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Overview

ID MAG02234
Name LZS2_bin.84
Sample SMP0056
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order UBA10834
Family UBA10834
Genus UBA9653
Species
Assembly information
Completeness (%) 73.22
Contamination (%) 1.83
GC content (%) 63.0
N50 (bp) 4,781
Genome size (bp) 1,224,607

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1253

Gene name Description KEGG GOs EC E-value Score Sequence
LZS2_k127_1033515_0 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000007713 206.0
LZS2_k127_106406_0 ArsR transcriptional regulator - - - 0.00000000000000000000000000000007232 125.0
LZS2_k127_106406_1 - - - - 0.0000000000000000002133 94.0
LZS2_k127_106406_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000002568 61.0
LZS2_k127_1086027_0 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 388.0
LZS2_k127_1086027_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 297.0
LZS2_k127_1086027_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000004994 79.0
LZS2_k127_1089739_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 388.0
LZS2_k127_1089739_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 389.0
LZS2_k127_1095762_0 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000000000000000007072 219.0
LZS2_k127_1095762_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000005406 80.0
LZS2_k127_1095762_2 Protein of unknown function DUF58 - - - 0.000000002289 66.0
LZS2_k127_1150851_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4.717e-261 831.0
LZS2_k127_1150851_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000003248 156.0
LZS2_k127_1152493_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 479.0
LZS2_k127_1152493_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 432.0
LZS2_k127_1152493_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 380.0
LZS2_k127_1152493_3 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000000000000000006633 173.0
LZS2_k127_1152493_4 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000002817 120.0
LZS2_k127_1152493_5 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.000000000113 75.0
LZS2_k127_1152493_6 - - - - 0.0000001774 62.0
LZS2_k127_1232501_0 MCM OB domain K10726 - - 6.809e-212 681.0
LZS2_k127_1232501_1 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 500.0
LZS2_k127_1232501_10 Protein of unknown function (DUF424) K09148 - - 0.0000001625 61.0
LZS2_k127_1232501_11 RDD family - - - 0.0000009166 57.0
LZS2_k127_1232501_2 FAD binding domain K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 374.0
LZS2_k127_1232501_3 Rad51 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 315.0
LZS2_k127_1232501_4 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 318.0
LZS2_k127_1232501_5 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000001331 244.0
LZS2_k127_1232501_6 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000134 179.0
LZS2_k127_1232501_7 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000001443 168.0
LZS2_k127_1232501_8 ECF-type riboflavin transporter, S component - - - 0.00000000000000000000000001446 117.0
LZS2_k127_1232501_9 Pfam:DUF1628 - - - 0.000000009632 63.0
LZS2_k127_1241759_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000008299 252.0
LZS2_k127_1241759_1 FMN binding K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000006598 168.0
LZS2_k127_1254114_0 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000006442 109.0
LZS2_k127_1254114_1 HAD-hyrolase-like - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009507,GO:0009536,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044424,GO:0044444,GO:0044464 - 0.0003014 47.0
LZS2_k127_1291410_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 467.0
LZS2_k127_1291410_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 391.0
LZS2_k127_1291410_2 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000006603 238.0
LZS2_k127_1291410_3 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000001449 136.0
LZS2_k127_1291410_4 Transcriptional regulator K07108 - - 0.00000002117 61.0
LZS2_k127_1291410_5 - - - - 0.0000001943 61.0
LZS2_k127_1291410_6 - - - - 0.0000002203 61.0
LZS2_k127_1314207_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007218 372.0
LZS2_k127_1314207_1 Sodium:sulfate symporter transmembrane region K14445 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005735 282.0
LZS2_k127_1314207_10 Acetyltransferase (GNAT) domain - - - 0.000000176 63.0
LZS2_k127_1314207_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000004491 172.0
LZS2_k127_1314207_3 PFAM polysaccharide biosynthesis protein - - - 0.0000000000000000000000000002039 131.0
LZS2_k127_1314207_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000008131 117.0
LZS2_k127_1314207_5 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.000000000000000000000003706 105.0
LZS2_k127_1314207_6 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000002668 109.0
LZS2_k127_1314207_7 - K00960 - 2.7.7.6 0.0000000000000000026 85.0
LZS2_k127_1314207_8 YjbR - - - 0.0000000000000003498 84.0
LZS2_k127_1314207_9 - - - - 0.0000000000000009364 81.0
LZS2_k127_1349062_0 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 300.0
LZS2_k127_1349062_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003071 269.0
LZS2_k127_1349062_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000003679 86.0
LZS2_k127_1428326_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 482.0
LZS2_k127_1428326_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000000002882 252.0
LZS2_k127_1428326_2 MafB19-like deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000003501 171.0
LZS2_k127_1428326_3 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000000000008569 167.0
LZS2_k127_1428326_4 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.0000000000000000000445 93.0
LZS2_k127_1428326_5 membrane-associated protein domain - - - 0.000001376 57.0
LZS2_k127_1428326_6 Protein of unknown function (DUF3198) - - - 0.00001114 53.0
LZS2_k127_1435557_0 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005673 371.0
LZS2_k127_1435557_1 Desulfoferrodoxin K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000008949 177.0
LZS2_k127_1435557_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000001409 184.0
LZS2_k127_1435557_3 ABC-type antimicrobial peptide transport system, permease component - - - 0.0000000000000000000000002607 123.0
LZS2_k127_1435557_4 Protein of unknown function (DUF1616) - - - 0.00000002135 65.0
LZS2_k127_1448232_0 phosphoribosylformylglycinamidine cyclo-ligase activity K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 415.0
LZS2_k127_1448232_1 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000001326 265.0
LZS2_k127_1448232_2 Protein of unknown function (DUF531) K09725 - - 0.00000000000000000000000000000000000000000000000000003815 198.0
LZS2_k127_1448232_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000009198 109.0
LZS2_k127_1448232_4 - - - - 0.0003365 45.0
LZS2_k127_1452367_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 3.873e-204 651.0
LZS2_k127_1452367_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 408.0
LZS2_k127_1452367_2 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000001255 243.0
LZS2_k127_1452367_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.0000000000000000000000000000000005567 136.0
LZS2_k127_1452367_4 Methyltransferase domain - - - 0.00000000000000000000000006066 116.0
LZS2_k127_1452367_5 Pfam:DUF59 - - - 0.00000000000000002345 85.0
LZS2_k127_1452367_6 aldo keto reductase family K07079 - - 0.000000000001078 69.0
LZS2_k127_1452367_7 EamA-like transporter family - - - 0.0000001674 62.0
LZS2_k127_1486744_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 365.0
LZS2_k127_1486744_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000001909 233.0
LZS2_k127_1539696_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.6e-254 795.0
LZS2_k127_1539696_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003088 273.0
LZS2_k127_1539696_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000621 182.0
LZS2_k127_1539696_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000001151 108.0
LZS2_k127_1539696_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000002819 105.0
LZS2_k127_1539696_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000003376 92.0
LZS2_k127_1539696_6 PFAM ATP synthase subunit C K02124 - - 0.00000000000000006875 82.0
LZS2_k127_156885_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 545.0
LZS2_k127_156885_1 thymidylate kinase K00943 - 2.7.4.9 0.0000000000000000000000000000000003443 140.0
LZS2_k127_156885_2 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000000005709 136.0
LZS2_k127_1591134_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.27e-254 800.0
LZS2_k127_1591134_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000007435 186.0
LZS2_k127_1594616_0 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000027 213.0
LZS2_k127_1594616_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000009251 188.0
LZS2_k127_1594616_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000002356 179.0
LZS2_k127_1594616_3 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000005761 87.0
LZS2_k127_1594616_4 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.000000000000007137 85.0
LZS2_k127_1613094_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 497.0
LZS2_k127_1613094_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 440.0
LZS2_k127_1613094_2 Major facilitator Superfamily K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001022 268.0
LZS2_k127_1613094_3 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000001266 107.0
LZS2_k127_1667210_0 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003385 223.0
LZS2_k127_1667210_1 - - - - 0.00008509 44.0
LZS2_k127_1692969_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000007335 204.0
LZS2_k127_1692969_1 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000005173 145.0
LZS2_k127_1692969_2 Thiamine-binding protein - - - 0.000000000000000000000009787 106.0
LZS2_k127_1692969_3 PFAM EamA-like transporter family - - - 0.0000000000002041 78.0
LZS2_k127_1693463_0 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 398.0
LZS2_k127_1746818_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001094 284.0
LZS2_k127_1746818_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000003495 199.0
LZS2_k127_1746818_2 response to antibiotic - - - 0.0005006 48.0
LZS2_k127_1747373_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000003823 182.0
LZS2_k127_1747373_1 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000006853 193.0
LZS2_k127_1747373_2 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000008783 130.0
LZS2_k127_1747373_3 - - - - 0.000000000002633 70.0
LZS2_k127_1747373_4 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000005273 68.0
LZS2_k127_1762121_0 4Fe-4S dicluster domain K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007709 299.0
LZS2_k127_1762121_1 molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.000000000000000000000000001218 121.0
LZS2_k127_1762121_2 Radical SAM - - - 0.000000000000000000005054 97.0
LZS2_k127_176732_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000001317 225.0
LZS2_k127_1770076_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 314.0
LZS2_k127_1770076_1 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.000000000000000000000000000000495 126.0
LZS2_k127_1770076_2 Protein of unknown function DUF134 - - - 0.00000000008473 64.0
LZS2_k127_1770076_3 4Fe-4S binding domain K03616 - - 0.0001663 53.0
LZS2_k127_1834065_0 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009655 250.0
LZS2_k127_1834065_1 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000002034 138.0
LZS2_k127_1834065_2 Beta-lactamase superfamily domain - - - 0.00000000002393 64.0
LZS2_k127_1834065_3 response to antibiotic - - - 0.0009007 49.0
LZS2_k127_1918817_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000101 242.0
LZS2_k127_1918817_1 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000002126 133.0
LZS2_k127_1918817_2 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.0000000000000000001898 100.0
LZS2_k127_1942513_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 293.0
LZS2_k127_1942513_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006648 271.0
LZS2_k127_2019592_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000003919 159.0
LZS2_k127_2019592_1 PKD domain - - - 0.00000000000000002654 96.0
LZS2_k127_2026235_0 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001648 268.0
LZS2_k127_2026235_1 PFAM Iron-containing alcohol dehydrogenase K00005,K08317 - 1.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000007415 259.0
LZS2_k127_2026235_2 Protein of unknown function TPD sequence-motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000006017 239.0
LZS2_k127_2026235_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000004146 178.0
LZS2_k127_2035655_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 336.0
LZS2_k127_2035655_1 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001709 332.0
LZS2_k127_2035655_10 JAB/MPN domain K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.000000000001339 76.0
LZS2_k127_2035655_11 histone ubiquitination K10573 GO:0000151,GO:0000209,GO:0000228,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006325,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016043,GO:0016567,GO:0016569,GO:0016570,GO:0016574,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0031371,GO:0031625,GO:0031974,GO:0031981,GO:0032446,GO:0032991,GO:0033503,GO:0033554,GO:0034641,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044454,GO:0044464,GO:0046483,GO:0050896,GO:0051276,GO:0051603,GO:0051716,GO:0061630,GO:0061659,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0090304,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1990234 2.3.2.23 0.000000000007852 74.0
LZS2_k127_2035655_2 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000001207 218.0
LZS2_k127_2035655_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000002581 175.0
LZS2_k127_2035655_4 SIS domain K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000006099 179.0
LZS2_k127_2035655_5 PFAM thioesterase superfamily - - - 0.000000000000000000000000000000000000000005266 161.0
LZS2_k127_2035655_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000003485 144.0
LZS2_k127_2035655_7 PFAM UBA THIF-type NAD FAD binding protein - - - 0.000000000000000000000000000000009255 138.0
