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Overview

ID MAG02224
Name LZS2_bin.7
Sample SMP0056
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Nitrososphaeria
Order Nitrososphaerales
Family Nitrosopumilaceae
Genus Nitrosopumilus
Species
Assembly information
Completeness (%) 70.13
Contamination (%) 2.74
GC content (%) 33.0
N50 (bp) 4,137
Genome size (bp) 1,181,494

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1511

Gene name Description KEGG GOs EC E-value Score Sequence
LZS2_k127_1001242_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 1.489e-281 869.0
LZS2_k127_1004187_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006171 371.0
LZS2_k127_1004187_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001306 254.0
LZS2_k127_1004187_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000000000000000000000000000009327 168.0
LZS2_k127_101134_0 DEAD DEAH box helicase K05592 - 3.6.4.13 1.251e-205 641.0
LZS2_k127_101134_1 COG1651 Protein-disulfide isomerase K21990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 445.0
LZS2_k127_101134_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 358.0
LZS2_k127_101134_3 - - - - 0.00000000000000000000000000000000001964 135.0
LZS2_k127_101134_5 - - - - 0.0000000000001013 71.0
LZS2_k127_102377_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.965e-267 825.0
LZS2_k127_102377_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 450.0
LZS2_k127_102377_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000133 121.0
LZS2_k127_107147_0 TIGRFAM urea ABC transporter, urea binding protein K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 540.0
LZS2_k127_107147_1 RNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 431.0
LZS2_k127_107147_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 307.0
LZS2_k127_107147_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000005494 212.0
LZS2_k127_107147_4 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000005061 218.0
LZS2_k127_107147_5 Rieske 2Fe-2S K05710 - - 0.0000000000000000000000000000000000000000000000000000008798 192.0
LZS2_k127_107147_6 Mg2 transporter protein K03284 - - 0.000000000000000000000000000000000000000000005589 164.0
LZS2_k127_107147_7 Belongs to the UPF0147 family K09721 - - 0.00000000000000000000000000000000000000002185 154.0
LZS2_k127_1105231_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 7.368e-230 713.0
LZS2_k127_1105231_1 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000003518 229.0
LZS2_k127_1116559_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 571.0
LZS2_k127_1116559_1 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000001679 171.0
LZS2_k127_1116559_2 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000422 173.0
LZS2_k127_1116559_3 - - - - 0.000000000000000000000004443 107.0
LZS2_k127_1122207_0 CBS domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 326.0
LZS2_k127_1122207_1 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000008343 225.0
LZS2_k127_1122207_2 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000003458 189.0
LZS2_k127_1122207_3 CBS domain - - - 0.000000000000000000000000000000000000000000000003294 175.0
LZS2_k127_1148417_0 3-isopropylmalate dehydratase, large subunit K01703 - 4.2.1.33,4.2.1.35 2.739e-300 923.0
LZS2_k127_1148417_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 9.777e-260 802.0
LZS2_k127_1148417_10 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 292.0
LZS2_k127_1148417_11 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001878 258.0
LZS2_k127_1148417_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000003872 230.0
LZS2_k127_1148417_13 - - - - 0.0000000000000000000000000000000000000000000000000000000006093 202.0
LZS2_k127_1148417_14 - - - - 0.000000000000000000000000000000000000000000000009051 171.0
LZS2_k127_1148417_15 - - - - 0.00000000000000000000004654 99.0
LZS2_k127_1148417_16 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000001417 84.0
LZS2_k127_1148417_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 444.0
LZS2_k127_1148417_3 F420-0:Gamma-glutamyl ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 436.0
LZS2_k127_1148417_4 PFAM Nucleotidyl transferase K00966,K03430 - 2.6.1.37,2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 411.0
LZS2_k127_1148417_5 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 410.0
LZS2_k127_1148417_6 DNA-directed RNA polymerase, alpha subunit 40 kD subunit K03047 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 398.0
LZS2_k127_1148417_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 351.0
LZS2_k127_1148417_8 3-isopropylmalate dehydratase, small subunit K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 320.0
LZS2_k127_1148417_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 312.0
LZS2_k127_1157034_0 UbiD family decarboxylase K03182 - 4.1.1.98 1.234e-303 932.0
LZS2_k127_1157034_1 Chorismate mutase type II K00812 - 2.6.1.1 3.347e-252 782.0
LZS2_k127_1157034_10 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 379.0
LZS2_k127_1157034_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004927 269.0
LZS2_k127_1157034_12 GHMP kinases N terminal domain K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000004786 247.0
LZS2_k127_1157034_13 - - - - 0.00000000000000000000000000000006249 125.0
LZS2_k127_1157034_14 NUDIX domain - - - 0.000000000000000008313 88.0
LZS2_k127_1157034_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 4.224e-234 728.0
LZS2_k127_1157034_3 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) - - - 3.396e-233 724.0
LZS2_k127_1157034_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 1.679e-215 671.0
LZS2_k127_1157034_5 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 3.612e-212 661.0
LZS2_k127_1157034_6 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 547.0
LZS2_k127_1157034_7 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 516.0
LZS2_k127_1157034_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 479.0
LZS2_k127_1157034_9 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 435.0
LZS2_k127_1194977_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 7.601e-305 938.0
LZS2_k127_1194977_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 4.656e-212 662.0
LZS2_k127_1194977_10 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000001514 188.0
LZS2_k127_1194977_11 - - - - 0.000000000000000000000000000000000000000000000003294 175.0
LZS2_k127_1194977_12 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000003279 164.0
LZS2_k127_1194977_14 4-hydroxybenzoate synthetase (chorismate lyase) K03181,K06984 - 2.4.2.54,4.1.3.40 0.000000000000000000001021 101.0
LZS2_k127_1194977_15 COG1522 Transcriptional regulators - - - 0.0000000000000000007824 88.0
LZS2_k127_1194977_16 - - - - 0.00000000000000003821 83.0
LZS2_k127_1194977_17 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette K15342 - - 0.000000000000002608 76.0
LZS2_k127_1194977_19 PFAM Uncharacterised protein family UPF0150 - - - 0.000000006634 59.0
LZS2_k127_1194977_2 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 490.0
LZS2_k127_1194977_20 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000184 48.0
LZS2_k127_1194977_4 antibiotic catabolic process K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 289.0
LZS2_k127_1194977_5 Peptidyl-tRNA hydrolase PTH2 K04794 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000001529 245.0
LZS2_k127_1194977_6 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009668 241.0
LZS2_k127_1194977_7 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000002175 242.0
LZS2_k127_1194977_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002376 229.0
LZS2_k127_1194977_9 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000000000000000000001354 183.0
LZS2_k127_1199405_0 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 7.534e-225 698.0
LZS2_k127_1199405_1 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 496.0
LZS2_k127_1199405_2 Lysine biosynthesis K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 426.0
LZS2_k127_1199405_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.00000000000000000000000000000000000000000000000000000000003437 208.0
LZS2_k127_1243182_0 cytochrome-c peroxidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 403.0
LZS2_k127_1243182_1 Methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 381.0
LZS2_k127_1243182_2 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 290.0
LZS2_k127_1243182_3 Belongs to the ribosomal protein L31e family K02910 - - 0.00000000000000000000000000000000000000000000000002846 179.0
LZS2_k127_1243182_4 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.00000000000000000000001877 99.0
LZS2_k127_1246784_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 9.833e-265 817.0
LZS2_k127_1246784_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 481.0
LZS2_k127_1246784_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 409.0
LZS2_k127_1246784_3 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 365.0
LZS2_k127_1246784_4 - - - - 0.000000000000000000000000000000000000000000000000002921 184.0
LZS2_k127_1246784_5 - - - - 0.0000000000000000000000000000000000000000000001319 169.0
LZS2_k127_1246784_6 Cysteine synthase K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000001947 158.0
LZS2_k127_1246784_7 redox protein, regulator of disulfide bond formation - - - 0.0000000000000000000000000000000000000003178 149.0
LZS2_k127_1246784_8 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K07646,K20989 - 2.7.13.3 0.000000000004851 66.0
LZS2_k127_1260940_0 DHHA1 domain K07463 - - 1.889e-284 876.0
LZS2_k127_1260940_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.428e-250 775.0
LZS2_k127_1260940_2 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 387.0
LZS2_k127_1260940_3 ribosomal protein K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008371 276.0
LZS2_k127_1260940_4 RNA binding K07581 - - 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
LZS2_k127_1260940_5 - - - - 0.000000000000000000001078 95.0
LZS2_k127_137278_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0 1060.0
LZS2_k127_137278_1 Belongs to the phosphohexose mutase family K15778 - 5.4.2.2,5.4.2.8 8.716e-255 789.0
LZS2_k127_137278_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000003077 259.0
LZS2_k127_137278_3 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003943 258.0
LZS2_k127_137278_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001968 242.0
LZS2_k127_137278_5 Binds to the 23S rRNA K02896 - - 0.00000000000000000000000000000000028 132.0
LZS2_k127_137278_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000000005579 116.0
LZS2_k127_137278_7 acid phosphatase activity - - - 0.0000000000000000000005847 97.0
LZS2_k127_1375636_0 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 1.389e-222 691.0
LZS2_k127_1375636_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 604.0
LZS2_k127_1375636_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 414.0
LZS2_k127_1375636_3 copper ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001529 255.0
LZS2_k127_1375636_4 - - - - 0.00000000000000000000000000000000000000000007749 160.0
LZS2_k127_1375636_5 Mg2 transporter protein K03284 - - 0.00000000002032 64.0
LZS2_k127_1396975_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 7.26e-231 715.0
LZS2_k127_1396975_1 Phenylalanyl-tRNA synthetase alpha subunit K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002609 511.0
LZS2_k127_1396975_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 374.0
LZS2_k127_1396975_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000001308 218.0
LZS2_k127_1396975_4 Cytidylyltransferase-like K02201 - 2.7.7.3 0.0000000000000000000000000000000000000000111 154.0
LZS2_k127_1396975_5 - - - - 0.0000000000000000000000000000000000000001236 151.0
LZS2_k127_1454833_0 - - - - 1.878e-223 694.0
LZS2_k127_1454833_1 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 537.0
LZS2_k127_1454833_2 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 473.0
LZS2_k127_1454833_3 ATPase family associated with various cellular activities (AAA) K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002689 268.0
LZS2_k127_1455715_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 3.703e-201 630.0
LZS2_k127_1455715_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 586.0
LZS2_k127_1455715_2 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009994 537.0
LZS2_k127_1455715_3 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 402.0
LZS2_k127_1455715_4 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 296.0
LZS2_k127_1455715_5 Alba K03622 - - 0.000000000000000000000000000000000000000000000000000000000000000017 229.0
LZS2_k127_1455715_6 - - - - 0.000000000000000000000000000000000000000000000000000000000001833 209.0
LZS2_k127_1455715_7 - - - - 0.000000000000000000000000000000000001227 139.0
LZS2_k127_1455715_8 - - - - 0.000000000000002502 78.0
LZS2_k127_146597_0 Catalyzes the NAD(P)( )-dependent oxidation of D-glucose to D-gluconate via gluconolactone. Can utilize both NAD( ) and NADP( ) as electron acceptor. Is involved in the degradation of glucose through a K00001 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 567.0
LZS2_k127_146597_1 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007287 247.0
LZS2_k127_146597_2 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.0000000000000000000000000000000000000000000000000000000008916 202.0
LZS2_k127_146597_3 acid phosphatase activity - - - 0.000000209 54.0
LZS2_k127_1476418_0 - - - - 1.736e-249 775.0
LZS2_k127_1476418_1 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 377.0
LZS2_k127_1476418_2 Periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 325.0
LZS2_k127_1476418_3 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008526 246.0
LZS2_k127_1477696_0 Protein of unknown function (DUF521) K09123 - - 1.841e-225 701.0
LZS2_k127_1477696_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 375.0
LZS2_k127_1477696_2 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000000000000000000000001687 196.0
LZS2_k127_1477696_4 conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000000000001117 160.0
LZS2_k127_1477696_5 cellulase activity - - - 0.00000000000000000000000000000000001272 158.0
LZS2_k127_1477696_6 - - - - 0.000000000000000000003194 93.0
LZS2_k127_1477696_7 COG3419 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.000000000000000001025 102.0
LZS2_k127_1477696_8 - - - - 0.00000004169 63.0
LZS2_k127_148996_0 RNA-metabolising metallo-beta-lactamase K07041 - - 0.0 1247.0
LZS2_k127_148996_1 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 322.0
LZS2_k127_1510560_0 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 533.0
LZS2_k127_1510560_1 RNA secondary structure unwinding - - - 0.000000000000000000000000000000000000000000000000001122 187.0
LZS2_k127_1510560_2 - - - - 0.000000003335 57.0
LZS2_k127_1538131_0 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 1.992e-305 941.0
LZS2_k127_1538131_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.0000000000000000000000000000000000000000000000000000003409 199.0
LZS2_k127_1550774_0 Amino acid kinase family K00928 - 2.7.2.4 1.938e-256 795.0
LZS2_k127_1550774_1 Histidine kinase - - - 1.818e-249 782.0
LZS2_k127_1550774_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 578.0
LZS2_k127_1550774_3 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 311.0
LZS2_k127_1550774_4 Glycosyltransferase family 28 C-terminal domain - - - 0.00000000000000000000000000000000000000000000000002768 180.0
LZS2_k127_1550774_5 COG0784 FOG CheY-like receiver K02485,K02490,K03413 - - 0.000000000000000000000000000000003824 130.0
LZS2_k127_1550774_6 - - - - 0.0000000000000000000000000000002382 123.0
LZS2_k127_1550774_7 - - - - 0.00000000000000000000000000004488 117.0
LZS2_k127_1647424_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005403 436.0
LZS2_k127_1647424_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 379.0
LZS2_k127_1647424_2 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 295.0
LZS2_k127_1647424_3 aspartate carbamoyltransferase K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000021 198.0
LZS2_k127_1647424_4 ATP synthase subunit C K02110,K02124 - - 0.00000000000000000000000000000000000000000009175 160.0
LZS2_k127_1649303_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 576.0
LZS2_k127_1649303_1 - - - - 0.00000007723 56.0
LZS2_k127_1649303_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000009652 51.0
LZS2_k127_1716701_0 Required for chromosome condensation and partitioning - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 595.0
LZS2_k127_1716701_1 - - - - 0.0000000000000000000000000000000000000000000000000000000008022 203.0
LZS2_k127_17188_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1309.0
LZS2_k127_17188_1 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.000000000000000000000000000000000000000000000000000000000000000000241 231.0
