logo

Overview

ID MAG02354
Name MMD2_bin.10
Sample SMP0059
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-39
Genus JAOUFA01
Species
Assembly information
Completeness (%) 83.43
Contamination (%) 0.61
GC content (%) 68.0
N50 (bp) 11,400
Genome size (bp) 2,623,868

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2596

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1037613_0 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 584.0
MMD2_k127_1037613_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 509.0
MMD2_k127_1037613_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 361.0
MMD2_k127_1037613_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000009833 265.0
MMD2_k127_1037613_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000002843 229.0
MMD2_k127_1037613_5 periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000004672 157.0
MMD2_k127_1037613_6 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000001229 117.0
MMD2_k127_1037613_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000004221 86.0
MMD2_k127_1037613_8 - - - - 0.0000000000000002331 93.0
MMD2_k127_1058344_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.605e-245 768.0
MMD2_k127_1058344_1 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 565.0
MMD2_k127_1058344_2 Sulfite reductase K00381 - 1.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 456.0
MMD2_k127_1058344_3 Transcriptional regulator K13634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 423.0
MMD2_k127_1058344_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001793 259.0
MMD2_k127_1058344_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000004211 216.0
MMD2_k127_1058344_6 - - - - 0.00000000001059 79.0
MMD2_k127_1074621_0 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 5.453e-217 689.0
MMD2_k127_1074621_1 homoserine dehydrogenase K00003 - 1.1.1.3 1.422e-210 662.0
MMD2_k127_1074621_2 Threonine synthase K01733 - 4.2.3.1 1.587e-205 671.0
MMD2_k127_1074621_3 Aminotransferase class I and II K14261 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 362.0
MMD2_k127_1074621_4 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K13642 - - 0.00000000005958 73.0
MMD2_k127_1112077_0 Glycosyl transferase family, a/b domain K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 451.0
MMD2_k127_1112077_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 328.0
MMD2_k127_1112077_2 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 318.0
MMD2_k127_1112077_3 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 294.0
MMD2_k127_1112077_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003267 249.0
MMD2_k127_1112077_5 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000001154 243.0
MMD2_k127_1112077_6 regulator of disulfide bond formation K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000003428 236.0
MMD2_k127_1112077_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000001866 229.0
MMD2_k127_1125073_0 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 567.0
MMD2_k127_1125073_1 AAA domain (Cdc48 subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 481.0
MMD2_k127_1125073_2 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 422.0
MMD2_k127_1125073_3 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 344.0
MMD2_k127_1125073_4 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 322.0
MMD2_k127_1125073_5 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000002408 192.0
MMD2_k127_1125073_6 Cytochrome c - - - 0.000000000000000000000000000000000001572 141.0
MMD2_k127_1125073_7 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000104 124.0
MMD2_k127_1125073_8 cytochrome - - - 0.000000000000000000000001074 113.0
MMD2_k127_1148931_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 5.297e-196 619.0
MMD2_k127_1148931_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009414 547.0
MMD2_k127_1148931_10 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003335 250.0
MMD2_k127_1148931_11 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000004764 222.0
MMD2_k127_1148931_12 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000006131 199.0
MMD2_k127_1148931_13 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000006681 196.0
MMD2_k127_1148931_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000134 140.0
MMD2_k127_1148931_15 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000002527 133.0
MMD2_k127_1148931_16 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000004471 68.0
MMD2_k127_1148931_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 544.0
MMD2_k127_1148931_3 Domain of unknown function (DUF4147) K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 534.0
MMD2_k127_1148931_4 Benzoate membrane transport protein K05782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 499.0
MMD2_k127_1148931_5 Gentisate 1,2-dioxygenase K00450 - 1.13.11.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 474.0
MMD2_k127_1148931_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005661 344.0
MMD2_k127_1148931_7 esterase K01432 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002232 282.0
MMD2_k127_1148931_8 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004107 265.0
MMD2_k127_1148931_9 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008307 258.0
MMD2_k127_1152946_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 4.665e-215 674.0
MMD2_k127_1152946_1 4,5-dihydroxyphthalate decarboxylase K04102 - 4.1.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 491.0
MMD2_k127_1152946_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 404.0
MMD2_k127_1152946_3 peptidase, M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 327.0
MMD2_k127_1152946_4 LysR substrate binding domain K19338 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001309 276.0
MMD2_k127_1152946_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001039 264.0
MMD2_k127_1152946_6 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000004487 224.0
MMD2_k127_1152946_7 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001778 228.0
MMD2_k127_1152946_8 Putative mono-oxygenase ydhR - - - 0.0000000000000000000001052 101.0
MMD2_k127_1156263_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.946e-194 615.0
MMD2_k127_1156263_1 chemotaxis K03406,K05875 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 472.0
MMD2_k127_1156263_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000866 372.0
MMD2_k127_1156263_3 dihydropteroate synthase K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 334.0
MMD2_k127_1156263_4 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000004239 206.0
MMD2_k127_1156263_5 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0000000000000000000000000000000000000001848 151.0
MMD2_k127_1196054_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 612.0
MMD2_k127_1196054_1 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 595.0
MMD2_k127_1196054_10 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000008211 239.0
MMD2_k127_1196054_11 Histidine phosphatase superfamily (branch 1) - - - 0.000000000000000000000000000000000000000000000000000006058 198.0
MMD2_k127_1196054_12 - - - - 0.000000000000000000000000000000000000000000000000000006921 214.0
MMD2_k127_1196054_13 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000000000000000472 183.0
MMD2_k127_1196054_14 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000002678 178.0
MMD2_k127_1196054_15 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000001133 149.0
MMD2_k127_1196054_17 - - - - 0.000002448 61.0
MMD2_k127_1196054_2 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 524.0
MMD2_k127_1196054_3 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 427.0
MMD2_k127_1196054_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 367.0
MMD2_k127_1196054_5 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 368.0
MMD2_k127_1196054_6 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 383.0
MMD2_k127_1196054_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001656 265.0
MMD2_k127_1196054_8 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002016 281.0
MMD2_k127_1196054_9 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002562 261.0
MMD2_k127_1204261_0 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 490.0
MMD2_k127_1204261_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 462.0
MMD2_k127_1204261_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 334.0
MMD2_k127_1204261_3 Competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005177 271.0
MMD2_k127_1204261_4 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002738 256.0
MMD2_k127_1226326_0 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 0.0 1034.0
MMD2_k127_1226326_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 4.567e-224 726.0
MMD2_k127_1226326_10 PFAM OmpA MotB domain protein K02557 - - 0.0000000000000000000000000000000000002547 149.0
MMD2_k127_1226326_11 Ring hydroxylating subunit beta family protein 1 - - - 0.0000000000000000000000000000001376 136.0
MMD2_k127_1226326_12 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000003628 68.0
MMD2_k127_1226326_13 Protein of unknown function (DUF2892) - - - 0.00000000346 61.0
MMD2_k127_1226326_2 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 2.553e-216 692.0
MMD2_k127_1226326_3 Rieske 2Fe-2S domain protein K14748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 418.0
MMD2_k127_1226326_4 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 336.0
MMD2_k127_1226326_5 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 321.0
MMD2_k127_1226326_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001633 297.0
MMD2_k127_1226326_7 PFAM regulatory protein, MarR - - - 0.000000000000000000000000000000000000000000000000006278 187.0
MMD2_k127_1226326_8 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000002248 183.0
MMD2_k127_1226326_9 OsmC-like protein - - - 0.000000000000000000000000000000000000000001375 161.0
MMD2_k127_1250454_0 CoA-binding domain protein K09181 - - 0.0 1071.0
MMD2_k127_1250454_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 4.949e-318 987.0
MMD2_k127_1250454_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 4.477e-289 905.0
MMD2_k127_1250454_3 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 496.0
MMD2_k127_1250454_4 Belongs to the aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 440.0
MMD2_k127_1250454_5 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000001341 235.0
MMD2_k127_1250454_6 Sulphur oxidation protein SoxZ K17227 - - 0.000000000000000000000000000009136 121.0
MMD2_k127_1250454_7 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000004641 129.0
MMD2_k127_1250454_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000003757 79.0
MMD2_k127_1253750_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.4e-323 1001.0
MMD2_k127_1253750_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 325.0
MMD2_k127_1253750_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 309.0
MMD2_k127_1253750_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 310.0
MMD2_k127_1253750_4 cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000006281 196.0
MMD2_k127_1253750_5 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000000001807 153.0
MMD2_k127_1253750_6 Belongs to the UPF0434 family K09791 - - 0.00000000000000000000003422 102.0
MMD2_k127_128492_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 492.0
MMD2_k127_128492_1 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 463.0
MMD2_k127_128492_10 ATP ADP translocase K03301 - - 0.00000000000001479 78.0
MMD2_k127_128492_2 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 456.0
MMD2_k127_128492_3 Dehydrogenase K15054 - 1.1.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 411.0
MMD2_k127_128492_4 Belongs to the DapA family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 398.0
MMD2_k127_128492_5 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 336.0
MMD2_k127_128492_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 310.0
MMD2_k127_128492_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.0000000000000000000000000000000000000000000000000000000000000000000000001434 252.0
MMD2_k127_128492_8 TLC ATP/ADP transporter K03301 - - 0.00000000000000000000000000001243 127.0
MMD2_k127_128492_9 - - - - 0.00000000000000000000000002174 116.0
MMD2_k127_1307438_0 Domain of unknown function (DUF3400) - - - 0.0 1768.0
MMD2_k127_1307438_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1150.0
MMD2_k127_1307438_10 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000008396 209.0
MMD2_k127_1307438_11 Histidine triad (HIT) - - - 0.00000000000000000000000000000000000000005638 157.0
MMD2_k127_1307438_12 Protein of unknown function (DUF2782) - - - 0.0000003145 58.0
MMD2_k127_1307438_13 Tripartite tricarboxylate transporter family receptor - - - 0.0003718 44.0
MMD2_k127_1307438_2 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 376.0
MMD2_k127_1307438_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 344.0
MMD2_k127_1307438_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 329.0
MMD2_k127_1307438_5 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
MMD2_k127_1307438_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
MMD2_k127_1307438_7 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001024 240.0
MMD2_k127_1307438_8 - - - - 0.00000000000000000000000000000000000000000000000000000002923 205.0
MMD2_k127_1307438_9 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001438 197.0
MMD2_k127_1376160_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.245e-297 927.0
MMD2_k127_1376160_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 569.0
MMD2_k127_1376160_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006502 560.0
MMD2_k127_1376160_3 response regulator K07715 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 486.0
MMD2_k127_1376160_4 His Kinase A (phospho-acceptor) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 347.0
MMD2_k127_1376160_5 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 354.0
MMD2_k127_1376160_6 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000005705 191.0
MMD2_k127_1376160_7 Dihydrofolate reductase K00287 - 1.5.1.3 0.000000000000000000000000000000000000000000000000005203 186.0
MMD2_k127_1376160_8 Major Facilitator Superfamily - - - 0.000000002035 70.0
MMD2_k127_1376160_9 DNA-sulfur modification-associated - - - 0.00008768 54.0
MMD2_k127_1377168_0 COG0210 Superfamily I DNA and RNA helicases K03657 - 3.6.4.12 3.846e-245 776.0
MMD2_k127_1377168_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016043,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0022607,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 476.0
MMD2_k127_1377168_10 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000000005097 143.0
MMD2_k127_1377168_12 NADPH-dependent FMN reductase K19784 - - 0.0000000007831 61.0
MMD2_k127_1377168_13 Phosphopantetheine attachment site K02078 - - 0.000000001221 63.0
MMD2_k127_1377168_2 Belongs to the beta-ketoacyl-ACP synthases family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 365.0
MMD2_k127_1377168_3 Beta-lactamase K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 345.0
MMD2_k127_1377168_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 327.0
MMD2_k127_1377168_5 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004263 277.0
MMD2_k127_1377168_6 major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001121 297.0
MMD2_k127_1377168_7 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006874 251.0
MMD2_k127_1377168_8 Alpha/beta hydrolase family K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000005592 255.0
MMD2_k127_1377168_9 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000001195 220.0
MMD2_k127_1415891_0 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 383.0
MMD2_k127_1415891_1 PFAM metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 306.0
MMD2_k127_1415891_2 Universal stress protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000001886 245.0
MMD2_k127_1415891_3 Thioesterase superfamily - - - 0.00000000000000000000000000000000003568 139.0
MMD2_k127_1415891_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000004294 114.0
MMD2_k127_1415891_5 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 0.0000000000000000000001323 100.0
MMD2_k127_142029_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 6.257e-251 780.0
MMD2_k127_142029_1 Poly-beta-hydroxybutyrate K03821 - - 4.354e-249 783.0
MMD2_k127_142029_10 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000009655 185.0
MMD2_k127_142029_11 - - - - 0.000000000000000000000000000000000000000000000572 184.0
MMD2_k127_142029_12 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000000001862 140.0
MMD2_k127_142029_13 RND efflux system, outer membrane lipoprotein, NodT family - - - 0.000000000000000000000000000000000212 143.0
MMD2_k127_142029_14 Tfp pilus assembly protein, major pilin PilA K02650 - - 0.00000000000000000000000000003453 121.0
MMD2_k127_142029_15 regulator - - - 0.00000000000000000000000008473 115.0
MMD2_k127_142029_16 Response regulator receiver - - - 0.00000000000000003631 88.0
MMD2_k127_142029_17 ABC-type polar amino acid transport system ATPase component K09972 - - 0.000005895 55.0
MMD2_k127_142029_2 PFAM Enoyl-CoA hydratase isomerase K15513 - 4.1.2.44 9.057e-240 762.0
MMD2_k127_142029_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 448.0
MMD2_k127_142029_4 Shikimate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004692 254.0
MMD2_k127_142029_5 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000553 271.0
MMD2_k127_142029_6 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002646 259.0
MMD2_k127_142029_7 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000003525 237.0
MMD2_k127_142029_8 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000009616 207.0
MMD2_k127_142029_9 Permease MlaE - - - 0.000000000000000000000000000000000000000000000000004821 190.0
MMD2_k127_1439300_0 Diguanylate cyclase - - - 4.852e-230 727.0
MMD2_k127_1439300_1 PFAM Amidohydrolase 3 - - - 5.903e-201 640.0
MMD2_k127_1439300_10 SMART Signal transduction response regulator, receiver region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008675 251.0
MMD2_k127_1439300_11 PFAM Heme NO binding - - - 0.000000000000000000000000000000000000008861 167.0
MMD2_k127_1439300_12 PFAM PspC domain K03973 - - 0.000000000000000001485 91.0
MMD2_k127_1439300_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001856 388.0
MMD2_k127_1439300_3 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 375.0
MMD2_k127_1439300_4 Aldo/keto reductase family K05275 - 1.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 327.0
MMD2_k127_1439300_5 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 349.0
MMD2_k127_1439300_6 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 318.0
MMD2_k127_1439300_7 Belongs to the binding-protein-dependent transport system permease family K01997,K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 298.0
MMD2_k127_1439300_8 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
MMD2_k127_1439300_9 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002131 290.0
MMD2_k127_1470229_0 Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor K00697 - 2.4.1.15,2.4.1.347 4.262e-316 985.0
MMD2_k127_1470229_1 Belongs to the peptidase S1C family K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006149 401.0
MMD2_k127_1470229_2 Histidine kinase K02484,K07645 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 349.0
MMD2_k127_1470229_3 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 316.0
MMD2_k127_1470229_4 GDP-mannose 4,6 dehydratase K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000002686 180.0
MMD2_k127_1470229_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000008233 74.0
MMD2_k127_1470229_6 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000004471 51.0
MMD2_k127_1476168_0 RDD family - - - 0.000000000000000000000000000000000000000000000000000000003802 207.0
MMD2_k127_1476168_1 - - - - 0.000000000000000000000000000000000000000000001062 183.0
MMD2_k127_1476168_2 Belongs to the UPF0311 family - - - 0.000000000000000000000000000000000000000000001345 170.0
MMD2_k127_1476168_3 Stage II sporulation protein M - - - 0.00000000006109 64.0
MMD2_k127_1476168_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000001525 57.0
MMD2_k127_1479508_0 FAD binding domain K07077 - - 1.2e-209 665.0
MMD2_k127_1479508_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003278 280.0
MMD2_k127_1479508_2 Bacterial regulatory proteins, tetR family K16137 - - 0.0000000000000000000000000000000000000000000000000000004029 201.0
MMD2_k127_1479508_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000748 132.0
MMD2_k127_1479752_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 0.0 1166.0
MMD2_k127_1479752_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 616.0
MMD2_k127_1479752_2 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008097 388.0
MMD2_k127_1479752_3 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 362.0
MMD2_k127_1479752_4 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000006206 169.0
MMD2_k127_1479752_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000001284 140.0
MMD2_k127_1479752_6 Response regulator receiver K02658 - - 0.00000000000000000000000000005816 125.0
MMD2_k127_1479752_7 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000001852 115.0
MMD2_k127_1479752_8 - - - - 0.00000003202 62.0
MMD2_k127_1503962_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1447.0
MMD2_k127_1503962_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.573e-308 951.0
MMD2_k127_1503962_2 TIGRFAM Phosphoserine phosphatase SerB K01079 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001888 277.0
MMD2_k127_1503962_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000005756 269.0
MMD2_k127_1503962_4 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0000027,GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008650,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000001914 229.0
MMD2_k127_1503962_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000002608 175.0
MMD2_k127_1503962_6 COG1192 ATPases involved in chromosome partitioning K03496 - - 0.00000000000000000000000000000000000000000000004552 178.0
MMD2_k127_1539871_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1335.0
MMD2_k127_1539871_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 589.0
MMD2_k127_1539871_10 DsrE/DsrF-like family K07092 - - 0.000000000000000000000000000000000000000000001659 169.0
MMD2_k127_1539871_11 iron ion homeostasis - - - 0.00000000000000000000000000000000000000000001198 170.0
MMD2_k127_1539871_12 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000000000000000000000000000000000005705 161.0
MMD2_k127_1539871_13 Sulfurtransferase TusA K04085 - - 0.00000000000000000000000000000002115 128.0
MMD2_k127_1539871_14 PFAM biotin lipoate A B protein ligase - - - 0.000000000000000000000000005583 119.0
MMD2_k127_1539871_15 COG0840 Methyl-accepting chemotaxis protein - - - 0.000000004699 59.0
MMD2_k127_1539871_16 - - - - 0.00006246 54.0
MMD2_k127_1539871_2 radical SAM K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 557.0
MMD2_k127_1539871_3 SMART Elongator protein 3 MiaB NifB K09711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 435.0
MMD2_k127_1539871_4 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 375.0
MMD2_k127_1539871_5 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006753 256.0
MMD2_k127_1539871_6 Catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes K03800 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0017118,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000001212 232.0
MMD2_k127_1539871_7 Glycine cleavage H-protein K02437 - - 0.000000000000000000000000000000000000000000000000000000007987 207.0
MMD2_k127_1539871_8 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000002445 195.0
MMD2_k127_1539871_9 Haem-degrading - - - 0.000000000000000000000000000000000000000000000001019 189.0
MMD2_k127_1552801_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 2.213e-264 828.0
MMD2_k127_1552801_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 3.276e-258 811.0
MMD2_k127_1552801_10 Glutamate-cysteine ligase K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 592.0
MMD2_k127_1552801_11 Major facilitator superfamily K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005217 576.0
MMD2_k127_1552801_12 Cobalamin-independent synthase, Catalytic domain K00549,K22363 - 2.1.1.14,4.4.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 562.0
MMD2_k127_1552801_13 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 512.0
MMD2_k127_1552801_14 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 486.0
MMD2_k127_1552801_15 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 456.0
MMD2_k127_1552801_16 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 389.0
MMD2_k127_1552801_17 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000496 332.0
MMD2_k127_1552801_18 Class II aldolase adducin family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 307.0
MMD2_k127_1552801_19 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002295 280.0
MMD2_k127_1552801_2 Isocitrate lyase K01637 - 4.1.3.1 5.214e-227 708.0
MMD2_k127_1552801_20 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008996 248.0
MMD2_k127_1552801_21 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000002487 229.0
MMD2_k127_1552801_22 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000000000000000007908 205.0
MMD2_k127_1552801_23 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000522 181.0
MMD2_k127_1552801_24 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000009338 175.0
MMD2_k127_1552801_25 integral membrane protein K02221 - - 0.000000000000000000000000000000000000000000001869 177.0
MMD2_k127_1552801_26 Rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000001778 159.0
MMD2_k127_1552801_27 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.0000000000000000000000000000000000005884 154.0
MMD2_k127_1552801_28 Protein of unknown function (DUF805) - - - 0.00000000000000000000000000000000004953 140.0
MMD2_k127_1552801_29 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000001359 138.0
MMD2_k127_1552801_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.14e-222 699.0
MMD2_k127_1552801_30 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000001841 127.0
MMD2_k127_1552801_31 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000235 122.0
MMD2_k127_1552801_32 Belongs to the UPF0235 family K09131 - - 0.000000000000000000001565 98.0
MMD2_k127_1552801_33 Domain of unknown function (DUF4124) - - - 0.0000000007401 68.0
MMD2_k127_1552801_4 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 2.293e-209 667.0
MMD2_k127_1552801_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.005e-207 677.0
MMD2_k127_1552801_6 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 5.638e-205 657.0
MMD2_k127_1552801_7 Rod shape-determining protein MreB K03569 - - 5.135e-201 638.0
MMD2_k127_1552801_8 DNA helicase K03657 - 3.6.4.12 1.781e-197 624.0
MMD2_k127_1552801_9 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 594.0
MMD2_k127_1555420_0 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 617.0
MMD2_k127_1555420_1 Zn-dependent protease with chaperone function K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 499.0
MMD2_k127_1555420_10 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000413 82.0
MMD2_k127_1555420_2 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 485.0
MMD2_k127_1555420_3 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 312.0
MMD2_k127_1555420_4 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 285.0
MMD2_k127_1555420_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000006714 258.0
MMD2_k127_1555420_6 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000009744 241.0
MMD2_k127_1555420_7 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000004642 220.0
MMD2_k127_1555420_8 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000001959 166.0
MMD2_k127_1555420_9 - - - - 0.000000000000000000000000004529 115.0
MMD2_k127_1585044_0 heat shock protein binding - - - 1.113e-226 731.0
MMD2_k127_1585044_1 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 563.0
MMD2_k127_1585044_2 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001429 261.0
MMD2_k127_1585044_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000001391 249.0
MMD2_k127_1585044_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000001068 229.0
MMD2_k127_1585044_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000004886 48.0
MMD2_k127_1585044_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00001211 57.0
MMD2_k127_1602837_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 531.0
MMD2_k127_1602837_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 431.0
MMD2_k127_1602837_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 400.0
MMD2_k127_1602837_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 373.0
MMD2_k127_1602837_4 Methyl-accepting chemotaxis protein (MCP) signalling domain K03406,K05875 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 379.0
MMD2_k127_1602837_5 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000004014 228.0
MMD2_k127_1602837_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000001695 99.0
MMD2_k127_1603164_0 Belongs to the aldehyde dehydrogenase family K00130,K00151,K10217 GO:0003674,GO:0003824,GO:0004029,GO:0008150,GO:0008152,GO:0008802,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 2.14e-261 812.0