LZS2_k127_2035655_8 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000376 131.0
LZS2_k127_2035655_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000005188 94.0
LZS2_k127_2037192_0 TIGRFAM small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 418.0
LZS2_k127_2037192_1 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 311.0
LZS2_k127_2037192_2 Bacterial Na+/H+ antiporter B (NhaB) K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003882 282.0
LZS2_k127_2037192_3 - - - - 0.0000000000000000916 83.0
LZS2_k127_2037192_4 Double zinc ribbon - - - 0.0007249 51.0
LZS2_k127_2078519_0 Cysteine desulfurase - - - 0.0000000000000000000000000000000000000000000008109 176.0
LZS2_k127_2078519_1 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000000000000009886 143.0
LZS2_k127_2078519_2 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000002407 147.0
LZS2_k127_2078519_3 Transcriptional regulator K07730 - - 0.000000000000000000000009316 111.0
LZS2_k127_2078519_4 ABC transporter related K02013 - 3.6.3.34 0.00000000007678 66.0
LZS2_k127_2106097_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 520.0
LZS2_k127_2106097_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.0000000000000000000000000000000000000000000000000000000000000000001369 235.0
LZS2_k127_2106097_2 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000006069 144.0
LZS2_k127_2106097_3 transcriptional regulators - - - 0.00000000003041 70.0
LZS2_k127_2149589_0 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 307.0
LZS2_k127_2149589_1 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.0000000000000000000000000000007668 131.0
LZS2_k127_2153789_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 4.692e-220 696.0
LZS2_k127_2153789_1 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 6.379e-211 673.0
LZS2_k127_2153789_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 378.0
LZS2_k127_2153789_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000001021 258.0
LZS2_k127_2153789_4 Major facilitator superfamily K08177 - - 0.00000000000000000000000000000000000000000000000005006 186.0
LZS2_k127_2153789_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000001387 132.0
LZS2_k127_2161167_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 324.0
LZS2_k127_2161167_1 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000003613 231.0
LZS2_k127_2161167_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000005889 121.0
LZS2_k127_2209913_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1183.0
LZS2_k127_2283416_0 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000003 251.0
LZS2_k127_2283416_1 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000001346 171.0
LZS2_k127_2283416_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000003895 84.0
LZS2_k127_2283416_3 - - - - 0.0005437 49.0
LZS2_k127_2345924_0 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 351.0
LZS2_k127_2345924_1 COG0608 Single-stranded DNA-specific exonuclease K07463 - - 0.0000000000000004459 80.0
LZS2_k127_2345924_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0001411 45.0
LZS2_k127_236556_0 PFAM amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000001554 195.0
LZS2_k127_236556_1 Flavodoxin - - - 0.000002375 54.0
LZS2_k127_2425909_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 2.54e-251 788.0
LZS2_k127_2425909_1 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 514.0
LZS2_k127_2425909_10 - - - - 0.0000000000000000000000000000000000000000000001406 177.0
LZS2_k127_2425909_11 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000001071 158.0
LZS2_k127_2425909_12 - - - - 0.00000000000000000000000000000000001951 143.0
LZS2_k127_2425909_13 - - - - 0.0000000000000000009859 94.0
LZS2_k127_2425909_14 N-acetylglutamate synthase K00619 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1 0.000007103 54.0
LZS2_k127_2425909_2 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000662 331.0
LZS2_k127_2425909_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 315.0
LZS2_k127_2425909_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004992 286.0
LZS2_k127_2425909_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003528 285.0
LZS2_k127_2425909_6 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009647 269.0
LZS2_k127_2425909_7 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000008242 246.0
LZS2_k127_2425909_8 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000001508 193.0
LZS2_k127_2425909_9 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008324,GO:0009847,GO:0015075,GO:0015077,GO:0015081,GO:0015291,GO:0015297,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0032502,GO:0034220,GO:0035725,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000006462 199.0
LZS2_k127_2431967_0 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000001978 230.0
LZS2_k127_2431967_1 PFAM Major Facilitator Superfamily K08177 - - 0.00000000000000000000000000000000000000000839 164.0
LZS2_k127_2431967_2 Protein of unknown function (DUF2797) - - - 0.000001383 59.0
LZS2_k127_2441192_0 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000007444 160.0
LZS2_k127_2441192_1 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.00000000000000000000000000000000000000001456 169.0
LZS2_k127_2441192_2 GvpD gas vesicle protein - - - 0.0000000000000000000000000000000000000003096 157.0
LZS2_k127_2441192_3 cheY-homologous receiver domain - - - 0.0000000000000000006729 93.0
LZS2_k127_2441192_4 Archaeal Type IV pilin, N-terminal - - - 0.0000000008591 70.0
LZS2_k127_2441192_5 PFAM 4-vinyl reductase, 4VR K07013 - - 0.00000001602 57.0
LZS2_k127_2442033_0 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.000000000000000000000000000000000000000000000000000004456 200.0
LZS2_k127_2442033_1 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000002051 159.0
LZS2_k127_2442033_2 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000002519 72.0
LZS2_k127_2456867_0 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009161 294.0
LZS2_k127_2456867_1 transcription regulator activity - - - 0.000000000000000000000000000000000000000005838 162.0
LZS2_k127_2456867_2 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000001305 143.0
LZS2_k127_2456867_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000002247 113.0
LZS2_k127_246025_0 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 370.0
LZS2_k127_246025_1 - - - - 0.000000000000000000000005213 107.0
LZS2_k127_246025_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000000001209 102.0
LZS2_k127_246025_3 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000002327 101.0
LZS2_k127_246025_4 - - - - 0.000008092 57.0
LZS2_k127_2486336_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 458.0
LZS2_k127_2486336_1 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 342.0
LZS2_k127_2493441_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 379.0
LZS2_k127_2493441_1 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 292.0
LZS2_k127_2493441_10 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000005806 130.0
LZS2_k127_2493441_11 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000000002582 129.0
LZS2_k127_2493441_12 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000001432 115.0
LZS2_k127_2493441_13 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001865 85.0
LZS2_k127_2493441_14 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.00000000000000006659 90.0
LZS2_k127_2493441_15 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000003847 73.0
LZS2_k127_2493441_16 - - - - 0.0000000009606 70.0
LZS2_k127_2493441_17 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000006764 51.0
LZS2_k127_2493441_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008362 295.0
LZS2_k127_2493441_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007355 273.0
LZS2_k127_2493441_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000000002099 241.0
LZS2_k127_2493441_5 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000001663 226.0
LZS2_k127_2493441_6 - - - - 0.000000000000000000000000000000000000000000000000000000000003839 229.0
LZS2_k127_2493441_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000004711 206.0
LZS2_k127_2493441_8 Creatinine amidohydrolase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000005125 196.0
LZS2_k127_2493441_9 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000004809 132.0
LZS2_k127_2496830_0 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 481.0
LZS2_k127_2496830_1 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 440.0
LZS2_k127_2496830_2 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 298.0
LZS2_k127_2496830_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000001766 184.0
LZS2_k127_2496830_4 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000000000006832 105.0
LZS2_k127_2496830_5 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.0000000000008578 71.0
LZS2_k127_2525189_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001524 265.0
LZS2_k127_2530234_0 PFAM elongation factor Tu domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 374.0
LZS2_k127_2530234_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000119 154.0
LZS2_k127_2597073_0 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000009984 184.0
LZS2_k127_2597073_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000005844 115.0
LZS2_k127_2597073_2 Belongs to the UPF0292 family - - - 0.00000000000000003662 87.0
LZS2_k127_2597073_3 Belongs to the UPF0235 family K09131 - - 0.000000000004643 70.0
LZS2_k127_2597073_4 protein conserved in archaea K09723 - - 0.0000000001367 70.0
LZS2_k127_2603687_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 302.0
LZS2_k127_2603687_1 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000006506 248.0
LZS2_k127_2603687_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000004982 229.0
LZS2_k127_2603687_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.000000000000000000009366 96.0
LZS2_k127_2604797_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 311.0
LZS2_k127_2604797_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000005558 219.0
LZS2_k127_2604797_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000001282 90.0
LZS2_k127_2611644_0 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 331.0
LZS2_k127_2611644_1 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002644 178.0
LZS2_k127_2611644_2 structural constituent of ribosome K02907 - - 0.000000000000000000000000000000000000000009832 158.0
LZS2_k127_2611644_3 Binds to the 23S rRNA K02876 - - 0.000005069 48.0
LZS2_k127_2735175_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000001097 218.0
LZS2_k127_2735175_1 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.00000000000000000000000000000000000007325 149.0
LZS2_k127_2735175_2 PFAM Rhomboid family protein - - - 0.0000000000000000000003275 105.0
LZS2_k127_2739632_0 KH, type 1, domain K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 292.0
LZS2_k127_2739632_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000001029 250.0
LZS2_k127_2739632_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000000000001462 104.0
LZS2_k127_2739632_3 PFAM response regulator receiver K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000002199 92.0
LZS2_k127_2739632_4 - - - - 0.0000000000000000008301 100.0
LZS2_k127_2740542_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 9.32e-228 717.0
LZS2_k127_2740542_1 PFAM peptidase M20 - - - 0.000000000000000000000002396 109.0
LZS2_k127_2745491_0 helicase superfamily c-terminal domain K03724 - - 1.832e-248 789.0
LZS2_k127_2745491_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000157 111.0
LZS2_k127_2781783_0 ADP-ribosylation factor family - - - 0.0000000000000000014 95.0
LZS2_k127_2781783_1 Acetyltransferase (GNAT) domain - - - 0.000000000000002188 83.0
LZS2_k127_2830450_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 317.0
LZS2_k127_2830450_1 Helix-hairpin-helix motif K07572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008619 243.0
LZS2_k127_2830450_2 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000006095 239.0
LZS2_k127_2830450_3 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000001885 148.0
LZS2_k127_2830450_4 RNA polymerase K03051 - 2.7.7.6 0.00000000000000000000001596 102.0
LZS2_k127_2875109_0 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000000000000000001014 229.0
LZS2_k127_2875109_1 Transcriptional regulators - - - 0.00005299 55.0
LZS2_k127_2886163_1 Ornithine cyclodeaminase/mu-crystallin family K01750,K19244 - 1.4.1.1,4.3.1.12 0.000000000000000000000000003216 117.0
LZS2_k127_2937873_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000228 270.0
LZS2_k127_2937873_1 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis - - - 0.000000000000000000000000000000000001199 142.0
LZS2_k127_2937873_2 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.000000000000000000000000000001606 125.0
LZS2_k127_2937873_3 CobQ/CobB/MinD/ParA nucleotide binding domain - - - 0.000000000000000000000209 100.0
LZS2_k127_295216_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 337.0
LZS2_k127_295216_1 PFAM GHMP kinase K06982 - 2.7.1.169 0.000000000000000000000000000000000000001561 163.0
LZS2_k127_2964774_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008509 368.0
LZS2_k127_2964774_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 348.0
LZS2_k127_2964774_2 shikimate kinase activity K00891 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.71 0.000000000000000000000000000000306 130.0
LZS2_k127_2969479_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 6.758e-287 913.0
LZS2_k127_2969479_1 PFAM Aminotransferase class-III K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 514.0
LZS2_k127_2969479_10 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000003117 107.0
LZS2_k127_2969479_11 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000005891 98.0
LZS2_k127_2969479_12 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000003177 100.0
LZS2_k127_2969479_13 - - - - 0.000000000000001224 77.0
LZS2_k127_2969479_14 Domain of unknown function (DUF296) K06934 - - 0.0000000000001293 76.0
LZS2_k127_2969479_15 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 - - - 0.0000000000003586 80.0
LZS2_k127_2969479_16 - - - - 0.000000000001043 72.0
LZS2_k127_2969479_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 469.0
LZS2_k127_2969479_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 334.0
LZS2_k127_2969479_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000809 295.0
LZS2_k127_2969479_5 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000531 293.0
