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Overview

ID MAG02361
Name MMD2_bin.21
Sample SMP0059
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order 40CM-2-53-6
Family RBG-13-38-9
Genus JAPKYM01
Species
Assembly information
Completeness (%) 84.58
Contamination (%) 1.6
GC content (%) 48.0
N50 (bp) 6,582
Genome size (bp) 1,054,685

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1039

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1010798_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 539.0
MMD2_k127_1010798_1 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 413.0
MMD2_k127_1010798_10 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000006226 83.0
MMD2_k127_1010798_11 transcriptional K03719 - - 0.000000000000437 76.0
MMD2_k127_1010798_12 - - - - 0.000000000001379 77.0
MMD2_k127_1010798_13 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000004183 69.0
MMD2_k127_1010798_14 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000003769 61.0
MMD2_k127_1010798_15 Chromatin associated protein KTI12 K00860 - 2.7.1.25 0.0000006805 52.0
MMD2_k127_1010798_2 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 409.0
MMD2_k127_1010798_3 Mn2 dependent serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003368 259.0
MMD2_k127_1010798_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000002557 178.0
MMD2_k127_1010798_5 Conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000000002483 158.0
MMD2_k127_1010798_6 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000003511 147.0
MMD2_k127_1010798_7 Conserved protein implicated in secretion - - - 0.0000000000000000000000000000000004757 141.0
MMD2_k127_1010798_8 Conserved protein implicated in secretion - - - 0.00000000000000000000000001301 119.0
MMD2_k127_1010798_9 - - - - 0.0000000000000000005756 94.0
MMD2_k127_1031757_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 487.0
MMD2_k127_1031757_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000727 284.0
MMD2_k127_1031757_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000002447 172.0
MMD2_k127_1031757_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.000000000000000000000003594 108.0
MMD2_k127_1031757_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000538 94.0
MMD2_k127_1031757_5 MoaE protein K03635 - 2.8.1.12 0.00000000000000000001928 98.0
MMD2_k127_1031757_6 Belongs to the peptidase S8 family - - - 0.00000000007411 75.0
MMD2_k127_1065764_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003186 283.0
MMD2_k127_1065764_1 nicotinamide-nucleotide adenylyltransferase K00952 - 2.7.7.1 0.00000000000000000000000000000000000000000000000000105 188.0
MMD2_k127_1065764_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000001028 118.0
MMD2_k127_1065764_3 COG0350 Methylated DNA-protein cysteine methyltransferase K00567 - 2.1.1.63 0.00000000000001601 81.0
MMD2_k127_1065764_4 Belongs to the UPF0248 family K09715 - - 0.0000000001102 65.0
MMD2_k127_1072470_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000001343 214.0
MMD2_k127_1072470_1 cobalamin binding K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000149 180.0
MMD2_k127_1072470_2 PFAM CoA-binding domain protein K06929 - - 0.00000000000000000000000000000000000000003944 156.0
MMD2_k127_1072470_3 - - - - 0.00000000000000000000000000000000000000009616 158.0
MMD2_k127_108196_0 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 479.0
MMD2_k127_108196_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000002292 245.0
MMD2_k127_1102230_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 472.0
MMD2_k127_1102230_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 412.0
MMD2_k127_1102230_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001458 283.0
MMD2_k127_1102230_3 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008186 274.0
MMD2_k127_1102230_4 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000006127 267.0
MMD2_k127_1102230_5 SMART Elongator protein 3 MiaB NifB K22226 - - 0.0000000000000000000000000000000000001251 145.0
MMD2_k127_1102230_6 transcriptional regulator, AsnC family - - - 0.00000000000000000000000000000000004305 139.0
MMD2_k127_1102230_7 synthase K01719 - 4.2.1.75 0.00000000000000000000000000009505 130.0
MMD2_k127_1102230_8 SMART Transcription regulator, AsnC-type - - - 0.000000000000000000000000000172 130.0
MMD2_k127_1148657_0 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000006366 248.0
MMD2_k127_1148657_1 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.00000000000000000000000000000000000007595 146.0
MMD2_k127_1148657_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000003735 134.0
MMD2_k127_1148657_3 nitrate reductase activity - - - 0.000000003721 66.0
MMD2_k127_1178606_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000004801 259.0
MMD2_k127_1178606_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000000000000000000000000000000001022 193.0
MMD2_k127_1178606_2 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000000796 184.0
MMD2_k127_1178606_3 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000004775 184.0
MMD2_k127_1178606_4 RNA polymerase subunit 9 K03057 - - 0.00000000000000000000000002597 111.0
MMD2_k127_1178606_5 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000001443 93.0
MMD2_k127_1178606_6 Ribonuclease III - - - 0.00000000000000001977 87.0
MMD2_k127_1178606_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000002167 68.0
MMD2_k127_120983_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 475.0
MMD2_k127_120983_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000001072 264.0
MMD2_k127_120983_2 HMGL-like K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000003209 263.0
MMD2_k127_120983_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000001322 229.0
MMD2_k127_120983_4 methylase K07446 - 2.1.1.213 0.0000000000000000000000000000000000000000000000000008522 197.0
MMD2_k127_120983_5 pfam rdd - - - 0.0000000000000000003143 93.0
MMD2_k127_120983_6 Belongs to the UPF0201 family K09736 - - 0.000000006584 59.0
MMD2_k127_1225883_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008825 537.0
MMD2_k127_1225883_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 409.0
MMD2_k127_1225883_2 TIGRFAM LPPG domain protein containing protein K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 329.0
MMD2_k127_1225883_4 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0043814,GO:0044237,GO:0044249,GO:0051186,GO:0051188,GO:0070568 2.7.7.68 0.00000000000000000000000008702 114.0
MMD2_k127_1226794_0 Glutamate synthase - - - 7.06e-231 725.0
MMD2_k127_1226794_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000008215 101.0
MMD2_k127_1286475_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000001127 233.0
MMD2_k127_1286475_1 protein possibly involved in utilization of glycolate and propanediol - - - 0.000000000000000000000000000000000000000000001065 169.0
MMD2_k127_1286475_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000002247 159.0
MMD2_k127_1286475_3 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000216 150.0
MMD2_k127_1286475_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000009582 115.0
MMD2_k127_1286475_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000001723 109.0
MMD2_k127_1286475_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000001214 106.0
MMD2_k127_1286475_7 - - - - 0.000000000008144 71.0
MMD2_k127_1309146_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003555 565.0
MMD2_k127_1309146_1 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 367.0
MMD2_k127_1309146_10 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000003478 163.0
MMD2_k127_1309146_11 AsnC family - - - 0.000000006327 59.0
MMD2_k127_1309146_12 Lrp/AsnC ligand binding domain - - - 0.00001083 51.0
MMD2_k127_1309146_2 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002067 337.0
MMD2_k127_1309146_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 338.0
MMD2_k127_1309146_4 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 302.0
MMD2_k127_1309146_5 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000005864 250.0
MMD2_k127_1309146_6 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000004562 243.0
MMD2_k127_1309146_7 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.00000000000000000000000000000000000000000000000000001628 200.0
MMD2_k127_1309146_8 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000117 197.0
MMD2_k127_1309146_9 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036220,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000000001312 178.0
MMD2_k127_1366237_0 SAF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 316.0
MMD2_k127_1366237_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000005934 237.0
MMD2_k127_1366237_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000001132 162.0
MMD2_k127_1366237_3 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000003706 151.0
MMD2_k127_1366237_4 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.00000000000000000000000000308 116.0
MMD2_k127_1366237_5 deoxyribonuclease V activity K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.00000000001037 68.0
MMD2_k127_1366237_6 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.0000000001309 65.0
MMD2_k127_1379884_0 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 416.0
MMD2_k127_1379884_1 transferase activity, transferring glycosyl groups K13693,K21349 - 2.4.1.266,2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 314.0
MMD2_k127_1379884_2 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000003943 184.0
MMD2_k127_1379884_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000001106 153.0
MMD2_k127_1425931_0 AIR synthase related protein, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
MMD2_k127_1425931_1 Belongs to the UPF0282 family K07022 - - 0.000000000000000000000000000000000000000000000000000000000004692 220.0
MMD2_k127_1425931_2 - - - - 0.00000000086 66.0
MMD2_k127_1425931_3 PFAM Glycosyl transferase, group 1 - - - 0.00005007 50.0
MMD2_k127_1425931_4 Glycosyltransferase like family 2 - - - 0.0001903 52.0
MMD2_k127_1433170_0 PFAM ATP dependent DNA ligase K01971,K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000005345 265.0
MMD2_k127_1433170_1 Saccharopine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000008792 246.0
MMD2_k127_1433170_2 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000003698 216.0
MMD2_k127_1433170_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000008569 104.0
MMD2_k127_1433170_4 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD - - - 0.00004682 47.0
MMD2_k127_143799_0 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000001798 156.0
MMD2_k127_143799_1 PFAM Molybdopterin guanine dinucleotide synthesis protein B K06947 - - 0.000000000000000000000000000000000000552 152.0
MMD2_k127_143799_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000008833 144.0
MMD2_k127_143799_3 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000003695 142.0
MMD2_k127_143799_4 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000001301 121.0
MMD2_k127_143799_5 MazG-like family - - - 0.000000000000000000000001081 108.0
MMD2_k127_143799_6 - - - - 0.00000000000003306 78.0
MMD2_k127_1514340_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 288.0
MMD2_k127_1514340_1 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000001047 153.0
MMD2_k127_1514340_2 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001643 109.0
MMD2_k127_1514340_3 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000653 94.0
MMD2_k127_1514340_4 Methionine biosynthesis protein MetW - - - 0.00000001409 63.0
MMD2_k127_1660618_0 TIGRFAM dihydropteroate synthase-related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004379 308.0
MMD2_k127_1660618_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.00000000000000000000000000000000000000000000000000000000000000005958 230.0
MMD2_k127_1660618_2 - - - - 0.0008862 50.0
MMD2_k127_1711934_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 4.905e-216 687.0
MMD2_k127_1711934_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 532.0
MMD2_k127_1711934_2 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 376.0
MMD2_k127_1711934_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.000000000000000000000000000001161 128.0
MMD2_k127_1711934_4 ribosomal protein K02976 - - 0.00000000000000000000000000003027 118.0
MMD2_k127_1711934_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000003213 89.0
MMD2_k127_1711934_6 - - - - 0.00000000005293 64.0
MMD2_k127_1711934_7 HTH DNA binding domain - - - 0.0004455 46.0
MMD2_k127_1740899_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 390.0