MMD2_k127_1603164_1 ABC-type branched-chain amino acid transport systems periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 544.0
MMD2_k127_1603164_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000001156 178.0
MMD2_k127_1603164_11 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000001368 166.0
MMD2_k127_1603164_12 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.0000000000000000000000000000000000000000001797 169.0
MMD2_k127_1603164_13 - - - - 0.0008379 49.0
MMD2_k127_1603164_2 PFAM Extradiol ring-cleavage dioxygenase class III protein subunit B K04099 - 1.13.11.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 406.0
MMD2_k127_1603164_3 transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 386.0
MMD2_k127_1603164_4 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 368.0
MMD2_k127_1603164_5 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 342.0
MMD2_k127_1603164_6 GlcNAc-PI de-N-acetylase K16515 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 349.0
MMD2_k127_1603164_7 Aldolase/RraA K02553,K10218 - 4.1.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 304.0
MMD2_k127_1603164_8 lactoylglutathione lyase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003037 255.0
MMD2_k127_1603164_9 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000528 226.0
MMD2_k127_1603825_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1328.0
MMD2_k127_1603825_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.78e-218 699.0
MMD2_k127_1603825_10 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 362.0
MMD2_k127_1603825_11 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002569 352.0
MMD2_k127_1603825_12 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001485 273.0
MMD2_k127_1603825_13 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001625 271.0
MMD2_k127_1603825_14 EVE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003792 238.0
MMD2_k127_1603825_15 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000000000000000000001143 192.0
MMD2_k127_1603825_16 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000005928 182.0
MMD2_k127_1603825_17 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000009656 184.0
MMD2_k127_1603825_18 Thioesterase - - - 0.0000000000000000000000000000000000000000000001466 171.0
MMD2_k127_1603825_19 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000006578 165.0
MMD2_k127_1603825_2 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 2.016e-214 683.0
MMD2_k127_1603825_20 cell division protein - - - 0.00000000000000000000000000000000000000127 156.0
MMD2_k127_1603825_21 DMSO reductase anchor subunit (DmsC) - - - 0.0000000000000000000000000000000000006307 151.0
MMD2_k127_1603825_22 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000005617 141.0
MMD2_k127_1603825_23 transcriptional regulator - - - 0.0000000000000000000000000000005088 136.0
MMD2_k127_1603825_24 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000001837 126.0
MMD2_k127_1603825_3 Arginyl-tRNA synthetase K01887 - 6.1.1.19 5.67e-210 668.0
MMD2_k127_1603825_4 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 2.835e-199 634.0
MMD2_k127_1603825_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 533.0
MMD2_k127_1603825_6 PFAM sulfotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 445.0
MMD2_k127_1603825_7 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 437.0
MMD2_k127_1603825_8 4Fe-4S binding domain K18362 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006802 380.0
MMD2_k127_1603825_9 Zn-dependent hydrolases including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 372.0
MMD2_k127_1610951_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 574.0
MMD2_k127_1610951_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 518.0
MMD2_k127_1610951_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 505.0
MMD2_k127_1610951_3 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 460.0
MMD2_k127_1610951_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 383.0
MMD2_k127_1610951_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000002635 114.0
MMD2_k127_1627913_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 548.0
MMD2_k127_1627913_1 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 410.0
MMD2_k127_1627913_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 336.0
MMD2_k127_1627913_3 - - - - 0.000000000000000298 91.0
MMD2_k127_1632950_0 Belongs to the glutamate synthase family - - - 6.944e-219 685.0
MMD2_k127_1632950_1 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 484.0
MMD2_k127_1632950_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 322.0
MMD2_k127_1632950_3 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000005739 193.0
MMD2_k127_1632950_4 Glyoxalase-like domain - - - 0.00000000000002913 82.0
MMD2_k127_1632950_5 - - - - 0.00000116 59.0
MMD2_k127_1650237_0 Dihydroorotate dehydrogenase K00254 - 1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 424.0
MMD2_k127_1650237_1 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 360.0
MMD2_k127_1650237_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 308.0
MMD2_k127_1650237_3 plastoquinol--plastocyanin reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
MMD2_k127_1650237_4 Ammonium Transporter Family K03320,K06580 - - 0.0000000000000000001281 89.0
MMD2_k127_1663151_0 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 469.0
MMD2_k127_1663151_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 433.0
MMD2_k127_1663151_10 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000000000000000004511 94.0
MMD2_k127_1663151_11 - - - - 0.0004408 52.0
MMD2_k127_1663151_2 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006935 454.0
MMD2_k127_1663151_3 5'-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 424.0
MMD2_k127_1663151_4 A G-specific K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 393.0
MMD2_k127_1663151_5 Peptidase family M23 K08259 - 3.4.24.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 303.0
MMD2_k127_1663151_6 Putative methyltransferase K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009836 301.0
MMD2_k127_1663151_7 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007101 269.0
MMD2_k127_1663151_8 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000002369 246.0
MMD2_k127_1663151_9 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000002934 159.0
MMD2_k127_1666603_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.42e-261 811.0
MMD2_k127_1666603_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 621.0
MMD2_k127_1666603_2 phosphate-selective porin O and P - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 476.0
MMD2_k127_1666603_3 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006886 411.0
MMD2_k127_1666603_4 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 396.0
MMD2_k127_1666603_5 Zinc-uptake complex component A periplasmic K02077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 388.0
MMD2_k127_1666603_6 membrane-bound metal-dependent K07038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 302.0
MMD2_k127_1666603_7 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001945 289.0
MMD2_k127_1666603_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007885 277.0
MMD2_k127_1677698_0 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 314.0
MMD2_k127_1677698_1 PFAM response regulator receiver K02483,K07666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 309.0
MMD2_k127_1677698_10 PIN domain K07065 - - 0.00000000000004248 79.0
MMD2_k127_1677698_2 Two-component sensor kinase N-terminal K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 293.0
MMD2_k127_1677698_3 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005008 243.0
MMD2_k127_1677698_4 Protein of unknown function (DUF1810) - - - 0.0000000000000000000000000000000000000000000000000000000000008972 213.0
MMD2_k127_1677698_5 PFAM Thioredoxin domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000007244 189.0
MMD2_k127_1677698_6 - - - - 0.00000000000000000000000000000000000000000000002326 177.0
MMD2_k127_1677698_7 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000000003355 159.0
MMD2_k127_1677698_8 PFAM Outer membrane lipoprotein Slp K07285 - - 0.00000000000000000000000000000000003705 141.0
MMD2_k127_1677698_9 Dihaem cytochrome c - - - 0.00000000000000000000000005312 119.0
MMD2_k127_1685176_0 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 436.0
MMD2_k127_1685176_1 VWA domain containing CoxE-like protein K07161 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006464 441.0
MMD2_k127_1685176_2 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 419.0
MMD2_k127_1685176_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000005887 204.0
MMD2_k127_1685176_4 dithiol-disulfide isomerase involved in polyketide biosynthesis - - - 0.000000000000000000000000000000000000000000000000002432 189.0
MMD2_k127_1685176_5 carbon monoxide dehydrogenase K09386 - - 0.00000000000000000000000000000000000000000000000001084 186.0
MMD2_k127_1688535_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 436.0
MMD2_k127_1688535_1 luciferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 347.0
MMD2_k127_1688535_2 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 328.0
MMD2_k127_1688535_3 Molybdenum cofactor synthesis domain K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006146 300.0
MMD2_k127_1688535_4 Protein tyrosine kinase K11912 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000007734 246.0
MMD2_k127_1688535_5 Belongs to the UPF0307 family K09889 - - 0.000000000000000000000000000000000000005149 151.0
MMD2_k127_1698268_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 3.839e-203 659.0
MMD2_k127_1698268_1 Carbohydrate-selective porin, OprB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 567.0
MMD2_k127_1698268_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 549.0
MMD2_k127_1698268_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 537.0
MMD2_k127_1698268_4 Fe2+ transport protein K07230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001689 270.0
MMD2_k127_1698268_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000003012 189.0
MMD2_k127_1698268_6 Cupredoxin-like domain - - - 0.0000000000000000000000000000004057 125.0
MMD2_k127_1698268_8 Hemin uptake protein hemP - - - 0.00002568 49.0
MMD2_k127_1730650_0 SpoVR like protein - - - 6.792e-237 754.0
MMD2_k127_1730650_1 Belongs to the peptidase S16 family - - - 5.361e-227 728.0
MMD2_k127_1730650_10 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 432.0
MMD2_k127_1730650_11 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 387.0
MMD2_k127_1730650_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 376.0
MMD2_k127_1730650_13 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 330.0
MMD2_k127_1730650_14 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 314.0
MMD2_k127_1730650_15 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 321.0
MMD2_k127_1730650_16 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 289.0
MMD2_k127_1730650_17 HNH endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000254 265.0
MMD2_k127_1730650_18 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009602 274.0
MMD2_k127_1730650_19 PFAM HhH-GPD family protein K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000002243 264.0
MMD2_k127_1730650_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 626.0
MMD2_k127_1730650_20 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000000001974 237.0
MMD2_k127_1730650_21 type 4 pilus biogenesis protein K02656 - - 0.00000000000000000000000000000000000000000000000000000000000003595 231.0
MMD2_k127_1730650_22 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000004366 197.0
MMD2_k127_1730650_23 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000006367 164.0
MMD2_k127_1730650_24 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000196 152.0
MMD2_k127_1730650_25 Domain of unknown function (DUF4115) K15539 - - 0.00000000000000000000000000000000000002559 156.0
MMD2_k127_1730650_26 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000003814 93.0
MMD2_k127_1730650_27 Universal stress protein family - - - 0.00000000001149 76.0
MMD2_k127_1730650_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 580.0
MMD2_k127_1730650_4 PrkA AAA domain K07180 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 563.0
MMD2_k127_1730650_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 533.0
MMD2_k127_1730650_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 512.0
MMD2_k127_1730650_7 Belongs to the UPF0229 family K09786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 458.0
MMD2_k127_1730650_8 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 439.0
MMD2_k127_1730650_9 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 432.0
MMD2_k127_1745783_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.783e-306 947.0
MMD2_k127_1745783_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 4.658e-201 633.0
MMD2_k127_1745783_10 PFAM glutaredoxin 2 - - - 0.000000000000000007734 98.0
MMD2_k127_1745783_11 PFAM Anti sigma-E protein RseA family protein K03597 - - 0.0000000000000004023 85.0
MMD2_k127_1745783_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004869 612.0
MMD2_k127_1745783_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 392.0
MMD2_k127_1745783_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 319.0
MMD2_k127_1745783_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 289.0
MMD2_k127_1745783_6 Sigma E regulatory protein, MucB RseB K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000001239 250.0
MMD2_k127_1745783_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000002129 217.0
MMD2_k127_1745783_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000004398 135.0
MMD2_k127_1745783_9 Domain of unknown function (DUF4845) - - - 0.00000000000000000000265 97.0
MMD2_k127_1752501_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1696.0
MMD2_k127_1752501_1 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 539.0
MMD2_k127_1752501_10 PFAM MAPEG family - - - 0.00000000000000000000000000000002188 144.0
MMD2_k127_1752501_11 Thioesterase superfamily K01075 - 3.1.2.23 0.00000000000000000000000007993 119.0
MMD2_k127_1752501_12 Thioesterase K01075 - 3.1.2.23 0.000000000000000000000005582 113.0
MMD2_k127_1752501_13 HNH endonuclease - - - 0.00000000000000000000002622 102.0
MMD2_k127_1752501_14 Biotin-requiring enzyme - - - 0.00000000000001901 83.0
MMD2_k127_1752501_15 DoxX K15977 - - 0.00000007294 64.0
MMD2_k127_1752501_2 Transketolase, C-terminal domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 519.0
MMD2_k127_1752501_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 522.0
MMD2_k127_1752501_4 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 458.0
MMD2_k127_1752501_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 454.0
MMD2_k127_1752501_6 Pyrogallol hydroxytransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 420.0
MMD2_k127_1752501_7 LysR substrate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 344.0
MMD2_k127_1752501_9 - - - - 0.0000000000000000000000000000000000000002967 154.0
MMD2_k127_1761767_0 COG1858 Cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 368.0
MMD2_k127_1761767_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 313.0
MMD2_k127_1761767_2 chemotaxis K03406,K03776,K05875 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 309.0
MMD2_k127_1761767_3 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000001113 240.0
MMD2_k127_1761767_4 NMT1/THI5 like - - - 0.0000000000000000000000000000000000002834 143.0
MMD2_k127_1761767_5 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000002801 123.0
MMD2_k127_1761767_6 cytochrome c K00406 - - 0.00000000000002006 85.0
MMD2_k127_1763710_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.83e-273 846.0
MMD2_k127_1763710_1 Cytochrome c oxidase, subunit K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 389.0
MMD2_k127_1763710_2 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 327.0
MMD2_k127_1763710_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 329.0
MMD2_k127_1763710_4 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000001249 134.0
MMD2_k127_1763710_5 Cbb3-type cytochrome oxidase K00407 - - 0.00000005622 57.0
MMD2_k127_1784150_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 467.0
MMD2_k127_1784150_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003837 424.0
MMD2_k127_1784150_2 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 398.0
MMD2_k127_1784150_3 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 354.0
MMD2_k127_1784150_4 Cytochrome c K08738 - - 0.000000000000000001561 85.0
MMD2_k127_1786580_0 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 516.0
MMD2_k127_1786580_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006217 327.0
MMD2_k127_1786580_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 316.0
MMD2_k127_1786580_3 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
MMD2_k127_1786580_4 universal stress protein - - - 0.000000000000000000000000000000000003695 142.0
MMD2_k127_1786580_5 DUF218 domain - - - 0.000000000000000000000000000000003676 138.0
MMD2_k127_1786580_6 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0001109 46.0
MMD2_k127_1793078_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 466.0
MMD2_k127_1793078_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 403.0
MMD2_k127_1793078_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 391.0
MMD2_k127_1793078_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 328.0
MMD2_k127_1793078_4 cysteine dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000005812 256.0
MMD2_k127_1793078_5 Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000003305 222.0
MMD2_k127_1793078_6 acyl-CoA transferases carnitine dehydratase K07749 - 2.8.3.16 0.00000000000009496 72.0
MMD2_k127_1820020_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1302.0
MMD2_k127_1820020_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 563.0
MMD2_k127_1820020_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 514.0
MMD2_k127_1820020_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 511.0
MMD2_k127_1820020_4 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 413.0
MMD2_k127_1820020_5 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 377.0
MMD2_k127_1820020_6 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000001952 164.0
MMD2_k127_1820020_7 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000008463 152.0
MMD2_k127_1820020_8 OmpA family K03286 - - 0.000000000000000000000000004634 119.0
MMD2_k127_1825085_0 Molybdopterin oxidoreductase Fe4S4 domain K00123,K22015 - 1.17.1.9,1.17.99.7 0.0 1320.0
MMD2_k127_1825085_1 Belongs to the TPP enzyme family K01577 - 4.1.1.8 3.36e-321 989.0
MMD2_k127_1825085_10 Tripartite tricarboxylate transporter TctB family - - - 0.00000000000000000000000000000000000000000008747 166.0
MMD2_k127_1825085_11 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.0000000000000000000000000000000000000008973 152.0
MMD2_k127_1825085_2 Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 6.293e-289 895.0
MMD2_k127_1825085_3 24 kD subunit K00122 - 1.17.1.9 1.167e-266 831.0
MMD2_k127_1825085_4 amp-dependent synthetase and ligase K00666 - - 1.117e-244 781.0
MMD2_k127_1825085_5 Tripartite tricarboxylate transporter TctA family K07793 - - 1.261e-241 756.0
MMD2_k127_1825085_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 488.0
MMD2_k127_1825085_7 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004481 258.0
MMD2_k127_1825085_8 Membrane protein TerC, possibly involved in tellurium resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003412 247.0
MMD2_k127_1825085_9 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000001225 223.0
MMD2_k127_1829258_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 426.0
MMD2_k127_1829258_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 321.0
MMD2_k127_1829258_2 - - - - 0.00000000000000000000000000000000000000000000000000000000006851 223.0
MMD2_k127_1835750_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2261.0
MMD2_k127_1835750_1 Domain of unknown function (DUF4445) - - - 3.957e-198 636.0
MMD2_k127_1835750_10 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.00000002647 66.0
MMD2_k127_1835750_2 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009851 581.0
MMD2_k127_1835750_3 PFAM amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 362.0
MMD2_k127_1835750_4 Pterin binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 371.0
MMD2_k127_1835750_5 Methionine synthase B12-binding module cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 306.0
MMD2_k127_1835750_6 Domain of unknown function (DUF3391) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007917 301.0
MMD2_k127_1835750_7 phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005013 281.0
MMD2_k127_1835750_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000001254 215.0
MMD2_k127_1835750_9 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000004405 79.0
MMD2_k127_1839205_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.09e-293 910.0
MMD2_k127_1839205_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 5.667e-208 654.0
MMD2_k127_1839205_10 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000009011 258.0
MMD2_k127_1839205_11 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000003135 163.0
MMD2_k127_1839205_12 LuxR family transcriptional regulator K13041 - - 0.00000000000000000000000000000000000006687 147.0
MMD2_k127_1839205_13 Pfam:DUF1049 K08992 - - 0.0000000001631 65.0
MMD2_k127_1839205_2 EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase) K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 562.0
MMD2_k127_1839205_3 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000975 552.0
MMD2_k127_1839205_4 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 525.0
MMD2_k127_1839205_5 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 489.0
MMD2_k127_1839205_6 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 462.0
MMD2_k127_1839205_7 pfkB family carbohydrate kinase K21344 - 2.7.1.167 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 384.0
MMD2_k127_1839205_8 3-5 exonuclease K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 349.0
MMD2_k127_1839205_9 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 321.0
MMD2_k127_1839680_0 Aldehyde dehydrogenase family K02618,K15514 - 1.2.1.77,1.2.1.91,3.3.2.12 1.541e-198 632.0
MMD2_k127_1839680_1 histidine kinase A domain protein K07679 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 484.0
MMD2_k127_1839680_2 chemotaxis K03406,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 450.0
MMD2_k127_1839680_3 RES - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002062 249.0
MMD2_k127_1839680_4 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000002834 237.0
MMD2_k127_1839680_5 Protein of unknown function (DUF3237) - - - 0.0000000000000000000000000000000000000000000000000002667 189.0
MMD2_k127_1839680_6 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000131 146.0
MMD2_k127_184288_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K13796 - - 8.506e-266 827.0
MMD2_k127_184288_1 FAD dependent oxidoreductase - - - 1.104e-205 646.0
MMD2_k127_184288_2 CitB domain protein K13795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 592.0
MMD2_k127_184288_3 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 359.0
MMD2_k127_184288_4 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000008814 170.0
MMD2_k127_1857627_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 502.0
MMD2_k127_1857627_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 441.0
MMD2_k127_1857627_2 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 434.0
MMD2_k127_1857627_3 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000001898 232.0
MMD2_k127_1857627_4 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000003988 216.0
MMD2_k127_1857627_5 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000000000000000000000000000000000000911 174.0
MMD2_k127_1868700_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 9.092e-217 683.0
MMD2_k127_1868700_1 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 600.0
MMD2_k127_1868700_10 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000513 109.0
MMD2_k127_1868700_11 nuclease - - - 0.00000000000000396 81.0
MMD2_k127_1868700_2 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 586.0
MMD2_k127_1868700_3 helicase superfamily c-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 482.0
MMD2_k127_1868700_4 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 364.0
MMD2_k127_1868700_5 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 347.0
MMD2_k127_1868700_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 336.0
MMD2_k127_1868700_7 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001194 276.0
MMD2_k127_1868700_8 Protein chain release factor B K15034 - - 0.0000000000000000000000000000000000000005048 153.0
MMD2_k127_1868700_9 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000004313 126.0
MMD2_k127_1879576_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 1.352e-217 692.0
MMD2_k127_1879576_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 1.664e-201 634.0
MMD2_k127_1879576_2 2,4-dienoyl-coa reductase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 576.0
MMD2_k127_1879576_3 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 450.0
MMD2_k127_1879576_4 LPPG Fo 2-phospho-L-lactate transferase K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003009 285.0
MMD2_k127_1879576_5 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000007125 237.0
MMD2_k127_1879576_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000003367 210.0
MMD2_k127_1879576_7 NIPSNAP - - - 0.00000000000000000000000000000000000000000004078 163.0
MMD2_k127_1879576_8 Cold-shock DNA-binding domain protein K03704 - - 0.00000000000000000000000000001822 119.0
MMD2_k127_1879576_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000002726 108.0
MMD2_k127_1881344_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.926e-235 733.0
MMD2_k127_1881344_1 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 309.0
MMD2_k127_1881344_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000002458 187.0
MMD2_k127_1881344_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000008431 188.0
MMD2_k127_1881344_4 PFAM ribosomal protein L31 K02909 - - 0.0000000000000000000000000001088 117.0
MMD2_k127_1881344_5 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000003409 126.0
MMD2_k127_1885230_0 AMP-binding enzyme K01897 - 6.2.1.3 2.047e-309 960.0
MMD2_k127_1885230_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 3.697e-260 818.0
MMD2_k127_1885230_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 419.0
MMD2_k127_1885230_11 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 349.0
MMD2_k127_1885230_12 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 322.0
MMD2_k127_1885230_13 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 297.0
MMD2_k127_1885230_14 hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009936 262.0
MMD2_k127_1885230_15 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000001639 215.0
MMD2_k127_1885230_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000003076 227.0
MMD2_k127_1885230_17 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000001366 223.0
MMD2_k127_1885230_18 binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000001186 212.0
MMD2_k127_1885230_19 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000001453 162.0
MMD2_k127_1885230_2 Biotin carboxylase C-terminal domain K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 5.643e-235 747.0
MMD2_k127_1885230_20 ACT domain - - - 0.00000000000000000000000000000001775 132.0
MMD2_k127_1885230_21 LTXXQ motif family protein - - - 0.00000000000000001646 89.0
MMD2_k127_1885230_22 Protein of unknown function (DUF1289) K06938 - - 0.0000000005745 71.0
MMD2_k127_1885230_3 Periplasmic binding protein K01999 - - 7.705e-204 645.0
MMD2_k127_1885230_4 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 530.0
MMD2_k127_1885230_5 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 505.0
MMD2_k127_1885230_6 Histidine kinase K05962 - 2.7.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 462.0
MMD2_k127_1885230_7 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 435.0
MMD2_k127_1885230_8 PFAM ABC transporter related K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 426.0
MMD2_k127_1885230_9 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 426.0
MMD2_k127_1903428_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 552.0
MMD2_k127_1903428_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 482.0
MMD2_k127_1903428_2 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 302.0
MMD2_k127_1903428_3 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000007834 217.0
MMD2_k127_1904340_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1341.0
MMD2_k127_1904340_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 335.0
MMD2_k127_1904340_2 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000181 238.0
MMD2_k127_1904340_3 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000001335 212.0
MMD2_k127_1904340_4 ABC-2 family transporter protein K09694 - - 0.00000000000000000000000000000000000000000002792 175.0
MMD2_k127_1904340_5 Protein of unknown function DUF45 K07043 - - 0.000000000000000000000000000000000000000002859 161.0
MMD2_k127_1912746_0 Sugar (and other) transporter K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009357 586.0