LZS2_k127_17188_2 - - - - 0.0000000000000000000000000001707 115.0
LZS2_k127_1763471_0 aconitate hydratase K01681 - 4.2.1.3 0.0 1385.0
LZS2_k127_1763471_1 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 0.0 1022.0
LZS2_k127_1763471_2 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 599.0
LZS2_k127_1763471_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 364.0
LZS2_k127_1763471_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 310.0
LZS2_k127_1763471_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 300.0
LZS2_k127_1763471_6 - - - - 0.00000000000000000000000000000000015 141.0
LZS2_k127_1763471_7 protein secretion by the type IV secretion system - - - 0.0000000000000000000001377 110.0
LZS2_k127_1778664_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 1.089e-320 982.0
LZS2_k127_1778664_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 517.0
LZS2_k127_177868_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 480.0
LZS2_k127_177868_1 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 421.0
LZS2_k127_177868_2 PhoU domain K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 371.0
LZS2_k127_177868_3 Cyclophilin-like K09143 - - 0.000000000248 61.0
LZS2_k127_1782715_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 1.61e-231 722.0
LZS2_k127_1782715_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 331.0
LZS2_k127_1782715_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001961 272.0
LZS2_k127_1782715_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001149 235.0
LZS2_k127_1782715_4 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000001232 222.0
LZS2_k127_1782715_5 Belongs to the UPF0201 family K09736 - - 0.000000000000000000000000000000000000000000000000000000000002488 211.0
LZS2_k127_1782715_6 serine threonine protein kinase K07176 - - 0.00000000000000000000000000000001082 136.0
LZS2_k127_1782715_7 - - - - 0.00000000000000000000000368 102.0
LZS2_k127_1800972_0 extracellular matrix structural constituent - - - 1.172e-226 707.0
LZS2_k127_1800972_1 FtsX-like permease family K09808 - - 2.083e-221 691.0
LZS2_k127_1800972_2 ABC-type antimicrobial peptide transport system, ATPase component K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008099 361.0
LZS2_k127_1800972_3 AsnC-type helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 356.0
LZS2_k127_1800972_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001444 222.0
LZS2_k127_1800972_5 ABC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000003495 221.0
LZS2_k127_1800972_6 - - - - 0.0000000000000000000000000000000000000001143 153.0
LZS2_k127_18364_0 Belongs to the RtcB family K14415 - 6.5.1.3 1.206e-299 921.0
LZS2_k127_18364_1 adenylosuccinate lyase K01756 - 4.3.2.2 5.598e-266 822.0
LZS2_k127_18364_2 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006939 409.0
LZS2_k127_18364_3 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 284.0
LZS2_k127_18364_4 - - - - 0.0000000000000000000000000000000000000000000000000000003207 196.0
LZS2_k127_18364_5 - - - - 0.0000000000000000000000000000000000000000000000000008372 184.0
LZS2_k127_18364_6 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000000000000000000000008099 177.0
LZS2_k127_18364_7 - - - - 0.0000000000000000000000000000000000000000007774 158.0
LZS2_k127_18364_8 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000001014 119.0
LZS2_k127_1859963_0 PFAM Multicopper oxidase - - - 1.714e-209 653.0
LZS2_k127_1859963_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001229 213.0
LZS2_k127_187703_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 7.086e-317 974.0
LZS2_k127_187703_1 - - - - 1.093e-194 612.0
LZS2_k127_187703_2 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004982 534.0
LZS2_k127_187703_3 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 526.0
LZS2_k127_187703_4 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005394 491.0
LZS2_k127_187703_6 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
LZS2_k127_187703_7 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase K07329 - - 0.000000000000000000000000000000003953 130.0
LZS2_k127_1906047_0 Pterin binding enzyme K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 455.0
LZS2_k127_1906047_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 410.0
LZS2_k127_1907555_0 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 558.0
LZS2_k127_1907555_1 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 301.0
LZS2_k127_1907555_2 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.000000000000000000000000003668 112.0
LZS2_k127_1941405_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 6.755e-240 741.0
LZS2_k127_1941405_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003497 256.0
LZS2_k127_199170_0 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 406.0
LZS2_k127_199170_1 - - - - 0.00000000000000000000000000000000000000000002767 162.0
LZS2_k127_199170_2 - - - - 0.000000000000000003855 87.0
LZS2_k127_199170_3 - - - - 0.000000000003587 68.0
LZS2_k127_2017674_0 SMC proteins Flexible Hinge Domain K03529 - - 0.0 1888.0
LZS2_k127_2133858_0 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000002532 217.0
LZS2_k127_2133858_1 Bacterial PH domain - - - 0.00000000000000000000000000000000000000000006735 164.0
LZS2_k127_2133858_2 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.00000000000000000000000000000053 124.0
LZS2_k127_2133858_3 - - - - 0.0000000000000000000829 96.0
LZS2_k127_2218498_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 395.0
LZS2_k127_2218498_1 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 327.0
LZS2_k127_2218498_2 Met-10+ like-protein K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 288.0
LZS2_k127_2218498_3 HTH DNA binding domain - - - 0.0000000000000000000000000000000000003365 140.0
LZS2_k127_2238285_0 TCP-1/cpn60 chaperonin family K22447 - - 3.95e-322 989.0
LZS2_k127_2238285_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 570.0
LZS2_k127_2238285_2 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 522.0
LZS2_k127_2238285_3 - - - - 0.0000000000000000000000000000000000000000000000000000005886 194.0
LZS2_k127_2238285_4 Domain of unknown function (DUF2024) - - - 0.00000000000000000000000000000000000000000000004511 170.0
LZS2_k127_2260746_0 - - - - 2.467e-215 676.0
LZS2_k127_2260746_1 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 284.0
LZS2_k127_2260746_2 - - - - 0.0000000000000002336 79.0
LZS2_k127_2267951_0 Peptidase family M1 domain K01256,K13722 - 3.4.11.2 0.0 1541.0
LZS2_k127_2267951_1 LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 533.0
LZS2_k127_2267951_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 514.0
LZS2_k127_2267951_3 - - - - 0.0000000000000000000004096 100.0
LZS2_k127_2267951_4 - - - - 0.00000000002368 63.0
LZS2_k127_2268073_0 NOSIC (NUC001) domain K14564 - - 6.39e-230 716.0
LZS2_k127_2268073_1 Catalyzes the conversion of dihydroorotate to orotate K00226,K00254,K17723,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.1,1.3.1.14,1.3.5.2,1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 561.0
LZS2_k127_2268073_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 404.0
LZS2_k127_2268073_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 336.0
LZS2_k127_2268073_4 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 - 2.1.1.215,2.1.1.216 0.000000003735 58.0
LZS2_k127_2268842_0 Trypsin-like serine protease with C-terminal PDZ domain - - - 4.948e-197 619.0
LZS2_k127_2268842_1 PFAM Glycosyl transferase family 2 K07011,K11936 - - 0.0000000000000000000000000000000000000000000000000000000000000102 218.0
LZS2_k127_2268842_2 Radical SAM K11780 - 2.5.1.77 0.000000000000000000000000000000001735 130.0
LZS2_k127_2284310_0 Radical SAM - - - 0.0 1086.0
LZS2_k127_2284310_1 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 578.0
LZS2_k127_2284310_2 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 452.0
LZS2_k127_2284310_3 protein secretion by the type IV secretion system - - - 0.000000000000000000000000000000000000000000000000000000000000003361 221.0
LZS2_k127_2284310_4 - - - - 0.0000000000000000000000000000000000000000000000000000000006265 202.0
LZS2_k127_2314533_0 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 553.0
LZS2_k127_2314533_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 430.0
LZS2_k127_2344297_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 3.448e-212 661.0
LZS2_k127_2344297_1 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 474.0
LZS2_k127_2344297_2 - - - - 0.0000000000000000000000000000000000000000000000000000000006265 202.0
LZS2_k127_2380330_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1336.0
LZS2_k127_241443_0 CAAX protease self-immunity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 441.0
LZS2_k127_241443_1 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000000000000001155 209.0
LZS2_k127_241443_2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.000000000000000000000000000000000000000004155 156.0
LZS2_k127_2431667_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 1.659e-206 644.0
LZS2_k127_2431667_1 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002072 340.0
LZS2_k127_2431667_2 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 326.0
LZS2_k127_2431667_3 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006069 258.0
LZS2_k127_2431667_4 - - - - 0.000000000000000000000000000000000000000000000000000000000003887 213.0
LZS2_k127_2445348_0 DNA polymerase K02319 - 2.7.7.7 0.0 1596.0
LZS2_k127_2445348_1 DEAD DEAH box helicase domain protein K03703,K10896 - - 3.161e-233 725.0
LZS2_k127_2445348_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 368.0
LZS2_k127_2445348_3 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 347.0
LZS2_k127_2445348_4 Sugar efflux transporter for intercellular exchange K15383 - - 0.0000000000000000000000000000000000000000001773 159.0
LZS2_k127_2450059_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001149 273.0
LZS2_k127_2450059_1 UbiD family decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005561 250.0
LZS2_k127_2450059_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002109 239.0
LZS2_k127_2450059_3 - - - - 0.0000000000000000000000001085 110.0
LZS2_k127_2483771_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 2.191e-244 757.0
LZS2_k127_2483771_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000005553 157.0
LZS2_k127_2509491_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 584.0
LZS2_k127_2509491_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 346.0
LZS2_k127_2509491_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002088 270.0
LZS2_k127_2509491_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003568 233.0
LZS2_k127_2509491_4 - - - - 0.000000000000000000000000000000000000000000000000000000000003108 210.0
LZS2_k127_2509491_5 - - - - 0.00000000000000000000001755 101.0
LZS2_k127_2539858_0 DNA primase K02316 - - 9.152e-222 691.0
LZS2_k127_2539858_1 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008177 410.0
LZS2_k127_2539858_2 Iron-sulfur cluster assembly accessory protein K13628 - - 0.00000000000000000000000000000000000000000000000000000000000001383 215.0
LZS2_k127_2539858_3 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.00000000000000000000000000000000000000000000000000000000005382 205.0
LZS2_k127_254695_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006044 472.0
LZS2_k127_254695_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002534 213.0
LZS2_k127_254695_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000005061 190.0
LZS2_k127_254695_3 - - - - 0.000000000000005762 74.0
LZS2_k127_254695_4 Pyridoxamine 5'-phosphate K07005 - - 0.00000000003419 66.0
LZS2_k127_2555416_0 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 411.0
LZS2_k127_2555416_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 397.0
LZS2_k127_2555416_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 373.0
LZS2_k127_2555416_3 SNF2 family N-terminal domain - - - 0.00000000565 57.0
LZS2_k127_257200_0 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001847 273.0
LZS2_k127_257200_1 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003365 233.0
LZS2_k127_257200_2 - - - - 0.0000000000000000000000000000000000000000000000000002543 185.0
LZS2_k127_257200_3 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000003568 132.0
LZS2_k127_257200_4 DEAD DEAH box helicase K05592 - 3.6.4.13 0.000000000000000000000000000000001431 130.0
LZS2_k127_257200_5 CDGSH-type zinc finger. Function unknown. - - - 0.00000000000141 68.0
LZS2_k127_2630506_0 fumarate reductase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.0 1136.0
LZS2_k127_2630506_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 312.0
LZS2_k127_2630506_2 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000152 274.0
LZS2_k127_2630506_3 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000000000000000000000000000000000001002 207.0
LZS2_k127_2630506_4 Phosphoenolpyruvate phosphomutase - - - 0.0000003026 51.0
LZS2_k127_263612_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001458 281.0
LZS2_k127_263612_1 - - - - 0.000000000000000000000000000000000000000000000000000000000002136 210.0
LZS2_k127_263612_2 - - - - 0.00000000000000000000000000000000000000000000000004178 179.0
LZS2_k127_263612_3 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000001051 118.0
LZS2_k127_263612_4 ATPase involved in DNA repair - - - 0.000000001964 59.0
LZS2_k127_2637309_0 FAD dependent oxidoreductase K15736 - - 2.853e-225 703.0
LZS2_k127_2637309_1 D-isomer specific 2-hydroxyacid dehydrogenase K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006709 399.0
LZS2_k127_2637309_2 - - - - 0.00000000000000000000000000000000000000000000000000007706 186.0
LZS2_k127_2637309_3 Haem utilisation ChuX/HutX - - - 0.00000000000000000000000000000000000000000000000002855 181.0
LZS2_k127_2660168_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.735e-284 877.0
LZS2_k127_2660168_1 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 512.0
LZS2_k127_2660168_2 Belongs to the universal ribosomal protein uS5 family K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 452.0
LZS2_k127_2660168_3 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 296.0
LZS2_k127_2660168_4 ribosomal protein K02907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001246 270.0
LZS2_k127_2660168_5 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005013 241.0
LZS2_k127_2660168_6 Belongs to the archaeal adenylate kinase family K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000001373 180.0
LZS2_k127_2660168_7 membrane - - - 0.0000000000000000000000000000000000000000000003206 168.0
LZS2_k127_271614_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.698e-219 685.0
LZS2_k127_271614_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 289.0
LZS2_k127_271614_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000001222 270.0
LZS2_k127_271614_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000002026 216.0
LZS2_k127_271614_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000000000000000000000000000000000002952 194.0
LZS2_k127_271614_5 - - - - 0.000000000000007958 78.0
LZS2_k127_271614_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000009628 63.0
LZS2_k127_2781405_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 481.0
LZS2_k127_2781405_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000003652 224.0
LZS2_k127_281420_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003058 273.0
LZS2_k127_281420_1 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 233.0
LZS2_k127_281420_2 - - - - 0.00000000000000000000000000000000000000000000000000000000004636 205.0
LZS2_k127_281420_3 - - - - 0.00000000000000000000000000000000000000000000008905 169.0
LZS2_k127_281420_4 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.0000005415 51.0
LZS2_k127_281725_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1e-215 671.0
LZS2_k127_281725_1 regulatory protein, arsR - - - 0.0000000000000000000000000000000000000000000000000000000000000009605 220.0
LZS2_k127_2853771_0 Peptidase M10A and M12B matrixin and adamalysin - - - 0.0000000000000000000000000000000000000000000000000006114 196.0
LZS2_k127_2853771_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000002167 179.0
LZS2_k127_2853771_2 Lamin Tail Domain - - - 0.000000000000000000000000000000004035 132.0
LZS2_k127_288090_0 Pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1203.0
LZS2_k127_288090_1 Helix-turn-helix XRE-family like proteins - - - 0.0001011 44.0
LZS2_k127_2891915_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 407.0
LZS2_k127_2891915_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000003428 231.0
LZS2_k127_2891915_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.00000000000000000000000000000000000000000000000000000000000000001394 226.0