MMD2_k127_1740899_1 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 364.0
MMD2_k127_1740899_10 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000003598 102.0
MMD2_k127_1740899_11 HAD-hyrolase-like K01560,K07025,K08723 - 3.1.3.5,3.8.1.2 0.000000000000002797 85.0
MMD2_k127_1740899_12 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.0000000000003898 74.0
MMD2_k127_1740899_13 KEOPS complex Cgi121-like subunit K09119 - - 0.000000003289 65.0
MMD2_k127_1740899_14 protein, 4-oxalocrotonate tautomerase homolog K01821 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0044237 5.3.2.6 0.00000001144 58.0
MMD2_k127_1740899_15 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.00000005072 57.0
MMD2_k127_1740899_16 TIGRFAM MoaD family protein K03636 - - 0.00000005856 57.0
MMD2_k127_1740899_17 Belongs to the eukaryotic ribosomal protein eL38 family K02923 - - 0.000002557 51.0
MMD2_k127_1740899_18 - - - - 0.00002726 49.0
MMD2_k127_1740899_19 subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors K04505 - - 0.00003861 55.0
MMD2_k127_1740899_2 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 GO:0000054,GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005506,GO:0005524,GO:0006403,GO:0006405,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006611,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0008104,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015931,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0022613,GO:0030554,GO:0031503,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0033036,GO:0033750,GO:0034613,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042254,GO:0042886,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0045184,GO:0046872,GO:0046907,GO:0046914,GO:0050657,GO:0050658,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051236,GO:0051640,GO:0051641,GO:0051649,GO:0051656,GO:0070727,GO:0071166,GO:0071426,GO:0071428,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000006577 257.0
MMD2_k127_1740899_3 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000003948 166.0
MMD2_k127_1740899_4 PFAM THUMP domain protein K06963 - - 0.00000000000000000000000000000000000004944 149.0
MMD2_k127_1740899_5 PAC2 family K07159 - - 0.00000000000000000000000000000000002296 144.0
MMD2_k127_1740899_6 molybdopterin binding domain - - - 0.00000000000000000000000000000002791 136.0
MMD2_k127_1740899_7 PFAM PAC2 family K06869 - - 0.0000000000000000000000000000001321 133.0
MMD2_k127_1740899_8 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000000004843 115.0
MMD2_k127_1740899_9 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000009695 119.0
MMD2_k127_1785246_0 Belongs to the carbamoyltransferase HypF family K04656 - - 1.152e-204 661.0
MMD2_k127_1785246_1 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000495 126.0
MMD2_k127_1785246_2 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000000000002805 94.0
MMD2_k127_1785246_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000008325 70.0
MMD2_k127_1830476_0 argininosuccinate lyase K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 385.0
MMD2_k127_1830476_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 0.000000000000000000000000000000000005765 147.0
MMD2_k127_1830476_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000002619 93.0
MMD2_k127_1946785_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 409.0
MMD2_k127_1946785_1 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005884 251.0
MMD2_k127_1946785_2 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000006733 218.0
MMD2_k127_1946785_3 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000002661 199.0
MMD2_k127_1946785_4 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000001232 145.0
MMD2_k127_1946785_5 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.000000000000000004262 85.0
MMD2_k127_196726_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 578.0
MMD2_k127_196726_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 555.0
MMD2_k127_196726_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 344.0
MMD2_k127_196726_11 Lysine biosynthesis K05827 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 313.0
MMD2_k127_196726_12 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 297.0
MMD2_k127_196726_13 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 290.0
MMD2_k127_196726_14 Lysine biosynthesis K05827 - 6.3.2.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003552 291.0
MMD2_k127_196726_15 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005744 285.0
MMD2_k127_196726_16 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007025 280.0
MMD2_k127_196726_17 Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
MMD2_k127_196726_18 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000002068 228.0
MMD2_k127_196726_19 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000001089 209.0
MMD2_k127_196726_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 517.0
MMD2_k127_196726_20 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000003834 206.0
MMD2_k127_196726_21 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000002157 198.0
MMD2_k127_196726_22 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000001078 188.0
MMD2_k127_196726_23 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000004391 186.0
MMD2_k127_196726_24 Psort location Cytoplasmic, score K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000002362 177.0
MMD2_k127_196726_25 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000383 147.0
MMD2_k127_196726_26 structural constituent of ribosome K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000285 105.0
MMD2_k127_196726_27 hydrolase - - - 0.000000000000000000194 102.0
MMD2_k127_196726_28 lysine biosynthesis protein LysW K05826 - - 0.000000000000001316 78.0
MMD2_k127_196726_29 lysine biosynthesis protein LysW K05826 - - 0.000000003588 59.0
MMD2_k127_196726_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 488.0
MMD2_k127_196726_4 Homocitrate synthase K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000681 487.0
MMD2_k127_196726_5 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 444.0
MMD2_k127_196726_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 431.0
MMD2_k127_196726_7 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 416.0
MMD2_k127_196726_8 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 393.0
MMD2_k127_196726_9 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 394.0
MMD2_k127_2136766_0 COG0467 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.00000000000000000000000000000000001933 143.0
MMD2_k127_2136766_1 cheY-homologous receiver domain - - - 0.0000000000000000000000001735 113.0
MMD2_k127_2136766_2 Circadian clock protein KaiC - - - 0.00000000000002747 78.0
MMD2_k127_214083_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000579 224.0
MMD2_k127_214083_1 COG1522 Transcriptional regulators K03718 - - 0.0000000000000000000000000007918 122.0
MMD2_k127_214083_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000004784 106.0
MMD2_k127_214083_3 Thymidylate kinase - - - 0.00000006093 64.0
MMD2_k127_2151437_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 8.699e-301 945.0
MMD2_k127_2151437_1 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 589.0
MMD2_k127_2151437_2 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 400.0
MMD2_k127_2151437_3 SAICAR synthetase K01923 - 6.3.2.6 0.000003529 51.0
MMD2_k127_2159481_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003073 251.0
MMD2_k127_2159481_1 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000001141 181.0
MMD2_k127_2159481_2 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000000000000003713 140.0
MMD2_k127_2217542_0 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000008197 155.0
MMD2_k127_2224924_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009165 372.0
MMD2_k127_2224924_1 Probably catalyzes the hydrolysis of L-ascorbate-6-P into 3-keto-L-gulonate-6-P. Is essential for L-ascorbate utilization under anaerobic conditions K03476 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002187 280.0
MMD2_k127_2224924_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000001307 223.0
MMD2_k127_2224924_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000002878 153.0
MMD2_k127_2224924_4 - - - - 0.00000000002107 73.0
MMD2_k127_2224924_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0001367 48.0
MMD2_k127_2353116_0 Putative nucleotide-binding of sugar-metabolising enzyme K22129 - 2.7.1.219,2.7.1.220 0.000000000000000000000000000000000000000000000000000000000002731 219.0
MMD2_k127_2353116_1 MobA-like NTP transferase domain K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000001045 197.0
MMD2_k127_2353116_2 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000004003 145.0
MMD2_k127_2353116_3 - - - - 0.000000000002026 80.0
MMD2_k127_2359204_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 359.0
MMD2_k127_2359204_1 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 319.0
MMD2_k127_2359204_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001192 271.0
MMD2_k127_2359204_3 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000837 250.0
MMD2_k127_2359204_4 TOBE domain K02052 - - 0.0000000000000000000000000000000000000000000000000000000000000009118 228.0
MMD2_k127_2359204_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000002814 171.0
MMD2_k127_2359204_6 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000002788 143.0
MMD2_k127_2359204_7 Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000002624 96.0
MMD2_k127_2388887_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 2.424e-299 954.0
MMD2_k127_2388887_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.000000000000000000000000000000000000000000000000000000000000001165 232.0
MMD2_k127_2388887_2 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000001608 171.0
MMD2_k127_2388887_3 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000008561 83.0
MMD2_k127_2388887_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000002334 80.0
MMD2_k127_2388887_5 Sec61beta family - - - 0.0000004618 53.0
MMD2_k127_2388887_6 - - - - 0.0001586 53.0
MMD2_k127_248467_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004859 526.0
MMD2_k127_248467_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 376.0
MMD2_k127_248467_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001038 264.0
MMD2_k127_248467_3 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000001057 203.0
MMD2_k127_248467_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000005982 111.0
MMD2_k127_248467_5 Polysaccharide biosynthesis protein - - - 0.000000000000008155 87.0
MMD2_k127_248691_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 520.0
MMD2_k127_248691_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 374.0
MMD2_k127_248691_10 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000003614 77.0
MMD2_k127_248691_11 Transcriptional regulator K03718 - - 0.0000000000008347 74.0
MMD2_k127_248691_12 Threonyl and Alanyl tRNA synthetase second additional domain - - - 0.00000000005621 65.0
MMD2_k127_248691_13 Uncharacterised protein family (UPF0175) - - - 0.00004824 51.0
MMD2_k127_248691_14 nucleic acid-binding protein, contains PIN domain - - - 0.0001243 51.0
MMD2_k127_248691_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 311.0
MMD2_k127_248691_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 292.0
MMD2_k127_248691_4 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000002842 273.0
MMD2_k127_248691_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000961 233.0
MMD2_k127_248691_6 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000209 170.0
MMD2_k127_248691_7 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000003137 168.0
MMD2_k127_248691_8 Ser thr protein kinase K07176 - - 0.0000000000000000000000000000000000000000001607 168.0
MMD2_k127_248691_9 Belongs to the UPF0200 family - - - 0.00000000000000000000007556 102.0
MMD2_k127_2506068_0 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000002124 186.0
MMD2_k127_2506068_1 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000197 168.0
MMD2_k127_2506068_2 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000000000002926 151.0
MMD2_k127_2506068_3 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.0000000000000000000000000000003757 131.0
MMD2_k127_2506068_4 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000002798 131.0
MMD2_k127_2506068_5 MgtC family K07507 - - 0.000002578 49.0
MMD2_k127_2519960_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 479.0
MMD2_k127_2519960_1 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004528 447.0