MMD2_k127_1912746_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006277 281.0
MMD2_k127_1912746_2 Glutathione S-transferase, N-terminal domain K01800 - 5.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001008 262.0
MMD2_k127_1912746_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000002421 176.0
MMD2_k127_1922404_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01577,K01652,K03852 - 2.2.1.6,2.3.3.15,4.1.1.8 0.0 1095.0
MMD2_k127_1922404_1 belongs to the aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 7.913e-218 692.0
MMD2_k127_1922404_2 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 571.0
MMD2_k127_1922404_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000404 377.0
MMD2_k127_1922404_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000003096 204.0
MMD2_k127_1922404_5 FAD dependent oxidoreductase - - - 0.0000000000002633 73.0
MMD2_k127_1922977_0 Amidohydrolase family - - - 1.594e-216 683.0
MMD2_k127_1922977_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.223e-214 693.0
MMD2_k127_1922977_10 glyoxalase K07032 - - 0.000000000000000000000000000000000000000000000000000000000000000000005452 235.0
MMD2_k127_1922977_11 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000003707 194.0
MMD2_k127_1922977_12 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000000000000797 197.0
MMD2_k127_1922977_13 CRP FNR family K21563 - - 0.0000000000000000000000000000000000000000001758 171.0
MMD2_k127_1922977_14 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000000000000000000000000000000019 145.0
MMD2_k127_1922977_15 Uncharacterized protein conserved in bacteria (DUF2147) - - - 0.000000000000000000000000000000000003514 147.0
MMD2_k127_1922977_16 Phosphate-starvation-inducible E - - - 0.000000000000000000000000000000000007378 141.0
MMD2_k127_1922977_17 Invasion gene expression up-regulator SirB - - - 0.00000000000000000000000000000000002057 140.0
MMD2_k127_1922977_18 heat shock protein DnaJ K05516 - - 0.0000000000000000000000000000000004052 134.0
MMD2_k127_1922977_19 Universal stress protein - - - 0.000000000000000000000000000000003941 133.0
MMD2_k127_1922977_2 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 551.0
MMD2_k127_1922977_20 MAPEG family - - - 0.0000000000000000000000000000001708 127.0
MMD2_k127_1922977_21 - - - - 0.0000000000000000000000000000009978 123.0
MMD2_k127_1922977_22 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000001307 114.0
MMD2_k127_1922977_23 Belongs to the universal stress protein A family - - - 0.000000000000000000000001036 109.0
MMD2_k127_1922977_24 protein conserved in bacteria K09937 - - 0.00000000000000000001698 91.0
MMD2_k127_1922977_25 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000013 91.0
MMD2_k127_1922977_26 Heavy metal transport detoxification protein K07213 - - 0.0000000000000003463 79.0
MMD2_k127_1922977_3 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 505.0
MMD2_k127_1922977_4 Integral membrane protein TerC family K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004223 460.0
MMD2_k127_1922977_5 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 446.0
MMD2_k127_1922977_6 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 433.0
MMD2_k127_1922977_7 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 425.0
MMD2_k127_1922977_8 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006175 383.0
MMD2_k127_1922977_9 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009853 393.0
MMD2_k127_1928503_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.024e-283 880.0
MMD2_k127_1928503_1 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.09e-252 797.0
MMD2_k127_1928503_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 541.0
MMD2_k127_1928503_3 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 356.0
MMD2_k127_1928503_4 Transcriptional regulatory protein, C terminal K02483,K07666,K07774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 334.0
MMD2_k127_1928503_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 353.0
MMD2_k127_1928503_6 RecG wedge domain K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000004228 223.0
MMD2_k127_1928503_7 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.000000000000000000000000000000000000000000000009538 172.0
MMD2_k127_194637_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.698e-255 800.0
MMD2_k127_194637_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.168e-211 663.0
MMD2_k127_194637_2 ribosomal rna small subunit methyltransferase - - - 3.808e-201 638.0
MMD2_k127_194637_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009709 451.0
MMD2_k127_194637_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 299.0
MMD2_k127_194637_5 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000004869 243.0
MMD2_k127_194637_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000001152 211.0
MMD2_k127_194637_7 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000009636 144.0
MMD2_k127_203375_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 460.0
MMD2_k127_203375_1 PFAM MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 308.0
MMD2_k127_203375_2 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000005264 220.0
MMD2_k127_203375_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000003461 206.0
MMD2_k127_203375_4 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB K03559 - - 0.00000000000000000000000000000000004726 149.0
MMD2_k127_203375_5 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB K03559 - - 0.00000000000000000000000000000004324 136.0
MMD2_k127_203375_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000000000000000000000001051 126.0
MMD2_k127_2079449_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 459.0
MMD2_k127_2079449_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 356.0
MMD2_k127_2079449_2 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005692 282.0
MMD2_k127_2079449_3 Belongs to the CinA family K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000000000002194 188.0
MMD2_k127_2079449_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000001727 185.0
MMD2_k127_2079449_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000007075 154.0
MMD2_k127_2079449_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000005923 138.0
MMD2_k127_2098986_0 TIGRFAM L-lactate transport K03303 - - 6.849e-282 876.0
MMD2_k127_2098986_1 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 454.0
MMD2_k127_2098986_10 ECF sigma factor K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002109 263.0
MMD2_k127_2098986_11 - - - - 0.000000000000000000000000000000000000000000002826 181.0
MMD2_k127_2098986_12 HxlR-like helix-turn-helix - - - 0.0000000000000000000000000000000000000004625 153.0
MMD2_k127_2098986_13 - - - - 0.00000000000000000001764 94.0
MMD2_k127_2098986_14 peptidyl-tyrosine sulfation K08372 - - 0.0000000000003218 82.0
MMD2_k127_2098986_2 Feruloyl esterase K21105 - 3.1.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 442.0
MMD2_k127_2098986_3 Protein of unknown function (DUF1800) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 428.0
MMD2_k127_2098986_4 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 411.0
MMD2_k127_2098986_5 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 394.0
MMD2_k127_2098986_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 317.0
MMD2_k127_2098986_7 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 300.0
MMD2_k127_2098986_8 methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002921 276.0
MMD2_k127_2098986_9 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006728 285.0
MMD2_k127_2105071_0 Major Facilitator Superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 569.0
MMD2_k127_2105071_1 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 436.0
MMD2_k127_2105071_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 311.0
MMD2_k127_2105071_3 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 298.0
MMD2_k127_2105071_4 FAD binding domain K00481 GO:0000166,GO:0003674,GO:0003824,GO:0004497,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016705,GO:0016709,GO:0018659,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.14.13.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004936 263.0
MMD2_k127_2105071_5 peptidylprolyl isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000001006 258.0
MMD2_k127_2105071_6 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002238 248.0
MMD2_k127_2105071_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000004062 213.0
MMD2_k127_2105071_8 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000008512 207.0
MMD2_k127_2105071_9 Belongs to the BolA IbaG family K05527 - - 0.0000000000000000000001321 108.0
MMD2_k127_2107839_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 625.0
MMD2_k127_2107839_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 429.0
MMD2_k127_2107839_2 Bacterial DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 335.0
MMD2_k127_2107839_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000002606 112.0
MMD2_k127_2107839_4 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.0000000000000000007238 101.0
MMD2_k127_2170216_0 AMP-binding enzyme C-terminal domain K00666 - - 1.532e-269 850.0
MMD2_k127_2170216_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 546.0
MMD2_k127_2170216_10 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000000000000000000005547 220.0
MMD2_k127_2170216_11 Transcriptional regulator, Crp Fnr family K21563 - - 0.0000000000000000000000000000000000000000000000000001291 194.0
MMD2_k127_2170216_12 deoxyhypusine monooxygenase activity K01387 - 3.4.24.3 0.00000000000000000000000000000000007408 152.0
MMD2_k127_2170216_13 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.0000000000000002133 87.0
MMD2_k127_2170216_14 Histidine kinase - - - 0.00000001602 67.0
MMD2_k127_2170216_2 Histidine kinase K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 370.0
MMD2_k127_2170216_3 glycosyl - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 335.0
MMD2_k127_2170216_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 325.0
MMD2_k127_2170216_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 299.0
MMD2_k127_2170216_6 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 292.0
MMD2_k127_2170216_7 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001616 282.0
MMD2_k127_2170216_8 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration - - - 0.00000000000000000000000000000000000000000000000000000000000000000001024 240.0
MMD2_k127_2170216_9 Formylmethanofuran dehydrogenase, subunit e - - - 0.00000000000000000000000000000000000000000000000000000000000002421 221.0
MMD2_k127_2213794_0 Fumarate reductase flavoprotein C-term - - - 1.536e-250 785.0
MMD2_k127_2213794_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 433.0
MMD2_k127_2213794_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 397.0
MMD2_k127_2213794_3 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 398.0
MMD2_k127_2213794_4 2Fe-2S iron-sulfur cluster binding domain - - - 0.00002212 57.0
MMD2_k127_2215764_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.081e-211 668.0
MMD2_k127_2215764_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 456.0
MMD2_k127_2215764_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005815 459.0
MMD2_k127_2215764_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 387.0
MMD2_k127_2215764_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 352.0
MMD2_k127_2215764_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 355.0
MMD2_k127_2215764_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007898 269.0
MMD2_k127_2215764_7 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000001882 203.0
MMD2_k127_2215764_8 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000003457 121.0
MMD2_k127_2223301_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 394.0
MMD2_k127_2223301_1 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 368.0
MMD2_k127_2223301_2 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000447 279.0
MMD2_k127_2223301_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002833 226.0
MMD2_k127_2223301_4 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000001616 196.0
MMD2_k127_2223301_5 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.0000000000000000000000000000000000000000000000000002285 191.0
MMD2_k127_2223301_6 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000001159 162.0
MMD2_k127_2223301_7 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000002315 86.0
MMD2_k127_2223301_8 Bacterial protein of unknown function (DUF883) - - - 0.00000000000004102 76.0
MMD2_k127_2316195_0 MASE1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 336.0
MMD2_k127_2316195_1 Flagellar regulatory protein FleQ - - - 0.00000000000000000000000000000000000000000000000000000000455 205.0
MMD2_k127_2316195_2 Aminotransferase class I and II K09758 - 4.1.1.12 0.000000000000000000000000000000000000000000000001294 179.0
MMD2_k127_2316195_3 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000008272 148.0
MMD2_k127_2316195_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000199 116.0
MMD2_k127_2316195_5 - - - - 0.00000000000000009813 85.0
MMD2_k127_2316195_6 - - - - 0.000000002536 63.0
MMD2_k127_2328006_0 protein synthesis factor, GTP-binding K06207 - - 1.271e-294 915.0
MMD2_k127_2328006_1 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 9.006e-234 732.0
MMD2_k127_2328006_10 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000006946 86.0
MMD2_k127_2328006_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 581.0
MMD2_k127_2328006_3 Fatty acid desaturase K00496 GO:0003674,GO:0003824,GO:0004497,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016713,GO:0018685,GO:0043446,GO:0043448,GO:0044237,GO:0044248,GO:0055114,GO:0071704,GO:1901575 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 496.0
MMD2_k127_2328006_4 Short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 374.0
MMD2_k127_2328006_5 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
MMD2_k127_2328006_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002009 273.0
MMD2_k127_2328006_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000000004625 243.0
MMD2_k127_2328006_8 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000102 232.0
MMD2_k127_2328006_9 pdz dhr glgf - - - 0.00000000000000000000000000000000000002433 165.0
MMD2_k127_2328636_0 Domain of unknown function (DUF4105) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 604.0
MMD2_k127_2328636_1 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 535.0
MMD2_k127_2328636_10 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000000000000000007861 177.0
MMD2_k127_2328636_11 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000000009829 171.0
MMD2_k127_2328636_12 - - - - 0.000000000000000000000000000000001566 135.0
MMD2_k127_2328636_13 Cas6 Crispr - - - 0.0000000000000000000000001605 114.0
MMD2_k127_2328636_14 - - - - 0.00000000000000000000003152 100.0
MMD2_k127_2328636_15 - - - - 0.0000000000000000003835 89.0
MMD2_k127_2328636_16 cyclopropane-fatty-acyl-phospholipid synthase K05928 - 2.1.1.95 0.00000000004441 74.0
MMD2_k127_2328636_17 OmpA family - - - 0.0000002637 54.0
MMD2_k127_2328636_2 PFAM von Willebrand factor type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 531.0
MMD2_k127_2328636_3 PFAM Methylated-DNA- protein -cysteine S-methyltransferase, DNA binding K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 474.0
MMD2_k127_2328636_4 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 434.0
MMD2_k127_2328636_5 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 393.0
MMD2_k127_2328636_6 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 338.0
MMD2_k127_2328636_7 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 317.0
MMD2_k127_2328636_8 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000006998 242.0
MMD2_k127_2328636_9 - - - - 0.00000000000000000000000000000000000000000000000000000000001625 220.0
MMD2_k127_2357133_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1240.0
MMD2_k127_2357133_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.02e-246 773.0
MMD2_k127_2357133_10 phytoene K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 339.0
MMD2_k127_2357133_11 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005884 280.0
MMD2_k127_2357133_12 Acyl-transferase - - - 0.00000000000000000000000000000000000000000000006611 182.0
MMD2_k127_2357133_13 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000000000003617 132.0
MMD2_k127_2357133_14 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000006257 123.0
MMD2_k127_2357133_16 - - - - 0.00000001311 61.0
MMD2_k127_2357133_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 4.006e-218 682.0
MMD2_k127_2357133_3 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 534.0
MMD2_k127_2357133_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 476.0
MMD2_k127_2357133_5 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 475.0
MMD2_k127_2357133_6 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 398.0
MMD2_k127_2357133_7 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 363.0
MMD2_k127_2357133_8 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 358.0
MMD2_k127_2357133_9 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 362.0
MMD2_k127_2362401_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 407.0
MMD2_k127_2362401_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 400.0
MMD2_k127_2362401_10 STAS domain K07122 - - 0.0000000001373 73.0
MMD2_k127_2362401_2 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 396.0
MMD2_k127_2362401_3 ATPases associated with a variety of cellular activities K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009574 353.0
MMD2_k127_2362401_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 350.0
MMD2_k127_2362401_5 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001544 275.0
MMD2_k127_2362401_6 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000000000000000000000003535 218.0
MMD2_k127_2362401_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000184 214.0
MMD2_k127_2362401_8 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000003951 214.0
MMD2_k127_2362401_9 Belongs to the BolA IbaG family - - - 0.0000000000000000000000004976 117.0
MMD2_k127_2376640_0 AMP-binding enzyme K01895 - 6.2.1.1 3.526e-232 731.0
MMD2_k127_2376640_1 Ammonium Transporter Family K03320,K06580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 591.0
MMD2_k127_2376640_2 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002459 293.0
MMD2_k127_2376640_3 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003997 267.0
MMD2_k127_2376640_4 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000007131 227.0
MMD2_k127_2376640_5 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000001709 209.0
MMD2_k127_2376640_6 Type IX secretion system membrane protein PorP/SprF - - - 0.00000000000000000000000000000000000000000002107 178.0
MMD2_k127_2422721_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 434.0
MMD2_k127_2422721_1 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 392.0
MMD2_k127_2422721_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000008564 231.0
MMD2_k127_2422721_3 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000101 198.0
MMD2_k127_2456820_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 599.0
MMD2_k127_2456820_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 445.0
MMD2_k127_2456820_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 428.0
MMD2_k127_2456820_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 370.0
MMD2_k127_2456820_4 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 327.0
MMD2_k127_2456820_5 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 326.0
MMD2_k127_2456820_6 Thioesterase superfamily protein - - - 0.000000000000000000000002751 115.0
MMD2_k127_2456820_7 membrane transporter protein K07090 - - 0.0000000000000002878 83.0
MMD2_k127_251693_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.737e-286 887.0
MMD2_k127_251693_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 2.694e-219 687.0
MMD2_k127_251693_2 homoserine dehydrogenase - - - 1.137e-209 659.0
MMD2_k127_251693_3 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 448.0
MMD2_k127_251693_4 chemotaxis K03406,K03776,K05874 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 327.0
MMD2_k127_251693_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.00000000000000000000000000368 127.0
MMD2_k127_251693_6 PBP superfamily domain K02040 - - 0.0000000000000000000000002441 116.0
MMD2_k127_2535851_0 Putative diguanylate phosphodiesterase - - - 3.535e-203 685.0
MMD2_k127_2535851_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002003 244.0
MMD2_k127_2535851_2 PFAM MaoC domain protein dehydratase - - - 0.000000000000000000000000000000000000000000000001195 184.0
MMD2_k127_2535851_3 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000006375 143.0
MMD2_k127_2535851_4 - - - - 0.0000000000000000003347 102.0
MMD2_k127_2596873_0 7TM diverse intracellular signalling - - - 2.974e-300 952.0
MMD2_k127_2596873_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 552.0
MMD2_k127_2596873_10 Catalyzes the conversion of feruloyl-CoA to vanillin and acetyl-CoA K18383 - 4.1.2.41,4.2.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 357.0
MMD2_k127_2596873_11 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 374.0
MMD2_k127_2596873_12 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 349.0
MMD2_k127_2596873_13 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 324.0
MMD2_k127_2596873_14 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 291.0
MMD2_k127_2596873_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K03793 - 1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000251 302.0
MMD2_k127_2596873_16 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002797 285.0
MMD2_k127_2596873_17 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006391 279.0
MMD2_k127_2596873_18 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002451 271.0
MMD2_k127_2596873_19 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001001 289.0
MMD2_k127_2596873_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 523.0
MMD2_k127_2596873_20 Peptidase C13 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005026 269.0
MMD2_k127_2596873_21 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000003841 222.0
MMD2_k127_2596873_22 - - - - 0.0000000000000000000000000000000000000000000000000000000000001776 234.0
MMD2_k127_2596873_23 Protein of unknown function (DUF2905) - - - 0.00000000000002643 75.0
MMD2_k127_2596873_24 membrane K08985 - - 0.00002784 57.0
MMD2_k127_2596873_3 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 496.0
MMD2_k127_2596873_4 PFAM cyclase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 468.0
MMD2_k127_2596873_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 409.0
MMD2_k127_2596873_6 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 415.0
MMD2_k127_2596873_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 428.0
MMD2_k127_2596873_8 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 415.0
MMD2_k127_2596873_9 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 379.0
MMD2_k127_2608657_0 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 524.0
MMD2_k127_2608657_1 NMT1/THI5 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 506.0
MMD2_k127_2608657_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 342.0
MMD2_k127_2608657_3 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000002928 252.0
MMD2_k127_2645852_0 cytochrome - - - 1.457e-234 752.0
MMD2_k127_2645852_1 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 559.0
MMD2_k127_2645852_2 Peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 505.0
MMD2_k127_2645852_3 Peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 359.0
MMD2_k127_2645852_4 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007588 265.0
MMD2_k127_2645852_5 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002666 269.0
MMD2_k127_2645852_6 lipid carrier protein - - - 0.00000000000000000000000000000000001768 141.0
MMD2_k127_2645852_7 Class ii aldolase K01628 - 4.1.2.17 0.000000000000000000000000000001371 130.0
MMD2_k127_2655288_0 His Kinase A (phospho-acceptor) domain - - - 0.0 1126.0
MMD2_k127_2655288_1 Sugar (and other) transporter - - - 4.391e-251 785.0
MMD2_k127_2655288_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 464.0
MMD2_k127_2655288_3 peroxidase K07223 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 393.0
MMD2_k127_2655288_4 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 287.0
MMD2_k127_2655288_5 PFAM Metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000978 243.0
MMD2_k127_2655288_6 - - - - 0.0000000000006263 73.0
MMD2_k127_2655288_8 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0001277 49.0
MMD2_k127_2703885_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 2.334e-230 728.0
MMD2_k127_2703885_1 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 407.0
MMD2_k127_2703885_2 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 314.0
MMD2_k127_2703885_3 - - - - 0.00000000000000000000000000000000000000000000000000000144 211.0
MMD2_k127_2703885_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000002575 174.0
MMD2_k127_2703885_5 - - - - 0.00004316 54.0
MMD2_k127_2778362_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.286e-199 630.0
MMD2_k127_2778362_1 phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 454.0
MMD2_k127_2778362_10 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000001373 176.0
MMD2_k127_2778362_11 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000000000002442 160.0
MMD2_k127_2778362_12 - - - - 0.0001023 50.0
MMD2_k127_2778362_2 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 438.0
MMD2_k127_2778362_3 membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 407.0
MMD2_k127_2778362_4 Mg2 and Co2 transporter CorC K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 379.0
MMD2_k127_2778362_5 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 360.0
MMD2_k127_2778362_6 Ubiquinone biosynthesis hydroxylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 359.0
MMD2_k127_2778362_7 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003093 352.0
MMD2_k127_2778362_8 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000007958 210.0
MMD2_k127_2778362_9 ApaG domain K06195 - - 0.00000000000000000000000000000000000000000000000000000001301 199.0
MMD2_k127_284562_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 6.073e-295 925.0
MMD2_k127_284562_1 metal-dependent hydrolase of the TIM-barrel fold K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 527.0
MMD2_k127_284562_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 518.0
MMD2_k127_284562_3 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 500.0
MMD2_k127_284562_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 304.0
MMD2_k127_284562_5 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003153 275.0
MMD2_k127_284562_6 PFAM regulatory protein MerR - - - 0.000000000000000000000000000000000000000000000001172 177.0
MMD2_k127_284562_7 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000007775 169.0
MMD2_k127_284562_8 Belongs to the binding-protein-dependent transport system permease family - - - 0.00000000000000000005229 92.0
MMD2_k127_284562_9 dehydrogenase - - - 0.0001078 46.0
MMD2_k127_285929_0 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 481.0
MMD2_k127_285929_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 376.0
MMD2_k127_285929_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000004467 113.0
MMD2_k127_285929_11 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000005569 108.0
MMD2_k127_285929_12 biosynthesis protein K03328 - - 0.0000001716 61.0
MMD2_k127_285929_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 361.0
MMD2_k127_285929_3 PFAM amidohydrolase 2 K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 337.0
MMD2_k127_285929_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 325.0
MMD2_k127_285929_5 HlyD family K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000999 289.0
MMD2_k127_285929_6 ATPases associated with a variety of cellular activities K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003694 289.0
MMD2_k127_285929_7 Hsp33 protein K04083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004359 258.0
MMD2_k127_285929_8 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000006672 242.0
MMD2_k127_285929_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000006099 226.0
MMD2_k127_2865088_0 dna topoisomerase III K03169 - 5.99.1.2 0.0 1115.0
MMD2_k127_2865088_1 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 373.0
MMD2_k127_2865088_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 318.0
MMD2_k127_2865088_3 PFAM Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000805 236.0
MMD2_k127_2871378_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 1.196e-202 641.0
MMD2_k127_2871378_1 histidine kinase, dimerisation and phosphoacceptor region K02486 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 306.0
MMD2_k127_2871378_2 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000002746 242.0
MMD2_k127_2871378_3 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000001554 81.0
MMD2_k127_2875939_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2343.0
MMD2_k127_2875939_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 4.986e-265 829.0
MMD2_k127_2875939_10 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 554.0
MMD2_k127_2875939_11 Zinc-binding dehydrogenase K07538 - 1.1.1.368 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 500.0
