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Overview

ID MAG02358
Name MMD2_bin.19
Sample SMP0059
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA9159
Genus
Species
Assembly information
Completeness (%) 90.2
Contamination (%) 6.48
GC content (%) 54.0
N50 (bp) 5,700
Genome size (bp) 2,319,387

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2389

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1011877_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 7.373e-300 939.0
MMD2_k127_1011877_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 337.0
MMD2_k127_1011877_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 298.0
MMD2_k127_1011877_3 AsmA-like C-terminal region K07289 - - 0.000000000000002806 89.0
MMD2_k127_1011877_4 Sigma-54 interaction domain - - - 0.0000002464 62.0
MMD2_k127_1011877_5 - - - - 0.00001172 55.0
MMD2_k127_1011877_6 protein involved in outer membrane biogenesis K07289 - - 0.00005452 56.0
MMD2_k127_101358_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 524.0
MMD2_k127_1035336_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 417.0
MMD2_k127_1035336_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
MMD2_k127_1035336_2 response regulator K02485 - - 0.0000000000000000000004096 100.0
MMD2_k127_1035336_3 Transcriptional regulator, asnc family K03718 - - 0.0007322 46.0
MMD2_k127_1058504_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 537.0
MMD2_k127_1058504_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004755 286.0
MMD2_k127_1058504_2 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000007204 189.0
MMD2_k127_1088023_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18903 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 542.0
MMD2_k127_1088023_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 463.0
MMD2_k127_1088023_2 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 335.0
MMD2_k127_1088023_3 metallopeptidase activity K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003274 248.0
MMD2_k127_1093952_0 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 379.0
MMD2_k127_1093952_1 Aminoacyl-tRNA editing domain K03976 - - 0.0000000000000000000002882 99.0
MMD2_k127_1118570_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1677.0
MMD2_k127_1118570_1 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1621.0
MMD2_k127_1118570_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 349.0
MMD2_k127_1118570_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004562 272.0
MMD2_k127_1118570_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000008239 224.0
MMD2_k127_1118570_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000005967 194.0
MMD2_k127_1118570_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000001302 151.0
MMD2_k127_1130350_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.319e-196 619.0
MMD2_k127_1130350_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 603.0
MMD2_k127_1130350_2 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003613 255.0
MMD2_k127_1130350_3 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000001066 230.0
MMD2_k127_1130350_4 Lysin motif - - - 0.000000000000000000000000000000000003056 150.0
MMD2_k127_1130350_5 Putative zinc-finger - - - 0.000000000002419 68.0
MMD2_k127_1136195_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 466.0
MMD2_k127_1136195_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006169 382.0
MMD2_k127_1136195_2 Cytochrome c554 and c-prime - - - 0.000000000000000000008002 93.0
MMD2_k127_1148086_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.758e-282 874.0
MMD2_k127_1148086_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 5.776e-194 611.0
MMD2_k127_1148086_2 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 296.0
MMD2_k127_1148086_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 251.0
MMD2_k127_1148086_4 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000004192 197.0
MMD2_k127_1148086_5 diguanylate cyclase - - - 0.0000000000000000000000000000000000000003096 157.0
MMD2_k127_1148086_6 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000006262 66.0
MMD2_k127_1154034_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 450.0
MMD2_k127_1154034_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 432.0
MMD2_k127_1154034_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002197 284.0
MMD2_k127_1154034_3 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001418 246.0
MMD2_k127_1154034_4 methylamine metabolic process K15977 - - 0.0000000000000000000000000000000000000000000000000000000000006536 211.0
MMD2_k127_1154034_5 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.0000000000000000000000000000000000000000000000000001128 195.0
MMD2_k127_1154034_6 ATPase activity K02013,K02028,K05776 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.21,3.6.3.34 0.0000000000000000000000000000000000000000001391 162.0
MMD2_k127_1154034_7 membrane - - - 0.00000000000000000000000000000000000003099 147.0
MMD2_k127_1154034_8 Pyrophosphatase - - - 0.00000000000000000000000000000003058 136.0
MMD2_k127_1154034_9 - - - - 0.000000000000000000000000000002942 126.0
MMD2_k127_1178794_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 475.0
MMD2_k127_1178794_1 COG1194 A G-specific DNA glycosylase K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 314.0
MMD2_k127_1178794_2 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
MMD2_k127_1178794_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000002111 219.0
MMD2_k127_118206_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 595.0
MMD2_k127_118206_1 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 355.0
MMD2_k127_118206_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 343.0
MMD2_k127_118206_3 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003984 255.0
MMD2_k127_118206_4 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000002957 220.0
MMD2_k127_118206_5 - - - - 0.00000000000000000000000000000000000000000000000000000000003014 211.0
MMD2_k127_118206_6 PFAM ATP-binding region, ATPase domain protein K02482 - 2.7.13.3 0.0000000003086 66.0
MMD2_k127_1189538_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 484.0
MMD2_k127_1189538_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 312.0
MMD2_k127_1189538_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000003775 223.0
MMD2_k127_1189538_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000417 224.0
MMD2_k127_1189538_4 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.00000000000000000000001102 104.0
MMD2_k127_1189538_5 PSP1 domain protein - - - 0.000000002251 59.0
MMD2_k127_1211637_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1057.0
MMD2_k127_1211637_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 396.0
MMD2_k127_1211637_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000002537 130.0
MMD2_k127_1213999_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 499.0
MMD2_k127_1213999_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 379.0
MMD2_k127_1213999_2 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000005014 219.0
MMD2_k127_1213999_3 HupE / UreJ protein K03192 - - 0.0000000000000000000000000000000000000000000000000000008031 202.0
MMD2_k127_1213999_4 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000003401 113.0
MMD2_k127_1213999_5 Cytochrome c K02305 - - 0.000000007248 62.0
MMD2_k127_1214378_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 602.0
MMD2_k127_1214378_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000003723 91.0
MMD2_k127_1239186_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 608.0
MMD2_k127_1239186_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 531.0
MMD2_k127_1239186_10 - - - - 0.0000008285 58.0
MMD2_k127_1239186_11 - - - - 0.00001483 47.0
MMD2_k127_1239186_12 protein histidine kinase activity K02491,K13533,K14986 - 2.7.13.3 0.00004439 54.0
MMD2_k127_1239186_2 PFAM PfkB K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005235 396.0
MMD2_k127_1239186_3 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
MMD2_k127_1239186_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007468 285.0
MMD2_k127_1239186_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000008299 244.0
MMD2_k127_1239186_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000001043 225.0
MMD2_k127_1239186_7 Protein tyrosine serine phosphatase - - - 0.000000000000000000000000000005699 132.0
MMD2_k127_1239186_8 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000001327 118.0
MMD2_k127_1239186_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000006385 96.0
MMD2_k127_1247842_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 514.0
MMD2_k127_1247842_1 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000177 463.0
MMD2_k127_1247842_2 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007965 356.0
MMD2_k127_1247842_3 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009007 334.0
MMD2_k127_1247842_4 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 312.0
MMD2_k127_1247842_5 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000127 167.0
MMD2_k127_1247842_6 NmrA-like family - - - 0.0000000000000000000000000000000001188 136.0
MMD2_k127_1247842_7 iron-sulfur cluster assembly - - - 0.0000000000000000000000002987 106.0
MMD2_k127_1247842_8 Cobalt transport protein K16785 - - 0.000000000000000001536 94.0
MMD2_k127_1259743_0 Sugar (and other) transporter K03446 - - 1.021e-241 755.0
MMD2_k127_1259743_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 482.0
MMD2_k127_1259743_10 - - - - 0.0000006516 51.0
MMD2_k127_1259743_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 433.0
MMD2_k127_1259743_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 396.0
MMD2_k127_1259743_4 HlyD membrane-fusion protein of T1SS K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 398.0
MMD2_k127_1259743_5 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002713 254.0
MMD2_k127_1259743_6 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000282 249.0
MMD2_k127_1259743_7 MarC family integral membrane protein - - - 0.0000000000000000000000000000000000000000002199 165.0
MMD2_k127_1259743_8 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0000000000000000009793 89.0
MMD2_k127_1259743_9 - - - - 0.00000000000000009558 87.0
MMD2_k127_1305700_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 8.901e-207 677.0
MMD2_k127_1305700_1 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 321.0
MMD2_k127_1305700_2 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000005401 190.0
MMD2_k127_1305700_3 protein methyltransferase activity K00595 - 2.1.1.132 0.0000000000000000000000000000000000000004419 157.0
MMD2_k127_1305700_4 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000226 153.0
MMD2_k127_1305700_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000001654 75.0
MMD2_k127_1305700_6 TonB dependent receptor K02014,K16089 - - 0.0002294 44.0
MMD2_k127_1335785_0 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 429.0
MMD2_k127_1335785_1 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000001242 227.0
MMD2_k127_1335785_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000003494 190.0
MMD2_k127_1340022_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 486.0
MMD2_k127_1340022_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 478.0
MMD2_k127_1340022_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 385.0
MMD2_k127_1340022_3 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 291.0
MMD2_k127_1340022_4 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007059 242.0
MMD2_k127_1340022_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000852 233.0
MMD2_k127_1340022_6 cyclic nucleotide binding - - - 0.00000000000000000000001904 115.0
MMD2_k127_1340022_7 cheY-homologous receiver domain - - - 0.000008512 58.0
MMD2_k127_1344671_0 NUDIX domain K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000008691 189.0
MMD2_k127_1344671_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000002279 169.0
MMD2_k127_1344671_2 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000004246 151.0
MMD2_k127_1344671_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000001391 94.0
MMD2_k127_1344671_4 ribosome binding - - - 0.0000000000000000007337 87.0
MMD2_k127_139405_0 PFAM Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 520.0
MMD2_k127_139405_1 belongs to the bacterial solute-binding protein 3 family K02030,K09969,K10001 - - 0.000000000000000000000000000000000000000000000000002442 185.0
MMD2_k127_1395396_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1192.0
MMD2_k127_1395396_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 368.0
MMD2_k127_1395396_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000009864 222.0
MMD2_k127_1395396_3 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000003279 209.0
MMD2_k127_1395396_4 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000001364 102.0
MMD2_k127_1395396_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000008997 87.0
MMD2_k127_1402727_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 595.0
MMD2_k127_1412008_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 3.558e-289 900.0
MMD2_k127_1412008_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 527.0
MMD2_k127_1412008_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000000000000000000004043 238.0
MMD2_k127_1412008_4 - - - - 0.0000000000000002907 82.0
MMD2_k127_1414797_0 Glycosyl transferase family 21 - - - 3.074e-224 702.0
MMD2_k127_1414797_2 - - - - 0.0000000000000000006075 99.0
MMD2_k127_1414797_3 Tetratricopeptide repeat - - - 0.0000000003465 68.0
MMD2_k127_1425383_0 PFAM Type II secretion system protein E K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 552.0
MMD2_k127_1447267_0 Surface antigen K07277 - - 3.826e-260 822.0
MMD2_k127_1447267_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000218 228.0
MMD2_k127_1447267_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000428 212.0
MMD2_k127_1447267_3 PFAM outer membrane chaperone Skp (OmpH) K06142 - - 0.000000000000000000000003419 111.0
MMD2_k127_1447267_4 - - - - 0.00000000000000001131 83.0
MMD2_k127_1447267_5 translation elongation factor activity K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000004715 78.0
MMD2_k127_1447267_7 - - - - 0.00003554 49.0
MMD2_k127_1451894_0 Domain of Unknown Function (DUF748) - - - 2.406e-265 859.0
MMD2_k127_1451894_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.103e-261 821.0
MMD2_k127_1451894_2 membrane K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000214 374.0
MMD2_k127_1451894_3 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 289.0
MMD2_k127_1451894_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005894 261.0
MMD2_k127_1451894_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000000002047 229.0
MMD2_k127_1451894_6 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000001357 222.0
MMD2_k127_1451894_7 4Fe-4S dicluster domain K00196 - - 0.000000000000000000000000000000000000000000000001073 179.0
MMD2_k127_1476440_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 479.0
MMD2_k127_1476440_1 ligase activity K01469 - 3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000137 248.0
MMD2_k127_1476440_2 methionine synthase K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000001018 209.0
MMD2_k127_1476440_3 Succinate dehydrogenase fumarate reductase flavoprotein K00394 - 1.8.99.2 0.0000001626 53.0
MMD2_k127_1504169_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 6.168e-310 963.0
MMD2_k127_1504169_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.752e-204 661.0
MMD2_k127_1504169_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 601.0
MMD2_k127_1512835_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.35e-253 808.0
MMD2_k127_1512835_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 576.0
MMD2_k127_1512835_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 473.0
MMD2_k127_1512835_3 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006781 261.0
MMD2_k127_1512835_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000004724 170.0
MMD2_k127_1512835_6 - - - - 0.00000000000000000001072 106.0
MMD2_k127_1512835_7 cell cycle K05589,K12065,K13052 - - 0.0000000000000000001117 92.0
MMD2_k127_1512835_8 DsrE/DsrF-like family - - - 0.000001475 55.0
MMD2_k127_1523891_0 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000968 367.0
MMD2_k127_1523891_1 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 358.0
MMD2_k127_1523891_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 313.0
MMD2_k127_1527346_0 Peptidase family M28 - - - 0.0 1038.0
MMD2_k127_1551016_0 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000001266 164.0
MMD2_k127_1551016_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000106 146.0
MMD2_k127_1551016_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.0000000000000001154 86.0
MMD2_k127_1561589_0 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002932 452.0
MMD2_k127_1561589_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005691 254.0
MMD2_k127_1561589_2 Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000000000000000116 165.0
MMD2_k127_1561589_3 PFAM Phosphoribosyl-ATP pyrophosphohydrolase K01523 GO:0000105,GO:0003674,GO:0003824,GO:0004636,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.6.1.31 0.00000000000000000002389 92.0
MMD2_k127_157418_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 1.407e-226 715.0
MMD2_k127_157418_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 359.0
MMD2_k127_157418_2 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000001504 243.0
MMD2_k127_157418_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000003368 181.0
MMD2_k127_1575182_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 302.0
MMD2_k127_1575182_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009433 302.0
MMD2_k127_1575182_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 299.0
MMD2_k127_1575182_3 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 286.0
MMD2_k127_1575182_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006624 274.0
MMD2_k127_1575182_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003046 257.0
MMD2_k127_1575182_6 PFAM Preprotein translocase SecG subunit K03075 - - 0.0000000000000002661 83.0
MMD2_k127_1575182_7 His Kinase A (phosphoacceptor) domain - - - 0.00000009861 61.0
MMD2_k127_16088_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007242 396.0
MMD2_k127_16088_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 348.0
MMD2_k127_16088_2 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000001218 239.0
MMD2_k127_16088_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000002177 239.0
MMD2_k127_16088_4 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000000003826 224.0
MMD2_k127_16088_5 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000006675 139.0
MMD2_k127_16088_6 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000001559 113.0
MMD2_k127_1610909_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 402.0
MMD2_k127_1610909_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 330.0
MMD2_k127_1610909_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000811 283.0
MMD2_k127_1610909_3 Response regulator receiver domain K03413 - - 0.00000000000000000000000000000000000000000005992 165.0
MMD2_k127_1610909_4 VanZ like family - - - 0.00000000000000000000000000000000000000004003 156.0
MMD2_k127_1610909_5 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000306 151.0
MMD2_k127_1610909_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000189 150.0
MMD2_k127_1610909_7 Methylmuconolactone methyl-isomerase - - - 0.000000000000003052 79.0
MMD2_k127_1612361_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1064.0
MMD2_k127_1612361_1 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 481.0
MMD2_k127_1612361_2 cysteine synthase K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 463.0
MMD2_k127_1612361_3 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 325.0
MMD2_k127_1612361_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004594 276.0
MMD2_k127_1612361_5 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002434 272.0
MMD2_k127_1612361_6 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000000000000000000000000006137 269.0
MMD2_k127_1612361_7 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000003538 228.0
MMD2_k127_1612361_8 HAD-hyrolase-like K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000003566 213.0
MMD2_k127_1612361_9 Domain of unknown function (DUF4124) - - - 0.0006044 48.0
MMD2_k127_1614989_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.159e-221 692.0
MMD2_k127_1614989_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 343.0
MMD2_k127_1614989_2 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000002448 256.0
MMD2_k127_1614989_3 PFAM ABC transporter related K01996 - - 0.000000001212 59.0
MMD2_k127_1615490_0 Belongs to the CarB family K01955 - 6.3.5.5 7.518e-228 721.0
MMD2_k127_1615490_1 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 462.0
MMD2_k127_1615490_2 - - - - 0.0000006275 54.0
MMD2_k127_1623295_0 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K11181 GO:0003674,GO:0003824,GO:0005575,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016002,GO:0016020,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0044237,GO:0050311,GO:0055114 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 325.0
MMD2_k127_1623295_1 Nitrite and sulphite reductase 4Fe-4S domain K11180,K11181 - 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006906 290.0
MMD2_k127_1623295_2 Methyltransferase type - - - 0.00000000000000000000000000000001129 127.0
MMD2_k127_1649792_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.499e-318 992.0
MMD2_k127_1649792_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 597.0
MMD2_k127_1649792_10 Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000001209 177.0
MMD2_k127_1649792_11 electron transfer activity K05337,K17247 - - 0.000000000000000000000000000002957 119.0
MMD2_k127_1649792_12 Cupin 2, conserved barrel domain protein - - - 0.0000000000311 68.0
MMD2_k127_1649792_2 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000319 406.0
MMD2_k127_1649792_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 302.0
MMD2_k127_1649792_4 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 301.0
MMD2_k127_1649792_5 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000005961 252.0
MMD2_k127_1649792_6 Domain of unknown function (DUF4337) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001357 246.0
MMD2_k127_1649792_7 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008202 249.0
MMD2_k127_1649792_8 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000588 236.0
MMD2_k127_1649792_9 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000739 217.0
MMD2_k127_1650385_0 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000001638 267.0
MMD2_k127_1650385_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000001197 228.0
MMD2_k127_1650385_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.0000000000000000000000000000000000000000000000000000001797 198.0
MMD2_k127_1650385_4 iron ion binding - - - 0.0000000000000000000000000000000745 134.0
MMD2_k127_1650385_5 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000001089 74.0
MMD2_k127_1656_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005889 486.0
MMD2_k127_1656_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 440.0
MMD2_k127_1656_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000002211 196.0
MMD2_k127_1656_3 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.0000004479 58.0
MMD2_k127_1659885_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 376.0
MMD2_k127_1659885_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005307 292.0
MMD2_k127_1659885_2 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000000002412 161.0
MMD2_k127_1662858_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 575.0
MMD2_k127_1662858_1 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000002335 227.0
MMD2_k127_1662858_2 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000002564 205.0
MMD2_k127_1662858_3 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000004436 149.0
MMD2_k127_1662858_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.0000000000000000000000008072 104.0
MMD2_k127_1662858_5 COG3209 Rhs family protein - - - 0.00000000000000001797 85.0
MMD2_k127_1664632_0 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006278 278.0
MMD2_k127_1664632_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002274 264.0
MMD2_k127_1664632_2 - - - - 0.0000000000000000000001419 102.0
MMD2_k127_1664632_3 Secretin and TonB N terminus short domain K02507,K02666 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 - 0.0000000000004723 74.0
MMD2_k127_1664632_4 LPP20 lipoprotein K09860 - - 0.000000000003681 76.0
MMD2_k127_1664632_5 - - - - 0.000000000009063 74.0
MMD2_k127_1664632_6 Curli production assembly/transport component CsgG - - - 0.0000000005866 63.0
MMD2_k127_1664632_8 LPP20 lipoprotein - - - 0.000004771 55.0
MMD2_k127_1664632_9 FecR protein - - - 0.00004089 55.0
MMD2_k127_1665661_0 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000000000004623 223.0
MMD2_k127_1665661_1 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000000002298 209.0
MMD2_k127_1665661_2 Type II secretion system (T2SS), protein G K02456 - - 0.0000000000000000000000000000000000000000003892 162.0
MMD2_k127_1665661_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000132 153.0
MMD2_k127_1665661_4 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000003061 126.0
MMD2_k127_1680618_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 568.0
MMD2_k127_1680618_1 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 466.0
MMD2_k127_1680618_10 Transcriptional regulators - - - 0.00000001187 58.0
MMD2_k127_1680618_11 Tetratricopeptide repeat protein - - - 0.000001111 59.0
MMD2_k127_1680618_12 sulfur relay protein TusB DsrH K07237 - - 0.0001663 48.0
MMD2_k127_1680618_13 PFAM DsrE K07235 - - 0.0002881 46.0
MMD2_k127_1680618_2 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004147 394.0
MMD2_k127_1680618_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 376.0
MMD2_k127_1680618_4 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003045 253.0
MMD2_k127_1680618_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000056 199.0
MMD2_k127_1680618_6 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000000008842 104.0
MMD2_k127_1680618_7 - - - - 0.00000000000000000000004701 103.0