MMD2_k127_2519960_10 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.0000007118 61.0
MMD2_k127_2519960_11 - - - - 0.00051 51.0
MMD2_k127_2519960_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 331.0
MMD2_k127_2519960_3 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004685 316.0
MMD2_k127_2519960_4 geranylgeranyl reductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005057 254.0
MMD2_k127_2519960_5 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000004726 192.0
MMD2_k127_2519960_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000002298 186.0
MMD2_k127_2519960_7 - - - - 0.0000000000000000000000008817 109.0
MMD2_k127_2519960_8 - - - - 0.00000000000000000000004626 106.0
MMD2_k127_2519960_9 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.000000000000000000006835 94.0
MMD2_k127_2532362_0 Belongs to the aldehyde dehydrogenase family K00128,K00130,K00135,K00138,K00146 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.39,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 524.0
MMD2_k127_2532362_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000003912 122.0
MMD2_k127_2532362_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000408 43.0
MMD2_k127_2551912_0 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000000000000000000000000003267 233.0
MMD2_k127_2551912_1 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000004606 188.0
MMD2_k127_2551912_2 Response regulator receiver K02483,K07658,K07668 - - 0.000000000000000000000000000000002146 132.0
MMD2_k127_2551912_3 Rieske-like [2Fe-2S] domain - - - 0.000000000000000000000000000000739 126.0
MMD2_k127_2551912_4 Glutaredoxin - - - 0.0000000000000000000000000006725 114.0
MMD2_k127_2551912_5 PFAM Rieske 2Fe-2S domain K05710 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000002513 116.0
MMD2_k127_2551912_6 Universal stress protein - - - 0.00000000000000000001228 99.0
MMD2_k127_2582538_0 Aminotransferase K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 432.0
MMD2_k127_2582538_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 349.0
MMD2_k127_2582538_2 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000008754 195.0
MMD2_k127_2582538_3 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000001536 171.0
MMD2_k127_2582538_4 PFAM Molybdopterin guanine dinucleotide synthesis protein B K06947 - - 0.000000000000000000002743 101.0
MMD2_k127_2582538_5 COG3209 Rhs family protein - - - 0.000009198 58.0
MMD2_k127_2610444_0 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001117 237.0
MMD2_k127_2610444_1 PFAM PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000004206 190.0
MMD2_k127_2610444_2 Belongs to the peptidase S16 family K06870 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000003117 131.0
MMD2_k127_2610444_3 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.000000000000000000001962 103.0
MMD2_k127_2610444_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00003995 50.0
MMD2_k127_2652259_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 9.462e-283 886.0
MMD2_k127_2652259_1 Domain of unknown function (DUF1610) K07580 - - 0.0000000000000004873 79.0
MMD2_k127_2652259_2 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000001793 67.0
MMD2_k127_2652259_3 - - - - 0.00000001716 58.0
MMD2_k127_2652259_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.00001083 51.0
MMD2_k127_2726869_0 DNA polymerase K02319 - 2.7.7.7 1.138e-248 794.0
MMD2_k127_2726869_1 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000000000000176 241.0
MMD2_k127_2726869_2 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000004899 198.0
MMD2_k127_2726869_3 TIGRFAM F420-dependent oxidoreductase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000005591 189.0
MMD2_k127_2726869_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000002531 196.0
MMD2_k127_2726869_5 Proton-conducting membrane transporter K05565,K12137 - - 0.000000000000000000000000000000000000000000000009732 190.0
MMD2_k127_2726869_6 4Fe-4S dicluster domain K00124 - - 0.00000000000000000000000000000000000000001669 158.0
MMD2_k127_274300_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 3.368e-195 625.0
MMD2_k127_274300_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 352.0
MMD2_k127_274300_10 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.000000000000001616 78.0
MMD2_k127_274300_11 SMART Nucleotide binding protein, PINc K07158 - - 0.000000294 55.0
MMD2_k127_274300_12 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000006891 57.0
MMD2_k127_274300_2 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000001556 218.0
MMD2_k127_274300_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000002176 168.0
MMD2_k127_274300_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000917 164.0
MMD2_k127_274300_5 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000002988 115.0
MMD2_k127_274300_6 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000001206 111.0
MMD2_k127_274300_7 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000001616 89.0
MMD2_k127_274300_8 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000006742 84.0
MMD2_k127_274300_9 Belongs to the UPF0218 family K09735 - - 0.0000000000000001519 88.0
MMD2_k127_2749600_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 1.232e-270 850.0
MMD2_k127_2749600_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 420.0
MMD2_k127_2749600_2 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000452 228.0
MMD2_k127_2749600_3 Diphthamide synthase K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000883 205.0
MMD2_k127_2749600_4 - - - - 0.0000000000006031 71.0
MMD2_k127_2749600_5 Cytochrome c - - - 0.0000006437 54.0
MMD2_k127_2749600_6 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.000002198 52.0
MMD2_k127_2749600_7 Phage integrase family - - - 0.0006341 44.0
MMD2_k127_2754352_0 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 576.0
MMD2_k127_2754352_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000003191 250.0
MMD2_k127_2754352_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000000000004702 106.0
MMD2_k127_2754352_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000256 74.0
MMD2_k127_2754352_4 - - - - 0.0000000000005299 80.0
MMD2_k127_2754352_5 4Fe-4S ferredoxin iron-sulfur binding - - - 0.00001261 49.0
MMD2_k127_2842894_0 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000002382 246.0
MMD2_k127_2842894_1 Binds the lower part of the 30S subunit head K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002712 213.0
MMD2_k127_2842894_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001024 200.0
MMD2_k127_2842894_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.0000000000000000000000000000000000000000000000000006909 186.0
MMD2_k127_2842894_4 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000001312 129.0
MMD2_k127_2842894_5 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000008498 99.0
MMD2_k127_2842894_6 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000000000000000418 90.0
MMD2_k127_2842894_7 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000001565 72.0
MMD2_k127_2842894_8 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000009229 64.0
MMD2_k127_2903085_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.065e-286 906.0
MMD2_k127_2903085_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 462.0
MMD2_k127_2903085_10 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.000000343 53.0
MMD2_k127_2903085_2 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 434.0
MMD2_k127_2903085_3 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001785 234.0
MMD2_k127_2903085_4 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0043774,GO:0044424,GO:0044464 6.3.4.23 0.000000000000000000000000000000000000000000000000005746 184.0
MMD2_k127_2903085_5 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000007789 153.0
MMD2_k127_2903085_6 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.0000000000000000000000000008598 120.0
MMD2_k127_2903085_7 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000004408 87.0
MMD2_k127_2903085_8 CAAX protease self-immunity - - - 0.00000000263 68.0
MMD2_k127_2903085_9 metal-sulfur cluster biosynthetic enzyme K02612,K04488 - - 0.00000007254 60.0
MMD2_k127_2927478_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 2.376e-238 750.0
MMD2_k127_2927478_1 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.000000000000000000008631 93.0
MMD2_k127_2927478_2 VIT family - - - 0.0000000000001278 78.0
MMD2_k127_2927478_3 protein conserved in archaea K09732 - - 0.0000000000737 66.0
MMD2_k127_2927478_4 Glycosyltransferase Family 4 K21369 - 2.4.1.270 0.0000001027 58.0
MMD2_k127_3042374_0 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 413.0
MMD2_k127_3042374_1 PFAM Beta propeller domain K14475 - - 0.0000000000001896 78.0
MMD2_k127_3042374_2 SPFH domain-Band 7 family - - - 0.00001082 53.0
MMD2_k127_3042374_3 - - - - 0.00007133 55.0
MMD2_k127_3075917_0 glycosyl transferase family 2 K00786 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003832 262.0
MMD2_k127_3075917_1 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000001869 234.0
MMD2_k127_3075917_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000004271 232.0
MMD2_k127_3075917_3 Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000004905 188.0
MMD2_k127_3075917_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000001468 151.0
MMD2_k127_3076301_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 363.0
MMD2_k127_3076301_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007775 295.0
MMD2_k127_3076301_2 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003157 263.0
MMD2_k127_3076301_3 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000003103 119.0
MMD2_k127_3076301_4 Psort location CytoplasmicMembrane, score 10.00 K08978 - - 0.00005434 54.0
MMD2_k127_3109655_0 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000008788 224.0
MMD2_k127_3109655_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000002588 175.0
MMD2_k127_3109655_2 Uncharacterized conserved protein (DUF2304) K09153 - - 0.00000000835 61.0
MMD2_k127_3146709_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000047 342.0
MMD2_k127_3146709_1 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000001318 235.0
MMD2_k127_3146709_2 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.000000000000000000000000000000000139 141.0
MMD2_k127_3146709_3 protein secretion by the type IV secretion system - - - 0.000000000000000000000000001174 129.0
MMD2_k127_3146709_4 - - - - 0.0000003863 57.0
MMD2_k127_3181267_0 COG0433 Predicted ATPase K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 371.0
MMD2_k127_3181267_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000008828 250.0
MMD2_k127_3181267_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000005408 244.0
MMD2_k127_3181267_3 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000003818 186.0
MMD2_k127_3181267_4 PFAM NurA domain - - - 0.0000000000000000001747 101.0
MMD2_k127_3181267_5 Ribosomal protein S30 K02983 - - 0.0000000006137 61.0
MMD2_k127_3207206_0 XanTHIne and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000002 210.0
MMD2_k127_3207206_1 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000015 204.0
MMD2_k127_3207206_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000008027 114.0
MMD2_k127_3207206_3 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000001184 112.0
MMD2_k127_3207206_4 - - - - 0.000000000000808 74.0
MMD2_k127_3221595_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 532.0
MMD2_k127_3221595_1 V-type ATPase 116kDa subunit family K02123 - - 0.0000000000000000000000000000000000000000000000000000006506 216.0
MMD2_k127_3221595_2 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000006359 76.0
MMD2_k127_3221595_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000005231 77.0
MMD2_k127_3221595_4 ATPase subunit C K02119 - - 0.0000002904 60.0
MMD2_k127_3221595_5 ACT domain - - - 0.0006429 45.0
MMD2_k127_3241003_0 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 5.329e-219 704.0
MMD2_k127_3241003_1 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 2.112e-199 634.0
MMD2_k127_3241003_10 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000003713 93.0
MMD2_k127_3241003_11 PFAM Peptidase S53, propeptide - - - 0.00000000000000007846 92.0
MMD2_k127_3241003_12 TOPRIM - - - 0.00000000000004866 77.0
MMD2_k127_3241003_13 Belongs to the ubiquitin-conjugating enzyme family K10579 - - 0.0000000000002179 78.0
MMD2_k127_3241003_14 nucleic acid binding protein containing the AN1-type Zn-finger K07059 - - 0.00000008053 63.0