LZS2_k127_2937555_0 Belongs to the peptidase S8 family K14647 - - 0.0 1021.0
LZS2_k127_2937555_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.235e-319 981.0
LZS2_k127_2937555_10 ribosomal protein K02912 - - 0.0000000000000000000000000000000000000001105 155.0
LZS2_k127_2937555_11 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.00000000000000000000000004481 107.0
LZS2_k127_2937555_12 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000001132 110.0
LZS2_k127_2937555_2 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 437.0
LZS2_k127_2937555_3 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 370.0
LZS2_k127_2937555_4 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 295.0
LZS2_k127_2937555_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 289.0
LZS2_k127_2937555_6 helix_turn_helix ASNC type K03718 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 283.0
LZS2_k127_2937555_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 280.0
LZS2_k127_2937555_8 Binds to the 23S rRNA K02885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003059 271.0
LZS2_k127_2937555_9 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000004596 181.0
LZS2_k127_3084420_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 541.0
LZS2_k127_3084420_1 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 522.0
LZS2_k127_3102617_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 3.086e-259 800.0
LZS2_k127_3102617_1 SUF system FeS assembly protein K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 286.0
LZS2_k127_3102617_2 Bacterial extracellular solute-binding protein K10117 - - 0.000000000000000000000000000000000000000000000000000000000000000006744 231.0
LZS2_k127_3102617_3 - - - - 0.0000000000000000000000000000000000000000000000000000002281 195.0
LZS2_k127_3102617_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000002445 78.0
LZS2_k127_314798_0 DEAD/H associated K03724 - - 5.587e-287 885.0
LZS2_k127_314798_1 S-adenosylmethionine synthetase K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 545.0
LZS2_k127_314798_2 RecA RadA K04482,K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 377.0
LZS2_k127_314798_3 snRNP Sm proteins K04796 - - 0.000000000000000000000000000000000000000003209 156.0
LZS2_k127_3161697_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 2.381e-251 779.0
LZS2_k127_3161697_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 1.34e-202 635.0
LZS2_k127_3161697_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 474.0
LZS2_k127_3161697_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 434.0
LZS2_k127_3161697_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 339.0
LZS2_k127_3161697_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000004249 215.0
LZS2_k127_3214982_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 435.0
LZS2_k127_3214982_1 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 334.0
LZS2_k127_3214982_2 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000016 123.0
LZS2_k127_326648_0 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 380.0
LZS2_k127_326648_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001597 249.0
LZS2_k127_326648_2 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000009242 143.0
LZS2_k127_326648_3 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000000000000000000002434 131.0
LZS2_k127_333350_0 - - - - 0.0 1562.0
LZS2_k127_333350_1 geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 3.229e-231 719.0
LZS2_k127_333350_12 - - - - 0.0000009429 53.0
LZS2_k127_333350_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 465.0
LZS2_k127_333350_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 456.0
LZS2_k127_333350_4 DSBA oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 377.0
LZS2_k127_333350_5 Protein of unknown function (DUF1698) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 348.0
LZS2_k127_333350_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005905 249.0
LZS2_k127_333350_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007656 241.0
LZS2_k127_333350_8 zinc finger - - - 0.00000000000000000000000000000000000000000000000007367 179.0
LZS2_k127_333350_9 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000002899 140.0
LZS2_k127_3355634_0 Aminotransferase class-V - - - 8.012e-236 730.0
LZS2_k127_3355634_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 6.446e-211 657.0
LZS2_k127_3355634_2 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 466.0
LZS2_k127_3360592_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1202.0
LZS2_k127_3360592_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000002587 87.0
LZS2_k127_3363609_0 Protein of unknown function DUF111 K09121 - 4.99.1.12 6.557e-208 651.0
LZS2_k127_3363609_1 tRNA methyl transferase K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 464.0
LZS2_k127_3363609_2 Cysteine desulfurase K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 467.0
LZS2_k127_3363609_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 368.0
LZS2_k127_3363609_4 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000009564 56.0
LZS2_k127_3364942_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 0.0 1800.0
LZS2_k127_3364942_1 Belongs to the GARS family K01945 - 6.3.4.13 1.027e-238 741.0
LZS2_k127_3364942_2 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.000003752 49.0
LZS2_k127_3369734_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 340.0
LZS2_k127_3369734_1 Transposase K07483 - - 0.000000000000000009174 87.0
LZS2_k127_3369734_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000002467 84.0
LZS2_k127_3370254_0 COG1651 Protein-disulfide isomerase K21990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 360.0
LZS2_k127_3370254_1 antibiotic catabolic process K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 301.0
LZS2_k127_3370254_2 Archaeal TRASH domain - - - 0.00000000000000000000000000000000002883 139.0
LZS2_k127_3370254_3 YHS domain - - - 0.0000000007944 60.0
LZS2_k127_3385745_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 412.0
LZS2_k127_3385745_1 sister chromatid segregation - - - 0.000006434 48.0
LZS2_k127_3392884_0 PFAM Aldehyde dehydrogenase K00135,K18601 - 1.2.1.16,1.2.1.20,1.2.1.79 1.28e-248 768.0
LZS2_k127_3392884_1 Hemerythrin HHE cation binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 332.0
LZS2_k127_3392884_2 - - - - 0.00000000000000000000000000000000001701 136.0
LZS2_k127_3392884_3 - - - - 0.0000000000000000000000000000000003502 133.0
LZS2_k127_3392884_4 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000002156 117.0
LZS2_k127_3394592_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001091 272.0
LZS2_k127_3394592_1 - - - - 0.0000000000000000000000000000000005274 132.0
LZS2_k127_3394592_2 - - - - 0.00000000000000000000001549 100.0
LZS2_k127_3394592_3 - - - - 0.00000000000000000000005509 100.0
LZS2_k127_3401007_0 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 - 2.1.1.260 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 374.0
LZS2_k127_3401007_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 359.0
LZS2_k127_3401007_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000000000000000000000000000000000000007842 178.0
LZS2_k127_3401007_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000009237 127.0
LZS2_k127_3403651_0 Glycosyl transferase family group 2 - - - 0.0 1090.0
LZS2_k127_3403651_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 5.136e-194 606.0
LZS2_k127_3403651_2 ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 597.0
LZS2_k127_3403651_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 488.0
LZS2_k127_3403651_4 ERCC4 domain K10848 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 403.0
LZS2_k127_3403651_5 - - - - 0.0000000000000000000000000000000000000000000000000000005406 193.0
LZS2_k127_3403651_6 ribonuclease activity K07060 - - 0.0000000000000000000009599 100.0
LZS2_k127_3403651_7 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000000000000006047 90.0
LZS2_k127_3410911_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 0.0 1021.0
LZS2_k127_3410911_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.4e-322 987.0
LZS2_k127_3410911_2 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.197e-216 673.0
LZS2_k127_3410911_3 - - - - 0.0000000000000000000000000000000000000001147 151.0
LZS2_k127_3415310_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.781e-199 623.0
LZS2_k127_3415310_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000004417 160.0
LZS2_k127_3418791_0 Replication factor C K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 576.0
LZS2_k127_3418791_1 PFAM 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 368.0
LZS2_k127_3427282_0 SNF2 family N-terminal domain - - - 0.0 1092.0
LZS2_k127_3427282_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003401 278.0
LZS2_k127_3427282_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000001067 141.0
LZS2_k127_3427282_3 PAC2 family K07159 - - 0.0001919 44.0
LZS2_k127_3433796_0 Fumarase C C-terminus K01744 - 4.3.1.1 5.14e-266 822.0
LZS2_k127_3433796_1 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 1.598e-259 801.0
LZS2_k127_3433796_2 Tubulin/FtsZ family, GTPase domain K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005442 245.0
LZS2_k127_3433796_3 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000175 168.0
LZS2_k127_3437969_0 Calcineurin-like phosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000625 411.0
LZS2_k127_3437969_1 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003736 273.0
LZS2_k127_3437969_2 ATP synthase (F/14-kDa) subunit K02122 - - 0.00000000000000000000000000000000000000000000000000000000001051 207.0
LZS2_k127_3437969_3 - - - - 0.00000000000000000000000000000000000000000000000000009156 186.0
LZS2_k127_3437969_4 - - - - 0.00000000000000000000000000000000000000000000000001794 180.0
LZS2_k127_3437969_5 - - - - 0.00000000000000000000000000000000001301 136.0
LZS2_k127_3442880_0 PFAM Iron-containing alcohol dehydrogenase K18602 - - 2.597e-200 624.0
LZS2_k127_3442880_1 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 432.0
LZS2_k127_3489186_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 5.978e-195 611.0
LZS2_k127_3489186_1 - - - - 0.0000000000000000000000000000000000000000000000001601 177.0
LZS2_k127_3489186_2 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000000000000001052 162.0
LZS2_k127_3489186_3 Peptidase family M50 - - - 0.0000003075 52.0
LZS2_k127_3526754_0 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 382.0
LZS2_k127_3526754_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001281 228.0
LZS2_k127_3526754_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000000000000003618 171.0
LZS2_k127_3526754_3 - - - - 0.0000000000000000000000000000000001368 135.0
LZS2_k127_3526754_4 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000006027 85.0
LZS2_k127_3561326_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.102e-289 892.0
LZS2_k127_3631737_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.898e-273 842.0
LZS2_k127_3631737_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 571.0
LZS2_k127_3631737_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 434.0
LZS2_k127_3631737_3 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000000000000000000000001481 137.0
LZS2_k127_3631737_4 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000000000000000000000007439 127.0
LZS2_k127_3634136_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 370.0
LZS2_k127_3634136_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009266 337.0
LZS2_k127_3634136_2 Zn-finger in ubiquitin-hydrolases and other protein - - - 0.00000000000000000000000000000000000000000000000003201 178.0
LZS2_k127_3634136_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000002136 176.0
LZS2_k127_36373_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 7.174e-203 637.0
LZS2_k127_36373_1 Ribosome biogenesis protein, C-terminal K09140 - - 0.0000000000000000000000000000000000000000000000000000000000000000529 222.0
LZS2_k127_3640301_0 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 5.969e-196 613.0
LZS2_k127_3640301_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 364.0
LZS2_k127_3640301_2 - - - - 0.00000000000000000000000000000000000000002789 152.0
LZS2_k127_3654550_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0 1172.0
LZS2_k127_3654550_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 7.71e-316 971.0
LZS2_k127_3654550_10 PFAM ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 321.0
LZS2_k127_3654550_11 PUA domain K07575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 297.0
LZS2_k127_3654550_12 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 296.0
LZS2_k127_3654550_13 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 281.0
LZS2_k127_3654550_14 DoxX family K15977,K16937 - 1.8.5.2 0.000000000000000000000000000000000000000000000000000000000000000007414 226.0
LZS2_k127_3654550_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000007477 213.0
LZS2_k127_3654550_16 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000000002209 212.0
LZS2_k127_3654550_17 - - - - 0.00000000000000000000000000000000000000000000000000000000009599 205.0
LZS2_k127_3654550_18 - - - - 0.0000000000000000000000000000000000000000000000000003858 190.0
LZS2_k127_3654550_19 - - - - 0.000000000000000000000000000000000000000000000000003876 182.0
LZS2_k127_3654550_2 Peptidase dimerisation domain - - - 5.742e-269 830.0
LZS2_k127_3654550_20 COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - 0.00000000000000000000000000000000000000000004866 162.0
LZS2_k127_3654550_21 Cytochrome C oxidase, subunit II K00376,K02275 - 1.7.2.4,1.9.3.1 0.0000000000000000000000000000000000005904 147.0
LZS2_k127_3654550_22 transcriptional regulators - - - 0.00000000000000000000000000000000001312 139.0
LZS2_k127_3654550_23 - - - - 0.0000000000000000000000000001181 117.0
LZS2_k127_3654550_3 homoserine dehydrogenase K00003 - 1.1.1.3 1.576e-203 636.0
LZS2_k127_3654550_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 9.516e-203 633.0
LZS2_k127_3654550_5 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 516.0
LZS2_k127_3654550_6 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 516.0
LZS2_k127_3654550_7 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 482.0
LZS2_k127_3654550_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 453.0
LZS2_k127_3654550_9 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 376.0
LZS2_k127_3662204_0 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 343.0
LZS2_k127_3662204_1 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001067 257.0
LZS2_k127_3662204_2 - - - - 0.0000000000000000000000000000000000007283 143.0
LZS2_k127_3684307_0 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 414.0
LZS2_k127_3684307_1 PFAM 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 344.0
LZS2_k127_3684307_2 PFAM 4Fe-4S dicluster domain - - - 0.00000000000000008324 79.0
LZS2_k127_3684307_3 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000008236 63.0
LZS2_k127_3684445_0 Sodium hydrogen exchanger K11105 - - 1.227e-232 724.0
LZS2_k127_3684445_1 Inositol monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 477.0
LZS2_k127_3684445_2 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 448.0
LZS2_k127_3684445_3 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 347.0
LZS2_k127_3684445_4 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.0000000000000000000000000000000000001164 147.0
LZS2_k127_3684445_5 - - - - 0.00000000000000000000000000000006709 125.0
LZS2_k127_3684445_6 - - - - 0.000000000000000000000000000003926 120.0
LZS2_k127_3717150_0 COG1914 Mn2 and Fe2 transporters of the NRAMP family - - - 3.84e-223 698.0
LZS2_k127_3717150_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 338.0
LZS2_k127_3717150_11 Chlorophyllase K01061 - 3.1.1.45 0.00000000007678 62.0
LZS2_k127_3717150_12 - - - - 0.00000000467 66.0
LZS2_k127_3717150_2 PFAM Ferritin, Dps family protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006147 281.0
LZS2_k127_3717150_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000009913 235.0
LZS2_k127_3717150_4 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000001149 214.0
LZS2_k127_3717150_5 - - - - 0.0000000000000000000000000000000000000000000000000000001901 194.0
LZS2_k127_3717150_6 - - - - 0.00000000000000000000000000000000000000000000000000002287 188.0
LZS2_k127_3717150_8 - - - - 0.0000000000000000000000000000004697 121.0
LZS2_k127_3717150_9 - - - - 0.000000000000000000000003027 103.0
LZS2_k127_3821862_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001348 252.0
LZS2_k127_3821862_1 - - - - 0.000000000000000000000000000003425 126.0
LZS2_k127_3821862_2 - - - - 0.000000000000000004429 89.0
LZS2_k127_3821862_3 Lrp/AsnC ligand binding domain - - - 0.0000003775 54.0
LZS2_k127_3894553_0 DEAD/H associated K03724 - - 7.094e-263 812.0
