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Overview

ID MAG02365
Name MMD2_bin.3
Sample SMP0059
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order RBG-13-53-26
Family RBG-13-53-26
Genus JAFGCL01
Species
Assembly information
Completeness (%) 78.14
Contamination (%) 4.06
GC content (%) 58.0
N50 (bp) 8,796
Genome size (bp) 2,200,450

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1982

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1001064_0 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000001077 214.0
MMD2_k127_1001064_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000009974 104.0
MMD2_k127_1001064_2 Short C-terminal domain K08982 - - 0.0000000003595 63.0
MMD2_k127_1016444_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 295.0
MMD2_k127_1016444_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000001507 224.0
MMD2_k127_1016444_2 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000005709 188.0
MMD2_k127_1020364_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 350.0
MMD2_k127_1020364_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004812 312.0
MMD2_k127_1020364_2 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001348 260.0
MMD2_k127_1020364_3 acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000003779 230.0
MMD2_k127_1020364_4 histone deacetylase K04768 - - 0.0000000000000000000000000000000000000000000000000007538 192.0
MMD2_k127_1020364_5 heat shock protein DnaJ domain protein K03686,K05516 - - 0.0000000000000000000000000000000593 134.0
MMD2_k127_1020364_6 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.0000000000000000000000000269 113.0
MMD2_k127_1020364_7 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000002396 85.0
MMD2_k127_1020364_8 N-terminal half of MaoC dehydratase - - - 0.000000002731 64.0
MMD2_k127_1039610_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 406.0
MMD2_k127_1039610_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 361.0
MMD2_k127_1039610_2 PBP superfamily domain K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 304.0
MMD2_k127_1039610_3 Plays a role in the regulation of phosphate uptake K02039 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005102 298.0
MMD2_k127_1039610_4 Uncharacterised protein family (UPF0236) - - - 0.00000000000000000000000000000000000000000000000000000000002013 224.0
MMD2_k127_1040493_0 Glycine radical K00656 - 2.3.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 602.0
MMD2_k127_1040493_1 Thiamine pyrophosphate enzyme, central domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 469.0
MMD2_k127_1040493_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 297.0
MMD2_k127_1040493_3 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000378 251.0
MMD2_k127_1040493_4 Rhomboid family - - - 0.0000000000000000000000000000000000000001373 157.0
MMD2_k127_1040493_5 Glucose dehydrogenase C-terminus K00004 - 1.1.1.303,1.1.1.4 0.00000000000000000000000000001301 121.0
MMD2_k127_1040493_6 - - - - 0.00009527 48.0
MMD2_k127_1058143_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.845e-277 869.0
MMD2_k127_1058143_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002241 258.0
MMD2_k127_1058143_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000006038 187.0
MMD2_k127_1058143_3 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001205 175.0
MMD2_k127_1058143_4 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000001231 160.0
MMD2_k127_1073298_0 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 339.0
MMD2_k127_1073298_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 311.0
MMD2_k127_1073298_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002129 280.0
MMD2_k127_1073298_3 - - - - 0.0000000000000000000000000000007615 124.0
MMD2_k127_1073298_4 Enoyl-(Acyl carrier protein) reductase K18009 - 1.1.1.304,1.1.1.76 0.00000000000000000005439 93.0
MMD2_k127_1073637_0 Aminotransferase class-V K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 469.0
MMD2_k127_1073637_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 465.0
MMD2_k127_1073637_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000005867 161.0
MMD2_k127_1073637_3 DsrE/DsrF-like family K04085 - - 0.00000000000000000000000000000000000002949 148.0
MMD2_k127_1073637_4 Cell wall-active antibiotics response 4TMS YvqF - - - 0.000000001133 64.0
MMD2_k127_1073637_5 RND superfamily drug exporter K06994 - - 0.0008731 44.0
MMD2_k127_1099606_0 choline dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 431.0
MMD2_k127_1099606_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 419.0
MMD2_k127_1099606_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 353.0
MMD2_k127_1099606_3 electron transfer activity K00335,K02572,K03616 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 317.0
MMD2_k127_1099606_4 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002806 248.0
MMD2_k127_1099606_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000002013 92.0
MMD2_k127_1099606_6 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000106 62.0
MMD2_k127_1121411_0 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 402.0
MMD2_k127_1121411_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008898 363.0
MMD2_k127_1121411_10 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000000000001355 230.0
MMD2_k127_1121411_11 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000885 222.0
MMD2_k127_1121411_12 COG1247 Sortase and related acyltransferases K03823 - 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000262 210.0
MMD2_k127_1121411_13 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000000001782 202.0
MMD2_k127_1121411_14 NADPH-quinone reductase (modulator of drug activity B) K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000001456 198.0
MMD2_k127_1121411_15 Domain of unknown function (DU1801) - - - 0.00000000000000000000000000000000000000000000000002023 182.0
MMD2_k127_1121411_16 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000000000000000000522 179.0
MMD2_k127_1121411_17 Methyltransferase - - - 0.00000000000000000000000000000000000000000000003456 178.0
MMD2_k127_1121411_18 FR47-like protein - - - 0.00000000000000000000000000000000000000000000007078 173.0
MMD2_k127_1121411_19 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000004334 171.0
MMD2_k127_1121411_2 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 361.0
MMD2_k127_1121411_20 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000005575 161.0
MMD2_k127_1121411_21 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000187 157.0
MMD2_k127_1121411_22 Universal stress protein family - - - 0.00000000000000000000000000000000000009448 146.0
MMD2_k127_1121411_23 FMN binding - - - 0.00000000000000000000000000009277 122.0
MMD2_k127_1121411_24 nodulation - - - 0.0000000000000000000000000007214 121.0
MMD2_k127_1121411_25 - - - - 0.000000000000000000000000001367 124.0
MMD2_k127_1121411_26 Protein of unknown function (DUF1698) - - - 0.0000000000002041 80.0
MMD2_k127_1121411_27 - - - - 0.000001946 57.0
MMD2_k127_1121411_28 O-methyltransferase activity - - - 0.0007293 49.0
MMD2_k127_1121411_3 Prephenate dehydratase K04518 - 4.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007542 295.0
MMD2_k127_1121411_4 PFAM Glycoside hydrolase 15-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 296.0
MMD2_k127_1121411_5 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001515 286.0
MMD2_k127_1121411_6 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000001043 266.0
MMD2_k127_1121411_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001241 245.0
MMD2_k127_1121411_8 PFAM Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000407 230.0
MMD2_k127_1121411_9 Copper amine oxidase N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004665 232.0
MMD2_k127_1123167_0 helix_turn_helix, Lux Regulon K03556 - - 8.39e-214 694.0
MMD2_k127_1123167_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008111 454.0
MMD2_k127_1123167_10 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000000005602 155.0
MMD2_k127_1123167_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000001261 89.0
MMD2_k127_1123167_12 Wd-40 repeat - - - 0.000000000007872 72.0
MMD2_k127_1123167_13 Psort location Cytoplasmic, score - - - 0.0006108 48.0
MMD2_k127_1123167_15 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.0009163 43.0
MMD2_k127_1123167_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005452 435.0
MMD2_k127_1123167_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 404.0
MMD2_k127_1123167_4 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 319.0
MMD2_k127_1123167_5 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000004672 227.0
MMD2_k127_1123167_6 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000193 233.0
MMD2_k127_1123167_7 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000002716 213.0
MMD2_k127_1123167_8 Dual specificity phosphatase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000003414 214.0
MMD2_k127_1123167_9 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000004895 188.0
MMD2_k127_1124172_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 524.0
MMD2_k127_1124172_1 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000806 251.0
MMD2_k127_1124172_10 - - - - 0.0000000000000000000000002948 110.0
MMD2_k127_1124172_11 marr family - - - 0.000000002972 65.0
MMD2_k127_1124172_12 ABC transporter (Permease) K01992 - - 0.0001518 52.0
MMD2_k127_1124172_2 protein histidine kinase activity K07645 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000007159 253.0
MMD2_k127_1124172_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001034 247.0
MMD2_k127_1124172_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000003976 234.0
MMD2_k127_1124172_5 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000009817 224.0
MMD2_k127_1124172_6 - - - - 0.000000000000000000000000000000000000000000000000009408 184.0
MMD2_k127_1124172_7 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000003916 183.0
MMD2_k127_1124172_8 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000007969 165.0
MMD2_k127_1124172_9 Cytochrome b5-like Heme/Steroid binding domain - - - 0.00000000000000000000000000000000001811 144.0
MMD2_k127_114910_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001548 288.0
MMD2_k127_114910_1 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000001021 116.0
MMD2_k127_114910_2 Dodecin K09165 - - 0.000000000000000000001394 96.0
MMD2_k127_114910_3 Collagen triple helix repeat (20 copies) - - - 0.0000000008738 68.0
MMD2_k127_114910_4 - - - - 0.000000006342 57.0
MMD2_k127_114910_5 - - - - 0.0000000817 54.0
MMD2_k127_115543_0 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005251 583.0
MMD2_k127_115543_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 546.0
MMD2_k127_115543_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 479.0
MMD2_k127_115543_3 Dak1_2 K07030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 339.0
MMD2_k127_115543_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000008195 91.0
MMD2_k127_115543_5 Ribosomal L28 family K02902 - - 0.00000000000000001338 83.0
MMD2_k127_115543_6 - - - - 0.000002665 55.0
MMD2_k127_115543_7 Aminotransferase class-III - - - 0.00002856 46.0
MMD2_k127_1236553_0 Domain of unknown function (DUF4131) K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 402.0
MMD2_k127_1236553_1 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000001815 231.0
MMD2_k127_1236553_2 SLBB domain K02237 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000002455 109.0
MMD2_k127_1252674_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 552.0