MMD2_k127_3241003_15 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000307 55.0
MMD2_k127_3241003_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 377.0
MMD2_k127_3241003_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 349.0
MMD2_k127_3241003_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000307 226.0
MMD2_k127_3241003_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000002796 183.0
MMD2_k127_3241003_6 PFAM Peptidase - - - 0.000000000000000000000000000000003271 138.0
MMD2_k127_3241003_7 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000005455 137.0
MMD2_k127_3241003_8 protein secretion by the type IV secretion system - - - 0.0000000000000000000000000002667 134.0
MMD2_k127_3241003_9 transcriptional regulatory protein K09714 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000001107 95.0
MMD2_k127_3318200_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 441.0
MMD2_k127_3318200_1 Subunit A of antiporter complex involved in resistance to high concentrations of Na , K , Li and or alkali K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000094 418.0
MMD2_k127_3318200_10 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000001058 56.0
MMD2_k127_3318200_12 Hydrogenase maturation protease K08315 - 3.4.23.51 0.00001207 49.0
MMD2_k127_3318200_2 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 331.0
MMD2_k127_3318200_3 NADH dehydrogenase I, subunit N related protein K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 325.0
MMD2_k127_3318200_4 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005875 254.0
MMD2_k127_3318200_5 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000144 205.0
MMD2_k127_3318200_6 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000004607 123.0
MMD2_k127_3318200_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14091 - - 0.000000000000000000004982 96.0
MMD2_k127_3318200_8 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.00000000000000000001532 98.0
MMD2_k127_3318200_9 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05567 - - 0.00000000000004039 76.0
MMD2_k127_3349364_0 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000009581 250.0
MMD2_k127_3349364_1 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000000000000000000000000000000000000007832 194.0
MMD2_k127_3349364_2 ECF-type riboflavin transporter, S component - - - 0.00000000000000000007853 93.0
MMD2_k127_3349364_3 snRNP Sm proteins K04796 - - 0.0000000000000347 75.0
MMD2_k127_3349364_4 PFAM ParB domain protein nuclease - - - 0.000000000006684 73.0
MMD2_k127_3362335_0 GTPase of unknown function C-terminal K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 371.0
MMD2_k127_3362335_1 Protein of unknown function (DUF1512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 312.0
MMD2_k127_3362335_2 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000003384 268.0
MMD2_k127_3362335_3 metalloendopeptidase activity - - - 0.0000001451 58.0
MMD2_k127_3381848_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 321.0
MMD2_k127_3381848_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005873 292.0
MMD2_k127_3381848_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000003584 145.0
MMD2_k127_3381848_3 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000001697 131.0
MMD2_k127_3427761_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 394.0
MMD2_k127_3427761_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 308.0
MMD2_k127_3427761_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 301.0
MMD2_k127_3427761_3 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000004875 259.0
MMD2_k127_3429547_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000001485 189.0
MMD2_k127_3429547_1 type II secretion system protein K07333 - - 0.00000001132 58.0
MMD2_k127_3456062_0 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 413.0
MMD2_k127_3456062_1 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 360.0
MMD2_k127_3456062_2 Belongs to the FPP GGPP synthase family K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000004606 111.0
MMD2_k127_3460673_0 succinate dehydrogenase or fumarate reductase, flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 572.0
MMD2_k127_3460673_1 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 340.0
MMD2_k127_3460673_2 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000149 238.0
MMD2_k127_3568447_0 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 554.0
MMD2_k127_3568447_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005688 280.0
MMD2_k127_3568447_2 AAA-like domain - - - 0.000000000000000000000000000000000000000007346 165.0
MMD2_k127_3568447_3 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.0000000000000000000001744 99.0
MMD2_k127_3585526_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.995e-215 680.0
MMD2_k127_3585526_1 Response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000007082 126.0
MMD2_k127_3662959_0 DnaB-like helicase C terminal domain K08482 - - 0.00000000000000000000000000000000000023 150.0
MMD2_k127_3662959_1 phosphatidylinositol metabolic process - - - 0.000000000000000000000000003188 125.0
MMD2_k127_3662959_2 regulation of circadian rhythm K08282 - 2.7.11.1 0.0000000001519 74.0
MMD2_k127_3662959_3 - - - - 0.0001583 55.0
MMD2_k127_3681234_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1076.0
MMD2_k127_3681234_1 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005748 387.0
MMD2_k127_3681234_2 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 347.0
MMD2_k127_3732370_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 1.839e-205 656.0
MMD2_k127_3732370_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000004317 212.0
MMD2_k127_3732370_3 Universal stress protein K06149 - - 0.000000001237 66.0
MMD2_k127_374911_0 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 330.0
MMD2_k127_374911_1 bacteriocin export ABC transporter, lactococcin 972 group K02003 - - 0.0000000000000000000000000000001459 125.0
MMD2_k127_374911_2 membrane - - - 0.000000000000000000000000000002018 127.0
MMD2_k127_374911_3 von Willebrand factor type A domain K07114 - - 0.00000004729 66.0
MMD2_k127_374911_4 PFAM protein phosphatase 2C K01090 - 3.1.3.16 0.000003721 52.0
MMD2_k127_3759205_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000005194 224.0
MMD2_k127_3759205_1 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.0000000000000000000000000000000000000000000000000000007915 198.0
MMD2_k127_3759205_2 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000001375 108.0
MMD2_k127_3759205_3 PFAM Putitive phosphate transport regulator K07220 - - 0.0000006639 59.0
MMD2_k127_3872432_0 NAD-dependent epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 362.0
MMD2_k127_3872432_1 Rhamnan synthesis protein F - - - 0.00000000000000000000000000000000000000000000003351 184.0
MMD2_k127_3930968_0 AIR synthase related protein, C-terminal domain K01952 - 6.3.5.3 7.655e-212 680.0
MMD2_k127_3930968_1 FAD-dependent K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 569.0
MMD2_k127_3930968_2 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 430.0
MMD2_k127_3930968_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 301.0
MMD2_k127_3930968_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001681 274.0
MMD2_k127_3930968_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000005364 167.0
MMD2_k127_3930968_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000007262 85.0
MMD2_k127_3930968_7 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000001511 83.0
MMD2_k127_3930968_8 PFAM metallophosphoesterase K06953 - - 0.0000001318 55.0
MMD2_k127_3966472_0 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 5.872e-209 668.0
MMD2_k127_3966472_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 492.0
MMD2_k127_3966472_10 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000003812 51.0
MMD2_k127_3966472_2 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 377.0
MMD2_k127_3966472_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 339.0
MMD2_k127_3966472_4 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.00000000000000000000000000000000000000000000000000000000000000000000000000007023 272.0
MMD2_k127_3966472_5 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000009437 216.0
MMD2_k127_3966472_6 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000007459 183.0
MMD2_k127_3966472_7 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000001648 128.0
MMD2_k127_3966472_8 COG1522 Transcriptional regulators - - - 0.000000000000000001115 91.0
MMD2_k127_3966472_9 H ACA RNA-protein complex K07569 - - 0.0000000000004649 74.0
MMD2_k127_3970857_0 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006285 519.0
MMD2_k127_3970857_1 PFAM Iron-containing alcohol dehydrogenase K13954,K19954 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 293.0
MMD2_k127_3990015_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 499.0
MMD2_k127_3990015_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.0000000000000000000000000000000000000000000000001276 186.0
MMD2_k127_3990015_2 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000001436 177.0
MMD2_k127_3990015_3 O-methyltransferase activity K00545 - 2.1.1.6 0.000000000000000000000000006107 117.0
MMD2_k127_3990555_0 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001202 280.0
MMD2_k127_3990555_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000002613 181.0
MMD2_k127_3990555_2 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.000000000000000000000000000000000000000000000004866 182.0
MMD2_k127_3990555_3 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.0000000000000000000000000000000000000000000005896 170.0
MMD2_k127_3990555_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.00000000000000000000000000000000843 134.0
MMD2_k127_3990555_5 protein conserved in archaea (DUF2095) - - - 0.0000000000000000006181 90.0
MMD2_k127_3990555_6 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.00000000009927 67.0
MMD2_k127_4008225_0 TIGRFAM 2-methylcitrate synthase citrate synthase II K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 402.0
MMD2_k127_4008225_1 Cytochrome b - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 342.0
MMD2_k127_4008225_2 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases K00467 - 1.13.12.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 315.0
MMD2_k127_4008225_3 PFAM Rieske 2Fe-2S domain - - - 0.000000000000000000000000000000000000000000003863 171.0
MMD2_k127_4017981_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 576.0
MMD2_k127_4017981_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005067 387.0
MMD2_k127_4017981_2 GMP synthase, glutamine-hydrolyzing K01951 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 311.0
MMD2_k127_4039787_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 6.044e-212 674.0
MMD2_k127_4039787_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006761 362.0
MMD2_k127_4039787_2 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007932 258.0
MMD2_k127_4039787_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000026 198.0
MMD2_k127_4039787_4 TIGRFAM archaeoflavoprotein AfpA - - - 0.000000000000000000000000000000000000000141 156.0
MMD2_k127_4053215_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 467.0
MMD2_k127_4053215_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 451.0
MMD2_k127_4053215_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 403.0
MMD2_k127_4053215_3 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001002 292.0
MMD2_k127_4053215_4 nucleotide-excision repair K03701 - - 0.000000000000000000000000000000000000006185 147.0
MMD2_k127_4053215_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000001068 65.0
MMD2_k127_4053215_6 Glycogen debranching enzyme - - - 0.000005983 58.0
MMD2_k127_4062218_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 7.55e-215 684.0
MMD2_k127_4062218_1 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 470.0
MMD2_k127_4062218_2 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000001649 209.0
MMD2_k127_4062218_3 membrane-associated Zn-dependent proteases 1 - - - 0.0000000000000000000000000000000000000000000000000104 194.0
MMD2_k127_4062218_4 nitroreductase K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000009304 177.0
MMD2_k127_4062218_5 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.0000000000000000000000000000000000000000002788 164.0
MMD2_k127_4062218_6 alpha/beta hydrolase fold - - - 0.000000000000000009307 87.0
MMD2_k127_4062218_7 - - - - 0.000000000000002618 85.0
MMD2_k127_4062660_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.74e-246 780.0
MMD2_k127_4062660_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 593.0