MMD2_k127_1680618_8 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.000000000000000000002437 97.0
MMD2_k127_1680618_9 PFAM DsrE family protein K07235 - - 0.0000000009168 66.0
MMD2_k127_1695392_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 299.0
MMD2_k127_1695392_1 Phosphoribosyltransferase K00768 - 2.4.2.21 0.000000000000000000000000008631 111.0
MMD2_k127_1701990_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 326.0
MMD2_k127_1701990_1 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000000000007157 169.0
MMD2_k127_1701990_2 Thioredoxin-like - - - 0.000000000000000000000000000000000003818 143.0
MMD2_k127_170559_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 342.0
MMD2_k127_170559_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000000007796 172.0
MMD2_k127_170559_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000002225 139.0
MMD2_k127_1710064_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 304.0
MMD2_k127_1710064_1 Glycine-zipper domain - - - 0.0000000000000000000000000000000000000006794 154.0
MMD2_k127_1710064_2 - - - - 0.0000000000000000008304 92.0
MMD2_k127_1710064_3 Cysteine synthase K01738,K12339 - 2.5.1.47 0.0009522 42.0
MMD2_k127_1719346_0 General secretory system II, protein E domain protein K02454 - - 9.026e-200 638.0
MMD2_k127_1719346_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 351.0
MMD2_k127_1719346_10 Ammonium Transporter Family K03320 - - 0.0000000000000000002902 88.0
MMD2_k127_1719346_11 luxR family K21405 - - 0.0000000008965 64.0
MMD2_k127_1719346_12 - - - - 0.000000001473 61.0
MMD2_k127_1719346_2 Mur ligase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 343.0
MMD2_k127_1719346_3 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 329.0
MMD2_k127_1719346_4 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005679 269.0
MMD2_k127_1719346_5 cobalt ion transport K02007 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004951 258.0
MMD2_k127_1719346_6 SMART Signal transduction response regulator, receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000157 217.0
MMD2_k127_1719346_7 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000005802 195.0
MMD2_k127_1719346_8 PFAM Cobalt transport protein K02008 - - 0.000000000000000000000000000000001601 141.0
MMD2_k127_1719346_9 cobalt ion transport K02009 - - 0.0000000000000000000000000005844 116.0
MMD2_k127_1725980_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005603 455.0
MMD2_k127_1725980_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000006768 192.0
MMD2_k127_1739594_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.77e-322 1005.0
MMD2_k127_1739594_1 - - - - 0.00000000000000000000000000000000001015 137.0
MMD2_k127_1743038_0 Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 513.0
MMD2_k127_1743038_1 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 383.0
MMD2_k127_1743038_2 Phosphoesterase, PA-phosphatase related K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.00000000000000002591 88.0
MMD2_k127_1743038_3 transcription factor binding K10941 - - 0.000000000973 67.0
MMD2_k127_1754620_0 beta-fructofuranosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 332.0
MMD2_k127_1754620_1 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.0000000000000000000000000000000000001468 151.0
MMD2_k127_1809180_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 492.0
MMD2_k127_1809180_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 316.0
MMD2_k127_1811508_0 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006522 280.0
MMD2_k127_1811508_1 Transcriptional regulator - - - 0.0000000000000000542 81.0
MMD2_k127_1811508_2 Belongs to the UPF0235 family K09131 - - 0.0000000002397 63.0
MMD2_k127_1811673_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 331.0
MMD2_k127_1811673_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000002395 223.0
MMD2_k127_1811673_2 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.0000000000000000000000000000000000000000008328 181.0
MMD2_k127_1811673_3 PFAM CheW domain protein K03408 - - 0.0000000000000000000007301 103.0
MMD2_k127_1831443_0 Extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 564.0
MMD2_k127_1831443_1 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 456.0
MMD2_k127_1831443_2 Bacterial protein of unknown function (DUF882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 421.0
MMD2_k127_1831443_3 Binding-protein-dependent transport system inner membrane component K02026 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 352.0
MMD2_k127_1831443_4 ABC transporter permease K02025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 348.0
MMD2_k127_1831443_5 metalloendopeptidase activity K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000187 261.0
MMD2_k127_1831443_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000002772 187.0
MMD2_k127_1841341_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 4.388e-315 994.0
MMD2_k127_1841341_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 347.0
MMD2_k127_1861376_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 329.0
MMD2_k127_1861376_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005124 275.0
MMD2_k127_1861376_2 CHASE K02488,K21009 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000003347 220.0
MMD2_k127_1861376_3 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.000000000000000000000000000000000000000000000000002305 184.0
MMD2_k127_1877293_0 Heavy metal translocating P-type atpase K01533,K17686 - 3.6.3.4,3.6.3.54 3.595e-221 708.0
MMD2_k127_1877293_1 Biogenesis protein K09792 - - 0.00000000000000000000000000000006598 129.0
MMD2_k127_1877578_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 363.0
MMD2_k127_1877578_1 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 338.0
MMD2_k127_1894469_0 COG0058 Glucan phosphorylase - - - 1.556e-264 825.0
MMD2_k127_1894469_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 3.029e-221 697.0
MMD2_k127_1894469_10 MgtC family K07507 - - 0.000000000000000000000000000000000000002457 156.0
MMD2_k127_1894469_11 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.000000000000000000000000000000000003378 143.0
MMD2_k127_1894469_2 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 550.0
MMD2_k127_1894469_3 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 494.0
MMD2_k127_1894469_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 495.0
MMD2_k127_1894469_5 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 469.0
MMD2_k127_1894469_6 TIGRFAM Pyrimidine-nucleoside phosphorylase K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 456.0
MMD2_k127_1894469_7 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 338.0
MMD2_k127_1894469_8 Protein of unknown function (DUF1499) - - - 0.0000000000000000000000000000000000000000000000000000000000000003059 232.0
MMD2_k127_1894469_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000004228 216.0
MMD2_k127_1902954_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 443.0
MMD2_k127_1920546_0 NOG31153 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002997 264.0
MMD2_k127_1920546_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000003099 223.0
MMD2_k127_1920546_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000009499 111.0
MMD2_k127_1920546_3 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000004907 84.0
MMD2_k127_1920546_4 Redoxin - - - 0.0000000000001918 73.0
MMD2_k127_1920546_5 DNA-binding transcription factor activity K03892 - - 0.0000000000004569 73.0
MMD2_k127_1920546_6 Cupin 2, conserved barrel domain protein - - - 0.000000001637 60.0
MMD2_k127_1920546_7 - - - - 0.000001907 53.0
MMD2_k127_1922838_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002462 275.0
MMD2_k127_1922838_1 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000000000000000000000000000000000000000000000004238 182.0
MMD2_k127_1922838_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000001487 59.0
MMD2_k127_1933039_0 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 5.477e-203 638.0
MMD2_k127_1933039_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 448.0
MMD2_k127_1933039_2 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000001216 134.0
MMD2_k127_1933039_3 Hydrolyzes mannosyl-3-phosphoglycerate (MPG) to form the osmolyte mannosylglycerate (MG) K07026 - 3.1.3.70 0.000000000000000000000000011 111.0
MMD2_k127_1936044_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005465 546.0
MMD2_k127_1936044_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 488.0
MMD2_k127_1936044_10 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000005943 71.0
MMD2_k127_1936044_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 374.0
MMD2_k127_1936044_3 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008332 354.0
MMD2_k127_1936044_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 342.0
MMD2_k127_1936044_5 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001695 282.0
MMD2_k127_1936044_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000006525 239.0
MMD2_k127_1936044_7 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000007357 185.0
MMD2_k127_1936044_8 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.00000000000000000000000000000003325 136.0
MMD2_k127_1936044_9 - - - - 0.00000000000001537 78.0
MMD2_k127_1936718_0 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 350.0
MMD2_k127_1936718_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000000000004952 208.0
MMD2_k127_1936718_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000001158 205.0
MMD2_k127_1936718_3 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000001497 143.0
MMD2_k127_1945772_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 427.0
MMD2_k127_1945772_1 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 335.0
MMD2_k127_1945772_2 response regulator, receiver K03413 - - 0.0000000000000000000000002606 108.0
MMD2_k127_1945772_3 Protein of unknown function (DUF1189) - - - 0.00000000000000000004791 100.0
MMD2_k127_1952340_0 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 490.0
MMD2_k127_1952340_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000003456 118.0
MMD2_k127_1952340_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000003546 73.0
MMD2_k127_1952340_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01011 - 2.8.1.1,2.8.1.2 0.00002314 47.0
MMD2_k127_1956784_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 568.0
MMD2_k127_1956784_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 430.0
MMD2_k127_1956784_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000003096 210.0
MMD2_k127_1956784_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000008392 201.0
MMD2_k127_1956784_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000006619 112.0
MMD2_k127_1956784_5 Cyclic nucleotide-binding protein - - - 0.0000000000001654 76.0
MMD2_k127_1962197_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 577.0
MMD2_k127_1962197_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 493.0
MMD2_k127_1962197_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 422.0
MMD2_k127_1962197_3 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 407.0
MMD2_k127_1962197_4 pfam abc K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 372.0
MMD2_k127_1962197_5 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004734 274.0
MMD2_k127_1968318_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1440.0
MMD2_k127_1968318_1 cell redox homeostasis - - - 1.279e-223 702.0
MMD2_k127_1968318_10 transcriptional K03892 - - 0.000000000004661 78.0
MMD2_k127_1968318_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 474.0
MMD2_k127_1968318_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 387.0
MMD2_k127_1968318_4 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 293.0
MMD2_k127_1968318_5 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 294.0
MMD2_k127_1968318_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005184 287.0
MMD2_k127_1968318_7 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008913 283.0
MMD2_k127_1968318_8 protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000001803 196.0
MMD2_k127_1968318_9 Protein of unknown function (DUF3641) - - - 0.0000000000000427 74.0
MMD2_k127_1984390_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000001184 255.0
MMD2_k127_1984390_1 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000004441 119.0
MMD2_k127_1984390_2 phosphorelay signal transduction system - - - 0.00000002786 55.0
MMD2_k127_1989285_0 Heat shock 70 kDa protein K04043 - - 0.0 1017.0
MMD2_k127_1989285_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000002446 87.0
MMD2_k127_1993654_0 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 390.0
MMD2_k127_1993654_1 Domain of unknown function (DUF3463) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000214 248.0
MMD2_k127_1993654_2 PFAM Prenyltransferase squalene oxidase K01852,K06045 - 4.2.1.129,5.4.99.17,5.4.99.7 0.00000000000000000000000000000000000000000000000000000000000000007866 224.0
MMD2_k127_1993654_3 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000001587 159.0
MMD2_k127_1993654_4 Protein of unknown function DUF116 - - - 0.000000000000000000000000000000000000001507 157.0
MMD2_k127_1993654_5 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000001118 149.0
MMD2_k127_1995368_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.857e-248 774.0
MMD2_k127_1995368_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 537.0
MMD2_k127_1995368_2 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 527.0
MMD2_k127_1995368_3 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000002764 173.0
MMD2_k127_2026928_0 Surface antigen K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 484.0
MMD2_k127_2026928_1 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000000000000000000004645 139.0
MMD2_k127_2035387_0 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004162 281.0
MMD2_k127_2035387_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004487 258.0
MMD2_k127_2035387_2 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000001369 176.0
MMD2_k127_2035387_3 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000001249 140.0
MMD2_k127_2035387_4 NMT1-like family - - - 0.0000000000000000000000009078 107.0
MMD2_k127_2035387_5 - - - - 0.0000000000000000000004486 99.0
MMD2_k127_2035387_6 Nitrate reductase gamma subunit - - - 0.000000000000000000001711 103.0
MMD2_k127_2050308_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 310.0
MMD2_k127_2050308_1 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 288.0
MMD2_k127_2050308_2 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000001117 241.0
MMD2_k127_2050308_3 snoRNA binding - - - 0.000000000000001137 81.0
MMD2_k127_2064176_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001444 264.0
MMD2_k127_2064176_1 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000003769 235.0
MMD2_k127_2064176_2 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000001376 120.0
MMD2_k127_2067603_0 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 491.0
MMD2_k127_2067603_1 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000009273 180.0
MMD2_k127_2067603_2 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000000009221 162.0
MMD2_k127_2067603_3 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.00000000000000000000000000001617 121.0
MMD2_k127_2068333_1 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 421.0
MMD2_k127_2068333_2 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000028 392.0
MMD2_k127_2068333_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000006641 200.0
MMD2_k127_2068333_4 cyclic nucleotide binding K07058,K14266 - 1.14.19.9 0.00000000000000000000002067 110.0
MMD2_k127_2068333_6 Domain of unknown function (DUF3786) - - - 0.0000272 48.0
MMD2_k127_2080535_0 Poly-beta-hydroxybutyrate polymerase K03821 - - 3.084e-244 765.0
MMD2_k127_2080535_1 Histidine kinase K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002226 299.0
MMD2_k127_2080535_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001308 277.0
MMD2_k127_2080535_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001431 241.0
MMD2_k127_2080535_4 HAMP domain K02482 - 2.7.13.3 0.000000000005803 77.0
MMD2_k127_2080535_5 Protein of unknown function (DUF2892) - - - 0.0000000301 64.0
MMD2_k127_2082029_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 321.0
MMD2_k127_2082029_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002494 288.0
MMD2_k127_2082029_2 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002029 266.0
MMD2_k127_2082029_3 STAS domain K04749 - - 0.000000000000000000000001357 107.0
MMD2_k127_2082029_4 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000003001 78.0
MMD2_k127_2082029_5 denitrification pathway - - - 0.00001242 49.0
MMD2_k127_2084389_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.055e-295 915.0
MMD2_k127_2084389_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 344.0
MMD2_k127_2084389_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 314.0
MMD2_k127_2084389_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 298.0
MMD2_k127_2084389_4 - K00712 - 2.4.1.52 0.000000000000000000000000000000000000002174 159.0
MMD2_k127_2084389_5 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.00000000000000000007037 101.0
MMD2_k127_2084389_6 Sporulation and spore germination - - - 0.00000000003379 71.0
MMD2_k127_2094143_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.458e-291 902.0
MMD2_k127_2094143_1 membrane-bound metal-dependent K07038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005618 286.0
MMD2_k127_2094143_2 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002161 256.0
MMD2_k127_2094143_3 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001052 202.0
MMD2_k127_2094143_4 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000652 189.0
MMD2_k127_2094143_5 Stringent starvation protein B K09985 - - 0.0000000000000000000000000000006076 127.0
MMD2_k127_2098992_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.432e-232 726.0
MMD2_k127_2098992_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 4.582e-210 661.0
MMD2_k127_2098992_10 binds to the 23S rRNA K02922 - - 0.000000000000000000000000428 105.0
MMD2_k127_2098992_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 462.0
MMD2_k127_2098992_3 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 360.0
MMD2_k127_2098992_4 ZPR1-related zinc finger protein K06874 - - 0.0000000000000000000000000000000000000000000000000000000000000162 219.0
MMD2_k127_2098992_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000026 216.0
MMD2_k127_2098992_6 PFAM PUA domain containing protein K07575 - - 0.000000000000000000000000000000000000000000000000000000002496 203.0
MMD2_k127_2098992_7 Pfam:DUF552 K09152 - - 0.00000000000000000000000000000000000000000000000000002521 190.0
MMD2_k127_2098992_8 Thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000969 163.0
MMD2_k127_2098992_9 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.00000000000000000000000000000000000001163 144.0
MMD2_k127_2102322_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 348.0
MMD2_k127_2102322_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000001077 212.0
MMD2_k127_2102322_2 Cupin domain - - - 0.00000000000000000000000000000000000000004613 156.0
MMD2_k127_2102322_3 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000001487 139.0
MMD2_k127_2102322_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000001873 110.0
MMD2_k127_2102322_5 PBP superfamily domain K05772 - - 0.00000000000000000000000002715 111.0
MMD2_k127_2109437_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1126.0
MMD2_k127_2109437_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 624.0
MMD2_k127_2109437_2 citrate synthase K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008859 304.0
MMD2_k127_2109437_3 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000611 299.0
MMD2_k127_2109437_4 2Fe-2S -binding domain K13483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 284.0
MMD2_k127_2109437_5 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000001279 239.0
MMD2_k127_2111974_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003683 275.0
MMD2_k127_2111974_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000001718 189.0
MMD2_k127_2111974_2 protein secretion K03116 - - 0.0000000000003174 70.0
MMD2_k127_2127563_0 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 469.0
MMD2_k127_2127563_1 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 397.0
MMD2_k127_2127563_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003116 270.0
MMD2_k127_2127563_3 PFAM ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000518 232.0
MMD2_k127_2127563_4 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000004988 150.0
MMD2_k127_2150800_0 Transport of potassium into the cell K03549 - - 8.65e-249 782.0
MMD2_k127_2150800_1 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008974 576.0
MMD2_k127_2150800_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 443.0
MMD2_k127_2150800_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000002938 94.0
MMD2_k127_2150800_4 Protein of unknown function (DUF2934) - - - 0.00008185 48.0
MMD2_k127_2164535_0 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 438.0
MMD2_k127_2164535_1 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000002113 98.0
MMD2_k127_2178431_0 phosphorelay signal transduction system K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 415.0
MMD2_k127_2178431_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 390.0
MMD2_k127_2178431_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000118 219.0
MMD2_k127_2178431_3 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000000000001846 149.0
MMD2_k127_2178431_4 - - - - 0.00000000000000005435 86.0
MMD2_k127_22043_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 495.0
MMD2_k127_22043_1 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009608 449.0
MMD2_k127_22043_10 - - - - 0.0003189 45.0
MMD2_k127_22043_2 PFAM glycosyl transferase, family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 358.0
MMD2_k127_22043_4 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000002556 184.0
MMD2_k127_22043_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000001872 158.0
MMD2_k127_22043_8 sulfur carrier activity - GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0019725,GO:0033554,GO:0042592,GO:0048878,GO:0050896,GO:0051716,GO:0055082,GO:0065007,GO:0065008 - 0.00000000001074 64.0
MMD2_k127_2219889_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1312.0
MMD2_k127_2234862_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.638e-200 638.0
MMD2_k127_2234862_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 522.0
MMD2_k127_2234862_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 358.0
MMD2_k127_2234862_3 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000001125 91.0
MMD2_k127_2249527_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005134 458.0
MMD2_k127_2249527_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 417.0
MMD2_k127_2249527_10 PFAM glycosyl transferase family 2 - - - 0.000001164 53.0
MMD2_k127_2249527_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 391.0
MMD2_k127_2249527_3 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000006173 226.0
MMD2_k127_2249527_4 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000007926 205.0
MMD2_k127_2249527_5 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000006916 153.0
MMD2_k127_2249527_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000004624 134.0
MMD2_k127_2249527_7 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000005087 124.0
MMD2_k127_2249527_8 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000001442 114.0
MMD2_k127_2249527_9 Glycosyl transferase, family 2 - - - 0.000000389 53.0
MMD2_k127_227020_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.989e-198 626.0
MMD2_k127_227020_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 332.0
MMD2_k127_227020_2 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000003063 190.0
MMD2_k127_227020_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000006134 162.0
MMD2_k127_227020_4 - - - - 0.00000000000000000000000000000000000001641 157.0
MMD2_k127_227020_5 nucleotide metabolic process - - - 0.00000000000000000000000000000000001179 145.0
MMD2_k127_227020_6 helix-turn-helix- domain containing protein, AraC type - - - 0.0000000000000000000000000002289 123.0
MMD2_k127_227020_7 Mechanosensitive ion channel - - - 0.0000000000002262 81.0
MMD2_k127_2271388_0 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000002075 261.0
MMD2_k127_2271388_1 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000259 224.0
MMD2_k127_2271388_2 Domain of unknown function (DUF1858) - - - 0.00000000000000305 76.0
MMD2_k127_2271388_4 - - - - 0.0001884 47.0
MMD2_k127_2271388_5 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0004604 43.0
MMD2_k127_2287363_0 Dehydratase family K01687 - 4.2.1.9 6.373e-272 844.0
MMD2_k127_2316281_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1082.0
MMD2_k127_2338216_0 heme-copper terminal oxidase activity K02274 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 483.0
MMD2_k127_2338216_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 322.0
MMD2_k127_2338216_2 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000006618 239.0
MMD2_k127_2338216_3 kinase activity K01006,K01007,K22424 - 2.7.3.13,2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000001972 259.0
MMD2_k127_2338216_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000005853 229.0
MMD2_k127_2338216_5 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.00000000001914 68.0
MMD2_k127_2350576_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 406.0
MMD2_k127_2350576_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 368.0
MMD2_k127_2350576_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 341.0
MMD2_k127_2350576_3 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 312.0
MMD2_k127_2350576_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000001891 168.0
MMD2_k127_2350576_5 protein secretion K03116 - - 0.0000000000003683 70.0
MMD2_k127_2350866_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009533 479.0
MMD2_k127_2350866_1 Phosphoglucose isomerase K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 457.0
MMD2_k127_2350866_2 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000008499 219.0
MMD2_k127_2350866_3 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000008771 152.0
MMD2_k127_2350866_4 Glycine zipper 2TM domain - - - 0.0000000000000000000000000000000000000002076 154.0