MMD2_k127_1252674_1 lipid-transfer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 295.0
MMD2_k127_1252674_2 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 289.0
MMD2_k127_1252674_3 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000002269 236.0
MMD2_k127_1252674_4 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000321 106.0
MMD2_k127_1252674_5 Protein of unknown function (DUF1284) K09706 - - 0.00000000567 62.0
MMD2_k127_1294693_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 2.381e-319 999.0
MMD2_k127_1294693_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 1.425e-237 745.0
MMD2_k127_1294693_10 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000006945 198.0
MMD2_k127_1294693_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001338 184.0
MMD2_k127_1294693_12 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 0.000000000000002055 78.0
MMD2_k127_1294693_13 Recombinase zinc beta ribbon domain - - - 0.0000007104 57.0
MMD2_k127_1294693_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 4.322e-202 636.0
MMD2_k127_1294693_3 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 580.0
MMD2_k127_1294693_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 567.0
MMD2_k127_1294693_5 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004039 356.0
MMD2_k127_1294693_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 300.0
MMD2_k127_1294693_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002517 278.0
MMD2_k127_1294693_8 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000003458 198.0
MMD2_k127_1294693_9 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000003709 197.0
MMD2_k127_1295036_0 AcrB/AcrD/AcrF family K03296 - - 2.543e-214 701.0
MMD2_k127_1295036_1 all-trans-retinol 13,14-reductase activity K09516 - 1.3.99.23 4.303e-213 670.0
MMD2_k127_1295036_10 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000008835 171.0
MMD2_k127_1295036_11 FabA-like domain K02372 - 4.2.1.59 0.000000000000000000000000000000000001277 149.0
MMD2_k127_1295036_12 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000000000000001056 135.0
MMD2_k127_1295036_13 Phosphopantetheine attachment site - - - 0.000000000000000000000000002276 112.0
MMD2_k127_1295036_14 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000197 114.0
MMD2_k127_1295036_2 3-oxoacyl-[acyl-carrier-protein] synthase activity K00646,K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 586.0
MMD2_k127_1295036_3 all-trans-retinol 13,14-reductase activity K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 509.0
MMD2_k127_1295036_4 beta-ketoacyl-acyl-carrier-protein synthase III activity K00648,K22317 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 361.0
MMD2_k127_1295036_5 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 336.0
MMD2_k127_1295036_6 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 306.0
MMD2_k127_1295036_7 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000000000000000000002435 235.0
MMD2_k127_1295036_8 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000002868 239.0
MMD2_k127_1295036_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000003378 225.0
MMD2_k127_1319000_0 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 452.0
MMD2_k127_1319000_1 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 341.0
MMD2_k127_1319000_2 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000143 282.0
MMD2_k127_132063_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005048 589.0
MMD2_k127_132063_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 496.0
MMD2_k127_132063_10 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000006926 228.0
MMD2_k127_132063_11 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000001158 203.0
MMD2_k127_132063_12 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000000000000000000001163 207.0
MMD2_k127_132063_13 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000001234 196.0
MMD2_k127_132063_14 NIL - - - 0.0000000000000000000000000000000000000000000000000005252 186.0
MMD2_k127_132063_15 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000001944 186.0
MMD2_k127_132063_16 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001735 166.0
MMD2_k127_132063_17 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000001886 141.0
MMD2_k127_132063_18 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000001591 109.0
MMD2_k127_132063_19 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000008083 103.0
MMD2_k127_132063_2 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008052 436.0
MMD2_k127_132063_20 pfam yhs - - - 0.00000000000001334 76.0
MMD2_k127_132063_21 O-Antigen ligase K18814 - - 0.000001013 61.0
MMD2_k127_132063_3 PFAM ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 341.0
MMD2_k127_132063_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0043919,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 335.0
MMD2_k127_132063_5 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003222 330.0
MMD2_k127_132063_6 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 328.0
MMD2_k127_132063_7 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 298.0
MMD2_k127_132063_8 COG1230 Co Zn Cd efflux system component K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003498 271.0
MMD2_k127_132063_9 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001365 260.0
MMD2_k127_1350416_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.15e-255 797.0
MMD2_k127_1350416_1 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 501.0
MMD2_k127_1350416_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 453.0
MMD2_k127_1350416_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 317.0
MMD2_k127_1350416_4 histidine kinase A domain protein - - - 0.000000000000000000000000000000006721 137.0
MMD2_k127_1350416_5 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000004415 100.0
MMD2_k127_1370559_0 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13328 - 1.17.1.1,4.2.1.164 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 430.0
MMD2_k127_1370559_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 409.0
MMD2_k127_1370559_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 350.0
MMD2_k127_1370559_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000007095 231.0
MMD2_k127_1370559_4 SIS domain K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000001903 200.0
MMD2_k127_1370559_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000001913 197.0
MMD2_k127_1370559_6 TIGRFAM D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000004362 176.0
MMD2_k127_1370559_7 Yip1 domain - - - 0.000000004662 65.0
MMD2_k127_138517_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 5.172e-250 794.0
MMD2_k127_138517_1 Elongation factor G C-terminus K06207 - - 0.00000000000000000000000000000000000000000000000000000002251 199.0
MMD2_k127_142228_0 HELICc2 K03722 - 3.6.4.12 9.983e-234 754.0
MMD2_k127_142228_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.032e-206 666.0
MMD2_k127_142228_10 NYN domain - - - 0.000000000000000000000000000000000000000004341 162.0
MMD2_k127_142228_11 Acyl-CoA synthetase (NDP forming) - - - 0.000000000000000000000000000000000000009904 151.0
MMD2_k127_142228_12 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000003959 140.0
MMD2_k127_142228_13 ligase activity - - - 0.000000000000000000000000000000005437 142.0
MMD2_k127_142228_14 Phosphoglycerate mutase family - - - 0.0000000000000000000000000001422 123.0
MMD2_k127_142228_15 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000001393 103.0
MMD2_k127_142228_17 helix_turn_helix multiple antibiotic resistance protein K06075 - - 0.000000002078 65.0
MMD2_k127_142228_2 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 498.0
MMD2_k127_142228_3 Domain of unknown function (DUF1998) K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 488.0
MMD2_k127_142228_4 Poly A polymerase head domain K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 319.0
MMD2_k127_142228_5 TIGRFAM UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 309.0
MMD2_k127_142228_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003602 282.0
MMD2_k127_142228_7 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000003173 224.0
MMD2_k127_142228_8 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000000000000702 201.0
MMD2_k127_142228_9 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000002078 183.0
MMD2_k127_1436757_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 1.309e-194 613.0
MMD2_k127_1436757_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 389.0
MMD2_k127_1436757_2 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000806 283.0
MMD2_k127_1436757_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000009856 217.0
MMD2_k127_1465532_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 618.0
MMD2_k127_1465532_1 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 287.0
MMD2_k127_1562963_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 557.0
MMD2_k127_1562963_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 432.0
MMD2_k127_1562963_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000008463 188.0
MMD2_k127_1562963_3 ERG2 and Sigma1 receptor like protein K20719 - - 0.0000000000000000000000000000000000000000001377 166.0
MMD2_k127_1573320_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005787 262.0
MMD2_k127_1573320_1 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000001576 192.0
MMD2_k127_1573320_2 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.0000000000000000000000001263 108.0
MMD2_k127_1573320_3 UDP-3-O- 3-hydroxymyristoyl glucosamine N-acyltransferase - - - 0.00002297 56.0
MMD2_k127_1574293_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 1.357e-206 664.0
MMD2_k127_1574293_1 PFAM formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 629.0
MMD2_k127_1582931_0 GMC oxidoreductase - - - 3.507e-227 715.0
MMD2_k127_1582931_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 518.0
MMD2_k127_1582931_2 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 440.0
MMD2_k127_1582931_3 PFAM AMP-dependent synthetase and ligase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 404.0
MMD2_k127_1582931_4 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 316.0
MMD2_k127_1582931_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002308 242.0
MMD2_k127_1582931_6 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000002968 212.0
MMD2_k127_1582931_7 PFAM Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000008888 93.0
MMD2_k127_1582931_8 TAP-like protein - - - 0.0001428 50.0
MMD2_k127_1584380_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000002891 109.0
MMD2_k127_1584380_1 Belongs to the universal stress protein A family - - - 0.0000000000000000000003856 102.0
MMD2_k127_1584380_2 - - - - 0.0000008936 61.0
MMD2_k127_1584380_3 Cellulosome anchoring protein cohesin region - - - 0.000001509 57.0
MMD2_k127_1606671_0 NAD(P)-binding Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 383.0
MMD2_k127_1606671_1 Recombinase zinc beta ribbon domain - - - 0.000000000000000000000000000000000000000000000000000000000000007029 222.0
MMD2_k127_1606671_2 short-chain dehydrogenase K07124 - - 0.0000000000000000000000000000000000000000000000000000001001 209.0
MMD2_k127_1606671_3 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000002375 187.0
MMD2_k127_1606671_4 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000002577 184.0
MMD2_k127_1606671_5 Thioesterase superfamily - - - 0.000000000000000000000002759 107.0
MMD2_k127_1606671_6 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000001596 100.0