LZS2_k127_3894553_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 434.0
LZS2_k127_3933136_0 Phosphate uptake regulator - - - 1.115e-200 627.0
LZS2_k127_3933136_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 2.015e-198 622.0
LZS2_k127_3933136_2 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003768 342.0
LZS2_k127_3933136_3 Patch-forming domain C2 of tRNA-guanine transglycosylase K07398 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004948 261.0
LZS2_k127_3933136_4 PFAM Aldehyde dehydrogenase K00135,K18601 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000001087 204.0
LZS2_k127_3933136_5 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000000000000000000000000000000000000000005305 199.0
LZS2_k127_3933136_6 - - - - 0.0000000000000000000000000000000000000000000000000405 180.0
LZS2_k127_3933136_7 H subunit K02107 - - 0.000000000000000000000000000000000000000000000001001 176.0
LZS2_k127_3933136_8 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.0000000000000000000000000000000000000003801 155.0
LZS2_k127_4032045_0 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 347.0
LZS2_k127_4032045_1 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001068 297.0
LZS2_k127_4032045_2 FeS assembly protein SufB K09014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002106 256.0
LZS2_k127_4087997_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0 1054.0
LZS2_k127_4087997_1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 404.0
LZS2_k127_4087997_2 Protein of unknown function (DUF726) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 397.0
LZS2_k127_4115860_0 - - - - 0.00000000000000000000000000000000000000000001295 164.0
LZS2_k127_4115860_1 - - - - 0.00000000000000000000000000000000000011 142.0
LZS2_k127_4115860_2 - - - - 0.0000000000000000006558 88.0
LZS2_k127_4223114_0 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 443.0
LZS2_k127_4223114_1 transcription factor (CBF NF-Y) - - - 0.000000000000000000000000000000000001352 139.0
LZS2_k127_4223114_2 ribosomal protein K02962 - - 0.0000000000000000000000000000001885 126.0
LZS2_k127_4223114_3 Kinase binding protein CGI-121 - - - 0.000000000000000000000517 96.0
LZS2_k127_427924_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 437.0
LZS2_k127_427924_1 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 416.0
LZS2_k127_427924_10 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000008915 141.0
LZS2_k127_427924_11 COG1525 Micrococcal nuclease (thermonuclease) homologs K01174 - 3.1.31.1 0.0000000000000000008825 94.0
LZS2_k127_427924_2 PFAM GCN5-related N-acetyltransferase K03789 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 368.0
LZS2_k127_427924_3 Large family of predicted nucleotide-binding domains K06865 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 334.0
LZS2_k127_427924_4 Uncharacterized ACR, COG1430 K09005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 287.0
LZS2_k127_427924_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008962 247.0
LZS2_k127_427924_6 COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000297 241.0
LZS2_k127_427924_7 iron dependent repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000001437 229.0
LZS2_k127_427924_8 - - - - 0.00000000000000000000000000000000000000000000000000000000002067 208.0
LZS2_k127_427924_9 domain, Protein K03455 - - 0.00000000000000000000000000000000000000000000000000000004629 217.0
LZS2_k127_433448_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 1.009e-300 924.0
LZS2_k127_433448_1 Glucose sorbosone - - - 0.00000000000000000000000000000000000000000002284 164.0
LZS2_k127_433448_4 self proteolysis - - - 0.000000000000000441 82.0
LZS2_k127_4337059_0 AAA domain K03546 - - 6.046e-275 856.0
LZS2_k127_4337059_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 353.0
LZS2_k127_442983_0 copper ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 606.0
LZS2_k127_442983_1 Adenylate guanylate cyclase with integral membrane sensor - - - 0.0000000000000000000000000151 111.0
LZS2_k127_442983_2 4Fe-4S binding domain - - - 0.0000000000000000000005567 94.0
LZS2_k127_44707_0 Nitroreductase K19286 - 1.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 546.0
LZS2_k127_44707_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003595 471.0
LZS2_k127_44707_2 - - - - 0.000000000000000000000000000000000000000000000000001299 186.0
LZS2_k127_44707_3 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000228 134.0
LZS2_k127_44707_4 - - - - 0.0000000000000001064 80.0
LZS2_k127_4506452_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1060.0
LZS2_k127_4545431_0 DinB superfamily - - - 1.031e-262 812.0
LZS2_k127_4545431_1 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 562.0
LZS2_k127_4545431_2 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 520.0
LZS2_k127_4545431_3 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000001009 117.0
LZS2_k127_4545431_4 SMC proteins Flexible Hinge Domain K03529 - - 0.000000000000000000000000001369 111.0
LZS2_k127_4548083_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 3.687e-217 676.0
LZS2_k127_4548083_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 345.0
LZS2_k127_4548083_2 Dual specificity phosphatase, catalytic domain K14165 - 3.1.3.16,3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 327.0
LZS2_k127_4548083_3 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000004403 155.0
LZS2_k127_4548083_4 - - - - 0.0000000000000000006709 86.0
LZS2_k127_4551515_0 TIGRFAM phosphate ABC transporter K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 468.0
LZS2_k127_4551515_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 375.0
LZS2_k127_4551515_2 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001819 285.0
LZS2_k127_4551515_3 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000001638 201.0
LZS2_k127_4554597_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 343.0
LZS2_k127_4554597_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000002056 216.0
LZS2_k127_4554597_2 Domain of unknown function (DUF4149) - - - 0.000006756 54.0
LZS2_k127_455892_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1163.0
LZS2_k127_455892_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 454.0
LZS2_k127_455892_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000003859 101.0
LZS2_k127_4560175_0 conserved protein implicated in secretion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 344.0
LZS2_k127_4560175_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005814 225.0
LZS2_k127_4569184_0 Succinyl-CoA ligase like flavodoxin domain K18594 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 511.0
LZS2_k127_4569184_1 Belongs to the enoyl-CoA hydratase isomerase family K15019 - 4.2.1.116 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 486.0
LZS2_k127_4569184_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 369.0
LZS2_k127_4569184_3 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001554 245.0
LZS2_k127_4569184_4 CBS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002193 231.0
LZS2_k127_4569184_5 transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000001042 201.0
LZS2_k127_4569184_6 Iron-sulfur cluster assembly accessory protein K13628 - - 0.00000000000000000000003167 99.0
LZS2_k127_4570373_0 Radical SAM K11781 - 2.5.1.77 2.945e-245 760.0
LZS2_k127_4570373_1 Radical SAM K11780 - 2.5.1.77 2.352e-220 687.0
LZS2_k127_4570373_2 Trypsin-like serine protease with C-terminal PDZ domain - - - 1.58e-196 622.0
LZS2_k127_4570373_3 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 410.0
LZS2_k127_4570373_4 PFAM Glycosyl transferase family 2 K07011,K11936 - - 0.000000000000000000000000000000000000001292 149.0
LZS2_k127_4648869_0 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 582.0
LZS2_k127_4648869_1 Thiamine biosynthesis protein (ThiI) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 365.0
LZS2_k127_4678892_0 Formyl transferase K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 515.0
LZS2_k127_4678892_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 430.0
LZS2_k127_4678892_2 Belongs to the phosphohexose mutase family K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000001823 96.0
LZS2_k127_4695341_0 RNase L inhibitor, RLI K06174 - - 0.0 1120.0
LZS2_k127_4695341_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 554.0
LZS2_k127_4695341_2 Met-10+ like-protein K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006628 271.0
LZS2_k127_4698267_0 LOR SDH bifunctional - - - 5.166e-245 758.0
LZS2_k127_4698267_1 transcriptional - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 527.0
LZS2_k127_4698267_2 KaiC K08482 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 440.0
LZS2_k127_4698267_5 HD domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
LZS2_k127_4698267_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000188 211.0
LZS2_k127_4698267_7 - - - - 0.00000000000000000000000000000000000000000000000000003907 188.0
LZS2_k127_4698267_8 - - - - 0.00000000000000000000000008007 108.0
LZS2_k127_4698619_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 3.344e-216 672.0
LZS2_k127_4698619_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 576.0
LZS2_k127_4698619_2 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 299.0
LZS2_k127_4698619_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009165 248.0
LZS2_k127_4698619_4 - - - - 0.00000000000000000000000000000000000000000000000238 175.0
LZS2_k127_4698619_5 elongation factor Tu - - - 0.000000000000000000000000000001143 121.0
LZS2_k127_4700022_0 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 503.0
LZS2_k127_4700022_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000011 241.0
LZS2_k127_4700022_2 Bacterial regulatory protein, arsR family - - - 0.000000000000000000000000000000000000000000000000000001669 193.0
LZS2_k127_4700022_3 - - - - 0.00000000000000000000000000000000000000000001845 162.0
LZS2_k127_4700022_4 Succinyl-CoA ligase like flavodoxin domain K18593 - - 0.00000000000004815 72.0
LZS2_k127_4702137_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 569.0
LZS2_k127_4702137_1 HD domain K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 291.0
LZS2_k127_4702137_2 - - - - 0.0000000000000000000000000000000000000000005867 161.0
LZS2_k127_4702983_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 430.0
LZS2_k127_4702983_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 294.0
LZS2_k127_4702983_2 Carbon-nitrogen hydrolase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000002726 216.0
LZS2_k127_4736570_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.551e-248 768.0
LZS2_k127_4736570_1 TIGRFAM ABC transporter, substrate-binding protein, aliphatic sulfonates family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 531.0
LZS2_k127_4736570_2 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 486.0
LZS2_k127_4736570_3 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 457.0
LZS2_k127_4736570_4 Major facilitator superfamily K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003532 266.0
LZS2_k127_4736570_5 Lysine biosynthesis K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000202 204.0
LZS2_k127_4736570_6 lysine biosynthesis protein LysW K05826 - - 0.00000000000000000000000000001051 118.0
LZS2_k127_4737382_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 3.562e-235 729.0
LZS2_k127_4737382_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 377.0
LZS2_k127_4737382_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000001477 123.0
LZS2_k127_4743663_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 1.08e-220 685.0
LZS2_k127_4743663_1 ATPase family associated with various cellular activities (AAA) K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003469 271.0
LZS2_k127_47845_0 transcriptional regulators K03711,K09825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003739 254.0
LZS2_k127_47845_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005809 249.0
LZS2_k127_47845_3 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.000000000433 63.0
LZS2_k127_47845_4 - - - - 0.000000002715 58.0
LZS2_k127_4794636_0 synthetase (class II) K01880 - 6.1.1.14 8.682e-299 918.0
LZS2_k127_4794636_1 Uncharacterised protein family (UPF0182) K09118 - - 1.645e-240 747.0
LZS2_k127_4794636_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 7.875e-221 687.0
LZS2_k127_4794636_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 4.367e-209 651.0
LZS2_k127_4794636_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 540.0
LZS2_k127_4794636_5 domain, Protein K01181 - 3.2.1.8 0.0000000002935 74.0
LZS2_k127_4823443_0 Major Intrinsic Protein K06188,K09866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 432.0
LZS2_k127_4823443_1 RNA methylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 381.0
LZS2_k127_4823443_2 - - - - 0.00000000000000000000000000000000002075 144.0
LZS2_k127_4824111_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 2.695e-209 656.0
LZS2_k127_4824111_1 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 419.0
LZS2_k127_4824111_2 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 398.0
LZS2_k127_4824111_3 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 401.0
LZS2_k127_4824111_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 294.0
LZS2_k127_4824111_5 - - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
LZS2_k127_4824111_6 Belongs to the peptidase M24B family K01262,K01271 - 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000965 156.0
LZS2_k127_4853785_0 amino acid K03294 - - 1.099e-219 687.0
LZS2_k127_4853785_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002849 311.0
LZS2_k127_4853785_11 - - - - 0.0000000000000003562 80.0
LZS2_k127_4853785_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001084 243.0
LZS2_k127_4853785_3 CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000008403 236.0
LZS2_k127_4853785_4 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000006369 225.0
LZS2_k127_4853785_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000001607 214.0
LZS2_k127_4853785_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.000000000000000000000000000000000000000000000000000000002603 202.0
LZS2_k127_4853785_7 CBS domain K07182 - - 0.0000000000000000000000000000000000000000000000000001009 186.0
LZS2_k127_4853785_8 - - - - 0.000000000000000000000000000000000000000000000000002471 183.0
LZS2_k127_4853785_9 COG0784 FOG CheY-like receiver K03413 - - 0.00000000000000000000000000000000000000001001 156.0
LZS2_k127_4861269_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 2062.0
LZS2_k127_4861269_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 2.046e-306 940.0
LZS2_k127_4884957_0 Belongs to the complex I 49 kDa subunit family K00333 - 1.6.5.3 1.217e-250 773.0
LZS2_k127_4884957_1 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 567.0
LZS2_k127_4884957_2 NADH ubiquinone oxidoreductase 27 kD subunit K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 354.0
LZS2_k127_4884957_3 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000002459 217.0
LZS2_k127_4907355_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 580.0
LZS2_k127_4907355_1 component I K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 464.0
LZS2_k127_4915966_0 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007351 430.0
LZS2_k127_4915966_1 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 424.0
LZS2_k127_4915966_2 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 286.0
LZS2_k127_4915966_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 280.0
LZS2_k127_4915966_4 Located at the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000000000000000000000000001502 227.0
LZS2_k127_4915966_5 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000000000000000000000001612 212.0
LZS2_k127_4915966_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000002038 167.0
LZS2_k127_4915966_7 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000000000000000000000000000000000005896 154.0
LZS2_k127_4915966_8 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000000000000000000002665 115.0
LZS2_k127_4915966_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000001182 109.0
LZS2_k127_491711_0 ATP synthase (C/AC39) subunit K02119 - - 4.863e-204 637.0
LZS2_k127_491711_1 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000000000000000000000000009945 231.0
LZS2_k127_491711_2 - - - - 0.000000000000000000000000000000007505 128.0
LZS2_k127_4919817_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 2.738e-287 884.0
LZS2_k127_4919817_1 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 312.0
LZS2_k127_4936204_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1700.0
LZS2_k127_4975367_0 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 553.0
LZS2_k127_4975367_1 inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 520.0
LZS2_k127_4975367_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003728 277.0