MMD2_k127_2350866_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000001112 151.0
MMD2_k127_2350866_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00006318 45.0
MMD2_k127_2368227_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 544.0
MMD2_k127_2368227_1 HlyD family secretion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003623 496.0
MMD2_k127_2368227_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 359.0
MMD2_k127_2368227_3 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 359.0
MMD2_k127_2368227_4 COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.00000001093 59.0
MMD2_k127_2369958_0 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 7.882e-209 656.0
MMD2_k127_2369958_1 Phosphoglycerate kinase K00927 - 2.7.2.3 7.168e-195 616.0
MMD2_k127_2369958_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004171 316.0
MMD2_k127_2369958_3 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003941 260.0
MMD2_k127_2369958_4 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000003516 180.0
MMD2_k127_2369958_5 - - - - 0.000000000000000000000000000009291 130.0
MMD2_k127_2369958_6 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000002688 115.0
MMD2_k127_2369958_7 PFAM membrane protein of K08972 - - 0.000000000000000000000000143 110.0
MMD2_k127_2369958_8 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0000000000000002777 80.0
MMD2_k127_2369958_9 - - - - 0.0000000000009715 73.0
MMD2_k127_2383345_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 565.0
MMD2_k127_2383345_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 553.0
MMD2_k127_2383345_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 495.0
MMD2_k127_2383345_3 - - - - 0.000000000000001063 83.0
MMD2_k127_2383345_4 Belongs to the P-Pant transferase superfamily K00950 - 2.7.6.3 0.0004605 44.0
MMD2_k127_2385052_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 597.0
MMD2_k127_2385052_1 - - - - 0.00000000000000000000000000000000000000006712 159.0
MMD2_k127_2385052_2 PFAM thiamineS protein - - - 0.000000000000004226 78.0
MMD2_k127_2394855_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000004878 219.0
MMD2_k127_2394855_1 - - - - 0.00000000000000001509 93.0
MMD2_k127_2401039_0 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 376.0
MMD2_k127_2401039_1 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000006738 209.0
MMD2_k127_2415948_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004044 353.0
MMD2_k127_2415948_1 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008775 352.0
MMD2_k127_2415948_10 Belongs to the UPF0235 family K09131 - - 0.000000000000004123 78.0
MMD2_k127_2415948_2 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000003229 276.0
MMD2_k127_2415948_3 phosphatidate phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000002758 246.0
MMD2_k127_2415948_4 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000009948 224.0
MMD2_k127_2415948_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000002964 210.0
MMD2_k127_2415948_6 response regulator K07668,K07775 - - 0.000000000000000000000000000000000000000000000000000000345 202.0
MMD2_k127_2415948_7 TPR repeat - - - 0.00000000000000000000000000000000000000000000000002176 190.0
MMD2_k127_2415948_8 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000001907 164.0
MMD2_k127_2415948_9 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000000000000000000000000001076 138.0
MMD2_k127_2432548_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 519.0
MMD2_k127_2432548_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000001164 169.0
MMD2_k127_2435483_0 FAD binding domain K00394 - 1.8.99.2 0.0 1028.0
MMD2_k127_2435483_1 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 1.029e-207 651.0
MMD2_k127_2435483_2 FAD dependent oxidoreductase K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 535.0
MMD2_k127_2435483_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 359.0
MMD2_k127_2435483_4 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000006936 250.0
MMD2_k127_2435483_5 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.00000000002306 65.0
MMD2_k127_2441451_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1287.0
MMD2_k127_2441451_1 SMART Signal transduction response regulator, receiver domain - - - 0.0000000000000000000000000000000000000000000000000005342 195.0
MMD2_k127_2441451_2 Protein of unknown function (DUF1460) - - - 0.000002702 58.0
MMD2_k127_2450848_0 OsmC-like protein K04063 - - 0.000000000000000000000000000000000000000000000000003351 185.0
MMD2_k127_2450848_1 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.000000000000000000001402 105.0
MMD2_k127_2450848_2 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.00000000000000000002365 94.0
MMD2_k127_2450848_3 Type IV pilus biogenesis stability protein PilW - - - 0.00000003183 56.0
MMD2_k127_2455687_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1195.0
MMD2_k127_2455687_1 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000002135 266.0
MMD2_k127_2455687_2 energy transducer activity K03832 - - 0.00000000000000000000000000000000000000003581 163.0
MMD2_k127_2464837_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.336e-216 677.0
MMD2_k127_2464837_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000001108 86.0
MMD2_k127_2464837_3 Protein of unknown function (DUF1059) - - - 0.00000002203 57.0
MMD2_k127_2464837_4 Tetratricopeptide repeat - - - 0.00002026 57.0
MMD2_k127_2464837_5 - - - - 0.00005332 45.0
MMD2_k127_2465321_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.439e-219 687.0
MMD2_k127_2465321_1 response regulator, receiver - - - 0.0000000000000000000000000000000002978 136.0
MMD2_k127_2465321_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0009869 44.0
MMD2_k127_2466400_0 Glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002489 278.0
MMD2_k127_2466400_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000435 264.0
MMD2_k127_2466400_2 Glycosyl transferases group 1 - - - 0.00000001597 66.0
MMD2_k127_2466400_3 O-antigen ligase K02847 - - 0.00001135 57.0
MMD2_k127_2473410_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 4.455e-218 704.0
MMD2_k127_2473410_1 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000000001032 137.0
MMD2_k127_2473410_2 Tetratricopeptide repeat - - - 0.0000000000004753 78.0
MMD2_k127_2475067_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007013 285.0
MMD2_k127_2475067_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006077 248.0
MMD2_k127_2475067_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000005324 130.0
MMD2_k127_2475067_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000003787 93.0
MMD2_k127_2484139_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 491.0
MMD2_k127_2484139_1 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 379.0
MMD2_k127_2488876_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 8.832e-294 921.0
MMD2_k127_2488876_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004607 596.0
MMD2_k127_2488876_10 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000101 145.0
MMD2_k127_2488876_11 - - - - 0.000000000000000000000000007658 112.0
MMD2_k127_2488876_12 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000006122 93.0
MMD2_k127_2488876_13 NifU-like N terminal domain K04488,K07126,K13819 - - 0.000000000001039 68.0
MMD2_k127_2488876_14 Fimbrial assembly protein (PilN) K02663 - - 0.0000000006217 67.0
MMD2_k127_2488876_15 Protein of unknown function (DUF721) - - - 0.0000004838 58.0
MMD2_k127_2488876_2 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 542.0
MMD2_k127_2488876_3 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 338.0
MMD2_k127_2488876_4 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 326.0
MMD2_k127_2488876_5 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 329.0
MMD2_k127_2488876_6 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001213 276.0
MMD2_k127_2488876_7 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000007524 250.0
MMD2_k127_2488876_8 photosystem II stabilization K02237 - - 0.00000000000000000000000000000000000000000000002033 182.0
MMD2_k127_2488876_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000004873 149.0
MMD2_k127_249179_0 AIR synthase related protein, N-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 406.0
MMD2_k127_249179_1 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 297.0
MMD2_k127_249179_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000003525 129.0
MMD2_k127_249179_3 - - - - 0.000000000000001997 82.0
MMD2_k127_2502854_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1846.0
MMD2_k127_2502854_1 cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002006 247.0
MMD2_k127_2502854_2 nitrate nitrite transporter K02575 - - 0.00000000000000000000001147 102.0
MMD2_k127_2504313_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007362 360.0
MMD2_k127_2504313_1 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000001373 148.0
MMD2_k127_2504313_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000001648 147.0
MMD2_k127_2504457_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003881 490.0
MMD2_k127_2504457_1 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 487.0
MMD2_k127_2504457_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 344.0
MMD2_k127_2504457_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0000000000000000000000000000000000000000000000000005315 194.0
MMD2_k127_2504457_4 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000001883 155.0
MMD2_k127_2504457_5 - - - - 0.00000000000000008317 85.0
MMD2_k127_2504457_6 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000222 81.0
MMD2_k127_2504457_7 - - - - 0.000003599 53.0
MMD2_k127_2504457_8 EamA-like transporter family - - - 0.0008285 47.0
MMD2_k127_2510199_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 500.0
MMD2_k127_2510199_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009759 449.0
MMD2_k127_2510199_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 370.0
MMD2_k127_2510199_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000003533 273.0
MMD2_k127_2510199_4 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000003726 109.0
MMD2_k127_2512122_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1024.0
MMD2_k127_2512122_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 498.0
MMD2_k127_2512122_12 phosphorelay sensor kinase activity - - - 0.0000006729 62.0
MMD2_k127_2512122_2 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006878 307.0
MMD2_k127_2512122_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 314.0
MMD2_k127_2512122_4 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000008819 225.0
MMD2_k127_2512122_5 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000001008 185.0
MMD2_k127_2512122_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000003316 123.0
MMD2_k127_2512122_7 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000001083 109.0
MMD2_k127_2512122_8 PFAM GAF domain protein - - - 0.0000000000000000000007888 111.0
MMD2_k127_2512122_9 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.000000000000000000000893 97.0
MMD2_k127_2528320_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.28e-258 804.0
MMD2_k127_2528320_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000002427 139.0
MMD2_k127_2528697_0 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 501.0
MMD2_k127_2528697_1 Cytochrome C and Quinol oxidase polypeptide I K04561 - 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 357.0
MMD2_k127_2528697_2 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000003339 186.0
MMD2_k127_2528697_3 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000009523 148.0
MMD2_k127_2533284_0 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005228 276.0
MMD2_k127_2533284_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003299 262.0
MMD2_k127_2533284_2 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000157 127.0
MMD2_k127_2533284_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000001689 113.0
MMD2_k127_2538120_0 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 565.0
MMD2_k127_2538120_1 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 419.0
MMD2_k127_2538120_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 344.0
MMD2_k127_2538120_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000871 293.0
MMD2_k127_2538120_4 - - - - 0.00000000000000000000000001263 119.0
MMD2_k127_2538120_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000009983 85.0
MMD2_k127_2538120_6 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0002425 44.0
MMD2_k127_254122_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.265e-212 668.0
MMD2_k127_254122_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005255 330.0
MMD2_k127_254122_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000000000000000000000000009565 130.0
MMD2_k127_2542583_0 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 343.0
MMD2_k127_2542583_1 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000001201 197.0
MMD2_k127_2542583_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000002818 176.0
MMD2_k127_2542583_3 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000001794 113.0
MMD2_k127_2544738_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 5.134e-230 718.0
MMD2_k127_2544738_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000001034 247.0
MMD2_k127_2544738_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000004255 55.0
MMD2_k127_2547239_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 359.0
MMD2_k127_2547239_1 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 305.0
MMD2_k127_2547239_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000003871 105.0
MMD2_k127_2547239_3 helix_turn_helix, mercury resistance K13640 - - 0.000000000000000181 81.0
MMD2_k127_25575_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 5.744e-224 702.0
MMD2_k127_25575_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 7.29e-221 695.0
MMD2_k127_25575_2 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 1.222e-208 660.0
MMD2_k127_25575_3 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 456.0
MMD2_k127_25575_4 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 383.0
MMD2_k127_25575_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 333.0
MMD2_k127_25575_6 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 298.0
MMD2_k127_25575_7 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 289.0
MMD2_k127_25575_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000001718 85.0
MMD2_k127_2580982_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1849.0
MMD2_k127_2603405_0 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000764 259.0
MMD2_k127_2603405_1 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.000000000000000000000000000000000000000000000000000006418 195.0
MMD2_k127_2603405_2 Protein of unknown function (DUF2905) - - - 0.00000000000000000002347 92.0
MMD2_k127_2603405_3 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0005261 46.0
MMD2_k127_2603812_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 406.0
MMD2_k127_2603812_1 Cupin 2, conserved barrel domain protein K11477 - - 0.0000000005256 64.0
MMD2_k127_2610197_0 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004217 289.0
MMD2_k127_2610197_1 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000006487 97.0
MMD2_k127_2610197_2 PFAM Mammalian cell entry related K02067 - - 0.00000000000000123 88.0
MMD2_k127_2618132_0 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009897 460.0
MMD2_k127_2618132_1 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000001356 183.0
MMD2_k127_2618132_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000929 168.0
MMD2_k127_2618132_3 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000134 153.0
MMD2_k127_2618132_4 ribosome binding - - - 0.0000000000000000007337 87.0
MMD2_k127_2649231_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 576.0
MMD2_k127_2649231_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 541.0
MMD2_k127_2649231_2 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 285.0
MMD2_k127_2649231_3 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008324 276.0
MMD2_k127_2649231_4 Domain of unknown function DUF123 - - - 0.00000000000000000000000000000002728 130.0
MMD2_k127_2653837_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 451.0
MMD2_k127_2653837_1 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 400.0
MMD2_k127_2653837_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003615 274.0
MMD2_k127_2660549_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 4.557e-242 756.0
MMD2_k127_2660549_1 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 5.121e-230 719.0
MMD2_k127_2660549_2 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000001232 241.0
MMD2_k127_2660549_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000009813 229.0
MMD2_k127_2660549_4 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000002909 188.0
MMD2_k127_2660549_5 - - - - 0.00000000000000000000000000000000000000002173 160.0
MMD2_k127_2660549_6 - - - - 0.00000000000000000001477 92.0
MMD2_k127_2660549_7 Rubredoxin - - - 0.0000000000000000002499 89.0
MMD2_k127_2662599_0 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 435.0
MMD2_k127_2662599_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 349.0
MMD2_k127_2662599_2 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000000000000000003568 92.0
MMD2_k127_2668813_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 459.0
MMD2_k127_2668813_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006855 279.0
MMD2_k127_2668813_2 PAS domain K09155 - - 0.0000000000000000000000000000000000000000000000000000000011 203.0
MMD2_k127_2668813_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000003508 203.0
MMD2_k127_2668813_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000001265 124.0
MMD2_k127_2668813_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000001316 95.0
MMD2_k127_2668813_6 - - - - 0.000000000000002413 80.0
MMD2_k127_2675197_0 PFAM Type II secretion system protein E K02454 - - 2.252e-197 627.0
MMD2_k127_2675197_1 General secretion pathway protein F K02455,K02653 - - 0.00000002573 58.0
MMD2_k127_2675197_2 Belongs to the peptidase S8 family K13274,K20276 - - 0.0003157 46.0
MMD2_k127_2676064_0 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 409.0
MMD2_k127_2676064_1 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000002424 91.0
MMD2_k127_2676064_2 PFAM Cys Met metabolism K01739,K01761 - 2.5.1.48,4.4.1.11 0.00000000001482 66.0
MMD2_k127_2683904_0 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 323.0
MMD2_k127_2683904_1 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009827 310.0
MMD2_k127_2683904_2 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008158 254.0
MMD2_k127_2683904_3 Ion transport 2 domain protein - - - 0.0000000000000001279 86.0
MMD2_k127_2686940_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 489.0
MMD2_k127_2686940_1 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 307.0
MMD2_k127_2686940_2 cytochrome complex assembly - - - 0.000000000000000000004211 96.0
MMD2_k127_2694144_0 PD-(D/E)XK nuclease superfamily - - - 2.539e-229 745.0
MMD2_k127_2694144_1 Belongs to the helicase family. UvrD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 331.0
MMD2_k127_2715340_0 CAAX prenyl protease N-terminal, five membrane helices - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 448.0
MMD2_k127_2715340_1 Arylsulfatase - - - 0.00002748 51.0
MMD2_k127_2721025_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 4.991e-302 934.0
MMD2_k127_2721025_1 Domain of unknown function (DUF4139) - - - 1.593e-203 644.0
MMD2_k127_2721025_2 - - - - 5.485e-194 612.0
MMD2_k127_2721025_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 538.0
MMD2_k127_2721025_4 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 495.0
MMD2_k127_2721025_5 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004061 249.0
MMD2_k127_2721025_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000736 218.0
MMD2_k127_272615_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 482.0
MMD2_k127_272615_1 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 409.0
MMD2_k127_272615_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 353.0
MMD2_k127_272615_3 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000001566 126.0
MMD2_k127_272615_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000003167 92.0
MMD2_k127_2731629_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.563e-205 652.0
MMD2_k127_2731629_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004496 547.0
MMD2_k127_2731629_10 Belongs to the CinA family K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000007015 124.0
MMD2_k127_2731629_11 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000002156 107.0
MMD2_k127_2731629_12 regulation of DNA repair K03565 - - 0.000000000000003831 81.0
MMD2_k127_2731629_13 - - - - 0.000000002875 59.0
MMD2_k127_2731629_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 518.0
MMD2_k127_2731629_3 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 504.0
MMD2_k127_2731629_4 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 360.0
MMD2_k127_2731629_5 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002288 286.0
MMD2_k127_2731629_7 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000000000013 193.0
MMD2_k127_2731629_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.000000000000000000000000000000000001747 146.0
MMD2_k127_2731629_9 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000000001207 137.0
MMD2_k127_2742227_0 histidine kinase A domain protein domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 303.0
MMD2_k127_2742227_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
MMD2_k127_2745994_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 419.0
MMD2_k127_2745994_1 NMT1-like family K07080 - - 0.0000000000000000000000001181 107.0
MMD2_k127_2751511_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005427 467.0
MMD2_k127_2751511_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 306.0
MMD2_k127_2751511_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 280.0
MMD2_k127_2754310_0 Belongs to the complex I 49 kDa subunit family K00333,K14090 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000004736 262.0
MMD2_k127_2754310_1 NADH ubiquinone oxidoreductase K00331,K14088 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
MMD2_k127_2754310_2 NADH dehydrogenase K14087 - - 0.000000000000000000000000000000000000000000000000000000639 196.0
MMD2_k127_2754310_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K14089 - - 0.0000000000000000000000000000000000605 137.0
MMD2_k127_2755568_0 AsmA-like C-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008964 293.0
MMD2_k127_2755568_1 Belongs to the ompA family K03286 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000003423 119.0
MMD2_k127_2762306_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 601.0
MMD2_k127_2770678_0 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 372.0
MMD2_k127_2770678_1 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 276.0
MMD2_k127_2770678_2 COG0784 FOG CheY-like receiver K11443 - - 0.000000000000000000006699 97.0
MMD2_k127_2770678_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000002025 55.0
MMD2_k127_2771713_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 426.0
MMD2_k127_2771713_1 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000878 400.0
MMD2_k127_2771713_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 370.0
MMD2_k127_2771713_3 - - - - 0.00000000000000000000000000000000000000000000000000002446 200.0
MMD2_k127_2771713_4 aminopeptidase N - - - 0.0000000000000000000000000000000000000000005927 168.0
MMD2_k127_2771713_5 - - - - 0.0000002405 54.0
MMD2_k127_2773736_0 GTP-binding protein TypA K06207 - - 4.13e-265 833.0
MMD2_k127_2773736_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 362.0
MMD2_k127_2773736_2 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 341.0
MMD2_k127_2773736_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000003552 226.0
MMD2_k127_2773736_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000009119 204.0
MMD2_k127_2773736_5 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.000000000000000000000000000000000000000000000000000007542 192.0
MMD2_k127_2773736_6 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000000000000009191 157.0
MMD2_k127_2773736_8 ATPase histidine kinase DNA gyrase B HSP90 domain protein K07636 - 2.7.13.3 0.00000000007764 73.0
MMD2_k127_2773736_9 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713 - - 0.000004835 58.0
MMD2_k127_2780533_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 355.0
MMD2_k127_2780533_1 PFAM 4Fe-4S K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 301.0
MMD2_k127_2780533_2 Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001146 265.0
MMD2_k127_2780533_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000002081 204.0
MMD2_k127_2780533_4 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000009272 133.0
MMD2_k127_2803274_0 Thiamine biosynthesis protein (ThiI) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 298.0
MMD2_k127_2803274_1 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000001745 216.0
MMD2_k127_2803274_2 - - - - 0.0001561 44.0
MMD2_k127_2812141_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003367 379.0
MMD2_k127_2812141_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000009698 171.0
MMD2_k127_2812141_2 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000004817 145.0
MMD2_k127_2815636_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.707e-242 755.0
MMD2_k127_2815636_1 translation elongation factor activity K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000002279 78.0
MMD2_k127_2820210_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 585.0
MMD2_k127_2820210_1 Histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 323.0
MMD2_k127_2820210_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000003441 205.0
MMD2_k127_2820210_3 Recombinase zinc beta ribbon domain - - - 0.00000002159 55.0
MMD2_k127_2829462_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 396.0
MMD2_k127_2829462_1 Ftsk_gamma K03466 - - 0.0000000000000000000000000000001704 125.0
MMD2_k127_2835394_0 Thioredoxin domain K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 524.0
MMD2_k127_2835394_1 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004137 396.0