MMD2_k127_4062660_10 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000007974 129.0
MMD2_k127_4062660_11 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000001558 121.0
MMD2_k127_4062660_12 Cytidylyltransferase K19712 - 2.7.7.62 0.000000000000000000000000006303 120.0
MMD2_k127_4062660_13 Transporter, major facilitator family protein K08369 - - 0.0000000000000000000000000065 114.0
MMD2_k127_4062660_14 Domain of unknown function (DUF4443) - - - 0.000000000000000000000002347 111.0
MMD2_k127_4062660_15 Adenosylcobinamide amidohydrolase - - - 0.00000000003271 75.0
MMD2_k127_4062660_16 CAAX protease self-immunity K07052 - - 0.0000000003521 70.0
MMD2_k127_4062660_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000004379 64.0
MMD2_k127_4062660_18 ThiS family K03636 - - 0.000000005892 62.0
MMD2_k127_4062660_2 PFAM ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 367.0
MMD2_k127_4062660_3 Belongs to the UPF0284 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 315.0
MMD2_k127_4062660_4 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 311.0
MMD2_k127_4062660_5 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 296.0
MMD2_k127_4062660_6 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000001686 256.0
MMD2_k127_4062660_7 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000648 240.0
MMD2_k127_4062660_8 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000001153 170.0
MMD2_k127_4062660_9 PFAM Phosphatidylglycerophosphatase A - - - 0.0000000000000000000000000000000007309 144.0
MMD2_k127_4075698_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1442.0
MMD2_k127_4075698_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1290.0
MMD2_k127_4075698_10 metallopeptidase activity K03030 GO:0000266,GO:0000502,GO:0000724,GO:0000725,GO:0000726,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004175,GO:0004843,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006310,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006950,GO:0006955,GO:0006970,GO:0006974,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008047,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009628,GO:0009651,GO:0009893,GO:0009894,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010604,GO:0010638,GO:0010950,GO:0010952,GO:0010965,GO:0012505,GO:0016043,GO:0016192,GO:0016504,GO:0016559,GO:0016579,GO:0016787,GO:0019222,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030141,GO:0030162,GO:0030163,GO:0030234,GO:0031323,GO:0031325,GO:0031329,GO:0031331,GO:0031410,GO:0031597,GO:0031974,GO:0031981,GO:0031982,GO:0031983,GO:0032268,GO:0032270,GO:0032436,GO:0032940,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0033554,GO:0034399,GO:0034515,GO:0034622,GO:0034641,GO:0034774,GO:0036211,GO:0036230,GO:0036459,GO:0042119,GO:0042176,GO:0043085,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043299,GO:0043312,GO:0043412,GO:0043632,GO:0043687,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044433,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045055,GO:0045321,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0046483,GO:0046903,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051336,GO:0051345,GO:0051603,GO:0051716,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061133,GO:0061134,GO:0061135,GO:0061136,GO:0061578,GO:0062033,GO:0065003,GO:0065007,GO:0065009,GO:0070011,GO:0070013,GO:0070536,GO:0070628,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0080090,GO:0090068,GO:0090304,GO:0097708,GO:0098772,GO:0099503,GO:0101002,GO:0101005,GO:0140096,GO:1901360,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1904813,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000000003661 77.0
MMD2_k127_4075698_11 COG3209 Rhs family protein - - - 0.00000000003191 75.0
MMD2_k127_4075698_12 QueT transporter - - - 0.000000002233 64.0
MMD2_k127_4075698_2 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0 1071.0
MMD2_k127_4075698_3 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000231 277.0
MMD2_k127_4075698_4 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.0000000000000000000000000000000000000000000000000005356 189.0
MMD2_k127_4075698_5 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.000000000000000000000000000000000000000568 150.0
MMD2_k127_4075698_6 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000001524 152.0
MMD2_k127_4075698_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000001119 97.0
MMD2_k127_4075698_8 Belongs to the eukaryotic ribosomal protein eL30 family K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000133 100.0
MMD2_k127_4075698_9 GDP-mannose mannosyl hydrolase activity - - - 0.00000000000000000001256 96.0
MMD2_k127_4080167_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 582.0
MMD2_k127_4080167_1 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004113 245.0
MMD2_k127_4080167_2 Phosphate transporter family K03306 - - 0.00000000000000009124 82.0
MMD2_k127_4080167_3 Protein of unknown function (DUF541) K09807 - - 0.00000000000003556 78.0
MMD2_k127_4080167_4 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000003356 53.0
MMD2_k127_4146351_0 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002715 281.0
MMD2_k127_4146351_1 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003424 266.0
MMD2_k127_4146351_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002254 273.0
MMD2_k127_4146351_3 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000006826 201.0
MMD2_k127_4146351_4 Bacterial lipoate protein ligase C-terminus K03800 - 6.3.1.20 0.00000000003788 67.0
MMD2_k127_4183860_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 473.0
MMD2_k127_4183860_1 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 436.0
MMD2_k127_4183860_10 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.00000000000000000000000000000000000003867 151.0
MMD2_k127_4183860_11 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001814 108.0
MMD2_k127_4183860_12 SMART Nucleotide binding protein, PINc K07060 - - 0.00000000000000000002306 98.0
MMD2_k127_4183860_13 PFAM SNARE associated Golgi protein - - - 0.0000000000000009171 85.0
MMD2_k127_4183860_14 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000002519 65.0
MMD2_k127_4183860_15 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.0000001252 58.0
MMD2_k127_4183860_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 270.0
MMD2_k127_4183860_3 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000001039 245.0
MMD2_k127_4183860_4 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000000000004449 205.0
MMD2_k127_4183860_5 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000001066 188.0
MMD2_k127_4183860_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000001263 176.0
MMD2_k127_4183860_7 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001229 165.0
MMD2_k127_4183860_8 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000007715 160.0
MMD2_k127_4183860_9 Methyltransferase small domain K07579 - - 0.000000000000000000000000000000000000001453 156.0
MMD2_k127_4190452_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 346.0
MMD2_k127_4190452_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000000000000000000000000000000000000000000000000000000000000000000000001625 251.0
MMD2_k127_4190452_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000002475 95.0
MMD2_k127_4190452_3 Belongs to the UPF0216 family K09737 - - 0.0000000001879 67.0
MMD2_k127_4220137_0 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000001609 233.0
MMD2_k127_4220137_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000008637 82.0
MMD2_k127_4220137_2 PFAM CBS domain containing protein - - - 0.000009917 57.0
MMD2_k127_4228591_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003994 399.0
MMD2_k127_4228591_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000004317 237.0
MMD2_k127_4228591_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001871 210.0
MMD2_k127_4228591_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000002732 184.0
MMD2_k127_4228591_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000009612 170.0
MMD2_k127_4228591_5 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000003538 121.0
MMD2_k127_4228591_6 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000004387 114.0
MMD2_k127_4228591_7 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000115 112.0
MMD2_k127_4228591_8 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000008093 104.0
MMD2_k127_4228591_9 Binds to the 23S rRNA K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000009598 102.0
MMD2_k127_4363268_0 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000004939 258.0
MMD2_k127_4363268_2 Lamin Tail Domain - - - 0.000000000001269 78.0
MMD2_k127_4396092_0 Phosphomethylpyrimidine kinase K00941,K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 482.0
MMD2_k127_4396092_1 Radical SAM K11781 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 459.0
MMD2_k127_4396092_10 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.0000000000000000000005846 100.0
MMD2_k127_4396092_11 protein transport - - - 0.000000000000000003362 89.0
MMD2_k127_4396092_12 Cytochrome c K01179,K03646,K03832 - 3.2.1.4 0.0000001618 57.0
MMD2_k127_4396092_13 - - - - 0.0001184 53.0
MMD2_k127_4396092_2 Permease for cytosine/purines, uracil, thiamine, allantoin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 427.0
MMD2_k127_4396092_3 Elongator protein 3, MiaB family, Radical SAM K11779 - 2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 392.0
MMD2_k127_4396092_4 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002518 288.0
MMD2_k127_4396092_5 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004517 273.0
MMD2_k127_4396092_6 Catalyzes the formation of 2-amino-5-formylamino-6- ribofuranosylamino-4(3H)-pyrimidinone ribonucleotide monophosphate and inorganic phosphate from GTP. Also has an independent pyrophosphate phosphohydrolase activity K08096 - 3.5.4.29 0.0000000000000000000000000000000000000000000000000000000000000159 224.0
MMD2_k127_4396092_7 PFAM bifunctional deaminase-reductase domain protein K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000001293 211.0
MMD2_k127_4396092_8 TIGRFAM thiW protein - - - 0.000000000000000000000000000000000001177 144.0
MMD2_k127_4396092_9 - - - - 0.0000000000000000000002903 104.0
MMD2_k127_442037_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 499.0
MMD2_k127_442037_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000003865 179.0
MMD2_k127_442037_2 4Fe-4S binding domain - - - 0.000000000000000000000009362 112.0
MMD2_k127_442037_3 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000008099 109.0
MMD2_k127_442335_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 1.796e-216 686.0
MMD2_k127_442335_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000001234 195.0
MMD2_k127_442335_2 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000000000000007007 193.0
MMD2_k127_442335_3 mandelate racemase muconate lactonizing K20023 - 4.2.1.156,4.2.1.42 0.000000000000000000000000000000000000000001908 163.0
MMD2_k127_442335_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000005546 159.0
MMD2_k127_442335_5 NIPSNAP - - - 0.00000000000000000000000000000003221 128.0
MMD2_k127_4445215_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 320.0
MMD2_k127_4445215_1 transferase activity, transferring glycosyl groups K06984 - 2.4.2.54 0.00000000000000000000001087 105.0
MMD2_k127_4445215_2 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.0000000000000001183 86.0
MMD2_k127_4445215_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000007903 74.0
MMD2_k127_4445215_4 Protein of unknown function (DUF447) K09154 - - 0.0000000007401 68.0
MMD2_k127_446362_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008653 488.0
MMD2_k127_446362_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000286 130.0
MMD2_k127_446362_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000003093 122.0
MMD2_k127_4467358_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 395.0
MMD2_k127_4467358_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 351.0
MMD2_k127_4467358_2 4Fe-4S binding domain - - - 0.0001222 46.0
MMD2_k127_4561842_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.000000000000000000000000000000000000000000000005306 184.0
MMD2_k127_4561842_1 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000006471 169.0
MMD2_k127_457587_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 544.0
MMD2_k127_457587_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000305 282.0
MMD2_k127_457587_2 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000108 278.0