MMD2_k127_2875939_12 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 454.0
MMD2_k127_2875939_13 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 424.0
MMD2_k127_2875939_14 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 369.0
MMD2_k127_2875939_15 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 328.0
MMD2_k127_2875939_16 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000002973 254.0
MMD2_k127_2875939_17 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000306 237.0
MMD2_k127_2875939_18 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000004253 223.0
MMD2_k127_2875939_19 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000111 211.0
MMD2_k127_2875939_2 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.25e-238 745.0
MMD2_k127_2875939_20 fimbrial biogenesis protein PilN K02663 - - 0.000000000000000000000000000000000000000000000000000005006 196.0
MMD2_k127_2875939_21 translation initiation inhibitor, yjgF family - - - 0.00000000000000000000000000000000000000000000001989 175.0
MMD2_k127_2875939_22 DMSO reductase anchor subunit (DmsC) K18363 - - 0.00000000000000000000000000000000000000000007189 168.0
MMD2_k127_2875939_23 pilus assembly protein PilP K02665 - - 0.00000000000000000000000000000000000003184 152.0
MMD2_k127_2875939_24 ferredoxin - - - 0.00000000000000000000000000000000000009567 144.0
MMD2_k127_2875939_25 Rubrerythrin - - - 0.00000000000000000000000000000007761 141.0
MMD2_k127_2875939_26 OmpA-like transmembrane domain K03286 - - 0.000000006076 65.0
MMD2_k127_2875939_3 type II and III secretion system protein K02666 - - 1.726e-235 748.0
MMD2_k127_2875939_4 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 5.931e-219 693.0
MMD2_k127_2875939_5 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 9.081e-201 654.0
MMD2_k127_2875939_6 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 603.0
MMD2_k127_2875939_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 588.0
MMD2_k127_2875939_8 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 560.0
MMD2_k127_2875939_9 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 571.0
MMD2_k127_2898202_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 6.633e-317 976.0
MMD2_k127_2898202_1 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 1.19e-264 831.0
MMD2_k127_2898202_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001026 257.0
MMD2_k127_2898202_11 Acetolactate synthase small K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000002241 256.0
MMD2_k127_2898202_12 Sugar (and other) transporter K07552 - - 0.00000000000000000000000000000000000000000000000000000000000000001145 241.0
MMD2_k127_2898202_13 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000001714 191.0
MMD2_k127_2898202_14 RDD family - - - 0.0000000000000000000000002702 118.0
MMD2_k127_2898202_15 Protein of unknown function (DUF3106) - - - 0.000000000000000000005542 104.0
MMD2_k127_2898202_16 Protein of unknown function (DUF3619) - - - 0.00000000000000953 79.0
MMD2_k127_2898202_2 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 605.0
MMD2_k127_2898202_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 586.0
MMD2_k127_2898202_4 Oxidoreductase, FAD-binding family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 476.0
MMD2_k127_2898202_5 C-terminal AAA-associated domain K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008469 496.0
MMD2_k127_2898202_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 351.0
MMD2_k127_2898202_7 protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 319.0
MMD2_k127_2898202_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007482 306.0
MMD2_k127_2898202_9 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000419 282.0
MMD2_k127_2899422_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.168e-289 899.0
MMD2_k127_2899422_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.26e-199 634.0
MMD2_k127_2899422_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 597.0
MMD2_k127_2899422_3 Amidase K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 493.0
MMD2_k127_2899422_4 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 416.0
MMD2_k127_2899422_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 407.0
MMD2_k127_2899422_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 331.0
MMD2_k127_2899422_7 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000002888 235.0
MMD2_k127_2899422_8 PFAM ATP-binding region, ATPase domain protein - - - 0.0001414 46.0
MMD2_k127_2936025_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008565 586.0
MMD2_k127_2936025_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 527.0
MMD2_k127_2936025_2 Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 405.0
MMD2_k127_2936025_3 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 405.0
MMD2_k127_2936025_4 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008556 384.0
MMD2_k127_2936025_5 Iron-sulphur cluster biosynthesis K15724 - - 0.000000000000000000000000000000000000000000000000000000000000302 214.0
MMD2_k127_2936025_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000006875 209.0
MMD2_k127_2936025_7 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000007796 174.0
MMD2_k127_2936025_8 - - - - 0.0000000000000000000000000000000000000000001822 179.0
MMD2_k127_3003401_0 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 2.53e-255 794.0
MMD2_k127_3003401_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 512.0
MMD2_k127_3003401_2 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005006 419.0
MMD2_k127_3003401_3 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 413.0
MMD2_k127_3003401_4 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 368.0
MMD2_k127_3003401_5 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000001573 194.0
MMD2_k127_3003401_6 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000001321 201.0
MMD2_k127_3003401_7 Domain of unknown function (DUF4124) - - - 0.000000000000000005524 91.0
MMD2_k127_3005257_0 Cupredoxin-like domain K00376 - 1.7.2.4 0.0 1016.0
MMD2_k127_3005257_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 482.0
MMD2_k127_3005257_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 398.0
MMD2_k127_3005257_3 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 338.0
MMD2_k127_3005257_4 Protein of unknown function (DUF3305) - - - 0.000000000000000000000000000000000000006925 150.0
MMD2_k127_3005257_5 Protein of unknown function (DUF3306) - - - 0.000000000000000000002974 105.0
MMD2_k127_3005257_6 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.0000000001611 75.0
MMD2_k127_302067_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 563.0
MMD2_k127_302067_1 protein involved in outer membrane biogenesis K07290 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0032386,GO:0032879,GO:0032880,GO:0033157,GO:0044464,GO:0050789,GO:0051049,GO:0051223,GO:0060341,GO:0065007,GO:0070201,GO:0071944,GO:0090087,GO:0090313,GO:1903533,GO:1903827,GO:1905475 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 457.0
MMD2_k127_302067_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005391 259.0
MMD2_k127_302067_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 251.0
MMD2_k127_302067_4 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000000000000009772 220.0
MMD2_k127_302067_5 Heavy-metal resistance - - - 0.000000000000000000000000000000000004556 142.0
MMD2_k127_302067_6 - - - - 0.00000000000000000000000000000000006782 139.0
MMD2_k127_302067_7 AntiSigma factor - - - 0.00000000000000000003594 97.0
MMD2_k127_302067_8 - - - - 0.00000000000001861 78.0
MMD2_k127_3022928_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 328.0
MMD2_k127_3022928_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002306 276.0
MMD2_k127_3022928_10 cyclic nucleotide-binding - - - 0.00000003729 66.0
MMD2_k127_3022928_2 XdhC Rossmann domain K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001212 253.0
MMD2_k127_3022928_3 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000002874 240.0
MMD2_k127_3022928_4 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000001799 224.0
MMD2_k127_3022928_5 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000002722 169.0
MMD2_k127_3022928_6 COG0822 NifU homolog involved in Fe-S cluster formation - - - 0.000000000000000000000000000000000002998 153.0
MMD2_k127_3022928_7 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000000000000002594 146.0
MMD2_k127_3022928_8 - - - - 0.0000000000000000000000000008425 119.0
MMD2_k127_3022928_9 cyclic nucleotide binding K10914 - - 0.000000002993 69.0
MMD2_k127_3076170_0 Single-stranded-DNA-specific exonuclease K07462 - - 4.051e-215 687.0
MMD2_k127_3076170_1 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 350.0
MMD2_k127_3076170_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 331.0
MMD2_k127_3076170_3 DNA repair - GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0036260,GO:0036261,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071164,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000005625 180.0
MMD2_k127_3076170_4 KTSC domain - - - 0.00000001304 59.0
MMD2_k127_3076170_5 Evidence 4 Homologs of previously reported genes of - - - 0.00000004805 58.0
MMD2_k127_308403_0 FMN_bind - - - 0.0 1029.0
MMD2_k127_308403_1 Periplasmic copper-binding protein (NosD) K07218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 603.0
MMD2_k127_308403_2 COG1131 ABC-type multidrug transport system, ATPase component K19340 - - 0.000000000000000000000000000000000000000001445 158.0
MMD2_k127_308403_3 domain, Protein - - - 0.00000000000000000000000000000000000005483 147.0
MMD2_k127_308403_4 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.0000000000000000002808 92.0
MMD2_k127_309384_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 5.028e-228 716.0
MMD2_k127_309384_1 Belongs to the GARS family K01945 - 6.3.4.13 3.916e-194 614.0
MMD2_k127_309384_10 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 257.0
MMD2_k127_309384_11 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002687 255.0
MMD2_k127_309384_12 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002032 256.0
MMD2_k127_309384_13 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000003414 110.0
MMD2_k127_309384_14 - - - - 0.0000000000000000003857 94.0
MMD2_k127_309384_15 - - - - 0.0000000000004187 73.0
MMD2_k127_309384_16 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000001513 68.0
MMD2_k127_309384_2 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 605.0
MMD2_k127_309384_3 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 544.0
MMD2_k127_309384_4 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 436.0
MMD2_k127_309384_5 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 410.0
MMD2_k127_309384_6 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 441.0
MMD2_k127_309384_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 403.0
MMD2_k127_309384_8 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 304.0
MMD2_k127_309384_9 FAD binding domain K03185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000174 282.0
MMD2_k127_3117330_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 465.0
MMD2_k127_3117330_1 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 341.0
MMD2_k127_3117330_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000003016 280.0
MMD2_k127_3117330_3 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000006374 227.0
MMD2_k127_3117330_4 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.00000000000000000000000000000000000000000000000001295 183.0
MMD2_k127_3117330_5 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000000000000001362 151.0
MMD2_k127_3117330_6 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000000000000000000000000001553 145.0
MMD2_k127_3117330_7 Carbon monoxide dehydrogenase subunit G (CoxG) - - - 0.00000000000000000000000000000001132 137.0
MMD2_k127_3147945_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.457e-211 664.0
MMD2_k127_3147945_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 389.0
MMD2_k127_3147945_2 COG1024 Enoyl-CoA hydratase carnithine racemase K15866 GO:0003674,GO:0003824,GO:0004300,GO:0005488,GO:0005515,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006725,GO:0006805,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009404,GO:0009407,GO:0009410,GO:0009636,GO:0009850,GO:0009852,GO:0009987,GO:0010124,GO:0010817,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0019395,GO:0019439,GO:0019748,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0042178,GO:0042221,GO:0042445,GO:0042447,GO:0042537,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071466,GO:0071704,GO:0072329,GO:0098754,GO:1901360,GO:1901361,GO:1901575 5.3.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 348.0
MMD2_k127_3147945_3 Four helix bundle sensory module for signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003825 310.0
MMD2_k127_3147945_4 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000009594 223.0
MMD2_k127_3147945_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000003786 177.0
MMD2_k127_3147945_6 Catalyzes the formation of trans-2- enoyl-CoA from 2,4-dienoyl-CoA K00219 - 1.3.1.34 0.0000000000000000000002298 99.0
MMD2_k127_3152718_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.367e-199 628.0
MMD2_k127_3152718_1 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 508.0
MMD2_k127_3152718_10 - - - - 0.000000000000000000000000000002097 134.0
MMD2_k127_3152718_11 Protein of unknown function (DUF1499) - - - 0.0000000000000000000676 93.0
MMD2_k127_3152718_12 Protein of unknown function (DUF465) - - - 0.000000000008643 72.0
MMD2_k127_3152718_2 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 359.0
MMD2_k127_3152718_3 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 293.0
MMD2_k127_3152718_4 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000005883 263.0
MMD2_k127_3152718_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001449 274.0
MMD2_k127_3152718_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000633 245.0
MMD2_k127_3152718_7 Thioesterase superfamily protein K10806 - - 0.0000000000000000000000000000000000000000000000000002772 187.0
MMD2_k127_3152718_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000000008685 190.0
MMD2_k127_3152718_9 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000001256 169.0
MMD2_k127_3167395_0 FtsX-like permease family K02004 - - 2.585e-246 790.0
MMD2_k127_3167395_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 447.0
MMD2_k127_3167395_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 414.0
MMD2_k127_3167395_3 Bacterial-like globin K06886 - - 0.000000000000000000000000000000000000000000006775 166.0
MMD2_k127_3167395_4 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.0000000000000000000000000000000000000002266 151.0
MMD2_k127_3167395_5 Belongs to the alkaline phosphatase family - - - 0.0000001987 64.0
MMD2_k127_3180372_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.733e-225 715.0
MMD2_k127_3180372_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 525.0
MMD2_k127_3180372_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 525.0
MMD2_k127_3180372_3 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 302.0
MMD2_k127_3180372_4 PFAM zinc finger, DksA TraR C4-type - - - 0.000000000000000000000000000000000007821 140.0
MMD2_k127_3216876_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 503.0
MMD2_k127_3216876_1 protein conserved in bacteria K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 459.0
MMD2_k127_3216876_2 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 453.0
MMD2_k127_3216876_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 426.0
MMD2_k127_3216876_4 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 370.0
MMD2_k127_3216876_5 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 352.0
MMD2_k127_3216876_6 Binding-protein-dependent transport system inner membrane component K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 314.0
MMD2_k127_3216876_7 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 311.0
MMD2_k127_3216876_8 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000246 282.0
MMD2_k127_3216876_9 ABC transporter K01990 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009314,GO:0009628,GO:0010165,GO:0010212,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000007889 50.0
MMD2_k127_3230356_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 3.709e-304 941.0
MMD2_k127_3230356_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 9.708e-302 937.0
MMD2_k127_3230356_10 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 372.0
MMD2_k127_3230356_11 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 368.0
MMD2_k127_3230356_12 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 364.0
MMD2_k127_3230356_13 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 344.0
MMD2_k127_3230356_14 Glycosyltransferase, group 2 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 307.0
MMD2_k127_3230356_15 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008057 267.0
MMD2_k127_3230356_16 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000006147 218.0
MMD2_k127_3230356_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000002666 184.0
MMD2_k127_3230356_18 ATP synthase B/B' CF(0) K02109 - - 0.0000000000000000000000000000000000000000000000002531 180.0
MMD2_k127_3230356_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000156 150.0
MMD2_k127_3230356_2 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 6.986e-294 913.0
MMD2_k127_3230356_20 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000002538 136.0
MMD2_k127_3230356_21 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000001691 120.0
MMD2_k127_3230356_22 ATP synthase I chain K02116 - - 0.00000000000006797 76.0
MMD2_k127_3230356_23 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000006844 68.0
MMD2_k127_3230356_24 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme - - - 0.00000001568 63.0
MMD2_k127_3230356_25 PFAM glycosyl transferase family 9 K02849 - - 0.00000007497 59.0
MMD2_k127_3230356_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.838e-278 861.0
MMD2_k127_3230356_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.533e-270 836.0
MMD2_k127_3230356_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.194e-195 621.0
MMD2_k127_3230356_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 579.0
MMD2_k127_3230356_7 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 507.0
MMD2_k127_3230356_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 451.0
MMD2_k127_3230356_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 432.0
MMD2_k127_3237283_0 Heat shock 70 kDa protein K04043 - - 5.794e-295 914.0
MMD2_k127_3237283_1 AMP-binding enzyme K12508 - 6.2.1.34 1.99e-224 709.0
MMD2_k127_3237283_2 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 492.0
MMD2_k127_3237283_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000005519 237.0
MMD2_k127_3237283_4 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000003367 216.0
MMD2_k127_3237283_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000306 135.0
MMD2_k127_3240415_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1095.0
MMD2_k127_3240415_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 610.0
MMD2_k127_3240415_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 466.0
MMD2_k127_3240415_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 349.0
MMD2_k127_3240415_4 - - - - 0.000000000006533 72.0
MMD2_k127_3240415_5 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0001834 50.0
MMD2_k127_3250837_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.498e-308 949.0
MMD2_k127_3250837_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 9.147e-239 755.0
MMD2_k127_3250837_2 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 445.0
MMD2_k127_3250837_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002826 254.0
MMD2_k127_3250837_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000004609 227.0
MMD2_k127_3308696_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 558.0
MMD2_k127_3308696_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 409.0
MMD2_k127_3308696_2 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000000000003617 195.0
MMD2_k127_3308696_3 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000000006501 124.0
MMD2_k127_3308696_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000003668 112.0
MMD2_k127_3332915_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1709.0
MMD2_k127_3332915_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 5.972e-246 766.0
MMD2_k127_3332915_10 RNA-binding protein containing KH domain possibly ribosomal protein - - - 0.000000000000000000000003655 108.0
MMD2_k127_3332915_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 590.0
MMD2_k127_3332915_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 332.0
MMD2_k127_3332915_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 335.0
MMD2_k127_3332915_5 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001772 250.0
MMD2_k127_3332915_6 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000549 217.0
MMD2_k127_3332915_7 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000001049 141.0
MMD2_k127_3332915_8 - - - - 0.0000000000000000000000000000000009765 148.0
MMD2_k127_3332915_9 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000006561 111.0
MMD2_k127_3360290_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1266.0
MMD2_k127_3360290_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008854 282.0
MMD2_k127_3360290_2 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000001825 107.0
MMD2_k127_3360290_3 Transcriptional regulatory protein, C terminal - - - 0.00000000000005977 74.0
MMD2_k127_336622_0 elongation factor G K02355 - - 4.37e-283 893.0
MMD2_k127_336622_1 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 304.0
MMD2_k127_336622_10 - - - - 0.0000000000000000000000000000000000003232 145.0
MMD2_k127_336622_11 Macrocin-O-methyltransferase (TylF) - - - 0.000000000000000000000000000000002212 138.0
MMD2_k127_336622_13 Protein of unknown function (DUF2721) - - - 0.00000000000000000000000007187 112.0
MMD2_k127_336622_2 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008679 267.0
MMD2_k127_336622_3 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003236 256.0
MMD2_k127_336622_4 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007719 251.0
MMD2_k127_336622_5 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000000000000113 224.0
MMD2_k127_336622_6 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000004024 244.0
MMD2_k127_336622_7 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000000001003 194.0
MMD2_k127_336622_8 SnoaL-like domain - - - 0.000000000000000000000000000000000000000000001149 167.0
MMD2_k127_336622_9 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000000000000000000000008747 166.0
MMD2_k127_3414229_0 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 3.606e-213 670.0
MMD2_k127_3414229_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 629.0
MMD2_k127_3414229_10 - K11477 - - 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
MMD2_k127_3414229_11 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406,K03776,K05874 - - 0.00000000000000000000000000000000000000000000000000006479 199.0
MMD2_k127_3414229_12 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000002796 183.0
MMD2_k127_3414229_13 - - - - 0.000000000000000000000001441 118.0
MMD2_k127_3414229_14 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 - 6.3.4.15 0.0001589 49.0
MMD2_k127_3414229_2 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 542.0
MMD2_k127_3414229_3 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 529.0
MMD2_k127_3414229_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 497.0
MMD2_k127_3414229_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 394.0
MMD2_k127_3414229_6 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 334.0
MMD2_k127_3414229_7 Protein of unknown function (DUF2167) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 292.0
MMD2_k127_3414229_8 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000713 263.0
MMD2_k127_3414229_9 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000004993 259.0
MMD2_k127_3447089_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 5.303e-200 630.0
MMD2_k127_3447089_1 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 404.0
MMD2_k127_3447089_2 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 307.0
MMD2_k127_3461342_0 Hydrolase CocE NonD family K06978 - - 8.845e-299 942.0
MMD2_k127_3461342_1 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 594.0
MMD2_k127_3461342_10 Twin-arginine translocation pathway signal protein - - - 0.00000000000000000001524 99.0
MMD2_k127_3461342_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 473.0
MMD2_k127_3461342_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 357.0
MMD2_k127_3461342_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 327.0
MMD2_k127_3461342_5 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 301.0
MMD2_k127_3461342_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 284.0
MMD2_k127_3461342_7 Diguanylate cyclase K21023 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000001354 250.0
MMD2_k127_3461342_8 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000003292 188.0
MMD2_k127_3461342_9 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000000000002161 173.0
MMD2_k127_3540608_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 509.0
MMD2_k127_3540608_1 13-prostaglandin reductase activity K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 395.0
MMD2_k127_3540608_2 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 351.0
MMD2_k127_3540608_3 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 327.0
MMD2_k127_3540608_4 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008271 311.0
MMD2_k127_3540608_5 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 307.0
MMD2_k127_3540608_6 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003073 251.0
MMD2_k127_3540608_7 methyltransferase activity K21310 - 2.1.1.334 0.00000000000000000000000000000000000000000000000000000007966 199.0
MMD2_k127_3567572_0 Diguanylate cyclase - - - 5.285e-261 836.0
MMD2_k127_3567572_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 3.875e-250 781.0
MMD2_k127_3567572_10 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000007119 253.0
MMD2_k127_3567572_11 Methyltransferase domain - - - 0.000000000000000000000000000000000004674 144.0
MMD2_k127_3567572_12 Pfam:DUF59 - - - 0.00000000000000000000000001921 120.0
MMD2_k127_3567572_13 Alpha/beta hydrolase family - - - 0.00000000000000000000003743 115.0
MMD2_k127_3567572_14 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000001324 111.0
MMD2_k127_3567572_2 glycolate oxidase subunit GlcD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 537.0
MMD2_k127_3567572_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 464.0
MMD2_k127_3567572_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004959 362.0
MMD2_k127_3567572_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 326.0
MMD2_k127_3567572_6 aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 333.0
MMD2_k127_3567572_7 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004734 282.0
MMD2_k127_3567572_8 Glutathione S-Transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000002374 267.0
MMD2_k127_3567572_9 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006788 273.0
MMD2_k127_3569974_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 8.966e-293 923.0
MMD2_k127_3569974_1 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 467.0
MMD2_k127_3569974_2 LysE type translocator - - - 0.000000000000000000000000000000000003564 160.0
MMD2_k127_3569974_3 Protein conserved in bacteria - - - 0.00000000000000000000000000000000001124 158.0
MMD2_k127_3572313_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 2.903e-275 863.0
MMD2_k127_3572313_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 484.0
MMD2_k127_3572313_10 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000004938 132.0
MMD2_k127_3572313_11 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000000000000000005975 122.0
MMD2_k127_3572313_12 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000000000003452 126.0
MMD2_k127_3572313_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003653 452.0
MMD2_k127_3572313_3 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 390.0
MMD2_k127_3572313_4 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 398.0
MMD2_k127_3572313_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 364.0
MMD2_k127_3572313_6 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 348.0
MMD2_k127_3572313_7 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000105 253.0
MMD2_k127_3572313_8 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000394 232.0
MMD2_k127_3572313_9 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000009118 228.0
MMD2_k127_3577473_0 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 471.0
MMD2_k127_3577473_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 394.0
MMD2_k127_3577473_2 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000009118 156.0
MMD2_k127_3577473_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000004296 147.0
MMD2_k127_3577473_4 protein conserved in bacteria - - - 0.000000000002665 68.0
MMD2_k127_359793_0 ABC transporter K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 303.0
MMD2_k127_359793_1 COG0451 Nucleoside-diphosphate-sugar epimerases K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001805 284.0