LZS2_k127_4975367_3 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000167 251.0
LZS2_k127_4975367_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000005221 214.0
LZS2_k127_4975367_5 - - - - 0.00000000000000000000000000000000000000000000000000000003886 197.0
LZS2_k127_4975367_6 - - - - 0.0000000000000000000000000000000000000000000000000001898 186.0
LZS2_k127_4975367_7 - - - - 0.000000000000000000000000000000000000000000000000175 179.0
LZS2_k127_4994801_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K18604 - 2.1.3.15,6.4.1.2,6.4.1.3 0.0 1030.0
LZS2_k127_4994801_1 Carbamoyl-phosphate synthase L chain K18603 - 6.4.1.2,6.4.1.3 2.05e-303 932.0
LZS2_k127_4994801_2 Biotin-requiring enzyme K18605 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 297.0
LZS2_k127_4994801_3 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 290.0
LZS2_k127_4994801_4 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000006828 214.0
LZS2_k127_4994801_5 - - - - 0.000000000000000000000000000000000000000000000000000000009098 198.0
LZS2_k127_5022627_0 TPR repeat - - - 7.89e-217 675.0
LZS2_k127_5022627_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 471.0
LZS2_k127_5028026_0 - - - - 3.424e-268 833.0
LZS2_k127_5028026_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 467.0
LZS2_k127_5028026_2 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 351.0
LZS2_k127_5028026_3 ribosomal protein K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 325.0
LZS2_k127_5028026_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000003435 117.0
LZS2_k127_5028026_5 - - - - 0.00000000000000000000006356 100.0
LZS2_k127_5028026_6 - - - - 0.0000000000000000000007635 94.0
LZS2_k127_5028026_7 - - - - 0.0000000000000005364 80.0
LZS2_k127_5028026_8 transcriptional regulators - - - 0.0009645 43.0
LZS2_k127_5052811_0 Mechanosensitive ion channel K05802 - - 2.747e-292 906.0
LZS2_k127_5052811_1 TIGRFAM lysine 2,3-aminomutase YodO family protein - - - 4.276e-289 888.0
LZS2_k127_5052811_10 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000000000000001053 223.0
LZS2_k127_5052811_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 2.028e-252 782.0
LZS2_k127_5052811_3 DnaJ molecular chaperone homology domain - - - 1.238e-209 655.0
LZS2_k127_5052811_4 RNA methylase K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 577.0
LZS2_k127_5052811_5 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 545.0
LZS2_k127_5052811_6 Ribose-phosphate pyrophosphokinase K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 494.0
LZS2_k127_5052811_7 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 433.0
LZS2_k127_5052811_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 314.0
LZS2_k127_5052811_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 286.0
LZS2_k127_5168270_0 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 374.0
LZS2_k127_5168270_1 Transcriptional regulator K07108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001304 273.0
LZS2_k127_5168270_2 Alba K03622 - - 0.00000000000000000000000000000000000000001277 154.0
LZS2_k127_5184748_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0 1124.0
LZS2_k127_5184748_1 Transglutaminase-like superfamily - - - 1.682e-278 863.0
LZS2_k127_5184748_2 small GTP-binding protein K06944 - - 2.368e-219 682.0
LZS2_k127_5184748_3 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 505.0
LZS2_k127_5184748_4 Phosphoglycolate phosphatase K22223 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 395.0
LZS2_k127_5184748_5 Fe-S-cluster oxidoreductase K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 288.0
LZS2_k127_5241984_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 3.37e-273 841.0
LZS2_k127_5241984_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001263 308.0
LZS2_k127_5241984_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000000001437 209.0
LZS2_k127_5241984_3 Zinc finger, C2H2 type - - - 0.0000000000000000000000000000002682 123.0
LZS2_k127_5241984_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00000000000000000000000000472 111.0
LZS2_k127_5241984_5 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000009172 103.0
LZS2_k127_5257175_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 6.719e-205 638.0
LZS2_k127_5257175_1 Pyruvate ferredoxin flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000001362 269.0
LZS2_k127_5257175_2 - - - - 0.00000002891 54.0
LZS2_k127_5320208_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 1.306e-248 769.0
LZS2_k127_5320208_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 589.0
LZS2_k127_5320208_2 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008829 349.0
LZS2_k127_5320208_3 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000001043 261.0
LZS2_k127_5320208_4 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.00000000000000000000000000000000000000000000000000000009184 198.0
LZS2_k127_5320208_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000001522 198.0
LZS2_k127_5325902_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.0 1156.0
LZS2_k127_5325902_1 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000001226 194.0
LZS2_k127_5325902_2 low-complexity proteins - - - 0.000000000004374 66.0
LZS2_k127_5329643_0 diphthine synthase K20215 - 2.1.1.98 3.985e-199 624.0
LZS2_k127_5329643_1 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003269 452.0
LZS2_k127_5329643_2 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.00000000000000000000000000000000000000000000000000000000000003606 216.0
LZS2_k127_5356111_0 ABC1 family - - - 2.589e-291 899.0
LZS2_k127_5356111_1 CBS domain K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009517 588.0
LZS2_k127_5356111_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000003264 227.0
LZS2_k127_5356111_3 Belongs to the small heat shock protein (HSP20) family - - - 0.00000000000000000000000000000000000000000000000000000000000000001942 224.0
LZS2_k127_5356111_4 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000000000000000000000000000000003409 213.0
LZS2_k127_5356111_5 - - - - 0.0000000000000000000000000000000000000001143 153.0
LZS2_k127_5491091_0 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 496.0
LZS2_k127_5491091_1 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 473.0
LZS2_k127_5491091_2 Ribosomal L37ae protein family K02921 - - 0.0000000000000000000000000000000000002333 141.0
LZS2_k127_5491091_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 - - 0.000000000271 60.0
LZS2_k127_5506027_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 374.0
LZS2_k127_5506027_1 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 306.0
LZS2_k127_5607545_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 328.0
LZS2_k127_5607545_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000504 256.0
LZS2_k127_5607545_2 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000003373 178.0
LZS2_k127_5607545_3 Transcriptional regulator, AbiEi antitoxin - - - 0.000000000000000000000000000000000000002313 154.0
LZS2_k127_5607545_5 Transcriptional regulator - - - 0.00000000000000000000000000001721 121.0
LZS2_k127_5607545_6 cheY-homologous receiver domain - - - 0.0000000000000000000000007214 108.0
LZS2_k127_5607545_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000003869 78.0
LZS2_k127_5608182_0 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 436.0
LZS2_k127_5608182_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 401.0
LZS2_k127_5608182_2 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005286 270.0
LZS2_k127_5619137_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0 1309.0
LZS2_k127_5619137_1 Predicted membrane protein (DUF2070) K08979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 521.0
LZS2_k127_5619137_2 - - - - 0.0000000000000001015 89.0
LZS2_k127_5624269_0 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 4.386e-218 678.0
LZS2_k127_5624269_1 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 518.0
LZS2_k127_5624269_2 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 479.0
LZS2_k127_5624269_3 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 477.0
LZS2_k127_5624269_4 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 344.0
LZS2_k127_5624269_5 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 326.0
LZS2_k127_5624269_6 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000000000000000000000000000001736 183.0
LZS2_k127_5624269_7 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000006286 108.0
LZS2_k127_5624269_8 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000001443 63.0
LZS2_k127_5629156_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005063 373.0
LZS2_k127_5629156_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000606 223.0
LZS2_k127_5629156_2 transport protein CorA K03284 - - 0.0000000002351 61.0
LZS2_k127_5641699_0 Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 506.0
LZS2_k127_5641699_1 Nucleotidyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 381.0
LZS2_k127_5641699_2 - - - - 0.000000000000000000000001643 102.0
LZS2_k127_5658475_0 Radical SAM K18285 - 2.5.1.120 4.284e-225 699.0
LZS2_k127_5658475_1 DnaJ molecular chaperone homology domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005276 273.0
LZS2_k127_5658475_2 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008191 259.0
LZS2_k127_5658475_3 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007317 254.0
LZS2_k127_5658475_4 - - - - 0.00000000000000000000000000000000000000000000000000001178 191.0
LZS2_k127_5658475_5 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000000000000004863 179.0
LZS2_k127_5658475_6 - - - - 0.000000000000000000000000000000000000001554 148.0
LZS2_k127_5658475_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000209 132.0
LZS2_k127_5658475_8 - - - - 0.00000000000000000000000000001009 117.0
LZS2_k127_5658475_9 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000009496 72.0
LZS2_k127_5662450_0 Hydroxymethylglutaryl-coenzyme A synthase N terminal K01641 - 2.3.3.10 1.977e-292 899.0
LZS2_k127_5662450_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 2.181e-240 747.0
LZS2_k127_5662450_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 375.0
LZS2_k127_5662450_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006091 278.0
LZS2_k127_5662450_4 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000325 235.0
LZS2_k127_5662450_5 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000005126 215.0
LZS2_k127_5662450_6 - - - - 0.0000000000000000005861 93.0
LZS2_k127_5672889_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.766e-244 758.0
LZS2_k127_5672889_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009579 383.0
LZS2_k127_5672889_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000164 248.0
LZS2_k127_5672889_3 - - - - 0.0000000000000000000000006103 106.0
LZS2_k127_568372_0 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 480.0
LZS2_k127_568372_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 362.0
LZS2_k127_568372_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000001726 78.0
LZS2_k127_5685032_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 602.0
LZS2_k127_5685032_1 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 482.0
LZS2_k127_5685032_2 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 454.0
LZS2_k127_5685032_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 315.0
LZS2_k127_5688261_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0 1064.0
LZS2_k127_5688261_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 392.0
LZS2_k127_5688261_2 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 343.0
LZS2_k127_5688261_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005854 343.0
LZS2_k127_5688261_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000002171 225.0
LZS2_k127_5688261_5 - - - - 0.000000000000000000000000000000000000000007121 154.0
LZS2_k127_5695870_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1296.0
LZS2_k127_5695870_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5.187e-289 899.0
LZS2_k127_5708919_0 4Fe-4S binding domain K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 348.0
LZS2_k127_5708919_1 NADH dehydrogenase K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 311.0
LZS2_k127_5708919_2 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000008603 61.0
LZS2_k127_5721794_0 Pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 388.0
LZS2_k127_5721794_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003663 239.0
LZS2_k127_5721794_2 - - - - 0.000000000000000000000000000001124 123.0
LZS2_k127_5731799_0 divalent heavy-metal cations transporter - - - 3.746e-222 692.0
LZS2_k127_5731799_1 cation diffusion facilitator family transporter - - - 9.763e-204 637.0
LZS2_k127_5731799_2 PFAM Multicopper oxidase - - - 0.00000004781 54.0
LZS2_k127_5740574_0 MGS-like domain K01955 - 6.3.5.5 0.0 1554.0
LZS2_k127_5740574_1 carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 1.443e-217 678.0
LZS2_k127_5740574_2 AAA domain (Cdc48 subfamily) - - - 8.825e-199 620.0
LZS2_k127_5760742_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.0 1014.0
LZS2_k127_5760742_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 6.378e-194 607.0
LZS2_k127_5760742_2 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 551.0
LZS2_k127_5760742_3 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 504.0
LZS2_k127_5760742_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 332.0
LZS2_k127_5760742_5 ribosomal protein K02976 - - 0.0000000000000000000000000000000000000000000000000002803 185.0
LZS2_k127_5760742_6 - - - - 0.0000000000000000000006317 96.0
LZS2_k127_5760742_7 transcriptional regulators - - - 0.00000000000000002835 89.0
LZS2_k127_5760742_8 - - - - 0.0000000000000007306 80.0
LZS2_k127_5760742_9 transcriptional regulators - - - 0.0000002472 59.0
LZS2_k127_5763817_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0 1289.0
LZS2_k127_5763817_1 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 - 1.6.99.3 8.598e-279 859.0
LZS2_k127_5763817_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 583.0
LZS2_k127_5763817_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 383.0
LZS2_k127_5763817_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 287.0
LZS2_k127_5763817_5 carbon-nitrogen ligase activity, with glutamine as amido-N-donor - - - 0.00000000000000000000000000000000000000000000000002032 182.0
LZS2_k127_5763817_6 - - - - 0.000000000000000000000000000000000000008061 145.0
LZS2_k127_5763817_7 small metal-binding protein - - - 0.00000000000000000003846 89.0
LZS2_k127_5771997_0 AhpC/TSA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005416 370.0
LZS2_k127_5771997_1 conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009023 349.0
LZS2_k127_5771997_2 - - - - 0.000000000000000000000000000006214 120.0
LZS2_k127_5772018_0 PFAM Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 1.344e-203 637.0
LZS2_k127_5772018_1 factor TFIIB K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009995 445.0
LZS2_k127_5772018_10 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000000000000000000001108 217.0
LZS2_k127_5772018_11 SRP19 protein K03105 - - 0.0000000000000000000000000000000000000000000000004238 176.0
LZS2_k127_5772018_12 RNA-binding protein involved in rRNA processing K07569 - - 0.0000000000000000000000000000000000000303 144.0
LZS2_k127_5772018_13 Cold shock protein domain K03704 - - 0.000000000000000000000000000000009343 128.0
LZS2_k127_5772018_14 helix_turn_helix ASNC type K03719 - - 0.0000000151 62.0
LZS2_k127_5772018_2 response regulator, receiver K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 407.0
LZS2_k127_5772018_3 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000741 400.0
LZS2_k127_5772018_4 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 372.0
LZS2_k127_5772018_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 354.0
LZS2_k127_5772018_6 segregation and condensation protein K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 343.0
LZS2_k127_5772018_7 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 322.0
LZS2_k127_5772018_8 Functions by promoting the formation of the first peptide bond K03263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000106 272.0
LZS2_k127_5772018_9 Ribosomal protein S8e K02995 - - 0.000000000000000000000000000000000000000000000000000000000000000002165 228.0
LZS2_k127_5824598_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 1.359e-318 976.0
LZS2_k127_5824598_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 462.0
LZS2_k127_5824598_2 Transposase, is605 orfb family K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000515 385.0
LZS2_k127_5824598_3 - - - - 0.000000000000000000000000000000000000000000000000000000004379 199.0
LZS2_k127_5824598_4 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000000000000000000000000001289 168.0