MMD2_k127_2835394_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002989 273.0
MMD2_k127_2835394_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000008106 242.0
MMD2_k127_2835394_4 histidine kinase, HAMP K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000009942 250.0
MMD2_k127_2835394_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000001087 222.0
MMD2_k127_2835394_6 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000006769 220.0
MMD2_k127_2835394_8 ABC 3 transport family K09816 - - 0.000000000001544 71.0
MMD2_k127_2854201_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001262 447.0
MMD2_k127_2854201_1 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 314.0
MMD2_k127_2854201_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004594 310.0
MMD2_k127_2854201_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000002778 216.0
MMD2_k127_2854201_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000008206 192.0
MMD2_k127_2854201_5 Uncharacterised protein family UPF0066 K11261 - 1.2.7.12 0.000000000000000000000000000000001964 130.0
MMD2_k127_2854201_6 - - - - 0.000000000000000000000000001068 113.0
MMD2_k127_2855383_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 3.746e-276 863.0
MMD2_k127_2867191_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 1.178e-194 615.0
MMD2_k127_2867191_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 449.0
MMD2_k127_2867191_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000004776 229.0
MMD2_k127_2867191_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000006061 194.0
MMD2_k127_2867191_4 PFAM RNP-1 like RNA-binding protein - - - 0.00000000000000000000005095 103.0
MMD2_k127_2867191_5 CHASE2 K01768 - 4.6.1.1 0.0000000000001022 73.0
MMD2_k127_2868699_0 Peptidase, M28 family - - - 0.0000009853 61.0
MMD2_k127_2868699_1 transmembrane transport K16052 - - 0.00006777 50.0
MMD2_k127_289934_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 340.0
MMD2_k127_289934_1 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 317.0
MMD2_k127_2975260_0 histidine kinase, HAMP K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000003055 244.0
MMD2_k127_2975260_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000006184 212.0
MMD2_k127_2975260_2 tRNA-dihydrouridine synthase - GO:0008150,GO:0010565,GO:0019216,GO:0019217,GO:0019222,GO:0031323,GO:0050789,GO:0050794,GO:0062012,GO:0065007,GO:0080090 - 0.00000001646 58.0
MMD2_k127_2992861_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006688 252.0
MMD2_k127_2992861_1 retrograde transport, endosome to Golgi K07095 - - 0.0000000000000000000000000000000000000000000000000002044 189.0
MMD2_k127_2992861_2 ATP-binding region ATPase domain protein K07683 - 2.7.13.3 0.000000000000000000002582 106.0
MMD2_k127_3021793_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 587.0
MMD2_k127_3021793_1 Trypsin K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 552.0
MMD2_k127_3021793_10 Type II secretion system (T2SS), protein M subtype b - - - 0.00000005882 61.0
MMD2_k127_3021793_11 General secretion pathway protein H K02457 - - 0.00001048 55.0
MMD2_k127_3021793_12 type IV pilus modification protein PilV K02458 - - 0.00002173 54.0
MMD2_k127_3021793_13 PFAM Fimbrial assembly family protein K02461,K02662,K02663 - - 0.0004495 53.0
MMD2_k127_3021793_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 527.0
MMD2_k127_3021793_3 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 388.0
MMD2_k127_3021793_4 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 357.0
MMD2_k127_3021793_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 295.0
MMD2_k127_3021793_6 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000001173 194.0
MMD2_k127_3021793_7 Pfam:N_methyl_2 K02459 - - 0.00000000002574 73.0
MMD2_k127_3021793_8 Fimbrial assembly protein (PilN) - - - 0.0000000005281 72.0
MMD2_k127_3021793_9 type II secretion system protein E K02454 - - 0.000000002666 59.0
MMD2_k127_3021872_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 6.024e-265 833.0
MMD2_k127_3021872_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.231e-250 784.0
MMD2_k127_3026034_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 8.786e-250 783.0
MMD2_k127_3026034_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 8.697e-234 734.0
MMD2_k127_3026034_2 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 4.18e-226 703.0
MMD2_k127_3026034_3 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 503.0
MMD2_k127_3026034_4 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000001518 172.0
MMD2_k127_3026034_5 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.00000000000000000000000000000005439 129.0
MMD2_k127_3026034_6 Aminoacyl-tRNA editing domain K03976 - - 0.000000000000000000000000000002184 121.0
MMD2_k127_3069315_0 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 492.0
MMD2_k127_3069315_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 305.0
MMD2_k127_3069315_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000003341 175.0
MMD2_k127_3071356_0 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 421.0
MMD2_k127_3071356_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009581 250.0
MMD2_k127_3071356_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000003052 162.0
MMD2_k127_3071356_3 PFAM amino acid-binding ACT domain protein - - - 0.00000000005773 70.0
MMD2_k127_3071356_4 Fungalysin metallopeptidase (M36) - - - 0.0004192 48.0
MMD2_k127_3072146_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 391.0
MMD2_k127_3072146_1 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.000000000000000000000000000000000000000000000000000000001062 208.0
MMD2_k127_3072146_2 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.0000000000000000000000000000000000000000000001337 171.0
MMD2_k127_3072146_3 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.0000000001998 61.0
MMD2_k127_3089953_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 437.0
MMD2_k127_3089953_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 403.0
MMD2_k127_3089953_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 370.0
MMD2_k127_3089953_3 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000006536 199.0
MMD2_k127_3089953_4 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000001677 190.0
MMD2_k127_3089953_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000001312 178.0
MMD2_k127_3095695_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004682 599.0
MMD2_k127_3095695_1 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003172 269.0
MMD2_k127_3112421_0 Transposase IS116/IS110/IS902 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 413.0
MMD2_k127_3112421_1 TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000922 186.0
MMD2_k127_311984_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity K03182 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 555.0
MMD2_k127_311984_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000036 166.0
MMD2_k127_311984_2 transcription factor binding - - - 0.000000000000000002143 97.0
MMD2_k127_311984_3 - - - - 0.0000000000318 67.0
MMD2_k127_3136937_0 binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 341.0
MMD2_k127_3136937_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001183 229.0
MMD2_k127_3136937_2 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000002852 209.0
MMD2_k127_3136937_3 Cysteine-rich secretory protein family - - - 0.00000000000000000000000000000000000144 144.0
MMD2_k127_3142875_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.579e-294 916.0
MMD2_k127_3142875_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 383.0
MMD2_k127_3142875_10 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000001234 197.0
MMD2_k127_3142875_11 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000249 157.0
MMD2_k127_3142875_12 - - - - 0.0000000000000000000000000000000000000005692 157.0
MMD2_k127_3142875_13 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000001087 124.0
MMD2_k127_3142875_14 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000007308 68.0
MMD2_k127_3142875_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 372.0
MMD2_k127_3142875_3 phosphoglycolate phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 335.0
MMD2_k127_3142875_4 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 320.0
MMD2_k127_3142875_5 cytochrome C peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 317.0
MMD2_k127_3142875_6 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001683 284.0
MMD2_k127_3142875_7 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000005549 258.0
MMD2_k127_3142875_8 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000001278 241.0
MMD2_k127_3142875_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000002917 222.0
MMD2_k127_3162890_0 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007449 560.0
MMD2_k127_3162890_1 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 338.0
MMD2_k127_3162890_2 heat shock protein binding K05516,K05801 - - 0.000000000000000000000000000000004121 146.0
MMD2_k127_3162890_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000001675 113.0
MMD2_k127_3180474_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007332 323.0
MMD2_k127_3180474_1 Adenylylsulphate kinase K00860 - 2.7.1.25 0.000000000000000000000000000000000000000004011 160.0
MMD2_k127_3180474_2 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000004328 85.0
MMD2_k127_3194981_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 1.158e-249 786.0
MMD2_k127_3194981_1 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 411.0
MMD2_k127_3194981_10 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000000000005017 153.0
MMD2_k127_3194981_11 OsmC-like protein - - - 0.00000000000000001574 89.0
MMD2_k127_3194981_12 response regulator receiver K02481,K07713 - - 0.00004346 52.0
MMD2_k127_3194981_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 380.0
MMD2_k127_3194981_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 327.0
MMD2_k127_3194981_4 Methylenetetrahydrofolate reductase K00297 GO:0003674,GO:0003824,GO:0004489,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 315.0
MMD2_k127_3194981_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 311.0
MMD2_k127_3194981_6 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 299.0
MMD2_k127_3194981_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
MMD2_k127_3194981_8 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000003829 174.0
MMD2_k127_3194981_9 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000000004081 160.0
MMD2_k127_3224197_0 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009409 260.0
MMD2_k127_3224197_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000002451 147.0
MMD2_k127_3224197_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000006915 71.0
MMD2_k127_3224197_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.0000000003967 63.0
MMD2_k127_3224197_4 PFAM amino acid-binding ACT domain protein - - - 0.00001639 54.0
MMD2_k127_3228596_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.342e-263 822.0
MMD2_k127_3228596_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 544.0
MMD2_k127_3228596_10 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000006934 161.0
MMD2_k127_3228596_11 Cytochrome C oxidase, cbb3-type, subunit III K08906 - - 0.0000000000000000000009449 98.0
MMD2_k127_3228596_12 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000004921 60.0
MMD2_k127_3228596_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 474.0
MMD2_k127_3228596_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 456.0
MMD2_k127_3228596_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 407.0
MMD2_k127_3228596_5 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 386.0
MMD2_k127_3228596_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 327.0
MMD2_k127_3228596_7 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 308.0
MMD2_k127_3228596_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000003639 228.0
MMD2_k127_3228596_9 ACT domain - - - 0.00000000000000000000000000000000000000000000000000000000007413 207.0
MMD2_k127_3228602_0 CoA binding domain K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 529.0
MMD2_k127_3228602_1 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 491.0
MMD2_k127_3228602_2 Transketolase, pyrimidine binding domain K00162,K00167 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 449.0
MMD2_k127_3228602_3 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 408.0
MMD2_k127_3228602_4 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000007944 223.0
MMD2_k127_3228602_5 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000000005241 204.0
MMD2_k127_3228602_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000007359 164.0
MMD2_k127_3228602_7 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000000000668 121.0
MMD2_k127_323087_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 356.0
MMD2_k127_323087_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000001651 228.0
MMD2_k127_323087_2 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000006022 210.0
MMD2_k127_323087_3 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000003705 88.0
MMD2_k127_3263951_0 Phospholipase D. Active site motifs. K06131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001006 262.0
MMD2_k127_3263951_1 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000008857 211.0
MMD2_k127_3263951_2 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000001063 165.0
MMD2_k127_3263951_3 Mo-co oxidoreductase dimerisation domain - - - 0.000000000000000000001995 94.0
MMD2_k127_3263951_4 Cytochrome c1 - - - 0.000000000000001218 80.0
MMD2_k127_3265664_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 537.0
MMD2_k127_3265664_1 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 465.0
MMD2_k127_3265664_2 protocatechuate 3,4-dioxygenase activity K03381 - 1.13.11.1 0.00000000000000000000000000000000000000000004684 163.0
MMD2_k127_3265664_3 - - - - 0.000000000000000000000002045 110.0
MMD2_k127_326790_0 DNA-3-methyladenine glycosylase activity K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 288.0
MMD2_k127_326790_1 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000005569 260.0
MMD2_k127_326790_2 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000009582 205.0
MMD2_k127_326790_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000006071 107.0
MMD2_k127_3278163_0 PFAM extracellular solute-binding protein, family 5 K02035,K13893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 503.0
MMD2_k127_3278163_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 492.0
MMD2_k127_3284737_0 Elongation factor SelB, winged helix K03833 - - 2.801e-214 683.0
MMD2_k127_3284737_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002031 263.0
MMD2_k127_3284737_2 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000002033 106.0
MMD2_k127_3284737_3 Carbon-nitrogen hydrolase K03820 - - 0.00000003408 57.0
MMD2_k127_3292480_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 2.466e-221 697.0
MMD2_k127_3292480_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 518.0
MMD2_k127_3292480_2 Belongs to the SfsA family K06206 - - 0.0000000000000000000000000000000000000000000000000000005998 201.0
MMD2_k127_3292480_3 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000001676 154.0
MMD2_k127_3292480_4 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000004144 102.0
MMD2_k127_3292480_5 - - - - 0.0000000000002065 76.0
MMD2_k127_3292480_6 Calcineurin-like phosphoesterase K07098 - - 0.0000001183 56.0
MMD2_k127_3292480_7 TIGRFAM thioredoxin K03672 - 1.8.1.8 0.00007383 51.0
MMD2_k127_331310_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 2.006e-277 867.0
MMD2_k127_331310_1 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000005736 181.0
MMD2_k127_331310_2 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000002294 162.0
MMD2_k127_3314654_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 471.0
MMD2_k127_3314654_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 288.0
MMD2_k127_3314654_2 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000000000002362 226.0
MMD2_k127_3314654_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000005674 182.0
MMD2_k127_3314654_4 YGGT family K02221 - - 0.0000000000000000000000000000000000002613 146.0
MMD2_k127_3314654_5 Conserved hypothetical protein 698 - - - 0.0000000000000000000000007031 115.0
MMD2_k127_3320065_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1514.0
MMD2_k127_3320065_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 524.0
MMD2_k127_3320065_10 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000000000000000002763 167.0
MMD2_k127_3320065_11 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000005346 155.0
MMD2_k127_3320065_12 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000799 145.0
MMD2_k127_3320065_13 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000001301 136.0
MMD2_k127_3320065_14 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000439 97.0
MMD2_k127_3320065_15 Two component signalling adaptor domain - - - 0.00000000003061 69.0
MMD2_k127_3320065_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000709 464.0
MMD2_k127_3320065_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 389.0
MMD2_k127_3320065_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 329.0
MMD2_k127_3320065_5 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 287.0
MMD2_k127_3320065_6 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002137 271.0
MMD2_k127_3320065_7 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001065 275.0
MMD2_k127_3320065_8 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001263 265.0
MMD2_k127_3320065_9 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000143 235.0
MMD2_k127_3334870_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 581.0
MMD2_k127_3334870_1 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 351.0
MMD2_k127_3334870_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000005838 212.0
MMD2_k127_3334870_3 HlyD family secretion protein - - - 0.00000000000000000000000000000000002538 136.0
MMD2_k127_334825_0 Transposase for insertion sequence element - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004019 263.0
MMD2_k127_334825_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000004096 89.0
MMD2_k127_3363255_0 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 295.0
MMD2_k127_3363255_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000001454 258.0
MMD2_k127_3363255_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000000000006074 206.0
MMD2_k127_3363255_3 Glycosyl transferase group 1 - - - 0.00000000000000000000000000000000392 136.0
MMD2_k127_3363255_4 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000000006439 103.0
MMD2_k127_3371046_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004646 407.0
MMD2_k127_3371046_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007805 331.0
MMD2_k127_3371046_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000001055 170.0
MMD2_k127_3371046_11 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000001609 159.0
MMD2_k127_3371046_12 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000002798 148.0
MMD2_k127_3371046_13 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000003932 126.0
MMD2_k127_3371046_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000007769 114.0
MMD2_k127_3371046_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001585 107.0
MMD2_k127_3371046_16 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000005909 100.0
MMD2_k127_3371046_17 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000005311 87.0
MMD2_k127_3371046_18 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001689 74.0
MMD2_k127_3371046_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002561 292.0
MMD2_k127_3371046_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003554 279.0
MMD2_k127_3371046_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000008828 231.0
MMD2_k127_3371046_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000009253 226.0
MMD2_k127_3371046_6 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000001332 228.0
MMD2_k127_3371046_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000005741 217.0
MMD2_k127_3371046_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001932 201.0
MMD2_k127_3371046_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000001171 174.0
MMD2_k127_33748_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1118.0
MMD2_k127_33748_1 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 5.686e-298 939.0
MMD2_k127_33748_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 538.0
MMD2_k127_33748_3 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 507.0
MMD2_k127_33748_4 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 355.0
MMD2_k127_33748_5 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000005949 238.0
MMD2_k127_33748_6 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.000000000000000000000000000000000000000001205 160.0
MMD2_k127_33748_7 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.000000000000000000000000000000000001162 140.0
MMD2_k127_33748_8 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000002432 131.0
MMD2_k127_33748_9 cheY-homologous receiver domain - - - 0.0000000000000000000000003637 115.0
MMD2_k127_3377304_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.496e-222 699.0
MMD2_k127_3377304_1 Belongs to the GPI family K01810 - 5.3.1.9 0.000000003487 59.0
MMD2_k127_3403377_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1098.0
MMD2_k127_3403377_1 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 391.0
MMD2_k127_3403377_2 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 355.0
MMD2_k127_3403377_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 295.0
MMD2_k127_3403377_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000112 224.0
MMD2_k127_3403377_5 Oxidoreductase NAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000000000001528 186.0
MMD2_k127_3403377_6 response regulator - - - 0.000000000000000000000000000000000001097 152.0
MMD2_k127_3406271_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.307e-256 804.0
MMD2_k127_3406271_1 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 438.0
MMD2_k127_3406271_10 helix_turn_helix, arabinose operon control protein - - - 0.0000000000000000005488 96.0
MMD2_k127_3406271_11 helix-turn-helix- domain containing protein, AraC type - - - 0.00000000000000000182 96.0
MMD2_k127_3406271_12 - - - - 0.0000000000007676 70.0
MMD2_k127_3406271_13 HD domain - - - 0.0000000027 68.0
MMD2_k127_3406271_2 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 344.0
MMD2_k127_3406271_3 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 328.0
MMD2_k127_3406271_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 314.0
MMD2_k127_3406271_5 Dimerisation domain of Zinc Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 291.0
MMD2_k127_3406271_6 Beta-lactamase enzyme family K07258 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000005909 217.0
MMD2_k127_3406271_7 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000001584 179.0
MMD2_k127_3406271_8 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000002121 142.0
MMD2_k127_3406271_9 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain K07720 - - 0.0000000000000000001856 98.0
MMD2_k127_3407265_0 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 532.0
MMD2_k127_3407265_1 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000001113 171.0
MMD2_k127_3409142_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009831 567.0
MMD2_k127_3409142_1 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 474.0
MMD2_k127_3409142_2 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000001748 124.0
MMD2_k127_3411056_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.796e-204 642.0
MMD2_k127_3411056_1 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 482.0
MMD2_k127_3411056_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 357.0
MMD2_k127_3411056_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000000000000000000000001397 207.0
MMD2_k127_3411056_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000832 192.0
MMD2_k127_3425774_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 2.837e-241 761.0
MMD2_k127_3425774_1 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006628 454.0
MMD2_k127_3425774_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000004877 169.0
MMD2_k127_3432109_0 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000001647 166.0
MMD2_k127_3432109_2 transcription activator, effector binding - - - 0.00000000000000000000002042 104.0
MMD2_k127_3432109_3 bacterial-type flagellum-dependent cell motility - - - 0.0000000003898 68.0
MMD2_k127_3435625_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.852e-239 751.0
MMD2_k127_3435625_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 466.0
MMD2_k127_3435625_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000002938 221.0
MMD2_k127_3435625_3 CHASE K02488,K21009 - 2.7.7.65 0.000000000000000000000000000000000000000000002923 180.0
MMD2_k127_3435625_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528,K02823 - 1.18.1.2,1.19.1.1 0.00001791 49.0
MMD2_k127_3438411_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 3.842e-206 649.0
MMD2_k127_3438411_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000007374 218.0
MMD2_k127_3438411_2 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000001144 188.0
MMD2_k127_3455353_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 389.0
MMD2_k127_3455353_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003265 267.0
MMD2_k127_3455353_2 Diacylglycerol kinase K00901 - 2.7.1.107 0.00000000000000000000000000000000000000000000000001879 187.0
MMD2_k127_3455353_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000388 125.0
MMD2_k127_3455353_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0006343 43.0
MMD2_k127_3522802_0 GAD domain K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000002234 185.0
MMD2_k127_3522802_1 AAA domain, putative AbiEii toxin, Type IV TA system K02006 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000001079 184.0
MMD2_k127_3522802_2 Cobalt transport protein K02008 - - 0.0000000000000000000000000001685 128.0
MMD2_k127_3525266_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 456.0
MMD2_k127_3525266_1 cytochrome c biogenesis protein - - - 0.0000000000000000000000000000000000000000003313 166.0
MMD2_k127_3525266_2 cytochrome complex assembly - - - 0.000000000000000000000001682 103.0