MMD2_k127_1606671_7 COG3631 Ketosteroid isomerase-related protein - - - 0.000000000000000006992 91.0
MMD2_k127_1620927_0 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000001356 235.0
MMD2_k127_1620927_1 PFAM Acetoacetate decarboxylase (ADC) - - - 0.0000000000000000000000000000000000000000000003289 177.0
MMD2_k127_1620927_2 PFAM Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000001011 133.0
MMD2_k127_1620927_3 light absorption - - - 0.000000000000000000002507 98.0
MMD2_k127_1620927_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.0000000000000000004914 97.0
MMD2_k127_1620927_5 - - - - 0.0000000000000003113 85.0
MMD2_k127_1620927_6 - - - - 0.0000000000001802 80.0
MMD2_k127_1624588_0 SPFH domain / Band 7 family - - - 1.846e-203 646.0
MMD2_k127_1626883_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 1.191e-224 704.0
MMD2_k127_1626883_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K00193,K14138 - 2.3.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 519.0
MMD2_k127_1626883_2 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000003571 201.0
MMD2_k127_1626883_3 PFAM CO dehydrogenase beta subunit acetyl-CoA synthase epsilon subunit K00195,K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000003381 185.0
MMD2_k127_1630249_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 3.055e-244 778.0
MMD2_k127_1630249_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000725 597.0
MMD2_k127_1630249_10 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000004079 214.0
MMD2_k127_1630249_11 - - - - 0.00000000000000000000000000000000000000000000000000000003704 204.0
MMD2_k127_1630249_12 Psort location Cytoplasmic, score 9.98 K00334 - 1.6.5.3 0.00000000000000000000000000000001907 130.0
MMD2_k127_1630249_13 Modulates RecA activity K03565 - - 0.00000000000000000000000000000005099 130.0
MMD2_k127_1630249_14 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000002923 111.0
MMD2_k127_1630249_15 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000007429 87.0
MMD2_k127_1630249_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 456.0
MMD2_k127_1630249_3 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 422.0
MMD2_k127_1630249_4 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 368.0
MMD2_k127_1630249_5 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 315.0
MMD2_k127_1630249_6 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009183 286.0
MMD2_k127_1630249_7 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000005904 269.0
MMD2_k127_1630249_8 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008163 263.0
MMD2_k127_1630249_9 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000002726 227.0
MMD2_k127_1640293_0 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 374.0
MMD2_k127_1640293_1 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000002961 256.0
MMD2_k127_1640293_2 4Fe-4S dicluster domain K00124,K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000005845 233.0
MMD2_k127_1640293_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000006697 199.0
MMD2_k127_1640293_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 0.00000000000000000000000000000000000000003049 156.0
MMD2_k127_1640293_5 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000000005677 129.0
MMD2_k127_1640293_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000002835 115.0
MMD2_k127_1640293_7 lactoylglutathione lyase activity - - - 0.000000000000000000006794 100.0
MMD2_k127_1640293_8 CoA-binding protein K06929 - - 0.000000000000000002259 86.0
MMD2_k127_165312_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 5e-214 678.0
MMD2_k127_165312_1 Binding-protein-dependent transport system inner membrane component K15581 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 467.0
MMD2_k127_165312_10 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000004335 193.0
MMD2_k127_165312_11 Bacterial lipid A biosynthesis acyltransferase K02517,K22311 - 2.3.1.241,2.3.1.265 0.000000000000000000000000000000000000000000000006057 184.0
MMD2_k127_165312_12 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000004134 175.0
MMD2_k127_165312_13 FAD dependent oxidoreductase K07007 - - 0.000000000000000000000000000000000000000002909 160.0
MMD2_k127_165312_14 acetyltransferase - - - 0.00000000000881 75.0
MMD2_k127_165312_15 - - - - 0.000004376 55.0
MMD2_k127_165312_16 - - - - 0.0002601 51.0
MMD2_k127_165312_2 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 453.0
MMD2_k127_165312_3 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 452.0
MMD2_k127_165312_4 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 445.0
MMD2_k127_165312_5 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 445.0
MMD2_k127_165312_6 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004105 413.0
MMD2_k127_165312_7 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 364.0
MMD2_k127_165312_8 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 327.0
MMD2_k127_165312_9 Short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000002746 216.0
MMD2_k127_1661611_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000006033 259.0
MMD2_k127_1661611_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000001903 186.0
MMD2_k127_1661611_3 AraC-like ligand binding domain - - - 0.000000000000000000000000000000000000000000544 162.0
MMD2_k127_1661611_4 SnoaL-like domain - - - 0.000000000000000000000000000000000000001547 151.0
MMD2_k127_1661611_5 PFAM Transglutaminase-like - - - 0.0000000000000000000000000000000000226 143.0
MMD2_k127_1661611_6 4Fe-4S dicluster domain - - - 0.000000000000007162 78.0
MMD2_k127_1661611_7 - - - - 0.0000000000007559 69.0
MMD2_k127_1661611_8 Domain of unknown function (DUF4382) - - - 0.00000000000129 77.0
MMD2_k127_1661611_9 - - - - 0.0000001782 63.0
MMD2_k127_1666370_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 372.0
MMD2_k127_1666370_1 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 357.0
MMD2_k127_1666370_2 Type II secretion system (T2SS), protein F K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 357.0
MMD2_k127_1666370_3 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002285 355.0
MMD2_k127_1666370_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.00000000000000000000000002365 110.0
MMD2_k127_1666370_5 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000000243 111.0
MMD2_k127_1731663_0 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000006805 253.0
MMD2_k127_1731663_1 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000001411 251.0
MMD2_k127_1731663_2 KR domain - - - 0.00000000000000000000000000000001627 130.0
MMD2_k127_17422_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002792 256.0
MMD2_k127_17422_1 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000001886 191.0
MMD2_k127_17422_2 AAA domain - - - 0.000000000000000000000000000000004857 135.0
MMD2_k127_1791157_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004853 254.0
MMD2_k127_1791157_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002505 234.0
MMD2_k127_1791157_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000005852 228.0
MMD2_k127_1791157_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000001354 156.0
MMD2_k127_1814463_0 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004178 276.0
MMD2_k127_1814463_1 PFAM ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
MMD2_k127_1814463_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000001211 63.0
MMD2_k127_1814463_3 ABC-2 family transporter protein - - - 0.0004091 51.0
MMD2_k127_1817060_0 metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 408.0
MMD2_k127_1817060_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000002812 188.0
MMD2_k127_1817060_2 cell death in response to hydrogen peroxide K09829,K20719 GO:0000247,GO:0000302,GO:0001653,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004985,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005783,GO:0005886,GO:0005887,GO:0006066,GO:0006629,GO:0006694,GO:0006696,GO:0006950,GO:0006979,GO:0007154,GO:0007165,GO:0007186,GO:0007275,GO:0007399,GO:0008144,GO:0008150,GO:0008152,GO:0008202,GO:0008204,GO:0008219,GO:0008528,GO:0008610,GO:0009058,GO:0009611,GO:0009636,GO:0009987,GO:0010035,GO:0010941,GO:0012505,GO:0014069,GO:0016020,GO:0016021,GO:0016043,GO:0016125,GO:0016126,GO:0016128,GO:0016129,GO:0016853,GO:0016860,GO:0016863,GO:0022607,GO:0023052,GO:0031224,GO:0031226,GO:0031967,GO:0031975,GO:0032279,GO:0032501,GO:0032502,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0036473,GO:0036474,GO:0038003,GO:0038023,GO:0042221,GO:0042493,GO:0042542,GO:0042802,GO:0042981,GO:0043067,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043523,GO:0043933,GO:0044085,GO:0044107,GO:0044108,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044464,GO:0045202,GO:0046165,GO:0046677,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050896,GO:0051259,GO:0051260,GO:0051716,GO:0060089,GO:0065003,GO:0065007,GO:0070206,GO:0070207,GO:0070301,GO:0070887,GO:0071236,GO:0071704,GO:0071840,GO:0071944,GO:0097237,GO:0097384,GO:0097458,GO:0098794,GO:0098984,GO:0099572,GO:1901214,GO:1901360,GO:1901362,GO:1901576,GO:1901615,GO:1901617,GO:1901700,GO:1901701,GO:1902652,GO:1902653 - 0.00000000000000000000003254 103.0
MMD2_k127_1817060_3 - - - - 0.000000009394 63.0
MMD2_k127_1846204_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.094e-197 622.0
MMD2_k127_1846204_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 420.0
MMD2_k127_1846204_2 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003969 258.0
MMD2_k127_1846204_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 GO:0003674,GO:0003824,GO:0004638,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0016853,GO:0016866,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034023,GO:0034641,GO:0034654,GO:0040007,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 5.4.99.18 0.0000000000000000000000000000000000000000000000000001364 189.0
MMD2_k127_1846204_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000011 82.0
MMD2_k127_1846204_5 TIGRFAM geranylgeranyl reductase family - - - 0.00000000000008035 75.0
MMD2_k127_1850009_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 316.0
MMD2_k127_1850009_1 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 309.0
MMD2_k127_1850009_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001521 261.0
MMD2_k127_1850009_3 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007195 256.0
MMD2_k127_1850009_4 PBP superfamily domain K02040 - - 0.00000000000000000000000000000000000000000000001036 177.0
MMD2_k127_1858328_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005481 503.0
MMD2_k127_1858328_1 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 287.0
MMD2_k127_1858328_2 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000001181 213.0
MMD2_k127_1858328_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000001072 108.0
MMD2_k127_1858328_4 Helix-turn-helix XRE-family like proteins K07729 - - 0.000000000000000000001403 96.0
MMD2_k127_1904966_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004744 366.0
MMD2_k127_1904966_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 341.0
MMD2_k127_1904966_2 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 302.0
MMD2_k127_1904966_3 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000001029 215.0
MMD2_k127_1904966_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.000000000000000000000000000000000000000000000000001692 186.0
MMD2_k127_1904966_5 Intracellular protease K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000004817 180.0
MMD2_k127_1904966_6 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.00000000000000000000000000000000000000000611 156.0