LZS2_k127_5828235_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 563.0
LZS2_k127_5828235_1 - - - - 0.000000000000000000000000227 106.0
LZS2_k127_5835765_0 N-methylhydantoinase A acetone carboxylase, beta subunit - - - 6.835e-247 770.0
LZS2_k127_5837486_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 556.0
LZS2_k127_5837486_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 491.0
LZS2_k127_5837486_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 432.0
LZS2_k127_5837486_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000002749 135.0
LZS2_k127_5838541_0 UbiD family decarboxylase - - - 1.272e-262 811.0
LZS2_k127_5838541_1 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 287.0
LZS2_k127_5838541_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001844 248.0
LZS2_k127_5838541_3 - - - - 0.0000000000000000000000000000000000000000000002259 169.0
LZS2_k127_5838541_4 - - - - 0.00000000000000000000000007909 110.0
LZS2_k127_5844725_0 MGS-like domain K01955 - 6.3.5.5 0.0 1529.0
LZS2_k127_5844725_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004901 271.0
LZS2_k127_5844725_2 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000003006 111.0
LZS2_k127_5873072_0 - - - - 0.0000000000000000000000000000000000000000000000322 170.0
LZS2_k127_5873205_0 Kinase binding protein CGI-121 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 395.0
LZS2_k127_5873205_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 377.0
LZS2_k127_5873205_2 Sua5 YciO YrdC YwlC family K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 285.0
LZS2_k127_5873205_3 THUMP domain K06963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003368 278.0
LZS2_k127_5873205_4 Bacterial Fe(2+) trafficking - - - 0.00000000000000000000000000000000000000000000000000002285 188.0
LZS2_k127_5873205_5 Winged helix-turn-helix - - - 0.0000000000000000000000000000000000000000000000006404 175.0
LZS2_k127_5873205_6 - - - - 0.00000000000000000000000000000000003189 134.0
LZS2_k127_5873205_7 ribosomal protein K02962 - - 0.0000000000000000000000000000001437 126.0
LZS2_k127_5886677_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1210.0
LZS2_k127_5905895_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 471.0
LZS2_k127_5905895_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 456.0
LZS2_k127_5905895_2 - - - - 0.000000000000000000000000000000000000000000000000000001834 193.0
LZS2_k127_5905895_3 - - - - 0.0000000000000000000000001832 107.0
LZS2_k127_5905895_4 Belongs to the small heat shock protein (HSP20) family - - - 0.0000000000000009478 77.0
LZS2_k127_5905987_2 Major facilitator superfamily - - - 0.000000000000000000000008974 115.0
LZS2_k127_5905987_3 Predicted membrane protein (DUF2061) - - - 0.0008684 44.0
LZS2_k127_5925410_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 411.0
LZS2_k127_5925410_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 279.0
LZS2_k127_5925410_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000006705 57.0
LZS2_k127_5927851_0 Cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 460.0
LZS2_k127_5927851_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 293.0
LZS2_k127_5927851_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001633 258.0
LZS2_k127_5927851_3 - - - - 0.00000000000000000000000000000000000001763 144.0
LZS2_k127_5927851_4 - - - - 0.000000000000000000000000000000002271 129.0
LZS2_k127_5944834_0 Major Intrinsic Protein K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 404.0
LZS2_k127_5944834_1 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 299.0
LZS2_k127_5944834_2 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004536 271.0
LZS2_k127_5944834_3 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000486 204.0
LZS2_k127_5944834_4 regulatory protein, arsR K03892,K21903 - - 0.0000000000000000000000000000000000000000000000000000009463 192.0
LZS2_k127_5944834_5 Nitrogen regulatory protein P-II - - - 0.000000000000000000000000000000000000000000000004731 175.0
LZS2_k127_5957762_0 Histone acetyltransferase K07739 - 2.3.1.48 0.0 1006.0
LZS2_k127_5957762_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 1.1e-320 985.0
LZS2_k127_5957762_2 Sodium hydrogen exchanger - - - 5.137e-221 690.0
LZS2_k127_5957762_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 4.559e-203 636.0
LZS2_k127_5957762_4 modulator of DNA gyrase K03592 - - 2.164e-195 614.0
LZS2_k127_5957762_5 Sodium/calcium exchanger protein K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 499.0
LZS2_k127_5957762_6 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 444.0
LZS2_k127_5957762_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000468 211.0
LZS2_k127_5976438_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 333.0
LZS2_k127_5976438_1 - - - - 0.0000000000000000000000000000002089 123.0
LZS2_k127_5976438_2 - - - - 0.000000000000000000000001232 115.0
LZS2_k127_5976438_3 membrane-associated protein domain - - - 0.0000000000000000002443 87.0
LZS2_k127_5995619_0 ATP-grasp domain K01903 - 6.2.1.5 1.6e-219 683.0
LZS2_k127_5995619_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 572.0
LZS2_k127_5995619_2 Ferritin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 395.0
LZS2_k127_5995619_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000001047 246.0
LZS2_k127_5995619_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000002816 212.0
LZS2_k127_5995619_5 - - - - 0.00000000000000000000000000000000001433 136.0
LZS2_k127_5995619_6 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000000000000000001852 109.0
LZS2_k127_5995619_7 - - - - 0.00000000000000002285 82.0
LZS2_k127_5997100_0 Domain of unknown function (DUF373) K08975 - - 3.372e-209 655.0
LZS2_k127_5997100_1 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000001636 260.0
LZS2_k127_5997100_2 - - - - 0.000000000000000000000000000000003427 130.0
LZS2_k127_6017077_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 - 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 418.0
LZS2_k127_6017077_1 riboflavin synthase, alpha K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 364.0
LZS2_k127_6017077_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000000008199 238.0
LZS2_k127_6017077_3 TPR repeat K07126 - - 0.00000000000000008324 79.0
LZS2_k127_6019183_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 586.0
LZS2_k127_6019183_1 - - - - 0.000000000000000000000000000000000000000004713 156.0
LZS2_k127_6019183_2 - - - - 0.00000000000000000000000000000000000001982 143.0
LZS2_k127_6019183_3 - - - - 0.00000000000000000000000000000000000009655 141.0
LZS2_k127_6019183_4 Sodium hydrogen exchanger K11105 - - 0.0000000000000000000000000000000006291 132.0
LZS2_k127_6022676_0 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 456.0
LZS2_k127_6022676_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 392.0
LZS2_k127_6022676_2 Protein of unknown function (DUF1059) - - - 0.000000000000000000000000005035 112.0
LZS2_k127_6035043_0 HMGL-like K01649 - 2.3.3.13 1.095e-248 769.0
LZS2_k127_6035043_1 helix_turn_helix ASNC type - - - 0.000000000000000000000000000000000000000000000000000000000000000000001338 237.0
LZS2_k127_6081744_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 376.0
LZS2_k127_6081744_1 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001118 267.0
LZS2_k127_6081744_2 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000001877 156.0
LZS2_k127_6081744_3 - - - - 0.0000000000000000000000000000000003175 131.0
LZS2_k127_6092767_0 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009404 491.0
LZS2_k127_6092767_1 Transposase, is605 orfb family K07496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006731 275.0
LZS2_k127_6092888_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 458.0
LZS2_k127_6092888_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 354.0
LZS2_k127_6092888_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 300.0
LZS2_k127_6092888_3 - - - - 0.00000000000000000000000000000000000000000000000000000000004364 206.0
LZS2_k127_6136918_0 AIPR protein - - - 0.0 1099.0
LZS2_k127_6136918_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I - - - 9.726e-237 736.0
LZS2_k127_6136918_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 388.0
LZS2_k127_6136918_3 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000000000000000000000000000000000000000000000000000557 212.0
LZS2_k127_6136918_4 Winged helix-turn-helix - - - 0.000000000000000000000000000000000000000000000005175 173.0
LZS2_k127_6136918_5 - - - - 0.00000000000000000000000007792 107.0
LZS2_k127_6136918_6 - - - - 0.000000000000000000000001083 105.0
LZS2_k127_6136918_7 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000003809 107.0
LZS2_k127_6136918_8 - - - - 0.0000000000000001038 81.0
LZS2_k127_6144643_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 587.0
LZS2_k127_6144643_1 - - - - 0.0000000000000000000000000000000000000000001345 160.0
LZS2_k127_6144643_2 - - - - 0.0000000000000000000000000000000000000000002715 160.0
LZS2_k127_6165745_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 7.849e-197 616.0
LZS2_k127_6165745_1 Cysteine synthase K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 573.0
LZS2_k127_6165745_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000291 244.0
LZS2_k127_6177906_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006302 552.0
LZS2_k127_6177906_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 420.0
LZS2_k127_6177906_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 387.0
LZS2_k127_6177906_3 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 386.0
LZS2_k127_6177906_4 NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007398 325.0
LZS2_k127_6178486_0 transcriptional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 496.0
LZS2_k127_6178486_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000008879 181.0
LZS2_k127_6187779_0 ribosomal protein L3 K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 598.0
LZS2_k127_6187779_1 Ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 479.0
LZS2_k127_6187779_2 Putative RNA methyltransferase K09142 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 470.0
LZS2_k127_6187779_3 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 466.0
LZS2_k127_6187779_4 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 385.0
LZS2_k127_6187779_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 286.0
LZS2_k127_6187779_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008459 237.0
LZS2_k127_6187779_7 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.0000000000000000000000000000000000000000000004706 169.0
LZS2_k127_6189803_0 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 526.0
LZS2_k127_6189803_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000000000000000000000000000000000000001692 207.0
LZS2_k127_6192822_0 Amidohydrolase family K01464 - 3.5.2.2 6.064e-285 877.0
LZS2_k127_6192822_1 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 432.0
LZS2_k127_6192822_2 Ribose 5-phosphate isomerase K01807 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000002891 232.0
LZS2_k127_6192822_3 Integral membrane sensor signal transduction histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000001485 189.0
LZS2_k127_6192822_4 - K00960 - 2.7.7.6 0.00000000000000000003596 90.0
LZS2_k127_6194363_0 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 594.0
LZS2_k127_6194363_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 412.0
LZS2_k127_6194363_2 Acetyltransferase (GNAT) domain K00621 - 2.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 255.0
LZS2_k127_6194363_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000147 121.0
LZS2_k127_6195442_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 1.031e-219 685.0
LZS2_k127_6195442_1 Radical SAM domain protein K06941 - 2.1.1.192 2.773e-213 664.0
LZS2_k127_6195442_2 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 331.0
LZS2_k127_6195442_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000002556 234.0
LZS2_k127_6195442_4 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000004888 203.0
LZS2_k127_6195442_5 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.00000000000000000000000000000000000000000000000000000004108 196.0
LZS2_k127_6196012_0 Heat shock 70 kDa protein K04043 - - 0.0 1068.0
LZS2_k127_6196012_1 DnaJ central domain K03686 - - 2.345e-207 647.0
LZS2_k127_6196012_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 579.0
LZS2_k127_6196012_3 5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C) K05967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 301.0
LZS2_k127_6196012_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 299.0
LZS2_k127_6196012_5 Belongs to the UDP-glucose GDP-mannose dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000004209 196.0
LZS2_k127_6196012_6 - - - - 0.00000000000000000000000001138 109.0
LZS2_k127_6206451_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 548.0
LZS2_k127_6206451_1 KaiC K08482 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 339.0
LZS2_k127_6206451_2 Alkyl sulfatase dimerisation - - - 0.00000000000000000002625 103.0
LZS2_k127_6206451_3 - - - - 0.0000001679 63.0
LZS2_k127_6215983_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 4.288e-207 645.0
LZS2_k127_6215983_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002523 432.0
LZS2_k127_6215983_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003926 272.0
LZS2_k127_6215983_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000002463 87.0
LZS2_k127_6329570_0 COG2801 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000002058 141.0
LZS2_k127_6329570_1 Integrase K07482 - - 0.00000000000000000000003327 111.0
LZS2_k127_6344335_0 Belongs to the MenA family. Type 1 subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 367.0
LZS2_k127_6344335_1 histidine kinase HAMP region domain protein K03406,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000001564 194.0
LZS2_k127_6344335_2 4-hydroxybenzoate synthetase (chorismate lyase) K03181,K06984 - 2.4.2.54,4.1.3.40 0.0000000000000000000000000000000000000001848 151.0
LZS2_k127_64063_0 PFAM tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 595.0
LZS2_k127_64063_1 S-adenosyl-L-homocysteine hydrolase, NAD binding domain K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 480.0
LZS2_k127_64063_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 427.0
LZS2_k127_64063_3 Rieske-like [2Fe-2S] domain K05710 - - 0.000000000000000000000000000000000000000000000000000000000003286 208.0
LZS2_k127_643955_0 High-affinity Fe2 Pb2 permease K07243 - - 6.256e-222 706.0
LZS2_k127_643955_1 Probable cobalt transporter subunit (CbtA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 427.0
LZS2_k127_643955_2 transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000006813 207.0
LZS2_k127_643955_3 transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000006391 202.0
LZS2_k127_643955_4 - - - - 0.000000000000000000000000000006745 136.0
LZS2_k127_643955_5 Probable cobalt transporter subunit (CbtB) - - - 0.000000000000000000003947 92.0
LZS2_k127_6458575_0 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 466.0
LZS2_k127_6458575_1 Translation initiation factor K03238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008132 287.0
LZS2_k127_6458575_2 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000000000000000000000000000000000006377 235.0
LZS2_k127_6458575_3 - - - - 0.000000000000000000000000000000000000000000000002351 175.0
LZS2_k127_6458575_4 Protein of unknown function (DUF424) K09148 - - 0.000000000000000000000000000000000000001213 149.0
LZS2_k127_6458575_5 - - - - 0.0000000000000000000000003541 104.0
LZS2_k127_6481318_0 biotin-(Acetyl-CoA-carboxylase) ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 556.0
LZS2_k127_6481318_1 Zinc-dependent metalloprotease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 377.0
LZS2_k127_6481318_2 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002321 278.0
LZS2_k127_6481318_3 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000006176 237.0
LZS2_k127_6481318_4 - - - - 0.000000000000000000000000000000000000005376 146.0
LZS2_k127_6481318_5 - - - - 0.000000000000000000000000000000007297 130.0
LZS2_k127_6739906_0 - - - - 2.684e-209 655.0
LZS2_k127_6739906_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 509.0
LZS2_k127_6739906_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 404.0
LZS2_k127_6739906_3 - - - - 0.0000000000000000000000000000000000000000001325 162.0
LZS2_k127_6739906_4 - - - - 0.000000000000000000000000000000001206 130.0
LZS2_k127_6739906_5 - - - - 0.000000000000000000000001326 103.0
LZS2_k127_67638_0 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 512.0
LZS2_k127_67638_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 330.0
LZS2_k127_67638_2 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000363 241.0
LZS2_k127_67638_3 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000000000000000007575 151.0
