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Overview

ID MAG02359
Name MMD2_bin.2
Sample SMP0059
Taxonomy
Kingdom Bacteria
Phylum WOR-3
Class WOR-3
Order SM23-42
Family DASVHD01
Genus
Species
Assembly information
Completeness (%) 90.93
Contamination (%) 0.5
GC content (%) 60.0
N50 (bp) 31,268
Genome size (bp) 2,795,060

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2223

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1053016_0 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000005812 208.0
MMD2_k127_1053016_1 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000000000000000000000000001629 220.0
MMD2_k127_1053016_2 S53, subtilisin kexin sedolisin - - - 0.0000000003061 74.0
MMD2_k127_1053016_3 Evidence 5 No homology to any previously reported sequences K07004,K09955 - - 0.000006327 60.0
MMD2_k127_108322_0 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 423.0
MMD2_k127_108322_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 419.0
MMD2_k127_108322_10 - - - - 0.00000000000006467 77.0
MMD2_k127_108322_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000005584 70.0
MMD2_k127_108322_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 332.0
MMD2_k127_108322_3 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 309.0
MMD2_k127_108322_4 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000002191 252.0
MMD2_k127_108322_5 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000003743 222.0
MMD2_k127_108322_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000001331 185.0
MMD2_k127_108322_7 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.0000000000000000000006467 105.0
MMD2_k127_108322_8 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000001348 92.0
MMD2_k127_108322_9 4fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000006049 82.0
MMD2_k127_1085570_0 FlgD Ig-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008873 459.0
MMD2_k127_1085570_1 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006797 393.0
MMD2_k127_1085570_2 PKD domain K07282 - - 0.00002534 52.0
MMD2_k127_1085570_3 Evidence 5 No homology to any previously reported sequences - - - 0.0001115 55.0
MMD2_k127_1564352_0 PFAM ABC transporter K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 327.0
MMD2_k127_1564352_1 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 305.0
MMD2_k127_1564352_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003488 274.0
MMD2_k127_1564352_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.0000000000000000000000000000000000000000395 161.0
MMD2_k127_1564352_4 PFAM ABC-2 type transporter K01992 - - 0.00000000000000004958 94.0
MMD2_k127_1619112_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 3.089e-200 631.0
MMD2_k127_1619112_1 metallopeptidase activity K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007434 604.0
MMD2_k127_1619112_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009808 332.0
MMD2_k127_1619112_11 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 290.0
MMD2_k127_1619112_12 tRNA processing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001436 263.0
MMD2_k127_1619112_13 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002957 251.0
MMD2_k127_1619112_14 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000001154 228.0
MMD2_k127_1619112_15 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000139 211.0
MMD2_k127_1619112_16 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000135 209.0
MMD2_k127_1619112_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000002181 190.0
MMD2_k127_1619112_18 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000003419 177.0
MMD2_k127_1619112_19 Galactose oxidase, central domain - - - 0.000000000000000000000000000000000000000000006536 178.0
MMD2_k127_1619112_2 elongation factor G K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 593.0
MMD2_k127_1619112_20 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000008296 171.0
MMD2_k127_1619112_21 - - - - 0.00000000000000000000000000000000000000001087 164.0
MMD2_k127_1619112_22 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000002462 156.0
MMD2_k127_1619112_23 Methyltransferase domain - - - 0.0000000000000000000000000000000000000005579 156.0
MMD2_k127_1619112_24 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.000000000000000000000000000000000001748 144.0
MMD2_k127_1619112_25 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000002487 148.0
MMD2_k127_1619112_26 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000006948 137.0
MMD2_k127_1619112_27 MgtC family K07507 - - 0.0000000000000000000000000000003545 127.0
MMD2_k127_1619112_28 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000638 124.0
MMD2_k127_1619112_29 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000004537 136.0
MMD2_k127_1619112_3 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 548.0
MMD2_k127_1619112_30 - - - - 0.000000000000000000000002193 109.0
MMD2_k127_1619112_31 Phosphotransferase enzyme family K17910 - 2.7.1.190 0.0000000000000000000005513 106.0
MMD2_k127_1619112_32 Mycolic acid cyclopropane synthetase - - - 0.000000000000000009321 93.0
MMD2_k127_1619112_33 SNARE-like domain protein - - - 0.00000000000000001967 91.0
MMD2_k127_1619112_34 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000001177 80.0
MMD2_k127_1619112_35 - - - - 0.0000000000000006341 83.0
MMD2_k127_1619112_36 - - - - 0.0000000000001266 82.0
MMD2_k127_1619112_37 YoaP-like - - - 0.00000000001088 74.0
MMD2_k127_1619112_38 Transcriptional regulator - - - 0.00000003788 63.0
MMD2_k127_1619112_4 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 542.0
MMD2_k127_1619112_40 bacterial-type flagellum-dependent cell motility - - - 0.000007601 59.0
MMD2_k127_1619112_41 amine dehydrogenase activity - - - 0.00003984 57.0
MMD2_k127_1619112_42 Laminin G domain - - - 0.0001073 55.0
MMD2_k127_1619112_43 bacterial-type flagellum-dependent cell motility - - - 0.0002259 53.0
MMD2_k127_1619112_5 Major Facilitator Superfamily K16210 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 439.0
MMD2_k127_1619112_6 metallopeptidase activity K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 418.0
MMD2_k127_1619112_7 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 362.0
MMD2_k127_1619112_8 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 359.0
MMD2_k127_1619112_9 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000538 323.0
MMD2_k127_1630706_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.174e-236 749.0
MMD2_k127_1630706_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 422.0
MMD2_k127_1630706_10 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000305 239.0
MMD2_k127_1630706_11 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000003594 245.0
MMD2_k127_1630706_12 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000707 236.0
MMD2_k127_1630706_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000007161 233.0
MMD2_k127_1630706_14 TIGRFAM hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000000000000000000000000000000005734 221.0
MMD2_k127_1630706_15 40-residue YVTN family beta-propeller repeat protein - - - 0.0000000000000000000000000000000000000000000000001446 202.0
MMD2_k127_1630706_16 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000001786 177.0
MMD2_k127_1630706_17 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000002125 140.0
MMD2_k127_1630706_18 Transposase IS200 like K07491 - - 0.000000000000000000001695 105.0
MMD2_k127_1630706_19 23S rRNA-intervening sequence protein - - - 0.0000000000000000007235 93.0
MMD2_k127_1630706_2 Alcohol dehydrogenase zinc-binding domain protein K13953,K18382 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 343.0
MMD2_k127_1630706_20 Bacterial transcription activator, effector binding domain K13652 - - 0.0000000000000004694 87.0
MMD2_k127_1630706_21 Yip1 domain - - - 0.00000000000000148 85.0
MMD2_k127_1630706_22 Outer membrane efflux protein K18904 - - 0.000000002296 69.0
MMD2_k127_1630706_23 cellulase activity - - - 0.00006831 55.0
MMD2_k127_1630706_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008494 305.0
MMD2_k127_1630706_4 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 313.0
MMD2_k127_1630706_5 binding-protein-dependent transport systems inner membrane component K02025,K15771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007515 300.0
MMD2_k127_1630706_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002081 279.0
MMD2_k127_1630706_7 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009094 263.0
MMD2_k127_1630706_8 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001506 255.0
MMD2_k127_1630706_9 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004177 249.0
MMD2_k127_1649257_0 von Willebrand factor, type A K07114 - - 3.058e-200 644.0
MMD2_k127_1649257_1 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 616.0
MMD2_k127_1649257_10 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 339.0
MMD2_k127_1649257_11 Chain length determinant protein K16692 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 326.0
MMD2_k127_1649257_12 Zinc-binding dehydrogenase K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001136 286.0
MMD2_k127_1649257_13 Protein of unknown function (DUF2723) K16928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000826 297.0
MMD2_k127_1649257_14 COG2909 ATP-dependent transcriptional regulator K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002823 295.0
MMD2_k127_1649257_15 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004172 271.0
MMD2_k127_1649257_16 Thiamine biosynthesis protein (ThiI) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003328 270.0
MMD2_k127_1649257_17 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000143 225.0
MMD2_k127_1649257_18 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000000000000000000000002135 207.0
MMD2_k127_1649257_19 TIGRFAM MazG family protein K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000006661 199.0
MMD2_k127_1649257_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 604.0
MMD2_k127_1649257_20 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000000000000000000000000000000000000000000009274 209.0
MMD2_k127_1649257_21 Permease YjgP YjgQ family protein K07091,K11720 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.00000000000000000000000000000000000000000000000000001368 212.0
MMD2_k127_1649257_22 asparaginase activity K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000008403 194.0
MMD2_k127_1649257_23 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000028 195.0
MMD2_k127_1649257_24 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000001285 192.0
MMD2_k127_1649257_25 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000006632 191.0
MMD2_k127_1649257_26 Phage-related replication protein - - - 0.000000000000000000000000000000000000000000007518 169.0
MMD2_k127_1649257_27 adenosine 5'-monophosphoramidase activity - - - 0.00000000000000000000000000000000000000000001429 166.0
MMD2_k127_1649257_28 Nodulation protein S (NodS) - - - 0.0000000000000000000000000000000000000000007078 163.0
MMD2_k127_1649257_29 Signal peptidase - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000003812 163.0
MMD2_k127_1649257_3 Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 482.0
MMD2_k127_1649257_30 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000005654 155.0
MMD2_k127_1649257_31 HD domain - - - 0.00000000000000000000000000000000000001199 151.0
MMD2_k127_1649257_32 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000000000000007997 144.0
MMD2_k127_1649257_33 PFAM PKD domain - - - 0.0000000000000000000000000000000004478 145.0
MMD2_k127_1649257_34 - - - - 0.0000000000000000000000000000001634 127.0
MMD2_k127_1649257_35 Methyltransferase domain - - - 0.00000000000000000000000000000666 125.0
MMD2_k127_1649257_36 Predicted permease YjgP/YjgQ family K11720 - - 0.0000000000000000000000000002067 128.0
MMD2_k127_1649257_37 - - - - 0.000000000000000000000000008583 115.0
MMD2_k127_1649257_38 BNR repeat-like domain - - - 0.00000000000000000000000001131 125.0
MMD2_k127_1649257_39 PKD domain - - - 0.0000000000000000000000007311 121.0
MMD2_k127_1649257_4 DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 477.0
MMD2_k127_1649257_40 Ribosomal RNA small subunit methyltransferase G K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000001401 111.0
MMD2_k127_1649257_41 guanyl-nucleotide exchange factor activity K01179,K03929,K09612,K12287,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.2.1.4,3.4.11.10,3.4.11.24,3.4.11.6 0.00000000000000000000006164 117.0
MMD2_k127_1649257_42 - - - - 0.0000000000000000000009662 112.0
MMD2_k127_1649257_43 Right handed beta helix region - - - 0.000000000000000000001263 109.0
MMD2_k127_1649257_44 4Fe-4S dicluster domain K03522,K05337 - - 0.00000000000000000003474 103.0
MMD2_k127_1649257_45 polysaccharide export K01991 - - 0.0000000000000000003933 94.0
MMD2_k127_1649257_46 Hep Hag repeat protein - - - 0.00000000000000001509 98.0
MMD2_k127_1649257_47 Soluble NSF attachment protein, SNAP - - - 0.00000000000002088 86.0
MMD2_k127_1649257_48 cellulose binding - - - 0.00000000000007749 82.0
MMD2_k127_1649257_49 Chromate resistance exported protein - - - 0.0000000000003462 72.0
MMD2_k127_1649257_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 450.0
MMD2_k127_1649257_50 Parallel beta-helix repeats - - - 0.0000000001028 74.0
MMD2_k127_1649257_51 - - - - 0.000000002233 67.0
MMD2_k127_1649257_53 LVIVD repeat K01179 - 3.2.1.4 0.00000002091 65.0
MMD2_k127_1649257_54 cellulose binding - - - 0.00000002116 67.0
MMD2_k127_1649257_55 Psort location Cytoplasmic, score - - - 0.000000111 59.0
MMD2_k127_1649257_56 Endonuclease I - - - 0.0000003496 63.0
MMD2_k127_1649257_57 von Willebrand factor, type A K07114 - - 0.00002308 50.0
MMD2_k127_1649257_58 - - - - 0.00002338 55.0
MMD2_k127_1649257_6 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 454.0
MMD2_k127_1649257_60 leucine-zipper of insertion element IS481 - - - 0.0000453 57.0
MMD2_k127_1649257_62 Peptidase family M28 K05994 - 3.4.11.10 0.00009894 49.0
MMD2_k127_1649257_63 protein secretion K20276 - - 0.0001092 56.0
MMD2_k127_1649257_64 alginic acid biosynthetic process - - - 0.0001366 53.0
MMD2_k127_1649257_65 Pkd domain containing protein - - - 0.0003509 52.0
MMD2_k127_1649257_7 PFAM proteinase inhibitor I4 serpin K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 391.0
MMD2_k127_1649257_8 PKD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 395.0
MMD2_k127_1649257_9 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 349.0
MMD2_k127_1664245_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 8.334e-215 678.0
MMD2_k127_1664245_1 glucosamine-6-phosphate deaminase activity K01057,K02564 - 3.1.1.31,3.5.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 306.0
MMD2_k127_1664245_2 NB-ARC domain - - - 0.0000000000000000000000002224 124.0
MMD2_k127_1664245_3 amine dehydrogenase activity - - - 0.000000000000002695 89.0
MMD2_k127_167141_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 9.791e-269 852.0
MMD2_k127_167141_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 3.088e-205 659.0
MMD2_k127_167141_10 PFAM Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000001242 199.0
MMD2_k127_167141_11 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000001962 119.0
MMD2_k127_167141_12 Transporter associated domain K03699 - - 0.0000000000000000000001224 109.0
MMD2_k127_167141_13 AsmA family K07289 - - 0.000000000000000001796 101.0
MMD2_k127_167141_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000008216 73.0
MMD2_k127_167141_15 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000008448 66.0
MMD2_k127_167141_16 PFAM Late competence development protein ComFB K02241 - - 0.00000000001272 72.0
MMD2_k127_167141_17 Tetratricopeptide repeat K09527 - - 0.000000000235 69.0
MMD2_k127_167141_18 - - - - 0.000000004215 63.0
MMD2_k127_167141_19 Tetratricopeptide repeat - - - 0.00000223 53.0
MMD2_k127_167141_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006275 473.0
MMD2_k127_167141_3 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 460.0
MMD2_k127_167141_4 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 344.0
MMD2_k127_167141_5 Phosphate starvation-inducible protein PhoH K06217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 304.0
MMD2_k127_167141_6 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000105 258.0
MMD2_k127_167141_7 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000001614 250.0
MMD2_k127_167141_8 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000002635 220.0
MMD2_k127_167141_9 tRNA nucleotidyltransferase poly(A) polymerase K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000001503 214.0
MMD2_k127_1678733_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1167.0
MMD2_k127_1678733_1 PFAM peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 478.0
MMD2_k127_1678733_10 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 289.0
MMD2_k127_1678733_11 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001078 283.0
MMD2_k127_1678733_12 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002208 245.0
MMD2_k127_1678733_13 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007399 267.0
MMD2_k127_1678733_14 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000003354 249.0
MMD2_k127_1678733_15 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000196 253.0
MMD2_k127_1678733_16 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000004284 260.0
MMD2_k127_1678733_17 GDP-mannose mannosyl hydrolase activity K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000003958 229.0
MMD2_k127_1678733_18 TIGRFAM 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000005487 224.0
MMD2_k127_1678733_19 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000004159 224.0
MMD2_k127_1678733_2 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 446.0
MMD2_k127_1678733_20 Transcriptional regulator K13652 - - 0.00000000000000000000000000000000000000000000000000000000000003381 226.0
MMD2_k127_1678733_21 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000001542 222.0
MMD2_k127_1678733_22 Belongs to the purine pyrimidine phosphoribosyltransferase family. PyrR subfamily K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000004951 216.0
MMD2_k127_1678733_23 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000008495 207.0
MMD2_k127_1678733_24 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000007557 201.0
MMD2_k127_1678733_25 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000000000000000000000368 198.0
MMD2_k127_1678733_26 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000004701 190.0
MMD2_k127_1678733_27 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000000000000005891 166.0
MMD2_k127_1678733_28 GGDEF domain - - - 0.00000000000000000000000000000000000000000005597 172.0
MMD2_k127_1678733_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 430.0
MMD2_k127_1678733_30 Protease prsW family - - - 0.000000000000000000000000000000000000000004474 165.0
MMD2_k127_1678733_31 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000004842 152.0
MMD2_k127_1678733_32 ABC-type transport system involved in multi-copper enzyme maturation, permease component - - - 0.0000000000000000000000000000000003655 141.0
MMD2_k127_1678733_33 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000137 133.0
MMD2_k127_1678733_34 GYD domain - - - 0.000000000000000000000000000000004776 130.0
MMD2_k127_1678733_35 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000573 134.0
MMD2_k127_1678733_36 Nucleoside 2-deoxyribosyltransferase - - - 0.0000000000000000000000000000001968 128.0
MMD2_k127_1678733_37 nucleotidyltransferase activity K07075 - - 0.00000000000000000000000000002382 124.0
MMD2_k127_1678733_38 pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000004886 123.0
MMD2_k127_1678733_39 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000000006943 110.0
MMD2_k127_1678733_4 PFAM Thiamine pyrophosphate K00170,K19071 - 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 391.0
MMD2_k127_1678733_40 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000007884 102.0
MMD2_k127_1678733_41 HEPN domain - - - 0.0000000000000000000003887 102.0
MMD2_k127_1678733_42 cellulose binding - - - 0.00000000000000000003216 104.0
MMD2_k127_1678733_43 Two component regulator propeller - - - 0.0000000000000001949 90.0
MMD2_k127_1678733_44 HAD-hyrolase-like K07025,K20862 - 3.1.3.102,3.1.3.104 0.0000000000000008754 86.0
MMD2_k127_1678733_45 Methyltransferase small domain - - - 0.000000000000001579 87.0
MMD2_k127_1678733_46 - - - - 0.000000000000009219 80.0
MMD2_k127_1678733_48 phosphorylase activity K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.000000000006638 69.0
MMD2_k127_1678733_49 2'-5' RNA ligase superfamily - - - 0.0000000000806 70.0
MMD2_k127_1678733_5 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 385.0
MMD2_k127_1678733_50 translation initiation factor activity K06996 - - 0.0000000001029 67.0
MMD2_k127_1678733_52 Tetratricopeptide TPR_2 repeat protein - - - 0.00005549 53.0
MMD2_k127_1678733_6 Belongs to the ATCase OTCase family K00608,K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 363.0
MMD2_k127_1678733_7 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 353.0
MMD2_k127_1678733_8 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 333.0
MMD2_k127_1678733_9 Protein conserved in bacteria K09927 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 316.0
MMD2_k127_1679445_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006871 263.0
MMD2_k127_1679445_1 Streptomycin adenylyltransferase K05593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001727 248.0
MMD2_k127_1679445_2 - - - - 0.000000000000000000000000000001518 121.0
MMD2_k127_1679445_3 PKD domain - - - 0.000000000000000000001507 106.0
MMD2_k127_1679445_5 PKD domain - - - 0.0008199 48.0
MMD2_k127_1695141_0 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 331.0
MMD2_k127_1695141_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 304.0
MMD2_k127_1695141_10 LVIVD repeat K01179 - 3.2.1.4 0.000000000001325 82.0
MMD2_k127_1695141_12 - - - - 0.000000000001997 80.0
MMD2_k127_1695141_13 exo-alpha-(2->6)-sialidase activity - - - 0.0000000001091 74.0
MMD2_k127_1695141_14 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00002792 49.0
MMD2_k127_1695141_15 Pyridoxamine 5'-phosphate oxidase - - - 0.00004968 51.0
MMD2_k127_1695141_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001406 234.0
MMD2_k127_1695141_3 PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000002712 167.0
MMD2_k127_1695141_4 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000001767 149.0
MMD2_k127_1695141_5 Serine protease family S08A. Source PGD - - - 0.0000000000000000000000000000000006262 153.0
MMD2_k127_1695141_6 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.00000000000000000000000000001557 132.0
MMD2_k127_1695141_7 - - - - 0.000000000000000000000002391 118.0
MMD2_k127_1695141_8 beta-lactamase domain protein - - - 0.000000000000000004067 97.0
MMD2_k127_1695141_9 Bacterial transcriptional activator domain K03556 - - 0.000000000000003628 90.0
MMD2_k127_1706503_0 Trypsin K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 381.0
MMD2_k127_1706503_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000177 242.0
MMD2_k127_1706503_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000002449 212.0
MMD2_k127_1706503_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000001344 210.0
MMD2_k127_1706503_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000001235 185.0
MMD2_k127_1706503_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000001629 154.0
MMD2_k127_1706503_6 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000001246 158.0
MMD2_k127_1706503_7 Signal transduction histidine kinase - - - 0.0000000000000000003518 93.0
MMD2_k127_1718160_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 499.0
MMD2_k127_1718160_1 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000001909 271.0
MMD2_k127_1718160_10 Prokaryotic N-terminal methylation motif - - - 0.0004277 49.0
MMD2_k127_1718160_2 Immune inhibitor A peptidase M6 K09607 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.00000000000000000000000000000000000000000000000000000000000000000000000715 264.0
MMD2_k127_1718160_3 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000008252 210.0
MMD2_k127_1718160_4 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000001122 168.0
MMD2_k127_1718160_5 PFAM Major Facilitator Superfamily K19576 - - 0.00000000000000000000000000000000000000000005729 173.0
MMD2_k127_1718160_6 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000003204 147.0
MMD2_k127_1718160_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000003467 143.0
MMD2_k127_1718160_8 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000001797 136.0
MMD2_k127_1730677_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 1.3e-260 820.0
MMD2_k127_1730677_1 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 7.429e-210 670.0
MMD2_k127_1730677_10 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 366.0
MMD2_k127_1730677_11 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 349.0
MMD2_k127_1730677_12 Biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 309.0
MMD2_k127_1730677_13 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000041 289.0
MMD2_k127_1730677_14 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001429 280.0
MMD2_k127_1730677_15 IMP cyclohydrolase-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002025 278.0
MMD2_k127_1730677_16 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000001896 231.0
MMD2_k127_1730677_17 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000002017 236.0
MMD2_k127_1730677_18 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000003175 251.0
MMD2_k127_1730677_19 Cytochrome C biogenesis protein K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000003194 233.0
MMD2_k127_1730677_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 2.192e-196 627.0
MMD2_k127_1730677_20 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.0000000000000000000000000000000000000000000003247 173.0
MMD2_k127_1730677_21 Belongs to the ompA family - - - 0.00000000000000000000000000001837 136.0
MMD2_k127_1730677_22 MotA/TolQ/ExbB proton channel family K03561,K03562 - - 0.00000000000000000000000000003279 125.0
MMD2_k127_1730677_23 PKD domain - - - 0.00000000000000000000000656 113.0
MMD2_k127_1730677_24 Redox-active disulfide protein - - - 0.0000000000000000000004741 98.0
MMD2_k127_1730677_25 PFAM Thioredoxin K03671 - - 0.00000000000000000000137 105.0
MMD2_k127_1730677_26 PFAM Tetratricopeptide - - - 0.0000000000000000004755 103.0
MMD2_k127_1730677_27 Biopolymer transport protein K03560 - - 0.00000000000000001362 88.0
MMD2_k127_1730677_28 PFAM NADPH-dependent FMN reductase - - - 0.000000000000001266 85.0
MMD2_k127_1730677_29 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000001598 76.0
MMD2_k127_1730677_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 520.0
MMD2_k127_1730677_30 regulatory protein, arsR K03892 - - 0.0000000000004734 73.0