MMD2_k127_1904966_7 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000002476 146.0
MMD2_k127_1904966_8 helix_turn_helix, Lux Regulon - - - 0.0000000000000000006938 87.0
MMD2_k127_1908042_0 GH3 auxin-responsive promoter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 421.0
MMD2_k127_1908042_1 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000006907 205.0
MMD2_k127_1908042_2 Protein of unknown function (DUF3068) - - - 0.00005895 54.0
MMD2_k127_1918152_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000001631 208.0
MMD2_k127_1919382_0 helix_turn_helix, Lux Regulon K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002624 293.0
MMD2_k127_1919382_1 - - - - 0.0000000000004809 71.0
MMD2_k127_1920010_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 7.862e-242 754.0
MMD2_k127_1920010_1 Major Facilitator Superfamily K08177 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 347.0
MMD2_k127_1920010_2 Belongs to the UPF0178 family - - - 0.00000000000000000000000000000000000001814 149.0
MMD2_k127_1920010_3 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.0000000000000000002839 91.0
MMD2_k127_1942515_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 280.0
MMD2_k127_1942515_1 Signal transduction histidine kinase - - - 0.000000000000000000000000000000000000000000000003914 199.0
MMD2_k127_1942515_2 Psort location Cytoplasmic, score K02479,K07692 - - 0.000000000000000000000000000000000008651 144.0
MMD2_k127_1942515_3 NAD(P)-binding Rossmann-like domain - - - 0.00000000000000000000003887 100.0
MMD2_k127_1942515_4 helix_turn_helix, Lux Regulon K07689 - - 0.0000000000000005999 83.0
MMD2_k127_1955663_0 BadF BadG BcrA BcrD - - - 4.275e-249 818.0
MMD2_k127_1955663_1 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000002625 208.0
MMD2_k127_1955663_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000004156 196.0
MMD2_k127_1955663_3 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000003313 181.0
MMD2_k127_2005130_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003085 273.0
MMD2_k127_2005130_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004188 258.0
MMD2_k127_2005130_2 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000001141 133.0
MMD2_k127_2005130_3 - - - - 0.000000000001529 73.0
MMD2_k127_2005130_4 PHP domain protein K07053 - 3.1.3.97 0.0000017 58.0
MMD2_k127_2006223_0 MgtE intracellular N domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002998 246.0
MMD2_k127_2006223_1 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000868 251.0
MMD2_k127_2006223_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000001234 214.0
MMD2_k127_2006223_3 Methyltransferase domain K06987 - - 0.0000000000000000000000000000000000000000004589 166.0
MMD2_k127_2006223_4 Fibronectin type 3 domain - - - 0.000000000000000000000000004321 126.0
MMD2_k127_2006223_5 Autotransporter beta-domain - - - 0.00000000000005361 85.0
MMD2_k127_2008931_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 449.0
MMD2_k127_2008931_1 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000001133 143.0
MMD2_k127_2008931_2 Bacterial transferase hexapeptide (six repeats) K02617 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.00000000000000000000000000000000001109 143.0
MMD2_k127_2008931_3 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000004667 113.0
MMD2_k127_2008931_4 N-terminal half of MaoC dehydratase - - - 0.00000000000000000009619 95.0
MMD2_k127_2008931_5 Peptidase family M54 K06974 - - 0.0000000000007462 70.0
MMD2_k127_205916_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 423.0
MMD2_k127_205916_1 PFAM Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001023 222.0
MMD2_k127_205916_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000007437 211.0
MMD2_k127_205916_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0000910,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007049,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0022402,GO:0022607,GO:0032153,GO:0032506,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051258,GO:0051301,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000000006767 159.0
MMD2_k127_205916_4 Family of unknown function (DUF5343) - - - 0.0000000000000000000000005865 114.0
MMD2_k127_205916_5 - - - - 0.000000000003158 72.0
MMD2_k127_206667_0 Belongs to the peptidase S16 family - - - 7.425e-263 831.0
MMD2_k127_206667_1 NADH dehydrogenase K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001755 263.0
MMD2_k127_206667_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334,K18330 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000003694 169.0
MMD2_k127_2068678_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 3.289e-200 651.0
MMD2_k127_2068678_1 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 504.0
MMD2_k127_2068678_2 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005684 291.0
MMD2_k127_2068678_3 COG0500 SAM-dependent methyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004097 275.0
MMD2_k127_2068678_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000003347 267.0
MMD2_k127_2068678_5 - - - - 0.00000000000000001918 85.0
MMD2_k127_2068678_6 Diacylglycerol kinase catalytic domain - - - 0.0000000000000007366 79.0
MMD2_k127_2068678_7 PFAM nitrogen-fixing NifU domain protein - - - 0.0004488 47.0
MMD2_k127_209186_0 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 566.0
MMD2_k127_209186_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00076 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008202,GO:0008206,GO:0008709,GO:0009056,GO:0009987,GO:0016043,GO:0016054,GO:0016229,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022607,GO:0030573,GO:0032787,GO:0033764,GO:0042802,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901360,GO:1901575,GO:1901615 1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 291.0
MMD2_k127_209186_2 arylsulfatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004554 287.0
MMD2_k127_209186_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009184 248.0
MMD2_k127_209186_4 Isochorismatase family - - - 0.00000000000000000000000000003258 124.0
MMD2_k127_209186_6 deoxyhypusine monooxygenase activity - - - 0.000000000000000004486 98.0
MMD2_k127_2097146_0 ligase activity K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000002719 239.0
MMD2_k127_2097146_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000004726 237.0
MMD2_k127_2097146_2 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000002117 196.0
MMD2_k127_2097146_3 Serine aminopeptidase, S33 - - - 0.000000000000000009478 86.0
MMD2_k127_212534_0 Heat shock 70 kDa protein K04043 - - 2.636e-269 837.0
MMD2_k127_212534_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000001884 242.0
MMD2_k127_212534_2 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000001433 193.0
MMD2_k127_212534_3 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000345 149.0
MMD2_k127_2129827_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.711e-243 765.0
MMD2_k127_2129827_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000001121 276.0
MMD2_k127_2129827_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000001775 276.0
MMD2_k127_2129827_3 isomerase B K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000002656 175.0
MMD2_k127_2129827_4 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00003737 50.0
MMD2_k127_2139387_0 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 405.0
MMD2_k127_2139387_1 PFAM Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003854 275.0
MMD2_k127_2139387_2 - - - - 0.000000000000000000017 100.0
MMD2_k127_2139387_3 - - - - 0.00000009682 56.0
MMD2_k127_2170840_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 599.0
MMD2_k127_2170840_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007185 531.0
MMD2_k127_2170840_10 Universal stress protein family - - - 0.0000000000000000001182 94.0
MMD2_k127_2170840_11 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.00000000001647 65.0
MMD2_k127_2170840_2 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 347.0
MMD2_k127_2170840_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004377 278.0
MMD2_k127_2170840_4 PFAM ATPase BadF BadG BcrA BcrD type K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000005905 263.0
MMD2_k127_2170840_5 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000005538 222.0
MMD2_k127_2170840_6 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000003575 227.0
MMD2_k127_2170840_7 PFAM ATPase BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000002849 160.0
MMD2_k127_2170840_8 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000008659 157.0
MMD2_k127_2170840_9 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000001533 123.0
MMD2_k127_2181659_0 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.64e-225 711.0
MMD2_k127_2181659_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 558.0
MMD2_k127_2181659_2 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 442.0
MMD2_k127_2181659_3 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000001624 121.0
MMD2_k127_2201475_0 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 309.0
MMD2_k127_2201475_1 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000626 218.0
MMD2_k127_2201475_2 pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system K02015 - - 0.00000000000000000000000000000000000000000000000000004762 199.0
MMD2_k127_2201475_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000006762 158.0
MMD2_k127_2201475_4 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000001944 149.0
MMD2_k127_2201475_5 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000007466 128.0
MMD2_k127_2201475_6 Helix-turn-helix domain - - - 0.00000000000000000000005565 107.0
MMD2_k127_2201475_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000007518 97.0
MMD2_k127_2201475_8 PFAM periplasmic binding protein K02016 - - 0.00000000005939 74.0
MMD2_k127_2207258_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 420.0
MMD2_k127_2207258_1 Domain of unknown function (DUF4389) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002281 281.0
MMD2_k127_2207258_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000002245 214.0
MMD2_k127_2207258_3 - - - - 0.0000000000000000000000000000000000000000000003581 171.0
MMD2_k127_2207258_4 Protein of unknown function (DUF2089) - - - 0.00000000000000000000000000000000000000007655 153.0
MMD2_k127_2207258_5 - - - - 0.000000000000000000000000001253 118.0
MMD2_k127_2207258_6 Belongs to the transketolase family K00615 - 2.2.1.1 0.00000000000005072 72.0
MMD2_k127_2207258_7 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000006164 81.0
MMD2_k127_2207258_8 - - - - 0.000000001222 59.0
MMD2_k127_2207258_9 - - - - 0.0000228 50.0
MMD2_k127_222463_0 Protein of unknown function (DUF5131) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 319.0
MMD2_k127_222463_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 286.0
MMD2_k127_222463_2 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000001891 175.0
MMD2_k127_222463_3 - - - - 0.000000000000000000000000000004125 120.0
MMD2_k127_222463_4 - - - - 0.00000000000000000000004846 102.0
MMD2_k127_222463_5 - - - - 0.000000000009776 71.0
MMD2_k127_222463_6 Short-chain dehydrogenase reductase Sdr - - - 0.0000000008937 66.0
MMD2_k127_222463_7 Type II/IV secretion system protein K02669 - - 0.00000001974 58.0
MMD2_k127_2238816_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000001936 243.0
MMD2_k127_2238816_1 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000002012 183.0
MMD2_k127_2238816_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000004623 108.0