LZS2_k127_2969479_6 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002048 291.0
LZS2_k127_2969479_7 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000006385 196.0
LZS2_k127_2969479_8 Peptidase family M28 K01439 - 3.5.1.18 0.00000000000000000000000000000000004542 154.0
LZS2_k127_2969479_9 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000697 113.0
LZS2_k127_3042101_0 Citrate transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 474.0
LZS2_k127_3042101_1 Ferrous iron transport B domain protein K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 417.0
LZS2_k127_3042101_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 360.0
LZS2_k127_3042101_3 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000000000576 188.0
LZS2_k127_3042101_4 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00003748 50.0
LZS2_k127_3104053_0 Signal transducing histidine kinase, homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 356.0
LZS2_k127_3104053_1 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.000000000000000000000000000000003133 136.0
LZS2_k127_3104053_2 CheC-like family K03410 - - 0.000000000000000000000000000001221 128.0
LZS2_k127_3109229_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0044237,GO:0044249,GO:0051186,GO:0051188 2.5.1.129 0.00000000000000000000000000000000000000000000000000000001566 206.0
LZS2_k127_3109229_1 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000000000000005397 170.0
LZS2_k127_3109229_2 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000001664 103.0
LZS2_k127_3109229_3 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001544 71.0
LZS2_k127_3109229_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000002104 50.0
LZS2_k127_3109229_5 PFAM Ribosomal protein L31e K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00006289 46.0
LZS2_k127_3125528_0 ABC transporter K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 365.0
LZS2_k127_3125528_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000438 263.0
LZS2_k127_3129477_0 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 360.0
LZS2_k127_3129477_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 344.0
LZS2_k127_3129477_2 haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E K07025 - - 0.000000005469 64.0
LZS2_k127_3129477_3 Periplasmic or secreted lipoprotein - - - 0.00000002355 62.0
LZS2_k127_3141189_0 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 361.0
LZS2_k127_3141189_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000009132 189.0
LZS2_k127_3141189_2 - - - - 0.000000000000002376 79.0
LZS2_k127_3141189_3 PFAM CBS domain - - - 0.0000000000000631 80.0
LZS2_k127_3141189_4 PFAM CBS domain - - - 0.0000000000002113 77.0
LZS2_k127_3141189_5 Permeases of the major facilitator superfamily - - - 0.000000000001287 76.0
LZS2_k127_3176876_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 7.078e-207 650.0
LZS2_k127_3176876_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 390.0
LZS2_k127_3176876_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001015 175.0
LZS2_k127_3176876_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000002854 137.0
LZS2_k127_3187884_0 - - - - 0.0000000000000000000000000000000000000002542 162.0
LZS2_k127_3187884_1 protein conserved in archaea - - - 0.000000000000000000000003579 105.0
LZS2_k127_3187884_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000001715 84.0
LZS2_k127_3235455_0 GtrA-like protein K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007278 278.0
LZS2_k127_3235455_1 Glycosyltransferase Family 4 K13677 - 2.4.1.208 0.00000000000000000000000000000000000000000000006762 183.0
LZS2_k127_3235455_3 membrane K08978 - - 0.00005568 52.0
LZS2_k127_3321733_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 485.0
LZS2_k127_3324088_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 423.0
LZS2_k127_3324088_1 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 379.0
LZS2_k127_3324088_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 356.0
LZS2_k127_3324088_3 dihydropteroate synthase K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000003904 252.0
LZS2_k127_3324088_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000001185 228.0
LZS2_k127_3324088_5 PFAM HhH-GPD family protein K07457 - - 0.000000000000000003878 89.0
LZS2_k127_3333209_0 PFAM Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000002152 224.0
LZS2_k127_3333209_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000000000000000000000000000000000000000000000000000002298 219.0
LZS2_k127_3333209_2 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000141 181.0
LZS2_k127_3333209_3 DEAD/H associated K03724 - - 0.0000000000000000000008239 104.0
LZS2_k127_3333209_4 Double zinc ribbon - - - 0.00004227 56.0
LZS2_k127_3407878_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000001367 188.0
LZS2_k127_3407878_1 TPR Domain containing protein - - - 0.000000000000000000113 104.0
LZS2_k127_3417848_0 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 415.0
LZS2_k127_3417848_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 389.0
LZS2_k127_3417848_2 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 313.0
LZS2_k127_3417848_3 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000009528 150.0
LZS2_k127_3417848_4 Uncharacterized ArCR, COG1888 K09732 - - 0.0000000000000000000000000003713 116.0
LZS2_k127_3417848_5 PFAM Metallophosphoesterase K07096 - - 0.00000000000000000001395 95.0
LZS2_k127_3417848_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000005482 76.0
LZS2_k127_3417848_7 ICC-like phosphoesterases K06953 - - 0.0001502 52.0
LZS2_k127_3449741_0 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000000000000704 192.0
LZS2_k127_3449741_1 Sulfite exporter TauE/SafE - - - 0.0000151 51.0
LZS2_k127_3449741_2 - - - - 0.0007299 50.0
LZS2_k127_3452705_0 Heat shock 70 kDa protein K04043 - - 4.52e-265 829.0
LZS2_k127_3452705_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 389.0
LZS2_k127_3452705_2 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 372.0
LZS2_k127_3452705_3 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008538 301.0
LZS2_k127_3452705_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000004791 198.0
LZS2_k127_3452705_5 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000001227 183.0
LZS2_k127_3452705_6 Domain of unknown function DUF108 K01823,K06989 - 1.4.1.21,5.3.3.2 0.00000000000000000000000000000007589 132.0
LZS2_k127_3452705_7 - - - - 0.0000000000000000000000000000002379 134.0
LZS2_k127_3452705_8 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000007448 117.0
LZS2_k127_3452705_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000004626 106.0
LZS2_k127_3505235_0 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000001026 190.0
LZS2_k127_3516239_0 AsnC family K03718 - - 0.0000000000000000000000000000000001796 139.0
LZS2_k127_3516239_1 Protein of unknown function (DUF835) - - - 0.0000003799 63.0
LZS2_k127_3540606_0 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 338.0
LZS2_k127_3540606_1 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000000000000006901 201.0
LZS2_k127_3540606_2 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.00004194 54.0
LZS2_k127_3540606_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function - - - 0.0000441 51.0
LZS2_k127_3553805_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 506.0
LZS2_k127_3553805_1 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000003879 204.0
LZS2_k127_3557915_0 Aminotransferase class-V K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 362.0
LZS2_k127_3557915_1 aldo keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 355.0
LZS2_k127_3580255_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 4.022e-320 995.0
LZS2_k127_3580255_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 583.0
LZS2_k127_3580255_2 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000943 402.0
LZS2_k127_3580255_3 Helix-turn-helix XRE-family like proteins K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 301.0
LZS2_k127_3580255_4 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 293.0
LZS2_k127_3580255_5 Hsp20/alpha crystallin family K13993 - - 0.0000000000000000000001216 104.0
LZS2_k127_3580255_6 - - - - 0.0000000000000000000003194 109.0
LZS2_k127_3580255_7 Pantothenate synthetase K09722 - 6.3.2.36 0.0000000000000001142 83.0
LZS2_k127_3580255_8 COG3277 RNA-binding protein involved in rRNA processing K07569 - - 0.00003428 49.0
LZS2_k127_3645450_0 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K22503 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 461.0
LZS2_k127_3647851_0 BTB And C-terminal Kelch K10443,K10457 GO:0000003,GO:0000151,GO:0000209,GO:0001655,GO:0001725,GO:0001822,GO:0002009,GO:0003006,GO:0003008,GO:0003014,GO:0003096,GO:0003674,GO:0003779,GO:0005198,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0006996,GO:0007010,GO:0007049,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007293,GO:0007300,GO:0007301,GO:0007349,GO:0008092,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009653,GO:0009887,GO:0009888,GO:0009987,GO:0015629,GO:0015672,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0019953,GO:0022402,GO:0022412,GO:0022414,GO:0030001,GO:0030027,GO:0030029,GO:0030036,GO:0030154,GO:0030163,GO:0030717,GO:0030723,GO:0030725,GO:0031252,GO:0031461,GO:0031463,GO:0032432,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032991,GO:0035183,GO:0035239,GO:0035295,GO:0035324,GO:0036211,GO:0042592,GO:0042641,GO:0042802,GO:0042803,GO:0042995,GO:0043062,GO:0043063,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043412,GO:0043632,GO:0043687,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044421,GO:0044422,GO:0044424,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045171,GO:0045172,GO:0045478,GO:0046983,GO:0048468,GO:0048477,GO:0048513,GO:0048609,GO:0048646,GO:0048729,GO:0048731,GO:0048856,GO:0048869,GO:0048878,GO:0050801,GO:0051179,GO:0051234,GO:0051276,GO:0051321,GO:0051603,GO:0051704,GO:0060429,GO:0060562,GO:0060993,GO:0061326,GO:0061333,GO:0061982,GO:0061988,GO:0065007,GO:0065008,GO:0070192,GO:0070293,GO:0070294,GO:0070647,GO:0070936,GO:0071704,GO:0071840,GO:0072001,GO:0072006,GO:0072009,GO:0072017,GO:0072028,GO:0072073,GO:0072078,GO:0072080,GO:0072088,GO:0072156,GO:0097517,GO:0120025,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1903046,GO:1990234 - 0.0002404 53.0
LZS2_k127_3665304_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 383.0
LZS2_k127_3665304_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 378.0
LZS2_k127_3665304_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000304 256.0
LZS2_k127_3665304_3 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000006333 237.0
LZS2_k127_3665304_4 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000000133 169.0
LZS2_k127_3665304_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000003252 176.0
LZS2_k127_3665304_6 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000003727 110.0
LZS2_k127_3667373_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.795e-218 689.0
LZS2_k127_3667373_1 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 516.0
LZS2_k127_3667373_2 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 400.0
LZS2_k127_3667373_3 helicase superfamily c-terminal domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 404.0
LZS2_k127_3667373_4 Trimethylamine methyltransferase MttB (TMA methyltransferase) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000007555 278.0
LZS2_k127_3667373_5 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000000000005512 128.0
LZS2_k127_3667373_6 protein conserved in archaea - - - 0.000000000000000004109 90.0
LZS2_k127_3667373_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000003027 81.0
LZS2_k127_3667373_8 - - - - 0.0000000118 59.0
LZS2_k127_3676117_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 490.0
LZS2_k127_3676117_1 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000003507 218.0
LZS2_k127_3676117_2 Domain of unknown function (DUF1730) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.0000000000000000007834 97.0
LZS2_k127_3686302_0 RIO1 family K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000006475 213.0
LZS2_k127_3686302_1 K homology RNA-binding domain K06961 - - 0.0000000000000000000000000000000000000000000000002024 183.0
LZS2_k127_3701926_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1293.0
LZS2_k127_3701926_1 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 320.0
LZS2_k127_3701926_2 Fe-S type, tartrate fumarate subfamily, beta K01676,K01678,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000001855 224.0
LZS2_k127_3701926_3 pfam nmd3 K07562 - - 0.0000000000000000000000000000007212 132.0
LZS2_k127_3701926_4 Carboxypeptidase regulatory-like domain K14475 - - 0.0000000000000104 87.0
LZS2_k127_3733106_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 293.0
LZS2_k127_3733106_1 ATPases associated with a variety of cellular activities K16785,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000001741 250.0
LZS2_k127_3733106_2 ATP-binding protein K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000002981 236.0
LZS2_k127_3733106_3 ABC-type cobalt transport system, permease K16785 - - 0.000000000000000000000000000000000000000002486 165.0
LZS2_k127_3733106_4 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000000000001617 104.0
LZS2_k127_3733106_5 - - - - 0.00006627 54.0
LZS2_k127_3733724_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 395.0
LZS2_k127_3733724_1 PFAM DsrE family protein K07092 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000000000000000000000002067 147.0
LZS2_k127_3733724_2 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.00000000000000000000007397 100.0
LZS2_k127_3733724_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.000000000000000001085 91.0
LZS2_k127_3743833_0 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000000000000000000000000000001477 168.0
LZS2_k127_3743833_1 Calcineurin-like phosphoesterase superfamily domain K03547 - - 0.0000000000000000000000000001854 125.0
LZS2_k127_3753267_0 COG0438 Glycosyltransferase K19002 - 2.4.1.337 0.0000000000000000000000000000000000000000000000000000000000000008097 233.0
LZS2_k127_3753267_1 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000006138 191.0
LZS2_k127_3777631_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 359.0
LZS2_k127_3777631_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000956 245.0
LZS2_k127_3777631_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000002547 187.0