MMD2_k127_359793_2 PFAM ABC-2 type transporter K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009602 274.0
MMD2_k127_359793_3 Glycosyl transferase, family 2 K12997 - - 0.0000000000000000000000000000000000000000000000000000000000000000004401 240.0
MMD2_k127_359793_4 Methyltransferase domain - - - 0.00000000000598 76.0
MMD2_k127_359793_5 TIGRFAM lipopolysaccharide heptosyltransferase I K02841 - - 0.00004604 56.0
MMD2_k127_3600531_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 5.437e-210 674.0
MMD2_k127_3600531_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 546.0
MMD2_k127_3600531_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 387.0
MMD2_k127_3600531_3 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 328.0
MMD2_k127_3600531_4 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000002023 239.0
MMD2_k127_3600531_5 gag-polyprotein putative aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000007413 185.0
MMD2_k127_3602348_0 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 479.0
MMD2_k127_3602348_1 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 469.0
MMD2_k127_3602348_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 458.0
MMD2_k127_3602348_3 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 337.0
MMD2_k127_3602348_4 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 352.0
MMD2_k127_3602348_5 receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 316.0
MMD2_k127_3602348_6 Periplasmic binding protein K02016,K06858 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 311.0
MMD2_k127_3602348_7 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000009749 224.0
MMD2_k127_3602348_8 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000001154 207.0
MMD2_k127_3602348_9 Chemotaxis signal transduction protein K03408 - - 0.000000000118 62.0
MMD2_k127_3677539_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 4.053e-317 978.0
MMD2_k127_3677539_1 PFAM acyl-CoA dehydrogenase domain protein K00252 - 1.3.8.6 5.244e-233 725.0
MMD2_k127_3677539_2 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 608.0
MMD2_k127_3677539_3 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 632.0
MMD2_k127_3677539_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007335 561.0
MMD2_k127_3677539_5 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 414.0
MMD2_k127_3677539_6 Protein of unknown function (DUF3187) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006851 271.0
MMD2_k127_3677539_7 Universal stress protein family - - - 0.000000000000000000000000000000000000000004216 159.0
MMD2_k127_3677539_8 Uncharacterized ACR, COG1678 - - - 0.000000000000000000000002961 110.0
MMD2_k127_3677539_9 Uncharacterized ACR, COG1678 - - - 0.0000000000000002296 90.0
MMD2_k127_3718186_0 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 346.0
MMD2_k127_3718186_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007227 286.0
MMD2_k127_3718186_2 fumarylacetoacetate (FAA) hydrolase K16165 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0008948,GO:0016787,GO:0016822,GO:0016823,GO:0016829,GO:0016830,GO:0016831,GO:0018773,GO:0031974,GO:0031981,GO:0034545,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0070013 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000001185 271.0
MMD2_k127_3718186_3 TIGRFAM maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000008366 266.0
MMD2_k127_3718186_4 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001289 263.0
MMD2_k127_3718186_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000001232 117.0
MMD2_k127_3791150_0 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 1.949e-229 721.0
MMD2_k127_3791150_1 ROK family K00847 - 2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 431.0
MMD2_k127_3791150_2 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000792 246.0
MMD2_k127_3791150_3 Prokaryotic cytochrome b561 K12262 - - 0.0000000000000000000000000000000002383 138.0
MMD2_k127_3821069_0 TIGRFAM exopolysaccharide transport protein family K16554 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 589.0
MMD2_k127_3821069_1 Putative beta-barrel porin 2 K20920 - - 0.000000000000000000000000000000000000000000000000000000000000002586 231.0
MMD2_k127_3821069_2 COG1596 Periplasmic protein involved in polysaccharide export K20988 - - 0.0000000000000000000000000000000000000000000000001009 196.0
MMD2_k127_3821069_3 capsular polysaccharide biosynthesis protein K01104 - 3.1.3.48 0.0000000000000000001074 91.0
MMD2_k127_382850_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.0 1144.0
MMD2_k127_382850_1 GMP synthase C terminal domain K01951 - 6.3.5.2 2.23e-278 866.0
MMD2_k127_382850_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.29e-241 753.0
MMD2_k127_382850_3 Aminomethyltransferase folate-binding domain K15066 - 2.1.1.341 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 533.0
MMD2_k127_382850_4 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 351.0
MMD2_k127_382850_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000178 223.0
MMD2_k127_382850_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000006207 136.0
MMD2_k127_382850_7 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000001143 105.0
MMD2_k127_382850_8 Domain of unknown function (DUF4118) - - - 0.0000000000002384 78.0
MMD2_k127_3835546_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 2.607e-288 903.0
MMD2_k127_3835546_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 518.0
MMD2_k127_3835546_2 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004361 467.0
MMD2_k127_3835546_3 Transcriptional regulator crp fnr family K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001253 260.0
MMD2_k127_3835546_4 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000001253 222.0
MMD2_k127_3873456_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1393.0
MMD2_k127_3873456_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 1.237e-294 920.0
MMD2_k127_3873456_10 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008719 265.0
MMD2_k127_3873456_11 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000000000009574 202.0
MMD2_k127_3873456_12 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000004637 207.0
MMD2_k127_3873456_13 Protein of unknown function (DUF1643) - - - 0.0000000000000000000000000000000000000000000000000004358 188.0
MMD2_k127_3873456_14 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000000000000001279 192.0
MMD2_k127_3873456_15 Thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000001264 161.0
MMD2_k127_3873456_16 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000001112 122.0
MMD2_k127_3873456_17 mutations in this gene affect RecA-independent excision of transposons and affects Mu bacteriophage growth K15738 - - 0.0000000000000000000000004049 106.0
MMD2_k127_3873456_18 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.0000000000000000000002772 113.0
MMD2_k127_3873456_19 PFAM Fibronectin type III domain - - - 0.0000000000000000227 96.0
MMD2_k127_3873456_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 2.648e-223 705.0
MMD2_k127_3873456_20 ABC transporter K15738 - - 0.0008326 44.0
MMD2_k127_3873456_3 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 390.0
MMD2_k127_3873456_4 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 395.0
MMD2_k127_3873456_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 377.0
MMD2_k127_3873456_6 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 382.0
MMD2_k127_3873456_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 364.0
MMD2_k127_3873456_8 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 295.0
MMD2_k127_3873456_9 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 292.0
MMD2_k127_3911746_0 III protein, CoA-transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 505.0
MMD2_k127_3911746_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 359.0
MMD2_k127_3911746_2 Cytochrome c-type biogenesis protein K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004036 263.0
MMD2_k127_3911746_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000001889 252.0
MMD2_k127_3911746_4 Gkycosyl transferase family 4 group - - - 0.000001606 50.0
MMD2_k127_3956565_0 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 543.0
MMD2_k127_3956565_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 453.0
MMD2_k127_3956565_10 Protein of unknown function (DUF3108) - - - 0.000000000000000000000001287 117.0
MMD2_k127_3956565_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000001288 94.0
MMD2_k127_3956565_2 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 364.0
MMD2_k127_3956565_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 354.0
MMD2_k127_3956565_4 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 293.0
MMD2_k127_3956565_5 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002026 266.0
MMD2_k127_3956565_6 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000001754 264.0
MMD2_k127_3956565_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000005179 205.0
MMD2_k127_3956565_8 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000000000000006286 181.0
MMD2_k127_3956565_9 Ribosomal L28 family K02902 - - 0.000000000000000000000000000003713 122.0
MMD2_k127_3957203_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 506.0
MMD2_k127_3957203_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009811 280.0
MMD2_k127_3957203_2 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000001681 205.0
MMD2_k127_3957203_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000005057 157.0
MMD2_k127_3957203_4 PAS domain - - - 0.00001244 58.0
MMD2_k127_3993775_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 7.97e-230 726.0
MMD2_k127_3993775_1 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 7.398e-210 673.0
MMD2_k127_3993775_10 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008766,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0047480,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 6.3.2.10 0.00000000000007929 75.0
MMD2_k127_3993775_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 597.0
MMD2_k127_3993775_3 AMP-binding enzyme C-terminal domain K02182 - 6.2.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 552.0
MMD2_k127_3993775_4 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 529.0
MMD2_k127_3993775_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002729 499.0
MMD2_k127_3993775_6 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008143 373.0
MMD2_k127_3993775_7 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000001843 161.0
MMD2_k127_3993775_8 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.00000000000000000000000000000000000000001778 154.0
MMD2_k127_3993775_9 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.0000000000000000008879 93.0
MMD2_k127_3999462_0 DNA polymerase X family K02347 - - 5.161e-245 769.0
MMD2_k127_3999462_1 tRNA synthetases class I (E and Q), catalytic domain K01885 - 6.1.1.17 5.504e-199 629.0
MMD2_k127_3999462_10 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000135 215.0
MMD2_k127_3999462_11 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000005602 203.0
MMD2_k127_3999462_12 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000001414 113.0
MMD2_k127_3999462_13 Carboxymuconolactone decarboxylase family - - - 0.000000000000000002392 84.0
MMD2_k127_3999462_15 Saccharomyces cerevisiae YCR051W K06867 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0032991,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464 - 0.00000003408 57.0
MMD2_k127_3999462_16 - - - - 0.0000004489 52.0
MMD2_k127_3999462_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 575.0
MMD2_k127_3999462_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 387.0
MMD2_k127_3999462_4 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001868 276.0
MMD2_k127_3999462_5 Transport and Golgi organisation 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
MMD2_k127_3999462_6 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002881 245.0
MMD2_k127_3999462_7 Belongs to the GcvT family K06980 - - 0.0000000000000000000000000000000000000000000000000000000000000000006674 243.0
MMD2_k127_3999462_8 DNA polymerase III, delta' K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000004455 243.0
MMD2_k127_3999462_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000003805 226.0
MMD2_k127_4008080_0 UPF0313 protein - - - 0.0 1084.0
MMD2_k127_4008080_1 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 337.0
MMD2_k127_4008080_2 cyclic nucleotide binding K01420 - - 0.000000000000000000000000000000000000000000000000000000000000008737 226.0
MMD2_k127_4008080_3 - - - - 0.000000000000002834 87.0
MMD2_k127_4008080_4 - - - - 0.000000000000009142 80.0
MMD2_k127_4019481_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 1.465e-274 867.0
MMD2_k127_4019481_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 517.0
MMD2_k127_4019481_2 Trypsin-like peptidase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 364.0
MMD2_k127_4019481_3 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 349.0
MMD2_k127_4019481_4 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000001334 211.0
MMD2_k127_4032175_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 568.0
MMD2_k127_4032175_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 546.0
MMD2_k127_4032175_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 469.0
MMD2_k127_4032175_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 309.0
MMD2_k127_4032175_4 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 286.0
MMD2_k127_4032175_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000008174 227.0
MMD2_k127_4032175_6 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000585 72.0
MMD2_k127_4058273_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.32e-265 846.0
MMD2_k127_4058273_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 612.0
MMD2_k127_4058273_10 Diguanylate cyclase K13069,K21021 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005522 278.0
MMD2_k127_4058273_11 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006878 259.0
MMD2_k127_4058273_12 NnrS protein - - - 0.000000000000000000000000000000000000000000000000000000000000000678 235.0
MMD2_k127_4058273_13 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000002464 193.0
MMD2_k127_4058273_14 - - - - 0.00000000000000000000000000000000000000000000000002275 199.0
MMD2_k127_4058273_15 - - - - 0.00000000006796 73.0
MMD2_k127_4058273_16 Adenylate and Guanylate cyclase catalytic domain - - - 0.00000008551 66.0
MMD2_k127_4058273_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006016 573.0
MMD2_k127_4058273_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 571.0
MMD2_k127_4058273_4 SMP-30/Gluconolaconase/LRE-like region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 541.0
MMD2_k127_4058273_5 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 526.0
MMD2_k127_4058273_6 Transcriptional regulator, LysR family K13794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 509.0
MMD2_k127_4058273_7 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003316 482.0
MMD2_k127_4058273_8 PFAM Prokaryotic protein of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 436.0
MMD2_k127_4058273_9 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002843 282.0
MMD2_k127_4065641_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 4.394e-252 782.0
MMD2_k127_4065641_1 Mur ligase family, catalytic domain K02558 - 6.3.2.45 3.375e-204 645.0
MMD2_k127_4065641_10 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000000000000000000000073 193.0
MMD2_k127_4065641_11 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000000006431 193.0
MMD2_k127_4065641_12 - - - - 0.0000000000000000000000000000000000000000000000018 183.0
MMD2_k127_4065641_13 Histidine triad (Hit) protein K02503 - - 0.0000000000000000000000000000000000000000001933 171.0
MMD2_k127_4065641_14 Protein of unknown function (DUF3426) - - - 0.000000000000000000000000000000000000002153 164.0
MMD2_k127_4065641_15 Redoxin domain protein - - - 0.000000000000000000000000000000000001369 144.0
MMD2_k127_4065641_16 RNB K01147 - 3.1.13.1 0.0000000000000000000000000000007146 127.0
MMD2_k127_4065641_17 Membrane fusogenic activity K09806 - - 0.0000000000000007036 79.0
MMD2_k127_4065641_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.18e-196 625.0
MMD2_k127_4065641_3 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 556.0
MMD2_k127_4065641_4 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 436.0
MMD2_k127_4065641_5 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 359.0
MMD2_k127_4065641_6 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009347 286.0
MMD2_k127_4065641_7 Dehydroquinase class II K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000006986 203.0
MMD2_k127_4065641_8 Putative beta-barrel porin-2, OmpL-like. bbp2 - - - 0.000000000000000000000000000000000000000000000000000000008337 213.0
MMD2_k127_4065641_9 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000105 199.0
MMD2_k127_4072726_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 1.131e-278 889.0
MMD2_k127_4072726_1 Methionine synthase K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 549.0
MMD2_k127_4072726_2 3'(2'),5'-bisphosphate nucleotidase K01082 - 3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 309.0
MMD2_k127_4072726_3 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000001249 197.0
MMD2_k127_4072726_4 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000001931 191.0
MMD2_k127_4072726_5 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000002318 181.0
MMD2_k127_4072726_6 - - - - 0.000000000000000000000000000000000000011 168.0
MMD2_k127_4072726_7 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000006447 145.0
MMD2_k127_4072726_8 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.00000000000000000000000000001654 119.0
MMD2_k127_4072726_9 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0004016 49.0
MMD2_k127_4079385_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 7.437e-206 651.0
MMD2_k127_4079385_1 VanZ like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004629 279.0
MMD2_k127_4079385_2 ferredoxin - - - 0.0000000000000000000000000000000000000000000001905 171.0
MMD2_k127_4079385_3 Alpha beta K07018 - - 0.000000000000000000000000000184 116.0
MMD2_k127_4097416_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.139e-237 736.0
MMD2_k127_4097416_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 455.0
MMD2_k127_4097416_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000008277 220.0
MMD2_k127_4097416_11 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000115 211.0
MMD2_k127_4097416_12 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000005321 190.0
MMD2_k127_4097416_13 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000005895 195.0
MMD2_k127_4097416_14 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000000008908 178.0
MMD2_k127_4097416_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000000000008286 176.0
MMD2_k127_4097416_16 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000001514 163.0
MMD2_k127_4097416_17 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000004877 160.0
MMD2_k127_4097416_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000001348 137.0
MMD2_k127_4097416_19 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000002672 146.0
MMD2_k127_4097416_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 341.0
MMD2_k127_4097416_20 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000003027 124.0
MMD2_k127_4097416_21 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000002993 91.0
MMD2_k127_4097416_22 Ribosomal protein L30 K02907 - - 0.000000000000000000108 91.0
MMD2_k127_4097416_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 327.0
MMD2_k127_4097416_4 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 307.0
MMD2_k127_4097416_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007052 301.0
MMD2_k127_4097416_6 50S ribosomal protein L4 K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 293.0
MMD2_k127_4097416_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001053 283.0
MMD2_k127_4097416_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001214 258.0
MMD2_k127_4097416_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001128 252.0
MMD2_k127_413343_0 Class II Aldolase and Adducin N-terminal domain - - - 1.108e-275 861.0
MMD2_k127_413343_1 BT1 family - - - 5.047e-229 737.0
MMD2_k127_413343_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 437.0
MMD2_k127_413343_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 319.0
MMD2_k127_413343_4 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001998 259.0
MMD2_k127_413343_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000001666 206.0
MMD2_k127_413343_6 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000004123 200.0
MMD2_k127_413343_7 - - - - 0.00000000000000000000000000000000000000000000000002533 186.0
MMD2_k127_413343_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000001964 163.0
MMD2_k127_4148137_0 Rieske [2Fe-2S] domain - - - 7.775e-199 627.0
MMD2_k127_4148137_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 435.0
MMD2_k127_4148137_10 - - - - 0.000000000000000000009116 96.0
MMD2_k127_4148137_11 Protein of unknown function (DUF3617) - - - 0.000000000001741 82.0
MMD2_k127_4148137_2 Pyridoxal phosphate biosynthetic protein PdxA K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 415.0
MMD2_k127_4148137_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 406.0
MMD2_k127_4148137_4 Sir2 family K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 312.0
MMD2_k127_4148137_5 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 329.0
MMD2_k127_4148137_6 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001094 286.0
MMD2_k127_4148137_7 Belongs to the peptidase S11 family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000005692 252.0
MMD2_k127_4148137_8 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000008512 251.0
MMD2_k127_4148137_9 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000002399 178.0
MMD2_k127_4177721_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1439.0
MMD2_k127_4177721_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.254e-278 878.0
MMD2_k127_4177721_10 dioxygenase of extradiol dioxygenase family K06991 - - 0.000000000000000000000000000000000000000000000000000000000000000002442 228.0
MMD2_k127_4177721_11 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000003612 208.0
MMD2_k127_4177721_12 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000002647 183.0
MMD2_k127_4177721_13 Putative regulatory protein - - - 0.000000000000000000000000000000000005733 138.0
MMD2_k127_4177721_14 Domain of Unknown Function (DUF349) - - - 0.000000000000000000000000000000002072 149.0
MMD2_k127_4177721_2 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 429.0
MMD2_k127_4177721_3 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 409.0
MMD2_k127_4177721_4 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 395.0
MMD2_k127_4177721_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 381.0
MMD2_k127_4177721_6 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 342.0
MMD2_k127_4177721_7 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 324.0
MMD2_k127_4177721_8 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 289.0
MMD2_k127_4177721_9 of poly-gamma-glutamate biosynthesis (Capsule K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003703 274.0
MMD2_k127_4280600_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1651.0
MMD2_k127_4280600_1 ABC transporter K06020 - 3.6.3.25 1.348e-283 879.0
MMD2_k127_4280600_2 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 472.0
MMD2_k127_4280600_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 368.0
MMD2_k127_4280600_4 response regulator K02483,K07661,K18073 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 329.0
MMD2_k127_4280600_5 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000000000000000000009755 235.0
MMD2_k127_4280600_6 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000007271 156.0
MMD2_k127_4280600_7 ABC transporter K06020 - 3.6.3.25 0.000000000000000000000001453 106.0
MMD2_k127_4280600_8 Heavy-metal resistance - - - 0.000000000000000000000006653 108.0
MMD2_k127_432113_0 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 386.0
MMD2_k127_432113_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 385.0
MMD2_k127_432113_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 369.0
MMD2_k127_432113_3 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000002811 229.0
MMD2_k127_432113_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000001744 175.0
MMD2_k127_43569_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 504.0
MMD2_k127_43569_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 413.0
MMD2_k127_43569_2 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 321.0
MMD2_k127_43569_3 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 302.0
MMD2_k127_43569_4 Histidine kinase K02484 - 2.7.13.3 0.000000000000000000002944 94.0
MMD2_k127_438390_0 Belongs to the peptidase M16 family K07263 - - 1.451e-222 712.0
MMD2_k127_438390_1 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002961 278.0
MMD2_k127_438390_2 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000005054 252.0
MMD2_k127_438390_3 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000006919 241.0
MMD2_k127_4392237_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 5.298e-221 712.0
MMD2_k127_4392237_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 462.0
MMD2_k127_4392237_10 THUMP - - - 0.00000000000000000000000000000005746 132.0
MMD2_k127_4392237_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 326.0
MMD2_k127_4392237_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008375 299.0
MMD2_k127_4392237_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000007706 275.0
MMD2_k127_4392237_5 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009449 269.0
MMD2_k127_4392237_6 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000003134 227.0
MMD2_k127_4392237_7 [2Fe-2S] binding domain K07302,K18029 - 1.17.2.1,1.3.99.16 0.000000000000000000000000000000000000000000000000000000005045 215.0
MMD2_k127_4392237_8 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000000000000000000000004201 202.0
MMD2_k127_4392237_9 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000002554 178.0
MMD2_k127_4401574_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.727e-226 720.0
MMD2_k127_4401574_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 507.0
MMD2_k127_4401574_2 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004196 323.0
MMD2_k127_4401574_3 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000009408 263.0
MMD2_k127_4401574_4 Polynucleotide kinase 3 phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000000000000801 232.0
MMD2_k127_4401574_5 Protein of unknown function DUF45 K07043 - - 0.000001354 59.0
MMD2_k127_4412618_0 Protein of unknown function - - - 2.093e-241 786.0
MMD2_k127_4412618_1 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003494 413.0
MMD2_k127_4428870_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 2.821e-214 671.0
MMD2_k127_4428870_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 562.0
MMD2_k127_4428870_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 314.0
MMD2_k127_4428870_3 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001053 268.0
MMD2_k127_4428870_4 - - - - 0.0000000000000000000000000000000000000000004765 164.0
MMD2_k127_4428870_5 - - - - 0.00000000000000000000000000000000000004932 150.0
MMD2_k127_4428870_6 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000001446 140.0
MMD2_k127_4428870_7 VanZ like family - - - 0.000000000000000000000000000006624 122.0
MMD2_k127_4428870_8 sulfur carrier activity K04085 - - 0.00000000000000000000000001583 111.0
MMD2_k127_4453711_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 9.769e-314 972.0
MMD2_k127_4453711_1 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 587.0
MMD2_k127_4453711_2 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 578.0
MMD2_k127_4453711_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 551.0
MMD2_k127_4453711_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 430.0
MMD2_k127_4453711_5 Modulates RecA activity K03565 - - 0.00000000000000000000000001089 115.0
MMD2_k127_4469926_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 6.997e-259 811.0
MMD2_k127_4469926_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008039 546.0
MMD2_k127_4469926_10 Protein conserved in bacteria K09922 - - 0.0000000000000000000000000000000000000000000001051 177.0
MMD2_k127_4469926_11 Preprotein translocase, YajC subunit K03210 - - 0.0000000000000000000000000000000008356 133.0
MMD2_k127_4469926_12 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000001673 129.0
MMD2_k127_4469926_13 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000001148 121.0
MMD2_k127_4469926_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 552.0
MMD2_k127_4469926_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009399 417.0
MMD2_k127_4469926_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 405.0
MMD2_k127_4469926_5 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 338.0
MMD2_k127_4469926_6 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 308.0
MMD2_k127_4469926_7 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 290.0
MMD2_k127_4469926_8 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) - - - 0.00000000000000000000000000000000000000000000000000000000006209 208.0