MMD2_k127_3525266_3 snoRNA binding - - - 0.00005305 49.0
MMD2_k127_3525503_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 411.0
MMD2_k127_3566356_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006789 434.0
MMD2_k127_3566356_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 376.0
MMD2_k127_3566356_2 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 315.0
MMD2_k127_3566356_3 TIGRFAM iron-sulfur cluster binding protein - - - 0.000000000000000000000000000000000000000000000000002224 189.0
MMD2_k127_3566356_4 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000000001614 155.0
MMD2_k127_3566356_5 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000003511 147.0
MMD2_k127_3566356_6 TIGRFAM methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.000000000000000000000000000000003357 132.0
MMD2_k127_3588524_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003636 237.0
MMD2_k127_3588524_1 - - - - 0.00000000000005634 81.0
MMD2_k127_3588524_2 - - - - 0.000000000001221 72.0
MMD2_k127_3614945_0 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 340.0
MMD2_k127_3614945_1 Putative transmembrane protein (Alph_Pro_TM) - - - 0.000000000000000000000000000000000000000000000009897 181.0
MMD2_k127_3620654_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 6.671e-222 701.0
MMD2_k127_3620654_1 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 393.0
MMD2_k127_3620654_2 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 343.0
MMD2_k127_3620654_3 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000003569 115.0
MMD2_k127_3633849_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 466.0
MMD2_k127_3633849_1 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 314.0
MMD2_k127_3633849_2 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 307.0
MMD2_k127_3633849_3 Yip1 domain - - - 0.0000000000000000000000000000000000000000000002758 178.0
MMD2_k127_3633849_4 CorA-like Mg2+ transporter protein K03284 - - 0.000000009225 57.0
MMD2_k127_3636108_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 537.0
MMD2_k127_3636108_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 381.0
MMD2_k127_3636108_2 PFAM Glycosyl transferase family 2 K12992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 302.0
MMD2_k127_3636108_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001424 272.0
MMD2_k127_3636108_5 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000001322 233.0
MMD2_k127_3636108_6 CoA-binding domain K00996 - 2.7.8.6 0.00000000000000000000000000000000000000002497 160.0
MMD2_k127_3682493_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 570.0
MMD2_k127_3682493_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000894 174.0
MMD2_k127_3696395_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 499.0
MMD2_k127_3696395_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 320.0
MMD2_k127_3696395_2 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000004422 128.0
MMD2_k127_3696587_0 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000005616 209.0
MMD2_k127_3696587_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.00000000005509 71.0
MMD2_k127_3709871_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 532.0
MMD2_k127_3709871_1 PFAM Type II secretion system protein E K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 334.0
MMD2_k127_3709871_2 Fructose-bisphosphate aldolase class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 312.0
MMD2_k127_3709871_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009359 299.0
MMD2_k127_3709871_4 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005782 267.0
MMD2_k127_3742257_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 5.054e-209 656.0
MMD2_k127_3742257_1 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 427.0
MMD2_k127_3742257_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 409.0
MMD2_k127_3742257_3 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 372.0
MMD2_k127_3742257_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 351.0
MMD2_k127_3742257_5 Vitamin K epoxide reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001319 245.0
MMD2_k127_3742257_6 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000002146 233.0
MMD2_k127_3742257_7 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000005174 219.0
MMD2_k127_3742257_8 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000454 181.0
MMD2_k127_3742257_9 - - - - 0.000000000000003122 78.0
MMD2_k127_3765241_0 PFAM PilT protein domain protein K06865 - - 1.201e-230 722.0
MMD2_k127_3765241_1 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.0000000000000000000000000000000000000000000000000000000000000000000000001731 255.0
MMD2_k127_3765241_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.00000000000000000000000000000000000000000000000002644 188.0
MMD2_k127_3765241_3 - - - - 0.000000000000000000000000000000001169 139.0
MMD2_k127_3767602_0 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 530.0
MMD2_k127_3767602_1 GHKL domain K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 471.0
MMD2_k127_3783763_0 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007946 508.0
MMD2_k127_379014_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1261.0
MMD2_k127_379014_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004754 263.0
MMD2_k127_379014_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000006634 203.0
MMD2_k127_379014_3 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000001353 191.0
MMD2_k127_379014_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000001983 131.0
MMD2_k127_379014_5 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000006601 109.0
MMD2_k127_379014_6 - - - - 0.000007411 49.0
MMD2_k127_3802610_0 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 614.0
MMD2_k127_3855693_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 518.0
MMD2_k127_3855693_1 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001724 287.0
MMD2_k127_3855693_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 257.0
MMD2_k127_3855693_3 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000001399 178.0
MMD2_k127_3855693_4 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000216 166.0
MMD2_k127_3855693_5 Roadblock/LC7 domain - - - 0.00000000000000000003596 94.0
MMD2_k127_3862835_0 Beta-ketoacyl synthase, N-terminal domain K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 352.0
MMD2_k127_3862835_1 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000003265 147.0
MMD2_k127_3862835_2 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.0002332 50.0
MMD2_k127_3872790_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009475 280.0
MMD2_k127_3872790_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000004735 141.0
MMD2_k127_3872790_2 regulator of chromosome condensation, RCC1 - - - 0.0001425 47.0
MMD2_k127_3879056_0 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 603.0
MMD2_k127_3879056_1 - - - - 0.000000000121 64.0
MMD2_k127_3879056_2 CAAX protease self-immunity K07052 - - 0.0001545 47.0
MMD2_k127_3887407_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 1.722e-248 772.0
MMD2_k127_3887407_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 551.0
MMD2_k127_3887407_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 520.0
MMD2_k127_3887407_3 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003507 387.0
MMD2_k127_3887407_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 341.0
MMD2_k127_3887407_5 Coenzyme F420-reducing hydrogenase, delta subunit K00442 - - 0.0000000000000000000000000000000000000000000000003791 179.0
MMD2_k127_3909841_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004029 247.0
MMD2_k127_3909841_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000001152 209.0
MMD2_k127_3909841_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000002401 130.0
MMD2_k127_3915676_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 580.0
MMD2_k127_3915676_1 TIGRFAM phosphodiesterase, MJ0936 family K07095 - - 0.00004165 46.0
MMD2_k127_3917716_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 358.0
MMD2_k127_3917716_1 PINc domain ribonuclease K09006 - - 0.0000000000000000000000000000000000000000000000000000000000000003847 229.0
MMD2_k127_3917716_2 epimerase dehydratase K07071 - - 0.0000000000000000000000000000002692 129.0
MMD2_k127_391948_0 Aldehyde dehydrogenase family K22187 - - 1.576e-197 627.0
MMD2_k127_391948_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 573.0
MMD2_k127_391948_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 507.0
MMD2_k127_391948_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 492.0
MMD2_k127_391948_4 (2R)-phospho-3-sulfolactate synthase (ComA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 421.0
MMD2_k127_391948_5 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 318.0
MMD2_k127_391948_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 335.0
MMD2_k127_3930364_0 Mo-molybdopterin cofactor metabolic process K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004586 265.0
MMD2_k127_3930364_1 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000000000005415 185.0
MMD2_k127_3931657_0 PFAM Glycosyl transferase, group 1 K00743 - 2.4.1.87 0.0000000000000000000000000000000000000000000000000000008883 207.0
MMD2_k127_3931657_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000009258 188.0
MMD2_k127_3944994_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.426e-271 847.0
MMD2_k127_3944994_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000006685 226.0
MMD2_k127_3944994_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.00000000000000000000000000000000000000000000000000000000002936 207.0
MMD2_k127_3944994_3 Protein of unknown function (DUF3617) - - - 0.0000000000000000000000000000000000147 139.0
MMD2_k127_3953188_0 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 435.0
MMD2_k127_3953188_1 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 323.0
MMD2_k127_3953188_2 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000004775 231.0
MMD2_k127_3953188_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000005597 229.0
MMD2_k127_3953188_4 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000007259 226.0
MMD2_k127_3953188_5 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.00000000000000000000000000001804 120.0
MMD2_k127_3959177_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 7.882e-209 656.0
MMD2_k127_3959177_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 3.393e-200 628.0
MMD2_k127_3959177_2 Predicted membrane protein (DUF2238) K08984 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008544 285.0
MMD2_k127_3959177_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005408 276.0
MMD2_k127_3959177_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000003419 235.0
MMD2_k127_3959177_5 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.00000000000000000000000000000000000000000000000000000003561 205.0
MMD2_k127_3959177_6 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000002323 187.0
MMD2_k127_3959177_7 Protein of unknown function (DUF1264) - - - 0.0000000000000008605 83.0
MMD2_k127_3959177_8 PFAM Lytic transglycosylase catalytic K08309 - - 0.0000001939 60.0
MMD2_k127_3959177_9 Trypsin - - - 0.0001764 46.0
MMD2_k127_3978870_0 Domain of unknown function (DUF3458_C) ARM repeats K01256,K08776 - 3.4.11.2 9.22e-269 836.0
MMD2_k127_3989400_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002035 274.0
MMD2_k127_3989400_1 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007121 278.0
MMD2_k127_3989400_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000002598 248.0
MMD2_k127_3989400_3 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001244 250.0
MMD2_k127_3989400_4 Plasmid stabilization system K19092 GO:0002790,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030255,GO:0032940,GO:0032991,GO:0033036,GO:0042886,GO:0043684,GO:0044097,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0097159,GO:1901363 - 0.000000000000000000000000000000009444 131.0
MMD2_k127_3989400_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000007313 112.0
MMD2_k127_3991053_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 357.0
MMD2_k127_3991053_1 redox protein, regulator of disulfide bond formation - - - 0.000000000000000000000000000000000000000000000001698 179.0
MMD2_k127_3991053_2 cobalamin synthesis protein, P47K - - - 0.00000000000000000000000000000000000000000001755 173.0
MMD2_k127_3991053_3 OsmC-like protein - - - 0.0000000000000000004601 93.0
MMD2_k127_3991053_4 PBS lyase K22221 - - 0.0000000004038 68.0
MMD2_k127_4002179_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1156.0
MMD2_k127_4002179_1 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 1.008e-318 981.0
MMD2_k127_4002179_2 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 433.0
MMD2_k127_4002179_3 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 416.0
MMD2_k127_4002179_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 383.0
MMD2_k127_4002179_5 Epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 309.0
MMD2_k127_4002179_6 O-methyltransferase K00588 - 2.1.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 265.0
MMD2_k127_4002179_7 Thrombospondin type 1 repeats - - - 0.000000000000000000000000000000000000000000000000000000000000002098 231.0
MMD2_k127_4002179_8 PFAM Transglycosylase-associated protein - - - 0.000000000000000000000004926 104.0
MMD2_k127_4002179_9 Recombinase - - - 0.00003017 46.0
MMD2_k127_4017746_0 Telomere recombination K04656 - - 3.032e-259 823.0
MMD2_k127_4017746_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 445.0
MMD2_k127_4017746_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 421.0
MMD2_k127_4017746_3 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 382.0
MMD2_k127_4017746_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 325.0
MMD2_k127_4017746_5 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000001209 236.0
MMD2_k127_4017746_6 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001477 224.0
MMD2_k127_4017746_7 nickel cation binding K04651,K19640 - - 0.000000000000000000000000000001186 124.0
MMD2_k127_4017746_8 YtxH-like protein - - - 0.00000000000000000000000000001498 121.0
MMD2_k127_4037901_0 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 471.0
MMD2_k127_4037901_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 347.0
MMD2_k127_4037901_2 Dehydrogenase K00248 - 1.3.8.1 0.0000001635 57.0
MMD2_k127_4091611_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 2.825e-221 694.0
MMD2_k127_4091611_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 3.841e-206 644.0
MMD2_k127_4091611_2 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
MMD2_k127_4091611_3 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000133 196.0
MMD2_k127_4115777_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001194 230.0
MMD2_k127_4115777_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000004447 205.0
MMD2_k127_4115777_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000008326 203.0
MMD2_k127_4122682_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.0 1158.0
MMD2_k127_4122682_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1116.0
MMD2_k127_4122682_2 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 351.0
MMD2_k127_4122682_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000000006723 237.0
MMD2_k127_4122682_4 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000000000002245 172.0
MMD2_k127_4122682_5 COG3086 Positive regulator of sigma E activity K03803 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.0000009965 56.0
MMD2_k127_4127677_0 oligosaccharyl transferase activity - - - 0.00000000000000000000000006459 124.0
MMD2_k127_4127677_1 TPR repeat Sel1-like repeat Tetratricopeptide TPR_3 Tetratricopeptide TPR_2 - - - 0.00004456 48.0
MMD2_k127_4148044_0 FMN binding - - - 2.674e-194 610.0
MMD2_k127_4148044_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 514.0
MMD2_k127_4148044_10 Belongs to the HesB IscA family K15724 - - 0.00000000000000000000000001443 112.0
MMD2_k127_4148044_11 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000019 105.0
MMD2_k127_4148044_12 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.000000000000000005439 92.0
MMD2_k127_4148044_14 Acetyltransferase (GNAT) domain - - - 0.00000186 57.0
MMD2_k127_4148044_15 Sporulation related domain K03749 - - 0.0005282 52.0
MMD2_k127_4148044_2 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 424.0
MMD2_k127_4148044_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 428.0
MMD2_k127_4148044_4 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 396.0
MMD2_k127_4148044_5 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 330.0
MMD2_k127_4148044_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000004093 206.0
MMD2_k127_4148044_7 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000006375 182.0
MMD2_k127_4148044_8 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000004169 177.0
MMD2_k127_4148044_9 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000005154 163.0
MMD2_k127_414821_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 314.0
MMD2_k127_414821_1 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000004071 238.0
MMD2_k127_414821_2 TIGRFAM iron-sulfur cluster binding protein - - - 0.0000000000000000000000000000000000000000000000000004483 191.0
MMD2_k127_414821_3 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.000000000000000000000006778 102.0
MMD2_k127_4153828_0 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 313.0
MMD2_k127_4153828_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002322 286.0
MMD2_k127_4153828_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000008316 128.0
MMD2_k127_4195179_0 alginic acid biosynthetic process - - - 2.036e-261 825.0
MMD2_k127_4195179_1 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 290.0
MMD2_k127_4195179_3 glycine betaine transport K05845,K05846 - - 0.0000000000000000000000000000000000000000005539 166.0
MMD2_k127_4220806_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 462.0
MMD2_k127_4220806_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 319.0
MMD2_k127_4220806_2 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000201 256.0
MMD2_k127_4220806_3 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000002819 258.0
MMD2_k127_4220806_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000001812 246.0
MMD2_k127_4220806_5 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000002714 234.0
MMD2_k127_4220806_6 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000004474 219.0
MMD2_k127_4220806_7 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000001505 158.0
MMD2_k127_4220806_8 Hydrolase, P-loop family K06925 - - 0.0000000000000000000000000006686 118.0
MMD2_k127_4220806_9 SMART Cold shock protein K03704 - - 0.00000000000000000000000001809 109.0
MMD2_k127_4222982_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 0.0 1019.0
MMD2_k127_4222982_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 565.0
MMD2_k127_4222982_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000001912 53.0
MMD2_k127_4224411_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 6.149e-241 760.0
MMD2_k127_4224411_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 1.885e-205 650.0
MMD2_k127_4224411_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 462.0
MMD2_k127_4224411_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000003328 118.0
MMD2_k127_4224411_4 - - - - 0.000000000613 66.0
MMD2_k127_4236332_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 338.0
MMD2_k127_4236332_1 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000001235 188.0
MMD2_k127_4236332_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000003229 187.0
MMD2_k127_4236332_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000001305 178.0
MMD2_k127_4236332_4 Universal stress protein family - - - 0.000000000001635 73.0
MMD2_k127_4244511_0 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 514.0
MMD2_k127_4244511_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 422.0
MMD2_k127_4246240_0 isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 416.0
MMD2_k127_4275790_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 425.0
MMD2_k127_4275790_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 374.0
MMD2_k127_4275790_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 GO:0003674,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090304,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 374.0
MMD2_k127_4275790_3 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000001949 261.0
MMD2_k127_4275790_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000005093 203.0
MMD2_k127_4275790_5 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000741 147.0
MMD2_k127_4275790_6 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000007243 93.0
MMD2_k127_4275790_7 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000002991 83.0
MMD2_k127_4275790_8 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000004967 81.0
MMD2_k127_4275790_9 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000006263 73.0
MMD2_k127_4277058_0 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003273 510.0
MMD2_k127_4277058_1 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.000000000000000000000000000000000000000000006349 165.0
MMD2_k127_4281107_0 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 4.494e-198 631.0
MMD2_k127_4281107_1 - - - - 0.000002137 51.0
MMD2_k127_4290489_0 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000009582 264.0
MMD2_k127_4290489_1 denitrification pathway K02569,K15876 - - 0.000000000000000000000000000000000003058 142.0
MMD2_k127_4290489_2 Negative regulator of sigma-B activity. Phosphorylates and inactivates its specific antagonist protein, RsbV. Upon phosphorylation of RsbV, RsbW is released and binds to sigma-B, thereby blocking its ability to form an RNA polymerase holoenzyme (E-sigma-B) K04757 - 2.7.11.1 0.000000004361 60.0
MMD2_k127_4331563_0 response regulator K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 408.0
MMD2_k127_4331563_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 355.0
MMD2_k127_4331563_10 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000001085 110.0
MMD2_k127_4331563_11 Protein of unknown function (DUF507) - - - 0.0000000000000000000000001643 109.0
MMD2_k127_4331563_12 Protein of unknown function (DUF507) - - - 0.000000000000000000000001097 105.0
MMD2_k127_4331563_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000007405 99.0
MMD2_k127_4331563_14 - - - - 0.000000003758 65.0
MMD2_k127_4331563_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 342.0
MMD2_k127_4331563_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
MMD2_k127_4331563_4 regulation of ruffle assembly - - - 0.000000000000000000000000000000000000000000000000000000001534 210.0
MMD2_k127_4331563_5 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000003251 220.0
MMD2_k127_4331563_6 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000001635 208.0
MMD2_k127_4331563_7 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000001063 173.0
MMD2_k127_4331563_8 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000005605 157.0
MMD2_k127_4331563_9 HNH nucleases - - - 0.000000000000000000000000000000000000007715 146.0
MMD2_k127_4332935_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 6.69e-223 700.0
MMD2_k127_4332935_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 548.0
MMD2_k127_4332935_10 Drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000003406 115.0
MMD2_k127_4332935_11 CheR methyltransferase, SAM binding domain K00575 - 2.1.1.80 0.000000000000000000000003579 105.0
MMD2_k127_4332935_12 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.000000000000001662 78.0
MMD2_k127_4332935_13 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 - - 0.00000645 52.0
MMD2_k127_4332935_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 467.0
MMD2_k127_4332935_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 432.0
MMD2_k127_4332935_4 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 412.0
MMD2_k127_4332935_5 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008276 298.0
MMD2_k127_4332935_6 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000001411 233.0
MMD2_k127_4332935_7 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000002029 193.0
MMD2_k127_4332935_8 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0000000000000000000000000000003698 127.0
MMD2_k127_4332935_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000006565 117.0
MMD2_k127_4337723_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004903 626.0
MMD2_k127_4382499_0 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 541.0
MMD2_k127_4382499_1 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007856 255.0
MMD2_k127_4382499_2 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000001086 243.0
MMD2_k127_4382499_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000006102 169.0
MMD2_k127_4382499_4 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000000000001827 170.0
MMD2_k127_4382499_5 Transketolase, central region K00615 - 2.2.1.1 0.00000000000000005706 81.0
MMD2_k127_4398500_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 302.0
MMD2_k127_4398500_1 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000204 157.0
MMD2_k127_4398500_2 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000006093 110.0
MMD2_k127_4409605_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 3.61e-281 876.0
MMD2_k127_4409605_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.888e-204 647.0
MMD2_k127_4409605_10 Copper-exporting ATPase K17686 - 3.6.3.54 0.0008731 44.0
MMD2_k127_4409605_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 407.0
MMD2_k127_4409605_3 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 407.0
MMD2_k127_4409605_4 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 338.0
MMD2_k127_4409605_5 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000001646 181.0
MMD2_k127_4409605_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000008728 153.0
MMD2_k127_4409605_7 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000003113 146.0
MMD2_k127_4409605_8 - - - - 0.00000000000000000000000006179 119.0
MMD2_k127_4409605_9 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000001871 89.0
MMD2_k127_4439402_0 DEAD DEAH box helicase K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 335.0
MMD2_k127_4439402_1 protein-disulfide reductase activity - - - 0.00000000000000000000000001226 115.0
MMD2_k127_4439402_2 - - - - 0.000000000005658 66.0