LZS2_k127_3777631_3 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000002417 169.0
LZS2_k127_3821055_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 3.089e-240 755.0
LZS2_k127_3821055_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 2.375e-226 724.0
LZS2_k127_3821055_2 oligoendopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 400.0
LZS2_k127_3821055_3 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 302.0
LZS2_k127_3821055_4 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000003237 177.0
LZS2_k127_3821055_5 Roadblock LC7 family protein K07131 - - 0.000000000004501 71.0
LZS2_k127_3821055_6 Flagellar regulatory protein FleQ K10126 - - 0.00000606 50.0
LZS2_k127_3832476_0 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 580.0
LZS2_k127_3832476_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K00836 - 2.6.1.19,2.6.1.76 0.000000000000000000000000000000000000000000005966 168.0
LZS2_k127_3832476_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000007666 115.0
LZS2_k127_3832476_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000006354 83.0
LZS2_k127_3885040_0 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 332.0
LZS2_k127_3885040_1 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003818 258.0
LZS2_k127_3885040_2 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000003429 206.0
LZS2_k127_3916531_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 2.756e-285 893.0
LZS2_k127_3916531_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 516.0
LZS2_k127_3916531_10 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000003368 199.0
LZS2_k127_3916531_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000007629 185.0
LZS2_k127_3916531_12 PRC-barrel domain - - - 0.0000000000000000000000002149 107.0
LZS2_k127_3916531_13 Response regulator receiver domain - - - 0.000000000000000000003429 98.0
LZS2_k127_3916531_14 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000000000407 102.0
LZS2_k127_3916531_15 Acetyltransferase (GNAT) domain - - - 0.00000000001163 76.0
LZS2_k127_3916531_16 but it may be involved in stabilization of the trimeric complex - - - 0.00000000009301 63.0
LZS2_k127_3916531_2 oxidoreductase subunit alpha K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 357.0
LZS2_k127_3916531_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 336.0
LZS2_k127_3916531_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 327.0
LZS2_k127_3916531_5 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 319.0
LZS2_k127_3916531_6 HisG, C-terminal domain K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005165 274.0
LZS2_k127_3916531_7 Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000006435 223.0
LZS2_k127_3916531_8 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000219 213.0
LZS2_k127_3916531_9 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000006527 211.0
LZS2_k127_3921797_0 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.000000000000000000000000000000000000000000000000000002258 198.0
LZS2_k127_3921797_1 - - - - 0.00000000000000000000000003717 114.0
LZS2_k127_3921797_2 NUDIX domain K03574 - 3.6.1.55 0.00000000002873 72.0
LZS2_k127_3951692_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 469.0
LZS2_k127_3951692_1 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000001273 233.0
LZS2_k127_3951692_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000729 131.0
LZS2_k127_3951692_3 Sugar (and other) transporter - - - 0.000000000000000000000000000001741 135.0
LZS2_k127_3982913_0 Domain of unknown function (DUF4910) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 303.0
LZS2_k127_3982913_1 Phosphohydrolase K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000001246 247.0
LZS2_k127_3982913_2 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000006329 168.0
LZS2_k127_3982913_3 EamA-like transporter family K08978 - - 0.00000002316 64.0
LZS2_k127_3999259_0 DNA polymerase type-B family K02319 - 2.7.7.7 2.992e-260 839.0
LZS2_k127_3999259_1 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 339.0
LZS2_k127_3999259_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000003567 99.0
LZS2_k127_4013327_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 477.0
LZS2_k127_4013327_1 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 347.0
LZS2_k127_4013327_2 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 303.0
LZS2_k127_4013327_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000006386 230.0
LZS2_k127_4013327_4 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000005796 203.0
LZS2_k127_4013327_5 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.000000000000004291 76.0
LZS2_k127_4028424_0 AAA domain K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 438.0
LZS2_k127_4028424_1 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000007714 111.0
LZS2_k127_4033402_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.062e-214 669.0
LZS2_k127_4033402_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 446.0
LZS2_k127_4033402_2 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 367.0
LZS2_k127_4033402_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002934 255.0
LZS2_k127_4033402_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.00000000000000000000000000000000003142 145.0
LZS2_k127_4033402_5 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.0000000000000000000000000001318 121.0
LZS2_k127_4033402_6 CAAX protease self-immunity - - - 0.0000000000000000000000000001357 131.0
LZS2_k127_4033402_7 Belongs to the UPF0201 family K09736 - - 0.000000000837 64.0
LZS2_k127_4044655_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 395.0
LZS2_k127_4044655_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000943 274.0
LZS2_k127_4044655_2 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000000000000000000000000000000004228 145.0
LZS2_k127_4044655_3 CARDB - - - 0.00000008677 65.0
LZS2_k127_4076525_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.742e-197 631.0
LZS2_k127_4076525_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 437.0
LZS2_k127_4076525_2 Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000003804 186.0
LZS2_k127_4076525_3 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000005564 164.0
LZS2_k127_4076525_4 Iron-sulphur cluster biosynthesis K15724 - - 0.0000000000000000357 86.0
LZS2_k127_4097490_0 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 314.0
LZS2_k127_4097490_1 Type II/IV secretion system protein - - - 0.000579 49.0
LZS2_k127_4120091_0 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003782 232.0
LZS2_k127_4120091_1 OsmC-like protein - - - 0.0000000000000000000000000000001365 130.0
LZS2_k127_4120091_2 - - - - 0.0000000000000000000000000000849 122.0
LZS2_k127_4120091_3 Aspartate ammonia-lyase K01744 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006531,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008797,GO:0009058,GO:0009066,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019222,GO:0019752,GO:0030162,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1903317,GO:1903319 4.3.1.1 0.0000000000001659 74.0
LZS2_k127_417167_0 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 333.0
LZS2_k127_417167_1 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000002187 178.0
LZS2_k127_417167_2 Oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000001991 159.0
LZS2_k127_417167_3 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000003711 153.0
LZS2_k127_417167_4 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000000000007665 148.0
LZS2_k127_417167_5 PFAM CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000005441 93.0
LZS2_k127_417167_6 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000001858 51.0
LZS2_k127_4206551_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
LZS2_k127_4206551_1 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 308.0
LZS2_k127_4206551_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000001396 221.0
LZS2_k127_4206551_3 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.000000000000000000000000000000000005604 142.0
LZS2_k127_4206551_4 helix_turn_helix ASNC type - GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006355,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009889,GO:0009987,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0016054,GO:0019219,GO:0019222,GO:0019752,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043201,GO:0043436,GO:0043565,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000006496 79.0
LZS2_k127_4206551_5 Bifunctional 3-dehydroquinate dehydratase shikimate dehydrogenase chloroplastic K13832 - 1.1.1.25,4.2.1.10 0.00006038 51.0
LZS2_k127_4237129_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007001 400.0
LZS2_k127_4237129_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 305.0
LZS2_k127_4237129_2 SPFH domain-Band 7 family - - - 0.0000001336 62.0
LZS2_k127_4252195_0 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 379.0
LZS2_k127_4252195_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000004145 211.0
LZS2_k127_4252195_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000001016 197.0
LZS2_k127_4252195_3 Archaeal Peptidase A24 C-terminus Type II K07991 - 3.4.23.52 0.000000000000000000000000004964 121.0
LZS2_k127_4252195_4 PFAM HhH-GPD K07457 - - 0.0000000000000005615 80.0
LZS2_k127_4278810_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003368 546.0
LZS2_k127_4278810_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000009841 207.0
LZS2_k127_4297392_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 316.0
LZS2_k127_4297392_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000003812 191.0
LZS2_k127_4297392_2 SCP-2 sterol transfer family - - - 0.0000000000000123 85.0
LZS2_k127_4297392_3 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000001334 76.0
LZS2_k127_4366987_0 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006325 362.0
LZS2_k127_4366987_1 PFAM Peptidase family M20 M25 M40 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 327.0
LZS2_k127_4366987_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006289 297.0
LZS2_k127_4366987_3 SMART ATPase, AAA type, core K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000002582 249.0
LZS2_k127_4366987_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000001344 199.0
LZS2_k127_4366987_5 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.000000000000000000000000003353 128.0
LZS2_k127_4366987_6 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000001968 102.0
LZS2_k127_4366987_7 Domain of unknown function (DUF749) - - - 0.00004346 49.0
LZS2_k127_4367318_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 GO:0001510,GO:0002128,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000001925 213.0
LZS2_k127_4367318_1 Hexapeptide repeat of succinyl-transferase - - - 0.0000000000000000000000000000000000000000000007983 171.0
LZS2_k127_4367318_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000000000001425 164.0
LZS2_k127_4367318_3 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000000009594 148.0
LZS2_k127_4367318_4 ArsR transcriptional regulator - - - 0.00000000000000000000000000005333 117.0
LZS2_k127_4367318_5 response to oxidative stress K04063 - - 0.000000000005243 72.0
LZS2_k127_4367318_6 PRC-barrel domain protein - - - 0.000000000006597 73.0
LZS2_k127_4367318_7 Glutamine amidotransferases class-II - - - 0.0000000005673 69.0
LZS2_k127_4435454_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009498 270.0
LZS2_k127_4435454_1 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001348 252.0
LZS2_k127_4435454_2 Peptidase family M50 - - - 0.00000000002085 69.0
LZS2_k127_4445100_0 Transcriptional regulator K11924 - - 0.000000000001126 72.0
LZS2_k127_4465063_0 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000328 273.0
LZS2_k127_4465063_1 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000002473 233.0
LZS2_k127_4465063_2 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000002025 55.0
LZS2_k127_4502331_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000321 182.0
LZS2_k127_4502331_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000008183 58.0
LZS2_k127_451256_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 539.0
LZS2_k127_451256_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 381.0
LZS2_k127_451256_2 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000005966 258.0
LZS2_k127_454143_0 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000003599 248.0
LZS2_k127_454143_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.0000000000000000000000000000000000000000425 169.0
LZS2_k127_454143_2 Bacterial PH domain - - - 0.000000001107 65.0
LZS2_k127_4571168_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.00000000000000000000000002354 126.0
LZS2_k127_4571168_1 RNA ligase activity K14415,K18148 GO:0003674,GO:0003824,GO:0003909,GO:0005488,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006396,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0030145,GO:0030312,GO:0033554,GO:0034641,GO:0042245,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:0140098,GO:1901360 6.5.1.3 0.000000000000003802 76.0
LZS2_k127_461944_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 385.0
LZS2_k127_461944_1 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 406.0
LZS2_k127_461944_2 - - - - 0.00000000000000000000005303 103.0
LZS2_k127_461944_3 toxin activity - - - 0.00000000000000000002486 102.0
LZS2_k127_4694963_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 580.0
LZS2_k127_4694963_1 - - - - 0.0000000000000000000000000000000000000000008368 164.0
LZS2_k127_4694963_2 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.0006878 52.0
LZS2_k127_4707644_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 396.0
LZS2_k127_4707644_1 CoA binding domain K01905 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 288.0
LZS2_k127_4707644_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000004228 183.0
LZS2_k127_4713603_0 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000006124 236.0
LZS2_k127_4713603_1 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000006287 210.0
LZS2_k127_4713603_2 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000007792 129.0
LZS2_k127_4713603_3 - - - - 0.0000000000000000000000000000008191 134.0
LZS2_k127_4713603_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000005419 107.0
LZS2_k127_4715837_0 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.7.99.1 4.658e-201 633.0