MMD2_k127_2238816_3 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001715 100.0
MMD2_k127_2238816_4 KH domain K06960 - - 0.00000000000000002917 83.0
MMD2_k127_2238816_5 Pfam SNARE associated Golgi protein - - - 0.0000000000000002347 88.0
MMD2_k127_2290349_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006763 469.0
MMD2_k127_2290349_1 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003704 276.0
MMD2_k127_2290349_2 - - - - 0.00000000000000000001264 104.0
MMD2_k127_2342660_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 474.0
MMD2_k127_2342660_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 465.0
MMD2_k127_2342660_2 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 448.0
MMD2_k127_2342660_3 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 340.0
MMD2_k127_2342660_4 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009719 274.0
MMD2_k127_2342660_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000358 192.0
MMD2_k127_2342660_6 MaoC like domain - - - 0.00000000000000000000000000000000000000000000003168 179.0
MMD2_k127_2342660_7 PFAM Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000007284 154.0
MMD2_k127_2342660_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000001983 131.0
MMD2_k127_2360958_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 316.0
MMD2_k127_2360958_1 CoA-substrate-specific enzyme activase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004859 266.0
MMD2_k127_2360958_2 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001047 270.0
MMD2_k127_2360958_3 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.000000000002467 70.0
MMD2_k127_2364940_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.738e-313 983.0
MMD2_k127_2364940_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 5.724e-199 640.0
MMD2_k127_2364940_10 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000002752 236.0
MMD2_k127_2364940_11 histidine kinase, dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000000000000000001515 227.0
MMD2_k127_2364940_12 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K13832 GO:0000166,GO:0003674,GO:0003824,GO:0003855,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016829,GO:0016835,GO:0016836,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000002155 227.0
MMD2_k127_2364940_13 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000137 236.0
MMD2_k127_2364940_14 Putative sensor - - - 0.000000000000000000000000000000000000000000000000000000000001998 219.0
MMD2_k127_2364940_15 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000004596 231.0
MMD2_k127_2364940_16 COGs COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000003642 186.0
MMD2_k127_2364940_17 NUDIX domain - - - 0.0000000000000000000000000000000000000000000007428 169.0
MMD2_k127_2364940_18 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000000000000000000000000118 156.0
MMD2_k127_2364940_19 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000000000000000000001125 136.0
MMD2_k127_2364940_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 1.058e-198 627.0
MMD2_k127_2364940_20 PadR family transcriptional regulator K10947 - - 0.00000000000000000000000000000000001328 140.0
MMD2_k127_2364940_21 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000001297 138.0
MMD2_k127_2364940_22 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000007746 127.0
MMD2_k127_2364940_23 - - - - 0.000000000000000002679 87.0
MMD2_k127_2364940_24 - - - - 0.000000000000003607 86.0
MMD2_k127_2364940_26 - - - - 0.0000000007844 62.0
MMD2_k127_2364940_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 447.0
MMD2_k127_2364940_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 438.0
MMD2_k127_2364940_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009159 416.0
MMD2_k127_2364940_6 Dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 336.0
MMD2_k127_2364940_7 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002034 299.0
MMD2_k127_2364940_8 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629,K07459 GO:0000731,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0018130,GO:0019438,GO:0031668,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002013 285.0
MMD2_k127_2364940_9 methyltransferase K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000002091 271.0
MMD2_k127_2368341_0 Single Cache domain 2 K02660,K03406,K05875,K05876,K07216,K11525 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000496 297.0
MMD2_k127_2368341_1 Calcineurin-like phosphoesterase - - - 0.000000000000000001481 100.0
MMD2_k127_2400451_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 463.0
MMD2_k127_2400451_1 GTPase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000668 303.0
MMD2_k127_2400451_10 Methyltransferase - - - 0.00000000000002126 83.0
MMD2_k127_2400451_11 PFAM NUDIX hydrolase K07455 - - 0.00000000000104 70.0
MMD2_k127_2400451_12 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase. The precise role of the epsilon subunit is unclear K00195 - - 0.00008545 51.0
MMD2_k127_2400451_13 - - - - 0.0003772 48.0
MMD2_k127_2400451_2 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000491 277.0
MMD2_k127_2400451_3 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000002929 241.0
MMD2_k127_2400451_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000003474 218.0
MMD2_k127_2400451_5 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000436 167.0
MMD2_k127_2400451_6 NUDIX domain - - - 0.00000000000000000000000000000000000000001069 160.0
MMD2_k127_2400451_7 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.000000000000000000000000000000002099 134.0
MMD2_k127_2400451_8 B12 binding domain K01849 - 5.4.99.2 0.000000000000000000000000000000002126 133.0
MMD2_k127_2400451_9 Hydrolase - - - 0.000000000000000000000000000000009083 132.0
MMD2_k127_2401547_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 612.0
MMD2_k127_2401547_1 Membrane - - - 0.0000000000000000000000000000141 128.0
MMD2_k127_2435456_0 FAD linked oxidases, C-terminal domain - - - 0.0 1470.0
MMD2_k127_2435456_1 COG1024 Enoyl-CoA hydratase carnithine racemase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004796 374.0
MMD2_k127_2435456_2 acetyltransferase - - - 0.00000000000000000000000000000000000000000000001826 179.0
MMD2_k127_2435456_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000005432 127.0
MMD2_k127_2435456_5 E-Z type HEAT repeats - - - 0.000000000000000000000000001262 119.0
MMD2_k127_2435456_6 Transcriptional regulator, arsR family - - - 0.0000000000000000000007972 98.0
MMD2_k127_2454743_0 Beta-eliminating lyase K01668 - 4.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 534.0
MMD2_k127_2454743_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 450.0
MMD2_k127_2454743_2 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000887 198.0
MMD2_k127_2454743_3 Transcriptional regulatory protein, C terminal - - - 0.0000000000000007236 89.0
MMD2_k127_2454743_4 Sterol carrier protein - - - 0.000000000007044 76.0
MMD2_k127_246020_0 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000001748 230.0
MMD2_k127_246020_1 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000003653 227.0
MMD2_k127_246020_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000549 98.0
MMD2_k127_2482033_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 357.0
MMD2_k127_2482033_1 cellulose 1,4-beta-cellobiosidase activity - - - 0.000000000000000000000000000000000005543 159.0
MMD2_k127_2482033_2 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000003878 131.0
MMD2_k127_2482033_3 Peptidase, M28 K19702 - 3.4.11.24 0.0006487 51.0
MMD2_k127_2482033_4 restriction endonuclease K07454 - - 0.0008496 48.0
MMD2_k127_2514909_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007138 556.0
MMD2_k127_2514909_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 464.0
MMD2_k127_2514909_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000874 318.0
MMD2_k127_2514909_3 Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000495 274.0
MMD2_k127_2514909_4 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000001984 244.0
MMD2_k127_2514909_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000002918 147.0
MMD2_k127_2514909_6 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000002172 111.0
MMD2_k127_2517729_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 366.0
MMD2_k127_2517729_1 trans-aconitate 2-methyltransferase activity K00598,K02169 - 2.1.1.144,2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 325.0
MMD2_k127_2517729_2 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 319.0
MMD2_k127_2517729_3 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001279 263.0
MMD2_k127_2517729_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000001347 213.0
MMD2_k127_2517729_5 Belongs to the enoyl-CoA hydratase isomerase family K15019 - 4.2.1.116 0.0000000000000000000000000000000000000000000000000000002978 210.0
MMD2_k127_2517729_6 TIGRFAM degV family protein - - - 0.000000000000000000000000000000000000000000000000001071 195.0
MMD2_k127_2517729_7 Protein of unknown function (DUF3795) - - - 0.000000000000000000000000000000001441 134.0
MMD2_k127_2536632_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000605 343.0
MMD2_k127_2536632_1 CheR methyltransferase, SAM binding domain protein K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000005545 250.0
MMD2_k127_2536632_2 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000002209 180.0
MMD2_k127_2536632_3 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains K03413 - - 0.0000000000000000000000000000000000000006992 151.0
MMD2_k127_2536632_4 Deamidates glutamine residues to glutamate on methyl- accepting chemotaxis receptors (MCPs). CheD-mediated MCP deamidation is required for productive communication of the conformational signals of the chemoreceptors to the CheA kinase K03411 - 3.5.1.44 0.0000000000000000003733 91.0
MMD2_k127_2579043_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 532.0
MMD2_k127_2579043_1 FAD binding domain K16051 - 1.3.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 501.0
MMD2_k127_2579043_10 EthD domain - - - 0.000000000000006692 81.0
MMD2_k127_2579043_11 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000223 82.0
MMD2_k127_2579043_12 NAD(P)-binding Rossmann-like domain - - - 0.00000006579 54.0
MMD2_k127_2579043_13 endonuclease activity K07451 - - 0.000007294 54.0
MMD2_k127_2579043_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003113 400.0
MMD2_k127_2579043_3 GDP-mannose 4,6 dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 320.0
MMD2_k127_2579043_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 317.0
MMD2_k127_2579043_5 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000125 291.0
MMD2_k127_2579043_6 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001543 261.0
MMD2_k127_2579043_7 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000005958 234.0
MMD2_k127_2579043_8 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000001473 222.0
MMD2_k127_2579043_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000009654 227.0
MMD2_k127_2585409_0 transcriptional regulator K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000204 257.0
MMD2_k127_2585409_1 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000004534 241.0
MMD2_k127_2585409_2 Pfam:DUF2424 - - - 0.000000000000000000000000000000000000002939 150.0
MMD2_k127_2588140_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 580.0
MMD2_k127_2588140_1 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005277 567.0
