpoIIIE SftA family K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006679 487.0
LZS1_k127_8079867_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 439.0
LZS1_k127_8079867_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000001455 102.0
LZS1_k127_8079867_3 PFAM S23 ribosomal protein - - - 0.000009327 55.0
LZS1_k127_8079867_4 Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein. - - - 0.00008255 53.0
LZS1_k127_8079867_5 Domain of unknown function (DUF4115) K15539 - - 0.0001485 52.0
LZS1_k127_8079867_6 Potential Monad-binding region of RPAP3 K00237 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0010941,GO:0030544,GO:0031072,GO:0032991,GO:0042752,GO:0042981,GO:0043066,GO:0043067,GO:0043069,GO:0043523,GO:0043524,GO:0044424,GO:0044444,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050795,GO:0051879,GO:0060548,GO:0065007,GO:0097255,GO:1901214,GO:1901215,GO:1904059,GO:2000671,GO:2000672 - 0.0006325 50.0
LZS1_k127_8080958_0 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000002136 235.0
LZS1_k127_8080958_1 impB/mucB/samB family C-terminal domain K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000002459 187.0
LZS1_k127_824312_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 352.0
LZS1_k127_824312_1 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000515 130.0
LZS1_k127_824312_2 NlpC/P60 family - - - 0.000004855 57.0
LZS1_k127_905835_0 Cell division protein FtsA K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004711 386.0
LZS1_k127_905835_1 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000001615 180.0
LZS1_k127_905835_2 Protein of unknown function (DUF4012) - - - 0.00000000000000000000000000000000000003441 164.0
LZS1_k127_905835_3 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000005909 136.0
LZS1_k127_9530_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 333.0
LZS1_k127_9530_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 321.0
LZS1_k127_9530_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000001197 136.0
LZS1_k127_9530_4 self proteolysis - - - 0.000000000000000000003667 109.0
LZS1_k127_9530_5 AbrB family - - - 0.000002823 52.0