MMD2_k127_457587_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000001054 163.0
MMD2_k127_457587_4 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000001498 153.0
MMD2_k127_457587_5 regulatory protein, arsR - - - 0.000000000002391 71.0
MMD2_k127_4591028_0 serine acetyltransferase K00640 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016053,GO:0016054,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000008023 255.0
MMD2_k127_4591028_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000002523 222.0
MMD2_k127_4591028_2 dehydrogenases and related proteins - - - 0.000000000000000000000000000001645 132.0
MMD2_k127_4660353_0 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000001199 199.0
MMD2_k127_4660353_1 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000000000000000000000000006364 170.0
MMD2_k127_4660353_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000009808 150.0
MMD2_k127_4660353_3 FemAB family - - - 0.000000002271 69.0
MMD2_k127_4753921_0 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000005303 134.0
MMD2_k127_4753921_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000004936 124.0
MMD2_k127_4753921_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000002621 105.0
MMD2_k127_4787581_0 FAD linked oxidases, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 394.0
MMD2_k127_4787581_1 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000005922 231.0
MMD2_k127_4787581_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.0000000000000000000000000000000000000000000009996 171.0
MMD2_k127_4787581_3 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K00123,K00390,K00441,K03388,K14121,K22174 - 1.1.98.4,1.12.98.1,1.17.1.9,1.8.4.10,1.8.4.8,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000001236 123.0
MMD2_k127_4787581_4 glycine decarboxylation via glycine cleavage system K02437 - - 0.00000000000000000000000001102 119.0
MMD2_k127_4787581_5 4Fe-4S dicluster domain - - - 0.00000000000000000000001795 108.0
MMD2_k127_479501_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004758 314.0
MMD2_k127_479501_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000006038 238.0
MMD2_k127_479501_2 Oxidoreductase, short chain dehydrogenase reductase family protein K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000243 166.0
MMD2_k127_479501_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000003863 143.0
MMD2_k127_4798650_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002064 261.0
MMD2_k127_4798650_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000004712 193.0
MMD2_k127_4798650_2 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000000000000000000000000000000005592 177.0
MMD2_k127_4798650_3 ABC-type transport system involved in cytochrome c biogenesis, permease component K02195 - - 0.0000000000000000000000000000000000000000000006867 174.0
MMD2_k127_4798650_4 Cytochrome c3 - - - 0.000000000000000000000000000000009942 136.0
MMD2_k127_4798650_5 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.000000000000000000000003519 111.0
MMD2_k127_4798650_6 Hydrogenase expression formation protein K03605 - - 0.00000000000004825 76.0
MMD2_k127_4798650_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000001275 66.0
MMD2_k127_4798650_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000003742 61.0
MMD2_k127_4830845_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.748e-237 763.0
MMD2_k127_4830845_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 524.0
MMD2_k127_4830845_2 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 480.0
MMD2_k127_4830845_3 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000001018 130.0
MMD2_k127_4836894_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 458.0
MMD2_k127_4836894_1 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006638 299.0
MMD2_k127_4836894_2 conserved protein, contains double-stranded beta-helix domain - - - 0.00000000002621 68.0
MMD2_k127_4842786_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002677 271.0
MMD2_k127_4842786_1 PFAM ribosomal protein S8E K02995 - - 0.00000000000000000000000000005574 121.0
MMD2_k127_4842786_2 Segregation and condensation complex subunit ScpB K06024 - - 0.0000000000000000000000000007599 121.0
MMD2_k127_4842786_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006605,GO:0006612,GO:0006613,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008312,GO:0015031,GO:0015833,GO:0033036,GO:0034613,GO:0042886,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0072657,GO:0090150,GO:0097159,GO:1901363 - 0.000000000000001939 79.0
MMD2_k127_4842786_4 chromosome segregation and condensation protein ScpA K05896 - - 0.000002143 58.0
MMD2_k127_4843589_0 heavy metal-(Cd Co Hg Pb Zn)-translocating K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 459.0
MMD2_k127_4843589_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 431.0
MMD2_k127_4843589_2 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001303 256.0
MMD2_k127_4862_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 - 1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 483.0
MMD2_k127_4862_1 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 356.0
MMD2_k127_4862_2 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 349.0
MMD2_k127_4862_3 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003874 319.0
MMD2_k127_4862_4 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000002577 217.0
MMD2_k127_4862_5 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.00000000000000000000000000000000000000000000008679 181.0
MMD2_k127_4862_6 Trm112p-like protein - - - 0.0000000000000000000000000002912 115.0
MMD2_k127_4905433_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 476.0
MMD2_k127_4905433_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 362.0
MMD2_k127_4905433_2 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.00000000000000000000000000000000000000000000000000007812 193.0
MMD2_k127_4905433_3 proteins of PilT N-term. Vapc superfamily K07158 - - 0.00000001038 62.0
MMD2_k127_4907552_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 8.404e-234 742.0
MMD2_k127_4907552_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 353.0
MMD2_k127_4907552_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 297.0
MMD2_k127_4907552_3 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000003505 70.0
MMD2_k127_4967450_0 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006412 293.0
MMD2_k127_4967450_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000001166 237.0
MMD2_k127_4967450_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000001043 175.0
MMD2_k127_4967450_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.0000000000000000000000000000000000001262 147.0
MMD2_k127_4967450_4 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000147 98.0
MMD2_k127_4967450_5 Belongs to the ribosomal protein L31e family K02910 - - 0.0000000000000003361 83.0
MMD2_k127_4967450_6 Structural constituent of ribosome. It is involved in the biological process described with K02924 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000004204 52.0
MMD2_k127_5005896_0 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.901e-195 624.0
MMD2_k127_5005896_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 426.0
MMD2_k127_5005896_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 333.0
MMD2_k127_5005896_3 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.0000000000000000000000000000000000000007792 149.0
MMD2_k127_5005896_4 CBS domain - - - 0.0000000000000000000000000000000005298 141.0
MMD2_k127_5005896_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014 - - 0.000000000000000003133 88.0
MMD2_k127_5005896_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000171 82.0
MMD2_k127_5005896_7 - K09143 - - 0.0000000002642 66.0
MMD2_k127_5005896_8 S25 ribosomal protein K02975 - - 0.0001452 49.0
MMD2_k127_5060370_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 260.0
MMD2_k127_5060370_1 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000003109 170.0
MMD2_k127_5060370_2 Cupin domain protein - - - 0.0000000000000000000000000000000000001099 145.0
MMD2_k127_5060370_3 PFAM Cobalt transport protein K02008 - - 0.000000000000000000000000007462 121.0
MMD2_k127_5060370_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K14091 - - 0.0000000000000000000004685 99.0
MMD2_k127_5060370_5 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.0008146 43.0
MMD2_k127_5070303_0 COG1199 Rad3-related DNA helicases - - - 0.0000000000000000000000000000000000000000000000000000000000001275 234.0
MMD2_k127_5070303_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002297 71.0
MMD2_k127_5075132_0 DEAD DEAH box helicase domain protein K03724 - - 7.986e-207 676.0
MMD2_k127_5075132_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 544.0
MMD2_k127_5075132_10 molybdopterin-guanine dinucleotide biosynthesis protein K03635,K03753 - 2.8.1.12 0.0001621 46.0
MMD2_k127_5075132_2 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 391.0
MMD2_k127_5075132_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 299.0
MMD2_k127_5075132_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000004371 226.0
MMD2_k127_5075132_5 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.0000000000000000000000000000000000000000000415 184.0
MMD2_k127_5075132_6 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000921 172.0
MMD2_k127_5075132_7 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.0000000000000000000000000000000009795 136.0
MMD2_k127_5075132_8 PPIC-type PPIASE domain K07533 - 5.2.1.8 0.00000000000000000000000001705 110.0
MMD2_k127_5075132_9 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.000000000000000004814 85.0
MMD2_k127_5078854_0 Domain of unknown function (DUF4445) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 524.0
MMD2_k127_5078854_1 synthase K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 300.0
MMD2_k127_5078854_2 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.000000000000000009085 84.0
MMD2_k127_5078854_3 - - - - 0.000000001013 68.0
MMD2_k127_5125626_0 peptide catabolic process K13722 - - 3e-233 745.0
MMD2_k127_5125626_1 PFAM Aminotransferase class I and II K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0008890,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016407,GO:0016408,GO:0016453,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 426.0
MMD2_k127_5125626_2 ABC transporter K01996 - - 0.00000089 51.0
MMD2_k127_5134542_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 2.55e-256 823.0
MMD2_k127_5134542_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.252e-222 721.0
MMD2_k127_5134542_10 Transcription elongation factor Spt5 K02601 - - 0.00000000000000000000000000000000001124 141.0
MMD2_k127_5134542_11 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000003709 133.0
MMD2_k127_5134542_12 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000007789 98.0
MMD2_k127_5134542_13 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000003057 58.0
MMD2_k127_5134542_14 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000032 51.0
MMD2_k127_5134542_2 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 436.0
MMD2_k127_5134542_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 419.0
MMD2_k127_5134542_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 398.0
MMD2_k127_5134542_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 302.0
MMD2_k127_5134542_6 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002182 206.0
MMD2_k127_5134542_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002051 198.0
MMD2_k127_5134542_8 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000001133 203.0
MMD2_k127_5134542_9 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000003116 174.0
MMD2_k127_5151038_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 366.0
MMD2_k127_5151038_1 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001812 271.0
MMD2_k127_5151038_10 4Fe-4S dicluster domain K12143 - - 0.000000000000000000000000000001272 129.0
MMD2_k127_5151038_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000008051 68.0
MMD2_k127_5151038_12 Thioesterase-like superfamily K07107 - - 0.0002323 46.0
MMD2_k127_5151038_2 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000001858 244.0
MMD2_k127_5151038_3 CoB--CoM heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000001458 225.0
MMD2_k127_5151038_4 PFAM respiratory-chain NADH dehydrogenase, subunit 1 - - - 0.0000000000000000000000000000000000000000000000000002966 196.0
MMD2_k127_5151038_5 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000005694 182.0
MMD2_k127_5151038_6 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.00000000000000000000000000000000000000000000001122 179.0