MMD2_k127_1730677_31 penicillin-binding protein - - - 0.00000000001537 78.0
MMD2_k127_1730677_32 guanyl-nucleotide exchange factor activity - - - 0.0000000001294 73.0
MMD2_k127_1730677_33 PFAM Thioredoxin K03671 - - 0.0000000002552 69.0
MMD2_k127_1730677_34 Polymer-forming cytoskeletal - - - 0.000000003333 69.0
MMD2_k127_1730677_35 ompA family - - - 0.0000001252 63.0
MMD2_k127_1730677_36 energy transducer activity K03646,K03832 - - 0.0000004239 62.0
MMD2_k127_1730677_37 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0001275 48.0
MMD2_k127_1730677_38 Cytochrome c - - - 0.0003664 53.0
MMD2_k127_1730677_39 Putative zinc-finger - GO:0005575,GO:0016020 - 0.0008163 48.0
MMD2_k127_1730677_4 PFAM Bile acid sodium symporter K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 496.0
MMD2_k127_1730677_5 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 496.0
MMD2_k127_1730677_6 Histidine kinase K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 477.0
MMD2_k127_1730677_7 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 442.0
MMD2_k127_1730677_8 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 415.0
MMD2_k127_1730677_9 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 401.0
MMD2_k127_1765282_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 377.0
MMD2_k127_1765282_1 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 379.0
MMD2_k127_1765282_2 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 316.0
MMD2_k127_1765282_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000706 268.0
MMD2_k127_1765282_4 Tetratricopeptide repeat - - - 0.00000000000000000002442 101.0
MMD2_k127_1765282_5 Colicin V production protein K03558 - - 0.0004832 49.0
MMD2_k127_1821618_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000712 307.0
MMD2_k127_1821618_1 PFAM PKD domain containing protein - - - 0.0000000000002092 78.0
MMD2_k127_1821618_3 cellulose binding - - - 0.000001314 61.0
MMD2_k127_1949344_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 583.0
MMD2_k127_1949344_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
MMD2_k127_1949344_10 Peptidase family C25 - - - 0.000006303 59.0
MMD2_k127_1949344_11 cellulose binding K00505 - 1.14.18.1 0.000007292 60.0
MMD2_k127_1949344_12 Pkd domain containing protein - - - 0.00001265 59.0
MMD2_k127_1949344_13 Phospholipase/Carboxylesterase - - - 0.00003632 53.0
MMD2_k127_1949344_2 phosphatase activity K07025,K20862 - 3.1.3.102,3.1.3.104 0.00000000000000000000000000000000000000000000000000000004325 204.0
MMD2_k127_1949344_3 NHL repeat containing protein - - - 0.000000000000000000000000000135 132.0
MMD2_k127_1949344_4 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000002477 113.0
MMD2_k127_1949344_5 Protein of unknown function (DUF2089) - - - 0.000000000000000000000002778 106.0
MMD2_k127_1949344_6 - - - - 0.0000000000000001415 86.0
MMD2_k127_1949344_7 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000000005399 89.0
MMD2_k127_1949344_8 PKD domain K07282 - - 0.000000000000193 72.0
MMD2_k127_1949344_9 - - - - 0.00000000007153 72.0
MMD2_k127_1989909_0 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008091 253.0
MMD2_k127_2037675_0 Large extracellular alpha-helical protein K06894 - - 0.0 1207.0
MMD2_k127_2037675_1 Aldehyde dehydrogenase family K00141,K22187 - 1.2.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006375 587.0
MMD2_k127_2037675_10 Hep Hag repeat protein K01406,K21449 - 3.4.24.40 0.0000000000000000008023 102.0
MMD2_k127_2037675_11 PBS lyase HEAT domain protein repeat-containing protein K22221 - - 0.000000001122 70.0
MMD2_k127_2037675_13 Roadblock/LC7 domain K07131 - - 0.0004444 48.0
MMD2_k127_2037675_2 Aminotransferase class-III K00823,K03918,K20428 - 2.6.1.19,2.6.1.33,2.6.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 531.0
MMD2_k127_2037675_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 355.0
MMD2_k127_2037675_4 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000008305 221.0
MMD2_k127_2037675_5 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000009723 212.0
MMD2_k127_2037675_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000003944 195.0
MMD2_k127_2037675_7 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000002167 195.0
MMD2_k127_2037675_8 - - - - 0.0000000000000000000000000000000000000000000001184 184.0
MMD2_k127_2037675_9 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000002006 123.0
MMD2_k127_2045276_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.055e-238 751.0
MMD2_k127_2045276_1 DEAD H associated K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 353.0
MMD2_k127_2045276_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000004911 216.0
MMD2_k127_2045276_11 N-terminal domain of unknown function (DUF4140) - - - 0.000000000000000000000000000000000000000000000000001857 201.0
MMD2_k127_2045276_12 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000007804 177.0
MMD2_k127_2045276_13 - - - - 0.000000000000000000000000000000000000000000007176 181.0
MMD2_k127_2045276_14 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000003708 163.0
MMD2_k127_2045276_15 cerebellar Purkinje cell layer development K10442 GO:0000151,GO:0003674,GO:0003779,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006996,GO:0007010,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007610,GO:0007626,GO:0007628,GO:0008092,GO:0008150,GO:0008344,GO:0009987,GO:0016043,GO:0016358,GO:0021549,GO:0021680,GO:0021695,GO:0022008,GO:0022037,GO:0030029,GO:0030030,GO:0030036,GO:0030154,GO:0030182,GO:0030425,GO:0030534,GO:0030902,GO:0031175,GO:0031461,GO:0031463,GO:0032501,GO:0032502,GO:0032991,GO:0036477,GO:0042995,GO:0043005,GO:0043025,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044297,GO:0044424,GO:0044463,GO:0044464,GO:0048468,GO:0048513,GO:0048666,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0060322,GO:0071840,GO:0090659,GO:0097447,GO:0097458,GO:0120025,GO:0120036,GO:0120038,GO:1902494,GO:1990234 - 0.000000000000000000000000000000000000003946 159.0
MMD2_k127_2045276_16 Kelch motif - - - 0.00000000000000000000000000000000000002053 167.0
MMD2_k127_2045276_17 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 0.00000000000000000000000000000000001187 151.0
MMD2_k127_2045276_18 PFAM Transposase IS200 like K07491 - - 0.000000000000000000000000000002726 128.0
MMD2_k127_2045276_2 P-loop Domain of unknown function (DUF2791) K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 342.0
MMD2_k127_2045276_20 Divalent cation tolerance protein K03926 - - 0.0000000000000000000001227 101.0
MMD2_k127_2045276_21 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000005595 95.0
MMD2_k127_2045276_22 serine-type endopeptidase activity K04771 - 3.4.21.107 0.000000000002549 80.0
MMD2_k127_2045276_23 Aerotolerance regulator N-terminal - - - 0.00000005165 66.0
MMD2_k127_2045276_24 - - - - 0.00003746 53.0
MMD2_k127_2045276_25 PFAM FecR protein - - - 0.00003793 54.0
MMD2_k127_2045276_26 Parallel beta-helix repeats - - - 0.00004033 58.0
MMD2_k127_2045276_27 cellulose binding K00505 - 1.14.18.1 0.00004721 48.0
MMD2_k127_2045276_28 Proprotein convertase P-domain - - - 0.00004976 57.0
MMD2_k127_2045276_29 - - - - 0.0003425 54.0
MMD2_k127_2045276_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 325.0
MMD2_k127_2045276_4 UDP-glucose 4-epimerase activity K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009718 322.0
MMD2_k127_2045276_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 301.0
MMD2_k127_2045276_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006436 312.0
MMD2_k127_2045276_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001382 293.0
MMD2_k127_2045276_8 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000001509 238.0
MMD2_k127_2045276_9 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000005126 203.0
MMD2_k127_2078545_0 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000009297 77.0
MMD2_k127_211041_0 Ferritin-like domain - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 287.0
MMD2_k127_211041_1 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003042 289.0
MMD2_k127_211041_10 PFAM CheW domain protein K03408 - - 0.000000000000001401 82.0
MMD2_k127_211041_11 Tetratricopeptide repeat - - - 0.0000000001219 74.0
MMD2_k127_211041_2 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000001937 199.0
MMD2_k127_211041_3 PFAM response regulator receiver K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000002464 175.0
MMD2_k127_211041_4 CheC-like family K03410 - - 0.00000000000000000000000000000000000000000000001565 177.0
MMD2_k127_211041_5 TPR Domain containing protein K12600 - - 0.00000000000000000000000000000000000000000001219 186.0
MMD2_k127_211041_6 cell redox homeostasis K02199 - - 0.000000000000000000000000000000000008839 144.0
MMD2_k127_211041_7 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000172 135.0
MMD2_k127_211041_8 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000003708 119.0
MMD2_k127_211041_9 NifU-like domain - - - 0.000000000000000000000004576 103.0
MMD2_k127_2145267_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1083.0
MMD2_k127_2145267_1 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1021.0
MMD2_k127_2145267_10 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 391.0
MMD2_k127_2145267_11 NAT, N-acetyltransferase, of N-acetylglutamate synthase K22478 - 2.3.1.1,2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 333.0
MMD2_k127_2145267_12 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 309.0
MMD2_k127_2145267_13 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 317.0
MMD2_k127_2145267_14 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004511 283.0
MMD2_k127_2145267_15 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009655 273.0
MMD2_k127_2145267_16 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001715 271.0
MMD2_k127_2145267_17 Responsible for synthesis of pseudouridine from uracil K06177,K06180 GO:0000027,GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022607,GO:0022613,GO:0022618,GO:0031118,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 5.4.99.23,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002454 276.0
MMD2_k127_2145267_18 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000003345 272.0
MMD2_k127_2145267_19 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000004501 239.0
MMD2_k127_2145267_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.836e-235 766.0
MMD2_k127_2145267_20 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000111 229.0
MMD2_k127_2145267_21 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000001654 208.0
MMD2_k127_2145267_22 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000002652 220.0
MMD2_k127_2145267_23 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000000000006418 195.0
MMD2_k127_2145267_24 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.00000000000000000000000000000000000000000002732 165.0
MMD2_k127_2145267_25 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000005113 178.0
MMD2_k127_2145267_26 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000001516 162.0
MMD2_k127_2145267_27 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000003263 162.0
MMD2_k127_2145267_28 outer membrane efflux protein - - - 0.0000000000000000000000000000000000006096 156.0
MMD2_k127_2145267_29 Outer membrane efflux protein - - - 0.00000000000000000000000000000000003151 150.0
MMD2_k127_2145267_3 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 6.257e-232 746.0
MMD2_k127_2145267_30 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000005067 136.0
MMD2_k127_2145267_31 serine-type aminopeptidase activity - - - 0.0000000000000000000000000000000633 138.0
MMD2_k127_2145267_32 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000007522 133.0
MMD2_k127_2145267_33 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000006319 123.0
MMD2_k127_2145267_34 Polymer-forming cytoskeletal - - - 0.0000000000000000000008498 99.0
MMD2_k127_2145267_35 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000005261 92.0
MMD2_k127_2145267_36 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000003215 87.0
MMD2_k127_2145267_37 Winged helix-turn-helix domain (DUF2582) - - - 0.000000000006926 68.0
MMD2_k127_2145267_38 Putative zinc-finger - - - 0.0000002296 59.0
MMD2_k127_2145267_39 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.000008079 55.0
MMD2_k127_2145267_4 DNA polymerase X family K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 623.0
MMD2_k127_2145267_40 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00002959 54.0
MMD2_k127_2145267_5 FAD dependent oxidoreductase K00123,K00184,K00205,K00335,K00336,K00362,K02573,K05927,K18006,K18332 - 1.12.1.2,1.12.1.3,1.12.5.1,1.17.1.9,1.6.5.3,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 554.0
MMD2_k127_2145267_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 456.0
MMD2_k127_2145267_7 Belongs to the ATCase OTCase family K09065 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0043857,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 413.0
MMD2_k127_2145267_8 sarcosine oxidase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005075 411.0
MMD2_k127_2145267_9 Arginosuccinate synthase K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 398.0
MMD2_k127_2220860_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1089.0
MMD2_k127_2220860_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 435.0
MMD2_k127_2220860_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002825 297.0
MMD2_k127_2220860_3 Cache_2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001642 277.0
MMD2_k127_2220860_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000002175 152.0
MMD2_k127_2220860_5 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29 0.000000000000000000000000000000006356 143.0
MMD2_k127_2220860_6 Tetratricopeptide repeats - - - 0.000000001763 64.0
MMD2_k127_225807_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.686e-243 762.0
MMD2_k127_225807_1 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 601.0
MMD2_k127_225807_10 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001393 141.0
MMD2_k127_225807_11 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000002537 130.0
MMD2_k127_225807_14 Putative regulatory protein - - - 0.0000000000000000000002184 100.0
MMD2_k127_225807_15 peptidyl-tyrosine sulfation K07114 - - 0.00000000000000000001508 100.0
MMD2_k127_225807_16 cytochrome complex assembly K02198,K02200,K04016,K04017,K04018 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009897,GO:0009986,GO:0009987,GO:0015035,GO:0015036,GO:0016020,GO:0016043,GO:0016491,GO:0016667,GO:0017003,GO:0017004,GO:0017006,GO:0018063,GO:0018193,GO:0018198,GO:0018378,GO:0019538,GO:0022607,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071944,GO:0098552,GO:0098567,GO:1901564 - 0.0000000000000000009413 98.0
MMD2_k127_225807_17 PFAM glycoside hydrolase, family 10 - - - 0.00000001992 67.0
MMD2_k127_225807_18 cellulose binding - - - 0.000004667 59.0
MMD2_k127_225807_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 552.0
MMD2_k127_225807_3 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 448.0
MMD2_k127_225807_4 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 317.0
MMD2_k127_225807_5 Oxygen tolerance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 306.0
MMD2_k127_225807_6 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003913 263.0
MMD2_k127_225807_7 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000007183 244.0
MMD2_k127_225807_8 ABC-type multidrug transport system ATPase and permease K18890 - - 0.0000000000000000000000000000000000000000000000000000000000000004117 235.0
MMD2_k127_225807_9 TIGRFAM signal peptidase I K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000007922 188.0
MMD2_k127_2273272_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001303 274.0
MMD2_k127_2273272_1 peptidylprolyl isomerase K03771 - 5.2.1.8 0.00000000000000000008654 100.0
MMD2_k127_2273272_2 GIY-YIG catalytic domain - - - 0.000000000000001587 78.0
MMD2_k127_2302725_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 467.0
MMD2_k127_2302725_1 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00973,K04042,K16881 - 2.3.1.157,2.7.7.13,2.7.7.23,2.7.7.24,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002282 287.0
MMD2_k127_2302725_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000003864 101.0
MMD2_k127_2302725_11 PFAM S23 ribosomal protein - - - 0.0000004108 57.0
MMD2_k127_2302725_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000516 224.0
MMD2_k127_2302725_3 PFAM 3-dehydroquinate synthase K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000001238 199.0
MMD2_k127_2302725_4 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000007277 190.0
MMD2_k127_2302725_5 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000001498 178.0
MMD2_k127_2302725_6 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000001155 169.0
MMD2_k127_2302725_7 COG1943 Transposase and inactivated derivatives - - - 0.000000000000000000000000002761 122.0
MMD2_k127_2302725_8 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000005791 111.0
MMD2_k127_2302725_9 proteolysis K03665 - - 0.000000000000000000001162 102.0
MMD2_k127_2303706_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0002682,GO:0002684,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006950,GO:0008150,GO:0009314,GO:0009380,GO:0009605,GO:0009607,GO:0009628,GO:0016020,GO:0032991,GO:0035821,GO:0042802,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0071944,GO:0075136,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 3.923e-259 814.0
MMD2_k127_2303706_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 437.0
MMD2_k127_2303706_10 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008244 285.0
MMD2_k127_2303706_11 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002307 269.0
MMD2_k127_2303706_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000372 276.0
MMD2_k127_2303706_13 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000476 261.0
MMD2_k127_2303706_14 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000001372 261.0
MMD2_k127_2303706_15 Belongs to the glycosyl hydrolase 13 family K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000005446 264.0
MMD2_k127_2303706_16 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000001586 252.0
MMD2_k127_2303706_17 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000001425 239.0
MMD2_k127_2303706_18 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000005238 224.0
MMD2_k127_2303706_19 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000001691 226.0
MMD2_k127_2303706_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007248 438.0
MMD2_k127_2303706_20 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000003948 230.0
MMD2_k127_2303706_21 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000001509 219.0
MMD2_k127_2303706_22 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000001512 209.0
MMD2_k127_2303706_23 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000003895 181.0
MMD2_k127_2303706_24 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000002027 179.0
MMD2_k127_2303706_25 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000131 174.0
MMD2_k127_2303706_26 kelch-like K10448 GO:0000003,GO:0000151,GO:0000902,GO:0001894,GO:0003006,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006919,GO:0007275,GO:0007276,GO:0007281,GO:0007283,GO:0007286,GO:0007291,GO:0007349,GO:0007548,GO:0008150,GO:0008152,GO:0008406,GO:0008584,GO:0009566,GO:0009653,GO:0009887,GO:0009893,GO:0009987,GO:0010604,GO:0010941,GO:0010942,GO:0010950,GO:0010952,GO:0016043,GO:0016567,GO:0019222,GO:0019538,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030162,GO:0030539,GO:0031323,GO:0031325,GO:0031461,GO:0031463,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0032504,GO:0032989,GO:0032991,GO:0035112,GO:0036211,GO:0042592,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043170,GO:0043280,GO:0043281,GO:0043412,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0044703,GO:0045137,GO:0045862,GO:0046546,GO:0046661,GO:0048232,GO:0048468,GO:0048513,GO:0048515,GO:0048518,GO:0048522,GO:0048608,GO:0048609,GO:0048646,GO:0048731,GO:0048806,GO:0048808,GO:0048856,GO:0048869,GO:0048871,GO:0048872,GO:0048873,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051704,GO:0052547,GO:0052548,GO:0060249,GO:0060255,GO:0061458,GO:0065007,GO:0065008,GO:0065009,GO:0070647,GO:0071704,GO:0071840,GO:0080090,GO:0090598,GO:1901564,GO:1902494,GO:1990234,GO:2000116,GO:2001056 - 0.000000000000000000000002056 120.0
MMD2_k127_2303706_27 arabinogalactan endo-1,4-beta-galactosidase activity K01224 - 3.2.1.89 0.0000005641 63.0
MMD2_k127_2303706_28 Domain of unknown function DUF11 - - - 0.000007986 59.0
MMD2_k127_2303706_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 379.0
MMD2_k127_2303706_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 375.0
MMD2_k127_2303706_5 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 357.0
MMD2_k127_2303706_6 Penicillin-binding Protein dimerisation domain K03587,K08384,K08724,K12552,K12556 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008144,GO:0008150,GO:0008658,GO:0008955,GO:0009987,GO:0016020,GO:0016021,GO:0016740,GO:0016757,GO:0016758,GO:0031224,GO:0031226,GO:0031406,GO:0032153,GO:0033218,GO:0033293,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043177,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:1901363,GO:1901681 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 318.0
MMD2_k127_2303706_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006852 298.0
MMD2_k127_2303706_8 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 287.0
MMD2_k127_2303706_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 300.0
MMD2_k127_2329753_0 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000003668 191.0
MMD2_k127_2329753_1 protein related to plant photosystem II stability assembly factor - - - 0.00000000000000000000000000000005226 142.0
MMD2_k127_2329753_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000001176 126.0
MMD2_k127_2385665_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 288.0
MMD2_k127_2385665_1 - - - - 0.000000000000000000000000000000000000000000000000000000002072 215.0
MMD2_k127_2385665_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00003657 46.0
MMD2_k127_2385903_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567,K04568 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004812,GO:0004824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006430,GO:0006518,GO:0006520,GO:0006629,GO:0006644,GO:0006650,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009405,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019637,GO:0019752,GO:0030312,GO:0030322,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0040007,GO:0042221,GO:0042391,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046471,GO:0046483,GO:0046486,GO:0046677,GO:0046872,GO:0050896,GO:0051704,GO:0065007,GO:0065008,GO:0071704,GO:0071944,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 521.0
MMD2_k127_2385903_1 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003867 313.0
MMD2_k127_2385903_10 - - - - 0.0005311 42.0
MMD2_k127_2385903_2 ATP:guanido phosphotransferase, C-terminal catalytic domain K00933,K00934,K19405 GO:0006950,GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0046688,GO:0050896,GO:0097501,GO:1990169,GO:1990170 2.7.14.1,2.7.3.2,2.7.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001411 289.0
MMD2_k127_2385903_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.0000000000000000000000000000000000000000000000000000000000007001 218.0
MMD2_k127_2385903_4 cell adhesion involved in biofilm formation - - - 0.00000000000000000000000000000000000000000000000000000004974 214.0
MMD2_k127_2385903_5 lactate oxidation - - - 0.00000000000000000000000000000000001788 139.0
MMD2_k127_2385903_6 Peptidase family M28 K05994 - 3.4.11.10 0.00000000000000000000000325 119.0
MMD2_k127_2385903_7 PFAM UvrB uvrC K19411 - - 0.00000000000000000000001446 106.0
MMD2_k127_2385903_8 EnpEP protein - - - 0.000000000000000004098 98.0
MMD2_k127_2385903_9 extracellular matrix structural constituent - - - 0.00000001123 68.0
MMD2_k127_2400787_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 454.0
MMD2_k127_2400787_1 Chromate resistance - - - 0.0000000000000000000000000000000000000000004426 163.0
MMD2_k127_2400787_2 domain, Protein K14645 - - 0.00001687 55.0
MMD2_k127_2400787_3 domain, Protein - - - 0.0005807 50.0
MMD2_k127_2400787_4 - - - - 0.0008038 46.0
MMD2_k127_2434236_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 584.0
MMD2_k127_2434236_1 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 381.0
MMD2_k127_2434236_10 alpha-L-arabinofuranosidase - - - 0.000004939 59.0
MMD2_k127_2434236_11 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00003416 54.0
MMD2_k127_2434236_2 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004432 270.0
MMD2_k127_2434236_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000002164 224.0
MMD2_k127_2434236_4 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000499 208.0
MMD2_k127_2434236_5 Alpha amylase, catalytic domain - - - 0.0000000000000000000000000000000000198 142.0
MMD2_k127_2434236_6 Peptidase, M23 - - - 0.0000000000000000000000000000000002059 143.0
MMD2_k127_2434236_7 - - - - 0.00000000000000003161 93.0
MMD2_k127_2434236_8 PBS lyase HEAT-like repeat - - - 0.0000000009241 72.0
MMD2_k127_2434236_9 amine dehydrogenase activity - - - 0.000000002593 68.0
MMD2_k127_2524268_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000001546 207.0
MMD2_k127_2524268_1 pectinesterase activity K10117 - - 0.000000007141 69.0
MMD2_k127_2588153_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 3.544e-215 678.0
MMD2_k127_2588153_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 1.208e-205 663.0
MMD2_k127_2588153_10 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000000000003627 195.0
MMD2_k127_2588153_11 extracellular polysaccharide biosynthetic process K01153,K05789,K07011,K16554 - 3.1.21.3 0.00000000000000000000000000000000000000000000000004032 194.0
MMD2_k127_2588153_12 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000001939 183.0
MMD2_k127_2588153_13 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000003397 168.0
MMD2_k127_2588153_14 TrkA-C domain K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000001031 155.0
MMD2_k127_2588153_15 PTS system, Lactose/Cellobiose specific IIB subunit K02768,K02769,K02770 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008643,GO:0009401,GO:0015144,GO:0016020,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0034219,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0090563 2.7.1.202 0.00000000000000000000000001001 114.0
MMD2_k127_2588153_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000001642 121.0
MMD2_k127_2588153_17 TIGRFAM TonB family protein K03832 - - 0.0000000000000000004344 97.0
MMD2_k127_2588153_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000001114 89.0