MMD2_k127_2588140_10 hydrocarbon binding protein (contains V4R domain) - - - 0.0000000000000000000000000000000000000000000000101 177.0
MMD2_k127_2588140_11 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000742 133.0
MMD2_k127_2588140_12 TFIIE alpha subunit - - - 0.000000000000000000000002502 106.0
MMD2_k127_2588140_13 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.000001078 52.0
MMD2_k127_2588140_2 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 460.0
MMD2_k127_2588140_3 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 418.0
MMD2_k127_2588140_4 Electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 319.0
MMD2_k127_2588140_5 Acyl-CoA dehydrogenase, middle domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 304.0
MMD2_k127_2588140_6 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 298.0
MMD2_k127_2588140_7 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005585 286.0
MMD2_k127_2588140_8 Electron transfer flavoprotein K03521,K22431 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000002668 246.0
MMD2_k127_2588140_9 ACT domain - - - 0.000000000000000000000000000000000000000000000000004005 184.0
MMD2_k127_2592627_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 357.0
MMD2_k127_2592627_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003549 275.0
MMD2_k127_2592627_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004291 244.0
MMD2_k127_2615659_0 PFAM formate C-acetyltransferase glycine radical K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1034.0
MMD2_k127_2615659_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 2.471e-317 993.0
MMD2_k127_2615659_2 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006107 329.0
MMD2_k127_2615659_3 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000057 241.0
MMD2_k127_2615659_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000283 234.0
MMD2_k127_2615659_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000007364 242.0
MMD2_k127_2615659_6 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000001205 198.0
MMD2_k127_2615659_7 LUD domain - - - 0.000000000000000000000000000000000000000000004535 171.0
MMD2_k127_2615659_8 - - - - 0.00000000000000000008133 98.0
MMD2_k127_2615659_9 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000000000003725 100.0
MMD2_k127_2722698_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 383.0
MMD2_k127_2722698_1 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000006402 185.0
MMD2_k127_2722698_2 cellulase activity - - - 0.000000000000000000000000000000001116 150.0
MMD2_k127_2722698_3 PFAM PKD domain containing protein - - - 0.000000000003429 80.0
MMD2_k127_2770042_0 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 314.0
MMD2_k127_2770042_1 Molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000000000000000000000006955 214.0
MMD2_k127_2770042_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000298 169.0
MMD2_k127_2770042_3 PFAM FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000005084 134.0
MMD2_k127_2770042_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000002468 121.0
MMD2_k127_2779759_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 597.0
MMD2_k127_2779759_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 548.0
MMD2_k127_2779759_10 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000003759 220.0
MMD2_k127_2779759_11 Acyl-CoA dehydrogenase, C-terminal domain K18244 - - 0.0000000000000000000000000000000000000000000000000001985 194.0
MMD2_k127_2779759_12 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000001784 188.0
MMD2_k127_2779759_13 PFAM Histidine triad (HIT) protein K02503 - - 0.0000000000000000000000000000000002469 134.0
MMD2_k127_2779759_14 peptidase U32 - - - 0.00000000000000000000001044 102.0
MMD2_k127_2779759_15 Psort location Cytoplasmic, score - - - 0.0000000001368 67.0
MMD2_k127_2779759_16 Putative zinc-finger - - - 0.000003743 58.0
MMD2_k127_2779759_2 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 519.0
MMD2_k127_2779759_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 421.0
MMD2_k127_2779759_4 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 357.0
MMD2_k127_2779759_5 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 344.0
MMD2_k127_2779759_6 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 286.0
MMD2_k127_2779759_7 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008755 275.0
MMD2_k127_2779759_8 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000334 252.0
MMD2_k127_2779759_9 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000002833 231.0
MMD2_k127_2802240_0 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 516.0
MMD2_k127_2802240_1 PFAM small multidrug resistance protein K03297,K11741 - - 0.000000000000000000000000000001313 124.0
MMD2_k127_2802240_2 Short C-terminal domain K08982 - - 0.000000000000281 73.0
MMD2_k127_2802240_3 Flavodoxin K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000001158 55.0
MMD2_k127_2804132_0 Elongation factor SelB, winged helix K03833 - - 1.084e-195 627.0
MMD2_k127_2804132_1 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 407.0
MMD2_k127_2804132_2 DsrE/DsrF-like family K04085 - - 0.00000000000000000000000000000000000000000000000000008682 192.0
MMD2_k127_2804132_3 Armadillo/beta-catenin-like repeats - - - 0.00000000000000000000000000000000000000000000000007061 188.0
MMD2_k127_2804132_4 cysteine desulfurase family protein - - - 0.000000000000008832 74.0
MMD2_k127_2817493_0 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008131 387.0
MMD2_k127_2817493_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 366.0
MMD2_k127_2817493_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 334.0
MMD2_k127_2817493_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 305.0
MMD2_k127_2817493_4 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000002975 200.0
MMD2_k127_2817493_5 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.000000000000000000000000000000000000001524 153.0
MMD2_k127_2864548_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 7.01e-278 871.0
MMD2_k127_2864548_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 609.0
MMD2_k127_2864548_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 474.0
MMD2_k127_2864548_3 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003342 407.0
MMD2_k127_2864548_4 Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000000000000000000000000000000000000000001493 221.0
MMD2_k127_2864548_5 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000002466 150.0
MMD2_k127_2864548_6 Protein of unknown function (DUF2769) - - - 0.000000000000000000000000318 109.0
MMD2_k127_2864548_7 Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000001171 97.0
MMD2_k127_290712_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.908e-211 660.0
MMD2_k127_290712_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 297.0
MMD2_k127_290712_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000005437 238.0
MMD2_k127_290712_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000263 214.0
MMD2_k127_290712_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000001226 83.0
MMD2_k127_290712_5 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000002586 66.0
MMD2_k127_2915798_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000002426 259.0
MMD2_k127_2915798_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000004787 247.0
MMD2_k127_2915798_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000003515 203.0
MMD2_k127_2915798_3 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000001009 184.0
MMD2_k127_2915798_4 PFAM 2-hydroxyglutaryl-CoA dehydratase D-component - - - 0.000000000000000000000000000001099 132.0
MMD2_k127_2915798_5 transcriptional - GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000002132 74.0
MMD2_k127_2915798_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000001696 52.0
MMD2_k127_2938153_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.888e-273 863.0
MMD2_k127_2938153_1 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 2.178e-215 681.0
MMD2_k127_2938153_2 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004161 274.0
MMD2_k127_2938153_3 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001931 256.0
MMD2_k127_2938153_4 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006235 250.0
MMD2_k127_2942275_0 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 505.0
MMD2_k127_2942275_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007068 400.0
MMD2_k127_2942275_2 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000008063 266.0
MMD2_k127_2942275_3 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000005731 150.0
MMD2_k127_2942275_4 Ribosomal_S15 K02956 - - 0.00000000000000000000000000006466 117.0
MMD2_k127_2943613_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000147 256.0
MMD2_k127_2943613_1 PQQ-like domain - - - 0.00005244 57.0
MMD2_k127_2945313_0 PFAM iron-containing alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 442.0
MMD2_k127_2945313_1 Acyl CoA acetate 3-ketoacid CoA transferase beta subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000002981 239.0
MMD2_k127_2945313_2 Coenzyme A transferase K01028 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000002263 237.0
MMD2_k127_2945313_3 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000008248 134.0
MMD2_k127_2945313_4 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000003592 108.0
MMD2_k127_2945313_5 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000001167 92.0
MMD2_k127_2948698_0 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 335.0
MMD2_k127_2948698_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000943 267.0
MMD2_k127_2948698_2 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002725 269.0
MMD2_k127_2948698_3 ABC-type tungstate transport system, periplasmic component K05773 - - 0.0000000000000000000000000000000000000000000000000001605 190.0
MMD2_k127_2964140_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.066e-230 724.0
MMD2_k127_2964140_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 2.126e-216 689.0
MMD2_k127_2964140_10 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000004883 234.0
MMD2_k127_2964140_11 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000001026 215.0
MMD2_k127_2964140_12 - - - - 0.0000000000000000000000000000000000000000000000000000009562 198.0
MMD2_k127_2964140_13 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000007991 204.0
MMD2_k127_2964140_14 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000001998 185.0
MMD2_k127_2964140_15 Ndr family K00433,K01055 - 1.11.1.10,3.1.1.24 0.00000000000000000000000000000000000000000002498 171.0
MMD2_k127_2964140_16 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000005969 166.0
MMD2_k127_2964140_17 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000009792 164.0
MMD2_k127_2964140_18 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000008114 156.0
MMD2_k127_2964140_19 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000004646 151.0
MMD2_k127_2964140_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 541.0
MMD2_k127_2964140_20 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000002818 143.0
MMD2_k127_2964140_21 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000001088 135.0
MMD2_k127_2964140_22 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000001436 130.0
MMD2_k127_2964140_23 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000004554 114.0
MMD2_k127_2964140_24 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000004941 116.0
MMD2_k127_2964140_25 Putative regulatory protein - - - 0.0000000000000001113 85.0