MMD2_k127_4448549_0 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 534.0
MMD2_k127_4448549_1 Transcriptional regulator K02529 - - 0.0000000000000000685 87.0
MMD2_k127_4448549_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0001499 45.0
MMD2_k127_4449016_0 PFAM Tetratricopeptide TPR_1 repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 400.0
MMD2_k127_4449016_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 365.0
MMD2_k127_4449016_2 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 365.0
MMD2_k127_4449016_3 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000044 234.0
MMD2_k127_4449016_4 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000001732 154.0
MMD2_k127_4449016_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000449 66.0
MMD2_k127_4479662_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 510.0
MMD2_k127_4479662_1 ABC1 family K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 305.0
MMD2_k127_4479662_2 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 287.0
MMD2_k127_4479662_3 - - - - 0.000002471 56.0
MMD2_k127_4484016_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 371.0
MMD2_k127_4484016_1 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.0000000000000000000000000000000000002777 147.0
MMD2_k127_4484016_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000005492 49.0
MMD2_k127_4515091_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 5.855e-220 688.0
MMD2_k127_4515091_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
MMD2_k127_4523995_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 526.0
MMD2_k127_4523995_1 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 363.0
MMD2_k127_4523995_2 Universal stress protein family - - - 0.00000006509 60.0
MMD2_k127_4523995_3 Belongs to the sulfur carrier protein TusA family - - - 0.00003017 46.0
MMD2_k127_4549143_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 608.0
MMD2_k127_4549143_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 412.0
MMD2_k127_4549143_2 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000004391 140.0
MMD2_k127_4632833_0 Belongs to the LDH MDH superfamily. LDH family K00016 - 1.1.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000001074 264.0
MMD2_k127_4632833_1 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000000000000000000000000000000000000000009506 201.0
MMD2_k127_4636180_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 5.912e-195 636.0
MMD2_k127_4649503_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 414.0
MMD2_k127_4649503_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000164 228.0
MMD2_k127_4649503_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000004661 55.0
MMD2_k127_4665231_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 1.495e-229 715.0
MMD2_k127_4665231_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 613.0
MMD2_k127_4665231_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 556.0
MMD2_k127_4665231_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009366 331.0
MMD2_k127_4665231_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000007281 160.0
MMD2_k127_4665231_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000005468 128.0
MMD2_k127_4665231_6 Transporter associated domain K03699,K06189 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000307 76.0
MMD2_k127_4726609_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 5.984e-241 758.0
MMD2_k127_4726609_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000007203 146.0
MMD2_k127_4728821_0 type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 490.0
MMD2_k127_4728821_1 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007889 400.0
MMD2_k127_4732601_0 - - - - 0.00000000000000000000000000000000000000000000000000000000004219 212.0
MMD2_k127_4732601_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000006295 121.0
MMD2_k127_4732601_2 Pyridine nucleotide-disulphide oxidoreductase K22405 - 1.6.3.4 0.00000007717 57.0
MMD2_k127_4754660_1 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000002725 249.0
MMD2_k127_4754660_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000002963 240.0
MMD2_k127_4754660_3 Predicted permease YjgP/YjgQ family K11720 - - 0.00000000000000000000000002155 120.0
MMD2_k127_4756922_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 519.0
MMD2_k127_4756922_1 DNA RNA helicase, superfamily II, SNF2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 329.0
MMD2_k127_4756922_2 Transposase IS116/IS110/IS902 family - - - 0.000000000000000000000000000000000000000000000000000000002811 204.0
MMD2_k127_4756922_3 Transposase IS116/IS110/IS902 family - - - 0.0000000000000859 74.0
MMD2_k127_4756922_4 COG3547 Transposase and inactivated derivatives - - - 0.0008138 45.0
MMD2_k127_4760135_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 505.0
MMD2_k127_4760135_1 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 427.0
MMD2_k127_4760135_11 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000004259 78.0
MMD2_k127_4760135_12 Class III cytochrome C family - - - 0.000000000000001298 83.0
MMD2_k127_4760135_13 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00008055 46.0
MMD2_k127_4760135_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 359.0
MMD2_k127_4760135_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 321.0
MMD2_k127_4760135_4 Pfam Anion-transporting ATPase K01551,K19171 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005762 285.0
MMD2_k127_4760135_5 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005224 290.0
MMD2_k127_4760135_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000002771 238.0
MMD2_k127_4760135_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004052 251.0
MMD2_k127_4760135_8 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000001405 195.0
MMD2_k127_4760135_9 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000004079 185.0
MMD2_k127_4760372_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 5.538e-218 690.0
MMD2_k127_4760372_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 342.0
MMD2_k127_4760372_2 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 317.0
MMD2_k127_4760372_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000003807 184.0
MMD2_k127_4760372_4 diguanylate cyclase - - - 0.00000000000000000000001242 102.0
MMD2_k127_4760372_5 PFAM Rubrerythrin - - - 0.00000000000000003534 87.0
MMD2_k127_4768149_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 617.0
MMD2_k127_4768149_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007584 451.0
MMD2_k127_4768149_2 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 308.0
MMD2_k127_4797219_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 573.0
MMD2_k127_4797219_1 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 369.0
MMD2_k127_4810120_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 436.0
MMD2_k127_4810120_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 388.0
MMD2_k127_4810120_2 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000000000003931 169.0
MMD2_k127_4810120_3 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.0000000000000000000575 90.0
MMD2_k127_4813352_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 414.0
MMD2_k127_4813352_1 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007209 278.0
MMD2_k127_4813352_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000007026 202.0
MMD2_k127_4821192_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 444.0
MMD2_k127_4821192_1 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 366.0
MMD2_k127_4821192_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044425,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.0000000000000000000000000000000000000000000000000000000000000005991 224.0
MMD2_k127_482724_0 Predicted permease K07089 - - 1.032e-230 730.0
MMD2_k127_482724_1 SMART Elongator protein 3 MiaB NifB K22226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 488.0
MMD2_k127_482724_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 308.0
MMD2_k127_482724_3 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000002265 201.0
MMD2_k127_482724_4 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000004377 171.0
MMD2_k127_483440_0 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 310.0
MMD2_k127_483440_1 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000004847 203.0
MMD2_k127_483440_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000003077 113.0
MMD2_k127_483440_4 Chemotaxis phosphatase CheX - - - 0.000000004458 62.0
MMD2_k127_4842244_0 Proton-conducting membrane transporter - - - 2.278e-259 815.0
MMD2_k127_4842244_1 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 1.924e-231 728.0
MMD2_k127_4842244_2 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009997 514.0
MMD2_k127_4842244_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 411.0
MMD2_k127_4842244_4 Hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001888 265.0
MMD2_k127_4842244_5 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000498 218.0
MMD2_k127_4842244_6 histidine kinase, HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000006175 213.0
MMD2_k127_4842244_7 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000005901 194.0
MMD2_k127_4842244_8 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000008026 178.0
MMD2_k127_4842244_9 - - - - 0.00000000000000000000000000000000000003664 162.0
MMD2_k127_4887026_0 Methyl-viologen-reducing hydrogenase, delta subunit K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.799e-319 990.0
MMD2_k127_4887026_1 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004759 272.0
MMD2_k127_4887806_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 341.0
MMD2_k127_4887806_1 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004827 254.0
MMD2_k127_4887806_2 PFAM MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000004144 216.0
MMD2_k127_4887806_3 TIGRFAM molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000000000000000000000003955 208.0
MMD2_k127_4887806_5 Regulatory protein, FmdB family - - - 0.000000000000000000000008865 102.0
MMD2_k127_4887806_6 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000002061 85.0
MMD2_k127_4887806_7 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000003135 78.0
MMD2_k127_4903092_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 363.0
MMD2_k127_4903092_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 326.0
MMD2_k127_4903092_10 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000008017 68.0
MMD2_k127_4903092_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 327.0
MMD2_k127_4903092_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001328 282.0
MMD2_k127_4903092_4 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000009285 234.0
MMD2_k127_4903092_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000003317 198.0
MMD2_k127_4903092_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000004336 183.0
MMD2_k127_4903092_7 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000002969 165.0
MMD2_k127_4903092_8 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000006024 166.0
MMD2_k127_4903092_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000002474 132.0
MMD2_k127_4940343_0 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000004152 166.0
MMD2_k127_4940343_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000224 151.0
MMD2_k127_4940343_2 TPR repeat - - - 0.000009757 57.0
MMD2_k127_4967949_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 302.0
MMD2_k127_4967949_2 HEAT repeats - - - 0.0000000000000000000000000000000000000000000000000008309 199.0
MMD2_k127_4967949_3 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000002443 98.0
MMD2_k127_4967949_5 protein secretion K03116,K03117 - - 0.0000000000008216 73.0
MMD2_k127_4973407_0 LysM domain K16291 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 350.0
MMD2_k127_4973407_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 296.0
MMD2_k127_4973407_2 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000000007511 249.0
MMD2_k127_4973407_3 PFAM TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000324 260.0
MMD2_k127_4973407_4 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000004023 224.0
MMD2_k127_4973407_5 ABC transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000003511 196.0
MMD2_k127_4973407_6 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000000000001374 183.0
MMD2_k127_4973407_8 PFAM LemA family protein K03744 - - 0.000000000001482 68.0
MMD2_k127_4975257_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 2.835e-211 676.0
MMD2_k127_4975257_1 Aldehyde dehydrogenase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 524.0
MMD2_k127_4975257_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 492.0
MMD2_k127_4975257_3 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005688 383.0
MMD2_k127_4975257_4 Heavy-metal-associated domain K17686 GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000126 230.0
MMD2_k127_4975257_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000001312 205.0
MMD2_k127_4975257_6 Transcriptional regulator - - - 0.0000009524 59.0
MMD2_k127_4985985_0 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 334.0
MMD2_k127_4985985_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 291.0
MMD2_k127_4985985_2 MlaD protein K02067 - - 0.000000000000000000001167 96.0
MMD2_k127_501142_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 606.0
MMD2_k127_501142_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 326.0
MMD2_k127_501142_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000004935 167.0
MMD2_k127_501142_3 - - - - 0.000000000000000000000000000000000000000001609 162.0
MMD2_k127_501142_4 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000000002746 142.0
MMD2_k127_501142_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.00000000000000000000000000000000007283 140.0
MMD2_k127_501142_6 - - - - 0.000000000000000000000000000000001807 134.0
MMD2_k127_501142_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000002236 92.0
MMD2_k127_5013735_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004301 327.0
MMD2_k127_5013735_1 Outer membrane lipoprotein - - - 0.000000000000000000000000000000000000000000002403 178.0
MMD2_k127_5013735_2 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000003182 148.0
MMD2_k127_5017567_0 CobQ CobB MinD ParA nucleotide binding domain K08252,K13661,K16554,K16692 - 2.7.10.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 538.0
MMD2_k127_5017567_1 polysaccharide export K01991 - - 0.00000000000000000000000000000000000000000000000000007933 199.0
MMD2_k127_5019018_0 Biotin-lipoyl like K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 322.0
MMD2_k127_5019018_1 transcriptional regulator - - - 0.0000000000000000000000000000000000001512 147.0
MMD2_k127_5028904_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1300.0
MMD2_k127_5028904_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 555.0
MMD2_k127_5028904_2 Ecdysteroid kinase K07102 - 2.7.1.221 0.00000000000000000000000000000004207 130.0
MMD2_k127_5062656_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 2.612e-228 729.0
MMD2_k127_5062656_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 5.108e-220 687.0
MMD2_k127_5062656_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 597.0
MMD2_k127_5062656_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 539.0
MMD2_k127_5062656_4 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 362.0
MMD2_k127_5062656_5 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
MMD2_k127_5062656_6 ThiS family K03636 - - 0.0000000000000000000000000000000001095 136.0
MMD2_k127_5062656_7 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000000000009562 124.0
MMD2_k127_5062656_8 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000008504 94.0
MMD2_k127_5062656_9 methionine transport K02071 - - 0.0000000000003898 74.0
MMD2_k127_5070388_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 1.05e-255 798.0
MMD2_k127_5070388_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 407.0
MMD2_k127_5070388_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 397.0
MMD2_k127_5070388_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000001208 210.0
MMD2_k127_5070388_4 YtkA-like - - - 0.000000000001633 72.0
MMD2_k127_5070388_5 Protein of unknown function with PCYCGC motif - - - 0.00000003718 59.0
MMD2_k127_507459_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.358e-224 708.0
MMD2_k127_507459_1 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000004222 222.0
MMD2_k127_5087977_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 401.0
MMD2_k127_5087977_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 368.0
MMD2_k127_5092971_0 trisaccharide binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 485.0
MMD2_k127_5100764_0 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 327.0
MMD2_k127_5100764_1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000003702 249.0
MMD2_k127_5100764_2 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.0000000000000000000000001645 118.0
MMD2_k127_5100764_3 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000002312 59.0
MMD2_k127_5102399_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 580.0
MMD2_k127_5102399_1 - - - - 0.0000000000317 65.0
MMD2_k127_5105183_0 Belongs to the aldehyde dehydrogenase family K13821 - 1.2.1.88,1.5.5.2 0.0 1060.0
MMD2_k127_5105183_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 456.0
MMD2_k127_5105183_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 445.0
MMD2_k127_5105183_3 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 435.0
MMD2_k127_5105183_4 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 415.0
MMD2_k127_5105183_5 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000003108 256.0
MMD2_k127_5105183_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000005566 246.0
MMD2_k127_5106381_0 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 346.0
MMD2_k127_5106381_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000193 275.0
MMD2_k127_5106381_2 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000002808 205.0
MMD2_k127_5106381_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000004797 126.0
MMD2_k127_5110271_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 1.931e-308 958.0
MMD2_k127_5110271_1 glycolate transport K14393 - - 8.22e-229 722.0
MMD2_k127_5110271_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 342.0
MMD2_k127_5110271_3 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004798 244.0
MMD2_k127_5110271_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000007775 127.0
MMD2_k127_5110271_5 Protein of unknown function, DUF485 - - - 0.000000000000000000000000009699 113.0
MMD2_k127_5110271_6 - - - - 0.0001428 50.0
MMD2_k127_5112520_0 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004614 398.0
MMD2_k127_5112520_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000001956 156.0
MMD2_k127_512492_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 5.708e-228 714.0
MMD2_k127_512492_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 411.0
MMD2_k127_512492_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000004775 157.0
MMD2_k127_512492_3 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000000000006546 150.0
MMD2_k127_5127438_0 GAF domain - - - 1.755e-196 656.0
MMD2_k127_5127438_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 545.0
MMD2_k127_5127438_2 Starch synthase catalytic domain K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 445.0
MMD2_k127_5127438_3 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 333.0
MMD2_k127_5128353_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 380.0
MMD2_k127_5128353_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000015 266.0
MMD2_k127_5130155_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000006047 162.0
MMD2_k127_5130155_1 Evidence 5 No homology to any previously reported sequences K03765 - - 0.00000000000004284 84.0
MMD2_k127_513960_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 8.614e-269 841.0
MMD2_k127_513960_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 560.0
MMD2_k127_513960_10 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.0000000000000000000000000000000000000000000000003856 186.0
MMD2_k127_513960_11 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000002984 170.0
MMD2_k127_513960_12 Ferredoxin K17992 - 1.12.1.3 0.0000000000000000000000000000000000000000001902 161.0
MMD2_k127_513960_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000000354 147.0
MMD2_k127_513960_14 phosphorelay signal transduction system K02437 - - 0.00000000000000000000000000001617 121.0
MMD2_k127_513960_15 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion - - - 0.000000000000000000000000002044 116.0
MMD2_k127_513960_16 DRTGG domain - - - 0.00000000000000000000000001149 112.0
MMD2_k127_513960_17 Transcriptional regulator, Crp Fnr family K10914 - - 0.000000000002551 73.0
MMD2_k127_513960_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336,K05299 - 1.17.1.10,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 556.0
MMD2_k127_513960_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 438.0
MMD2_k127_513960_4 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 349.0
MMD2_k127_513960_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 281.0
MMD2_k127_513960_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000298 221.0
MMD2_k127_513960_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000001862 200.0
MMD2_k127_513960_8 PFAM PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000000000000000001291 194.0
MMD2_k127_513960_9 ATPase histidine kinase DNA gyrase B HSP90 domain protein - - - 0.00000000000000000000000000000000000000000000000009022 183.0
MMD2_k127_5142773_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 403.0
MMD2_k127_5142773_1 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000005631 179.0
MMD2_k127_5142773_2 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000007329 129.0
MMD2_k127_5142773_3 -acetyltransferase - - - 0.000000003767 59.0
MMD2_k127_5142773_4 Universal stress protein - - - 0.0000006387 59.0
MMD2_k127_5142773_5 Nodulation protein S (NodS) - - - 0.00002397 49.0
MMD2_k127_517413_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 422.0
MMD2_k127_517413_1 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.000000000000000003218 87.0
MMD2_k127_5182447_0 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000002466 224.0
MMD2_k127_5182447_1 ABC transporter K01989 - - 0.00000000000000000000000000000000000000001224 166.0
MMD2_k127_5182447_2 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000008534 150.0
MMD2_k127_5182447_3 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000001018 137.0
MMD2_k127_5202371_0 - - - - 0.000000000000000000000000000000000000000000000000000227 192.0
MMD2_k127_5202371_1 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.000000000000000000000000000000000000000000000002795 179.0
MMD2_k127_5202371_2 Protein of unknown function (DUF4019) - - - 0.0000000000000000000000000000000000000000002201 166.0
MMD2_k127_5202371_3 IMP dehydrogenase activity K06041,K11527 - 2.7.13.3,5.3.1.13 0.0000000000000000000000000000000000006837 143.0
MMD2_k127_5202371_4 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000007657 102.0
MMD2_k127_5205525_0 PFAM Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 416.0
MMD2_k127_5205525_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000552 187.0
MMD2_k127_5205525_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000004941 159.0
MMD2_k127_5210034_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000005636 259.0
MMD2_k127_5210034_1 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000001295 183.0
MMD2_k127_5210034_2 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000005452 153.0
MMD2_k127_524651_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005629 564.0
MMD2_k127_524651_1 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 352.0
MMD2_k127_524651_2 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000004901 173.0
MMD2_k127_524651_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000003538 66.0
MMD2_k127_5248431_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006699 523.0
MMD2_k127_5248431_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004983 388.0
MMD2_k127_5248431_2 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000002761 192.0
MMD2_k127_5266194_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007301 584.0
MMD2_k127_5266194_1 YidE YbjL duplication K07085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 568.0
MMD2_k127_5266194_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 464.0
MMD2_k127_5266194_3 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 372.0
MMD2_k127_5266194_4 Ribosomal RNA adenine dimethylase - - - 0.0000000001032 70.0
MMD2_k127_5266194_5 - - - - 0.000000005181 59.0
MMD2_k127_5304906_0 4Fe-4S dicluster domain - - - 2.38e-252 781.0
MMD2_k127_5304906_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 544.0
MMD2_k127_5304906_2 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 353.0
MMD2_k127_5304906_3 - - - - 0.000000000000000000000000000000000000000000000000000006874 192.0
MMD2_k127_5304906_4 Universal stress protein family - - - 0.00000000000000000000000000000000000002192 148.0
MMD2_k127_5304906_5 4Fe-4S binding domain - - - 0.000000000000000008043 84.0
MMD2_k127_5304906_6 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000001036 63.0
MMD2_k127_5350974_0 Nitrate nitrite transporter K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 453.0
MMD2_k127_5350974_1 helix_turn_helix, cAMP Regulatory protein K10914,K21563 - - 0.0000000000000000000000000000007995 130.0
MMD2_k127_5350974_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000000149 110.0
MMD2_k127_5358832_0 FAD binding domain K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 616.0
MMD2_k127_5358832_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004424 470.0
MMD2_k127_5358832_2 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 442.0
MMD2_k127_5358832_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000002029 102.0
MMD2_k127_5377960_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 8.864e-215 676.0
MMD2_k127_5377960_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 374.0
MMD2_k127_5377960_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000001925 260.0
MMD2_k127_5377960_3 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000001845 126.0