MMD2_k127_2588153_2 Transglycosylase K05366 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 514.0
MMD2_k127_2588153_20 PFAM Tetratricopeptide repeat - - - 0.00000000000000000156 99.0
MMD2_k127_2588153_21 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000005839 87.0
MMD2_k127_2588153_22 biopolymer transport protein K03559 - - 0.0000000000000006043 85.0
MMD2_k127_2588153_23 Outer membrane transport energization protein ExbD - - - 0.00000000000006218 80.0
MMD2_k127_2588153_24 Gram-negative bacterial TonB protein C-terminal - - - 0.00000000001058 75.0
MMD2_k127_2588153_25 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000004367 72.0
MMD2_k127_2588153_27 methyltransferase activity - - - 0.0000002176 59.0
MMD2_k127_2588153_28 Binds directly to 16S ribosomal RNA K02968 - - 0.00000509 53.0
MMD2_k127_2588153_3 ATPases associated with a variety of cellular activities K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 390.0
MMD2_k127_2588153_4 polysaccharide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004116 399.0
MMD2_k127_2588153_5 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009435 337.0
MMD2_k127_2588153_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 316.0
MMD2_k127_2588153_7 PFAM Glycosyl transferase family 2 K16557 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000004291 233.0
MMD2_k127_2588153_8 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000001972 231.0
MMD2_k127_2588153_9 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000001482 204.0
MMD2_k127_262267_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 600.0
MMD2_k127_262267_1 SMART Metal-dependent phosphohydrolase, HD region - - - 0.00000000000000000000000000000000000000000000000000000000000000000009861 252.0
MMD2_k127_262267_2 Lysine exporter protein LysE YggA - - - 0.0000000000000000000000000000000000000000000000000000001843 202.0
MMD2_k127_262267_3 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000001615 192.0
MMD2_k127_262267_4 Pyrophosphatase K06019 - 3.6.1.1 0.0000000000000000000243 98.0
MMD2_k127_262267_5 PFAM Surface antigen variable number repeat K07277 - - 0.0000002061 62.0
MMD2_k127_2630851_0 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 590.0
MMD2_k127_2630851_1 L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000622 551.0
MMD2_k127_2630851_10 Domain of unknown function (DUF4438) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 415.0
MMD2_k127_2630851_11 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 403.0
MMD2_k127_2630851_12 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003885 409.0
MMD2_k127_2630851_13 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 392.0
MMD2_k127_2630851_14 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 396.0
MMD2_k127_2630851_15 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 395.0
MMD2_k127_2630851_16 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005934 396.0
MMD2_k127_2630851_17 Zinc transporter K07238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000949 351.0
MMD2_k127_2630851_18 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009572 355.0
MMD2_k127_2630851_19 Uncharacterised ACR (DUF711) K09157 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 344.0
MMD2_k127_2630851_2 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 526.0
MMD2_k127_2630851_20 mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 320.0
MMD2_k127_2630851_21 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 314.0
MMD2_k127_2630851_22 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 306.0
MMD2_k127_2630851_23 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 313.0
MMD2_k127_2630851_24 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000991 289.0
MMD2_k127_2630851_25 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001618 303.0
MMD2_k127_2630851_26 WG containing repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001746 289.0
MMD2_k127_2630851_27 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004475 275.0
MMD2_k127_2630851_28 metal ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004059 252.0
MMD2_k127_2630851_29 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000021 247.0
MMD2_k127_2630851_3 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 499.0
MMD2_k127_2630851_30 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000097 256.0
MMD2_k127_2630851_31 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000003971 240.0
MMD2_k127_2630851_32 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.00000000000000000000000000000000000000000000000000000000000000001364 245.0
MMD2_k127_2630851_33 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.00000000000000000000000000000000000000000000000000000000000000001942 240.0
MMD2_k127_2630851_34 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000003144 229.0
MMD2_k127_2630851_35 (Rhomboid) family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000002985 228.0
MMD2_k127_2630851_36 PFAM metal-dependent phosphohydrolase HD sub domain K06951 - - 0.000000000000000000000000000000000000000000000000000000000000000908 223.0
MMD2_k127_2630851_37 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000000000001101 216.0
MMD2_k127_2630851_38 diguanylate cyclase K02030,K06950,K16923 - - 0.000000000000000000000000000000000000000000000000000000000009705 230.0
MMD2_k127_2630851_39 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000001149 232.0
MMD2_k127_2630851_4 Xylose isomerase-like TIM barrel K01805 - 5.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 498.0
MMD2_k127_2630851_40 lyase activity K01387,K03301 - 3.4.24.3 0.0000000000000000000000000000000000000000000000000000002493 216.0
MMD2_k127_2630851_41 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000004182 198.0
MMD2_k127_2630851_42 Class II Aldolase and Adducin N-terminal domain K01629 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0009056,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0019321,GO:0019323,GO:0044238,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0071704,GO:1901575 4.1.2.19 0.00000000000000000000000000000000000000000000000002853 188.0
MMD2_k127_2630851_43 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K12143 - - 0.00000000000000000000000000000000000000000000003902 176.0
MMD2_k127_2630851_44 Belongs to the peptidase S24 family K03503 - - 0.00000000000000000000000000000000000000000000009208 186.0
MMD2_k127_2630851_45 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000002455 169.0
MMD2_k127_2630851_46 Subtilase family - - - 0.000000000000000000000000000000000000000003517 179.0
MMD2_k127_2630851_47 PFAM Patatin K07001 GO:0003674,GO:0003824,GO:0016787 - 0.000000000000000000000000000000000000000007564 164.0
MMD2_k127_2630851_48 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000009225 161.0
MMD2_k127_2630851_49 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.000000000000000000000000000000000008741 141.0
MMD2_k127_2630851_5 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 474.0
MMD2_k127_2630851_50 peroxiredoxin activity - - - 0.0000000000000000000000000000003138 128.0
MMD2_k127_2630851_51 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000002099 116.0
MMD2_k127_2630851_52 Belongs to the NUDIX hydrolase family - - - 0.000000000000000000004178 105.0
MMD2_k127_2630851_53 Peptidase M48 - - - 0.00000000000000000003822 106.0
MMD2_k127_2630851_54 transferase activity, transferring glycosyl groups - - - 0.0000000000000003056 90.0
MMD2_k127_2630851_55 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000008665 87.0
MMD2_k127_2630851_56 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000002731 86.0
MMD2_k127_2630851_57 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000001087 87.0
MMD2_k127_2630851_58 Acylphosphatase K01512 - 3.6.1.7 0.00000000000001489 82.0
MMD2_k127_2630851_59 regulatory protein, FmdB family - - - 0.00000000000002403 75.0
MMD2_k127_2630851_6 PFAM UMUC domain protein DNA-repair protein K02346,K03502 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006967 456.0
MMD2_k127_2630851_60 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000001919 70.0
MMD2_k127_2630851_61 anaphase-promoting complex binding - - - 0.000000000004224 81.0
MMD2_k127_2630851_62 Tetratricopeptide repeat - - - 0.000000000004719 77.0
MMD2_k127_2630851_63 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.00000000003411 73.0
MMD2_k127_2630851_64 - - - - 0.0000000003246 62.0
MMD2_k127_2630851_65 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000002576 62.0
MMD2_k127_2630851_66 TPR repeat - - - 0.000001413 61.0
MMD2_k127_2630851_67 - - - - 0.000003985 59.0
MMD2_k127_2630851_68 Periplasmic copper-binding protein (NosD) - - - 0.00001253 57.0
MMD2_k127_2630851_69 Glucose / Sorbosone dehydrogenase - - - 0.00003067 55.0
MMD2_k127_2630851_7 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 431.0
MMD2_k127_2630851_70 Belongs to the peptidase S8 family - - - 0.00005858 57.0
MMD2_k127_2630851_71 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.0003357 53.0
MMD2_k127_2630851_8 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 431.0
MMD2_k127_2630851_9 Penicillin-binding protein 2 K05515 GO:0000270,GO:0003674,GO:0003824,GO:0004180,GO:0004185,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006022,GO:0006023,GO:0006024,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0008238,GO:0008360,GO:0008658,GO:0009002,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0016787,GO:0017171,GO:0019538,GO:0022603,GO:0022604,GO:0030203,GO:0031224,GO:0031226,GO:0031406,GO:0033218,GO:0033293,GO:0034645,GO:0036094,GO:0042221,GO:0042493,GO:0042546,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044425,GO:0044459,GO:0044464,GO:0045229,GO:0046677,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0051128,GO:0065007,GO:0065008,GO:0070008,GO:0070011,GO:0070589,GO:0071554,GO:0071555,GO:0071704,GO:0071840,GO:0071944,GO:0071972,GO:0097159,GO:0140096,GO:1901135,GO:1901137,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 439.0
MMD2_k127_2636700_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 506.0
MMD2_k127_2636700_1 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 396.0
MMD2_k127_2636700_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003278 282.0
MMD2_k127_2636700_3 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000009809 200.0
MMD2_k127_2636700_4 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000001527 190.0
MMD2_k127_2636700_5 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000009638 154.0
MMD2_k127_2636700_6 ORF6N domain - - - 0.00000000000000000000000000000000000004608 147.0
MMD2_k127_2636700_7 Histidine kinase K13598 - 2.7.13.3 0.00000000000000000000000000000000000504 147.0
MMD2_k127_2755175_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 1.974e-196 623.0
MMD2_k127_2755175_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 435.0
MMD2_k127_2755175_10 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.0000000000000000000000001353 119.0
MMD2_k127_2755175_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000001342 93.0
MMD2_k127_2755175_12 PFAM CheW domain protein K03408 - - 0.0000000000003606 74.0
MMD2_k127_2755175_13 - - - - 0.00007463 45.0
MMD2_k127_2755175_2 Family 5 K02035,K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001972 302.0
MMD2_k127_2755175_3 spore germination K03298 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004424 259.0
MMD2_k127_2755175_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000007375 193.0
MMD2_k127_2755175_5 flavin adenine dinucleotide binding - - - 0.0000000000000000000000000000000000000002483 158.0
MMD2_k127_2755175_6 PFAM Uncharacterised ACR, COG1259 K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000003695 142.0
MMD2_k127_2755175_7 23S rRNA-intervening sequence protein - - - 0.000000000000000000000000000000000005561 140.0
MMD2_k127_2755175_8 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000181 119.0
MMD2_k127_2755175_9 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000001205 117.0
MMD2_k127_2788783_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 506.0
MMD2_k127_2788783_1 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 431.0
MMD2_k127_2788783_10 glycosyl hydrolase, BNR repeat-containing protein - - - 0.00000000000000000000002572 113.0
MMD2_k127_2788783_11 Thioredoxin-like - - - 0.00000000000000000000006104 114.0
MMD2_k127_2788783_12 Sortilin, neurotensin receptor 3, - - - 0.0000000000000000000001015 111.0
MMD2_k127_2788783_13 Cold shock protein K03704 - - 0.0000000000000000003889 88.0
MMD2_k127_2788783_15 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000001999 76.0
MMD2_k127_2788783_16 - - - - 0.000000000001839 70.0
MMD2_k127_2788783_17 Sortilin, neurotensin receptor 3, - - - 0.0000000001126 72.0
MMD2_k127_2788783_18 exo-alpha-(2->6)-sialidase activity - - - 0.000000002251 70.0
MMD2_k127_2788783_19 Kelch motif - - - 0.000000002592 69.0
MMD2_k127_2788783_2 Adenylate cyclase, family 3 (some proteins contain HAMP domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 410.0
MMD2_k127_2788783_20 Phosphodiester glycosidase K05996 - 3.4.17.18 0.0000000304 65.0
MMD2_k127_2788783_21 - - - - 0.0000009123 60.0
MMD2_k127_2788783_22 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.00002399 50.0
MMD2_k127_2788783_23 metallocarboxypeptidase activity - - - 0.00004178 55.0
MMD2_k127_2788783_24 ATP-independent chaperone mediated protein folding K07803 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0008270,GO:0016151,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050897 - 0.00006038 51.0
MMD2_k127_2788783_3 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007586 393.0
MMD2_k127_2788783_4 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000003254 215.0
MMD2_k127_2788783_5 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.000000000000000000000000000000000000000000000000000000007498 210.0
MMD2_k127_2788783_6 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000006673 124.0
MMD2_k127_2788783_7 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000008712 131.0
MMD2_k127_2788783_8 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000001141 127.0
MMD2_k127_2788783_9 Two component regulator propeller - - - 0.000000000000000000000000008706 124.0
MMD2_k127_2824840_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009198 527.0
MMD2_k127_2824840_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 490.0
MMD2_k127_2824840_10 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000000102 75.0
MMD2_k127_2824840_11 nitroreductase K19286 - 1.5.1.39 0.000000001121 63.0
MMD2_k127_2824840_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001021 237.0
MMD2_k127_2824840_3 PFAM KWG Leptospira - - - 0.000000000000000000000000000000000000000000000000000000000000001834 233.0
MMD2_k127_2824840_4 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000005077 186.0
MMD2_k127_2824840_5 NIL - - - 0.000000000000000000000000000000001041 147.0
MMD2_k127_2824840_6 Glutaredoxin - - - 0.000000000000000000000000004857 112.0
MMD2_k127_2824840_7 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain - - - 0.000000000000000000000002558 111.0
MMD2_k127_2824840_9 PFAM ApbE family - - - 0.000000000000000008422 89.0
MMD2_k127_2832079_0 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003384 278.0
MMD2_k127_2832079_1 toxin-antitoxin pair type II binding - - - 0.000000000000000009307 87.0
MMD2_k127_2832079_2 Tetratricopeptide repeat - - - 0.00000000000000004633 92.0
MMD2_k127_2837361_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003272 615.0
MMD2_k127_2837361_1 Bacterial regulatory protein, Fis family K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 355.0
MMD2_k127_2837361_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005863 276.0
MMD2_k127_2837361_3 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001499 252.0
MMD2_k127_2837361_4 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000002081 232.0
MMD2_k127_2837361_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000005774 187.0
MMD2_k127_2837361_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000003952 169.0
MMD2_k127_2837361_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000386 126.0
MMD2_k127_2837361_8 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.000000000000000000000000239 111.0
MMD2_k127_2837361_9 cellulose binding K00505 - 1.14.18.1 0.0000000005782 72.0
MMD2_k127_2866901_0 Ribosomal protein S1 K02945,K03527,K12132 GO:0005575,GO:0005576,GO:0018995,GO:0020003,GO:0030430,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0065010 1.17.7.4,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 488.0
MMD2_k127_2866901_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 329.0
MMD2_k127_2866901_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000004374 233.0
MMD2_k127_2866901_3 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000819 233.0
MMD2_k127_2866901_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000007945 153.0
MMD2_k127_2866901_5 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000003752 66.0
MMD2_k127_2866901_6 guanyl-nucleotide exchange factor activity - - - 0.000002091 62.0
MMD2_k127_2889170_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.707e-261 824.0
MMD2_k127_2889170_1 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000907 349.0
MMD2_k127_2889170_10 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000006957 170.0
MMD2_k127_2889170_11 radical SAM domain protein - - - 0.000000000000000000000000000000000000000002615 169.0
MMD2_k127_2889170_12 Peptidase M14, carboxypeptidase A K05996 - 3.4.17.18 0.000000000000000000000000000000000000002786 168.0
MMD2_k127_2889170_13 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000004578 124.0
MMD2_k127_2889170_14 Psort location OuterMembrane, score - - - 0.00000000000000000009152 104.0
MMD2_k127_2889170_15 Mitochondrial small ribosomal subunit Rsm22 - - - 0.0000000000000000002554 100.0
MMD2_k127_2889170_16 3'-5' exonuclease activity K03547 - - 0.0000000000000003282 92.0
MMD2_k127_2889170_17 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000001911 74.0
MMD2_k127_2889170_18 AAA domain - - - 0.0000000001728 75.0
MMD2_k127_2889170_19 Domain of unknown function (DUF1844) - - - 0.0000000001983 65.0
MMD2_k127_2889170_2 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005516 248.0
MMD2_k127_2889170_21 bacterial-type flagellum-dependent cell motility - - - 0.000003825 58.0
MMD2_k127_2889170_22 AAA domain - - - 0.000004718 60.0
MMD2_k127_2889170_23 - - - - 0.00001214 59.0
MMD2_k127_2889170_24 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00003046 57.0
MMD2_k127_2889170_25 peptidase activity, acting on L-amino acid peptides K07752 - 3.4.17.22 0.000108 55.0
MMD2_k127_2889170_3 Protein of unknown function (DUF2723) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004877 251.0
MMD2_k127_2889170_4 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000007396 244.0
MMD2_k127_2889170_5 RNA-binding PUA-like domain of methyltransferase RsmF - - - 0.00000000000000000000000000000000000000000000000000000000000000001112 241.0
MMD2_k127_2889170_6 Protein of unknown function (DUF401) K09133 - - 0.000000000000000000000000000000000000000000000000000001408 207.0
MMD2_k127_2889170_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000005051 202.0
MMD2_k127_2889170_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000002673 186.0
MMD2_k127_2889170_9 - - - - 0.00000000000000000000000000000000000000000000007101 179.0
MMD2_k127_2951984_0 Dehydratase family K01687 - 4.2.1.9 3.573e-204 649.0
MMD2_k127_2951984_1 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 3.867e-198 650.0
MMD2_k127_2951984_10 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 410.0
MMD2_k127_2951984_11 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002527 399.0
MMD2_k127_2951984_12 PFAM amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 378.0
MMD2_k127_2951984_13 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 377.0
MMD2_k127_2951984_14 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 355.0
MMD2_k127_2951984_15 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 353.0
MMD2_k127_2951984_16 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 343.0
MMD2_k127_2951984_17 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 346.0
MMD2_k127_2951984_18 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009436 339.0
MMD2_k127_2951984_19 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005612 325.0
MMD2_k127_2951984_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 560.0
MMD2_k127_2951984_20 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 304.0
MMD2_k127_2951984_21 Acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000111 288.0
MMD2_k127_2951984_22 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000464 289.0
MMD2_k127_2951984_23 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000002371 259.0
MMD2_k127_2951984_24 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000006345 240.0
MMD2_k127_2951984_25 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000001573 224.0
MMD2_k127_2951984_26 Transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000006617 241.0
MMD2_k127_2951984_27 40-residue YVTN family beta-propeller repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000005113 216.0
MMD2_k127_2951984_28 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000001602 230.0
MMD2_k127_2951984_29 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K01663,K02501 - - 0.000000000000000000000000000000000000000000000000000000005546 206.0
MMD2_k127_2951984_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 532.0
MMD2_k127_2951984_30 Pyruvate formate lyase-like K00656 - 2.3.1.54 0.0000000000000000000000000000000000000000000000000001438 187.0
MMD2_k127_2951984_31 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000003354 199.0
MMD2_k127_2951984_32 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.000000000000000000000000000000000000000000000005676 186.0
MMD2_k127_2951984_33 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000001269 183.0
MMD2_k127_2951984_34 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000008208 168.0
MMD2_k127_2951984_35 Galactose oxidase, central domain - - - 0.0000000000000000000000003164 119.0
MMD2_k127_2951984_36 CAAX protease self-immunity K07052 - - 0.0000000000000000002201 98.0
MMD2_k127_2951984_37 Domain of unknown function (DUF4388) - - - 0.0000000000000000002452 98.0
MMD2_k127_2951984_38 Chaperone - - - 0.000000000000000003561 94.0
MMD2_k127_2951984_39 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000001114 90.0
MMD2_k127_2951984_4 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 482.0
MMD2_k127_2951984_40 belongs to the glycosyl hydrolase 13 family - - - 0.00000000000001279 87.0
MMD2_k127_2951984_41 Spi protease inhibitor - - - 0.00000000000002456 87.0
MMD2_k127_2951984_42 ACT domain K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.00000000000003794 74.0
MMD2_k127_2951984_43 domain protein K14194 - - 0.0000000004211 73.0
MMD2_k127_2951984_44 polysaccharide catabolic process K01179 - 3.2.1.4 0.000001825 61.0
MMD2_k127_2951984_45 guanyl-nucleotide exchange factor activity - - - 0.000008507 58.0
MMD2_k127_2951984_5 Phosphoribosyl-AMP cyclohydrolase K01496,K01497,K01814,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0004635,GO:0004636,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016462,GO:0016787,GO:0016810,GO:0016814,GO:0016817,GO:0016818,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.5.4.25,3.6.1.31,5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 478.0
MMD2_k127_2951984_6 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 430.0
MMD2_k127_2951984_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 431.0
MMD2_k127_2951984_8 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 426.0
MMD2_k127_2951984_9 PFAM DAHP synthetase I K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 410.0
MMD2_k127_2995682_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 429.0
MMD2_k127_2995682_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 320.0
MMD2_k127_2995682_2 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 304.0
MMD2_k127_2995682_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000006835 153.0
MMD2_k127_2995682_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000001088 117.0
MMD2_k127_3024065_0 Amino acid polyamine organocation transporter, APC superfamily K03294 - - 9.991e-229 718.0
MMD2_k127_3024065_1 PFAM NADH Ubiquinone plastoquinone (complex I) K12137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 490.0
MMD2_k127_3024065_10 hydrogenase maturation protease HycI K08315 - 3.4.23.51 0.00000000000000000000000000002464 123.0
MMD2_k127_3024065_11 domain protein K03499 - - 0.00000000000000000000000000002692 121.0
MMD2_k127_3024065_12 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000006232 121.0
MMD2_k127_3024065_13 PFAM Uncharacterised protein family (UPF0164) - - - 0.00000000000000000000000002355 119.0
MMD2_k127_3024065_14 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000001327 106.0
MMD2_k127_3024065_15 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14091 - - 0.000000000000000000002264 109.0
MMD2_k127_3024065_18 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.00000000001427 72.0
MMD2_k127_3024065_19 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.000000005835 61.0
MMD2_k127_3024065_2 PFAM NADH Ubiquinone plastoquinone (complex I) K00341,K05568,K12139,K14086 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008059 479.0
MMD2_k127_3024065_20 Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000006989 66.0
MMD2_k127_3024065_21 TrkA-N domain K03499 - - 0.0000005619 53.0
MMD2_k127_3024065_3 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 477.0
MMD2_k127_3024065_4 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 366.0
MMD2_k127_3024065_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 303.0
MMD2_k127_3024065_6 PFAM Kelch repeat type 1 K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005902 277.0
MMD2_k127_3024065_7 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.00000000000000000000000000000000000000000000000000000000000000000004806 233.0
MMD2_k127_3024065_8 AMP binding - - - 0.00000000000000000000000000000000000000000000000000001962 197.0
MMD2_k127_3024065_9 - - - - 0.0000000000000000000000000000000000000000001013 163.0
MMD2_k127_3053942_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 4.359e-244 763.0
MMD2_k127_305660_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1234.0
MMD2_k127_305660_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 589.0
MMD2_k127_305660_10 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000006021 89.0
MMD2_k127_305660_12 Belongs to the UPF0434 family K09791 - - 0.0000000000000256 74.0
MMD2_k127_305660_13 Peptidase family C25 - - - 0.00000000000007598 78.0
MMD2_k127_305660_14 FlgD Ig-like domain K14194,K19668 - 3.2.1.91 0.00000002891 68.0
MMD2_k127_305660_2 transferase activity, transferring glycosyl groups K00694,K00786 - 2.4.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 402.0