MMD2_k127_2964140_26 Peptidase M10A and M12B matrixin and adamalysin - - - 0.000000000002389 78.0
MMD2_k127_2964140_27 Zinc ribbon domain - - - 0.0000000001328 64.0
MMD2_k127_2964140_28 Putative regulatory protein - - - 0.0000009986 61.0
MMD2_k127_2964140_29 NifU-like domain - - - 0.000009893 50.0
MMD2_k127_2964140_3 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 460.0
MMD2_k127_2964140_30 regulatory protein, FmdB family - - - 0.00008826 53.0
MMD2_k127_2964140_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 424.0
MMD2_k127_2964140_5 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 353.0
MMD2_k127_2964140_6 SMART PAS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 349.0
MMD2_k127_2964140_7 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 342.0
MMD2_k127_2964140_8 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002993 294.0
MMD2_k127_2964140_9 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000004348 238.0
MMD2_k127_2992415_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.388e-246 776.0
MMD2_k127_2992415_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000002835 258.0
MMD2_k127_2992415_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000004287 243.0
MMD2_k127_2992415_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000002928 248.0
MMD2_k127_2992415_4 Reverse transcriptase-like K03469,K06864 - 3.1.26.4 0.00000000000000000000000000000000475 132.0
MMD2_k127_2992415_6 Zn-ribbon protein, possibly nucleic acid-binding K07164 - - 0.00000358 57.0
MMD2_k127_2994583_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 9.04e-289 894.0
MMD2_k127_2994583_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 583.0
MMD2_k127_2994583_10 Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.00000000000000009952 87.0
MMD2_k127_2994583_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007571 324.0
MMD2_k127_2994583_3 PFAM short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 292.0
MMD2_k127_2994583_4 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000003628 244.0
MMD2_k127_2994583_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000001783 183.0
MMD2_k127_2994583_6 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000004353 180.0
MMD2_k127_2994583_7 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000008804 118.0
MMD2_k127_2994583_8 lactoylglutathione lyase activity K05606 - 5.1.99.1 0.0000000000000000000000006995 109.0
MMD2_k127_2994583_9 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000001912 95.0
MMD2_k127_3088222_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 4.338e-198 633.0
MMD2_k127_3088222_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 619.0
MMD2_k127_3088222_2 Thiolase, C-terminal domain K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 507.0
MMD2_k127_3088222_3 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
MMD2_k127_3143088_0 glycine hydroxymethyltransferase activity K00600 GO:0001505,GO:0003674,GO:0003824,GO:0004372,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006546,GO:0006563,GO:0006565,GO:0006730,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009070,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0017144,GO:0019264,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042133,GO:0042135,GO:0042136,GO:0042737,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0065007,GO:0065008,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 529.0
MMD2_k127_3143088_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 476.0
MMD2_k127_3143088_10 - - - - 0.000000000000000000000001267 108.0
MMD2_k127_3143088_11 - - - - 0.00000000000000000003323 93.0
MMD2_k127_3143088_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000005051 93.0
MMD2_k127_3143088_13 - - - - 0.0009594 44.0
MMD2_k127_3143088_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003891 451.0
MMD2_k127_3143088_3 GTP cyclohydrolase I activity K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002553 268.0
MMD2_k127_3143088_4 competence protein - - - 0.0000000000000000000000000000000000000000000000000000000000004713 218.0
MMD2_k127_3143088_5 Diacylglycerol kinase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000005481 215.0
MMD2_k127_3143088_6 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000000001845 179.0
MMD2_k127_3143088_7 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000003184 171.0
MMD2_k127_3143088_8 - - - - 0.000000000000000000000000000004125 120.0
MMD2_k127_3143088_9 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000003417 107.0
MMD2_k127_3149554_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005766 561.0
MMD2_k127_3149554_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 497.0
MMD2_k127_3149554_2 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 410.0
MMD2_k127_3149554_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000168 223.0
MMD2_k127_3149554_4 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000003527 177.0
MMD2_k127_3153593_0 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 267.0
MMD2_k127_3153593_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000006442 246.0
MMD2_k127_3153593_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000677 129.0
MMD2_k127_3153593_3 PFAM Glutaredoxin - - - 0.00000000000000000000000000000197 123.0
MMD2_k127_3153593_4 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000000000000000006991 111.0
MMD2_k127_3153593_5 PFAM Nitroreductase family - - - 0.000000000000000000000004797 105.0
MMD2_k127_3153593_6 Cysteine-rich domain - - - 0.0000000000000000004447 97.0
MMD2_k127_3153593_7 - - - - 0.000000000000000004738 91.0
MMD2_k127_3153593_8 Rieske [2Fe-2S] domain - - - 0.000000004797 58.0
MMD2_k127_3154027_0 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 551.0
MMD2_k127_3154027_1 Biogenesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004419 281.0
MMD2_k127_3154027_2 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000002274 232.0
MMD2_k127_3154027_3 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000004234 223.0
MMD2_k127_3154027_4 Ferric uptake regulator family K03711 - - 0.000000000000000000000000000000000000001921 152.0
MMD2_k127_3154027_5 - - - - 0.000000008316 59.0
MMD2_k127_3154027_6 Predicted RNA-binding protein - - - 0.00001261 49.0
MMD2_k127_3157665_0 overlaps another CDS with the same product name - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007549 254.0
MMD2_k127_3157665_1 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002209 255.0
MMD2_k127_3157665_2 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000009922 232.0
MMD2_k127_3157665_3 PadR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000207 207.0
MMD2_k127_3157665_4 Cadherin-like beta sandwich domain - - - 0.0000007855 53.0
MMD2_k127_3189089_0 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000001055 250.0
MMD2_k127_3189089_1 AhpC/TSA family - - - 0.0000000000000000000000000000002671 134.0
MMD2_k127_3189089_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000002491 55.0
MMD2_k127_3191033_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002924 268.0
MMD2_k127_3191033_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000004909 239.0
MMD2_k127_3191033_2 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000009539 226.0
MMD2_k127_3191033_3 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000001614 213.0
MMD2_k127_3191033_4 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000105 205.0
MMD2_k127_3191033_5 CoA binding domain K06929 - - 0.00000000000000000000000000000000005499 136.0
MMD2_k127_3191033_6 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000003655 108.0
MMD2_k127_3191033_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000008987 62.0
MMD2_k127_3200044_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 396.0
MMD2_k127_3200044_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005596 269.0
MMD2_k127_3200044_2 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000004402 224.0
MMD2_k127_3200044_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000005982 169.0
MMD2_k127_3200044_4 Pyridoxamine 5'-phosphate oxidase like - - - 0.0000000000000000002179 93.0
MMD2_k127_3200044_5 Psort location CytoplasmicMembrane, score - - - 0.000000000001635 73.0
MMD2_k127_3200044_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0001815 45.0
MMD2_k127_3200697_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 341.0
MMD2_k127_3200697_1 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 342.0
MMD2_k127_3200697_2 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000001205 199.0
MMD2_k127_3200697_3 Cupin 2, conserved barrel domain protein - - - 0.000000001923 65.0
MMD2_k127_3208219_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000053 421.0
MMD2_k127_3208219_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000001798 247.0
MMD2_k127_3208219_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.00000000000000000000000000000000009467 141.0
MMD2_k127_3208219_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000006151 130.0
MMD2_k127_3208219_4 phosphoglycerate mutase K15634,K22306 - 3.1.3.85,5.4.2.12 0.00000000000000000000000005519 115.0
MMD2_k127_3208219_5 Putative peptidoglycan binding domain - GO:0000229,GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009295,GO:0009314,GO:0009408,GO:0009416,GO:0009507,GO:0009508,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0009657,GO:0009658,GO:0009889,GO:0009941,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016020,GO:0016043,GO:0016070,GO:0016853,GO:0016860,GO:0016864,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0032774,GO:0034357,GO:0034641,GO:0034645,GO:0034654,GO:0042644,GO:0042646,GO:0042651,GO:0042793,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0055035,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0097659,GO:0140096,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0003809 48.0
MMD2_k127_3210018_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006379 370.0
MMD2_k127_3210018_1 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001356 287.0
MMD2_k127_3210018_2 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000001826 270.0
MMD2_k127_3210018_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000001459 237.0
MMD2_k127_3210018_5 Initiation factor 2 subunit family K03680 - - 0.000000000000000000000001561 116.0
MMD2_k127_3210018_7 MacB-like periplasmic core domain K02004 - - 0.0000004342 53.0
MMD2_k127_3223982_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 393.0
MMD2_k127_3223982_1 Cation transport protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 404.0
MMD2_k127_3223982_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003665 341.0
MMD2_k127_3223982_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000003533 213.0
MMD2_k127_3223982_4 PFAM TrkA-N domain protein K03499 - - 0.0000000000000000000000000000000000000000000000000000000001807 213.0
MMD2_k127_3223982_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.00000000000000000000000000000000000000000000000003823 182.0
MMD2_k127_3223982_6 - - - - 0.000000000000000000000000000000000000006366 150.0
MMD2_k127_3223982_7 Epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000002437 154.0
MMD2_k127_3223982_8 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000000000000001515 131.0
MMD2_k127_3226337_0 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008965 414.0
MMD2_k127_3226337_1 TIM-barrel fold metal-dependent hydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 361.0
MMD2_k127_3226337_2 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000001043 203.0
MMD2_k127_3226337_3 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656 - 2.3.1.54 0.0000000000000004524 78.0