MMD2_k127_5151038_7 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000003561 180.0
MMD2_k127_5151038_8 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000633 144.0
MMD2_k127_5151038_9 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000001861 132.0
MMD2_k127_5163517_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 559.0
MMD2_k127_5163517_1 GTPase of K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 411.0
MMD2_k127_5163517_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000001591 71.0
MMD2_k127_5163517_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00001595 48.0
MMD2_k127_5201467_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01531,K01535 - 3.6.3.2,3.6.3.6 0.0 1048.0
MMD2_k127_5201467_1 alpha beta alpha domain I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 443.0
MMD2_k127_5201467_2 PFAM transferase hexapeptide repeat containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 434.0
MMD2_k127_5201467_3 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 375.0
MMD2_k127_5201467_4 COG0191 Fructose tagatose bisphosphate aldolase K01624,K08302 - 4.1.2.13,4.1.2.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 345.0
MMD2_k127_5201467_5 Glycogen debranching enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000503 245.0
MMD2_k127_5201467_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000003378 143.0
MMD2_k127_5201467_7 Hydrolase - - - 0.0000000711 58.0
MMD2_k127_5220829_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 619.0
MMD2_k127_5220829_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000003981 201.0
MMD2_k127_5220829_2 chorismate mutase K14187 - 1.3.1.12,5.4.99.5 0.0000000000000000000000001314 115.0
MMD2_k127_5238259_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 357.0
MMD2_k127_5238259_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 352.0
MMD2_k127_5238259_2 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 299.0
MMD2_k127_5238259_3 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.0000000000000000000000000000000003759 141.0
MMD2_k127_5238259_4 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000005454 128.0
MMD2_k127_5241058_0 PFAM isocitrate isopropylmalate dehydrogenase K00052 GO:0006082,GO:0006575,GO:0006732,GO:0006793,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016053,GO:0019297,GO:0019298,GO:0019752,GO:0032787,GO:0042398,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000002932 268.0
MMD2_k127_5241058_1 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000001087 192.0
MMD2_k127_5241058_2 PFAM Dimethylmenaquinone methyltransferase - - - 0.0000000000000000000000000000000000006681 148.0
MMD2_k127_5241058_3 - - - - 0.00000001956 58.0
MMD2_k127_5257716_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 302.0
MMD2_k127_5257716_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008146 274.0
MMD2_k127_5257716_10 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0044424,GO:0044464,GO:0071840 - 0.0000000000000001791 84.0
MMD2_k127_5257716_11 binds to the 23S rRNA K02921 - - 0.0000000000000003492 83.0
MMD2_k127_5257716_12 - - - - 0.000001216 50.0
MMD2_k127_5257716_13 Probably involved in the biogenesis of the ribosome K14561 - - 0.0004248 49.0
MMD2_k127_5257716_14 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0008692 46.0
MMD2_k127_5257716_2 ABC-type cobalt transport system ATPase component K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
MMD2_k127_5257716_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002232 254.0
MMD2_k127_5257716_4 PFAM ABC transporter related K16785,K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000007427 244.0
MMD2_k127_5257716_5 Ribosome maturation protein K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000007821 237.0
MMD2_k127_5257716_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000001376 214.0
MMD2_k127_5257716_7 PFAM phosphoesterase, RecJ domain protein - - - 0.00000000000000000000000000000000000000000000007884 181.0
MMD2_k127_5257716_8 PFAM Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000001515 157.0
MMD2_k127_5257716_9 ERCC4 domain K10848 - - 0.0000000000000000000000000000000000005997 148.0
MMD2_k127_5261556_0 COG0455 ATPases involved in chromosome partitioning K03496,K03609 - - 0.000000000000000000000000000000000000000004832 166.0
MMD2_k127_5261556_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000002918 124.0
MMD2_k127_5261556_2 Transcriptional regulator, TrmB - - - 0.000000000000002885 81.0
MMD2_k127_5261556_3 Thermolysin metallopeptidase, catalytic domain K19702 - 3.4.11.24 0.00001814 58.0
MMD2_k127_5261556_4 - - - - 0.00009168 54.0
MMD2_k127_5301369_0 Heat shock 70 kDa protein K04043 - - 1.082e-194 626.0
MMD2_k127_5301369_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 400.0
MMD2_k127_5301369_10 cytochrome c biogenesis protein K06196 - - 0.000000000006186 74.0
MMD2_k127_5301369_11 Conserved protein implicated in secretion - - - 0.0000009396 57.0
MMD2_k127_5301369_2 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 400.0
MMD2_k127_5301369_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006706 392.0
MMD2_k127_5301369_4 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 324.0
MMD2_k127_5301369_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000007119 228.0
MMD2_k127_5301369_6 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000006014 220.0
MMD2_k127_5301369_7 Domain of unknown function (DUF371) K09738 - - 0.000000000000000000000000000008777 125.0
MMD2_k127_5301369_8 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000003461 113.0
MMD2_k127_5301369_9 Fe-S-cluster oxidoreductase K06940 - - 0.00000000000000000000001106 107.0
MMD2_k127_5436700_0 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 273.0
MMD2_k127_5436700_1 Cytochrome C biogenesis protein transmembrane region - - - 0.00007777 55.0
MMD2_k127_5490394_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016874,GO:0016879,GO:0016881,GO:0043774,GO:0044424,GO:0044464 6.3.4.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004795 372.0
MMD2_k127_5490394_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.27,1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 288.0
MMD2_k127_5490394_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000003014 170.0
MMD2_k127_5490394_3 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000002586 169.0
MMD2_k127_5490394_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000002944 69.0
MMD2_k127_5492044_0 Succinyl-CoA synthetase, alpha subunit K02381 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 408.0
MMD2_k127_5492044_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 365.0
MMD2_k127_5492044_2 - - - - 0.000000000001702 73.0
MMD2_k127_5507198_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000001437 262.0
MMD2_k127_5507198_1 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.00000000000000000000000000000000000000005144 158.0
MMD2_k127_5507198_2 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000003059 123.0
MMD2_k127_5507198_3 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.00007871 53.0
MMD2_k127_5533172_0 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 334.0
MMD2_k127_5533172_1 Domain of unknown function (DUF2088) - - - 0.0000000000000004526 81.0
MMD2_k127_5533172_2 M6 family metalloprotease domain protein - - - 0.000005475 57.0
MMD2_k127_5601361_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 7.959e-225 704.0
MMD2_k127_5601361_1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 492.0
MMD2_k127_5601361_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000003658 161.0
MMD2_k127_5601361_3 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000008305 54.0
MMD2_k127_5601361_4 PQQ-like domain - - - 0.00001705 54.0
MMD2_k127_5648958_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.392e-317 1004.0
MMD2_k127_5648958_1 Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit K07151 GO:0003674,GO:0003824,GO:0004576,GO:0004579,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005886,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0008250,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0031984,GO:0032991,GO:0034645,GO:0036211,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043687,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0098796,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990234 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001146 303.0
MMD2_k127_5648958_2 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001338 206.0
MMD2_k127_5648958_3 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000001048 172.0
MMD2_k127_5648958_4 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000005546 159.0
MMD2_k127_5648958_5 Binds to the 23S rRNA K02929 - - 0.000000000000000000000000008018 112.0
MMD2_k127_5648958_6 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001466 76.0
MMD2_k127_5648958_7 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000001075 70.0
MMD2_k127_5648958_8 protein conserved in archaea K09723 - - 0.0000000002111 68.0
MMD2_k127_5665623_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 425.0
MMD2_k127_5665623_1 ATP-grasp domain K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000002223 254.0
MMD2_k127_5665623_2 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000000000000000000000000000000000001064 215.0
MMD2_k127_5665623_3 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000001119 178.0
MMD2_k127_5665623_4 RNase H K03469 - 3.1.26.4 0.000000000000002679 81.0
MMD2_k127_5665623_5 - - - - 0.0000000001335 64.0
MMD2_k127_5665623_6 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000001707 71.0
MMD2_k127_5666835_0 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.525e-198 641.0
MMD2_k127_5666835_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 458.0
MMD2_k127_5666835_2 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002778 259.0
MMD2_k127_5666835_3 c-type cytochrome biogenesis protein CcmF K02198 - - 0.000000000000000000000000000000000000000000000000000000000001688 232.0
MMD2_k127_5666835_4 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000006495 149.0
MMD2_k127_5666835_5 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768,K07151 - 2.4.99.18,5.2.1.8 0.0000000000000000000003374 107.0
MMD2_k127_5666835_6 - K00960 - 2.7.7.6 0.00000000000000001866 82.0
MMD2_k127_5666835_7 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000007014 74.0
MMD2_k127_5666835_8 Acetyltransferase (GNAT) family - - - 0.00001764 55.0
MMD2_k127_5666835_9 Peptidase inhibitor I9 - - - 0.0002675 53.0
MMD2_k127_5709281_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000001058 253.0
MMD2_k127_5709281_1 Uncharacterised ACR (DUF711) K09157 - - 0.000000000000000000000000000000000000000000000000000000000000000000202 244.0
MMD2_k127_5709281_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000000000000000000000000000003298 205.0
MMD2_k127_5709281_3 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.00000000000000000000000003489 111.0
MMD2_k127_5709281_4 - - - - 0.000000008018 62.0
MMD2_k127_5711672_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 291.0
MMD2_k127_5711672_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000006109 133.0
MMD2_k127_5711672_2 PFAM Translin K07477 - - 0.000000000000000000000000000001858 128.0
MMD2_k127_5715976_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 365.0
MMD2_k127_5715976_1 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000000000004113 214.0
MMD2_k127_5715976_10 sulfur carrier activity - - - 0.000000000000002484 78.0
MMD2_k127_5715976_11 PFAM thioesterase superfamily K07107 - - 0.000000000002812 73.0
MMD2_k127_5715976_12 Transcriptional regulator K07108 - - 0.00000000004992 67.0
MMD2_k127_5715976_13 PFAM Nitrate reductase gamma subunit - - - 0.0000000001766 65.0
MMD2_k127_5715976_14 methylmalonyl-CoA K01849 - 5.4.99.2 0.000000101 59.0
MMD2_k127_5715976_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000001304 218.0
MMD2_k127_5715976_3 bis(5'-adenosyl)-triphosphatase activity K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.00000000000000000000000000000000000000000000000002109 183.0
MMD2_k127_5715976_4 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000001471 167.0
MMD2_k127_5715976_5 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000001641 173.0
MMD2_k127_5715976_6 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000000000000001196 170.0
MMD2_k127_5715976_7 Glycoprotease family - - - 0.00000000000000000000000000638 118.0
MMD2_k127_5715976_8 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000002297 112.0