MMD2_k127_305660_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 337.0
MMD2_k127_305660_4 Propeptide_C25 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 363.0
MMD2_k127_305660_5 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008075 330.0
MMD2_k127_305660_6 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 319.0
MMD2_k127_305660_7 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 268.0
MMD2_k127_305660_8 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000005207 184.0
MMD2_k127_305660_9 Kelch motif - - - 0.00000000000000000000000000000000003661 156.0
MMD2_k127_3140347_0 Alpha-2-Macroglobulin K06894 - - 0.0 1156.0
MMD2_k127_3140347_1 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007618 517.0
MMD2_k127_3140347_10 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 316.0
MMD2_k127_3140347_11 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 311.0
MMD2_k127_3140347_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 287.0
MMD2_k127_3140347_13 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004724 278.0
MMD2_k127_3140347_14 Trypsin K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000002065 278.0
MMD2_k127_3140347_15 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000004108 258.0
MMD2_k127_3140347_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001622 270.0
MMD2_k127_3140347_17 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001389 251.0
MMD2_k127_3140347_18 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000004171 248.0
MMD2_k127_3140347_19 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000003024 237.0
MMD2_k127_3140347_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 498.0
MMD2_k127_3140347_20 Subtilase family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000002906 238.0
MMD2_k127_3140347_21 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000004209 231.0
MMD2_k127_3140347_22 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000003191 219.0
MMD2_k127_3140347_23 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000003309 218.0
MMD2_k127_3140347_24 Phosphorylase superfamily K00772,K03784 - 2.4.2.1,2.4.2.28 0.0000000000000000000000000000000000000000000000000000132 198.0
MMD2_k127_3140347_25 beta-N-acetylglucosaminidase K01197 - 3.2.1.35 0.00000000000000000000000000000000000000000000000002621 189.0
MMD2_k127_3140347_26 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000001036 184.0
MMD2_k127_3140347_27 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000002527 181.0
MMD2_k127_3140347_28 Domain of unknown function (DUF366) K09139 - - 0.0000000000000000000000000000000000000000000006889 171.0
MMD2_k127_3140347_29 TIGR00255 family - - - 0.0000000000000000000000000000000000000000000009306 176.0
MMD2_k127_3140347_3 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 429.0
MMD2_k127_3140347_30 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000007441 181.0
MMD2_k127_3140347_31 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000003437 162.0
MMD2_k127_3140347_32 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000005839 168.0
MMD2_k127_3140347_33 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000000002045 108.0
MMD2_k127_3140347_34 LAGLIDADG-like domain - - - 0.0000000000000000000000368 111.0
MMD2_k127_3140347_35 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000007112 97.0
MMD2_k127_3140347_36 rubredoxin - - - 0.00000000000000000664 86.0
MMD2_k127_3140347_37 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000004877 66.0
MMD2_k127_3140347_38 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02768,K02806 - 2.7.1.202 0.0000000000171 70.0
MMD2_k127_3140347_39 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000003109 62.0
MMD2_k127_3140347_4 Permease K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 411.0
MMD2_k127_3140347_40 protein kinase activity - - - 0.0000088 59.0
MMD2_k127_3140347_41 VanZ like family - - - 0.00003851 51.0
MMD2_k127_3140347_5 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 396.0
MMD2_k127_3140347_6 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 373.0
MMD2_k127_3140347_7 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 366.0
MMD2_k127_3140347_8 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009692 347.0
MMD2_k127_3140347_9 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008166 340.0
MMD2_k127_3148594_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 370.0
MMD2_k127_3148594_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 316.0
MMD2_k127_3148594_10 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000002183 173.0
MMD2_k127_3148594_11 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000000000000000001103 153.0
MMD2_k127_3148594_12 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000317 172.0
MMD2_k127_3148594_13 nucleic acid binding K01174 - 3.1.31.1 0.0000000000000000000000000000000000000006157 158.0
MMD2_k127_3148594_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.00000000000000000000000000000000001952 139.0
MMD2_k127_3148594_15 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000792 139.0
MMD2_k127_3148594_16 Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000001268 144.0
MMD2_k127_3148594_17 Tetratricopeptide repeat - - - 0.00000000000000000000000000001078 127.0
MMD2_k127_3148594_18 - - - - 0.00000000000000000000000000001524 129.0
MMD2_k127_3148594_19 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000002164 92.0
MMD2_k127_3148594_2 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 331.0
MMD2_k127_3148594_20 OmpA family - - - 0.00000000000000004041 95.0
MMD2_k127_3148594_21 Capsule synthesis protein K07282 - - 0.0000000000000003616 90.0
MMD2_k127_3148594_22 Transcriptional regulator, TraR DksA family K06204 - - 0.0000000000000008676 81.0
MMD2_k127_3148594_23 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019904,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701 - 0.000000000000008399 85.0
MMD2_k127_3148594_24 PFAM FecR protein K17713 - - 0.000001944 59.0
MMD2_k127_3148594_25 Acid phosphatase homologues K19302 - 3.6.1.27 0.00002729 53.0
MMD2_k127_3148594_3 RHS Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000001041 268.0
MMD2_k127_3148594_4 Abc transporter K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000000009691 239.0
MMD2_k127_3148594_5 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000000002858 232.0
MMD2_k127_3148594_6 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000838 248.0
MMD2_k127_3148594_7 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000002345 188.0
MMD2_k127_3148594_8 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000002373 181.0
MMD2_k127_3148594_9 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000007175 173.0
MMD2_k127_3189316_0 ABC-type antimicrobial peptide transport system, ATPase component K02003,K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001441 268.0
MMD2_k127_3189316_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000324 235.0
MMD2_k127_3189316_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000006766 166.0
MMD2_k127_3189316_3 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000001484 154.0
MMD2_k127_3189316_4 - - - - 0.000000000000000000000000000476 127.0
MMD2_k127_3189316_5 Belongs to the ompA family - - - 0.000000000000000000000001104 120.0
MMD2_k127_3189316_6 PBS lyase HEAT-like repeat - - - 0.0000000000001752 82.0
MMD2_k127_3189316_7 Periplasmic copper-binding protein (NosD) - - - 0.00000000192 71.0
MMD2_k127_3189316_8 cellulose binding - - - 0.000000007645 69.0
MMD2_k127_3247914_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K11928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009896 293.0
MMD2_k127_3247914_1 cellulase activity K06882 - - 0.000000000000000000000000000000000000000000000000000000000000000000005077 242.0
MMD2_k127_3247914_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000004715 212.0
MMD2_k127_3247914_3 - - - - 0.00000000000000000000000000000000001062 149.0
MMD2_k127_3247914_4 amino acid K16261 GO:0000322,GO:0000323,GO:0000324,GO:0000329,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0005783,GO:0005789,GO:0005886,GO:0005887,GO:0008150,GO:0012505,GO:0016020,GO:0016021,GO:0031090,GO:0031224,GO:0031226,GO:0031984,GO:0032879,GO:0034762,GO:0034764,GO:0034765,GO:0034767,GO:0042175,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043269,GO:0043270,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044437,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050789,GO:0051049,GO:0051050,GO:0065007,GO:0071944,GO:0098588,GO:0098805,GO:0098827,GO:0098852,GO:1902267,GO:1902269,GO:1902272,GO:1902274,GO:1904062,GO:1904064,GO:2001023,GO:2001025 - 0.000176 44.0
MMD2_k127_3318124_0 Tricorn protease homolog K08676 - - 0.0 1062.0
MMD2_k127_3318124_1 Urocanase C-terminal domain K01712 - 4.2.1.49 3.568e-259 810.0
MMD2_k127_3318124_10 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
MMD2_k127_3318124_11 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000001384 190.0
MMD2_k127_3318124_12 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000003926 101.0
MMD2_k127_3318124_13 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000001332 96.0
MMD2_k127_3318124_14 rRNA binding K02909 - - 0.000000000000000001217 100.0
MMD2_k127_3318124_15 cellulose binding - - - 0.00000000000004876 87.0
MMD2_k127_3318124_16 extracellular matrix structural constituent - - - 0.0000000000001284 84.0
MMD2_k127_3318124_17 FlgD Ig-like domain K13669 - - 0.0000000000004782 83.0
MMD2_k127_3318124_18 Glycosyl hydrolase family 70 K01142,K01176 - 3.1.11.2,3.2.1.1 0.00000003891 67.0
MMD2_k127_3318124_19 GGDEF domain K03413 - - 0.00001372 55.0
MMD2_k127_3318124_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002458 532.0
MMD2_k127_3318124_3 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 556.0
MMD2_k127_3318124_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004623 447.0
MMD2_k127_3318124_5 translation release factor activity K02836 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0016149,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 367.0
MMD2_k127_3318124_6 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 356.0
MMD2_k127_3318124_7 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 321.0
MMD2_k127_3318124_8 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 334.0
MMD2_k127_3318124_9 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002764 284.0
MMD2_k127_3327816_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 3.54e-321 1002.0
MMD2_k127_3327816_1 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 9.784e-313 993.0
MMD2_k127_3327816_10 Roadblock/LC7 domain - - - 0.00000000000000000000000000000000001501 141.0
MMD2_k127_3327816_11 AAA domain K07133 - - 0.000000000000000000000000000003382 136.0
MMD2_k127_3327816_12 - - - - 0.000000000000000000000002794 109.0
MMD2_k127_3327816_13 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000009434 71.0
MMD2_k127_3327816_14 peptidase activity, acting on L-amino acid peptides K01187,K01448,K07752 - 3.2.1.20,3.4.17.22,3.5.1.28 0.0000000002085 73.0
MMD2_k127_3327816_15 extracellular matrix structural constituent - - - 0.0000000005575 69.0
MMD2_k127_3327816_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 2.378e-263 830.0
MMD2_k127_3327816_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 2.04e-228 741.0
MMD2_k127_3327816_4 TonB dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 388.0
MMD2_k127_3327816_5 serine-type peptidase activity K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 349.0
MMD2_k127_3327816_6 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 344.0
MMD2_k127_3327816_7 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006652 273.0
MMD2_k127_3327816_8 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001738 244.0
MMD2_k127_3327816_9 PFAM GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000000000717 192.0
MMD2_k127_3400252_0 Diguanylate cyclase - - - 0.000000000000000000000000000000004893 134.0
MMD2_k127_3400252_1 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000005411 126.0
MMD2_k127_3400252_2 40-residue YVTN family beta-propeller repeat - - - 0.0000000249 68.0
MMD2_k127_3442165_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 431.0
MMD2_k127_3442165_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 385.0
MMD2_k127_3442165_10 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000005813 108.0
MMD2_k127_3442165_11 Hep Hag repeat protein - - - 0.000000000000000000000002726 120.0
MMD2_k127_3442165_12 - - - - 0.0000000000000002919 84.0
MMD2_k127_3442165_13 pfam yhs - - - 0.00000000000005738 73.0
MMD2_k127_3442165_14 TonB-dependent receptor - - - 0.000000000003689 79.0
MMD2_k127_3442165_15 bacterial-type flagellum-dependent cell motility - - - 0.0001347 53.0
MMD2_k127_3442165_2 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 364.0
MMD2_k127_3442165_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 361.0
MMD2_k127_3442165_4 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 330.0
MMD2_k127_3442165_5 ABC transporter, ATP-binding protein K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 289.0
MMD2_k127_3442165_6 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000000001257 241.0
MMD2_k127_3442165_7 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000000000000000000000000000000000008405 212.0
MMD2_k127_3442165_8 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000001664 223.0
MMD2_k127_3442165_9 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000001407 158.0
MMD2_k127_3484321_0 UDP binding domain K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 503.0
MMD2_k127_3484321_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 396.0
MMD2_k127_3484321_10 Belongs to the TtcA family K14058 - - 0.000000000000000000000000000000000002948 149.0
MMD2_k127_3484321_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000006354 126.0
MMD2_k127_3484321_12 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000001791 118.0
MMD2_k127_3484321_13 Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000008757 101.0
MMD2_k127_3484321_14 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000191 91.0
MMD2_k127_3484321_15 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.000000000001165 81.0
MMD2_k127_3484321_16 extracellular matrix structural constituent - - - 0.0000000001806 72.0
MMD2_k127_3484321_17 sequence-specific DNA binding - - - 0.000000000654 62.0
MMD2_k127_3484321_18 Anti-sigma factor antagonist K02066,K04749 - - 0.0000002285 57.0
MMD2_k127_3484321_2 NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 385.0
MMD2_k127_3484321_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 306.0
MMD2_k127_3484321_4 extracellular solute-binding protein, family 5 K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004588 281.0
MMD2_k127_3484321_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001578 265.0
MMD2_k127_3484321_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000002629 239.0
MMD2_k127_3484321_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000001128 234.0
MMD2_k127_3484321_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000002176 213.0
MMD2_k127_3484321_9 Competence-damaged protein K03743 - 3.5.1.42 0.00000000000000000000000000000000000002139 151.0
MMD2_k127_356206_0 AAA ATPase domain K01768 - 4.6.1.1 1.393e-244 801.0
MMD2_k127_356206_1 cysteine-tRNA ligase activity K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 464.0
MMD2_k127_356206_2 metallopeptidase activity K06974 - - 0.000000000000000000000000000000000000000000001393 181.0
MMD2_k127_356206_3 Protease prsW family - - - 0.0000000000000000000000000000000000000001485 169.0
MMD2_k127_356206_4 Belongs to the peptidase S51 family K13282 - 3.4.15.6 0.0000000000000000006021 98.0
MMD2_k127_357829_0 intracellular signal transduction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 365.0
MMD2_k127_3586268_0 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 390.0
MMD2_k127_3586268_1 Argininosuccinate lyase C-terminal K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 363.0
MMD2_k127_3586268_10 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000002607 246.0
MMD2_k127_3586268_11 leucine binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001558 236.0
MMD2_k127_3586268_12 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000002108 237.0
MMD2_k127_3586268_13 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000001896 207.0
MMD2_k127_3586268_15 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000005114 185.0
MMD2_k127_3586268_16 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.000000000000000000000000000000000006944 156.0
MMD2_k127_3586268_17 2-phosphosulfolactate phosphatase activity K05979 - 3.1.3.71 0.00000000000000000000000000000000004114 146.0
MMD2_k127_3586268_18 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000001299 140.0
MMD2_k127_3586268_19 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.0000000000000000000000000001623 132.0
MMD2_k127_3586268_2 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 342.0
MMD2_k127_3586268_20 Regulates arginine biosynthesis genes K03402 - - 0.000000000000000000000000000638 118.0
MMD2_k127_3586268_21 PKD domain - - - 0.000000000000000000000000991 116.0
MMD2_k127_3586268_23 helix_turn_helix, mercury resistance K19591,K22491 - - 0.000000000000000000003204 97.0
MMD2_k127_3586268_24 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.0000000000000000002494 104.0
MMD2_k127_3586268_25 LysM domain - - - 0.0000000000000000003219 99.0
MMD2_k127_3586268_26 serine threonine protein kinase - - - 0.00000006767 67.0
MMD2_k127_3586268_27 COG NOG18433 non supervised orthologous group - - - 0.00008661 49.0
MMD2_k127_3586268_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 332.0
MMD2_k127_3586268_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
MMD2_k127_3586268_5 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006565 305.0
MMD2_k127_3586268_6 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009475 310.0
MMD2_k127_3586268_7 transmembrane transport K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 296.0
MMD2_k127_3586268_8 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009089 284.0
MMD2_k127_3586268_9 Protein of unknown function (DUF2723) K16928 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003223 298.0
MMD2_k127_366175_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 1.326e-300 942.0
MMD2_k127_366175_1 ATP-dependent peptidase activity K01338,K04076,K04770 - 3.4.21.53 9.749e-233 744.0
MMD2_k127_366175_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000007375 190.0
MMD2_k127_366175_11 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000001152 151.0
MMD2_k127_366175_12 Sigma-70, region 4 K03088 - - 0.00000000000000000003594 97.0
MMD2_k127_366175_13 GIY-YIG catalytic domain protein K07461 - - 0.000000000000000005534 86.0
MMD2_k127_366175_14 Pyridoxamine 5'-phosphate oxidase - - - 0.00000000049 66.0
MMD2_k127_366175_15 DNA polymerase III K02340 - 2.7.7.7 0.00000007537 63.0
MMD2_k127_366175_16 Lamin Tail Domain - - - 0.0000002824 63.0
MMD2_k127_366175_17 - - - - 0.0000006648 61.0
MMD2_k127_366175_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 447.0
MMD2_k127_366175_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 424.0
MMD2_k127_366175_4 Transcriptional regulator containing GAF AAA-type ATPase and DNA binding domains K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 413.0
MMD2_k127_366175_5 Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 395.0
MMD2_k127_366175_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
MMD2_k127_366175_7 metallophosphoesterase K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001407 255.0
MMD2_k127_366175_8 TGS domain K06944 - - 0.0000000000000000000000000000000000000000000000000000002069 203.0
MMD2_k127_366175_9 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000000000000000000000000000000007631 196.0
MMD2_k127_3740709_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 329.0
MMD2_k127_3740709_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000002497 269.0
MMD2_k127_3740709_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02236,K02278,K02506,K02654,K10966 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000002545 212.0
MMD2_k127_3740709_3 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000006482 197.0
MMD2_k127_3740709_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000001929 82.0
MMD2_k127_3740709_5 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000001752 76.0
MMD2_k127_3740709_6 PFAM Transposase IS200 like K07491 - - 0.0000000002431 68.0
MMD2_k127_3740709_7 peptidyl-tyrosine sulfation - - - 0.0000002039 63.0
MMD2_k127_3740709_8 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K16363 - 3.5.1.108,4.2.1.59 0.000002884 50.0
MMD2_k127_3798015_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.923e-236 749.0
MMD2_k127_3798015_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 581.0
MMD2_k127_3798015_10 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 340.0
MMD2_k127_3798015_11 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001449 254.0
MMD2_k127_3798015_12 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000009026 199.0
MMD2_k127_3798015_13 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000000000000000000000000000000000002349 160.0
MMD2_k127_3798015_14 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000006739 143.0
MMD2_k127_3798015_15 ligase activity, forming carbon-carbon bonds K00627,K01571,K02160 - 2.3.1.12,4.1.1.3 0.0000000000000000000000000000000001684 143.0
MMD2_k127_3798015_16 Bacterial lipid A biosynthesis acyltransferase K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.265 0.00000000000000000000000001263 120.0
MMD2_k127_3798015_17 PTS HPr component phosphorylation site K11189 - - 0.000000000000000000002179 95.0
MMD2_k127_3798015_18 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000003204 97.0
MMD2_k127_3798015_19 Tetratricopeptide repeat - - - 0.000000000000000000003264 104.0
MMD2_k127_3798015_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 590.0
MMD2_k127_3798015_20 PTS system sorbose subfamily IIB component K19507 - - 0.000000000000000000003494 99.0
MMD2_k127_3798015_21 Transmembrane secretion effector - - - 0.0000000000000000004181 101.0
MMD2_k127_3798015_22 PTS system mannose/fructose/sorbose family IID component K02796 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0008982,GO:0009401,GO:0015144,GO:0015145,GO:0015149,GO:0015578,GO:0015749,GO:0015761,GO:0016020,GO:0016021,GO:0016740,GO:0016772,GO:0016773,GO:0022804,GO:0022857,GO:0022870,GO:0031224,GO:0031226,GO:0034219,GO:0044425,GO:0044459,GO:0044464,GO:0046323,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098657,GO:0098704,GO:0098708,GO:0098739,GO:1904659 - 0.00000000000000000453 97.0
MMD2_k127_3798015_23 Domain of unknown function (DUF4837) - - - 0.0000000000000001137 93.0
MMD2_k127_3798015_24 TIGRFAM phenazine biosynthesis protein PhzF family - - - 0.0000000000001049 83.0
MMD2_k127_3798015_25 Tetratricopeptide repeat - - - 0.00000000002919 76.0
MMD2_k127_3798015_26 PTS system sorbose-specific iic component K19508 - - 0.00000001079 64.0
MMD2_k127_3798015_27 COG4771 Outer membrane receptor for ferrienterochelin and colicins K02014,K16089 - - 0.000001911 61.0
MMD2_k127_3798015_3 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 474.0
MMD2_k127_3798015_4 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 452.0
MMD2_k127_3798015_5 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008497 451.0
MMD2_k127_3798015_6 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 420.0
MMD2_k127_3798015_7 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 390.0
MMD2_k127_3798015_8 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 380.0
MMD2_k127_3798015_9 Glycosyl transferase 4-like domain K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 337.0
MMD2_k127_3807294_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1147.0
MMD2_k127_3807294_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.035e-204 668.0
MMD2_k127_3807294_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 461.0
MMD2_k127_3807294_3 Belongs to the acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006479 368.0
MMD2_k127_3807294_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 358.0
MMD2_k127_3807294_5 phosphate butyryltransferase K00634 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747,GO:0050182 2.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000007486 267.0
MMD2_k127_3807294_6 polysaccharide biosynthetic process - - - 0.000001963 51.0
MMD2_k127_3807294_7 Histidine kinase K02482 - 2.7.13.3 0.000003687 59.0
MMD2_k127_3821934_0 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004837 430.0
MMD2_k127_3821934_1 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 388.0
MMD2_k127_3821934_10 (Rhomboid) family - - - 0.0000000000000000000000000000000000000000104 171.0
MMD2_k127_3821934_11 Peptidase, M23 K21471 - - 0.0000000000000000000000000000000000000126 167.0
MMD2_k127_3821934_12 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.000000000000000000000000002305 122.0
MMD2_k127_3821934_13 methionine synthase K00548 - 2.1.1.13 0.0000000000000004933 91.0
MMD2_k127_3821934_14 protein secretion K09800 - - 0.00000000171 72.0
MMD2_k127_3821934_15 Endonuclease I - - - 0.0000001478 65.0
MMD2_k127_3821934_16 Fibronectin type 3 domain - - - 0.00002072 58.0
MMD2_k127_3821934_17 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.0002677 46.0
MMD2_k127_3821934_2 Ser Thr phosphatase family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 312.0
MMD2_k127_3821934_3 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005736 282.0
MMD2_k127_3821934_4 cell division ATP-binding protein FtsE K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.0000000000000000000000000000000000000000000000000000000000000000000003787 244.0
MMD2_k127_3821934_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000001162 230.0
MMD2_k127_3821934_6 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000000000000000000000000000926 251.0
MMD2_k127_3821934_7 Serine protease family S08A. Source PGD - - - 0.00000000000000000000000000000000000000000000000000000000001819 235.0
MMD2_k127_3821934_8 carbohydrate transport - - - 0.000000000000000000000000000000000000000000000000000000009677 204.0
MMD2_k127_3821934_9 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000000000000000002399 206.0
MMD2_k127_3842010_0 ABC transporter transmembrane region K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 595.0
MMD2_k127_3842010_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004659 582.0
MMD2_k127_3842010_10 - - - - 0.000000000000000000000000000000000000246 145.0
MMD2_k127_3842010_11 Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000224 134.0
MMD2_k127_3842010_12 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000009045 120.0
MMD2_k127_3842010_13 HAD-hyrolase-like K07025 - - 0.0000000000000000000000008342 115.0
MMD2_k127_3842010_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000003958 107.0