LZS2_k127_6765007_0 PFAM aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 588.0
LZS2_k127_6765007_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 531.0
LZS2_k127_6765007_2 Belongs to the precorrin methyltransferase family K02303 - 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007213 475.0
LZS2_k127_6765007_3 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.000000000000000000000000000000000000000000000002498 174.0
LZS2_k127_6767581_0 tRNA pseudouridine synthase K06176 - 5.4.99.27 2.493e-216 676.0
LZS2_k127_6767581_1 antibiotic catabolic process K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 478.0
LZS2_k127_6767581_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 378.0
LZS2_k127_6767581_3 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000187 124.0
LZS2_k127_6767581_4 - - - - 0.0000000000000000000000001856 106.0
LZS2_k127_6783005_0 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000809 154.0
LZS2_k127_6783005_1 - - - - 0.00000000001941 66.0
LZS2_k127_6783005_2 cheY-homologous receiver domain - - - 0.000000001291 64.0
LZS2_k127_6800846_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0 1299.0
LZS2_k127_6800846_1 Belongs to the MCM family K10726 - - 9.751e-202 630.0
LZS2_k127_6827687_0 Sugar-specific transcriptional regulator TrmB - - - 1.703e-225 702.0
LZS2_k127_6827687_1 DHHA1 domain K07463 - - 1.239e-201 630.0
LZS2_k127_6827687_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002999 310.0
LZS2_k127_6827687_4 conserved protein implicated in secretion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 282.0
LZS2_k127_6827687_5 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002084 264.0
LZS2_k127_6827687_6 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000004422 194.0
LZS2_k127_6830676_0 - - - - 5.034e-275 852.0
LZS2_k127_6830676_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 5.159e-260 805.0
LZS2_k127_6830676_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001325 246.0
LZS2_k127_6830676_11 Tetrahydromethanopterin S-methyltransferase, subunit A K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000003145 243.0
LZS2_k127_6830676_12 dUTPase - - - 0.00000000000000000000000000000000000000000000000000000000000000003715 224.0
LZS2_k127_6830676_13 zinc finger - - - 0.000000000000000000000000000000694 122.0
LZS2_k127_6830676_14 - - - - 0.00000000000000000000000000000754 119.0
LZS2_k127_6830676_15 - - - - 0.0000000000000003526 80.0
LZS2_k127_6830676_16 IMP dehydrogenase activity - - - 0.00002939 48.0
LZS2_k127_6830676_2 Tyrosine--tRNA ligase K01866 - 6.1.1.1 5.071e-212 661.0
LZS2_k127_6830676_3 Belongs to the DegT DnrJ EryC1 family - - - 2.964e-202 632.0
LZS2_k127_6830676_4 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 574.0
LZS2_k127_6830676_5 Tetrapyrrole (Corrin/Porphyrin) Methylases K05934 - 2.1.1.131 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 510.0
LZS2_k127_6830676_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 363.0
LZS2_k127_6830676_7 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 311.0
LZS2_k127_6830676_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 303.0
LZS2_k127_6830676_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004843 260.0
LZS2_k127_6843081_0 Amidohydrolase family - - - 1.29e-213 667.0
LZS2_k127_6843081_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000005939 172.0
LZS2_k127_6862367_0 Methionine synthase K00548 - 2.1.1.13 0.0 1280.0
LZS2_k127_6862367_1 homocysteine S-methyltransferase K00548 - 2.1.1.13 1.665e-203 634.0
LZS2_k127_6862367_2 Major facilitator superfamily K08153 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 320.0
LZS2_k127_6874133_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 374.0
LZS2_k127_6874133_1 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 293.0
LZS2_k127_6874133_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000009236 201.0
LZS2_k127_68890_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 1.513e-200 630.0
LZS2_k127_68890_1 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 504.0
LZS2_k127_68890_2 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 464.0
LZS2_k127_68890_3 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 373.0
LZS2_k127_6896190_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 587.0
LZS2_k127_6896190_1 oxidoreductase FAD NAD(P)-binding K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 560.0
LZS2_k127_6896190_2 Nicotinamide-nucleotide adenylyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 331.0
LZS2_k127_6896190_3 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005913 273.0
LZS2_k127_6918480_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 586.0
LZS2_k127_6918480_1 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006647 283.0
LZS2_k127_6918480_2 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001528 262.0
LZS2_k127_6918480_3 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000003888 134.0
LZS2_k127_6934685_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 444.0
LZS2_k127_6934685_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 368.0
LZS2_k127_6934685_2 COG2202 FOG PAS PAC domain - - - 0.00000000000000000000000000000000000000000000000000001786 203.0
LZS2_k127_6942417_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 4.459e-225 702.0
LZS2_k127_6942417_1 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 323.0
LZS2_k127_6946685_0 major facilitator superfamily K08153,K08221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008292 537.0
LZS2_k127_6946685_1 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 497.0
LZS2_k127_6946685_2 mttA/Hcf106 family K03116 - - 0.00000000000000000000000000000000000000000000000000004465 188.0
LZS2_k127_6946685_3 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000002732 168.0
LZS2_k127_6957092_0 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1022.0
LZS2_k127_6957092_1 HELICc2 - - - 1.3e-275 856.0
LZS2_k127_6957092_10 COG0607 Rhodanese-related sulfurtransferase K03406,K21028 - 2.8.1.11 0.0000000000000000000000000000000000000000000000000004037 184.0
LZS2_k127_6957092_11 - - - - 0.0000000000000000000000000000000000000000000000003932 176.0
LZS2_k127_6957092_12 - - - - 0.00000000000000000000000000000000000000000008633 161.0
LZS2_k127_6957092_13 - - - - 0.000000000000000000000000000000000000000000301 159.0
LZS2_k127_6957092_14 - - - - 0.00000000000000000000000000000000000000006528 151.0
LZS2_k127_6957092_16 - - - - 0.00000000000000000000000000000001573 129.0
LZS2_k127_6957092_18 - - - - 0.00000000000000000000000005252 109.0
LZS2_k127_6957092_19 - - - - 0.0000000000000000000000006024 106.0
LZS2_k127_6957092_2 TIGRFAM CRISPR-associated protein Cas4 K03466,K07464,K15342,K19465 - 3.1.12.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 417.0
LZS2_k127_6957092_20 - - - - 0.000000003954 59.0
LZS2_k127_6957092_21 - - - - 0.000001995 50.0
LZS2_k127_6957092_3 Peptidase M10A and M12B matrixin and adamalysin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008456 406.0
LZS2_k127_6957092_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 345.0
LZS2_k127_6957092_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 310.0
LZS2_k127_6957092_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007548 294.0
LZS2_k127_6957092_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009484 246.0
LZS2_k127_6957092_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000005406 223.0
LZS2_k127_6957092_9 - - - - 0.000000000000000000000000000000000000000000000000000000000007468 211.0
LZS2_k127_7002303_0 Sulfite reductase K00392 - 1.8.7.1 0.0 1128.0
LZS2_k127_7002303_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 524.0
LZS2_k127_7002303_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 361.0
LZS2_k127_7002303_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000002573 66.0
LZS2_k127_70080_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 598.0
LZS2_k127_70080_1 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005273 381.0
LZS2_k127_70080_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000889 284.0
LZS2_k127_70080_3 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000001376 198.0
LZS2_k127_70080_4 CAAX protease self-immunity - - - 0.000000000000000000000006286 102.0
LZS2_k127_7016626_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 386.0
LZS2_k127_7016626_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 336.0
LZS2_k127_7016626_2 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009273 302.0
LZS2_k127_7016626_3 Universal stress protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001181 235.0
LZS2_k127_7175855_0 Histidine kinase - - - 2.099e-241 760.0
LZS2_k127_7175855_1 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 588.0
LZS2_k127_7175855_2 Large family of predicted nucleotide-binding domains K06865 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008303 489.0
LZS2_k127_7175855_3 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000084 188.0
LZS2_k127_7190044_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 1.936e-243 755.0
LZS2_k127_7190044_1 COG1522 Transcriptional regulators - - - 6.535e-212 660.0
LZS2_k127_7190044_10 - - - - 0.000000000000000000000000000000000000000000000000000000007403 199.0
LZS2_k127_7190044_11 Siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000000000002206 198.0
LZS2_k127_7190044_12 DUF167 K09131 - - 0.0000000000000000000000001178 108.0
LZS2_k127_7190044_2 Aldo/keto reductase family - - - 8.465e-210 654.0
LZS2_k127_7190044_3 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 582.0
LZS2_k127_7190044_4 FeS assembly ATPase SufC K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 488.0
LZS2_k127_7190044_5 Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 436.0
LZS2_k127_7190044_6 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 371.0
LZS2_k127_7190044_7 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 355.0
LZS2_k127_7190044_8 factor TFIIB K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000001085 237.0
LZS2_k127_7190044_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002115 220.0
LZS2_k127_7197292_0 TIGRFAM excinuclease ABC, C subunit K03703 - - 1.066e-315 971.0
LZS2_k127_7197292_1 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 550.0
LZS2_k127_7197292_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 426.0
LZS2_k127_7209244_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 499.0
LZS2_k127_7209244_1 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 419.0
LZS2_k127_7209244_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008592 285.0
LZS2_k127_7209244_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006692 256.0
LZS2_k127_7209244_4 COG2002 Regulators of stationary sporulation gene expression - - - 0.000000000000000000000000000000000000000000000000000000000000000000009133 235.0
LZS2_k127_7209244_5 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000141 229.0
LZS2_k127_7209244_6 - - - - 0.0000000000000000000000000000000000000000000000000001057 186.0
LZS2_k127_7222546_0 AAA ATPase domain - - - 3.749e-261 805.0
LZS2_k127_7222546_1 - - - - 0.0000000000000000000000000000000000005345 141.0
LZS2_k127_728948_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0 1047.0
LZS2_k127_728948_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 583.0
LZS2_k127_728948_2 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 542.0
LZS2_k127_728948_3 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000003163 108.0
LZS2_k127_7308531_0 Protein of unknown function (DUF1512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007089 603.0
LZS2_k127_7308531_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 556.0
LZS2_k127_7308531_2 PFAM Glycosyl transferase family 2 K07011,K11936 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007651 512.0
LZS2_k127_7308531_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002656 366.0
LZS2_k127_7308531_4 PFAM Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000227 243.0
LZS2_k127_7308531_5 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000000000000000000000000000000000006324 208.0
LZS2_k127_7308531_7 metalloendopeptidase activity - - - 0.000000000000000000002853 95.0
LZS2_k127_7362860_0 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 488.0
LZS2_k127_7362860_1 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003029 256.0
LZS2_k127_7362860_2 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000000000000000000000000000001083 211.0
LZS2_k127_7362860_3 response regulator, receiver K03413,K07662,K07667 - - 0.00000000000000000000000000000000000000000000000000000001625 199.0
LZS2_k127_7362860_4 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.00000000000000000000000000000000000000000003073 162.0
LZS2_k127_7362860_5 - - - - 0.00000000000000000000000000000000000000000004426 161.0
LZS2_k127_7362860_6 - - - - 0.0000000000000000000000000005549 115.0
LZS2_k127_7362860_7 DEAD DEAH box helicase domain protein K03703,K10896 - - 0.0000000001301 61.0
LZS2_k127_7412638_0 Staphylococcal nuclease homologue - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 472.0
LZS2_k127_7412638_1 nucleotidyltransferase activity K07076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005781 330.0
LZS2_k127_7558284_0 TIGRFAM poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 - - 9.365e-226 702.0
LZS2_k127_7558284_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 562.0
LZS2_k127_7558284_2 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 340.0
LZS2_k127_7558284_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007331 237.0
LZS2_k127_7558284_4 phosphoribosyltransferase K07101 - - 0.000000000000000000000000000000000000000000000001608 176.0
LZS2_k127_7558284_6 - - - - 0.00000000000007683 70.0
LZS2_k127_76185_0 Uracil-DNA glycosylase K21929 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 319.0
LZS2_k127_76185_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 293.0
LZS2_k127_7653568_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 1.531e-202 634.0
LZS2_k127_7653568_1 Transporter associated domain - - - 7.616e-200 629.0
LZS2_k127_7653568_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 601.0
LZS2_k127_7653568_3 COG1215 Glycosyltransferases, probably involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 303.0
LZS2_k127_7653568_4 xylanase chitin deacetylase K22278 - 3.5.1.104 0.000000000000000000000000003064 130.0
LZS2_k127_7653568_5 xylanase chitin deacetylase K22278 - 3.5.1.104 0.0000000000000000000000000123 128.0
LZS2_k127_7653568_6 - - - - 0.0000000001131 66.0
LZS2_k127_7667129_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 487.0
LZS2_k127_7667129_1 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 456.0
LZS2_k127_7667129_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 339.0
LZS2_k127_7667129_3 - - - - 0.000000000000000000000000000004547 119.0
LZS2_k127_7667129_4 - - - - 0.000000000000000000000001326 103.0
LZS2_k127_7681450_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 311.0
LZS2_k127_7681450_1 - - - - 0.0000000000000000000000000005486 115.0
LZS2_k127_7681450_2 - - - - 0.00000001981 60.0
LZS2_k127_771445_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 - 2.3.1.234 3.116e-202 631.0
LZS2_k127_771445_1 GTPase of unknown function C-terminal K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 524.0
LZS2_k127_771445_2 Mn2 -dependent serine threonine protein kinase K08851 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004916 295.0
LZS2_k127_771445_3 - - - - 0.0000000000000000000000000000000000000000000000000000000004147 202.0
LZS2_k127_7845329_0 phosphoglycerate mutase K15635 - 5.4.2.12 1.566e-250 776.0
LZS2_k127_7845329_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 5.837e-222 689.0
LZS2_k127_7845329_2 - - - - 0.0000000000000000000000000000000000000005115 151.0
LZS2_k127_7845329_3 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000000000000000000001074 127.0
LZS2_k127_7845329_4 Domain of unknown function (DUF309) - - - 0.0000000008439 67.0
LZS2_k127_7859968_0 inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001672 252.0
LZS2_k127_7859968_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004093 240.0
LZS2_k127_7859968_2 - - - - 0.0000000000000000000000000000000000000000000008129 165.0
LZS2_k127_7859968_3 Uncharacterized conserved protein (DUF2196) - - - 0.0000000000000000000008028 96.0
LZS2_k127_7859968_4 Arsenate reductase and related K00537 - 1.20.4.1 0.0000000001231 61.0
LZS2_k127_7873855_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 2.039e-229 714.0
LZS2_k127_7873855_1 Cobalamin synthesis G C-terminus K02189 - 3.7.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 593.0
LZS2_k127_7873855_2 Cobalt chelatase (CbiK) K06042 - 5.4.99.60,5.4.99.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 475.0
LZS2_k127_7873855_3 Precorrin-8X methylmutase K06042 - 5.4.99.60,5.4.99.61 0.0000000000000000000000000000000000000000000000000000007278 199.0