LZS2_k127_4715837_1 - - - - 0.00000000000000000000000000000000001121 151.0
LZS2_k127_4715837_2 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000000000002828 111.0
LZS2_k127_4789177_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 612.0
LZS2_k127_4789177_1 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000003392 167.0
LZS2_k127_4856626_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 2.688e-214 677.0
LZS2_k127_4856626_1 Integral membrane protein DUF106 - - - 0.0000000000000000000000000000000002351 140.0
LZS2_k127_4856626_2 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003405 108.0
LZS2_k127_4859623_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 2.998e-232 736.0
LZS2_k127_4859623_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 535.0
LZS2_k127_4859623_2 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000002681 165.0
LZS2_k127_4860367_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 326.0
LZS2_k127_4860367_1 transferase activity, transferring glycosyl groups - - - 0.00000004411 63.0
LZS2_k127_4866688_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 524.0
LZS2_k127_4866688_1 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 487.0
LZS2_k127_4866688_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 325.0
LZS2_k127_4866688_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004855 273.0
LZS2_k127_4866688_4 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.000000000000000000000000000000000000000000000000000000002762 209.0
LZS2_k127_4866688_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000006981 199.0
LZS2_k127_4866688_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000001154 193.0
LZS2_k127_4866688_7 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000001601 158.0
LZS2_k127_4866688_8 Ribbon-helix-helix protein, copG family K07722 - - 0.0000000000000000000003955 98.0
LZS2_k127_4887465_0 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000000000000000000000000000000000000000297 247.0
LZS2_k127_4887465_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000002123 211.0
LZS2_k127_4887465_2 - - - - 0.0000000000009113 76.0
LZS2_k127_4891400_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 437.0
LZS2_k127_4891400_1 response to heat K07090 - - 0.0000001174 59.0
LZS2_k127_4903122_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003796 287.0
LZS2_k127_4903122_1 AAA domain - - - 0.0000000000000000000000000000000000000000006357 164.0
LZS2_k127_4903122_2 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000116 118.0
LZS2_k127_4903122_3 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.000000000000001039 89.0
LZS2_k127_4903122_4 - K21029 - 2.7.7.80 0.000000294 55.0
LZS2_k127_4918194_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006796 283.0
LZS2_k127_4918194_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.0000000000000000000000000000000000000000008072 171.0
LZS2_k127_4938342_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 561.0
LZS2_k127_4938342_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 351.0
LZS2_k127_4938342_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009537 269.0
LZS2_k127_4978438_0 Toprim domain K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 426.0
LZS2_k127_4978438_1 Major Facilitator Superfamily - GO:0000003,GO:0003006,GO:0003674,GO:0005215,GO:0005275,GO:0005575,GO:0005623,GO:0005628,GO:0006810,GO:0006811,GO:0006820,GO:0006846,GO:0006847,GO:0006855,GO:0007049,GO:0008150,GO:0009272,GO:0009653,GO:0009987,GO:0010927,GO:0015711,GO:0015718,GO:0015837,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0016043,GO:0019953,GO:0022402,GO:0022413,GO:0022414,GO:0022607,GO:0022857,GO:0030154,GO:0030435,GO:0030437,GO:0030476,GO:0031224,GO:0031505,GO:0032502,GO:0032505,GO:0032989,GO:0034220,GO:0034293,GO:0035433,GO:0042221,GO:0042244,GO:0042493,GO:0042546,GO:0042763,GO:0042764,GO:0042891,GO:0043934,GO:0043935,GO:0044085,GO:0044425,GO:0044464,GO:0044703,GO:0045229,GO:0046942,GO:0048468,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0051179,GO:0051234,GO:0051321,GO:0051704,GO:0055085,GO:0070590,GO:0070591,GO:0070726,GO:0071554,GO:0071555,GO:0071702,GO:0071705,GO:0071840,GO:0071852,GO:0071940,GO:0071944,GO:0098656,GO:1903046,GO:1903825,GO:1905039 - 0.00000000002012 70.0
LZS2_k127_4978438_2 thiamineS protein K03154 - - 0.0000000005405 62.0
LZS2_k127_498541_0 Trimethylamine methyltransferase (MTTB) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001195 267.0
LZS2_k127_498541_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000008888 251.0
LZS2_k127_498541_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
LZS2_k127_498541_3 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000002478 201.0
LZS2_k127_498541_4 Trimethylamine methyltransferase (MTTB) - - - 0.00000000000000000000000000000009414 132.0
LZS2_k127_5011942_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 461.0
LZS2_k127_5011942_1 DnaB-like helicase C terminal domain - - - 0.0000000000000000000001592 107.0
LZS2_k127_5027190_0 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000000000000000000000002837 213.0
LZS2_k127_5027190_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000001985 155.0
LZS2_k127_5027190_2 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000001111 158.0
LZS2_k127_5027190_3 HELICc2 K03722,K10844 - 3.6.4.12 0.000000000000000000000005153 104.0
LZS2_k127_5027190_4 PFAM Forkhead-associated protein - - - 0.000000000000000005883 96.0
LZS2_k127_5033055_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1297.0
LZS2_k127_5033055_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 553.0
LZS2_k127_5033055_2 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 548.0
LZS2_k127_5033055_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005585 418.0
LZS2_k127_5033055_4 4Fe-4S single cluster domain K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 368.0
LZS2_k127_5033055_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000006835 258.0
LZS2_k127_5033055_6 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000000000000000000000009496 203.0
LZS2_k127_5033055_7 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000007853 93.0
LZS2_k127_5118003_0 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001596 276.0
LZS2_k127_5118003_1 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001547 202.0
LZS2_k127_5118003_2 methyltransferase activity - - - 0.000000000000000000000000000000000007761 144.0
LZS2_k127_5118003_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000002315 85.0
LZS2_k127_5132441_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 319.0
LZS2_k127_5132441_1 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000001484 147.0
LZS2_k127_5132441_2 Cysteine desulfurase family protein, VC1184 subfamily - - - 0.00000000000000000000000000000000002389 144.0
LZS2_k127_5132441_3 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.000000000000000000000000000006359 121.0
LZS2_k127_5132441_4 CBS domain K07182 - - 0.00002139 53.0
LZS2_k127_5160160_0 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000006066 236.0
LZS2_k127_5160160_1 - - - - 0.000000000000000000000000000000000000000000005592 184.0
LZS2_k127_5160160_2 Glyoxalase-like domain - - - 0.000000000000000000004472 96.0
LZS2_k127_5201056_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 387.0
LZS2_k127_5201056_1 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000699 238.0
LZS2_k127_5213507_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 516.0
LZS2_k127_5213507_1 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 445.0
LZS2_k127_5245521_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 607.0
LZS2_k127_5245521_1 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000001714 226.0
LZS2_k127_5245521_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000001293 216.0
LZS2_k127_5245521_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000003035 63.0
LZS2_k127_5309773_0 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 455.0
LZS2_k127_5309773_1 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000002326 210.0
LZS2_k127_5309773_2 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000711 111.0
LZS2_k127_5319218_0 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 305.0
LZS2_k127_5319218_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000003943 170.0
LZS2_k127_5319218_2 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000104 48.0
LZS2_k127_5353122_0 DNA polymerase alpha chain like domain K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000005956 238.0
LZS2_k127_5353122_1 Clostripain family - - - 0.0000000000000000000002707 110.0
LZS2_k127_5353122_2 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000003696 92.0
LZS2_k127_5400984_0 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 318.0
LZS2_k127_5400984_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000004407 274.0
LZS2_k127_5400984_11 deoxyhypusine monooxygenase activity - - - 0.000007325 57.0
LZS2_k127_5400984_2 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000175 267.0
LZS2_k127_5400984_3 PFAM PP-loop domain protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001069 252.0
LZS2_k127_5400984_4 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000341 205.0
LZS2_k127_5400984_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.0000000000000000000000000000000000000000000000000000009523 204.0
LZS2_k127_5400984_6 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000002417 193.0
LZS2_k127_5400984_7 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.000000000000000000000000000000000000000000132 167.0
LZS2_k127_5400984_8 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000004002 122.0
LZS2_k127_5402282_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000993 550.0
LZS2_k127_5402282_1 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 476.0
LZS2_k127_5402282_2 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001018 241.0
LZS2_k127_5404290_0 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007374 360.0
LZS2_k127_5404290_1 PFAM Glycosyl transferase, group 1 K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.00000000000000000001583 94.0
LZS2_k127_5404290_2 MarC family integral membrane protein K05595 - - 0.0000000000000001303 94.0
LZS2_k127_5460544_0 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 389.0
LZS2_k127_5460544_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 338.0
LZS2_k127_5460544_2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000004005 269.0
LZS2_k127_5460544_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000000000000000000000000001693 182.0
LZS2_k127_5460544_4 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000002328 78.0
LZS2_k127_5474909_0 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007945 327.0
LZS2_k127_5474909_1 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000000000000000000000001455 221.0
LZS2_k127_5474909_2 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000000797 90.0
LZS2_k127_5474909_3 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000000099 85.0
LZS2_k127_5474909_4 Belongs to the UPF0218 family K09735 - - 0.00000000000000001587 86.0
LZS2_k127_5474909_5 EamA-like transporter family - - - 0.00000000000001576 84.0
LZS2_k127_5474909_6 Protein of unknown function (DUF835) - - - 0.00000000000002562 84.0
LZS2_k127_5474909_7 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000008496 70.0
LZS2_k127_549840_0 CobW/HypB/UreG, nucleotide-binding domain - - - 7.286e-194 614.0
LZS2_k127_549840_1 COG0624 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000005975 177.0
LZS2_k127_549840_2 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000006929 167.0
LZS2_k127_549840_3 - - - - 0.000000000000000000004165 97.0
LZS2_k127_550425_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 574.0
LZS2_k127_550425_1 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002117 286.0
LZS2_k127_550425_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000001158 192.0
LZS2_k127_550425_3 reductase, subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000002827 113.0
LZS2_k127_5511438_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 326.0
LZS2_k127_5511438_1 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 323.0
LZS2_k127_5511438_10 Transcription factor Pcc1 K09741 - - 0.0002418 49.0
LZS2_k127_5511438_2 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 302.0
LZS2_k127_5511438_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000545 302.0
LZS2_k127_5511438_4 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000806 263.0
LZS2_k127_5511438_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000002929 129.0
LZS2_k127_5511438_6 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000005025 99.0
LZS2_k127_5511438_7 binds to the 23S rRNA K02921 - - 0.00000000000000005387 84.0
LZS2_k127_5511438_8 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.00000000002128 65.0
LZS2_k127_5511438_9 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000001316 64.0
LZS2_k127_5539520_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 321.0
LZS2_k127_5539520_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 305.0
LZS2_k127_5539520_10 Major Facilitator - - - 0.000000000000000004877 87.0
LZS2_k127_5539520_11 membrane - - - 0.00000002298 62.0
LZS2_k127_5539520_12 - - - - 0.00000002615 62.0
LZS2_k127_5539520_13 PFAM amino acid-binding ACT domain protein - - - 0.00000004222 60.0
LZS2_k127_5539520_2 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000004521 223.0
LZS2_k127_5539520_3 - - - - 0.00000000000000000000000000000000000000000000000000001804 194.0
LZS2_k127_5539520_4 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000001525 125.0
LZS2_k127_5539520_5 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000124 112.0
LZS2_k127_5539520_6 transcriptional regulators - - - 0.0000000000000000000001202 108.0
LZS2_k127_5539520_7 Transcriptional regulators - - - 0.000000000000000000005729 104.0
LZS2_k127_5539520_8 Clostripain family - - - 0.000000000000000000006367 107.0
LZS2_k127_5539520_9 Methyltransferase type 11 - - - 0.00000000000000000001248 102.0
LZS2_k127_554281_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 399.0
LZS2_k127_554281_1 4Fe-4S binding domain - - - 0.000000000000000002628 90.0
LZS2_k127_561070_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 319.0
LZS2_k127_561070_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000001892 201.0
LZS2_k127_561070_2 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000000000000000000000000000000000000000000000004346 213.0