MMD2_k127_3842010_15 C4-type zinc ribbon domain K07164 - - 0.0000000000005132 73.0
MMD2_k127_3842010_16 TRANSCRIPTIONal - - - 0.0000000001818 70.0
MMD2_k127_3842010_17 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000004047 66.0
MMD2_k127_3842010_2 Psort location Cytoplasmic, score K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002117 482.0
MMD2_k127_3842010_3 arginyl-tRNA aminoacylation K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 421.0
MMD2_k127_3842010_4 ABC transporter transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 417.0
MMD2_k127_3842010_5 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 335.0
MMD2_k127_3842010_6 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007808 310.0
MMD2_k127_3842010_7 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000142 223.0
MMD2_k127_3842010_8 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000003937 214.0
MMD2_k127_3842010_9 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000001611 185.0
MMD2_k127_3844707_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.273e-280 889.0
MMD2_k127_3844707_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.776e-210 665.0
MMD2_k127_3844707_10 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000009781 239.0
MMD2_k127_3844707_11 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000188 241.0
MMD2_k127_3844707_12 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000006257 212.0
MMD2_k127_3844707_13 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000008172 175.0
MMD2_k127_3844707_14 Galactose oxidase, central domain - - - 0.00000000000000000000000000000000000000000001736 177.0
MMD2_k127_3844707_15 Kelch motif - - - 0.000000000000000000000000000000000002623 154.0
MMD2_k127_3844707_16 Kelch motif - - - 0.000000000000000000000000000000000009537 158.0
MMD2_k127_3844707_17 extracellular matrix structural constituent - - - 0.0000000000000000000000000000000001577 154.0
MMD2_k127_3844707_18 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000003319 132.0
MMD2_k127_3844707_19 Tetratricopeptide repeat - - - 0.0000000000000000000000001849 122.0
MMD2_k127_3844707_2 Myo-inositol-1-phosphate synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008659 585.0
MMD2_k127_3844707_20 Tetratricopeptide repeat - - - 0.0000000000000000000007214 111.0
MMD2_k127_3844707_21 Tetratricopeptide repeats - - - 0.00000000000003215 86.0
MMD2_k127_3844707_22 SPTR Peptidase S8 and S53 subtilisin kexin sedolisin K14645 - - 0.000000000004351 80.0
MMD2_k127_3844707_23 Lipopolysaccharide-assembly, LptC-related - - - 0.0000000000437 71.0
MMD2_k127_3844707_24 Magnesium chelatase, subunit ChlI K03404,K03405 - 6.6.1.1 0.00000002593 66.0
MMD2_k127_3844707_25 LVIVD repeat K01179 - 3.2.1.4 0.00000002957 68.0
MMD2_k127_3844707_26 cellulose binding - - - 0.0000002728 64.0
MMD2_k127_3844707_27 Kdo2-lipid A biosynthetic process - - - 0.00006152 53.0
MMD2_k127_3844707_28 Tetratricopeptide repeat - - - 0.0004587 53.0
MMD2_k127_3844707_29 Tetratricopeptide repeat - - - 0.0005536 46.0
MMD2_k127_3844707_3 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 469.0
MMD2_k127_3844707_30 OstA-like protein - - - 0.000807 51.0
MMD2_k127_3844707_4 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K07713 GO:0000156,GO:0000160,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0023052,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035556,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0060089,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 458.0
MMD2_k127_3844707_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 353.0
MMD2_k127_3844707_6 von Willebrand factor type A domain K03404 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 346.0
MMD2_k127_3844707_7 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008594 332.0
MMD2_k127_3844707_8 lipopolysaccharide transport protein B ATP-binding component of ABC superfamily K01990,K06861 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015221,GO:0015399,GO:0015405,GO:0015437,GO:0015920,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0032991,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043190,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1901264,GO:1901505,GO:1902494,GO:1902495,GO:1904949,GO:1990351 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000636 283.0
MMD2_k127_3844707_9 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003547 272.0
MMD2_k127_3863752_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 567.0
MMD2_k127_3863752_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 550.0
MMD2_k127_3863752_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000179 271.0
MMD2_k127_3863752_11 RNA polymerase K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000001094 251.0
MMD2_k127_3863752_12 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000000000001434 214.0
MMD2_k127_3863752_13 PFAM peptidase M55 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000139 213.0
MMD2_k127_3863752_14 CarboxypepD_reg-like domain K13276 GO:0005575,GO:0005576 - 0.00000000000000000000000000000000000000000000000000000003151 216.0
MMD2_k127_3863752_15 sporulation resulting in formation of a cellular spore K06381 - - 0.0000000000000000000000000000000000000000000000000001944 201.0
MMD2_k127_3863752_16 PFAM phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000002755 184.0
MMD2_k127_3863752_17 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000001045 181.0
MMD2_k127_3863752_18 diguanylate cyclase - - - 0.000000000000000000000000000000000002803 153.0
MMD2_k127_3863752_19 Transposase IS200 like K07491 - - 0.000000000000000000000000001293 122.0
MMD2_k127_3863752_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 496.0
MMD2_k127_3863752_20 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043021,GO:0043022,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1902626,GO:1990904 - 0.000000000000000000000000007485 111.0
MMD2_k127_3863752_21 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000005451 115.0
MMD2_k127_3863752_22 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000167 102.0
MMD2_k127_3863752_23 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000001886 106.0
MMD2_k127_3863752_24 DNA polymerase III K02341 - 2.7.7.7 0.00000000000000000004286 101.0
MMD2_k127_3863752_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA - - - 0.0000000000000005238 85.0
MMD2_k127_3863752_26 Protein of unknown function (DUF503) - - - 0.000000000193 66.0
MMD2_k127_3863752_27 Preprotein translocase SecG subunit K03075 - - 0.000000008293 61.0
MMD2_k127_3863752_28 guanyl-nucleotide exchange factor activity - - - 0.000000479 62.0
MMD2_k127_3863752_29 FlgD Ig-like domain - - - 0.0006302 52.0
MMD2_k127_3863752_3 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 440.0
MMD2_k127_3863752_4 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134,K00150 - 1.2.1.12,1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 435.0
MMD2_k127_3863752_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 376.0
MMD2_k127_3863752_6 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 363.0
MMD2_k127_3863752_7 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 318.0
MMD2_k127_3863752_8 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 291.0
MMD2_k127_3863752_9 Participates in both transcription termination and antitermination K02600 GO:0001000,GO:0001121,GO:0001125,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043175,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070063,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 295.0
MMD2_k127_3863780_0 Subtilase family K17734 - - 0.000000000000000000000000000000000000000000000000009956 202.0
MMD2_k127_3909114_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003625 279.0
MMD2_k127_3909114_1 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000002203 177.0
MMD2_k127_3909114_2 ORF6N domain - - - 0.00000000000000000000000000000000000000005113 158.0
MMD2_k127_3909114_3 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000007499 142.0
MMD2_k127_3909114_4 - - - - 0.000000000000006966 80.0
MMD2_k127_3909114_5 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000001157 63.0
MMD2_k127_3956946_0 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 437.0
MMD2_k127_3956946_1 - K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 347.0
MMD2_k127_3956946_2 2 iron, 2 sulfur cluster binding K00528,K02823,K16951 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001352 259.0
MMD2_k127_3956946_3 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.0000000000000000000000000000000000000000000000000000000001251 222.0
MMD2_k127_3956946_4 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family - - - 0.00000000000000000000000000000000000000000000000009959 190.0
MMD2_k127_3956946_5 Belongs to the complex I 20 kDa subunit family K18023 - 1.12.7.2 0.0000000000000000000000000000000000000000000000102 175.0
MMD2_k127_3956946_6 Cupin - - - 0.00000000000000000000000000000000837 132.0
MMD2_k127_3956946_7 4Fe-4S dicluster domain - - - 0.0000000000000000000004559 107.0
MMD2_k127_3956946_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000001549 101.0
MMD2_k127_3956946_9 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00372 - - 0.0000000000004401 83.0
MMD2_k127_3970088_0 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009596 320.0
MMD2_k127_3970088_1 PKD domain - - - 0.000000000000000000000002983 114.0
MMD2_k127_3970088_2 PKD domain - - - 0.000002799 53.0
MMD2_k127_4012021_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 534.0
MMD2_k127_4058917_0 Tetratricopeptide repeat - - - 0.0000000000000000000001447 112.0
MMD2_k127_4058917_1 diguanylate cyclase - - - 0.000000000000008905 76.0
MMD2_k127_4058943_0 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000003596 175.0
MMD2_k127_4058943_1 Tetratricopeptide repeat - - - 0.0000000000000000000002708 111.0
MMD2_k127_4058943_2 diguanylate cyclase - - - 0.000000000000008905 76.0
MMD2_k127_4070088_0 Belongs to the ClpA ClpB family K03696 - - 6.412e-308 962.0
MMD2_k127_4070088_1 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 518.0
MMD2_k127_4070088_10 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004269 288.0
MMD2_k127_4070088_11 Mur ligase middle domain K01932 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000774 259.0
MMD2_k127_4070088_12 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000007872 237.0
MMD2_k127_4070088_13 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001025 240.0
MMD2_k127_4070088_14 - - - - 0.0000000000000000000000000000000000000000000000000000004267 212.0
MMD2_k127_4070088_15 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000003423 198.0
MMD2_k127_4070088_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009314,GO:0009628,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000000000000000000000001127 179.0
MMD2_k127_4070088_17 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000044 173.0
MMD2_k127_4070088_18 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000007286 163.0
MMD2_k127_4070088_19 COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.000000000000000000000000000000000000000001084 175.0
MMD2_k127_4070088_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 394.0
MMD2_k127_4070088_20 LVIVD repeat - - - 0.0000000000000000000000000000000000000003152 161.0
MMD2_k127_4070088_21 diguanylate cyclase - - - 0.00000000000000000000000000000000000000307 159.0
MMD2_k127_4070088_22 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000001408 161.0
MMD2_k127_4070088_23 Capsule biosynthesis CapC K22116 - - 0.0000000000000000000000000000003146 134.0
MMD2_k127_4070088_24 protein related to plant photosystem II stability assembly factor - - - 0.0000000000000000000000001702 120.0
MMD2_k127_4070088_25 Peptidase family M54 K06974 - - 0.000000000000000000009449 104.0
MMD2_k127_4070088_26 PFAM DivIVA family protein K04074 - - 0.00000000000000000002574 97.0
MMD2_k127_4070088_27 Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000005025 87.0
MMD2_k127_4070088_28 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000761 73.0
MMD2_k127_4070088_29 - - - - 0.00000000001999 76.0
MMD2_k127_4070088_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 341.0
MMD2_k127_4070088_30 Tetratricopeptide repeat-like domain - - - 0.000002991 58.0
MMD2_k127_4070088_31 Lamin Tail Domain - - - 0.00000778 57.0
MMD2_k127_4070088_32 Galactose oxidase, central domain - - - 0.0000871 55.0
MMD2_k127_4070088_33 extracellular matrix structural constituent - - - 0.0005352 54.0
MMD2_k127_4070088_34 Glycosyl hydrolase family 70 K01142,K01176 - 3.1.11.2,3.2.1.1 0.0006316 53.0
MMD2_k127_4070088_35 Histidine kinase - - - 0.0007687 52.0
MMD2_k127_4070088_4 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 334.0
MMD2_k127_4070088_5 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 335.0
MMD2_k127_4070088_6 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 314.0
MMD2_k127_4070088_7 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002706 284.0
MMD2_k127_4070088_8 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
MMD2_k127_4070088_9 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008504 293.0
MMD2_k127_4102920_0 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 581.0
MMD2_k127_4102920_1 General secretory system II protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 547.0
MMD2_k127_4102920_10 Lipoprotein K05811 - - 0.000000000000937 73.0
MMD2_k127_4102920_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 379.0
MMD2_k127_4102920_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 353.0
MMD2_k127_4102920_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 354.0
MMD2_k127_4102920_5 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 337.0
MMD2_k127_4102920_6 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 322.0
MMD2_k127_4102920_7 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000004986 188.0
MMD2_k127_4102920_8 Ecdysteroid kinase K07102 - 2.7.1.221 0.000000000000000000000000000000000001974 155.0
MMD2_k127_4102920_9 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000001266 132.0
MMD2_k127_4173726_0 Phytoene dehydrogenase and related proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 516.0
MMD2_k127_4173726_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001666 272.0
MMD2_k127_4173726_10 - - - - 0.000000000000000000000000001037 121.0
MMD2_k127_4173726_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000005791 108.0
MMD2_k127_4173726_12 metallocarboxypeptidase activity K00368,K22348,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000000001319 106.0
MMD2_k127_4173726_13 long-chain fatty acid transporting porin activity - - - 0.0000000000000000083 98.0
MMD2_k127_4173726_14 Sigma factor PP2C-like phosphatases K04757,K07315 - 2.7.11.1,3.1.3.3 0.0000000000000002156 85.0
MMD2_k127_4173726_15 Anti-sigma factor antagonist K02066,K04749 - - 0.0000000000006179 77.0
MMD2_k127_4173726_16 Evidence 5 No homology to any previously reported sequences - - - 0.00000000001934 68.0
MMD2_k127_4173726_17 40-residue YVTN family beta-propeller repeat - - - 0.00000002827 65.0
MMD2_k127_4173726_18 bacterial-type flagellum-dependent cell motility - - - 0.0000003631 61.0
MMD2_k127_4173726_19 flavoprotein involved in K transport - - - 0.00005483 53.0
MMD2_k127_4173726_2 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005095 258.0
MMD2_k127_4173726_20 arabinogalactan endo-1,4-beta-galactosidase activity K01224 - 3.2.1.89 0.0002519 53.0
MMD2_k127_4173726_21 Protein of unknown function (DUF3494) - - - 0.000319 55.0
MMD2_k127_4173726_3 Sigma factor PP2C-like phosphatases K04757,K07315 - 2.7.11.1,3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000155 267.0
MMD2_k127_4173726_4 PFAM peptidase M6, immune inhibitor A - - - 0.000000000000000000000000000000000000000000000000000000000000104 234.0
MMD2_k127_4173726_5 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000000000000000000000000000000000007474 229.0
MMD2_k127_4173726_6 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.0000000000000000000000000000000000000000002057 176.0
MMD2_k127_4173726_7 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000000006264 139.0
MMD2_k127_4173726_8 amine dehydrogenase activity - - - 0.0000000000000000000000000002112 131.0
MMD2_k127_4173726_9 Transposase IS200 like K07491 - - 0.0000000000000000000000000006124 124.0
MMD2_k127_4183200_0 NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 503.0
MMD2_k127_4183200_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004985 344.0
MMD2_k127_4183200_10 NUDIX domain - - - 0.000000000000000000000000000000000001377 152.0
MMD2_k127_4183200_11 Cupin domain - - - 0.000000000000000000000000000000000004221 139.0
MMD2_k127_4183200_12 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000003709 111.0
MMD2_k127_4183200_13 cell adhesion involved in biofilm formation K02453 - - 0.00000000001764 72.0
MMD2_k127_4183200_14 - - - - 0.00000001881 57.0
MMD2_k127_4183200_15 - - - - 0.0000008507 51.0
MMD2_k127_4183200_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 329.0
MMD2_k127_4183200_3 Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate K03473 - 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000000366 278.0
MMD2_k127_4183200_4 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000754 272.0
MMD2_k127_4183200_5 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005548 257.0
MMD2_k127_4183200_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000008457 244.0
MMD2_k127_4183200_7 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000000000000000000000000000000000000114 193.0
MMD2_k127_4183200_8 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.00000000000000000000000000000000000000000000001212 179.0
MMD2_k127_4183200_9 Methyltransferase small domain - - - 0.000000000000000000000000000000000000000000001282 174.0
MMD2_k127_4309366_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K06987,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000007648 208.0
MMD2_k127_4309366_1 peptidase activity, acting on L-amino acid peptides K07752 - 3.4.17.22 0.000007137 53.0
MMD2_k127_4309366_2 - - - - 0.0004238 53.0
MMD2_k127_4327701_0 Clp amino terminal domain, pathogenicity island component K03696 - - 1.236e-293 921.0
MMD2_k127_4327701_1 Mur ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000684 470.0
MMD2_k127_4327701_10 Type II secretory pathway component ExeA K02450 - - 0.00000000000000000000000000000000000000000000000000003104 197.0
MMD2_k127_4327701_11 Tetratricopeptide repeat K11935 - - 0.000000000000000000000000000000000000000000006919 182.0
MMD2_k127_4327701_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000001192 161.0
MMD2_k127_4327701_13 Methyl-accepting chemotaxis protein (MCP) signaling domain K03406 - - 0.000000000000000000000000000000000000007893 163.0
MMD2_k127_4327701_14 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000003672 138.0
MMD2_k127_4327701_15 - - - - 0.000000000000000000000000001829 121.0
MMD2_k127_4327701_18 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000000000000006915 113.0
MMD2_k127_4327701_19 Radical SAM domain protein - - - 0.0000000000000000000009509 109.0
MMD2_k127_4327701_2 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 459.0
MMD2_k127_4327701_20 Rubredoxin - - - 0.000000000000000000003498 94.0
MMD2_k127_4327701_21 PFAM thioesterase superfamily - - - 0.000000000000000000004871 99.0
MMD2_k127_4327701_22 PFAM CheW domain protein K03408 - - 0.00000000003448 74.0
MMD2_k127_4327701_23 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - 0.00000000027 70.0
MMD2_k127_4327701_24 - - - - 0.00000007446 61.0
MMD2_k127_4327701_25 Peptidase family C25 - - - 0.0000007485 61.0
MMD2_k127_4327701_26 Two component signalling adaptor domain K03408 - - 0.00003841 57.0
MMD2_k127_4327701_27 Anti-sigma-K factor rskA - - - 0.00004886 53.0
MMD2_k127_4327701_28 metallocarboxypeptidase activity K01206,K01218 - 3.2.1.51,3.2.1.78 0.0001251 55.0
MMD2_k127_4327701_29 Peptidase family C25 - - - 0.0004725 51.0
MMD2_k127_4327701_3 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 408.0
MMD2_k127_4327701_4 PFAM CobB CobQ-like glutamine amidotransferase K07009 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 320.0
MMD2_k127_4327701_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K14441 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016782,GO:0018193,GO:0018197,GO:0018198,GO:0018339,GO:0019538,GO:0035596,GO:0035599,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050497,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901564 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 312.0
MMD2_k127_4327701_6 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 309.0
MMD2_k127_4327701_7 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000002264 246.0
MMD2_k127_4327701_8 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000002268 208.0
MMD2_k127_4327701_9 PFAM Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000000000000000000001805 206.0
MMD2_k127_4344064_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 6.1e-230 730.0
MMD2_k127_4344064_1 Isocitrate/isopropylmalate dehydrogenase K00030,K00052 - 1.1.1.41,1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005454 563.0
MMD2_k127_4344064_10 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003073 286.0
MMD2_k127_4344064_11 PFAM tRNA pseudouridine synthase D TruD K06176 - 5.4.99.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005417 280.0
MMD2_k127_4344064_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000008859 263.0
MMD2_k127_4344064_13 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002648 262.0
MMD2_k127_4344064_14 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000001738 244.0
MMD2_k127_4344064_15 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000006658 229.0
MMD2_k127_4344064_16 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000000000000001889 189.0
MMD2_k127_4344064_17 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000001448 163.0
MMD2_k127_4344064_18 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000239 162.0
MMD2_k127_4344064_19 methyltransferase - - - 0.0000000000000000000000000000000000000001899 161.0
MMD2_k127_4344064_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 520.0
MMD2_k127_4344064_20 - - - - 0.00000000000000000000000000000000001291 153.0
MMD2_k127_4344064_21 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000005967 132.0
MMD2_k127_4344064_22 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000004885 113.0
MMD2_k127_4344064_23 Protein of unknown function (DUF3108) - - - 0.00000000000000000001026 100.0
MMD2_k127_4344064_24 Belongs to the UPF0235 family K09131 - - 0.00000000002221 67.0
MMD2_k127_4344064_25 PFAM phospholipase Carboxylesterase K06999 - - 0.0000000009924 70.0
MMD2_k127_4344064_26 metalloendopeptidase activity K03799 - - 0.00000003647 66.0
MMD2_k127_4344064_27 Sporulation related domain - - - 0.000002395 57.0
MMD2_k127_4344064_28 - - - - 0.00001427 56.0
MMD2_k127_4344064_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 452.0
MMD2_k127_4344064_4 uridine kinase K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 376.0
MMD2_k127_4344064_5 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 354.0
MMD2_k127_4344064_6 AIR synthase related protein, N-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004771 332.0
MMD2_k127_4344064_7 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 349.0
MMD2_k127_4344064_8 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 338.0
MMD2_k127_4344064_9 Peptidogalycan biosysnthesis/recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 306.0
MMD2_k127_4359941_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000009281 263.0
MMD2_k127_4359941_1 tetratricopeptide repeat - - - 0.00000000000000000000000000000004069 130.0
MMD2_k127_4359941_2 LUD domain - - - 0.00000000000000001217 84.0
MMD2_k127_4434376_0 ammonia-lyase activity K01745 - 4.3.1.3 2.226e-265 824.0
MMD2_k127_4434376_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 4.76e-215 676.0
MMD2_k127_4434376_10 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 411.0
MMD2_k127_4434376_11 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 394.0
MMD2_k127_4434376_12 Phosphate acetyl/butaryl transferase K00634,K13788 - 2.3.1.19,2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 377.0
MMD2_k127_4434376_13 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004056 359.0
MMD2_k127_4434376_14 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 331.0
MMD2_k127_4434376_15 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 310.0
MMD2_k127_4434376_16 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005222 310.0
MMD2_k127_4434376_17 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000004511 275.0
MMD2_k127_4434376_18 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000377 265.0
MMD2_k127_4434376_19 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004358 252.0
MMD2_k127_4434376_2 Dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 532.0
MMD2_k127_4434376_20 O-acyltransferase activity K13018 - 2.3.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000111 239.0
MMD2_k127_4434376_21 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001852 244.0
MMD2_k127_4434376_22 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000008748 210.0
MMD2_k127_4434376_23 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000026 203.0
MMD2_k127_4434376_24 PFAM sugar transferase - - - 0.0000000000000000000000000000000000000000000000000003205 201.0
MMD2_k127_4434376_25 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000006394 183.0
MMD2_k127_4434376_26 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000001379 184.0
MMD2_k127_4434376_27 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000007331 184.0
MMD2_k127_4434376_28 CGGC - - - 0.000000000000000000000000000000000000009025 151.0
MMD2_k127_4434376_29 UbiA prenyltransferase family K03179,K04040 - 2.5.1.133,2.5.1.39,2.5.1.62 0.00000000000000000000000000000000000001404 156.0
MMD2_k127_4434376_3 Threonine synthase N terminus K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009088,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 539.0
MMD2_k127_4434376_30 Capsule assembly protein Wzi - - - 0.00000000000000000000000000005629 132.0
MMD2_k127_4434376_31 PFAM Methyltransferase domain - - - 0.0009869 49.0
MMD2_k127_4434376_4 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 510.0
MMD2_k127_4434376_5 Acetokinase family K00929 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0044237,GO:0044424,GO:0044464,GO:0047761 2.7.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005346 490.0
MMD2_k127_4434376_6 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 474.0
MMD2_k127_4434376_7 PFAM Cys Met metabolism K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000651 472.0
MMD2_k127_4434376_8 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 462.0
MMD2_k127_4434376_9 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 420.0
MMD2_k127_4446632_0 PFAM Peptidase C1A, papain - - - 0.0000000000000000000000000000000000000000000000003443 203.0