MMD2_k127_4469926_9 Putative zinc-finger - - - 0.000000000000000000000000000000000000000000000000109 184.0
MMD2_k127_4605268_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1097.0
MMD2_k127_4605268_1 Ferrous iron transport protein B K04759 - - 7.906e-239 752.0
MMD2_k127_4605268_10 - - - - 0.000000000000005204 89.0
MMD2_k127_4605268_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 389.0
MMD2_k127_4605268_3 Four helix bundle sensory module for signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 353.0
MMD2_k127_4605268_4 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 288.0
MMD2_k127_4605268_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 292.0
MMD2_k127_4605268_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003808 283.0
MMD2_k127_4605268_7 membrane K15977 - - 0.000000000000000000000000000000000000037 147.0
MMD2_k127_4605268_8 - - - - 0.00000000000000000006258 92.0
MMD2_k127_4605268_9 PFAM FeoA family protein K04758 - - 0.0000000000000002009 84.0
MMD2_k127_4635052_0 Xanthine dehydrogenase K03520 - 1.2.5.3 1.826e-273 863.0
MMD2_k127_4635052_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 3.677e-260 812.0
MMD2_k127_4635052_2 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.521e-244 761.0
MMD2_k127_4635052_3 Transporter - - - 6.166e-208 668.0
MMD2_k127_4635052_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 372.0
MMD2_k127_4635052_5 Tar ligand binding domain homologue - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 363.0
MMD2_k127_4635052_6 TRAP transporter solute receptor TAXI family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002532 298.0
MMD2_k127_4635052_7 Archease protein family (MTH1598/TM1083) - - - 0.0000000000000000000000000000000000000000000000000000005008 198.0
MMD2_k127_4639827_0 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 541.0
MMD2_k127_4639827_1 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 302.0
MMD2_k127_4639827_2 Belongs to the MenA family. Type 1 subfamily K02548 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006775,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009233,GO:0009234,GO:0009987,GO:0016020,GO:0016740,GO:0016765,GO:0032194,GO:0042180,GO:0042181,GO:0042362,GO:0042371,GO:0042373,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046428,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901576,GO:1901661,GO:1901663 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000005318 261.0
MMD2_k127_4639827_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000002574 58.0
MMD2_k127_467077_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1274.0
MMD2_k127_467077_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 4.013e-298 920.0
MMD2_k127_467077_2 type I secretion outer membrane protein, TolC K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 435.0
MMD2_k127_467077_3 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 420.0
MMD2_k127_467077_4 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 296.0
MMD2_k127_467077_5 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 290.0
MMD2_k127_467077_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004797 282.0
MMD2_k127_467077_7 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000003745 259.0
MMD2_k127_467077_8 Bacterial transcriptional repressor C-terminal K09017 - - 0.000000000000000000000000000000000000000000000000000000000000000002538 233.0
MMD2_k127_4742370_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 576.0
MMD2_k127_4742370_1 FAD dependent oxidoreductase K00285 - 1.4.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 460.0
MMD2_k127_4742370_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 409.0
MMD2_k127_4742370_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 367.0
MMD2_k127_4742370_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 351.0
MMD2_k127_4742370_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 301.0
MMD2_k127_4742370_6 isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000000000000004394 206.0
MMD2_k127_4742370_7 PFAM PHP C-terminal K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.00000000000000000000000000000001668 135.0
MMD2_k127_4749331_0 E1 component K00164 - 1.2.4.2 0.0 1380.0
MMD2_k127_4749331_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1034.0
MMD2_k127_4749331_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003952 306.0
MMD2_k127_4749331_11 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000005947 237.0
MMD2_k127_4749331_12 nucleic acid-binding protein, contains PIN domain - - - 0.0000000000000000000001489 108.0
MMD2_k127_4749331_14 Haem-degrading - - - 0.000000000000000000009335 94.0
MMD2_k127_4749331_15 Rubredoxin - - - 0.000000000001679 67.0
MMD2_k127_4749331_16 Haem-degrading K11477 - - 0.00000000001861 68.0
MMD2_k127_4749331_17 Protein of unknown function (DUF2914) - - - 0.00000003259 66.0
MMD2_k127_4749331_2 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 1.869e-297 923.0
MMD2_k127_4749331_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.973e-261 816.0
MMD2_k127_4749331_4 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 1.368e-207 654.0
MMD2_k127_4749331_5 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 557.0
MMD2_k127_4749331_6 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 462.0
MMD2_k127_4749331_7 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 432.0
MMD2_k127_4749331_8 Bacterial regulatory helix-turn-helix protein, lysR family K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 375.0
MMD2_k127_4749331_9 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007172 366.0
MMD2_k127_4750307_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 443.0
MMD2_k127_4750307_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 357.0
MMD2_k127_4750307_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001569 282.0
MMD2_k127_4750307_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000005377 231.0
MMD2_k127_4750307_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
MMD2_k127_4750307_5 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000002463 209.0
MMD2_k127_4750307_6 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000006125 216.0
MMD2_k127_4758068_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.278e-305 951.0
MMD2_k127_4758068_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.06e-296 923.0
MMD2_k127_4758068_10 PFAM AAA ATPase central domain protein K06413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 432.0
MMD2_k127_4758068_11 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 425.0
MMD2_k127_4758068_12 Glutathionylspermidine synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004476 428.0
MMD2_k127_4758068_13 Fructose-1-6-bisphosphatase, N-terminal domain K01086 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 416.0
MMD2_k127_4758068_14 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 406.0
MMD2_k127_4758068_15 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 359.0
MMD2_k127_4758068_16 ABC-type uncharacterized transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007097 357.0
MMD2_k127_4758068_17 Transcriptional regulator K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 324.0
MMD2_k127_4758068_18 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001026 284.0
MMD2_k127_4758068_19 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006964 287.0
MMD2_k127_4758068_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 9.173e-272 843.0
MMD2_k127_4758068_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000206 269.0
MMD2_k127_4758068_21 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000008965 270.0
MMD2_k127_4758068_22 Stress-induced protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002756 290.0
MMD2_k127_4758068_23 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008513 261.0
MMD2_k127_4758068_24 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000002068 235.0
MMD2_k127_4758068_25 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000001602 245.0
MMD2_k127_4758068_26 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.00000000000000000000000000000000000000000000000000000001511 218.0
MMD2_k127_4758068_27 Domain of Unknown Function (DUF350) K08989 - - 0.0000000000000000000000000000866 121.0
MMD2_k127_4758068_28 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000005364 104.0
MMD2_k127_4758068_29 - - - - 0.000000000001045 72.0
MMD2_k127_4758068_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 2.218e-222 695.0
MMD2_k127_4758068_30 Domain of unknown function (DUF4340) - - - 0.000000001819 70.0
MMD2_k127_4758068_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 3.431e-203 640.0
MMD2_k127_4758068_5 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 569.0
MMD2_k127_4758068_6 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 569.0
MMD2_k127_4758068_7 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 553.0
MMD2_k127_4758068_8 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 535.0
MMD2_k127_4758068_9 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 488.0
MMD2_k127_478994_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 547.0
MMD2_k127_478994_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 404.0
MMD2_k127_478994_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 377.0
MMD2_k127_478994_3 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 286.0
MMD2_k127_478994_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000001939 119.0
MMD2_k127_4827751_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 6.264e-270 838.0
MMD2_k127_4827751_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 591.0
MMD2_k127_4827751_2 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 403.0
MMD2_k127_4827751_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000005053 173.0
MMD2_k127_4870289_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 3.389e-261 815.0
MMD2_k127_4870289_1 Cytochrome b(N-terminal)/b6/petB - - - 2.307e-244 771.0
MMD2_k127_4870289_10 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000006919 241.0
MMD2_k127_4870289_11 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000104 221.0
MMD2_k127_4870289_12 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000597 118.0
MMD2_k127_4870289_13 - - - - 0.000000000002051 69.0
MMD2_k127_4870289_14 Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000006998 61.0
MMD2_k127_4870289_15 Cytochrome oxidase assembly protein K02259 - - 0.0005626 51.0
MMD2_k127_4870289_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 602.0
MMD2_k127_4870289_3 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 545.0
MMD2_k127_4870289_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 530.0
MMD2_k127_4870289_5 Cytochrome C and Quinol oxidase polypeptide I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 494.0
MMD2_k127_4870289_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 496.0
MMD2_k127_4870289_7 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 426.0
MMD2_k127_4870289_8 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 315.0
MMD2_k127_4870289_9 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005162 259.0
MMD2_k127_4874034_0 B12 binding domain K00548 - 2.1.1.13 0.0 1709.0
MMD2_k127_4874034_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 2.667e-197 625.0
MMD2_k127_4874034_2 PFAM TrkA-N domain protein K03499 - - 4.576e-197 623.0
MMD2_k127_4874034_3 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 438.0
MMD2_k127_4874034_4 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000001455 207.0
MMD2_k127_4874034_5 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000001246 133.0
MMD2_k127_4930862_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 2.268e-264 823.0
MMD2_k127_4930862_1 PFAM Glycoside hydrolase 15-related - - - 3.996e-256 805.0
MMD2_k127_4930862_10 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.00000000000000000000000000000000001194 139.0
MMD2_k127_4930862_11 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000006239 71.0
MMD2_k127_4930862_2 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 2.806e-252 783.0
MMD2_k127_4930862_3 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 5.307e-230 722.0
MMD2_k127_4930862_4 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 3.966e-201 644.0
MMD2_k127_4930862_5 glycolate oxidase iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 559.0
MMD2_k127_4930862_6 FAD binding domain K11472 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 445.0
MMD2_k127_4930862_7 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 460.0
MMD2_k127_4930862_8 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 359.0
MMD2_k127_4930862_9 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000001799 250.0
MMD2_k127_493680_0 Transketolase, pyrimidine binding domain - - - 1.893e-265 827.0
MMD2_k127_493680_1 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 292.0
MMD2_k127_493680_2 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001183 274.0
MMD2_k127_493680_3 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008656 270.0
MMD2_k127_493680_4 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000002515 181.0
MMD2_k127_4943826_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 427.0
MMD2_k127_4943826_1 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 374.0
MMD2_k127_4943826_2 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 334.0
MMD2_k127_4943826_3 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 340.0
MMD2_k127_4943826_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 306.0
MMD2_k127_4943826_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 309.0
MMD2_k127_4943826_6 PFAM AMP-dependent synthetase and ligase K12508 - 6.2.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000003499 276.0
MMD2_k127_4943826_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000002682 125.0
MMD2_k127_4943826_8 - - - - 0.0004564 50.0
MMD2_k127_5000497_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 521.0
MMD2_k127_5000497_1 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 460.0
MMD2_k127_5000497_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 453.0
MMD2_k127_5000497_3 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 335.0
MMD2_k127_5000497_4 Small Multidrug Resistance protein - - - 0.000000000000000000000000000000000000000000008292 185.0
MMD2_k127_5000497_5 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000001724 144.0
MMD2_k127_5009236_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1335.0
MMD2_k127_5009236_1 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 2.818e-229 723.0
MMD2_k127_5009236_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006326 460.0
MMD2_k127_5009236_3 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 431.0
MMD2_k127_5009236_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 336.0
MMD2_k127_5009236_5 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000008182 239.0
MMD2_k127_5009236_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000001476 179.0
MMD2_k127_5009236_7 Tfp pilus assembly protein K02655 - - 0.00000000000000000000000000000000000005564 149.0
MMD2_k127_5009236_8 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000000003748 132.0
MMD2_k127_5009236_9 Type II transport protein GspH K08084 - - 0.000000000000009319 84.0
MMD2_k127_5039889_0 Thi4 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 466.0
MMD2_k127_5039889_1 trisaccharide binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 373.0
MMD2_k127_5039889_2 Copper binding periplasmic protein CusF - - - 0.00000000000000002303 86.0
MMD2_k127_5042244_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3e-323 996.0
MMD2_k127_5042244_1 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 7.95e-322 993.0
MMD2_k127_5042244_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003949 591.0
MMD2_k127_5042244_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 418.0
MMD2_k127_5042244_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005613 300.0
MMD2_k127_5042244_5 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 312.0
MMD2_k127_5042244_6 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005248 269.0
MMD2_k127_5042244_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002986 235.0
MMD2_k127_5042244_8 Belongs to the UPF0306 family K09979 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000001082 144.0
MMD2_k127_5042244_9 NlpC/P60 family - - - 0.00000000000000000000000000001344 124.0
MMD2_k127_504417_0 PFAM membrane bound O-acyl transferase MBOAT family protein K19294 - - 2.575e-238 743.0
MMD2_k127_504417_1 Transketolase, C-terminal domain K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 579.0
MMD2_k127_504417_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 479.0
MMD2_k127_504417_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000199 264.0
MMD2_k127_504417_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000004799 242.0
MMD2_k127_504417_5 - - - - 0.0000000000000000000000000000002813 127.0
MMD2_k127_504417_6 DoxX K15977 - - 0.0000000000000000000000000003377 120.0
MMD2_k127_5103568_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 454.0
MMD2_k127_5103568_1 Carboxylesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 341.0
MMD2_k127_5103568_2 pyridoxamine 5-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 291.0
MMD2_k127_5103568_3 Transcriptional regulator K07734 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 292.0
MMD2_k127_5103568_4 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002799 270.0
MMD2_k127_5103568_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001048 237.0
MMD2_k127_5103568_6 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000002363 222.0
MMD2_k127_5103568_7 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000008221 143.0
MMD2_k127_5114103_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 6.451e-303 955.0
MMD2_k127_5114103_1 indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 2.997e-228 722.0
MMD2_k127_5114103_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 598.0
MMD2_k127_5114103_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 474.0
MMD2_k127_5114103_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 422.0
MMD2_k127_5114103_5 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007333 284.0
MMD2_k127_5114103_6 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000006561 217.0
MMD2_k127_5172947_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 1.037e-194 658.0
MMD2_k127_5172947_1 Methyl-accepting chemotaxis protein K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 634.0
MMD2_k127_5172947_2 Amino acid amide ABC transporter substrate-binding protein, HAAT family K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 381.0
MMD2_k127_5172947_3 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000003079 242.0
MMD2_k127_5172947_4 RESPONSE REGULATOR receiver K02657 - - 0.00000000000000000000000000000000000000000000000000000002373 201.0
MMD2_k127_5172947_5 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000003285 181.0
MMD2_k127_5172947_6 Chemotaxis signal transduction protein K02659 - - 0.0000000000000000000000000000000000002452 152.0
MMD2_k127_5238763_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1053.0
MMD2_k127_5238763_1 Glucose inhibited division protein A - - - 4.545e-240 752.0
MMD2_k127_5238763_10 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000002112 208.0
MMD2_k127_5238763_11 TIGRFAM iron-sulfur cluster assembly protein IscA K13628 - - 0.000000000000000000000000000000000000000000000000001534 183.0
MMD2_k127_5238763_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000001585 84.0
MMD2_k127_5238763_13 COG1404 Subtilisin-like serine proteases K20755 - 3.4.21.121 0.000000000001625 69.0
MMD2_k127_5238763_2 repeat protein - - - 2.089e-206 653.0
MMD2_k127_5238763_3 Prolyl oligopeptidase family K06889,K19188 - 3.7.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003844 416.0
MMD2_k127_5238763_4 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 349.0
MMD2_k127_5238763_5 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K20755 - 3.4.21.121 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005502 333.0
MMD2_k127_5238763_6 serine acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 306.0
MMD2_k127_5238763_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 302.0
MMD2_k127_5238763_8 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 285.0
MMD2_k127_5238763_9 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.000000000000000000000000000000000000000000000000000000000003014 213.0
MMD2_k127_5361226_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.453e-239 751.0
MMD2_k127_5361226_1 Branched-chain amino acid transport system / permease component K01997,K01998 - - 4.98e-236 746.0
MMD2_k127_5361226_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 578.0
MMD2_k127_5361226_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 475.0
MMD2_k127_5361226_4 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 352.0
MMD2_k127_5361226_5 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 306.0
MMD2_k127_5361226_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005071 311.0
MMD2_k127_5361226_7 - - - - 0.0000005819 55.0
MMD2_k127_5376471_0 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 527.0
MMD2_k127_5376471_1 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 407.0
MMD2_k127_5376471_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 296.0
MMD2_k127_5376471_4 Cytochrome c K17230 - - 0.00000000000000000000000000000000000000000005448 171.0
MMD2_k127_5376471_5 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000004858 148.0
MMD2_k127_541763_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 6.243e-225 708.0
MMD2_k127_541763_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 621.0
MMD2_k127_541763_2 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000447 257.0
MMD2_k127_541763_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000005888 232.0
MMD2_k127_541763_4 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000000000006651 139.0
MMD2_k127_541763_5 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000004418 113.0
MMD2_k127_541763_6 Catalyzes the deformylation of 4-deoxy-4-formamido-L- arabinose-phosphoundecaprenol to 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K13014 GO:0005575,GO:0008150,GO:0010035,GO:0010038,GO:0010039,GO:0010041,GO:0016020,GO:0042221,GO:0050896 - 0.00003723 46.0
MMD2_k127_5515411_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788 - - 0.0 1502.0
MMD2_k127_5515411_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07789 - - 0.0 1442.0
MMD2_k127_5515411_10 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000001567 163.0
MMD2_k127_5515411_11 Domain of unknown function (DUF4154) - - - 0.00000000000000000000000009327 113.0
MMD2_k127_5515411_2 COG1960 Acyl-CoA dehydrogenases K20035 - - 6.403e-254 796.0
MMD2_k127_5515411_3 AMP-binding enzyme C-terminal domain K00666 - - 2.051e-219 688.0
MMD2_k127_5515411_4 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 597.0
MMD2_k127_5515411_5 Periplasmic sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006201 518.0
MMD2_k127_5515411_6 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004432 489.0
MMD2_k127_5515411_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 445.0
MMD2_k127_5515411_8 chemotaxis K03406,K05875 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 399.0
MMD2_k127_5515411_9 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000006747 201.0
MMD2_k127_5517227_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008744 437.0
MMD2_k127_5517227_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006807,GO:0006950,GO:0006979,GO:0008113,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016667,GO:0016671,GO:0019538,GO:0030091,GO:0033744,GO:0036456,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0055114,GO:0071704,GO:1901564 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 336.0
MMD2_k127_5517227_2 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 323.0
MMD2_k127_5517227_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000549 230.0
MMD2_k127_5517227_4 FecR protein - - - 0.00000000000000000000000000000000000000000000000002582 190.0
MMD2_k127_5517227_5 COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) K04762 - - 0.00000000000000000000000000000000002791 148.0
MMD2_k127_5520330_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.292e-283 883.0
MMD2_k127_5520330_1 ATPases associated with a variety of cellular activities K10441 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009131 612.0
MMD2_k127_5520330_10 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000129 213.0
MMD2_k127_5520330_11 Kelch motif - - - 0.00000000000000000000000000000000000000000000002263 196.0
MMD2_k127_5520330_12 Transcriptional regulator - - - 0.000000000000004954 84.0
MMD2_k127_5520330_13 PFAM Fibronectin, type III domain - - - 0.0000000000002734 84.0
MMD2_k127_5520330_14 - - - - 0.0000551 49.0
MMD2_k127_5520330_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 518.0
MMD2_k127_5520330_3 Mediates influx of magnesium ions K03284,K16074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 449.0
MMD2_k127_5520330_4 Periplasmic binding proteins and sugar binding domain of LacI family K10439,K17202,K17205,K17213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 445.0
MMD2_k127_5520330_5 Belongs to the binding-protein-dependent transport system permease family K10440,K10553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 422.0
MMD2_k127_5520330_6 COG0463 Glycosyltransferases involved in cell wall biogenesis K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009781 406.0
MMD2_k127_5520330_7 Belongs to the binding-protein-dependent transport system permease family K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 338.0
MMD2_k127_5520330_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004408 246.0
MMD2_k127_5520330_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001128 253.0
MMD2_k127_5521129_0 chemotaxis K03406,K05875 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 393.0
MMD2_k127_5521129_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 329.0
MMD2_k127_5521129_10 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.0000000000000000000005388 106.0
MMD2_k127_5521129_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001477 268.0
MMD2_k127_5521129_3 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000004166 267.0
MMD2_k127_5521129_4 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004729 267.0
MMD2_k127_5521129_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000002543 235.0
MMD2_k127_5521129_6 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.00000000000000000000000000000000000000000000000000000000000006857 230.0
MMD2_k127_5521129_7 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001204 236.0
MMD2_k127_5521129_8 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000001062 208.0
MMD2_k127_5521129_9 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000001815 197.0
MMD2_k127_553320_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008765 507.0
MMD2_k127_553320_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 404.0
MMD2_k127_553320_2 Alanine racemase, C-terminal domain K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 384.0
MMD2_k127_553320_3 uracil-dna glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 296.0
MMD2_k127_553320_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000003552 143.0
MMD2_k127_554946_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 5.58e-230 726.0
MMD2_k127_554946_1 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 475.0
MMD2_k127_554946_10 - - - - 0.000000000000000000000000000000000000000000000000000000004284 207.0
MMD2_k127_554946_11 Protein conserved in bacteria K09984 - - 0.000000000000000000000000000000000000000000000000000007127 191.0
MMD2_k127_554946_12 protein conserved in bacteria - - - 0.000000000000000000000000000000000004556 142.0
MMD2_k127_554946_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000008182 136.0
MMD2_k127_554946_14 - - - - 0.000000000000004019 79.0
MMD2_k127_554946_15 Serine aminopeptidase, S33 - - - 0.000000006312 57.0
MMD2_k127_554946_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 422.0
MMD2_k127_554946_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 398.0
MMD2_k127_554946_4 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 361.0
MMD2_k127_554946_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 357.0
MMD2_k127_554946_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 303.0
MMD2_k127_554946_7 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001091 245.0
MMD2_k127_554946_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000001351 243.0
MMD2_k127_554946_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001869 243.0
MMD2_k127_5573495_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1421.0
MMD2_k127_5573495_1 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001187 289.0
MMD2_k127_5573495_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002876 273.0
MMD2_k127_5573495_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000003348 236.0
MMD2_k127_5573495_4 Phasin protein - - - 0.00000000000000000000000000000000000000000000004583 176.0
MMD2_k127_5573495_5 Etoposide-induced protein 2.4 (EI24) - - - 0.000000000000000000000000000000000000000001138 165.0
MMD2_k127_5573495_6 FecR protein - - - 0.000000000000000000000000000004451 132.0
MMD2_k127_55858_0 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 3.587e-292 916.0
MMD2_k127_55858_1 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 4.232e-276 857.0