LZS2_k127_7886616_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 1.496e-210 658.0
LZS2_k127_7886616_1 Fibronectin type 3 domain K22350 - 1.16.3.3 0.0001615 57.0
LZS2_k127_7899182_0 Protein of unknown function, DUF255 K06888 - - 0.0 1239.0
LZS2_k127_7899182_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 481.0
LZS2_k127_7899182_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 366.0
LZS2_k127_7899182_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003146 248.0
LZS2_k127_7899182_4 - - - - 0.000000000000000000000000000000000000000000000000000005709 190.0
LZS2_k127_7899182_5 - - - - 0.0000000000000000000000000000000000000000000000444 171.0
LZS2_k127_7899182_6 - - - - 0.0000000000000000000000000000000002552 134.0
LZS2_k127_7899182_7 - - - - 0.0000000000000000000002955 95.0
LZS2_k127_7918662_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.061e-236 734.0
LZS2_k127_7918662_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 587.0
LZS2_k127_7918662_2 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 503.0
LZS2_k127_7918662_3 Amino acid kinase family K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 468.0
LZS2_k127_7918662_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 389.0
LZS2_k127_7918662_5 Translin family K07477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 354.0
LZS2_k127_7918662_6 NUDIX domain K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 295.0
LZS2_k127_7918662_7 Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S- specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX K17759 - 5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000003519 215.0
LZS2_k127_7918662_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 - 2.7.7.6 0.000000000000000000000000000000000000000001874 156.0
LZS2_k127_7934490_0 argininosuccinate lyase K01755 - 4.3.2.1 1.002e-262 814.0
LZS2_k127_7934490_1 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001987 227.0
LZS2_k127_7934490_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000002323 125.0
LZS2_k127_7937387_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006654 528.0
LZS2_k127_7937387_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 432.0
LZS2_k127_7937387_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 316.0
LZS2_k127_7937387_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006555 272.0
LZS2_k127_7937387_4 - - - - 0.0000000000000000000000000000000000000000000000001723 177.0
LZS2_k127_7937387_5 - - - - 0.0000000008662 59.0
LZS2_k127_7938719_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 7.846e-239 741.0
LZS2_k127_7938719_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 421.0
LZS2_k127_7938719_2 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002596 388.0
LZS2_k127_7938719_3 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 337.0
LZS2_k127_7938719_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001652 277.0
LZS2_k127_7938719_5 - - - - 0.000000000000000000000000000000000000000000000000000000004255 200.0
LZS2_k127_7938719_6 CBS domain K03498 - - 0.00000000000000000000000004849 111.0
LZS2_k127_7942246_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 1.222e-308 949.0
LZS2_k127_7942246_1 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 576.0
LZS2_k127_7942246_10 Dihydrouridine synthase (Dus) - - - 0.0000000000000000007848 86.0
LZS2_k127_7942246_2 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004331 368.0
LZS2_k127_7942246_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 350.0
LZS2_k127_7942246_4 ASCH domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002861 278.0
LZS2_k127_7942246_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004045 273.0
LZS2_k127_7942246_6 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000005612 183.0
LZS2_k127_7942246_7 COG1522 Transcriptional regulators - - - 0.000000000000000000000000000000000000000001121 156.0
LZS2_k127_7942246_9 - - - - 0.00000000000000000000000000000000001532 135.0
LZS2_k127_7955188_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 5.262e-262 809.0
LZS2_k127_7955188_1 Succinyl-CoA ligase like flavodoxin domain K18594 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 440.0
LZS2_k127_7955188_2 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 402.0
LZS2_k127_7955188_3 Toprim domain - - - 0.000000000000000000000000000000000000000000000000000001469 193.0
LZS2_k127_7962214_0 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 6.349e-228 708.0
LZS2_k127_7962214_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 413.0
LZS2_k127_7962214_2 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000551 247.0
LZS2_k127_7962214_3 zinc finger - - - 0.000000000000000000000000000009988 118.0
LZS2_k127_7962214_4 - - - - 0.000000000000000004758 83.0
LZS2_k127_79941_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 392.0
LZS2_k127_79941_1 Protein of unknown function (DUF655) K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 336.0
LZS2_k127_79941_2 Isocitrate isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000008043 190.0
LZS2_k127_79941_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000001997 68.0
LZS2_k127_8000150_0 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 499.0
LZS2_k127_8000150_1 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 290.0
LZS2_k127_8000150_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006328 254.0
LZS2_k127_8000150_3 Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006488 253.0
LZS2_k127_8000150_4 - - - - 0.0000000000000000000001019 100.0
LZS2_k127_8000150_5 - - - - 0.00000000000004815 72.0
LZS2_k127_8009601_0 Peptidase family M3 K08602 - - 0.0 1044.0
LZS2_k127_8009601_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009258 349.0
LZS2_k127_8009601_2 - - - - 0.0000000000000000000000000000000000000000000000000000000006126 204.0
LZS2_k127_8028709_0 Nodulation protein S (NodS) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 415.0
LZS2_k127_8028709_1 Belongs to the MenA family. Type 1 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006052 373.0
LZS2_k127_8028709_2 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 353.0
LZS2_k127_8028709_3 Ribosomal protein S30 K02983 - - 0.00000000000000000000000000001239 117.0
LZS2_k127_8046715_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 0.0 1390.0
LZS2_k127_8046715_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 557.0
LZS2_k127_8046715_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 551.0
LZS2_k127_8046715_3 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 452.0
LZS2_k127_8046715_4 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000000000000000000000000000000000001058 234.0
LZS2_k127_8046715_5 metal-dependent protease of the PAD1 JAB1 superfamily K21140 - 3.13.1.6 0.000000000000000000000000000000000000000000000000000000000000000001878 228.0
LZS2_k127_8046715_6 - - - - 0.0000000000000000000000000000000000000000000000003664 176.0
LZS2_k127_8046715_7 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000000000000000000000003071 147.0
LZS2_k127_8046715_8 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.000000000000000000000000000000004432 128.0
LZS2_k127_8046715_9 PhoU domain K02039 - - 0.0000000000000002954 78.0
LZS2_k127_8055204_0 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 488.0
LZS2_k127_8055204_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 358.0
LZS2_k127_8055204_2 transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 316.0
LZS2_k127_8055204_3 COG0784 FOG CheY-like receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002136 252.0
LZS2_k127_8063122_0 Archaeal Nre, N-terminal - - - 1.301e-215 672.0
LZS2_k127_8063122_1 GTPase of unknown function C-terminal K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008542 523.0
LZS2_k127_8063122_2 Periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 441.0
LZS2_k127_8063122_3 PFAM tRNA synthetases class I (C) catalytic domain K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002308 288.0
LZS2_k127_8063122_4 - - - - 0.0000000000000000000000000000000000000000001038 160.0
LZS2_k127_8068120_0 von Willebrand factor, type A K04043,K07114 - - 5.241e-231 724.0
LZS2_k127_8068120_1 ATPase associated with various cellular activities, AAA_5 K03924,K04748 - - 9.089e-205 638.0
LZS2_k127_8068120_2 - - - - 0.0000000000000000000000000000000000000000007675 163.0
LZS2_k127_8068120_3 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.000000000000000000000000000000002497 130.0
LZS2_k127_8068120_4 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.0000000000000000000000000000408 134.0
LZS2_k127_8068120_5 Archaeal flagellar protein F K07329 - - 0.0000000000000000000003132 103.0
LZS2_k127_8071981_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0 1048.0
LZS2_k127_8071981_1 Histidine kinase K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 520.0
LZS2_k127_8071981_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 486.0
LZS2_k127_8071981_3 transcriptional - - - 0.0000000000000000000000000000000000000000000000000000000004834 213.0
LZS2_k127_8071981_4 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000003359 196.0
LZS2_k127_8071981_5 - - - - 0.000000000000000000000000000000000000009912 147.0
LZS2_k127_8071981_6 Peptidase A24A, prepilin type IV K02278,K07991 - 3.4.23.43,3.4.23.52 0.0000000000000000000003334 105.0
LZS2_k127_8087766_0 resistance protein K14166 - - 0.0 1479.0
LZS2_k127_8087766_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 392.0
LZS2_k127_8087766_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 312.0
LZS2_k127_8087766_3 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000006828 229.0
LZS2_k127_8097083_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 428.0
LZS2_k127_8097083_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 343.0
LZS2_k127_8097083_2 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 308.0
LZS2_k127_8097083_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
LZS2_k127_8152337_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 321.0
LZS2_k127_8152337_1 - - - - 0.000000000000000000000000000000000000000000000000006305 181.0
LZS2_k127_8152337_2 - - - - 0.00000000000000000000000000000000000000000000000002724 181.0
LZS2_k127_8152337_3 - - - - 0.000000000000000000000000000000000000000002976 156.0
LZS2_k127_8152337_4 Mut7-C RNAse domain - - - 0.0000000000000000000000000000000009045 132.0
LZS2_k127_8152337_5 - - - - 0.00000000000000000000000000000002136 130.0
LZS2_k127_8152337_7 - - - - 0.00000000000000000007179 91.0
LZS2_k127_8166419_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 2.959e-313 961.0
LZS2_k127_8166419_1 NADH ubiquinone oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000002723 226.0
LZS2_k127_8166419_2 - - - - 0.0000000000000000000000000000000000000008358 147.0
LZS2_k127_8166419_3 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000005288 108.0
LZS2_k127_8203335_0 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 399.0
LZS2_k127_8203335_1 Radical SAM K06937 - - 0.0000000000000000000000000000000000000000000000004095 175.0
LZS2_k127_8203335_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000001529 157.0
LZS2_k127_8224597_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 1.017e-278 858.0
LZS2_k127_8224597_1 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 347.0
LZS2_k127_8224597_2 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000000000000207 196.0
LZS2_k127_823661_0 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647 - 2.3.3.1 5.986e-237 734.0
LZS2_k127_823661_1 - - - - 0.000000000000000000000000000001964 119.0
LZS2_k127_8275013_0 Adenylate guanylate cyclase with integral membrane sensor - - - 3.005e-255 795.0
LZS2_k127_8275013_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000001903 213.0
LZS2_k127_8275013_2 Ammonium Transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000007877 207.0
LZS2_k127_8285560_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 472.0
LZS2_k127_8285560_1 - - - - 0.000000000000000000000000000000000000000000000000000000000001711 211.0
LZS2_k127_8285560_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000001617 201.0
LZS2_k127_8285560_3 - - - - 0.00000000000000000000000000000000000000000000000005621 179.0
LZS2_k127_8288335_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009889 335.0
LZS2_k127_8288335_1 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005451 252.0
LZS2_k127_8288335_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.00000000000000000000000000000000000000000000000000000000007032 204.0
LZS2_k127_8288335_3 RNA polymerase Rpb3/Rpb11 dimerisation domain K03056 - 2.7.7.6 0.0000000000000000000000000000000000000000000000004448 176.0
LZS2_k127_8288335_4 - - - - 0.00000000000000008315 80.0
LZS2_k127_8289776_0 Iron-containing redox enzyme K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 392.0
LZS2_k127_8289776_1 Transcriptional regulator - - - 0.00000000000000000000000000000000006556 135.0
LZS2_k127_8289776_3 - - - - 0.00000000000005592 73.0
LZS2_k127_8289776_4 Iron-containing redox enzyme K06137 - 1.3.3.11 0.0000000000001888 69.0
LZS2_k127_8289776_5 - - - - 0.000000000006663 72.0
LZS2_k127_8289776_6 Ammonium Transporter K03320 - - 0.00001955 52.0
LZS2_k127_8331155_0 Ribosomal protein L15E K02877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 293.0
LZS2_k127_8331155_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000528 247.0
LZS2_k127_8331155_2 - - - - 0.000000000000000000000000000000000000002773 146.0
LZS2_k127_8331155_3 cheY-homologous receiver domain K03413 - - 0.0000000000002741 71.0
LZS2_k127_841524_0 Required for chromosome condensation and partitioning - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 417.0
LZS2_k127_841524_1 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 291.0
LZS2_k127_841524_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000001985 219.0
LZS2_k127_841524_3 - - - - 0.00000000000000000000000000000002245 127.0
LZS2_k127_8433680_0 COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis K07332 - - 4.402e-277 856.0
LZS2_k127_8433680_1 PFAM type II secretion system K07333 - - 0.0000000000000000000000000000000003492 148.0
LZS2_k127_8433680_2 - - - - 0.000007224 59.0
LZS2_k127_8481794_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 2.446e-249 773.0
LZS2_k127_8481794_1 - - - - 0.000000000000000000000000000000000000000000002561 164.0
LZS2_k127_8481794_2 metallopeptidase activity - - - 0.00000000000000000000000000000000000000002476 156.0
LZS2_k127_8481794_3 - - - - 0.0000000000000000000000002326 105.0
LZS2_k127_8592712_0 Domain of unknown function DUF87 K06915 - - 1.207e-307 945.0
LZS2_k127_8592712_1 NurA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 501.0
LZS2_k127_8592712_2 sister chromatid segregation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 462.0
LZS2_k127_8592712_3 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002144 418.0
LZS2_k127_8592712_4 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000007953 98.0
LZS2_k127_862882_0 FeS assembly protein SufD K09014,K09015 - - 1.739e-270 835.0
LZS2_k127_862882_1 FeS assembly protein SufB K09014 - - 1.48e-246 761.0
LZS2_k127_862882_2 of nitrite reductase and ring-hydroxylating K05710 - - 0.000000000000000000000000000000000000000000000000000000007129 199.0
LZS2_k127_862882_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000002866 60.0
LZS2_k127_8723949_0 Predicted membrane protein (DUF2070) K08979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 511.0
LZS2_k127_8723949_1 Sec61beta family - - - 0.000000000000000000000202 96.0
LZS2_k127_8723949_2 Sjogren's syndrome/scleroderma autoantigen 1 (Autoantigen p27) K07143 - - 0.0000000000408 63.0
LZS2_k127_8740163_0 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 524.0
LZS2_k127_8740163_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004108 458.0
LZS2_k127_8740163_2 protein conserved in archaea K09723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 317.0
LZS2_k127_8740163_3 - - - - 0.00000000000000000000000000000000000000000000000000006197 186.0
LZS2_k127_8740163_4 zinc finger - - - 0.000000000000000000000000000000000000000000008262 163.0
LZS2_k127_88061_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1071.0
LZS2_k127_88061_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.8e-205 640.0
LZS2_k127_8865198_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 341.0
LZS2_k127_8865198_1 A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 325.0
LZS2_k127_8865198_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001453 267.0
LZS2_k127_8865198_3 - - - - 0.0000000000000000000000000000000000000000000000001522 179.0
LZS2_k127_8865198_4 RNA methylase - - - 0.0000000000000000000000000000000000000000000000004899 176.0
LZS2_k127_8865198_5 - - - - 0.00000000000000000000000000000000000000000000002284 171.0
LZS2_k127_8865198_6 - - - - 0.00000001747 56.0