MMD2_k127_4446632_1 Glycosyl hydrolase-like 10 - - - 0.000000000000000000000000000002974 138.0
MMD2_k127_4446632_2 TIGRFAM TIGR03442 family protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006518,GO:0006575,GO:0006749,GO:0006751,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0032991,GO:0034641,GO:0042219,GO:0043171,GO:0043603,GO:0044237,GO:0044248,GO:0044273,GO:0044424,GO:0044464,GO:0051186,GO:0051187,GO:0061672,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368 - 0.00000001542 66.0
MMD2_k127_4446632_3 peptidase activity, acting on L-amino acid peptides K09607 - - 0.0000001276 60.0
MMD2_k127_4446632_4 Cytochrome c - - - 0.000317 55.0
MMD2_k127_4446632_5 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.0006407 49.0
MMD2_k127_4451947_0 Neisseria PilC beta-propeller domain K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 517.0
MMD2_k127_4451947_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000007173 248.0
MMD2_k127_4451947_2 self proteolysis - - - 0.000000000000769 79.0
MMD2_k127_4451947_3 Prokaryotic N-terminal methylation motif K02671 - - 0.000000387 59.0
MMD2_k127_4451947_4 Prokaryotic N-terminal methylation motif - - - 0.000002107 59.0
MMD2_k127_4455188_0 NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006769 255.0
MMD2_k127_4455188_1 Photosynthesis system II assembly factor YCF48 - - - 0.0000000000000000000000000000001415 139.0
MMD2_k127_4455188_10 cellulose binding - - - 0.00001368 57.0
MMD2_k127_4455188_3 Phosphate acyltransferases - - - 0.000000000000000000000006302 117.0
MMD2_k127_4455188_4 ORF6N domain - - - 0.000000000000000000006207 95.0
MMD2_k127_4455188_5 Bacterial transcriptional activator domain - - - 0.0000000000000000001669 104.0
MMD2_k127_4455188_6 ORF6N domain - - - 0.0000000000000003546 79.0
MMD2_k127_4455188_7 Transglutaminase/protease-like homologues K01406 - 3.4.24.40 0.0000000003406 71.0
MMD2_k127_4455188_8 metallopeptidase activity K01179 - 3.2.1.4 0.00000001934 63.0
MMD2_k127_4455188_9 Phospholipid methyltransferase - - - 0.0000005929 62.0
MMD2_k127_4460765_0 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 308.0
MMD2_k127_4460765_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000006875 209.0
MMD2_k127_4460765_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000002063 198.0
MMD2_k127_4460765_3 Surface antigen K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.0000000000000000000000000000000000006974 158.0
MMD2_k127_4460765_4 Family of K09800 - - 0.00000517 60.0
MMD2_k127_4503319_0 DNA topoisomerase II activity K02469 - 5.99.1.3 7.873e-269 850.0
MMD2_k127_4503319_1 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000275 206.0
MMD2_k127_4503319_2 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.000000000000000000000000000000000000000000000000000002306 210.0
MMD2_k127_4503319_3 NYN domain - - - 0.000000000000000000000000000000000000000471 160.0
MMD2_k127_4503319_4 Peptidase M56 - - - 0.0000000000000000000000000000005154 135.0
MMD2_k127_4503319_5 - - - - 0.0000000000000000000007871 112.0
MMD2_k127_4503319_6 - - - - 0.000001416 52.0
MMD2_k127_4593109_0 B12 binding domain - - - 7.72e-202 638.0
MMD2_k127_4593109_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 592.0
MMD2_k127_4593109_10 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009177 264.0
MMD2_k127_4593109_11 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001342 271.0
MMD2_k127_4593109_12 DNA-templated transcription, initiation K03088,K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002514 263.0
MMD2_k127_4593109_13 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000504 256.0
MMD2_k127_4593109_14 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001151 271.0
MMD2_k127_4593109_15 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000007432 233.0
MMD2_k127_4593109_16 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000000000000000000002606 200.0
MMD2_k127_4593109_17 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000009137 196.0
MMD2_k127_4593109_18 - - - - 0.000000000000000000000000000000000000000000000000000001663 199.0
MMD2_k127_4593109_19 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000009068 200.0
MMD2_k127_4593109_2 SPFH Band 7 PHB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008222 438.0
MMD2_k127_4593109_20 superoxide reductase activity K05919 - 1.15.1.2 0.00000000000000000000000000000000000000000000000001238 183.0
MMD2_k127_4593109_21 LysM domain - - - 0.00000000000000000000000000000000000000000000000009754 185.0
MMD2_k127_4593109_22 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000001732 174.0
MMD2_k127_4593109_23 Protein of unknown function, DUF488 - - - 0.000000000000000000000000000000000000000000005891 166.0
MMD2_k127_4593109_24 MarR family - - - 0.00000000000000000000000000000000000000000005312 166.0
MMD2_k127_4593109_25 Histidine kinase - - - 0.00000000000000000000000000000000000000001079 175.0
MMD2_k127_4593109_26 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000135 175.0
MMD2_k127_4593109_27 HD domain - - - 0.0000000000000000000000000000000000000003537 159.0
MMD2_k127_4593109_28 - - - - 0.000000000000000000000000000000000000001745 153.0
MMD2_k127_4593109_29 Histidine kinase - - - 0.0000000000000000000000000000000000008713 162.0
MMD2_k127_4593109_3 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 403.0
MMD2_k127_4593109_30 secondary active sulfate transmembrane transporter activity - - - 0.0000000000000000000000000000000000048 145.0
MMD2_k127_4593109_31 protein kinase activity - - - 0.0000000000000000000000004377 114.0
MMD2_k127_4593109_32 Psort location Cytoplasmic, score K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0010181,GO:0016491,GO:0016651,GO:0016661,GO:0016662,GO:0016966,GO:0022900,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0050664,GO:0055114,GO:0072593,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.3.4 0.000000000000000000008136 92.0
MMD2_k127_4593109_33 PAS fold - - - 0.00000000000000000008283 103.0
MMD2_k127_4593109_34 COG3417 Collagen-binding surface adhesin SpaP (antigen I II family) K07337 - - 0.0000000000000000002999 95.0
MMD2_k127_4593109_35 Universal stress protein - - - 0.0000000000000004536 85.0
MMD2_k127_4593109_36 Copper binding proteins, plastocyanin/azurin family - - - 0.000000000000006501 83.0
MMD2_k127_4593109_37 cellulase activity K01179,K01361,K13277,K21449 - 3.2.1.4,3.4.21.96 0.00000000000002835 86.0
MMD2_k127_4593109_38 Multicopper oxidase - - - 0.00000000000009793 76.0
MMD2_k127_4593109_39 Short C-terminal domain K08982 - - 0.0000000000002097 75.0
MMD2_k127_4593109_4 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 395.0
MMD2_k127_4593109_40 cellulose binding K00505 - 1.14.18.1 0.0000000000124 73.0
MMD2_k127_4593109_41 determination of stomach left/right asymmetry K10407 - - 0.00000000002337 76.0
MMD2_k127_4593109_42 Evidence 5 No homology to any previously reported sequences - - - 0.0000000003806 68.0
MMD2_k127_4593109_43 Peptidase_C39 like family - - - 0.00000000249 71.0
MMD2_k127_4593109_44 Multicopper oxidase - - - 0.00000001819 63.0
MMD2_k127_4593109_45 - - - - 0.00000002354 62.0
MMD2_k127_4593109_46 Evidence 5 No homology to any previously reported sequences - - - 0.0000001033 61.0
MMD2_k127_4593109_47 - - - - 0.0000001033 61.0
MMD2_k127_4593109_48 cellulose binding - - - 0.00000182 59.0
MMD2_k127_4593109_49 COG NOG33517 non supervised orthologous group - - - 0.000006202 54.0
MMD2_k127_4593109_5 Adenylate K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 408.0
MMD2_k127_4593109_50 cellulose binding - - - 0.0000636 55.0
MMD2_k127_4593109_51 Two component regulator propeller - - - 0.0001635 54.0
MMD2_k127_4593109_52 Evidence 5 No homology to any previously reported sequences - - - 0.0002437 51.0
MMD2_k127_4593109_53 CheY-like receiver AAA-type ATPase and DNA-binding domains - - - 0.0003365 45.0
MMD2_k127_4593109_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 374.0
MMD2_k127_4593109_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 377.0
MMD2_k127_4593109_8 Protein of unknown function (DUF3089) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 337.0
MMD2_k127_4593109_9 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004314 293.0
MMD2_k127_4689357_0 silver ion transport K07787,K15726 - - 0.0 1350.0
MMD2_k127_4689357_1 ATP dependent DNA ligase C terminal region K01971 - 6.5.1.1 7.789e-238 759.0
MMD2_k127_4689357_10 Ku70/Ku80 beta-barrel domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004674 249.0
MMD2_k127_4689357_11 3-demethylubiquinone-9 3-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000003377 223.0
MMD2_k127_4689357_12 Conserved protein of DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000000000004474 209.0
MMD2_k127_4689357_13 chromosome segregation K03497 - - 0.0000000000000000000000000000000000000000000000000000008556 205.0
MMD2_k127_4689357_14 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000006962 191.0
MMD2_k127_4689357_15 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000001791 183.0
MMD2_k127_4689357_16 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000000000000002105 174.0
MMD2_k127_4689357_17 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000056 151.0
MMD2_k127_4689357_18 Mu-like prophage protein Gp16 - - - 0.000000000000000000000000000000001655 143.0
MMD2_k127_4689357_19 - - - - 0.000000000000000000000000000000004459 133.0
MMD2_k127_4689357_2 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 519.0
MMD2_k127_4689357_20 - - - - 0.00000000000000000000000000000005361 130.0
MMD2_k127_4689357_21 Domain of unknown function (DU1801) - - - 0.000000000000000000000000000007449 123.0
MMD2_k127_4689357_22 related to archaeal Holliday junction resolvase - - - 0.000000000000000000000000000746 121.0
MMD2_k127_4689357_23 RDD family - - - 0.000000000000000000000000001141 129.0
MMD2_k127_4689357_24 isochorismatase - - - 0.000000000000000000000000001769 118.0
MMD2_k127_4689357_25 Thiamine-binding protein - - - 0.000000000000000000000000003112 113.0
MMD2_k127_4689357_26 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000002674 108.0
MMD2_k127_4689357_27 Subtilase family - - - 0.000000000000000000001263 109.0
MMD2_k127_4689357_28 Outer membrane efflux protein - - - 0.000000000000000000001845 108.0
MMD2_k127_4689357_29 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000002259 102.0
MMD2_k127_4689357_3 Belongs to the helicase family. UvrD subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 504.0
MMD2_k127_4689357_30 - - - - 0.0000000000000001719 89.0
MMD2_k127_4689357_31 - - - - 0.000000000000001572 85.0
MMD2_k127_4689357_32 Endonuclease related to archaeal Holliday junction resolvase - - - 0.000000000000002342 82.0
MMD2_k127_4689357_33 Putative zinc ribbon domain - - - 0.0000000000003462 79.0
MMD2_k127_4689357_34 Phage derived protein Gp49-like (DUF891) - - - 0.00000000004396 68.0
MMD2_k127_4689357_35 ATPase family associated with various cellular activities (AAA) - - - 0.0000000002404 72.0
MMD2_k127_4689357_37 Domain of unknown function (DUF4652) - - - 0.000000002733 67.0
MMD2_k127_4689357_38 PD-(D/E)XK nuclease superfamily - - - 0.000000004359 65.0
MMD2_k127_4689357_39 PFAM Bacterial regulatory proteins, tetR family - - - 0.00000001883 65.0
MMD2_k127_4689357_4 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 493.0
MMD2_k127_4689357_40 Helix-turn-helix domain - - - 0.00000006533 59.0
MMD2_k127_4689357_41 Galactose oxidase, central domain - - - 0.00000007318 63.0
MMD2_k127_4689357_42 - - - - 0.0000004597 58.0
MMD2_k127_4689357_43 cellulose binding - - - 0.00001883 57.0
MMD2_k127_4689357_45 PD-(D/E)XK nuclease superfamily - - - 0.00002384 56.0
MMD2_k127_4689357_46 Double zinc ribbon - - - 0.0008007 44.0
MMD2_k127_4689357_5 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 422.0
MMD2_k127_4689357_6 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 407.0
MMD2_k127_4689357_7 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 325.0
MMD2_k127_4689357_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 308.0
MMD2_k127_4689357_9 zinc ion binding K06885,K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004124 284.0
MMD2_k127_4779384_0 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000211 214.0
MMD2_k127_4779384_1 Protein of unknown function (DUF3419) K13622 - - 0.00000000000000000000000000000000000000000000000000000001764 210.0
MMD2_k127_4779384_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000003121 225.0
MMD2_k127_4779384_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000005388 101.0
MMD2_k127_4779384_4 Haemolytic - - - 0.000000003305 68.0
MMD2_k127_4779384_5 Tetratricopeptide repeat - - - 0.000002444 58.0
MMD2_k127_4799698_0 Pyruvate formate lyase-like K00656 - 2.3.1.54 5.197e-296 923.0
MMD2_k127_4799698_1 SMART Metal-dependent phosphohydrolase, HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001763 277.0
MMD2_k127_4799698_10 alginic acid biosynthetic process K20276 - - 0.00000000006635 74.0
MMD2_k127_4799698_11 Fibronectin type 3 domain - - - 0.000000749 60.0
MMD2_k127_4799698_12 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000004821 60.0
MMD2_k127_4799698_13 - - - - 0.0004607 52.0
MMD2_k127_4799698_14 Phosphodiester glycosidase K05996 - 3.4.17.18 0.0004723 53.0
MMD2_k127_4799698_2 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000008414 252.0
MMD2_k127_4799698_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005087 256.0
MMD2_k127_4799698_4 ferredoxin iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000002183 202.0
MMD2_k127_4799698_5 domain, Protein - - - 0.00000000000000000000000000000000000008858 157.0
MMD2_k127_4799698_6 Peptidase family M28 K05994 - 3.4.11.10 0.00000000000000000000000000006552 133.0
MMD2_k127_4799698_7 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.00000000000000000000000009536 121.0
MMD2_k127_4799698_8 cellulose binding - - - 0.00000000000000000002798 102.0
MMD2_k127_4799698_9 amine dehydrogenase activity K12287 - - 0.000000000002227 79.0
MMD2_k127_4819398_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 579.0
MMD2_k127_4819398_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000787 418.0
MMD2_k127_4819398_10 WD40-like Beta Propeller Repeat - - - 0.000000005121 70.0
MMD2_k127_4819398_11 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000003997 62.0
MMD2_k127_4819398_12 cellulose binding K01179,K21449 - 3.2.1.4 0.0000005304 61.0
MMD2_k127_4819398_13 PFAM Tetratricopeptide - - - 0.000003097 60.0
MMD2_k127_4819398_14 Two component regulator propeller domain protein - - - 0.0002926 46.0
MMD2_k127_4819398_2 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 373.0
MMD2_k127_4819398_3 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 335.0
MMD2_k127_4819398_4 Alkyl hydroperoxide reductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 311.0
MMD2_k127_4819398_5 Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007022 278.0
MMD2_k127_4819398_6 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004615 273.0
MMD2_k127_4819398_7 Flavodoxin - - - 0.0000000000000000000000000008467 118.0
MMD2_k127_4819398_8 - - - - 0.0000000000000004096 93.0
MMD2_k127_4851476_0 BadF BadG BcrA BcrD - - - 4.25e-254 812.0
MMD2_k127_4851476_1 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 1.462e-196 622.0
MMD2_k127_4851476_10 Asparaginase K01444,K13051 - 3.4.19.5,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000005271 241.0
MMD2_k127_4851476_11 RibD C-terminal domain K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000000000000000000000002217 224.0
MMD2_k127_4851476_12 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000004184 223.0
MMD2_k127_4851476_13 LVIVD repeat-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000006853 230.0
MMD2_k127_4851476_14 PFAM Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000008337 233.0
MMD2_k127_4851476_15 - - - - 0.0000000000000000000000000000000000000000000000000000000004367 220.0
MMD2_k127_4851476_16 TIGRFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000001151 220.0
MMD2_k127_4851476_17 - - - - 0.0000000000000000000000000000000000000000000000000000004646 200.0
MMD2_k127_4851476_18 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000007508 215.0
MMD2_k127_4851476_19 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000001199 187.0
MMD2_k127_4851476_2 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 432.0
MMD2_k127_4851476_20 - - - - 0.00000000000000000000000000000000000000000000001995 181.0
MMD2_k127_4851476_21 Hep Hag repeat protein - - - 0.000000000000000000000000000006856 136.0
MMD2_k127_4851476_22 bacteriocin transport K03562 - - 0.00000000000000000000000000002506 125.0
MMD2_k127_4851476_23 - - - - 0.00000000000000000000000000006571 117.0
MMD2_k127_4851476_24 FG-GAP repeat - - - 0.0000000000000000000000000003283 130.0
MMD2_k127_4851476_25 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000216 117.0
MMD2_k127_4851476_26 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000001255 101.0
MMD2_k127_4851476_27 Outer membrane lipoprotein - - - 0.000000000000000005673 93.0
MMD2_k127_4851476_28 TonB C terminal K03646,K03832 - - 0.00000000000000006602 89.0
MMD2_k127_4851476_29 Domain of unknown function (DUF4412) - - - 0.00000000000001303 83.0
MMD2_k127_4851476_3 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 396.0
MMD2_k127_4851476_30 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000002455 83.0
MMD2_k127_4851476_31 TonB-dependent receptor - - - 0.000000000004394 79.0
MMD2_k127_4851476_32 bacterial-type flagellum-dependent cell motility - - - 0.0000001774 62.0
MMD2_k127_4851476_33 Endonuclease I - - - 0.000004089 60.0
MMD2_k127_4851476_34 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000005261 52.0
MMD2_k127_4851476_35 porT protein - - - 0.0006139 49.0
MMD2_k127_4851476_36 Heparinase II III-like protein - - - 0.000642 49.0
MMD2_k127_4851476_4 aminopeptidase K01372 - 3.4.22.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006244 368.0
MMD2_k127_4851476_5 aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 344.0
MMD2_k127_4851476_6 peptide catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 321.0
MMD2_k127_4851476_7 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0009719,GO:0009987,GO:0010033,GO:0010243,GO:0015031,GO:0015833,GO:0015893,GO:0017038,GO:0019534,GO:0019904,GO:0022857,GO:0030288,GO:0030313,GO:0031975,GO:0032153,GO:0032991,GO:0033036,GO:0042221,GO:0042493,GO:0042597,GO:0042886,GO:0042891,GO:0043213,GO:0044464,GO:0044877,GO:0045184,GO:0046677,GO:0046678,GO:0050896,GO:0051179,GO:0051234,GO:0051716,GO:0055085,GO:0070887,GO:0071236,GO:0071237,GO:0071310,GO:0071417,GO:0071495,GO:0071702,GO:0071705,GO:1901652,GO:1901653,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 314.0
MMD2_k127_4851476_8 Peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
MMD2_k127_4851476_9 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001363 261.0
MMD2_k127_4885800_0 serine-type endopeptidase activity K08653 - 3.4.21.112 0.0000000000000000000000000000000000000000000000000000000004287 228.0
MMD2_k127_4885800_1 extracellular matrix structural constituent - - - 0.00000000000000000000007399 115.0
MMD2_k127_4885800_2 FlgD Ig-like domain - - - 0.000001979 56.0
MMD2_k127_4890195_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 473.0
MMD2_k127_4890195_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 373.0
MMD2_k127_4890195_10 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000005239 239.0
MMD2_k127_4890195_11 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000001877 225.0
MMD2_k127_4890195_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000002117 220.0
MMD2_k127_4890195_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000003442 194.0
MMD2_k127_4890195_14 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000009283 169.0
MMD2_k127_4890195_15 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001066 168.0
MMD2_k127_4890195_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000001009 163.0
MMD2_k127_4890195_17 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000001766 166.0
MMD2_k127_4890195_18 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000002896 156.0
MMD2_k127_4890195_19 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000004842 152.0
MMD2_k127_4890195_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 327.0
MMD2_k127_4890195_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000003799 144.0
MMD2_k127_4890195_21 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000003092 134.0
MMD2_k127_4890195_22 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000374 136.0
MMD2_k127_4890195_23 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000004251 131.0
MMD2_k127_4890195_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000008766 124.0
MMD2_k127_4890195_25 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000003076 123.0
MMD2_k127_4890195_26 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000002532 132.0
MMD2_k127_4890195_27 Ribosomal protein L17 K02879,K16193 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000006075 123.0
MMD2_k127_4890195_28 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000000000000000001281 93.0
MMD2_k127_4890195_29 Ribosomal protein L30p/L7e K02907 - - 0.000000000001138 70.0
MMD2_k127_4890195_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 309.0
MMD2_k127_4890195_30 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000657 63.0
MMD2_k127_4890195_31 Roadblock/LC7 domain - - - 0.0000000006333 65.0
MMD2_k127_4890195_32 RHS repeat-associated core domain - - - 0.0004327 53.0
MMD2_k127_4890195_4 N(6)-L-threonylcarbamoyladenine synthase activity K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
MMD2_k127_4890195_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000635 273.0
MMD2_k127_4890195_6 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000001035 262.0
MMD2_k127_4890195_7 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001997 270.0
MMD2_k127_4890195_8 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000005408 264.0
MMD2_k127_4890195_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000462 249.0
MMD2_k127_4966551_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 7.53e-242 770.0
MMD2_k127_4966551_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.894e-212 673.0
MMD2_k127_4966551_2 PFAM Capsule synthesis protein, CapA K07282 - - 0.000000000000000000000000000000000000004147 158.0
MMD2_k127_4966551_3 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0000000000000000000000000000001005 128.0
MMD2_k127_5054479_0 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001878 240.0
MMD2_k127_5054479_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000005042 222.0
MMD2_k127_5054479_10 - - - - 0.0001211 45.0
MMD2_k127_5054479_11 transcriptional K22043 - - 0.0003761 47.0
MMD2_k127_5054479_3 cell redox homeostasis K02199 - - 0.0000000000000000000000000004768 121.0
MMD2_k127_5054479_4 OsmC-like protein K07397 - - 0.0000000000000000000002758 101.0
MMD2_k127_5054479_5 - - - - 0.0000000000000000005435 88.0
MMD2_k127_5054479_6 Belongs to the thioredoxin family K03671 - - 0.000000000000000002652 89.0
MMD2_k127_5054479_7 - - - - 0.0000000000000001144 79.0
MMD2_k127_5054479_8 - - - - 0.0000000000009104 69.0
MMD2_k127_5054479_9 - - - - 0.00001595 48.0
MMD2_k127_5076279_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 2.409e-198 645.0
MMD2_k127_5076279_1 class II (D K and N) K01893 - 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008929 563.0
MMD2_k127_5076279_10 Leucyl aminopeptidase K19701 - 3.4.11.10,3.4.11.6 0.000000000000000000000074 114.0
MMD2_k127_5076279_11 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.0000000000000001264 91.0
MMD2_k127_5076279_12 hydrogenase assembly chaperone HypC HupF K04653 - - 0.00000000000003479 76.0
MMD2_k127_5076279_14 helix_turn_helix, arabinose operon control protein - - - 0.000000004429 70.0
MMD2_k127_5076279_15 cellulase activity K01387 - 3.4.24.3 0.00000001305 68.0
MMD2_k127_5076279_2 transferase activity, transferring glycosyl groups K00721,K03820 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002125 274.0
MMD2_k127_5076279_3 Evidence 5 No homology to any previously reported sequences K17713 - - 0.0000000000000000000000000000000000000000000000000000000000000000009037 259.0
MMD2_k127_5076279_4 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000005749 217.0
MMD2_k127_5076279_5 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000001294 226.0
MMD2_k127_5076279_6 Glycosyltransferase like family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000006009 203.0
MMD2_k127_5076279_7 Purple acid Phosphatase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000001655 197.0
MMD2_k127_5076279_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000001317 181.0
MMD2_k127_5076279_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000008128 105.0
MMD2_k127_5144671_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.754e-209 668.0
MMD2_k127_5144671_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 472.0
MMD2_k127_5144671_10 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005907 259.0
MMD2_k127_5144671_11 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000337 253.0
MMD2_k127_5144671_12 PcrB family K07094 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008595 246.0
MMD2_k127_5144671_13 glucokinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000001656 229.0
MMD2_k127_5144671_14 Asparaginase K13051 - 3.4.19.5 0.000000000000000000000000000000000000000000000000000000000000007161 233.0
MMD2_k127_5144671_15 Sugar nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000009611 220.0
MMD2_k127_5144671_16 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774 - - 0.0000000000000000000000000000000000000000000000000000001499 218.0
MMD2_k127_5144671_17 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000264 199.0
MMD2_k127_5144671_18 TonB-dependent Receptor Plug K02014,K16089 - - 0.00000000000000000000000000000000000000000001769 184.0
MMD2_k127_5144671_19 Belongs to the SUA5 family K01104,K01808,K07566,K20201 GO:0000049,GO:0000166,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008144,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034470,GO:0034641,GO:0034660,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363 2.7.7.87,3.1.3.48,3.9.1.2,5.3.1.6 0.0000000000000000000000000000000000000000003382 171.0
MMD2_k127_5144671_2 phosphopentomutase activity K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004514 458.0
MMD2_k127_5144671_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000002272 162.0
MMD2_k127_5144671_21 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000001509 150.0
MMD2_k127_5144671_22 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000004387 149.0
MMD2_k127_5144671_23 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000001219 140.0
MMD2_k127_5144671_24 PFAM Forkhead-associated protein - - - 0.00000000000000000000000000000000003179 154.0
MMD2_k127_5144671_25 BioY protein K03523 - - 0.000000000000000000000000000005357 126.0
MMD2_k127_5144671_26 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000001689 115.0