MMD2_k127_55858_2 COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 4.959e-265 824.0
MMD2_k127_55858_3 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006257 480.0
MMD2_k127_55858_4 Dienelactone hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003531 340.0
MMD2_k127_55858_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 338.0
MMD2_k127_55858_6 (ABC) transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 334.0
MMD2_k127_55858_7 membrane - - - 0.0000000000000000000000000000000000000003109 152.0
MMD2_k127_55858_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000007253 144.0
MMD2_k127_55858_9 Thioesterase superfamily K07107 - - 0.000000000000000000000000000003188 139.0
MMD2_k127_5587292_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1145.0
MMD2_k127_5587292_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1116.0
MMD2_k127_5587292_10 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003845 436.0
MMD2_k127_5587292_11 extracellular solute-binding protein, family 5 K02035,K15584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 387.0
MMD2_k127_5587292_12 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 351.0
MMD2_k127_5587292_13 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 334.0
MMD2_k127_5587292_14 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 297.0
MMD2_k127_5587292_15 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 295.0
MMD2_k127_5587292_16 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000165 275.0
MMD2_k127_5587292_17 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004188 243.0
MMD2_k127_5587292_18 Virulence factor membrane-bound polymerase, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000001046 245.0
MMD2_k127_5587292_19 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000002617 207.0
MMD2_k127_5587292_2 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1088.0
MMD2_k127_5587292_20 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000003446 206.0
MMD2_k127_5587292_21 sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000001096 173.0
MMD2_k127_5587292_22 oxidation protein K17227 - - 0.0000000000000000000000000000006667 124.0
MMD2_k127_5587292_23 WD40-like Beta Propeller Repeat K03641,K08676 - - 0.0000000000000000002691 103.0
MMD2_k127_5587292_24 - - - - 0.00000005186 58.0
MMD2_k127_5587292_25 macromolecule glycosylation - GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000623 55.0
MMD2_k127_5587292_26 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00001099 59.0
MMD2_k127_5587292_3 CHASE2 K01768 - 4.6.1.1 1.378e-266 841.0
MMD2_k127_5587292_4 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 3.997e-263 820.0
MMD2_k127_5587292_5 O-linked N-acetylglucosamine transferase, SPINDLY family - - - 2.302e-225 745.0
MMD2_k127_5587292_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 2.418e-221 699.0
MMD2_k127_5587292_7 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 1.355e-213 668.0
MMD2_k127_5587292_8 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 518.0
MMD2_k127_5587292_9 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 450.0
MMD2_k127_5590336_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 2.549e-279 865.0
MMD2_k127_5590336_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 2.743e-211 669.0
MMD2_k127_5590336_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 308.0
MMD2_k127_5590336_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000008894 88.0
MMD2_k127_5598413_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1194.0
MMD2_k127_5598413_1 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 8.847e-221 690.0
MMD2_k127_5598413_10 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000002283 161.0
MMD2_k127_5598413_11 Cold shock protein K03704 - - 0.00000000000000000000000000000000002129 137.0
MMD2_k127_5598413_12 - - - - 0.000000000000000000000000000008783 132.0
MMD2_k127_5598413_2 Sulfate permease family K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 548.0
MMD2_k127_5598413_3 sulfide dehydrogenase K05301 - 1.8.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 446.0
MMD2_k127_5598413_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 376.0
MMD2_k127_5598413_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 284.0
MMD2_k127_5598413_6 Urate oxidase N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001627 254.0
MMD2_k127_5598413_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000000000000000008237 234.0
MMD2_k127_5598413_8 to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000463 200.0
MMD2_k127_5598413_9 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000000000000000000000000000001784 173.0
MMD2_k127_5605310_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.893e-293 913.0
MMD2_k127_5605310_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 493.0
MMD2_k127_5605310_2 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 496.0
MMD2_k127_5605310_3 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 454.0
MMD2_k127_5605310_4 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 382.0
MMD2_k127_5605310_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 307.0
MMD2_k127_5605310_6 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004264 281.0
MMD2_k127_5605310_7 atpase or kinase K06925 - - 0.000000000000000000000000000000000000000000000009762 175.0
MMD2_k127_5605310_8 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000002817 120.0
MMD2_k127_5605310_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000418 85.0
MMD2_k127_5619787_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 2.389e-292 937.0
MMD2_k127_5619787_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 5.537e-240 745.0
MMD2_k127_5619787_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.391e-219 717.0
MMD2_k127_5619787_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 515.0
MMD2_k127_5619787_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004565 248.0
MMD2_k127_5619787_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000252 154.0
MMD2_k127_5701923_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1594.0
MMD2_k127_5701923_1 Molecular chaperone. Has ATPase activity K04079 - - 1.239e-304 951.0
MMD2_k127_5701923_10 Rhodanese domain protein - - - 0.000000000000000000000000000000001371 132.0
MMD2_k127_5701923_11 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000104 94.0
MMD2_k127_5701923_2 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 493.0
MMD2_k127_5701923_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 305.0
MMD2_k127_5701923_4 Transcriptional regulator K18954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 296.0
MMD2_k127_5701923_5 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001241 275.0
MMD2_k127_5701923_6 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001895 266.0
MMD2_k127_5701923_7 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001215 259.0
MMD2_k127_5701923_8 Chaperone - - - 0.0000000000000000000000000000000000000000000000000004023 192.0
MMD2_k127_5701923_9 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000001398 197.0
MMD2_k127_5708120_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 559.0
MMD2_k127_5708120_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000652 333.0
MMD2_k127_5708120_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000006014 200.0
MMD2_k127_5708120_3 TonB C terminal K03646 - - 0.0000000000000000000000000000000000000000000004316 179.0
MMD2_k127_5708120_4 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000005383 141.0
MMD2_k127_5708120_5 Acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000001882 138.0
MMD2_k127_5726100_0 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 492.0
MMD2_k127_5726100_1 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004168 389.0
MMD2_k127_5726100_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 381.0
MMD2_k127_5726100_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 378.0
MMD2_k127_5726100_4 abc transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 308.0
MMD2_k127_5726100_5 abc transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001809 256.0
MMD2_k127_5732741_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.182e-257 803.0
MMD2_k127_5732741_1 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 1.492e-225 730.0
MMD2_k127_5732741_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 383.0
MMD2_k127_5732741_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 361.0
MMD2_k127_5732741_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 326.0
MMD2_k127_5732741_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000008624 220.0
MMD2_k127_5732741_6 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000000005756 184.0
MMD2_k127_5732741_7 LysM domain protein - - - 0.000000000000000000000000393 109.0
MMD2_k127_5770340_0 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 4.407e-199 625.0
MMD2_k127_5770340_1 Extracellular liganD-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005664 472.0
MMD2_k127_5770340_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003938 285.0
MMD2_k127_5772664_0 Elongator protein 3, MiaB family, Radical SAM - - - 1e-323 1000.0
MMD2_k127_5772664_1 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 499.0
MMD2_k127_5772664_2 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009429 355.0
MMD2_k127_5772664_3 ZIP Zinc transporter K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 344.0
MMD2_k127_5772664_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 343.0
MMD2_k127_5772664_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 328.0
MMD2_k127_5772664_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 287.0
MMD2_k127_5772664_7 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000004142 262.0
MMD2_k127_5772664_8 Acyl carrier protein phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002354 263.0
MMD2_k127_5782097_0 Domain of unknown function (DUF4131) K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000755 440.0
MMD2_k127_5782097_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 337.0
MMD2_k127_5782097_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008147 294.0
MMD2_k127_5782097_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 291.0
MMD2_k127_5782097_4 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004465 269.0
MMD2_k127_5782097_5 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000024 185.0
MMD2_k127_5782097_6 TPM domain - - - 0.00000000000000000000000000000000000000000000000003499 186.0
MMD2_k127_5782097_7 Transmembrane secretion effector - - - 0.0000000000000000003864 101.0
MMD2_k127_5782168_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1057.0
MMD2_k127_5782168_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1054.0
MMD2_k127_5782168_10 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 293.0
MMD2_k127_5782168_11 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 297.0
MMD2_k127_5782168_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001865 276.0
MMD2_k127_5782168_13 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001265 268.0
MMD2_k127_5782168_14 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 255.0
MMD2_k127_5782168_15 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000008582 256.0
MMD2_k127_5782168_16 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000028 239.0
MMD2_k127_5782168_17 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
MMD2_k127_5782168_18 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000003397 169.0
MMD2_k127_5782168_19 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000006388 152.0
MMD2_k127_5782168_2 Participates in both transcription termination and antitermination K02600 - - 1.33e-228 717.0
MMD2_k127_5782168_20 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000001635 133.0
MMD2_k127_5782168_21 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000001733 128.0
MMD2_k127_5782168_22 - - - - 0.0000000000000000006731 90.0
MMD2_k127_5782168_23 FecR protein - - - 0.00000000006553 72.0
MMD2_k127_5782168_3 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 5.663e-212 663.0
MMD2_k127_5782168_4 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 555.0
MMD2_k127_5782168_5 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 529.0
MMD2_k127_5782168_6 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 477.0
MMD2_k127_5782168_7 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 434.0
MMD2_k127_5782168_8 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 425.0
MMD2_k127_5782168_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 332.0
MMD2_k127_5809553_0 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 494.0
MMD2_k127_5809553_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 384.0
MMD2_k127_5809553_2 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 328.0
MMD2_k127_5809553_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000002515 236.0
MMD2_k127_5809553_4 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000000001699 177.0
MMD2_k127_5809553_5 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000001204 131.0
MMD2_k127_5809553_6 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000001457 102.0
MMD2_k127_5809553_7 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000317 64.0
MMD2_k127_5809553_8 Pfam:DUF1602 - - - 0.00001595 48.0
MMD2_k127_5809553_9 Pfam:DUF1602 - - - 0.00009331 47.0
MMD2_k127_5853357_0 Glycosyl Transferase - - - 1.844e-196 646.0
MMD2_k127_5853357_1 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 499.0
MMD2_k127_5853357_2 Phenazine biosynthesis-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 337.0
MMD2_k127_5853357_3 regulator K18831 - - 0.0000000000000000000000000000000000000000000001169 171.0
MMD2_k127_5853357_4 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000000000000000000000000000002046 154.0
MMD2_k127_5853357_5 - - - - 0.0000000000000000000000000000004256 132.0
MMD2_k127_5853357_6 Protein of unknown function (DUF433) - - - 0.00000000000000000000000205 103.0
MMD2_k127_5853357_7 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000002677 100.0
MMD2_k127_5853357_8 hydrolase or acyltransferase of alpha beta superfamily - - - 0.00000000000000002572 85.0
MMD2_k127_5853357_9 Predicted membrane protein (DUF2238) - - - 0.00000000000003137 83.0
MMD2_k127_5862678_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 503.0
MMD2_k127_5862678_1 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 465.0
MMD2_k127_5862678_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005943 289.0
MMD2_k127_5862678_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006996 252.0
MMD2_k127_5862678_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000001651 147.0
MMD2_k127_5862678_5 Putative zinc ribbon domain - - - 0.00000000000000000000002266 101.0
MMD2_k127_586827_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 536.0
MMD2_k127_586827_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 392.0
MMD2_k127_586827_2 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 373.0
MMD2_k127_586827_3 RNA polymerase sigma factor, sigma-70 family K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 354.0
MMD2_k127_586827_4 oxidase assembly K02258 - - 0.000000000000000000000000000000000000000000000000000000000000000003332 232.0
MMD2_k127_586827_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000009469 219.0
MMD2_k127_586827_6 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000000000001337 194.0
MMD2_k127_586827_7 signal sequence binding - - - 0.000000000000000000000000000000000000000003569 162.0
MMD2_k127_586827_8 Protein of unknown function (DUF2909) - - - 0.00000002131 61.0
MMD2_k127_5886076_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 8.096e-217 680.0
MMD2_k127_5886076_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004102 549.0
MMD2_k127_5886076_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 390.0
MMD2_k127_5886076_3 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 359.0
MMD2_k127_5886076_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 325.0
MMD2_k127_5886076_5 synthesis repressor, PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006014 254.0
MMD2_k127_5886076_6 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000004795 222.0
MMD2_k127_5950788_0 Catalyzes the formation of arginine from (N-L-arginino)succinate K01755 - 4.3.2.1 5.962e-211 664.0
MMD2_k127_5950788_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 526.0
MMD2_k127_5950788_10 YfaZ precursor - - - 0.0000000000001737 79.0
MMD2_k127_5950788_11 Histidine kinase K08082 - 2.7.13.3 0.0000001454 55.0
MMD2_k127_5950788_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K16079,K22110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 524.0
MMD2_k127_5950788_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 524.0
MMD2_k127_5950788_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 522.0
MMD2_k127_5950788_5 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 497.0
MMD2_k127_5950788_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 395.0
MMD2_k127_5950788_7 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000409 265.0
MMD2_k127_5950788_8 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000001803 172.0
MMD2_k127_5950788_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000001075 94.0
MMD2_k127_5954024_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 605.0
MMD2_k127_5954024_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 383.0
MMD2_k127_5954024_2 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008714 344.0
MMD2_k127_5954024_3 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 273.0
MMD2_k127_5954024_4 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000000000006508 232.0
MMD2_k127_5954024_5 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000000000000000000001855 199.0
MMD2_k127_5954024_6 coa-binding K06929 - - 0.000000000000000000000000000000000000000000002863 170.0
MMD2_k127_5990131_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009514 462.0
MMD2_k127_5990131_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 398.0
MMD2_k127_5990131_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 332.0
MMD2_k127_5990131_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 304.0
MMD2_k127_5990131_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006228 270.0
MMD2_k127_5990131_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000002147 214.0
MMD2_k127_5990131_6 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000000000007287 149.0
MMD2_k127_5990131_7 Pyridoxamine 5'-phosphate oxidase - - - 0.000000000000000000000000000000000009444 143.0
MMD2_k127_5990131_8 - - - - 0.00000000000000000000002661 106.0
MMD2_k127_5990131_9 Antibiotic biosynthesis monooxygenase - - - 0.000000000000003705 79.0
MMD2_k127_6003659_0 Histidine kinase K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 461.0
MMD2_k127_6003659_1 dihydrofolate reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 347.0
MMD2_k127_6003659_10 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000001336 179.0
MMD2_k127_6003659_11 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000127 136.0
MMD2_k127_6003659_12 Phosphoglycerate mutase family - - - 0.0000000000000000000000000000000006421 139.0
MMD2_k127_6003659_13 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000009086 98.0
MMD2_k127_6003659_2 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007262 287.0
MMD2_k127_6003659_3 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001615 265.0
MMD2_k127_6003659_4 Glutathione-dependent formaldehyde-activating - - - 0.000000000000000000000000000000000000000000000000000000000000000000008091 235.0
MMD2_k127_6003659_5 YCII-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
MMD2_k127_6003659_6 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000009104 226.0
MMD2_k127_6003659_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.0000000000000000000000000000000000000000000000000000000007728 205.0
MMD2_k127_6003659_8 3-demethylubiquinone-9 3-methyltransferase K04750 - - 0.000000000000000000000000000000000000000000000000000001671 196.0
MMD2_k127_6003659_9 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000000000000006366 193.0
MMD2_k127_6019404_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K03520,K11177 - 1.17.1.4,1.2.5.3 0.0 1288.0
MMD2_k127_6019404_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 612.0
MMD2_k127_6019404_10 Bacterial regulatory proteins, tetR family K05501 - - 0.0000000000000000000000000000000000000000000000000000000000003332 218.0
MMD2_k127_6019404_11 MaoC like domain - - - 0.0000000000000000000000000000000000000000000000001333 185.0
MMD2_k127_6019404_12 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000005581 190.0
MMD2_k127_6019404_13 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000004122 166.0
MMD2_k127_6019404_14 Peptidase family M23 - - - 0.00000000000000000000000000000000000000001716 155.0
MMD2_k127_6019404_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 436.0
MMD2_k127_6019404_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 353.0
MMD2_k127_6019404_4 AAA domain (dynein-related subfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 347.0
MMD2_k127_6019404_5 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005536 334.0
MMD2_k127_6019404_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003158 312.0
MMD2_k127_6019404_7 Pyrimidine 5''-nucleotidase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005253 251.0
MMD2_k127_6019404_8 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000001417 252.0
MMD2_k127_6019404_9 Protein containing von Willebrand factor type A (vWA) domain K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000009502 232.0
MMD2_k127_6037660_0 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009388 399.0
MMD2_k127_6037660_1 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 318.0
MMD2_k127_6037660_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003229 284.0
MMD2_k127_6037660_3 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003273 265.0
MMD2_k127_6046734_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 4.167e-207 668.0
MMD2_k127_6046734_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003715 452.0
MMD2_k127_6046734_10 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000000000000593 134.0
MMD2_k127_6046734_2 CoA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 377.0
MMD2_k127_6046734_3 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 370.0
MMD2_k127_6046734_4 PFAM glycosyl transferase family 4 K13007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003625 273.0
MMD2_k127_6046734_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000002129 213.0
MMD2_k127_6046734_6 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000001818 196.0
MMD2_k127_6046734_7 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000004625 192.0
MMD2_k127_6046734_8 SMART phosphoesterase PA-phosphatase related - - - 0.000000000000000000000000000000000000003544 156.0
MMD2_k127_6046734_9 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000000000000000000000000000000001314 153.0
MMD2_k127_6057208_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0 1106.0
MMD2_k127_6057208_1 4 iron, 4 sulfur cluster binding - - - 3.606e-239 752.0
MMD2_k127_6057208_2 CoA-substrate-specific enzyme activase - - - 1.462e-202 638.0
MMD2_k127_6057208_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 469.0
MMD2_k127_6057208_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 400.0
MMD2_k127_6057208_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 343.0
MMD2_k127_6063008_0 acyl-CoA dehydrogenase K06445 - - 1.986e-320 1012.0
MMD2_k127_6063008_1 ABC transporter transmembrane region K06147 - - 1.642e-242 764.0
MMD2_k127_6063008_2 Belongs to the thiolase family K00626 - 2.3.1.9 1.738e-199 640.0
MMD2_k127_6063008_3 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 495.0
MMD2_k127_6063008_4 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006013 286.0
MMD2_k127_6063008_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000939 231.0
MMD2_k127_6063008_6 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000003155 151.0
MMD2_k127_6082448_0 TonB-dependent receptor K02014 - - 2.834e-197 653.0
MMD2_k127_6082448_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000672 597.0
MMD2_k127_6082448_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004603 312.0
MMD2_k127_6082448_11 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000000009799 199.0
MMD2_k127_6082448_12 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000004565 168.0
MMD2_k127_6082448_13 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000000000000000001841 164.0
MMD2_k127_6082448_14 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.000000000000000000000000000000001044 133.0
MMD2_k127_6082448_15 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000659 125.0
MMD2_k127_6082448_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000009371 117.0
MMD2_k127_6082448_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000003136 106.0
MMD2_k127_6082448_2 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 419.0
MMD2_k127_6082448_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 409.0
MMD2_k127_6082448_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 420.0
MMD2_k127_6082448_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 380.0
MMD2_k127_6082448_6 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000146 383.0
MMD2_k127_6082448_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 343.0
MMD2_k127_6082448_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 329.0
MMD2_k127_6082448_9 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 342.0
MMD2_k127_6082995_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.277e-243 762.0
MMD2_k127_6082995_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 513.0
MMD2_k127_6082995_10 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 305.0
MMD2_k127_6082995_11 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000006135 260.0
MMD2_k127_6082995_12 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007554 250.0
MMD2_k127_6082995_13 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000005187 243.0
MMD2_k127_6082995_14 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000000000001681 247.0
MMD2_k127_6082995_15 Peptidoglycan-synthase activator LpoB K07337 - - 0.000000000000000000000000000000000000000000000000000000000000000001914 232.0
MMD2_k127_6082995_16 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000001892 226.0
MMD2_k127_6082995_17 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000001426 216.0
MMD2_k127_6082995_18 - - - - 0.00000000000000000000000000000000000000004906 159.0
MMD2_k127_6082995_19 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000008819 138.0
MMD2_k127_6082995_2 methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 482.0
MMD2_k127_6082995_20 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000002514 135.0
MMD2_k127_6082995_21 Rubrerythrin - - - 0.000000000000000000001126 102.0
MMD2_k127_6082995_22 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000006212 108.0
MMD2_k127_6082995_23 LPP20 lipoprotein - - - 0.000000000000000001632 97.0
MMD2_k127_6082995_24 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000003194 74.0
MMD2_k127_6082995_25 COG3325 Chitinase K01183 - 3.2.1.14 0.00000000951 68.0
MMD2_k127_6082995_26 DoxX K15977 - - 0.000003941 55.0
MMD2_k127_6082995_3 Ecdysteroid kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 470.0
MMD2_k127_6082995_4 protein conserved in bacteria K09859 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 402.0
MMD2_k127_6082995_5 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 392.0
MMD2_k127_6082995_6 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 394.0
MMD2_k127_6082995_7 abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 370.0
MMD2_k127_6082995_8 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 365.0
MMD2_k127_6082995_9 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 303.0
MMD2_k127_6123732_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1026.0
MMD2_k127_6123732_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004376 248.0
MMD2_k127_6123732_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000005439 212.0
MMD2_k127_6123732_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000000000000000000003018 184.0
MMD2_k127_6123732_4 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000009055 137.0
MMD2_k127_6123732_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000005875 96.0
MMD2_k127_6123732_6 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000003645 91.0
MMD2_k127_6123732_7 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000006057 49.0
MMD2_k127_6125749_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.65e-232 733.0
MMD2_k127_6125749_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 612.0
MMD2_k127_6125749_10 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005026 331.0
MMD2_k127_6125749_11 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 296.0
MMD2_k127_6125749_12 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 265.0
MMD2_k127_6125749_13 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001988 267.0
MMD2_k127_6125749_14 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000157 277.0
MMD2_k127_6125749_15 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000000000003512 243.0
MMD2_k127_6125749_16 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000009255 250.0
MMD2_k127_6125749_17 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000376 222.0