LZS2_k127_5637228_0 Aminotransferase class-III K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 439.0
LZS2_k127_5637228_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008474 278.0
LZS2_k127_5637228_2 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000008934 212.0
LZS2_k127_5651158_0 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000004869 214.0
LZS2_k127_5651158_1 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000000000000000000008827 111.0
LZS2_k127_5651158_2 Belongs to the UPF0251 family - - - 0.00000000000000000001118 94.0
LZS2_k127_5651158_3 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.0000000000000000006275 95.0
LZS2_k127_5651158_4 PFAM DsrE family protein - - - 0.0000000000000006601 84.0
LZS2_k127_5670667_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
LZS2_k127_5670667_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000004994 65.0
LZS2_k127_5730184_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 560.0
LZS2_k127_5730184_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 296.0
LZS2_k127_5730184_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000003659 261.0
LZS2_k127_5730184_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000006295 232.0
LZS2_k127_5730184_4 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.00000000000000000000000008046 124.0
LZS2_k127_5730184_5 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000002365 68.0
LZS2_k127_5730184_6 - - - - 0.0000000003503 66.0
LZS2_k127_5793605_0 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 449.0
LZS2_k127_5793605_1 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000003227 248.0
LZS2_k127_5793605_2 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.00000000000000000000000000007631 118.0
LZS2_k127_5793605_3 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - GO:0003674,GO:0003824,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111 - 0.000000000001341 68.0
LZS2_k127_5793605_4 Major facilitator superfamily K08222 - - 0.000001151 61.0
LZS2_k127_5892051_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 355.0
LZS2_k127_5906943_0 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000001019 169.0
LZS2_k127_5906943_1 EamA-like transporter family - - - 0.00000000000000824 83.0
LZS2_k127_5926570_0 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 518.0
LZS2_k127_5926570_1 Pfam:KaiC - - - 0.000000000000000000000000000001349 134.0
LZS2_k127_5926570_2 PFAM response regulator receiver - - - 0.0000000000000007926 79.0
LZS2_k127_5926570_3 KaiC - - - 0.0000000001533 62.0
LZS2_k127_5962102_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 308.0
LZS2_k127_5962102_1 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000508 134.0
LZS2_k127_6028989_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000002321 250.0
LZS2_k127_6028989_1 archaeal Zn-finger protein - - - 0.00000000000000000000000000000000000000004754 159.0
LZS2_k127_6028989_2 PFAM Haloacid dehalogenase domain protein hydrolase K01079 - 3.1.3.3 0.000000000000003052 79.0
LZS2_k127_6029606_0 COG0531 Amino acid transporters - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 399.0
LZS2_k127_6029606_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005542 266.0
LZS2_k127_6029606_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007892 249.0
LZS2_k127_6029606_3 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000001291 166.0
LZS2_k127_6029606_4 PFAM NUDIX hydrolase K01515,K03574 - 3.6.1.13,3.6.1.55 0.00000000000000000000000000000000007857 139.0
LZS2_k127_6029606_5 Peptidase family M28 - - - 0.000000000000000000000169 110.0
LZS2_k127_6029606_6 nucleotide metabolic process - - - 0.00000000000000000003145 99.0
LZS2_k127_6029606_7 OmpA family - - - 0.0000000000005269 80.0
LZS2_k127_6029606_8 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000008272 57.0
LZS2_k127_6120634_0 ATPase associated with various cellular activities, AAA_5 K03924,K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003964 257.0
LZS2_k127_6120634_1 FR47-like protein - - - 0.00000000000000001821 89.0
LZS2_k127_6130774_0 PFAM sodium calcium exchanger K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001129 260.0
LZS2_k127_6130774_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000005896 229.0
LZS2_k127_6130774_2 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000009431 171.0
LZS2_k127_6130774_3 Major Facilitator K08151,K08153 - - 0.000000000000000001275 99.0
LZS2_k127_6130774_4 Protein of unknown function (DUF998) - - - 0.00000004844 62.0
LZS2_k127_6205446_0 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 294.0
LZS2_k127_6205446_1 Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004166 246.0
LZS2_k127_6205446_2 Contains one ATP-binding region, ATPase-like domain (IPR003594) K06930 - - 0.00000000000000000000000000003229 123.0
LZS2_k127_6205446_3 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000007467 95.0
LZS2_k127_6205446_4 Rubrerythrin - - - 0.000179 51.0
LZS2_k127_6221209_0 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000001053 159.0
LZS2_k127_6221209_1 4Fe-4S dicluster domain - - - 0.000000004036 68.0
LZS2_k127_625447_0 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000004035 133.0
LZS2_k127_625447_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000002599 91.0
LZS2_k127_6289870_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 6.355e-212 669.0
LZS2_k127_6299997_0 Required for chromosome condensation and partitioning K03529 - - 2.592e-256 833.0
LZS2_k127_6299997_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 454.0
LZS2_k127_6299997_10 PFAM Glycosyl transferases group 1 - - - 0.000000000005559 76.0
LZS2_k127_6299997_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 347.0
LZS2_k127_6299997_3 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000002954 253.0
LZS2_k127_6299997_4 Transferase hexapeptide repeat K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000001999 227.0
LZS2_k127_6299997_5 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000137 200.0
LZS2_k127_6299997_6 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000007151 177.0
LZS2_k127_6299997_7 chromosome segregation and condensation protein ScpA K05896 - - 0.000000000000000000000000000000000000000000000003198 193.0
LZS2_k127_6299997_8 TIGRFAM segregation and condensation protein B K06024 - - 0.0000000000000000000000000000002521 140.0
LZS2_k127_6299997_9 snRNP Sm proteins K04796 - - 0.0000000000000000000000356 100.0
LZS2_k127_6318048_0 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K00343,K22169 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000677 380.0
LZS2_k127_6318048_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000004794 224.0
LZS2_k127_6318048_2 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000003613 217.0
LZS2_k127_6318048_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000005353 90.0
LZS2_k127_6318048_4 FAD dependent oxidoreductase - - - 0.000000000001275 75.0
LZS2_k127_6333327_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000012 247.0
LZS2_k127_6333327_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000008726 235.0
LZS2_k127_6333327_2 Adenylosuccinate lyase C-terminus K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000009657 227.0
LZS2_k127_6333327_3 - K00960 - 2.7.7.6 0.0000000000000001727 79.0
LZS2_k127_6349326_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 454.0
LZS2_k127_6349326_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000003946 239.0
LZS2_k127_6349326_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000008677 135.0
LZS2_k127_6349326_3 TIGRFAM TIGR00304 family protein - - - 0.00005725 48.0
LZS2_k127_6349957_0 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000002195 166.0
LZS2_k127_6349957_1 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000123 94.0
LZS2_k127_6349957_2 Gaf domain K02660,K03406,K11525 - - 0.000000002271 69.0
LZS2_k127_6386755_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000002114 220.0
LZS2_k127_639175_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 625.0
LZS2_k127_639175_1 KEOPS complex Cgi121-like subunit K09119 - - 0.000009527 51.0
LZS2_k127_642760_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000001187 193.0
LZS2_k127_642760_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000231 117.0
LZS2_k127_642760_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.0000000000001128 73.0
LZS2_k127_6449092_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 6.937e-305 953.0
LZS2_k127_6449092_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009444 282.0
LZS2_k127_6449092_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000001384 177.0
LZS2_k127_6456126_0 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000786 168.0
LZS2_k127_6456126_1 - - - - 0.00000000000000000000000000000000001719 145.0
LZS2_k127_6456126_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000004171 119.0
LZS2_k127_6456126_3 - - - - 0.000000000000000002162 93.0
LZS2_k127_6476565_1 phosphoesterase RecJ domain protein K07463 - - 0.00000000000000000000891 94.0
LZS2_k127_6490530_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 390.0
LZS2_k127_6490530_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000001713 262.0
LZS2_k127_6490530_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000824 243.0
LZS2_k127_6492093_0 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 358.0
LZS2_k127_6492093_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 308.0
LZS2_k127_6492093_2 arginine decarboxylase activity K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000006756 259.0
LZS2_k127_650562_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 573.0
LZS2_k127_650562_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000006356 161.0
LZS2_k127_656721_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000001546 210.0
LZS2_k127_656721_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000001254 147.0
LZS2_k127_656721_2 ADP-ribosylation factor family - - - 0.000000000000000000000006236 111.0
LZS2_k127_6616194_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009041 458.0
LZS2_k127_6616194_1 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 371.0
LZS2_k127_6616194_2 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.0000000000000000000000000000000000000000000001431 181.0
LZS2_k127_6627632_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1127.0
LZS2_k127_6627632_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001217 271.0
LZS2_k127_6627632_2 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000002606 205.0
LZS2_k127_6671284_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.428e-267 837.0
LZS2_k127_6671284_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 490.0
LZS2_k127_6671284_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 491.0
LZS2_k127_668531_0 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 472.0
LZS2_k127_668531_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 451.0
LZS2_k127_668531_2 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003435 439.0
LZS2_k127_668531_3 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000004419 219.0
LZS2_k127_6715125_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 552.0
LZS2_k127_6715125_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 423.0
LZS2_k127_6715125_2 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000001588 168.0
LZS2_k127_6715125_3 Cellulose binding domain - - - 0.00000000000008686 85.0
LZS2_k127_6726286_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 2.467e-242 769.0
LZS2_k127_6726286_1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000007364 232.0
LZS2_k127_6726286_2 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000003168 92.0
LZS2_k127_6726286_3 Lrp/AsnC ligand binding domain - - - 0.00007865 48.0
LZS2_k127_6749717_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.00000000000000000000000000003002 123.0
LZS2_k127_6749717_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.000001324 58.0
LZS2_k127_6750153_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00239 - 1.3.5.1,1.3.5.4 2.29e-218 691.0
LZS2_k127_6750153_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000001359 140.0
LZS2_k127_6750153_2 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000006264 91.0
LZS2_k127_6750153_3 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000001992 60.0
LZS2_k127_675276_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 541.0
LZS2_k127_675276_1 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 331.0
LZS2_k127_675276_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000002486 246.0
LZS2_k127_675276_3 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000000004025 162.0
LZS2_k127_675276_4 sodium:proton antiporter activity K05564,K11105 - - 0.000000000000000000000000001809 126.0
LZS2_k127_6800056_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000771 389.0
LZS2_k127_6800056_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000006416 241.0
LZS2_k127_6800056_2 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000004628 162.0
LZS2_k127_6802060_0 Lamin Tail Domain - - - 0.0000000000005838 82.0
LZS2_k127_6802060_1 Sodium hydrogen exchanger - - - 0.00000000008016 66.0
LZS2_k127_6824074_0 PFAM peptidase T2 asparaginase 2 K13051 - 3.4.19.5 0.000000000000000000000000000000000000001783 151.0
LZS2_k127_6824074_1 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.0000000005634 70.0
LZS2_k127_6824074_2 Major Facilitator Superfamily - - - 0.0000001182 58.0
LZS2_k127_6875729_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.265e-214 685.0
LZS2_k127_6875729_1 Helix-hairpin-helix domain K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 546.0
LZS2_k127_6875729_2 serine threonine protein kinase - - - 0.00000000000000000000009262 107.0
LZS2_k127_6875729_3 viral a-type inclusion protein repeat domain-containing protein - - - 0.000007637 59.0
LZS2_k127_6882073_0 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 559.0
LZS2_k127_6882073_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000003589 104.0
LZS2_k127_6882073_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000006908 83.0
LZS2_k127_6882073_3 Archaeal transcriptional regulator TrmB - - - 0.0000000002886 63.0
LZS2_k127_6882153_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 346.0
LZS2_k127_6882153_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 304.0
LZS2_k127_6882153_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000008431 203.0
LZS2_k127_6882153_3 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.0000000000000000000000000000000000000000000004217 171.0