MMD2_k127_5144671_27 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000001055 113.0
MMD2_k127_5144671_28 Multi-copper polyphenol oxidoreductase laccase K05810 - - 0.00000000000000000000003074 107.0
MMD2_k127_5144671_29 Kelch motif - - - 0.000000000000000001407 102.0
MMD2_k127_5144671_3 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 441.0
MMD2_k127_5144671_30 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K01802,K03770 - 5.2.1.8 0.000000000000000003391 99.0
MMD2_k127_5144671_31 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000002108 80.0
MMD2_k127_5144671_32 - - - - 0.000000000006079 70.0
MMD2_k127_5144671_33 cellulase activity - - - 0.000000000009594 79.0
MMD2_k127_5144671_34 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000003441 64.0
MMD2_k127_5144671_35 CarboxypepD_reg-like domain - - - 0.0000000007242 72.0
MMD2_k127_5144671_36 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000003706 56.0
MMD2_k127_5144671_37 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000004293 63.0
MMD2_k127_5144671_38 Subtilase family - - - 0.00004104 57.0
MMD2_k127_5144671_39 membrane K08978 - - 0.0000872 50.0
MMD2_k127_5144671_4 Thymidylate synthase complementing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 432.0
MMD2_k127_5144671_40 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0006177 53.0
MMD2_k127_5144671_5 TIGRFAM single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 429.0
MMD2_k127_5144671_6 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 402.0
MMD2_k127_5144671_7 Putative serine dehydratase domain K20757 - 4.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 392.0
MMD2_k127_5144671_8 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 407.0
MMD2_k127_5144671_9 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 372.0
MMD2_k127_5204266_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.331e-239 758.0
MMD2_k127_5204266_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 568.0
MMD2_k127_5204266_10 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001613 291.0
MMD2_k127_5204266_11 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002247 265.0
MMD2_k127_5204266_12 endonuclease III K07457 - - 0.0000000000000000000000000000000000000000000000000000000001331 211.0
MMD2_k127_5204266_13 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000003453 206.0
MMD2_k127_5204266_14 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000002983 192.0
MMD2_k127_5204266_15 Putative glycosyl hydrolase domain - - - 0.00000000000000000000000000000000000000000007956 174.0
MMD2_k127_5204266_16 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000002854 177.0
MMD2_k127_5204266_17 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000000000000000002444 152.0
MMD2_k127_5204266_18 Monogalactosyldiacylglycerol (MGDG) synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000001994 154.0
MMD2_k127_5204266_19 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.00000000000000000000000001099 112.0
MMD2_k127_5204266_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 532.0
MMD2_k127_5204266_20 Capsule assembly protein Wzi - - - 0.0000000000000000000000001156 123.0
MMD2_k127_5204266_21 PQQ enzyme repeat - - - 0.00000000000000000000002075 115.0
MMD2_k127_5204266_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000008987 105.0
MMD2_k127_5204266_23 Glycoside hydrolase family 24 - - - 0.000000000000000005625 100.0
MMD2_k127_5204266_24 lyase activity - - - 0.00000000000000002078 97.0
MMD2_k127_5204266_25 PFAM Uncharacterised protein family (UPF0164) - - - 0.0000000000000004724 91.0
MMD2_k127_5204266_26 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000005226 83.0
MMD2_k127_5204266_27 Protein of unknown function (DUF721) - - - 0.0000000000401 68.0
MMD2_k127_5204266_28 PFAM Methyltransferase domain K00568 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 2.1.1.222,2.1.1.64 0.00000000009336 72.0
MMD2_k127_5204266_29 Outer membrane protein beta-barrel family - - - 0.00000000158 66.0
MMD2_k127_5204266_3 PFAM UDP-glucose GDP-mannose dehydrogenase K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 483.0
MMD2_k127_5204266_30 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000002471 63.0
MMD2_k127_5204266_31 Propeptide_C25 - - - 0.0000007156 60.0
MMD2_k127_5204266_32 Anti-sigma-K factor rskA - - - 0.0005224 49.0
MMD2_k127_5204266_4 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 421.0
MMD2_k127_5204266_5 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 420.0
MMD2_k127_5204266_6 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 351.0
MMD2_k127_5204266_7 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 342.0
MMD2_k127_5204266_8 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 349.0
MMD2_k127_5204266_9 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007649 324.0
MMD2_k127_5232153_0 Alpha amylase, catalytic domain - - - 1.273e-289 917.0
MMD2_k127_5232153_1 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000001943 230.0
MMD2_k127_5232153_2 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000002372 206.0
MMD2_k127_5232153_3 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000002324 166.0
MMD2_k127_5232153_4 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000002947 85.0
MMD2_k127_5232153_5 lysine biosynthetic process via aminoadipic acid - - - 0.000000000629 72.0
MMD2_k127_5232153_6 - - - - 0.0000001532 61.0
MMD2_k127_5256361_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 1.922e-299 944.0
MMD2_k127_5256361_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 GO:0000166,GO:0000287,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009376,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019904,GO:0022607,GO:0030554,GO:0031597,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034214,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043335,GO:0043933,GO:0044085,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051259,GO:0065003,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 527.0
MMD2_k127_5256361_2 ABC transporter, transmembrane region K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001617 287.0
MMD2_k127_5256361_3 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000288 258.0
MMD2_k127_5256361_4 ABC transporter transmembrane region K18890 - - 0.0000000000000000000000000000000000000000000000000000000000004745 216.0
MMD2_k127_5256361_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008144,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000001439 172.0
MMD2_k127_5256361_6 PFAM ribonuclease H K03469,K06864 - 3.1.26.4 0.0000000000000000000000002672 111.0
MMD2_k127_5256361_7 C4-type zinc ribbon domain K07164,K22391 - 3.5.4.16 0.0000000000000000000001576 107.0
MMD2_k127_5256361_8 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000003249 104.0
MMD2_k127_5266080_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 345.0
MMD2_k127_5266080_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003071 269.0
MMD2_k127_5266080_10 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000001484 187.0
MMD2_k127_5266080_11 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000006494 195.0
MMD2_k127_5266080_12 UbiA prenyltransferase family K03179,K04040 - 2.5.1.133,2.5.1.39,2.5.1.62 0.0000000000000000000000000000000000000000000003511 179.0
MMD2_k127_5266080_13 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000146 128.0
MMD2_k127_5266080_14 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000001955 107.0
MMD2_k127_5266080_15 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000001989 85.0
MMD2_k127_5266080_16 Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family K10352 GO:0000146,GO:0000166,GO:0000278,GO:0000281,GO:0000302,GO:0000910,GO:0001891,GO:0001931,GO:0003674,GO:0003774,GO:0003779,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005826,GO:0005829,GO:0005856,GO:0005886,GO:0005938,GO:0006928,GO:0006935,GO:0006950,GO:0006970,GO:0006971,GO:0006979,GO:0006996,GO:0007010,GO:0007015,GO:0007033,GO:0007049,GO:0007154,GO:0008064,GO:0008092,GO:0008104,GO:0008144,GO:0008150,GO:0008360,GO:0009267,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009636,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010243,GO:0010639,GO:0014070,GO:0014074,GO:0015629,GO:0016020,GO:0016043,GO:0016050,GO:0016459,GO:0016460,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022402,GO:0022603,GO:0022604,GO:0022607,GO:0030029,GO:0030030,GO:0030031,GO:0030036,GO:0030038,GO:0030048,GO:0030139,GO:0030554,GO:0030587,GO:0030832,GO:0030833,GO:0030837,GO:0030863,GO:0030864,GO:0030865,GO:0030866,GO:0030898,GO:0031033,GO:0031034,GO:0031152,GO:0031154,GO:0031254,GO:0031268,GO:0031270,GO:0031333,GO:0031410,GO:0031667,GO:0031668,GO:0031669,GO:0031982,GO:0032009,GO:0032060,GO:0032153,GO:0032155,GO:0032271,GO:0032272,GO:0032502,GO:0032535,GO:0032553,GO:0032555,GO:0032559,GO:0032796,GO:0032956,GO:0032970,GO:0032982,GO:0032991,GO:0033036,GO:0033043,GO:0033275,GO:0033298,GO:0033554,GO:0034461,GO:0034622,GO:0035639,GO:0036094,GO:0040011,GO:0042221,GO:0042330,GO:0042493,GO:0042542,GO:0042594,GO:0042623,GO:0042641,GO:0042802,GO:0042803,GO:0042995,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043232,GO:0043254,GO:0043933,GO:0044085,GO:0044087,GO:0044422,GO:0044424,GO:0044425,GO:0044430,GO:0044444,GO:0044446,GO:0044448,GO:0044459,GO:0044464,GO:0044764,GO:0044877,GO:0045177,GO:0045179,GO:0045335,GO:0046677,GO:0046683,GO:0046847,GO:0046983,GO:0048519,GO:0048523,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051017,GO:0051128,GO:0051129,GO:0051179,GO:0051301,GO:0051493,GO:0051494,GO:0051591,GO:0051606,GO:0051674,GO:0051703,GO:0051704,GO:0051716,GO:0060327,GO:0060328,GO:0061572,GO:0061640,GO:0065003,GO:0065007,GO:0065008,GO:0070252,GO:0070938,GO:0071496,GO:0071840,GO:0071889,GO:0071944,GO:0090066,GO:0090702,GO:0097159,GO:0097204,GO:0097367,GO:0097435,GO:0097708,GO:0098630,GO:0098743,GO:0099120,GO:0099568,GO:0099738,GO:0110053,GO:0120025,GO:0120031,GO:0120036,GO:1901265,GO:1901363,GO:1901698,GO:1901700,GO:1902903,GO:1902904,GO:1903047,GO:1990753 - 0.000000000000006199 89.0
MMD2_k127_5266080_17 peptidase activity, acting on L-amino acid peptides K01179 - 3.2.1.4 0.0000000000001034 84.0
MMD2_k127_5266080_18 extracellular matrix structural constituent - - - 0.000001681 62.0
MMD2_k127_5266080_19 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.000002566 51.0
MMD2_k127_5266080_2 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000193 274.0
MMD2_k127_5266080_3 TIGR00268 family K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009946 248.0
MMD2_k127_5266080_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000007561 251.0
MMD2_k127_5266080_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000003556 215.0
MMD2_k127_5266080_6 PFAM zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000002767 216.0
MMD2_k127_5266080_7 CarboxypepD_reg-like domain - - - 0.00000000000000000000000000000000000000000000000000000000009951 232.0
MMD2_k127_5266080_8 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000008618 208.0
MMD2_k127_5266080_9 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000015 199.0
MMD2_k127_5275378_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1099.0
MMD2_k127_5275378_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 7.08e-197 623.0
MMD2_k127_5275378_10 cellulose binding - - - 0.0000000000000000000000001017 121.0
MMD2_k127_5275378_11 PFAM Cold-shock K03704 - - 0.0000000000000000004713 88.0
MMD2_k127_5275378_12 Fibronectin type III domain - - - 0.00000000000003343 83.0
MMD2_k127_5275378_13 Predicted periplasmic protein (DUF2271) - - - 0.0000000001785 74.0
MMD2_k127_5275378_14 LamG domain protein jellyroll fold domain protein K01190 - 3.2.1.23 0.000009979 57.0
MMD2_k127_5275378_15 Tetratricopeptide repeat - - - 0.00002164 57.0
MMD2_k127_5275378_16 extracellular matrix structural constituent - - - 0.00003625 55.0
MMD2_k127_5275378_17 - - - - 0.00008658 49.0
MMD2_k127_5275378_2 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 511.0
MMD2_k127_5275378_3 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 340.0
MMD2_k127_5275378_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 304.0
MMD2_k127_5275378_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003929 275.0
MMD2_k127_5275378_6 NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001284 267.0
MMD2_k127_5275378_7 Glycoside-hydrolase family GH114 K01884 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000003064 243.0
MMD2_k127_5275378_8 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000003296 203.0
MMD2_k127_5275378_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000001104 156.0
MMD2_k127_5327409_0 OPT oligopeptide transporter protein - - - 5.32e-229 727.0
MMD2_k127_5327409_1 PFAM ABC transporter related K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005143 431.0
MMD2_k127_5327409_10 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000002372 244.0
MMD2_k127_5327409_11 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000001232 259.0
MMD2_k127_5327409_12 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000002352 243.0
MMD2_k127_5327409_13 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000004563 217.0
MMD2_k127_5327409_14 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000719 216.0
MMD2_k127_5327409_15 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000001652 167.0
MMD2_k127_5327409_16 UbiA prenyltransferase family K03179,K17105 - 2.5.1.39,2.5.1.42 0.000000000000000000000000000000000001114 149.0
MMD2_k127_5327409_17 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000231 136.0
MMD2_k127_5327409_18 FMN binding K03809 - 1.6.5.2 0.00000000000000000000000000000000004638 150.0
MMD2_k127_5327409_19 HicB family - - - 0.000000000000000000000000000003557 126.0
MMD2_k127_5327409_2 NB-ARC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 436.0
MMD2_k127_5327409_20 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000008112 123.0
MMD2_k127_5327409_21 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000256 122.0
MMD2_k127_5327409_22 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000002534 109.0
MMD2_k127_5327409_23 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000003908 110.0
MMD2_k127_5327409_24 mitochondrial translation K02959 GO:0000028,GO:0000217,GO:0000400,GO:0003674,GO:0003676,GO:0003677,GO:0003735,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006259,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016787,GO:0016788,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000003918 94.0
MMD2_k127_5327409_25 Uncharacterised protein family UPF0102 K07460 - - 0.00000000000000000002847 94.0
MMD2_k127_5327409_26 Likely ribonuclease with RNase H fold. K07447 - - 0.00000000000000000003109 95.0
MMD2_k127_5327409_28 Cyclic nucleotide-monophosphate binding domain K10914 - - 0.00000000002103 78.0
MMD2_k127_5327409_29 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000002665 61.0
MMD2_k127_5327409_3 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 393.0
MMD2_k127_5327409_30 cellulose binding - - - 0.000004374 58.0
MMD2_k127_5327409_31 guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0001535 55.0
MMD2_k127_5327409_4 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 332.0
MMD2_k127_5327409_5 PFAM DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 299.0
MMD2_k127_5327409_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 297.0
MMD2_k127_5327409_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000104 302.0
MMD2_k127_5327409_8 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004667 279.0
MMD2_k127_5327409_9 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002536 272.0
MMD2_k127_5500689_0 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 372.0
MMD2_k127_5500689_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000007562 161.0
MMD2_k127_5541530_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 314.0
MMD2_k127_5541530_1 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000005195 185.0
MMD2_k127_5541530_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.00000000000000000000000000000000004401 145.0
MMD2_k127_5541530_3 nitroreductase K19286 - 1.5.1.39 0.00000000000000000000000000000001075 133.0
MMD2_k127_559335_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 553.0
MMD2_k127_559335_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 506.0
MMD2_k127_559335_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000006632 243.0
MMD2_k127_559335_3 - - - - 0.000000000000000002316 100.0
MMD2_k127_559335_4 Belongs to the peptidase S8 family - - - 0.00004842 56.0
MMD2_k127_5594964_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 580.0
MMD2_k127_5594964_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 503.0
MMD2_k127_5594964_10 Belongs to the ompA family - - - 0.00000000000000000000000000002029 136.0
MMD2_k127_5594964_11 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000005246 126.0
MMD2_k127_5594964_12 Diguanylate cyclase - - - 0.000000000000000000000000001267 132.0
MMD2_k127_5594964_13 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000009777 87.0
MMD2_k127_5594964_14 cyclic nucleotide binding K10914 - - 0.00000000000000002448 89.0
MMD2_k127_5594964_15 response to heat - - - 0.00000002322 58.0
MMD2_k127_5594964_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis - - - 0.0000002424 55.0
MMD2_k127_5594964_17 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00001748 56.0
MMD2_k127_5594964_2 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 442.0
MMD2_k127_5594964_3 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008743,GO:0009066,GO:0009987,GO:0016043,GO:0016491,GO:0016597,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0031406,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051287,GO:0051289,GO:0055114,GO:0065003,GO:0070403,GO:0071704,GO:0071840,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 396.0
MMD2_k127_5594964_4 ABC-2 type transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 295.0
MMD2_k127_5594964_5 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 292.0
MMD2_k127_5594964_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000127 252.0
MMD2_k127_5594964_7 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000008982 256.0
MMD2_k127_5594964_8 transcriptional activator domain - - - 0.000000000000000000000000000000000000004832 169.0
MMD2_k127_5594964_9 - - - - 0.00000000000000000000000000000001526 138.0
MMD2_k127_5787307_0 - - - - 0.00000000000000000000000007435 125.0
MMD2_k127_5787307_1 Belongs to the peptidase S8 family - - - 0.00000000000000000001181 97.0
MMD2_k127_5787307_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000003521 66.0
MMD2_k127_5787307_3 Belongs to the peptidase S8 family - - - 0.00004899 56.0
MMD2_k127_5796070_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 7.165e-208 670.0
MMD2_k127_5796070_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001389 244.0
MMD2_k127_5796070_2 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000005717 130.0
MMD2_k127_5821267_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 443.0
MMD2_k127_5821267_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 324.0
MMD2_k127_5821267_2 Polysaccharide export protein K01991 - - 0.0000000000000000000000000000000000009589 154.0
MMD2_k127_5821267_3 FMN binding - - - 0.00000000000000000000000000000001949 128.0
MMD2_k127_5821267_4 - - - - 0.000002986 50.0
MMD2_k127_5835341_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 361.0
MMD2_k127_5835341_1 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 325.0
MMD2_k127_5835341_10 Rossmann-like domain - - - 0.00000000000000000000006517 108.0
MMD2_k127_5835341_11 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000009645 111.0
MMD2_k127_5835341_12 S4 domain protein - - - 0.0000000000000008412 79.0
MMD2_k127_5835341_14 von Willebrand factor type A domain - - - 0.0000000004904 73.0
MMD2_k127_5835341_15 Domain of unknown function (DUF4388) - - - 0.00000007721 63.0
MMD2_k127_5835341_2 peptide catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 338.0
MMD2_k127_5835341_3 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 321.0
MMD2_k127_5835341_4 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005353 246.0
MMD2_k127_5835341_5 Bacterial sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000144 252.0
MMD2_k127_5835341_6 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000003031 200.0
MMD2_k127_5835341_7 - - - - 0.000000000000000000000000000000000000000000000000003542 188.0
MMD2_k127_5835341_8 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000004443 184.0
MMD2_k127_5835341_9 - - - - 0.00000000000000000000002425 116.0
MMD2_k127_5845628_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 512.0
MMD2_k127_5845628_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 445.0
MMD2_k127_5845628_10 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001325 257.0
MMD2_k127_5845628_11 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000007844 252.0
MMD2_k127_5845628_12 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000004691 221.0
MMD2_k127_5845628_13 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000106 163.0
MMD2_k127_5845628_14 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000001334 146.0
MMD2_k127_5845628_15 S23 ribosomal protein - - - 0.0000000000000000000000000000000003531 134.0
MMD2_k127_5845628_16 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000008615 119.0
MMD2_k127_5845628_17 export protein K01991 - - 0.000000000000000002275 95.0
MMD2_k127_5845628_18 Pfam:N_methyl_2 - - - 0.000000002836 66.0
MMD2_k127_5845628_19 Polysaccharide chain length determinant protein - - - 0.00000001096 68.0
MMD2_k127_5845628_2 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 452.0
MMD2_k127_5845628_20 Pfam:N_methyl_2 K02650 - - 0.00000006961 61.0
MMD2_k127_5845628_21 SurA N-terminal domain K03770 - 5.2.1.8 0.000002411 61.0
MMD2_k127_5845628_22 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0003529 53.0
MMD2_k127_5845628_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 424.0
MMD2_k127_5845628_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 422.0
MMD2_k127_5845628_5 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 414.0
MMD2_k127_5845628_6 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 385.0
MMD2_k127_5845628_7 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 327.0
MMD2_k127_5845628_8 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003772 286.0
MMD2_k127_5845628_9 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008981 271.0
MMD2_k127_5859083_0 Domain of unknown function (DUF1846) - - - 3.321e-247 771.0
MMD2_k127_5859083_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 421.0
MMD2_k127_5859083_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 379.0
MMD2_k127_5859083_3 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002623 239.0
MMD2_k127_5859083_4 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000001654 193.0
MMD2_k127_5859083_5 - - - - 0.00000000000000000001045 109.0
MMD2_k127_5859083_6 Hep Hag repeat protein - - - 0.0000000000000000002852 104.0
MMD2_k127_5859083_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000003231 76.0
MMD2_k127_5859083_8 ABC-2 family transporter protein K01992 - - 0.00000001771 64.0
MMD2_k127_5888233_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.612e-224 721.0
MMD2_k127_5888233_1 PFAM ApbE family K09740 - - 0.000000000000000000000000000008748 121.0
MMD2_k127_5888233_2 Tetratricopeptide repeat K19804 - - 0.00000000000000000000000000001084 132.0
MMD2_k127_5888233_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03749 - - 0.0001379 54.0
MMD2_k127_5983965_0 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 342.0
MMD2_k127_5983965_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 312.0
MMD2_k127_5983965_2 response regulator, receiver - - - 0.000000000000000000000000000000000000000000002698 172.0
MMD2_k127_5983965_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000009936 181.0
MMD2_k127_5983965_4 TIGRFAM diguanylate cyclase - - - 0.0000000000000000000000000001411 119.0
MMD2_k127_5983965_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000002486 108.0
MMD2_k127_5983965_6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000007346 55.0
MMD2_k127_5983965_7 Fibronectin type 3 domain - - - 0.00004969 53.0
MMD2_k127_5983965_8 FecR protein - - - 0.00007255 53.0
MMD2_k127_6068520_0 Glycoside hydrolase family 38 central region K01191 - 3.2.1.24 1.166e-316 1000.0
MMD2_k127_6068520_1 symporter activity K03307 - - 9.52e-214 685.0
MMD2_k127_6068520_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 393.0
MMD2_k127_6068520_11 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003816 409.0
MMD2_k127_6068520_12 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 398.0
MMD2_k127_6068520_13 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 373.0
MMD2_k127_6068520_14 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 372.0
MMD2_k127_6068520_15 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000952 357.0
MMD2_k127_6068520_16 aspartate dehydrogenase activity K03340 - 1.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 339.0
MMD2_k127_6068520_17 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 353.0
MMD2_k127_6068520_18 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 330.0
MMD2_k127_6068520_19 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918,K13799 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25,6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 304.0
MMD2_k127_6068520_2 Bacterial DNA topoisomeraes I ATP-binding domain K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006501 623.0
MMD2_k127_6068520_20 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004397 258.0
MMD2_k127_6068520_21 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000003791 258.0
MMD2_k127_6068520_22 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000002386 229.0
MMD2_k127_6068520_23 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.00000000000000000000000000000000000000000000000000000000001344 222.0
MMD2_k127_6068520_24 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.000000000000000000000000000000000000000000000000000000003817 208.0
MMD2_k127_6068520_25 lysyltransferase activity K07027,K20468 - - 0.0000000000000000000000000000000000000000000000000002782 196.0
MMD2_k127_6068520_26 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000002596 183.0
MMD2_k127_6068520_27 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000004097 182.0
MMD2_k127_6068520_28 Phage integrase, N-terminal SAM-like domain K14059 - - 0.000000000000000000000000000000000105 146.0
MMD2_k127_6068520_29 Putative RNA methylase family UPF0020 K02493 - 2.1.1.297 0.00000000000000000000000000000003147 138.0
MMD2_k127_6068520_3 PFAM aminotransferase class-III K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 531.0
MMD2_k127_6068520_30 cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000007868 132.0
MMD2_k127_6068520_31 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000002442 119.0