MMD2_k127_5377960_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000004009 80.0
MMD2_k127_5377960_5 NusG domain II K00805 - 2.5.1.30 0.00000000000000697 79.0
MMD2_k127_5377960_6 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000009448 51.0
MMD2_k127_5380022_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1143.0
MMD2_k127_5380022_1 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.205e-256 812.0
MMD2_k127_5380022_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 567.0
MMD2_k127_5380022_3 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 449.0
MMD2_k127_5380022_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000009869 190.0
MMD2_k127_5380022_5 - - - - 0.00000000000000000000000000000000000000000000000002672 185.0
MMD2_k127_5380022_6 Membrane - - - 0.00000000000000000000000001956 116.0
MMD2_k127_5380022_7 YtxH-like protein - - - 0.00000000000000000189 89.0
MMD2_k127_5380022_8 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000008589 59.0
MMD2_k127_5380147_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1253.0
MMD2_k127_5380147_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 531.0
MMD2_k127_5380147_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 468.0
MMD2_k127_5380147_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000004684 195.0
MMD2_k127_5380147_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000001382 184.0
MMD2_k127_5380147_5 lysyltransferase activity K07027 - - 0.0000000000000000000000000000000000000000000000004427 186.0
MMD2_k127_5380147_6 AI-2E family transporter - - - 0.00000000000000000000000000000000004227 148.0
MMD2_k127_5380147_7 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000007648 121.0
MMD2_k127_5380147_8 NHL repeat - - - 0.00000000000000000000000001925 126.0
MMD2_k127_5380147_9 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000004404 90.0
MMD2_k127_5382041_0 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 546.0
MMD2_k127_541281_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 586.0
MMD2_k127_541281_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 525.0
MMD2_k127_541281_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 352.0
MMD2_k127_541281_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000111 283.0
MMD2_k127_5415321_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002711 593.0
MMD2_k127_5415321_1 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000002306 229.0
MMD2_k127_5415321_2 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00000000000000000000000000000000000005721 148.0
MMD2_k127_5415321_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001156 132.0
MMD2_k127_5415321_4 Ankyrin repeat protein - - - 0.000000000000001313 83.0
MMD2_k127_5415321_5 conserved protein, contains double-stranded beta-helix domain - - - 0.000008954 52.0
MMD2_k127_5452757_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009063 434.0
MMD2_k127_5452757_1 PFAM VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000005467 240.0
MMD2_k127_5452757_2 NUDIX domain K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000002635 169.0
MMD2_k127_5452757_3 PFAM Toluene tolerance K07323 - - 0.000000000000000000000000000000000007626 144.0
MMD2_k127_5465953_0 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 6.611e-279 874.0
MMD2_k127_5465953_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 498.0
MMD2_k127_5465953_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 280.0
MMD2_k127_5466676_0 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001187 270.0
MMD2_k127_5466676_1 with different specificities (related to short-chain alcohol K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000006066 259.0
MMD2_k127_5496605_0 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009215 520.0
MMD2_k127_5496605_1 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 403.0
MMD2_k127_5507666_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 610.0
MMD2_k127_5507666_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 292.0
MMD2_k127_5518853_0 PFAM glycosyl transferase, family 9 K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 410.0
MMD2_k127_5518853_1 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 406.0
MMD2_k127_5518853_2 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843,K02849 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 406.0
MMD2_k127_5518853_3 transferase activity, transferring glycosyl groups K02844 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 398.0
MMD2_k127_5518853_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 393.0
MMD2_k127_5518853_5 biosynthesis glycosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000863 300.0
MMD2_k127_5518853_6 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 281.0
MMD2_k127_5518853_7 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000001316 206.0
MMD2_k127_5518853_8 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000005383 196.0
MMD2_k127_5522445_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 561.0
MMD2_k127_5522445_1 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 383.0
MMD2_k127_553848_0 Alpha amylase, catalytic domain K06044 - 5.4.99.15 0.0 1240.0
MMD2_k127_553848_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0 1079.0
MMD2_k127_553848_2 alpha amylase, catalytic K01236 - 3.2.1.141 7.463e-246 775.0
MMD2_k127_553848_3 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 602.0
MMD2_k127_553848_4 Histidine kinase K07646 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002642 526.0
MMD2_k127_553848_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002293 248.0
MMD2_k127_5545985_0 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 309.0
MMD2_k127_5561237_0 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006001 320.0
MMD2_k127_5561237_1 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002083 281.0
MMD2_k127_5561237_2 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000144 258.0
MMD2_k127_5561237_3 STAS domain K04749 - - 0.00000000000000000000001102 104.0
MMD2_k127_5561237_4 anti-sigma regulatory factor K04757 - 2.7.11.1 0.0000000000000002613 84.0
MMD2_k127_5576057_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000006878 162.0
MMD2_k127_5576057_1 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15554 - - 0.0000000000000000000000000000000000000187 155.0
MMD2_k127_5576057_2 NMT1-like family - - - 0.000000000000000000000000000002102 134.0
MMD2_k127_5576057_3 OsmC-like protein - - - 0.00005153 47.0
MMD2_k127_5581934_0 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 313.0
MMD2_k127_5581934_1 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000000000000001121 234.0
MMD2_k127_5584541_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 598.0
MMD2_k127_5599745_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000001459 229.0
MMD2_k127_5599745_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000007785 213.0
MMD2_k127_5599745_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000002462 193.0
MMD2_k127_5599745_3 response regulator, receiver K07658 - - 0.0000000000000000000000000008909 120.0
MMD2_k127_5604040_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 1.775e-225 709.0
MMD2_k127_5604040_1 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 381.0
MMD2_k127_5604040_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 331.0
MMD2_k127_5604040_3 PFAM metal-dependent phosphohydrolase, HD sub domain K09163 - - 0.0000000000000000000000000000000000000000000000000000000000004 218.0
MMD2_k127_5604040_4 Preprotein translocase subunit K03210 - - 0.0000000000000000000000000000000000000003389 151.0
MMD2_k127_5604040_5 Protein of unknown function (DUF1009) K09949 - - 0.0004082 44.0
MMD2_k127_5610569_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009742 563.0
MMD2_k127_5610569_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 272.0
MMD2_k127_5610569_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000006326 271.0
MMD2_k127_5610569_3 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001138 248.0
MMD2_k127_5610569_4 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000000000000000005266 165.0
MMD2_k127_5610569_5 Protein of unknown function (DUF1622) - - - 0.00000000000000000000000000004406 120.0
MMD2_k127_5610569_6 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000003046 97.0
MMD2_k127_5620564_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 5.894e-199 628.0
MMD2_k127_5620564_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 591.0
MMD2_k127_5620564_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000001147 114.0
MMD2_k127_5620564_12 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000000000007059 103.0
MMD2_k127_5620564_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000008901 98.0
MMD2_k127_5620564_14 - - - - 0.00006445 51.0
MMD2_k127_5620564_2 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008281 591.0
MMD2_k127_5620564_3 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006547 451.0
MMD2_k127_5620564_4 Mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 356.0
MMD2_k127_5620564_5 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 340.0
MMD2_k127_5620564_6 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001568 254.0
MMD2_k127_5620564_7 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000002294 210.0
MMD2_k127_5620564_8 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000001956 209.0
MMD2_k127_5620564_9 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000005241 179.0
MMD2_k127_5628588_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000001523 233.0
MMD2_k127_5628588_1 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000004888 200.0
MMD2_k127_5628588_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000007603 85.0
MMD2_k127_5630479_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 323.0
MMD2_k127_5630479_1 - - - - 0.0000000000000000000000000001747 119.0
MMD2_k127_5630479_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000008374 82.0
MMD2_k127_5630479_3 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.000000000000005339 76.0
MMD2_k127_5630479_4 FixH - - - 0.00000000000001258 79.0
MMD2_k127_564170_1 - - - - 0.000000000235 69.0
MMD2_k127_564170_2 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.000000003101 57.0
MMD2_k127_564545_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 394.0
MMD2_k127_564545_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 329.0
MMD2_k127_564545_2 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 327.0
MMD2_k127_564545_3 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000001344 152.0
MMD2_k127_564545_4 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000007727 91.0
MMD2_k127_5686291_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 5.434e-194 613.0
MMD2_k127_5686291_1 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 300.0
MMD2_k127_5686291_10 domain-containing protein K09523 - - 0.0000000001449 66.0
MMD2_k127_5686291_12 Peptidase MA superfamily - - - 0.0007338 47.0
MMD2_k127_5686291_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000003003 246.0
MMD2_k127_5686291_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004025 233.0
MMD2_k127_5686291_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000000000000000000002153 153.0
MMD2_k127_5686291_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000008954 128.0
MMD2_k127_5686291_6 - - - - 0.00000000000000000000000006032 111.0
MMD2_k127_5686291_8 Protein of unknown function (DUF3187) - - - 0.000000000000000000001009 107.0
MMD2_k127_5686291_9 - - - - 0.00000000004992 67.0
MMD2_k127_5693155_0 Papain family cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000854 452.0
MMD2_k127_5693155_1 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000001681 151.0
MMD2_k127_5702280_0 Glycosyl hydrolases family 15 - - - 5.132e-249 786.0
MMD2_k127_5702280_1 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008592 229.0
MMD2_k127_5702280_2 electron transfer activity K00428 - 1.11.1.5 0.0000000000000000000000000007003 117.0
MMD2_k127_5702280_3 Belongs to the peptidase S1C family K04771,K04772 - 3.4.21.107 0.000000001622 61.0
MMD2_k127_5714218_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1206.0
MMD2_k127_5714218_1 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.00000000005582 63.0
MMD2_k127_5722123_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005791 450.0
MMD2_k127_5722123_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 411.0
MMD2_k127_5722123_2 GAF domain K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 342.0
MMD2_k127_5722123_3 metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003973 282.0
MMD2_k127_5722123_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000001302 191.0
MMD2_k127_5722123_5 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000007568 187.0
MMD2_k127_5722123_6 OsmC-like protein K07397 - - 0.000000000000000000000000000000000000000000000004758 178.0
MMD2_k127_5722123_7 4Fe-4S binding domain K07307 - - 0.00000000000000000000000000000000000000003847 158.0
MMD2_k127_5722123_8 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000005974 139.0
MMD2_k127_5722123_9 Belongs to the sulfur carrier protein TusA family - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.00000000000000000002316 94.0
MMD2_k127_5729532_0 NHL repeat containing protein - - - 0.000000000000000000000000000001285 130.0
MMD2_k127_5731144_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 354.0
MMD2_k127_5731144_1 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.00000000000000000000000000000000000000000007189 168.0
MMD2_k127_5732438_0 Ribosomal protein S1 K02945,K03527,K07571 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 571.0
MMD2_k127_5732438_1 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 326.0
MMD2_k127_5732438_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 321.0
MMD2_k127_5732438_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000196 235.0
MMD2_k127_5732438_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000003082 219.0
MMD2_k127_5732438_5 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000001956 116.0
MMD2_k127_5732438_6 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000006274 88.0
MMD2_k127_5732438_7 40-residue YVTN family beta-propeller repeat - - - 0.0000000000004052 74.0
MMD2_k127_5741832_0 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000001476 223.0
MMD2_k127_5741832_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000002606 96.0
MMD2_k127_5741832_2 - - - - 0.0005231 44.0
MMD2_k127_5764730_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 395.0
MMD2_k127_5764730_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 294.0
MMD2_k127_5764730_2 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000002716 227.0
MMD2_k127_5764730_3 Uncharacterised conserved protein (DUF2156) K01163 - - 0.000000000000000000000000000000000000000000008364 172.0
MMD2_k127_5764730_4 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000001205 168.0
MMD2_k127_5764730_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000007552 59.0
MMD2_k127_5764730_6 - - - - 0.0000003612 54.0
MMD2_k127_5775406_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 577.0
MMD2_k127_5775406_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000001675 156.0
MMD2_k127_5778966_0 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000002878 83.0
MMD2_k127_5778966_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000003918 74.0
MMD2_k127_5778966_2 Universal stress protein family - - - 0.000000000005334 73.0
MMD2_k127_5778966_3 Belongs to the universal stress protein A family - - - 0.000000008747 64.0
MMD2_k127_5778966_4 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.00000144 57.0
MMD2_k127_5785432_0 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006866 533.0
MMD2_k127_5785432_1 PFAM peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 416.0
MMD2_k127_5785432_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000001393 89.0
MMD2_k127_579108_0 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 479.0
MMD2_k127_579108_1 translation release factor activity - - - 0.00000000000000000000000000000000000005406 147.0
MMD2_k127_579108_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02584 - - 0.00000001795 57.0
MMD2_k127_5795380_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.439e-256 812.0
MMD2_k127_5795380_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008888 431.0
MMD2_k127_5795380_2 Transcriptional regulator, MerR family - - - 0.0000000000001811 72.0
MMD2_k127_5802336_0 argininosuccinate lyase K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004216 467.0
MMD2_k127_5802336_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 319.0
MMD2_k127_5807198_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 2.902e-246 766.0
MMD2_k127_5807198_1 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000000000000000000000000000000001059 139.0
MMD2_k127_5820533_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 507.0
MMD2_k127_5820533_1 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000004976 106.0
MMD2_k127_582443_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1179.0
MMD2_k127_582443_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 302.0
MMD2_k127_582443_2 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000001791 228.0
MMD2_k127_582443_3 Cation efflux family K16264 - - 0.0000000000000000001464 89.0
MMD2_k127_5834933_0 Hexapeptide repeat of succinyl-transferase - - - 4.281e-242 759.0
MMD2_k127_5834933_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 303.0
MMD2_k127_5853083_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 441.0
MMD2_k127_5853083_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 394.0
MMD2_k127_585371_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 442.0
MMD2_k127_585371_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 346.0
MMD2_k127_585371_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000003743 136.0
MMD2_k127_5857633_0 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 292.0
MMD2_k127_5857633_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009799 287.0
MMD2_k127_5857633_2 Pfam:TPM K08988 - - 0.00000000000000000000000000000000000000000000000000000003189 203.0
MMD2_k127_5857633_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000005428 182.0
MMD2_k127_5857633_4 protein histidine kinase activity - - - 0.000000000000000004347 93.0
MMD2_k127_586385_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 559.0
MMD2_k127_586385_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000823 544.0
MMD2_k127_586385_2 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 503.0
MMD2_k127_586385_3 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 436.0
MMD2_k127_586385_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000001932 212.0
MMD2_k127_586385_5 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000009621 173.0
MMD2_k127_586385_6 L-2-hydroxyglutarate dehydrogenase - GO:0000166,GO:0003674,GO:0003824,GO:0003973,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016899,GO:0036094,GO:0043167,GO:0043168,GO:0047545,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 - 0.000000000000000000000000000000007929 131.0
MMD2_k127_586385_7 Bacterial sugar transferase - - - 0.00000005923 55.0
MMD2_k127_5872015_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.71e-261 822.0
MMD2_k127_5872015_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.324e-222 705.0
MMD2_k127_5872015_10 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.000006201 51.0
MMD2_k127_5872015_2 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 580.0
MMD2_k127_5872015_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 444.0
MMD2_k127_5872015_4 Two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 434.0
MMD2_k127_5872015_5 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004007 386.0
MMD2_k127_5872015_6 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 319.0
MMD2_k127_5872015_7 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000001835 229.0
MMD2_k127_5872015_8 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000008015 153.0
MMD2_k127_5872015_9 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000002958 110.0
MMD2_k127_5878005_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 340.0
MMD2_k127_5878005_1 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000001515 227.0
MMD2_k127_5878005_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000001217 177.0
MMD2_k127_5878005_3 Universal stress protein family - - - 0.0000000000000000000000000000000000001366 146.0
MMD2_k127_5878005_4 proteolysis K03665 - - 0.000000000000000000000000000008209 124.0
MMD2_k127_5881656_0 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 561.0
MMD2_k127_5881656_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 465.0
MMD2_k127_5881656_2 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000007798 177.0
MMD2_k127_5885356_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 2.975e-275 866.0
MMD2_k127_5885356_1 4Fe-4S binding domain - - - 8.066e-225 706.0
MMD2_k127_5885356_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 410.0
MMD2_k127_5885356_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 377.0
MMD2_k127_5885356_4 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 299.0
MMD2_k127_5885356_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000002448 131.0
MMD2_k127_5885356_6 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479 - - 0.00000008294 59.0
MMD2_k127_58919_0 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005789 398.0
MMD2_k127_58919_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005738 388.0
MMD2_k127_5894041_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 547.0
MMD2_k127_5894041_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 474.0
MMD2_k127_5894041_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000007324 148.0
MMD2_k127_5907469_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003059 244.0
MMD2_k127_5907469_1 glyoxalase III activity - - - 0.00000000000000000000000000000000000000000009167 165.0
MMD2_k127_5907469_2 YCII-related domain - - - 0.0000000000000000000000001891 109.0
MMD2_k127_5907469_3 - - - - 0.0000000000000000000000002987 108.0
MMD2_k127_5907469_4 PFAM bifunctional deaminase-reductase domain protein - - - 0.00000000000000000000001158 102.0
MMD2_k127_5907469_6 Domain of unknown function (DU1801) - - - 0.000002375 54.0
MMD2_k127_5907665_0 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 439.0
MMD2_k127_5907665_1 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 335.0
MMD2_k127_5907665_2 histidine kinase HAMP region domain protein - - - 0.00000000000000000005725 92.0
MMD2_k127_5925068_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 466.0
MMD2_k127_5925068_1 TrkA-N domain K03455,K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 369.0
MMD2_k127_5925068_2 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 310.0
MMD2_k127_5925068_3 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000007108 136.0
MMD2_k127_5925068_4 Dienelactone hydrolase family - - - 0.000000000000000008985 83.0
MMD2_k127_5933913_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001985 281.0
MMD2_k127_5933913_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000004182 248.0
MMD2_k127_5933913_2 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000001163 207.0
MMD2_k127_5933913_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000002466 150.0
MMD2_k127_5933913_4 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000009084 132.0
MMD2_k127_5933913_6 Protein of unknown function (DUF1573) - - - 0.000004199 50.0
MMD2_k127_5933913_7 TonB C terminal K03646 - - 0.0002644 52.0
MMD2_k127_594239_0 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 295.0
MMD2_k127_594239_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000003593 129.0
MMD2_k127_594239_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000001376 121.0
MMD2_k127_5964276_0 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000304 209.0
MMD2_k127_5964276_1 PIN domain - - - 0.00000000000000000001865 96.0
MMD2_k127_5964276_2 Ribbon-helix-helix protein, copG family - - - 0.0007555 45.0
MMD2_k127_5972337_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 515.0
MMD2_k127_5972337_1 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 449.0
MMD2_k127_5972337_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002177 232.0
MMD2_k127_5972337_3 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.0000000000000000000000000000000000000000000000001346 179.0
MMD2_k127_5972337_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000000000001043 175.0
MMD2_k127_5972337_5 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000002668 142.0
MMD2_k127_5972337_6 lyase activity - - - 0.00000000000000000408 88.0
MMD2_k127_5972337_8 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.000000000007 65.0
MMD2_k127_5979108_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 511.0
MMD2_k127_5979108_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 390.0
MMD2_k127_5979108_2 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 293.0
MMD2_k127_5979108_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000002177 271.0
MMD2_k127_5979108_4 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002999 271.0
MMD2_k127_5979108_5 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000024 190.0
MMD2_k127_5979108_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000000513 189.0
MMD2_k127_5979108_7 OstA-like protein K09774 - - 0.00000000000000000000000000000006508 130.0
MMD2_k127_5979108_8 InterPro IPR010664 - - - 0.0009664 49.0
MMD2_k127_5982745_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 568.0
MMD2_k127_5982745_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 445.0
MMD2_k127_5982745_10 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000001625 193.0
MMD2_k127_5982745_11 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.000000000000000000000000000000000000000000000000000777 194.0
MMD2_k127_5982745_12 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000001971 144.0
MMD2_k127_5982745_13 Protein of unknown function (DUF1284) K09706 - - 0.00000000000000000000000000000001139 134.0
MMD2_k127_5982745_14 - - - - 0.00000000000000000000000000000001195 132.0
MMD2_k127_5982745_15 cheY-homologous receiver domain - - - 0.0007856 46.0
MMD2_k127_5982745_16 Tetratricopeptide repeat - - - 0.0009015 46.0
MMD2_k127_5982745_2 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 402.0
MMD2_k127_5982745_3 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 395.0
MMD2_k127_5982745_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 349.0