LZS2_k127_6882153_4 oxidoreductase domain - - - 0.0001659 47.0
LZS2_k127_6893364_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 361.0
LZS2_k127_6893364_1 Prokaryotic homologs of the JAB domain - - - 0.000000000000000000000000000000001974 134.0
LZS2_k127_6893364_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000005027 114.0
LZS2_k127_6910008_0 Anticodon binding domain K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006426,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046983,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 617.0
LZS2_k127_6910008_1 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 403.0
LZS2_k127_6910008_2 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006397 268.0
LZS2_k127_6910008_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000002908 196.0
LZS2_k127_6915109_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000002387 203.0
LZS2_k127_6915109_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000009337 190.0
LZS2_k127_6915109_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.000000000000000000000000000000000000000000000006241 175.0
LZS2_k127_6915109_3 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000000000000000001546 121.0
LZS2_k127_6915109_4 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 0.0000000000000000000001428 98.0
LZS2_k127_6915109_5 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000006385 96.0
LZS2_k127_6938811_0 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 500.0
LZS2_k127_6938811_1 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008491 504.0
LZS2_k127_6938811_2 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000001058 206.0
LZS2_k127_6938811_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000002612 162.0
LZS2_k127_6938811_4 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000003652 51.0
LZS2_k127_6940468_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 312.0
LZS2_k127_6940468_1 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000001359 246.0
LZS2_k127_6940468_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000004541 85.0
LZS2_k127_7007040_0 Belongs to the complex I 49 kDa subunit family K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 413.0
LZS2_k127_7007040_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006764 284.0
LZS2_k127_7007040_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001662 232.0
LZS2_k127_7007040_3 B12 binding domain - - - 0.0000000000000000000000000000000001559 134.0
LZS2_k127_7007040_4 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000001687 121.0
LZS2_k127_7007040_5 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.000000000000000000000000004814 114.0
LZS2_k127_7039813_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 514.0
LZS2_k127_7039813_1 Male sterility protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 289.0
LZS2_k127_7039813_2 Oxidoreductase domain protein K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 282.0
LZS2_k127_7039813_3 Trm112p-like protein - - - 0.000000000000000006742 84.0
LZS2_k127_7039813_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0001023 50.0
LZS2_k127_7063364_0 peptidase activity, acting on L-amino acid peptides K09607 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000833 370.0
LZS2_k127_7063364_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 287.0
LZS2_k127_7063364_2 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001765 276.0
LZS2_k127_7063364_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006284 269.0
LZS2_k127_7063364_4 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000007031 101.0
LZS2_k127_7063364_5 Pkd domain containing protein - - - 0.00000000000000003668 93.0
LZS2_k127_7063364_6 Major facilitator superfamily K08222 - - 0.0006962 51.0
LZS2_k127_7102116_0 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
LZS2_k127_7102116_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000135 128.0
LZS2_k127_7102116_2 PFAM Receptor family ligand binding region K01999 - - 0.0000000001691 73.0
LZS2_k127_7102116_3 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000002048 64.0
LZS2_k127_7102116_4 LexA-binding, inner membrane-associated putative hydrolase - - - 0.0005772 49.0
LZS2_k127_7114655_0 MGS-like domain K00602,K01492 - 2.1.2.2,2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 555.0
LZS2_k127_7114655_1 PFAM GvpD gas vesicle - - - 0.00000000000000000000000008467 119.0
LZS2_k127_7114655_2 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000001478 94.0
LZS2_k127_7128937_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 362.0
LZS2_k127_7128937_1 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 309.0
LZS2_k127_7128937_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000335 289.0
LZS2_k127_7128937_3 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009935 251.0
LZS2_k127_7128937_4 homolog of PrgY (pheromone shutdown protein) - - - 0.00000000000000000000000000000000005106 143.0
LZS2_k127_7128937_5 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000001213 99.0
LZS2_k127_7128937_6 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000002974 105.0
LZS2_k127_7128937_7 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000004051 81.0
LZS2_k127_7142610_0 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 353.0
LZS2_k127_7142610_1 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002708 286.0
LZS2_k127_7142610_2 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.00000000000000000001407 91.0
LZS2_k127_7142610_3 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000002502 91.0
LZS2_k127_7190843_0 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002385 280.0
LZS2_k127_7190843_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000009581 259.0
LZS2_k127_7190843_2 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.00000000000000000000000000000000000000000000000000000000000000000004812 256.0
LZS2_k127_7190843_3 B12 binding domain K14084 - - 0.000000000000000000000000000000000000000000000000002174 190.0
LZS2_k127_7190843_4 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000005039 173.0
LZS2_k127_7190843_5 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000009336 158.0
LZS2_k127_7190843_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000006956 112.0
LZS2_k127_7203518_0 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008875 368.0
LZS2_k127_7203518_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 341.0
LZS2_k127_7203518_2 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004182 275.0
LZS2_k127_7210076_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 490.0
LZS2_k127_7210076_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000707 235.0
LZS2_k127_7210076_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000001239 89.0
LZS2_k127_7309698_0 DEAD DEAH box helicase domain protein K05592,K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005636 534.0
LZS2_k127_7309698_1 Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007807 416.0
LZS2_k127_7362953_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 570.0
LZS2_k127_7362953_1 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 396.0
LZS2_k127_7362953_2 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 345.0
LZS2_k127_7362953_3 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000002086 188.0
LZS2_k127_7362953_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000001407 158.0
LZS2_k127_7362953_5 flavin reductase - - - 0.00000000000000000000000000000000000002857 150.0
LZS2_k127_7362953_6 PFAM NIL domain - - - 0.0000000000000000000000000000000005939 135.0
LZS2_k127_7393847_0 4Fe-4S dicluster domain K17996 - 1.12.98.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000269 285.0
LZS2_k127_7393847_1 Oxidoreductase NAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002207 278.0
LZS2_k127_7393847_2 hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000008029 207.0
LZS2_k127_7393847_3 nickel-dependent hydrogenase large subunit - - - 0.00000000000000000000000000005351 121.0
LZS2_k127_7393847_4 - - - - 0.0000000000000000000000000132 112.0
LZS2_k127_7393847_9 - - - - 0.0005298 45.0
LZS2_k127_7400498_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 411.0
LZS2_k127_7400498_1 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001115 277.0
LZS2_k127_7400777_0 - - - - 0.0000000000000000000000000000000000000000000000000000000005506 211.0
LZS2_k127_7400777_1 PUA domain containing protein K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000002179 93.0
LZS2_k127_7452269_0 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000005478 216.0
LZS2_k127_7452269_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000005491 130.0
LZS2_k127_7489081_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 588.0
LZS2_k127_7489081_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 517.0
LZS2_k127_7489081_10 PFAM 4-vinyl reductase, 4VR K07013 - - 0.0000000000000000000009083 101.0
LZS2_k127_7489081_11 Roadblock LC7 family protein K07131 - - 0.000000000000000001592 90.0
LZS2_k127_7489081_12 binds to the 23S rRNA K02922 - - 0.00000000000000001866 82.0
LZS2_k127_7489081_2 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 370.0
LZS2_k127_7489081_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 361.0
LZS2_k127_7489081_4 AMMECR1 K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000001211 233.0
LZS2_k127_7489081_5 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000000000000000000004367 208.0
LZS2_k127_7489081_6 COG1522 Transcriptional regulators - - - 0.00000000000000000000000000000000003481 141.0
LZS2_k127_7489081_7 4Fe-4S binding domain - - - 0.00000000000000000000000000000000003646 139.0
LZS2_k127_7489081_8 Arsenite-activated ATPase ArsA K01551 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.3.16 0.00000000000000000000009209 103.0
LZS2_k127_7489081_9 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000004504 96.0
LZS2_k127_7496439_0 ATPases associated with a variety of cellular activities K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 316.0
LZS2_k127_7496439_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 344.0
LZS2_k127_7496439_2 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000003267 204.0
LZS2_k127_7496439_3 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000001393 201.0
LZS2_k127_7496439_4 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000006038 175.0
LZS2_k127_7496439_5 Sodium Bile acid symporter family K03453 - - 0.00000000000000000000000000000002154 138.0
LZS2_k127_7496439_6 Archaeal Type IV pilin, N-terminal - - - 0.000000003608 71.0
LZS2_k127_7553119_0 Membrane - - - 0.000000000000000000000000000000000000000008363 163.0
LZS2_k127_7553119_1 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000001983 143.0
LZS2_k127_7553119_2 COG0402 Cytosine deaminase and related metal-dependent hydrolases - - - 0.000000000000000000000000000000177 128.0
LZS2_k127_7553119_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000002864 127.0
LZS2_k127_7553119_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.000000000000000001476 87.0
LZS2_k127_7702159_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 552.0
LZS2_k127_7702159_1 - - - - 0.000000000000003196 85.0
LZS2_k127_7706768_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000001188 222.0
LZS2_k127_7706768_1 argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.000000000000000000000000000000000001982 144.0
LZS2_k127_7706768_2 PKD domain - - - 0.0000000211 61.0
LZS2_k127_7728913_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 527.0
LZS2_k127_7741566_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 460.0
LZS2_k127_7741566_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 348.0
LZS2_k127_7741566_2 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 311.0
LZS2_k127_7741566_3 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000269 207.0
LZS2_k127_7741566_4 ribosomal small subunit binding - - - 0.000000008957 65.0
LZS2_k127_7769948_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 601.0
LZS2_k127_7769948_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 299.0
LZS2_k127_7769948_2 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000005532 191.0
LZS2_k127_7769948_3 Acetolactate synthase small K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000003706 105.0
LZS2_k127_7769948_4 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000001352 98.0
LZS2_k127_7783469_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 304.0
LZS2_k127_7783469_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003249 273.0
LZS2_k127_7783469_2 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000005142 198.0
LZS2_k127_7783469_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000001125 108.0
LZS2_k127_7783469_4 - - - - 0.0000000000008661 71.0
LZS2_k127_7783469_6 Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme. - - - 0.0002999 44.0
LZS2_k127_7785605_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.561e-252 796.0
LZS2_k127_7785605_1 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003148 257.0
LZS2_k127_7785605_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000000000000000000000000003985 241.0
LZS2_k127_7785605_3 Nicotinamide-nucleotide adenylyltransferase K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.000000000000000000000000000000000000000000002419 172.0
LZS2_k127_7785605_4 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000001053 149.0
LZS2_k127_7785605_5 PFAM Aminotransferase class I and II K05825 - - 0.0000000000517 64.0
LZS2_k127_7798122_0 GXGXG motif - - - 3.671e-283 908.0
LZS2_k127_7798122_1 Glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 602.0
LZS2_k127_7798122_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 597.0
LZS2_k127_7798122_3 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 410.0
LZS2_k127_7798122_4 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 328.0
LZS2_k127_7798122_5 Nitrite and sulphite reductase 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 325.0
LZS2_k127_7798122_6 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 318.0
LZS2_k127_7798122_7 SpoVT / AbrB like domain - - - 0.00000001873 58.0
LZS2_k127_7803947_0 MMPL family K06994 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 382.0
LZS2_k127_7803947_1 PhoU domain - - - 0.00000000000000000000000000000000000000000000000000000000000000394 228.0
LZS2_k127_7803947_2 - - - - 0.0000000000000005013 90.0
LZS2_k127_7818406_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007287 379.0
LZS2_k127_7818406_1 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001833 273.0