MMD2_k127_5715976_9 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain - - - 0.0000000000000000003774 89.0
MMD2_k127_5717225_0 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 475.0
MMD2_k127_5717225_1 COG0607 Rhodanese-related sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 312.0
MMD2_k127_5717225_2 3-hydroxyisobutyrate dehydrogenase - - - 0.00000000000000000000000000000000000005352 149.0
MMD2_k127_5717225_3 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000001096 127.0
MMD2_k127_5786149_0 4Fe-4S single cluster domain K06937 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
MMD2_k127_5786149_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 422.0
MMD2_k127_5786149_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005738 278.0
MMD2_k127_5786149_3 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000003216 248.0
MMD2_k127_5786149_4 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000001682 240.0
MMD2_k127_5786149_5 Belongs to the ComB family K05979 GO:0003674,GO:0003824,GO:0016829,GO:0016830,GO:0016831,GO:0050545 3.1.3.71 0.00000000000000000000000000000000000001376 153.0
MMD2_k127_5786149_6 transcriptional regulator PadR family K10947 - - 0.00000000000001948 77.0
MMD2_k127_5786149_7 Signal peptidase complex catalytic subunit K13280 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005787,GO:0005789,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0012505,GO:0016020,GO:0016485,GO:0016787,GO:0019538,GO:0031090,GO:0031984,GO:0032991,GO:0034641,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0051604,GO:0071704,GO:0098796,GO:0098827,GO:0140096,GO:1901564,GO:1902494,GO:1905368 3.4.21.89 0.00000000005968 71.0
MMD2_k127_5801981_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 383.0
MMD2_k127_5801981_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004293 371.0
MMD2_k127_5801981_2 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004756 324.0
MMD2_k127_5801981_3 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000004026 192.0
MMD2_k127_5801981_4 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000009889 169.0
MMD2_k127_5801981_5 Ribosomal S13/S15 N-terminal domain K02953 GO:0000462,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0030684,GO:0030686,GO:0031974,GO:0031981,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070181,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000003096 131.0
MMD2_k127_5807089_0 Starch synthase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 411.0
MMD2_k127_5807089_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008856 267.0
MMD2_k127_5807089_2 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.0000000000000000000000000003414 120.0
MMD2_k127_5807089_3 PFAM response regulator receiver K07657 - - 0.000000000000000000000001498 119.0
MMD2_k127_5862084_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001972 229.0
MMD2_k127_5862084_1 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000002879 98.0
MMD2_k127_5862084_2 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.00000000000000003662 87.0
MMD2_k127_5862084_3 Acetyltransferase (GNAT) family - - - 0.00006179 51.0
MMD2_k127_5917174_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 468.0
MMD2_k127_5917174_1 Radical SAM superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 458.0
MMD2_k127_5917174_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004953 263.0
MMD2_k127_5939007_0 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 - 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 388.0
MMD2_k127_5939007_1 Protein of unknown function (DUF2961) K14109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 308.0
MMD2_k127_5939007_2 Belongs to the carbohydrate kinase PfkB family K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004871 282.0
MMD2_k127_5939007_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001587 244.0
MMD2_k127_5939007_4 Glycinamide ribonucleotide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000003588 241.0
MMD2_k127_5995973_0 SMART Elongator protein 3 MiaB NifB K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008309 505.0
MMD2_k127_5995973_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006973 430.0
MMD2_k127_5995973_2 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 313.0
MMD2_k127_5995973_3 glutaminyl-peptide cyclotransferase (glutaminyl cyclase) K00683 - - - 0.0000009226 53.0
MMD2_k127_6006443_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 366.0
MMD2_k127_6006443_1 Phosphoesterase family K01114 - 3.1.4.3 0.00000000000000000000000000000000000000000000000000000000000002377 234.0
MMD2_k127_6006443_2 - - - - 0.00000000000000000000000000000000000000000000000000000000001169 218.0
MMD2_k127_6006443_3 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.000000000000000007832 84.0
MMD2_k127_6006443_4 PAC2 family K07159 - - 0.0000000171 63.0
MMD2_k127_6098372_0 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 2.188e-202 641.0
MMD2_k127_6098372_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007146 327.0
MMD2_k127_6098372_10 regulatory protein, arsR - - - 0.0000000006324 66.0
MMD2_k127_6098372_11 Binds the lower part of the 30S subunit head K02982 GO:0000702,GO:0002181,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003735,GO:0003824,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006259,GO:0006281,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008534,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0006524 42.0
MMD2_k127_6098372_2 50S ribosomal protein L4 K02930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003022 263.0
MMD2_k127_6098372_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001237 258.0
MMD2_k127_6098372_4 Putative RNA methyltransferase K09142 - - 0.00000000000000000000000000000000000000000000000000001573 200.0
MMD2_k127_6098372_5 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000001251 200.0
MMD2_k127_6098372_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000002867 164.0
MMD2_k127_6098372_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000843 152.0
MMD2_k127_6098372_8 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000003573 118.0
MMD2_k127_6098372_9 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000006792 97.0
MMD2_k127_6147765_0 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005681 389.0
MMD2_k127_6164159_0 DNA polymerase IV (family X) K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 601.0
MMD2_k127_6164159_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000004535 75.0
MMD2_k127_6277791_0 PFAM CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 462.0
MMD2_k127_6277791_1 Molybdopterin guanine dinucleotide synthesis protein B K03753,K13818 - 2.7.7.77 0.0000000000000167 80.0
MMD2_k127_6277791_2 PFAM peptidase U32 K08303 - - 0.0000000000001284 74.0
MMD2_k127_657537_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 1.71e-238 751.0
MMD2_k127_657537_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 4.628e-224 701.0
MMD2_k127_657537_2 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 351.0
MMD2_k127_657537_3 Peptidase dimerisation domain K21613 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 351.0
MMD2_k127_657537_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000006695 161.0
MMD2_k127_657537_5 PFAM 4Fe-4S ferredoxin - - - 0.000000000000129 73.0
MMD2_k127_657537_6 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000003183 64.0
MMD2_k127_657537_7 Transcriptional regulator K22206 - - 0.000000006103 63.0
MMD2_k127_657537_8 PRC-barrel domain - - - 0.0004135 46.0
MMD2_k127_785259_0 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 398.0
MMD2_k127_785259_1 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000006155 119.0
MMD2_k127_785259_2 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.0000000000000000000001754 101.0
MMD2_k127_785259_3 Hexapeptide repeat of succinyl-transferase K00661 - 2.3.1.79 0.000000000000000002779 90.0
MMD2_k127_785259_4 Polysaccharide deacetylase K22278 - 3.5.1.104 0.000000006631 66.0
MMD2_k127_797923_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 6.802e-239 750.0
MMD2_k127_797923_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 495.0
MMD2_k127_797923_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000005865 160.0
MMD2_k127_797923_3 Domain of unknown function (DUF1610) K07580 - - 0.00000000000000001339 89.0
MMD2_k127_797923_4 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000006227 74.0
MMD2_k127_811038_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001098 267.0
MMD2_k127_811038_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.00000000000000000000000000000000000000000000000000001202 196.0
MMD2_k127_811038_2 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000006194 193.0
MMD2_k127_811038_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000001314 166.0
MMD2_k127_811038_4 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.0000000000000000000000000000000000000001608 157.0
MMD2_k127_811038_5 Uncharacterized protein conserved in archaea (DUF2110) - - - 0.000000000000000000000000000000001026 139.0
MMD2_k127_839612_0 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004956 420.0
MMD2_k127_839612_1 acetyl coenzyme A synthetase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 358.0
MMD2_k127_839612_2 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001603 262.0
MMD2_k127_839612_3 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000006509 126.0
MMD2_k127_839612_4 4Fe-4S binding domain - - - 0.000000000000000000000000295 119.0
MMD2_k127_839612_5 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000001214 111.0
MMD2_k127_846465_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006859 584.0
MMD2_k127_846465_1 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01535 - 3.6.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 477.0
MMD2_k127_846465_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000004516 242.0
MMD2_k127_846465_3 PP-loop family - - - 0.0000000000000000000000000000000000000000000000000000000001647 211.0
MMD2_k127_846465_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000005092 139.0
MMD2_k127_883491_0 Participates in initiation and elongation during chromosome replication - - - 0.0000000000000000000000000000000000001229 165.0
MMD2_k127_883491_1 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000002166 146.0
MMD2_k127_883491_2 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000000000002291 121.0
MMD2_k127_888097_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 1.326e-212 673.0
MMD2_k127_888097_1 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 1.496e-209 664.0
MMD2_k127_888097_10 snRNP Sm proteins K04796 - - 0.00000000000000000000005058 102.0
MMD2_k127_888097_11 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000003958 102.0
MMD2_k127_888097_12 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000008221 93.0
MMD2_k127_888097_2 Beta-Casp domain K07041 - - 4.204e-208 664.0
MMD2_k127_888097_3 ERCC4 domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 392.0
MMD2_k127_888097_4 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001811 221.0
MMD2_k127_888097_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000009548 213.0
MMD2_k127_888097_6 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000004644 212.0
MMD2_k127_888097_7 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000004557 205.0
MMD2_k127_888097_8 PFAM Metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000007652 150.0
MMD2_k127_888097_9 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000004314 105.0
MMD2_k127_909465_0 Uncharacterised protein family (UPF0182) K09118 - - 2.874e-274 872.0
MMD2_k127_909465_1 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000003647 225.0
MMD2_k127_909465_2 CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0009987,GO:0016043,GO:0022607,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071840 - 0.000000000000000000000000001618 115.0
MMD2_k127_909465_3 metal-dependent protease of the PAD1 JAB1 superfamily K20110 - 3.4.19.15 0.000000000000000006679 89.0
MMD2_k127_909465_4 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000008522 78.0
MMD2_k127_909465_5 - - - - 0.00000001255 62.0
MMD2_k127_932406_0 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 293.0
MMD2_k127_932406_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000001085 219.0
MMD2_k127_932406_2 transferase activity, transferring glycosyl groups K01365,K14475 - 3.4.22.15 0.000000000000000000000000000000000000000000000000000000000231 218.0
MMD2_k127_957544_0 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 362.0
MMD2_k127_957544_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 350.0