MMD2_k127_5982745_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 343.0
MMD2_k127_5982745_6 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002848 281.0
MMD2_k127_5982745_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000431 259.0
MMD2_k127_5982745_8 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000142 206.0
MMD2_k127_5982745_9 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000000000000001768 196.0
MMD2_k127_6001206_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 433.0
MMD2_k127_6001206_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 340.0
MMD2_k127_6001206_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000001295 183.0
MMD2_k127_6002258_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005028 391.0
MMD2_k127_6002258_1 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 298.0
MMD2_k127_6002258_2 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000000000000000000002156 210.0
MMD2_k127_6002258_3 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000005815 151.0
MMD2_k127_6002258_4 COG0526 Thiol-disulfide isomerase and thioredoxins K03672 - 1.8.1.8 0.000000000000003755 78.0
MMD2_k127_6002258_5 Thioredoxin K03672 - 1.8.1.8 0.00000001144 58.0
MMD2_k127_6013304_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 517.0
MMD2_k127_6013304_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 427.0
MMD2_k127_6013304_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 407.0
MMD2_k127_6013304_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002791 249.0
MMD2_k127_6013304_4 heat shock protein binding - - - 0.000000000000000000000000000000000000004147 158.0
MMD2_k127_6014816_0 spermidine synthase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 383.0
MMD2_k127_6014816_1 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000000001366 102.0
MMD2_k127_6017732_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 1.632e-254 806.0
MMD2_k127_6017732_1 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 338.0
MMD2_k127_6017732_2 PFAM cytochrome c assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 305.0
MMD2_k127_6017732_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000002644 263.0
MMD2_k127_6017732_4 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000000000000000000000000004673 157.0
MMD2_k127_6017732_5 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000003245 94.0
MMD2_k127_6027743_0 PFAM Type II secretion system protein E K02283,K03609 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 413.0
MMD2_k127_6027743_1 AAA domain K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006424 284.0
MMD2_k127_6054189_0 GAF domain K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 515.0
MMD2_k127_6054189_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 469.0
MMD2_k127_6054189_10 Pentapeptide repeats (9 copies) - - - 0.000000000000002824 83.0
MMD2_k127_6054189_2 Flavin containing amine oxidoreductase K01854 - 5.4.99.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000069 432.0
MMD2_k127_6054189_3 aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 362.0
MMD2_k127_6054189_4 Chemotaxis phosphatase CheX - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 308.0
MMD2_k127_6054189_5 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 302.0
MMD2_k127_6054189_6 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009277 263.0
MMD2_k127_6054189_7 FAD metabolic process K00953,K15429 GO:0003674,GO:0003824,GO:0003919,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0042726,GO:0042727,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046443,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0070566,GO:0071704,GO:0071944,GO:0072387,GO:0072388,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.228,2.7.7.2 0.00000000000000000000000000000000000000000000000000000002923 205.0
MMD2_k127_6054189_8 Peptidase S24-like K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000001995 204.0
MMD2_k127_6054189_9 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000001327 187.0
MMD2_k127_6056542_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.228e-237 745.0
MMD2_k127_6056542_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.067e-202 642.0
MMD2_k127_6056542_10 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000284 287.0
MMD2_k127_6056542_11 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000131 102.0
MMD2_k127_6056542_12 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.000000000000000144 81.0
MMD2_k127_6056542_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 580.0
MMD2_k127_6056542_3 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 565.0
MMD2_k127_6056542_4 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 484.0
MMD2_k127_6056542_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 449.0
MMD2_k127_6056542_6 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 435.0
MMD2_k127_6056542_7 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139,K18903 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 394.0
MMD2_k127_6056542_8 PFAM secretion protein HlyD family protein K01993,K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 375.0
MMD2_k127_6056542_9 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 323.0
MMD2_k127_6059615_0 calcium, potassium:sodium antiporter activity K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006932 271.0
MMD2_k127_6059615_1 AMP binding - - - 0.00000000000000000000000000000000000000001995 163.0
MMD2_k127_6059615_2 Thiamine-binding protein - - - 0.0000000000000000000000000000000001654 137.0
MMD2_k127_6059615_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000006155 123.0
MMD2_k127_6074788_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009903 571.0
MMD2_k127_6074788_1 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 0.00000000000000000000000000000000000000000000341 166.0
MMD2_k127_6074788_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000000005108 111.0
MMD2_k127_6074788_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00008313 52.0
MMD2_k127_6105580_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 4.505e-296 916.0
MMD2_k127_6105580_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 5.485e-213 668.0
MMD2_k127_6105580_2 TIGRFAM NADH-quinone oxidoreductase, chain G K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 606.0
MMD2_k127_6105580_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003528 338.0
MMD2_k127_6105580_4 Cytochrome b/b6/petB K00412,K03888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 327.0
MMD2_k127_6105580_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000001042 189.0
MMD2_k127_6105580_6 NADH dehydrogenase (ubiquinone) activity K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.00000000000000000000000000000000000000000004372 165.0
MMD2_k127_6105580_7 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000000005977 126.0
MMD2_k127_6105580_8 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000004453 79.0
MMD2_k127_6106014_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 370.0
MMD2_k127_6106014_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 304.0
MMD2_k127_6106014_2 Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000001637 227.0
MMD2_k127_6106014_3 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000004258 138.0
MMD2_k127_6106014_4 - - - - 0.000000000000001101 82.0
MMD2_k127_6108741_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 494.0
MMD2_k127_6108741_1 Mannose-6-phosphate isomerase, type K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 456.0
MMD2_k127_6108741_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004782 267.0
MMD2_k127_6124785_0 - - - - 0.000000000000000000000003244 107.0
MMD2_k127_6124785_1 4Fe-4S binding domain - - - 0.000000000000000000007719 95.0
MMD2_k127_6128111_0 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 602.0
MMD2_k127_6128111_1 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009895 287.0
MMD2_k127_6128111_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000002132 125.0
MMD2_k127_6128111_3 PAS domain K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000232 91.0
MMD2_k127_614130_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 451.0
MMD2_k127_614130_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007954 432.0
MMD2_k127_614130_2 HD domain - - - 0.0000000000000000002179 99.0
MMD2_k127_614130_3 - - - - 0.00000000000000009397 91.0
MMD2_k127_6155962_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 309.0
MMD2_k127_6155962_1 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000004675 170.0
MMD2_k127_6155962_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000006245 77.0
MMD2_k127_6187180_0 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001559 281.0
MMD2_k127_6187180_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000001594 217.0
MMD2_k127_6193068_0 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 449.0
MMD2_k127_6199771_0 O-Antigen ligase - - - 0.00000000000000000000000000000000000000000000000000001292 205.0
MMD2_k127_6199771_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000003533 160.0
MMD2_k127_6199771_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000002668 73.0
MMD2_k127_6216435_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 579.0
MMD2_k127_6216435_1 Actin K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000735 546.0
MMD2_k127_6216435_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 430.0
MMD2_k127_6216435_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000005292 132.0
MMD2_k127_6216435_4 RDD family - - - 0.000000000000000000000001388 107.0
MMD2_k127_6216435_5 rod shape-determining protein MreD K03571 - - 0.0001133 50.0
MMD2_k127_6243061_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 457.0
MMD2_k127_6243061_1 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000009496 203.0
MMD2_k127_6243061_2 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.00000000000000000000000000000005457 132.0
MMD2_k127_6263045_0 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 621.0
MMD2_k127_6263045_1 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 462.0
MMD2_k127_6263045_2 - - - - 0.00000000000000001362 88.0
MMD2_k127_636896_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000242 262.0
MMD2_k127_636896_1 COG1252 NADH dehydrogenase, FAD-containing subunit K03885 GO:0000166,GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0036094,GO:0042592,GO:0043167,GO:0043168,GO:0044237,GO:0044425,GO:0044464,GO:0045333,GO:0048037,GO:0048878,GO:0050136,GO:0050660,GO:0050662,GO:0050801,GO:0055065,GO:0055070,GO:0055076,GO:0055080,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0097159,GO:0098771,GO:0098796,GO:1901265,GO:1901363,GO:1902494 1.6.99.3 0.00000000000000000000000000000000000000000000000132 189.0
MMD2_k127_636896_2 Glutaredoxin - - - 0.000000002085 61.0
MMD2_k127_636896_3 Cupin domain - - - 0.000002231 52.0
MMD2_k127_643732_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 541.0
MMD2_k127_643732_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 371.0
MMD2_k127_643732_2 Uncharacterized ACR, COG1678 - - - 0.00000000000000000000000000000000000001421 154.0
MMD2_k127_643732_3 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.00000000000000000002686 94.0
MMD2_k127_643732_4 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.0000000000006593 71.0
MMD2_k127_648715_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.138e-279 874.0
MMD2_k127_648715_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 3.493e-198 623.0
MMD2_k127_648715_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 610.0
MMD2_k127_648715_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000003526 117.0
MMD2_k127_648715_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000006047 102.0
MMD2_k127_648715_5 PFAM ATP-grasp domain - - - 0.0000000000000002287 80.0
MMD2_k127_648715_6 DNA recombination-mediator protein A K04096 - - 0.00000001284 57.0
MMD2_k127_659163_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002128 549.0
MMD2_k127_659163_1 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000881 320.0
MMD2_k127_659163_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 309.0
MMD2_k127_659163_3 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.00000005072 57.0
MMD2_k127_679350_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 1.332e-226 709.0
MMD2_k127_679350_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 588.0
MMD2_k127_679350_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 307.0
MMD2_k127_679350_3 Dna alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001346 263.0
MMD2_k127_679350_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000007939 235.0
MMD2_k127_679350_5 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000002178 237.0
MMD2_k127_679350_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000004433 181.0
MMD2_k127_679350_7 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000004231 149.0
MMD2_k127_679350_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000001082 68.0
MMD2_k127_679350_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000003022 63.0
MMD2_k127_679864_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 372.0
MMD2_k127_679864_1 acetyltransferase - - - 0.0000000000000000000002375 103.0
MMD2_k127_692465_0 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003509 259.0
MMD2_k127_692465_1 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005698 249.0
MMD2_k127_692465_2 ABC 3 transport family K09816,K09819 - - 0.000000000000000000000000000000000000000000000000001198 189.0
MMD2_k127_692465_3 cell adhesion involved in biofilm formation - - - 0.00000000000000004616 83.0
MMD2_k127_714036_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001012 271.0
MMD2_k127_714036_1 SMART Signal transduction response regulator, receiver domain - - - 0.000000000000000000000000000000000000000007051 164.0
MMD2_k127_714036_2 PFAM Poly A polymerase head domain K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000001043 156.0
MMD2_k127_718122_0 Beta-lactamase - - - 1.225e-259 824.0
MMD2_k127_718122_1 Ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 434.0
MMD2_k127_718122_2 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 346.0
MMD2_k127_718122_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000004112 129.0
MMD2_k127_718122_4 ABC-type transport auxiliary lipoprotein component K09857 - - 0.0000000000000000000000000000009457 127.0
MMD2_k127_723481_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 294.0
MMD2_k127_723481_1 AAA domain, putative AbiEii toxin, Type IV TA system K02006 GO:0000041,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015675,GO:0016020,GO:0016021,GO:0030001,GO:0031224,GO:0032991,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.0000000000000000000000000000000000000000000000006297 181.0
MMD2_k127_723481_2 PFAM Cobalt transport protein K02008 - - 0.00000000000000000000000003782 121.0
MMD2_k127_72392_0 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002265 261.0
MMD2_k127_72392_1 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.00000000000000004537 81.0
MMD2_k127_72392_2 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000004976 68.0
MMD2_k127_745452_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001319 265.0
MMD2_k127_745452_1 lactate metabolic process K11473,K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000377 229.0
MMD2_k127_755464_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008302 499.0
MMD2_k127_755464_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 405.0
MMD2_k127_755464_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 345.0
MMD2_k127_762350_0 ABC transporter K06158 - - 4.786e-217 690.0
MMD2_k127_762350_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 492.0
MMD2_k127_762350_10 SMART Cold shock protein K03704 - - 0.000000000000000000000000004803 110.0
MMD2_k127_762350_11 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000001968 98.0
MMD2_k127_762350_12 - - - - 0.0000000000000001443 82.0
MMD2_k127_762350_2 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000000000000000000000000000000000007255 222.0
MMD2_k127_762350_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000002661 215.0
MMD2_k127_762350_4 CGGC - - - 0.0000000000000000000000000000000000000000000000000000000000007477 213.0
MMD2_k127_762350_5 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000000000000000000000000000000000001199 215.0
MMD2_k127_762350_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000008474 198.0
MMD2_k127_762350_7 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.000000000000000000000000000000000000000000000007785 178.0
MMD2_k127_762350_8 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000001066 172.0
MMD2_k127_762350_9 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000002559 145.0
MMD2_k127_764764_0 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.076e-285 903.0
MMD2_k127_764764_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 446.0
MMD2_k127_780285_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000004158 112.0
MMD2_k127_780285_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00002388 49.0
MMD2_k127_781005_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 1.484e-320 989.0
MMD2_k127_784475_0 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 387.0
MMD2_k127_784475_1 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000001732 104.0
MMD2_k127_784475_2 phosphorelay signal transduction system - - - 0.000000000000000000001312 96.0
MMD2_k127_787478_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 610.0
MMD2_k127_787478_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 533.0
MMD2_k127_787478_10 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000007221 226.0
MMD2_k127_787478_11 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000001301 196.0
MMD2_k127_787478_12 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.00000000000000000000000001016 109.0
MMD2_k127_787478_13 Cell wall formation K00075 - 1.3.1.98 0.00000000000000001622 87.0
MMD2_k127_787478_14 - - - - 0.00000000000476 72.0
MMD2_k127_787478_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 526.0
MMD2_k127_787478_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 454.0
MMD2_k127_787478_4 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 419.0
MMD2_k127_787478_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 397.0
MMD2_k127_787478_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 359.0
MMD2_k127_787478_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 324.0
MMD2_k127_787478_8 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 308.0
MMD2_k127_787478_9 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003383 267.0
MMD2_k127_800646_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 481.0
MMD2_k127_800646_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000001204 179.0
MMD2_k127_814491_0 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 532.0
MMD2_k127_814491_1 ribonuclease BN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 294.0
MMD2_k127_814491_2 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000002057 230.0
MMD2_k127_814491_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000006948 209.0
MMD2_k127_814491_4 PFAM thioesterase superfamily K02614 - - 0.0000000000000000000000000000000000000000002612 162.0
MMD2_k127_814491_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000002629 160.0
MMD2_k127_814491_6 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000001434 167.0
MMD2_k127_814491_7 phosphorelay signal transduction system - - - 0.0000000000000000000001358 106.0
MMD2_k127_814491_8 HEAT repeats - - - 0.000000000002165 80.0
MMD2_k127_833839_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006040,GO:0006047,GO:0006048,GO:0006139,GO:0006464,GO:0006468,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008966,GO:0009058,GO:0009225,GO:0009226,GO:0009987,GO:0016310,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019538,GO:0034641,GO:0034654,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046349,GO:0046483,GO:0046777,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901576 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000485 530.0
MMD2_k127_833839_1 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 374.0
MMD2_k127_833839_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 325.0
MMD2_k127_833839_3 YbbR-like protein - - - 0.00000000000000000000000000000000000000002543 162.0
MMD2_k127_833839_4 - - - - 0.0001063 47.0
MMD2_k127_847412_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 7.173e-259 813.0
MMD2_k127_847412_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 430.0
MMD2_k127_847412_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000007568 187.0
MMD2_k127_847412_3 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.00000000000000000000000000000000000000000000000037 177.0
MMD2_k127_847412_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000001527 160.0
MMD2_k127_847412_5 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000001984 151.0
MMD2_k127_847412_6 ATP-independent chaperone mediated protein folding - - - 0.00000008093 62.0
MMD2_k127_852021_0 - - - - 6.962e-249 779.0
MMD2_k127_852021_1 Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing - - - 0.000000000000000000000000000003241 123.0
MMD2_k127_876193_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1427.0
MMD2_k127_885686_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 603.0
MMD2_k127_885686_1 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 0.0000000000000000000000000000004274 123.0
MMD2_k127_887501_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006074 557.0
MMD2_k127_887501_1 6-phosphogluconate dehydrogenase (decarboxylating) K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004193 273.0
MMD2_k127_887501_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000001242 194.0
MMD2_k127_887501_3 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000003844 159.0
MMD2_k127_887501_4 Histidine kinase - - - 0.000000000000000001541 99.0
MMD2_k127_894297_0 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000002397 228.0
MMD2_k127_894297_1 PFAM ferredoxin thioredoxin reductase beta - - - 0.0000000000000000000000000000000000000000000001663 170.0
MMD2_k127_894297_2 Putative NAD(P)-binding K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000518 172.0
MMD2_k127_894297_3 PFAM Glutaredoxin K06191 - - 0.0000000000000000000000000000001236 124.0
MMD2_k127_894297_4 cheY-homologous receiver domain - - - 0.00000000000000000000000657 111.0
MMD2_k127_894297_5 BON domain - - - 0.0000000000000000000000222 107.0
MMD2_k127_894297_6 Tetratricopeptide repeat - - - 0.000000000003271 76.0
MMD2_k127_903219_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 586.0
MMD2_k127_903219_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 479.0
MMD2_k127_903219_10 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000008484 159.0
MMD2_k127_903219_11 carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000006112 116.0
MMD2_k127_903219_12 - - - - 0.0000000000000000000000004519 106.0
MMD2_k127_903219_13 - - - - 0.000000002946 59.0
MMD2_k127_903219_2 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 329.0
MMD2_k127_903219_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 310.0
MMD2_k127_903219_4 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003983 284.0
MMD2_k127_903219_5 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000001299 218.0
MMD2_k127_903219_6 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000003865 216.0
MMD2_k127_903219_7 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000007986 198.0
MMD2_k127_903219_8 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000001641 177.0
MMD2_k127_903219_9 Nitrogen fixation master sensor histidine kinase, PAS domain-containing K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000009382 179.0
MMD2_k127_903220_0 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000000000000000000000007174 202.0
MMD2_k127_903220_1 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000001675 188.0
MMD2_k127_903220_2 PFAM extracellular solute-binding protein family 1 K02040 - - 0.000000000000000000000000000000000000000000001653 174.0
MMD2_k127_910773_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.595e-253 787.0
MMD2_k127_910773_1 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 346.0
MMD2_k127_910773_2 Protein of unknown function (DUF2400) - - - 0.000000000000000000000000000000000000000000000000000004366 197.0
MMD2_k127_910773_3 N-terminal domain of cytochrome oxidase-cbb3, FixP - - - 0.0004688 46.0
MMD2_k127_946027_0 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005443 256.0
MMD2_k127_946027_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000002631 111.0
MMD2_k127_951117_0 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 512.0
MMD2_k127_951117_1 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 358.0
MMD2_k127_951117_2 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000003875 214.0
MMD2_k127_951117_3 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000005903 106.0
MMD2_k127_951117_4 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000001327 79.0
MMD2_k127_955536_0 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 322.0
MMD2_k127_955536_1 PFAM ResB family protein K07399 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009281 254.0
MMD2_k127_968738_0 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 398.0
MMD2_k127_968738_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 385.0
MMD2_k127_968738_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 321.0
MMD2_k127_968738_3 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 289.0
MMD2_k127_968738_4 ATPases associated with a variety of cellular activities - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000317 274.0
MMD2_k127_968738_5 PFAM CheW domain protein K03408 - - 0.00000000000000000005928 96.0
MMD2_k127_968738_6 Chemoreceptor zinc-binding domain K03406 - - 0.000000000000000001331 97.0
MMD2_k127_968738_7 PFAM response regulator receiver K03413 - - 0.00000000000000004151 90.0
MMD2_k127_968738_8 Chemotaxis sensory transducer K03406 - - 0.000000000000003698 77.0
MMD2_k127_968738_9 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000001914 63.0
MMD2_k127_968755_0 HEAT repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001028 276.0
MMD2_k127_968755_1 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000001163 133.0
MMD2_k127_968755_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000001873 110.0