MMD2_k127_6068520_32 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.0000000000000000005937 94.0
MMD2_k127_6068520_33 Methyltransferase domain - - - 0.0000000000000002536 89.0
MMD2_k127_6068520_34 Helix-turn-helix XRE-family like proteins - - - 0.000000000000001653 77.0
MMD2_k127_6068520_35 DNA-binding protein PTS system, IIA component K02806 - - 0.000006379 50.0
MMD2_k127_6068520_36 penicillin-binding protein - - - 0.00001762 55.0
MMD2_k127_6068520_37 NYN domain - - - 0.00009551 44.0
MMD2_k127_6068520_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 526.0
MMD2_k127_6068520_5 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000212 484.0
MMD2_k127_6068520_6 aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 445.0
MMD2_k127_6068520_7 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 435.0
MMD2_k127_6068520_8 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 421.0
MMD2_k127_6068520_9 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 412.0
MMD2_k127_6090631_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 4.149e-297 932.0
MMD2_k127_6090631_1 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 410.0
MMD2_k127_6090631_10 PFAM Glucose Sorbosone dehydrogenase - - - 0.000346 52.0
MMD2_k127_6090631_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 362.0
MMD2_k127_6090631_3 lyase activity K01387,K03301 - 3.4.24.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 335.0
MMD2_k127_6090631_4 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004118 280.0
MMD2_k127_6090631_5 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000003869 226.0
MMD2_k127_6090631_6 TspO/MBR family K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000001528 178.0
MMD2_k127_6090631_7 MarR family - - - 0.00000000000000000000000000000001788 132.0
MMD2_k127_6090631_9 Disaggregatase related - - - 0.00000000000000000000004999 113.0
MMD2_k127_611982_0 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 488.0
MMD2_k127_611982_1 peptidase S9 prolyl oligopeptidase active site K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 487.0
MMD2_k127_611982_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006270,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032392,GO:0032508,GO:0033554,GO:0034641,GO:0034645,GO:0042623,GO:0043138,GO:0043140,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0046483,GO:0050896,GO:0051276,GO:0051716,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 458.0
MMD2_k127_611982_3 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 328.0
MMD2_k127_611982_4 by modhmm K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 305.0
MMD2_k127_611982_5 Transposase IS200 like K07491 - - 0.0000000000000000000000000003687 125.0
MMD2_k127_611982_6 Sigma-70, region 4 K03088 - - 0.0000000000000002596 85.0
MMD2_k127_6151154_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000389 514.0
MMD2_k127_6151154_1 peptidase activity, acting on L-amino acid peptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 487.0
MMD2_k127_6151154_2 Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 293.0
MMD2_k127_6151154_3 PFAM GAF domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000009272 150.0
MMD2_k127_6151154_4 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000003459 121.0
MMD2_k127_6151154_5 Rubrerythrin - - - 0.000000000000000009698 90.0
MMD2_k127_6151154_6 PFAM Desulfoferrodoxin ferrous iron-binding region K05919 - 1.15.1.2 0.000004639 51.0
MMD2_k127_6151154_7 guanyl-nucleotide exchange factor activity - - - 0.000006986 59.0
MMD2_k127_6180774_0 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 317.0
MMD2_k127_6180774_1 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000009081 230.0
MMD2_k127_6180774_10 - - - - 0.000000209 54.0
MMD2_k127_6180774_11 A domain in the BMP inhibitor chordin and in microbial proteins. - - - 0.0000008954 62.0
MMD2_k127_6180774_2 - - - - 0.000000000000000000000000000000000000000000000005114 179.0
MMD2_k127_6180774_3 - - - - 0.00000000000000000000000000000000000000000000008371 186.0
MMD2_k127_6180774_4 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000009862 186.0
MMD2_k127_6180774_5 Domain of unknown function (DUF4347) - - - 0.000000000000000000000000000000000000000000006728 187.0
MMD2_k127_6180774_7 PFAM MazG nucleotide pyrophosphohydrolase - - - 0.00000000000000000000000000003833 118.0
MMD2_k127_6180774_8 Peptidase_C39 like family - - - 0.000000000006387 79.0
MMD2_k127_6180774_9 S23 ribosomal protein - - - 0.0000000004633 66.0
MMD2_k127_6191129_0 serine-type peptidase activity K04773 - - 6.87e-201 652.0
MMD2_k127_6191129_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 504.0
MMD2_k127_6191129_10 Fibronectin type 3 domain - - - 0.00000000005308 77.0
MMD2_k127_6191129_11 CoA transferase having broad substrate specificity for short-chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons K01026 - 2.8.3.1 0.0002089 49.0
MMD2_k127_6191129_2 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 389.0
MMD2_k127_6191129_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009401 357.0
MMD2_k127_6191129_4 COGs COG0265 Trypsin-like serine protease typically periplasmic contain C-terminal PDZ domain K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 361.0
MMD2_k127_6191129_5 by modhmm K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003901 291.0
MMD2_k127_6191129_6 Belongs to the peptidase S8 family K08651,K13274,K13276,K13277 - 3.4.21.66 0.00000000000000000000000000000000000000000001139 187.0
MMD2_k127_6191129_7 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000005906 139.0
MMD2_k127_6191129_8 Copper amine oxidase N-terminal domain - - - 0.00000000000000000000000001349 115.0
MMD2_k127_6191129_9 WD40-like Beta Propeller Repeat K03641,K08676 - - 0.0000000000000000000005084 108.0
MMD2_k127_6199610_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 366.0
MMD2_k127_6199610_1 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 352.0
MMD2_k127_6199610_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000007046 261.0
MMD2_k127_6199610_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000004294 228.0
MMD2_k127_6199610_4 Transglycosylase SLT domain - - - 0.000000000000000000000000000000001284 136.0
MMD2_k127_6199610_5 PFAM Pectate lyase - - - 0.0000000002256 72.0
MMD2_k127_6199610_6 Transposase IS200 like K07491 - - 0.0000005089 58.0
MMD2_k127_621032_0 4Fe-4S binding domain K02572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 359.0
MMD2_k127_621032_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002941 275.0
MMD2_k127_621032_10 Motility related/secretion protein - - - 0.000004738 61.0
MMD2_k127_621032_2 Type II and III secretion system protein K02666 - - 0.000000000000000000000000000000000000000000000000000000000204 223.0
MMD2_k127_621032_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000001595 181.0
MMD2_k127_621032_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000004436 183.0
MMD2_k127_621032_5 RNA methyltransferase, RsmD family - - - 0.000000000000000000000000000000004378 136.0
MMD2_k127_621032_6 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000001158 99.0
MMD2_k127_621032_7 Pilus assembly protein, PilO K02664 - - 0.000000000000000000814 91.0
MMD2_k127_621032_9 Pilus assembly protein, PilP K02665 - - 0.0000000003881 66.0
MMD2_k127_6221608_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.444e-286 899.0
MMD2_k127_6221608_1 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 5.289e-260 814.0
MMD2_k127_6221608_10 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.000000000000000000000000003207 116.0
MMD2_k127_6221608_11 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.0000000000000000000000007866 109.0
MMD2_k127_6221608_12 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0000000000000000000002366 102.0
MMD2_k127_6221608_13 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000009382 71.0
MMD2_k127_6221608_14 - - - - 0.000000002298 64.0
MMD2_k127_6221608_15 Hsp20/alpha crystallin family K13993 - - 0.000000006735 63.0
MMD2_k127_6221608_2 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 569.0
MMD2_k127_6221608_3 Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009724 423.0
MMD2_k127_6221608_4 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 360.0
MMD2_k127_6221608_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005718 270.0
MMD2_k127_6221608_6 transport, permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000293 251.0
MMD2_k127_6221608_7 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000008035 216.0
MMD2_k127_6221608_8 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000003217 198.0
MMD2_k127_6221608_9 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000001038 139.0
MMD2_k127_6258295_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000268 533.0
MMD2_k127_6258295_1 CAAX protease self-immunity K07052 - - 0.000000000000000000005456 101.0
MMD2_k127_6258295_2 Tetratricopeptide repeat - - - 0.000000000002834 76.0
MMD2_k127_6258295_3 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000002525 68.0
MMD2_k127_6258295_4 peptidyl-tyrosine sulfation - - - 0.000002579 58.0
MMD2_k127_6258295_5 Permeases of the major facilitator superfamily - - - 0.00002304 55.0
MMD2_k127_6266143_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.171e-256 806.0
MMD2_k127_6266143_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 2.337e-201 644.0
MMD2_k127_6266143_10 PFAM GPR1 FUN34 yaaH family K07034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001792 272.0
MMD2_k127_6266143_11 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000007417 271.0
MMD2_k127_6266143_12 UbiE COQ5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001222 268.0
MMD2_k127_6266143_13 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001129 263.0
MMD2_k127_6266143_14 Belongs to the FPP GGPP synthase family K13789 GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0071704,GO:1901576 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000007474 241.0
MMD2_k127_6266143_15 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004721 246.0
MMD2_k127_6266143_16 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007604 244.0
MMD2_k127_6266143_17 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000003615 235.0
MMD2_k127_6266143_18 cobalamin binding - - - 0.0000000000000000000000000000000000000000000000000000000144 204.0
MMD2_k127_6266143_19 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000001225 201.0
MMD2_k127_6266143_2 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004288 526.0
MMD2_k127_6266143_20 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000003046 195.0
MMD2_k127_6266143_21 Peptidase M28 - - - 0.0000000000000000000000000000000000000000007695 168.0
MMD2_k127_6266143_22 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000005039 109.0
MMD2_k127_6266143_23 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000000000000006094 101.0
MMD2_k127_6266143_24 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.00000000000000009966 92.0
MMD2_k127_6266143_25 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000004314 86.0
MMD2_k127_6266143_26 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000000000009004 91.0
MMD2_k127_6266143_27 TIGRFAM competence protein ComEA helix-hairpin-helix K02237 - - 0.0000000000001011 80.0
MMD2_k127_6266143_28 virulence factor Mce family protein K02067 - - 0.0000000000004128 79.0
MMD2_k127_6266143_29 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000003778 56.0
MMD2_k127_6266143_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 464.0
MMD2_k127_6266143_30 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000035 63.0
MMD2_k127_6266143_31 cellulose binding - - - 0.0002163 54.0
MMD2_k127_6266143_32 Two component regulator propeller - - - 0.000525 51.0
MMD2_k127_6266143_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000326 413.0
MMD2_k127_6266143_5 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 411.0
MMD2_k127_6266143_6 GcpE protein K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 379.0
MMD2_k127_6266143_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 370.0
MMD2_k127_6266143_8 methyltransferase K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 384.0
MMD2_k127_6266143_9 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 297.0
MMD2_k127_657128_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 520.0
MMD2_k127_657128_1 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 511.0
MMD2_k127_657128_10 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000006094 178.0
MMD2_k127_657128_11 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000009207 179.0
MMD2_k127_657128_12 PFAM Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000003994 147.0
MMD2_k127_657128_13 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000004502 135.0
MMD2_k127_657128_14 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000003465 127.0
MMD2_k127_657128_15 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000001764 97.0
MMD2_k127_657128_16 acr, cog1399 K07040 - - 0.000000000000000004111 92.0
MMD2_k127_657128_17 Protein of unknown function (DUF541) - - - 0.00009412 53.0
MMD2_k127_657128_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006339 411.0
MMD2_k127_657128_3 Required for chromosome condensation and partitioning K03529,K19171 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 389.0
MMD2_k127_657128_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 353.0
MMD2_k127_657128_5 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005228 276.0
MMD2_k127_657128_6 COGs COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000001528 270.0
MMD2_k127_657128_7 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001567 259.0
MMD2_k127_657128_8 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001267 255.0
MMD2_k127_657128_9 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000701 257.0
MMD2_k127_723311_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 0.0 1199.0
MMD2_k127_723311_1 Nucleotidyl transferase K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 451.0
MMD2_k127_723311_10 Hep Hag repeat protein K21449 - - 0.00000000000000000000000002718 127.0
MMD2_k127_723311_11 Belongs to the peptidase S8 family - - - 0.000000000000000000000001447 119.0
MMD2_k127_723311_12 Transposase IS200 like - - - 0.0000000000000000000001592 102.0
MMD2_k127_723311_13 -acetyltransferase K03826,K03827 - - 0.000000000000000000007041 98.0
MMD2_k127_723311_14 - - - - 0.0000000000000000001464 89.0
MMD2_k127_723311_15 Hep Hag repeat protein K01406,K21449 - 3.4.24.40 0.000000000000000001275 102.0
MMD2_k127_723311_16 Hep Hag repeat protein - - - 0.0000000000000002767 94.0
MMD2_k127_723311_18 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000004443 91.0
MMD2_k127_723311_19 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000000007149 81.0
MMD2_k127_723311_2 nucleic acid phosphodiester bond hydrolysis K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 448.0
MMD2_k127_723311_20 - - - - 0.00000000000001605 76.0
MMD2_k127_723311_21 - - - - 0.0000001453 53.0
MMD2_k127_723311_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 386.0
MMD2_k127_723311_4 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975,K20427 - 2.7.7.27,2.7.7.91 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 352.0
MMD2_k127_723311_5 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 312.0
MMD2_k127_723311_6 Cation efflux family - - - 0.00000000000000000000000000000000000000000000000000000000000000001194 230.0
MMD2_k127_723311_7 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000001795 188.0
MMD2_k127_723311_8 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - 0.00000000000000000000000000000000000000005705 176.0
MMD2_k127_723311_9 - - - - 0.00000000000000000000000000000002489 147.0
MMD2_k127_785004_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 348.0
MMD2_k127_785004_1 PFAM Mg2 transporter protein CorA family protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
MMD2_k127_785004_10 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000003874 139.0
MMD2_k127_785004_11 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000564 134.0
MMD2_k127_785004_12 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003448 136.0
MMD2_k127_785004_13 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000005067 98.0
MMD2_k127_785004_14 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000818 94.0
MMD2_k127_785004_15 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000001121 102.0
MMD2_k127_785004_16 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000009463 88.0
MMD2_k127_785004_17 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000003999 90.0
MMD2_k127_785004_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000002591 88.0
MMD2_k127_785004_19 Ribosomal L29 protein K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000001173 62.0
MMD2_k127_785004_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0000028,GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000004536 252.0
MMD2_k127_785004_3 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000006756 224.0
MMD2_k127_785004_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000001055 216.0
MMD2_k127_785004_5 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000007406 213.0
MMD2_k127_785004_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001177 198.0
MMD2_k127_785004_7 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000001002 188.0
MMD2_k127_785004_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0008150,GO:0015934,GO:0016020,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071944,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000001542 177.0
MMD2_k127_785004_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000008922 169.0
MMD2_k127_803295_0 PFAM Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000003351 127.0
MMD2_k127_803295_1 - - - - 0.000000000000000000000000002614 124.0
MMD2_k127_803897_0 MutL protein K00854 - 2.7.1.17 1.047e-256 803.0
MMD2_k127_803897_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003746 575.0
MMD2_k127_803897_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 287.0
MMD2_k127_803897_12 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000806 283.0
MMD2_k127_803897_13 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004382 285.0
MMD2_k127_803897_14 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000382 256.0
MMD2_k127_803897_16 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002551 254.0
MMD2_k127_803897_17 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000004646 251.0
MMD2_k127_803897_18 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000008025 255.0
MMD2_k127_803897_19 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000001642 215.0
MMD2_k127_803897_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030312,GO:0030554,GO:0031333,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0044087,GO:0044238,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000778 481.0
MMD2_k127_803897_20 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000001956 220.0
MMD2_k127_803897_21 - - - - 0.000000000000000000000000000000000000000000000000000005068 200.0
MMD2_k127_803897_22 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000008408 201.0
MMD2_k127_803897_23 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000002124 182.0
MMD2_k127_803897_24 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000003358 179.0
MMD2_k127_803897_25 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000005058 164.0
MMD2_k127_803897_26 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000266 155.0
MMD2_k127_803897_27 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.00000000000000000000000000000003291 130.0
MMD2_k127_803897_28 peptidase M23 - - - 0.00000000000000000000000000001771 132.0
MMD2_k127_803897_29 - - - - 0.000000000000000000000000008871 122.0
MMD2_k127_803897_3 PglZ domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006924 421.0
MMD2_k127_803897_30 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000002771 109.0
MMD2_k127_803897_31 - - - - 0.000000000000000000000005375 107.0
MMD2_k127_803897_32 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000004145 95.0
MMD2_k127_803897_33 Cold shock protein K03704 - - 0.0000000000000000008978 89.0
MMD2_k127_803897_34 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000001978 81.0
MMD2_k127_803897_35 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000729 75.0
MMD2_k127_803897_36 - - - - 0.000000000002967 75.0
MMD2_k127_803897_37 PTS system fructose IIA component K02744 - - 0.000000000008497 76.0
MMD2_k127_803897_38 FlgD Ig-like domain - - - 0.000000003735 70.0
MMD2_k127_803897_39 YbbR-like protein - - - 0.00000007246 63.0
MMD2_k127_803897_4 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 415.0
MMD2_k127_803897_40 Putative zinc-finger - - - 0.0003677 49.0
MMD2_k127_803897_5 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 399.0
MMD2_k127_803897_6 radical SAM domain protein K06139 GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0018130,GO:0018189,GO:0018193,GO:0018212,GO:0019538,GO:0019752,GO:0034641,GO:0036211,GO:0042180,GO:0042181,GO:0042364,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072350,GO:0072351,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901661,GO:1901663 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 390.0
MMD2_k127_803897_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 346.0
MMD2_k127_803897_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 353.0
MMD2_k127_803897_9 PKD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 323.0
MMD2_k127_823426_0 Heat shock 70 kDa protein K04043 - - 1.853e-254 799.0
MMD2_k127_823426_1 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.119e-203 646.0
MMD2_k127_823426_10 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000005943 139.0
MMD2_k127_823426_11 Nitroreductase family - - - 0.00000000000000000000000000000312 127.0
MMD2_k127_823426_12 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000005055 126.0
MMD2_k127_823426_13 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000002834 112.0
MMD2_k127_823426_14 Part of a membrane complex involved in electron transport K03617 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000009269 115.0
MMD2_k127_823426_15 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000005317 99.0
MMD2_k127_823426_16 GTP-binding protein HSR1-related K06944 - - 0.0000000000000002021 80.0
MMD2_k127_823426_17 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000001055 83.0
MMD2_k127_823426_18 Tetratricopeptide repeat - - - 0.000000000001358 80.0
MMD2_k127_823426_19 Membrane protein involved in the export of O-antigen and teichoic acid K03328 - - 0.0000003473 63.0
MMD2_k127_823426_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 511.0
MMD2_k127_823426_20 - - - - 0.0005279 53.0
MMD2_k127_823426_3 Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 339.0
MMD2_k127_823426_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002613 286.0
MMD2_k127_823426_5 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002399 283.0
MMD2_k127_823426_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000001672 206.0
MMD2_k127_823426_7 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000003673 217.0
MMD2_k127_823426_8 PFAM Uncharacterised BCR, COG1649 - - - 0.00000000000000000000000000000000000000001248 167.0
MMD2_k127_823426_9 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070042,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.193 0.000000000000000000000000000000000003681 146.0
MMD2_k127_938388_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1365.0
MMD2_k127_938388_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1046.0
MMD2_k127_938388_2 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 376.0
MMD2_k127_986469_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 452.0
MMD2_k127_986469_1 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004155 410.0
MMD2_k127_986469_10 Involved in DNA repair and RecF pathway recombination K03584 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000445 117.0
MMD2_k127_986469_11 long-chain fatty acid transport protein - - - 0.0000000000000003167 90.0
MMD2_k127_986469_12 COG3103 SH3 domain protein K01448 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.5.1.28 0.0000000000001768 84.0
MMD2_k127_986469_13 - - - - 0.0000000000508 76.0
MMD2_k127_986469_2 Tryptophanyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 378.0
MMD2_k127_986469_3 Zn-dependent proteases and their inactivated homologs K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 366.0
MMD2_k127_986469_4 agmatine deiminase activity K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000001473 272.0
MMD2_k127_986469_5 NmrA-like family K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000001425 213.0
MMD2_k127_986469_6 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000002497 205.0
MMD2_k127_986469_7 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000002678 184.0
MMD2_k127_986469_8 Glyco_18 K01448,K07260,K20276 - 3.4.17.14,3.5.1.28 0.000000000000000000000000000000000000000000005823 186.0
MMD2_k127_986469_9 Transcription termination factor nusG - - - 0.00000000000000000000000000001081 124.0
MMD2_k127_990928_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 2.153e-208 661.0
MMD2_k127_990928_1 Belongs to the rhamnose isomerase family K01813 - 5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 443.0
MMD2_k127_990928_10 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000001041 220.0
MMD2_k127_990928_11 Belongs to the glycosyl hydrolase 2 family - - - 0.00000000000000000000000000000000000000000000000000000005114 218.0
MMD2_k127_990928_12 PFAM Isochorismatase - - - 0.00000000000000000000000000000000000000000000000000000009002 202.0
MMD2_k127_990928_13 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000002026 196.0
MMD2_k127_990928_14 Peptidase, M23 - - - 0.0000000000000000000000003072 115.0
MMD2_k127_990928_15 Lipopolysaccharide-assembly - - - 0.00000001123 67.0
MMD2_k127_990928_16 Outer membrane lipoprotein - - - 0.0000001822 64.0
MMD2_k127_990928_17 synthase - - - 0.0000002744 63.0
MMD2_k127_990928_2 Polysaccharide biosynthesis protein K15856 - 1.1.1.281 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 432.0
MMD2_k127_990928_20 metallopeptidase activity - - - 0.0008155 51.0
MMD2_k127_990928_3 Psort location Cytoplasmic, score K00848,K00879 - 2.7.1.5,2.7.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 446.0
MMD2_k127_990928_4 PFAM Radical SAM domain protein K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 383.0
MMD2_k127_990928_5 peptidase M42 family protein K01179 - 3.2.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 327.0
MMD2_k127_990928_6 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 294.0
MMD2_k127_990928_7 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004531 288.0
MMD2_k127_990928_8 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004436 264.0
MMD2_k127_990928_9 PFAM Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000005295 251.0