LZS2_k127_7835635_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 605.0
LZS2_k127_7835635_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 467.0
LZS2_k127_7835635_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 406.0
LZS2_k127_7835635_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 321.0
LZS2_k127_7835635_4 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000003835 57.0
LZS2_k127_7875732_0 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000001102 163.0
LZS2_k127_7875732_1 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED K01091 - 3.1.3.18 0.000000000000003607 81.0
LZS2_k127_7875732_2 Rubrerythrin - - - 0.00000000000896 76.0
LZS2_k127_7875732_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000007046 63.0
LZS2_k127_7884586_0 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 324.0
LZS2_k127_7884586_1 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000001796 249.0
LZS2_k127_7884586_2 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000001483 148.0
LZS2_k127_7884586_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000001137 123.0
LZS2_k127_7941933_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 605.0
LZS2_k127_7941933_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 356.0
LZS2_k127_798762_0 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.0000000001078 75.0
LZS2_k127_798762_1 - - - - 0.000001558 55.0
LZS2_k127_8045826_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 8.043e-255 813.0
LZS2_k127_8045826_1 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 307.0
LZS2_k127_8045826_2 VIT family - - - 0.00000000000000000000000000000000006194 141.0
LZS2_k127_8045826_3 COG0310 ABC-type Co2 transport system, permease component K02007 - - 0.000000000000000000000000002823 114.0
LZS2_k127_8045826_4 Ribbon-helix-helix protein, copG family K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000574 115.0
LZS2_k127_8045826_5 SPFH domain-Band 7 family - - - 0.00002869 54.0
LZS2_k127_8049047_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.088e-263 845.0
LZS2_k127_8049047_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 583.0
LZS2_k127_8049047_2 Alanine-glyoxylate amino-transferase K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005055 364.0
LZS2_k127_8049047_3 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 352.0
LZS2_k127_8049047_4 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.00000000000000000000000000000000000000000000000000000000001568 227.0
LZS2_k127_8049047_5 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000001054 198.0
LZS2_k127_8049047_6 MoaE protein K21142 - 2.8.1.12 0.000000000000004942 77.0
LZS2_k127_8049047_7 Di-glucose binding within endoplasmic reticulum - - - 0.00000002303 67.0
LZS2_k127_8049047_8 Uncharacterised protein family (UPF0179) K09730 - - 0.0002003 45.0
LZS2_k127_8091524_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 430.0
LZS2_k127_8091524_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 389.0
LZS2_k127_8091524_2 YHS domain - - - 0.0000000000000002363 83.0
LZS2_k127_8091524_3 COG1522 Transcriptional regulators - - - 0.0009906 45.0
LZS2_k127_8096242_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006157 413.0
LZS2_k127_8096242_1 ribosomal protein S3 K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005723 292.0
LZS2_k127_8096242_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000003927 141.0
LZS2_k127_8096242_11 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000000000000002142 122.0
LZS2_k127_8096242_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000004962 113.0
LZS2_k127_8096242_13 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000971 108.0
LZS2_k127_8096242_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000001362 101.0
LZS2_k127_8096242_15 ribosomal protein S14 K02954 - - 0.000000000000000006609 86.0
LZS2_k127_8096242_16 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000000002951 79.0
LZS2_k127_8096242_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000003141 78.0
LZS2_k127_8096242_18 Ribosomal L29 protein K02904 - - 0.000000000000006419 78.0
LZS2_k127_8096242_19 - - - - 0.00006125 48.0
LZS2_k127_8096242_2 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004107 287.0
LZS2_k127_8096242_20 - - - - 0.00008369 49.0
LZS2_k127_8096242_3 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004856 272.0
LZS2_k127_8096242_4 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000002146 233.0
LZS2_k127_8096242_5 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007441 226.0
LZS2_k127_8096242_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000003227 216.0
LZS2_k127_8096242_7 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002562 204.0
LZS2_k127_8096242_8 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000007592 153.0
LZS2_k127_8096242_9 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000005085 145.0
LZS2_k127_8145943_0 PFAM histone deacetylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000003903 222.0
LZS2_k127_8145943_1 Domain in cystathionine beta-synthase and other proteins. K04767,K07182 - - 0.0000002567 63.0
LZS2_k127_8211234_0 COG0277 FAD FMN-containing dehydrogenases K00102,K00104,K06911 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 520.0
LZS2_k127_8211234_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000007712 261.0
LZS2_k127_8211234_2 PFAM Peptidase - - - 0.0000000000000000000000000000000000000008578 154.0
LZS2_k127_8211234_3 site-specific recombinase - - - 0.000000000000000002371 86.0
LZS2_k127_8211234_4 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.0000000000000009257 81.0
LZS2_k127_8229664_0 Sodium:solute symporter family K03307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 461.0
LZS2_k127_8229664_1 PFAM Iron-containing alcohol dehydrogenase K00005,K08317 - 1.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000004641 263.0
LZS2_k127_8229664_2 PFAM methyltransferase K07755 - 2.1.1.137 0.0000000000000000003095 97.0
LZS2_k127_8229664_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000005871 52.0
LZS2_k127_8229664_4 - - - - 0.0003295 51.0
LZS2_k127_8240739_0 hydrolase (HAD superfamily) K07025 - - 0.00000000000000000000000000000000004286 144.0
LZS2_k127_8240739_1 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000001469 144.0
LZS2_k127_8240739_2 OmpA family K02557,K03286 - - 0.00000001684 68.0
LZS2_k127_8240739_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0006097 53.0
LZS2_k127_8262690_0 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003406 268.0
LZS2_k127_8262690_1 Lamin Tail Domain - - - 0.0000000000000000000000000000000000000000001655 183.0
LZS2_k127_8276971_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00003299 53.0
LZS2_k127_8327117_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 332.0
LZS2_k127_8327117_1 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001308 290.0
LZS2_k127_8327117_10 protein involved in the oxidation of intracellular sulfur K07236 - - 0.0000000000000005399 82.0
LZS2_k127_8327117_11 cytochrome c biogenesis protein K06196 - - 0.00000001054 68.0
LZS2_k127_8327117_12 arsenical-resistance protein K03325 - - 0.0000000789 55.0
LZS2_k127_8327117_13 - - - - 0.0000123 52.0
LZS2_k127_8327117_14 Protein of unknown function (DUF3494) - - - 0.00003602 55.0
LZS2_k127_8327117_2 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000005318 261.0
LZS2_k127_8327117_3 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000005951 175.0
LZS2_k127_8327117_4 DsrE/DsrF-like family K07235 - - 0.000000000000000000000000000002702 123.0
LZS2_k127_8327117_5 Sugar-specific transcriptional regulator TrmB - - - 0.000000000000000000000000005479 114.0
LZS2_k127_8327117_6 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000000000721 108.0
LZS2_k127_8327117_7 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000000000001041 95.0
LZS2_k127_8327117_8 PFAM Bacterial regulatory protein, arsR family - - - 0.0000000000000000001977 93.0
LZS2_k127_8327117_9 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.0000000000000000007769 90.0
LZS2_k127_8328414_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.198e-266 844.0
LZS2_k127_8328414_1 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 450.0
LZS2_k127_8328414_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 419.0
LZS2_k127_8328414_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000002071 94.0
LZS2_k127_8328414_4 Hydrogenase nickel insertion protein HypA K04651 - - 0.000000000005232 70.0
LZS2_k127_8391832_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 449.0
LZS2_k127_8391832_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 371.0
LZS2_k127_8391832_2 Pfam:DUF552 K09152 - - 0.000000000000000000000000000005272 123.0
LZS2_k127_8391832_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000001426 70.0
LZS2_k127_8627046_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 481.0
LZS2_k127_8627046_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 323.0
LZS2_k127_8627046_2 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000002406 219.0
LZS2_k127_8627046_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000005012 191.0
LZS2_k127_8627046_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000002075 158.0
LZS2_k127_8627046_5 TIGRFAM protein translocase SEC61 complex gamma subunit K07342 - - 0.00000000000008982 75.0
LZS2_k127_8660337_0 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 334.0
LZS2_k127_8660337_1 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000000133 113.0
LZS2_k127_8661314_0 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 441.0
LZS2_k127_8661314_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.000000000000000000000000000000000000000000000000002993 191.0
LZS2_k127_8661314_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000005147 184.0
LZS2_k127_8661314_3 Belongs to the UPF0248 family K09715 - - 0.000000000000000000000613 97.0
LZS2_k127_8663422_0 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 413.0
LZS2_k127_8700876_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 591.0
LZS2_k127_8700876_1 peptidase U61, LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000001215 230.0
LZS2_k127_8700876_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000008921 231.0
LZS2_k127_8700876_3 nitroreductase - - - 0.000000000000000000000000000000000000000000000008695 176.0
LZS2_k127_8700876_4 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000005009 156.0
LZS2_k127_8700876_5 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.0000000000000000000000000000000000001048 145.0
LZS2_k127_8700876_6 Protein of unknown function (DUF1616) - - - 0.00000000000000000000002165 107.0
LZS2_k127_8700876_7 EamA-like transporter family - - - 0.000000000000000000000368 108.0
LZS2_k127_8700876_8 - - - - 0.000008367 57.0
LZS2_k127_8786876_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001146 284.0
LZS2_k127_8786876_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000782 146.0
LZS2_k127_8802219_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K08323 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000001186 257.0
LZS2_k127_8802219_1 Uridine phosphorylase - - - 0.0000000000000000000000000000000000000000004046 164.0
LZS2_k127_8802219_2 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000005844 116.0
LZS2_k127_8809328_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000005034 249.0
LZS2_k127_8809328_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000001914 152.0
LZS2_k127_8842870_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001568 252.0
LZS2_k127_8842870_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000002035 134.0
LZS2_k127_8842870_2 protein N-acetylglucosaminyltransferase activity - - - 0.00000000000003567 86.0
LZS2_k127_8842870_3 archaeal coiled-coil protein - - - 0.000003982 53.0
LZS2_k127_8842870_4 Spore coat protein CotH - - - 0.0001901 55.0
LZS2_k127_8846841_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
LZS2_k127_8846841_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000002093 235.0
LZS2_k127_8846841_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000006089 135.0
LZS2_k127_8846841_3 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.00005964 49.0
LZS2_k127_8856758_0 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 349.0
LZS2_k127_8856758_1 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000002985 162.0
LZS2_k127_8856758_2 Saccharopine dehydrogenase C-terminal domain - - - 0.0002003 45.0
LZS2_k127_8856758_3 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0008741 42.0
LZS2_k127_8922395_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 592.0
LZS2_k127_8922395_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 311.0
LZS2_k127_8922395_2 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.00000000000000000000000000000000000000000000000000178 193.0
LZS2_k127_8922395_3 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000007341 190.0
LZS2_k127_8922395_4 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000000000000003448 177.0
LZS2_k127_8922395_5 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000009692 168.0
LZS2_k127_8922395_6 - - - - 0.000001773 55.0
LZS2_k127_904514_0 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000000000000003678 194.0
LZS2_k127_904514_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000003598 172.0
LZS2_k127_904514_2 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000001387 91.0
LZS2_k127_904514_3 4Fe-4S dicluster domain - - - 0.000000000000000000512 90.0
LZS2_k127_941647_0 acetyl-CoA hydrolase transferase - - - 2.887e-220 702.0
LZS2_k127_941647_1 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 368.0
LZS2_k127_941647_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008805 278.0
LZS2_k127_941647_3 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00002712 53.0
LZS2_k127_968073_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 327.0
LZS2_k127_968073_1 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002024 276.0
LZS2_k127_968073_2 pathogenesis K18286,K20276 - 3.5.4.40 0.00000000002672 76.0
LZS2_k127_968073_3 amine dehydrogenase activity - - - 0.00000001277 67.0
LZS2_k127_987036_0 Type II/IV secretion system protein K07332 - - 4.4e-226 714.0
LZS2_k127_987036_1 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002286 286.0
LZS2_k127_987036_2 Type II secretion system K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000007579 233.0
LZS2_k127_987036_3 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000209 190.0