MMD2_k127_6125749_18 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000005771 211.0
MMD2_k127_6125749_19 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000353 206.0
MMD2_k127_6125749_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 588.0
MMD2_k127_6125749_20 Rubredoxin - - - 0.00000000000000000000000000000004736 125.0
MMD2_k127_6125749_21 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000009612 115.0
MMD2_k127_6125749_22 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000002096 118.0
MMD2_k127_6125749_3 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 538.0
MMD2_k127_6125749_4 Protein involved in ribonuclease activity and hydrolase activity K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 541.0
MMD2_k127_6125749_5 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
MMD2_k127_6125749_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 467.0
MMD2_k127_6125749_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 470.0
MMD2_k127_6125749_8 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 422.0
MMD2_k127_6125749_9 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 382.0
MMD2_k127_6142595_0 Malic enzyme K00029 - 1.1.1.40 0.0 1089.0
MMD2_k127_6142595_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 5.422e-265 827.0
MMD2_k127_6142595_10 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000841 402.0
MMD2_k127_6142595_11 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 396.0
MMD2_k127_6142595_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 366.0
MMD2_k127_6142595_13 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406,K05874 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 360.0
MMD2_k127_6142595_14 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 333.0
MMD2_k127_6142595_15 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 293.0
MMD2_k127_6142595_16 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 314.0
MMD2_k127_6142595_17 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005521 278.0
MMD2_k127_6142595_18 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007681 257.0
MMD2_k127_6142595_19 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000009332 267.0
MMD2_k127_6142595_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 3.194e-261 816.0
MMD2_k127_6142595_20 PFAM Lytic transglycosylase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001194 256.0
MMD2_k127_6142595_21 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006616 243.0
MMD2_k127_6142595_22 N-acetylmuramoyl-L-alanine amidase K03806 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000812 238.0
MMD2_k127_6142595_23 COG0739 Membrane proteins related to metalloendopeptidases K06194 - - 0.0000000000000000000000000000000000000000000000000000000000000000001447 252.0
MMD2_k127_6142595_24 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000003899 152.0
MMD2_k127_6142595_25 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) - - - 0.0000000000000000000000000000000000006527 150.0
MMD2_k127_6142595_26 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0001558,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040008,GO:0042254,GO:0042255,GO:0042256,GO:0042273,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044087,GO:0044089,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048518,GO:0050789,GO:0050794,GO:0051128,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090069,GO:0090070,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000000000000000002968 130.0
MMD2_k127_6142595_27 - - - - 0.000000000000000000008885 104.0
MMD2_k127_6142595_28 - K06950 - - 0.00000000001147 67.0
MMD2_k127_6142595_29 Protein of unknown function (DUF2442) - - - 0.00000000005372 66.0
MMD2_k127_6142595_3 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 - 1.17.4.1 7.51e-209 653.0
MMD2_k127_6142595_30 Histone H1-like nucleoprotein HC2 K11275 - - 0.0000000005772 64.0
MMD2_k127_6142595_4 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 5.452e-203 636.0
MMD2_k127_6142595_5 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 560.0
MMD2_k127_6142595_6 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009193 570.0
MMD2_k127_6142595_7 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 515.0
MMD2_k127_6142595_8 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 491.0
MMD2_k127_6142595_9 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 409.0
MMD2_k127_615498_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0 1073.0
MMD2_k127_615498_1 Predicted membrane protein (DUF2339) - - - 1.873e-266 848.0
MMD2_k127_615498_10 PFAM Metallophosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004162 277.0
MMD2_k127_615498_11 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002919 256.0
MMD2_k127_615498_12 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000001579 220.0
MMD2_k127_615498_13 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000009948 190.0
MMD2_k127_615498_14 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000001423 188.0
MMD2_k127_615498_15 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000001971 176.0
MMD2_k127_615498_16 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000003519 143.0
MMD2_k127_615498_17 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000008748 139.0
MMD2_k127_615498_18 Rieske-like [2Fe-2S] domain K00363 - 1.7.1.15 0.00000000000000000000000000005052 133.0
MMD2_k127_615498_19 - - - - 0.0000000000000000007544 97.0
MMD2_k127_615498_2 nitrite reductase NAD(P)H K00362,K05297 - 1.18.1.1,1.7.1.15 1.438e-257 801.0
MMD2_k127_615498_20 Trypsin-like peptidase domain - - - 0.00000000000005767 83.0
MMD2_k127_615498_21 - - - - 0.0000000000003162 79.0
MMD2_k127_615498_3 ribonuclease, Rne Rng family K08301 - - 2.69e-230 721.0
MMD2_k127_615498_4 Belongs to the amidase family K01426 - 3.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 601.0
MMD2_k127_615498_5 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000807 556.0
MMD2_k127_615498_6 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 514.0
MMD2_k127_615498_7 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 364.0
MMD2_k127_615498_8 Protein of unknown function (DUF3999) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 377.0
MMD2_k127_615498_9 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 337.0
MMD2_k127_6155883_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.911e-245 766.0
MMD2_k127_6155883_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 2.053e-230 717.0
MMD2_k127_6155883_10 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003915 385.0
MMD2_k127_6155883_11 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 339.0
MMD2_k127_6155883_12 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001145 271.0
MMD2_k127_6155883_13 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000007909 260.0
MMD2_k127_6155883_14 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000006339 254.0
MMD2_k127_6155883_15 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000003268 243.0
MMD2_k127_6155883_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000002956 216.0
MMD2_k127_6155883_17 Psort location CytoplasmicMembrane, score K03558 - - 0.000000000000000000000000001373 119.0
MMD2_k127_6155883_18 Sporulation related domain K03749 - - 0.00000000000000002618 90.0
MMD2_k127_6155883_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.42e-204 646.0
MMD2_k127_6155883_3 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 558.0
MMD2_k127_6155883_4 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 539.0
MMD2_k127_6155883_5 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 524.0
MMD2_k127_6155883_6 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 476.0
MMD2_k127_6155883_7 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 462.0
MMD2_k127_6155883_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 454.0
MMD2_k127_6155883_9 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 412.0
MMD2_k127_6222201_0 abc transporter K15738 - - 1.962e-204 647.0
MMD2_k127_6222201_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 522.0
MMD2_k127_6222201_10 - - - - 0.0000000000000000001515 98.0
MMD2_k127_6222201_12 PFAM periplasmic solute binding protein K02077 - - 0.000009026 49.0
MMD2_k127_6222201_13 - - - - 0.0002127 46.0
MMD2_k127_6222201_2 Sugar (and other) transporter K08369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 479.0
MMD2_k127_6222201_3 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 449.0
MMD2_k127_6222201_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 360.0
MMD2_k127_6222201_5 glycosyl transferase K20444 - - 0.000000000000000000000000000000000000000000000000000000000000000000008327 245.0
MMD2_k127_6222201_6 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000009738 207.0
MMD2_k127_6222201_7 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000001234 195.0
MMD2_k127_6222201_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000001356 115.0
MMD2_k127_6222201_9 cytochrome c5 - - - 0.000000000000000000001572 104.0
MMD2_k127_6223152_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 542.0
MMD2_k127_6223152_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 411.0
MMD2_k127_6223152_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 400.0
MMD2_k127_6223152_3 methyl-accepting chemotaxis K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 379.0
MMD2_k127_6223152_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007133 286.0
MMD2_k127_6223152_5 Branched-chain amino acid ATP-binding cassette transporter - - - 0.0000000000000000000000000000000000000000000000000000000000002131 231.0
MMD2_k127_6223152_6 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000319 151.0
MMD2_k127_6223152_7 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000554 125.0
MMD2_k127_6224154_0 Tripartite tricarboxylate transporter TctA family - - - 2.119e-230 722.0
MMD2_k127_6224154_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K00446 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 384.0
MMD2_k127_6224154_2 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 311.0
MMD2_k127_6224154_3 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000416 288.0
MMD2_k127_6224154_4 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000251 235.0
MMD2_k127_6224154_5 protein conserved in bacteria K09931 - - 0.00000000000000000000000000000000000000000005454 169.0
MMD2_k127_6224154_6 Tripartite tricarboxylate transporter TctB family - - - 0.0000000000000000000000000001013 121.0
MMD2_k127_6224154_7 Glycosyl transferase family 2 - - - 0.000000000000003979 75.0
MMD2_k127_6224154_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000001783 52.0
MMD2_k127_6236369_0 Phospholipase D. Active site motifs. - - - 5.946e-194 615.0
MMD2_k127_6236369_1 PFAM CHASE2 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000245 302.0
MMD2_k127_6236369_2 MgtC family K07507 - - 0.00000000000000000000000000000000000000000000000000000000000000000001585 247.0
MMD2_k127_6236369_3 PFAM thioesterase superfamily protein - - - 0.0000000000000000000002443 102.0
MMD2_k127_6237799_0 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 445.0
MMD2_k127_6237799_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 431.0
MMD2_k127_6237799_10 gluconolactonase activity - - - 0.00000000000000000000006116 112.0
MMD2_k127_6237799_11 VIT family - - - 0.000004927 49.0
MMD2_k127_6237799_2 Transcriptional regulator K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007787 390.0
MMD2_k127_6237799_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006999 325.0
MMD2_k127_6237799_4 SMART transcription factor jumonji jmjC K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001838 310.0
MMD2_k127_6237799_5 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001303 267.0
MMD2_k127_6237799_6 NlpB/DapX lipoprotein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000002856 260.0
MMD2_k127_6237799_7 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000001766 216.0
MMD2_k127_6237799_8 Bacterial protein of unknown function (DUF899) K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000415 212.0
MMD2_k127_6237799_9 - - - - 0.00000000000000000000000002344 115.0
MMD2_k127_6242983_0 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 282.0
MMD2_k127_6242983_1 Sigma-70, region 4 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000665 268.0
MMD2_k127_6242983_2 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000005435 224.0
MMD2_k127_6242983_3 - - - - 0.0000000000000000000000000000000000000000000000000000002397 200.0
MMD2_k127_6242983_4 tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000001126 195.0
MMD2_k127_6242983_5 - - - - 0.00000000000000001191 85.0
MMD2_k127_6243341_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.599e-297 921.0
MMD2_k127_6243341_1 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 557.0
MMD2_k127_6243341_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 509.0
MMD2_k127_6243341_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003675 299.0
MMD2_k127_6243341_4 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000008031 149.0
MMD2_k127_6243341_5 - - - - 0.000000000000000000000001318 108.0
MMD2_k127_6243341_6 - - - - 0.00000000000000007545 85.0
MMD2_k127_6243341_7 LysM domain protein - - - 0.0000000166 68.0
MMD2_k127_6248233_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1274.0
MMD2_k127_6248233_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 590.0
MMD2_k127_6248233_10 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001757 349.0
MMD2_k127_6248233_11 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 342.0
MMD2_k127_6248233_12 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 338.0
MMD2_k127_6248233_13 Peptidase family M23 K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
MMD2_k127_6248233_14 PFAM Cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001711 280.0
MMD2_k127_6248233_15 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000001653 239.0
MMD2_k127_6248233_16 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000004282 196.0
MMD2_k127_6248233_17 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000000000001287 145.0
MMD2_k127_6248233_18 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000001072 123.0
MMD2_k127_6248233_19 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000001038 81.0
MMD2_k127_6248233_2 type II secretion system protein K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 584.0
MMD2_k127_6248233_20 Protein conserved in bacteria - - - 0.000000002481 65.0
MMD2_k127_6248233_3 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003787 544.0
MMD2_k127_6248233_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 518.0
MMD2_k127_6248233_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 492.0
MMD2_k127_6248233_6 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006216 450.0
MMD2_k127_6248233_7 Domain of unknown function DUF21 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 447.0
MMD2_k127_6248233_8 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 386.0
MMD2_k127_6248233_9 ATPase (AAA K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 392.0
MMD2_k127_6272398_0 Histidine kinase K20974 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 580.0
MMD2_k127_6272398_1 Amidohydrolase K10220 - 4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 470.0
MMD2_k127_6272398_2 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003822 345.0
MMD2_k127_6272398_3 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 312.0
MMD2_k127_6272398_4 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 289.0
MMD2_k127_6272398_5 - - - - 0.0000000000000000000000000000000004388 135.0
MMD2_k127_6272398_6 sulfur oxidation protein (SoxY) K17226 - - 0.000000000000000000000000000000001739 136.0
MMD2_k127_6272398_7 cytochrome c K17223 - - 0.00000000000000000000000000000001117 133.0
MMD2_k127_6272398_8 Sulphur oxidation protein SoxZ K17227 - - 0.00000000000000000000000000009699 119.0
MMD2_k127_6272398_9 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 0.0000000000000000001393 89.0
MMD2_k127_6273139_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520 - 1.2.5.3 0.0 1052.0
MMD2_k127_6273139_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 551.0
MMD2_k127_6273139_2 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007786 454.0
MMD2_k127_6273139_3 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 417.0
MMD2_k127_6273139_4 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000338 224.0
MMD2_k127_6273139_5 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000001456 137.0
MMD2_k127_6275046_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 340.0
MMD2_k127_6275046_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 327.0
MMD2_k127_6275046_2 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000001363 236.0
MMD2_k127_6275046_3 Fumarate reductase subunit C - - - 0.000000000000000000000000000000001395 136.0
MMD2_k127_6275046_4 Preprotein translocase subunit SecG K03075 - - 0.00000000000000000000000000007933 119.0
MMD2_k127_6275046_5 Fumarate reductase subunit D - - - 0.000000000000000007942 88.0
MMD2_k127_6275046_6 Fumarate reductase flavoprotein C-term K00244 - 1.3.5.4 0.00000004551 55.0
MMD2_k127_679838_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 6.053e-294 922.0
MMD2_k127_679838_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 499.0
MMD2_k127_679838_2 TIGRFAM cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 378.0
MMD2_k127_679838_3 heptosyltransferase II K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 340.0
MMD2_k127_679838_4 Zinc-finger domain - - - 0.000000000000000000003228 106.0
MMD2_k127_711401_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 586.0
MMD2_k127_711401_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 501.0
MMD2_k127_711401_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000000002572 195.0
MMD2_k127_711401_11 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000005135 188.0
MMD2_k127_711401_12 protein involved in tolerance to divalent cations K03926 - - 0.00000000000000000000000000000000000001764 150.0
MMD2_k127_711401_13 PFAM cytochrome c - - - 0.000000000000000000000000000009143 123.0
MMD2_k127_711401_2 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 492.0
MMD2_k127_711401_3 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 442.0
MMD2_k127_711401_4 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 289.0
MMD2_k127_711401_5 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002877 267.0
MMD2_k127_711401_6 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002635 254.0
MMD2_k127_711401_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000001724 239.0
MMD2_k127_711401_8 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000000000000000844 233.0
MMD2_k127_711401_9 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000003405 203.0
MMD2_k127_739305_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1622.0
MMD2_k127_739305_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 5.2e-233 724.0
MMD2_k127_739305_2 Uncharacterized protein family (UPF0051) K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 606.0
MMD2_k127_739305_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 456.0
MMD2_k127_739305_4 PFAM DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 345.0
MMD2_k127_739305_5 ABC transporter K09013 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 328.0
MMD2_k127_739305_6 Scaffold protein Nfu/NifU N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 305.0
MMD2_k127_739305_7 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003418 269.0
MMD2_k127_739305_8 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003413 270.0
MMD2_k127_741159_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 1.13e-209 672.0
MMD2_k127_741159_1 Carbohydrate-selective porin, OprB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 532.0
MMD2_k127_741159_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007298 369.0
MMD2_k127_741159_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000000000000000000000000002669 197.0
MMD2_k127_741159_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000002175 172.0
MMD2_k127_741159_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000051 49.0
MMD2_k127_814503_0 Transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1351.0
MMD2_k127_814503_1 Outer membrane efflux protein K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 425.0
MMD2_k127_814503_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K18145 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 355.0
MMD2_k127_814503_3 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000000000000000000005635 182.0
MMD2_k127_814503_4 - - - - 0.00001158 48.0
MMD2_k127_837452_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009301 407.0
MMD2_k127_837452_1 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 303.0
MMD2_k127_837452_2 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000002198 240.0
MMD2_k127_837452_3 - - - - 0.000000000001428 70.0
MMD2_k127_837452_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00002471 48.0
MMD2_k127_846112_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 6.322e-204 664.0
MMD2_k127_846112_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 375.0
MMD2_k127_846112_2 Short-chain dehydrogenase reductase sdr - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 294.0
MMD2_k127_846112_3 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002991 233.0
MMD2_k127_846112_4 addiction module antidote protein - - - 0.0000000000000000000000000000000000000000000198 162.0
MMD2_k127_846112_5 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000000004032 87.0
MMD2_k127_846112_7 - - - - 0.00001349 55.0
MMD2_k127_855889_0 type II secretion system protein E K02454 - - 1.932e-207 661.0
MMD2_k127_855889_1 general secretion pathway protein K02453 - - 1.353e-198 644.0
MMD2_k127_855889_2 general secretion pathway protein K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
MMD2_k127_855889_3 Type II secretion system (T2SS), protein K K02460 - - 0.000000000000000000000000000000000000000000000000000000000007784 218.0
MMD2_k127_855889_4 General Secretory Pathway K02463 - - 0.000000000000000000000000000000000000000004657 165.0
MMD2_k127_855889_5 - - - - 0.000000000000000000000000000000000000002306 146.0
MMD2_k127_855889_6 General secretion pathway protein I K02458 - - 0.000000000000000000000000001915 119.0
MMD2_k127_855889_7 GspL periplasmic domain K02461 - - 0.00000000000000000000000001596 125.0
MMD2_k127_855889_8 General secretion pathway K02462 - - 0.0000000008283 70.0
MMD2_k127_871319_0 carbamoyl transferase, NodU family K00612 - - 3.348e-221 695.0
MMD2_k127_871319_1 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006465 426.0
MMD2_k127_871319_2 FecR protein - - - 0.000000003249 68.0
MMD2_k127_871319_3 - - - - 0.00000005374 61.0
MMD2_k127_87300_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1264.0
MMD2_k127_87300_1 4Fe-4S dicluster domain - - - 0.0 1108.0
MMD2_k127_87300_2 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 1.232e-315 985.0
MMD2_k127_87300_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005903 509.0
MMD2_k127_87300_4 Type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 491.0
MMD2_k127_87300_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 316.0
MMD2_k127_889331_0 carboxylase K01969 - 6.4.1.4 1.771e-274 855.0
MMD2_k127_889331_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 509.0
MMD2_k127_889331_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000919 301.0
MMD2_k127_889331_3 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000004014 237.0
MMD2_k127_889331_4 COG1024 Enoyl-CoA hydratase carnithine racemase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000009989 181.0
MMD2_k127_92883_0 Found in ATP-dependent protease La (LON) K01338 - 3.4.21.53 5.815e-299 938.0
MMD2_k127_92883_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 9.501e-214 670.0
MMD2_k127_92883_10 ABC transporter permease K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 295.0
MMD2_k127_92883_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 314.0
MMD2_k127_92883_12 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001631 299.0
MMD2_k127_92883_13 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001354 270.0
MMD2_k127_92883_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002556 263.0
MMD2_k127_92883_15 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000001609 209.0
MMD2_k127_92883_16 NUDIX domain - - - 0.0000000000000000000000000000000000000000000000216 176.0
MMD2_k127_92883_17 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000000000001025 149.0
MMD2_k127_92883_18 stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000004993 153.0
MMD2_k127_92883_19 Cupredoxin-like domain - - - 0.000000000000000000000000000000000006963 139.0
MMD2_k127_92883_2 Phosphoesterase family - - - 6.43e-205 648.0
MMD2_k127_92883_20 Type II secretory pathway component PulJ K02459 - - 0.00000000000000000000004419 106.0
MMD2_k127_92883_21 general secretion pathway protein K02452 - - 0.0000000000002391 82.0
MMD2_k127_92883_22 General secretion pathway protein h K02457 - - 0.000000000004748 73.0
MMD2_k127_92883_23 Trypsin K04691,K04772 - - 0.0004736 42.0
MMD2_k127_92883_3 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 602.0
MMD2_k127_92883_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 470.0
MMD2_k127_92883_5 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 377.0
MMD2_k127_92883_6 ABC transporter K02028,K10004 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 368.0
MMD2_k127_92883_7 Glutathione S-transferase K03599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 332.0
MMD2_k127_92883_8 Psort location CytoplasmicMembrane, score K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 318.0
MMD2_k127_92883_9 Binding-protein-dependent transport system inner membrane component K02029,K10002 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 312.0
MMD2_k127_930968_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005113 393.0
MMD2_k127_930968_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 395.0
MMD2_k127_930968_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008739 360.0
MMD2_k127_930968_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000000001558 194.0
MMD2_k127_930968_4 transcriptional - - - 0.00000000000000000000000000000000000000000000405 168.0
MMD2_k127_930968_5 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000001383 149.0
MMD2_k127_930968_6 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000001249 147.0
MMD2_k127_930968_7 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000006293 126.0
MMD2_k127_930968_8 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000005019 120.0
MMD2_k127_930968_9 peptidase, M23 - - - 0.0000000001049 74.0
MMD2_k127_935144_0 Major Facilitator Superfamily - - - 4.869e-259 807.0
MMD2_k127_935144_1 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006759 490.0
MMD2_k127_935144_2 Amidohydrolase K22213 - 4.1.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 332.0
MMD2_k127_935144_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003683 274.0
MMD2_k127_935144_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000000000000000000004158 175.0
MMD2_k127_940866_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 2.934e-320 1002.0
MMD2_k127_940866_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 459.0
MMD2_k127_940866_2 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 441.0
MMD2_k127_940866_3 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 402.0
MMD2_k127_940866_4 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008339 353.0
MMD2_k127_940866_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008369 348.0
MMD2_k127_940866_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000002491 262.0
MMD2_k127_940866_7 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000001244 222.0
MMD2_k127_940866_8 DsrE/DsrF-like family - - - 0.0000000000000000000000000000000000000000000000000000002704 196.0
MMD2_k127_96152_0 pfam abc - - - 9.242e-252 786.0
MMD2_k127_96152_1 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 593.0
MMD2_k127_96152_2 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 380.0
MMD2_k127_96152_3 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 369.0
MMD2_k127_96152_4 Chromate resistance - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001209 287.0
MMD2_k127_998490_0 chemotaxis sensory transducer K03406,K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 574.0
MMD2_k127_998490_1 Type IV pili methyl-accepting chemotaxis transducer N-term K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 305.0
MMD2_k127_998490_2 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000002477 227.0
MMD2_k127_998490_3 response regulator K07684 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0090352,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903314,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000006844 215.0
MMD2_k127_998538_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 464.0
MMD2_k127_998538_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 368.0
MMD2_k127_998538_2 methyl-accepting chemotaxis protein K03406,K05874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008755 297.0
MMD2_k127_998538_3 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000003591 239.0
MMD2_k127_998538_4 Chemotaxis signal transduction protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000007227 206.0
MMD2_k127_998538_5 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000001878 197.0