MMD2_k127_3226337_4 enoyl-CoA hydratase - - - 0.000185 46.0
MMD2_k127_3236450_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 447.0
MMD2_k127_3236450_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000004503 251.0
MMD2_k127_3236450_2 TM2 domain - - - 0.00000000000001521 78.0
MMD2_k127_3242755_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 571.0
MMD2_k127_3242755_1 FAD dependent oxidoreductase K05898 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 359.0
MMD2_k127_3242755_10 transcriptional - - - 0.00000000000000000001056 104.0
MMD2_k127_3242755_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 343.0
MMD2_k127_3242755_3 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001683 284.0
MMD2_k127_3242755_4 PFAM Short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000001232 214.0
MMD2_k127_3242755_5 Transcriptional regulator, Crp Fnr family K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000005208 203.0
MMD2_k127_3242755_6 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000001425 187.0
MMD2_k127_3242755_7 SnoaL-like domain - - - 0.00000000000000000000000000000000000000004348 158.0
MMD2_k127_3242755_8 SnoaL-like domain - - - 0.00000000000000000000000000000000000003889 149.0
MMD2_k127_3242755_9 helix_turn_helix ASNC type - - - 0.000000000000000000000008789 113.0
MMD2_k127_3281045_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 619.0
MMD2_k127_3281045_1 NADH oxidase K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 400.0
MMD2_k127_3281045_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000001367 97.0
MMD2_k127_3281045_3 PFAM regulatory protein AsnC Lrp family K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000611 76.0
MMD2_k127_3293064_0 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007427 503.0
MMD2_k127_3293064_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000001395 124.0
MMD2_k127_3293064_3 PFAM regulatory protein TetR - - - 0.000000000000001441 84.0
MMD2_k127_3306296_0 FAD dependent oxidoreductase K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 471.0
MMD2_k127_3306296_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001594 250.0
MMD2_k127_3306296_2 - - - - 0.00000000000000000000000000000000000000000000000000006236 191.0
MMD2_k127_3306296_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000001613 186.0
MMD2_k127_3306296_4 acid phosphatase activity - - - 0.0000000000000000000000000000001429 142.0
MMD2_k127_3311609_0 Belongs to the glycosyl hydrolase 57 family K01176,K07405 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 570.0
MMD2_k127_3311609_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 553.0
MMD2_k127_3311609_2 transferase activity, transferring glycosyl groups K02844 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008194,GO:0008610,GO:0008653,GO:0008919,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0046401,GO:0046527,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 496.0
MMD2_k127_3311609_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 351.0
MMD2_k127_3311609_4 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.0000000000000000000000000000000000000004806 163.0
MMD2_k127_3329346_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009761 376.0
MMD2_k127_3329346_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003003 251.0
MMD2_k127_3329346_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000001564 228.0
MMD2_k127_3329346_3 ferredoxin iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000006525 179.0
MMD2_k127_3329346_4 Memo-like protein K06990 - - 0.0000000009741 60.0
MMD2_k127_3331118_0 Single Cache domain 2 K02660,K03406,K05875,K05876,K07216,K11525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006461 274.0
MMD2_k127_3331118_1 histidine kinase HAMP region domain protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006751 262.0
MMD2_k127_3331118_2 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000146 152.0
MMD2_k127_3331118_3 Two component signalling adaptor domain K03408 - - 0.0003987 44.0
MMD2_k127_3336113_0 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000282 249.0
MMD2_k127_3336113_1 ubiquitin K02927,K20276 - - 0.00000000000000000000000000000000000000000000000000003701 213.0
MMD2_k127_3336113_10 - - - - 0.0000000000000003621 87.0
MMD2_k127_3336113_11 metallopeptidase activity - - - 0.000000000004214 79.0
MMD2_k127_3336113_2 - - - - 0.00000000000000000000000000000000000000000000000001554 201.0
MMD2_k127_3336113_3 Protein of unknown function (DUF1616) - - - 0.00000000000000000000000000000000000000000000002782 186.0
MMD2_k127_3336113_4 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000009174 183.0
MMD2_k127_3336113_5 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000001121 174.0
MMD2_k127_3336113_6 Putative Ig domain - - - 0.0000000000000000000000000000000000000003173 162.0
MMD2_k127_3336113_7 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000003279 163.0
MMD2_k127_3336113_8 PFAM periplasmic copper-binding - - - 0.0000000000000000000007676 111.0
MMD2_k127_3336113_9 transferase activity, transferring acyl groups - - - 0.00000000000000000006439 103.0
MMD2_k127_3346999_0 Immune inhibitor A peptidase M6 K09607 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009476 411.0
MMD2_k127_3346999_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009701 254.0
MMD2_k127_3346999_2 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000004596 142.0
MMD2_k127_3346999_3 PBS lyase K22221 - - 0.00000000000000000000000000001106 132.0
MMD2_k127_3346999_5 Belongs to the 'phage' integrase family - - - 0.00000000000000003243 87.0
MMD2_k127_3346999_6 - - - - 0.0000000000004354 81.0
MMD2_k127_3346999_7 recombinase activity - - - 0.00002042 46.0
MMD2_k127_3346999_8 Recombinase zinc beta ribbon domain - - - 0.00002073 48.0
MMD2_k127_3370254_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 6.855e-272 860.0
MMD2_k127_3370254_1 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.115e-266 852.0
MMD2_k127_3370254_10 Formate dehydrogenase iron-sulfur subunit K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000003863 243.0
MMD2_k127_3370254_11 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000000006633 235.0
MMD2_k127_3370254_12 PFAM molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000005069 201.0
MMD2_k127_3370254_13 PFAM ATP-binding region ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000008057 210.0
MMD2_k127_3370254_14 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000164 194.0
MMD2_k127_3370254_15 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000005456 171.0
MMD2_k127_3370254_16 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000005809 152.0
MMD2_k127_3370254_17 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000001466 151.0
MMD2_k127_3370254_18 Cytochrome b/b6/petB K00127 - - 0.00000000000000000000000000000000001688 144.0
MMD2_k127_3370254_19 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000002934 137.0
MMD2_k127_3370254_2 Pyridine nucleotide-disulphide oxidoreductase - - - 2.681e-215 683.0
MMD2_k127_3370254_20 Diguanylate cyclase - - - 0.0000000000000000000004521 100.0
MMD2_k127_3370254_21 Transcriptional regulatory protein, C terminal K02483,K07667 - - 0.000000000000005022 80.0
MMD2_k127_3370254_3 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.068e-200 638.0
MMD2_k127_3370254_4 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005137 578.0
MMD2_k127_3370254_5 Coenzyme F420-reducing hydrogenase, gamma subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 367.0
MMD2_k127_3370254_6 Histidine kinase K07777 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 372.0
MMD2_k127_3370254_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 321.0
MMD2_k127_3370254_8 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 297.0
MMD2_k127_3370254_9 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001232 261.0
MMD2_k127_3377451_0 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004698 268.0
MMD2_k127_3377451_1 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000003159 233.0
MMD2_k127_3377451_3 Leucine-rich repeat (LRR) protein - - - 0.000000000000000000001703 109.0
MMD2_k127_3377451_4 pentaerythritol trinitrate reductase activity K10797 - 1.3.1.31 0.000000000000001225 82.0
MMD2_k127_3377451_5 Nucleoside 2-deoxyribosyltransferase - - - 0.00000002527 58.0
MMD2_k127_3377451_6 ig-like, plexins, transcription factors - - - 0.00000008854 66.0
MMD2_k127_3377451_7 Non-ribosomal peptide synthetase modules and related proteins - - - 0.000001784 61.0
MMD2_k127_3377451_8 Carboxylesterase family K03929 - - 0.0005006 48.0
MMD2_k127_3389899_0 NAD(P)-binding Rossmann-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 396.0
MMD2_k127_3389899_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 320.0
MMD2_k127_3389899_2 Alcohol dehydrogenase GroES-like domain K00008,K00094 - 1.1.1.14,1.1.1.251 0.0000000000000000000000000000000000000006833 158.0
MMD2_k127_3389899_3 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000324 140.0
MMD2_k127_3442964_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0 1200.0
MMD2_k127_3442964_1 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006092 321.0
MMD2_k127_3442964_2 PFAM Flavin reductase like domain - - - 0.00000000000000001948 85.0
MMD2_k127_3442964_3 - - - - 0.000000002779 62.0
MMD2_k127_3442964_4 - - - - 0.000004726 55.0
MMD2_k127_3445729_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 535.0
MMD2_k127_3445729_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 GO:0003674,GO:0003824,GO:0005215,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015114,GO:0015318,GO:0015399,GO:0015405,GO:0015415,GO:0015698,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0034220,GO:0035435,GO:0042623,GO:0042626,GO:0043225,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0098656,GO:0098660,GO:0098661,GO:0099133 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 391.0
MMD2_k127_3445729_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 314.0
MMD2_k127_3445729_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000009792 128.0
MMD2_k127_3445729_4 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000766 116.0
MMD2_k127_3461903_0 Bacterial dnaA protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 456.0
MMD2_k127_3461903_1 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 418.0
MMD2_k127_3461903_2 Replicative DNA helicase K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 381.0
MMD2_k127_3461903_3 Replication initiation and membrane attachment - - - 0.000000000000000000000000000000000000000000000294 176.0
MMD2_k127_3461903_4 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000007753 138.0
MMD2_k127_3461903_5 Belongs to the peptidase S26 family - - - 0.000000000000000000000000000005803 123.0
MMD2_k127_3461903_6 amine dehydrogenase activity - - - 0.0000121 57.0
MMD2_k127_3461903_7 fumarylacetoacetate hydrolase K01557 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006570,GO:0006572,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009987,GO:0016054,GO:0016787,GO:0016822,GO:0016823,GO:0019439,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0047621,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.7.1.5 0.0000421 53.0
MMD2_k127_3467540_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 8.738e-221 696.0
MMD2_k127_3467540_1 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000003084 191.0
MMD2_k127_3467540_2 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000001621 169.0
MMD2_k127_3467540_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000000000000000000133 166.0
MMD2_k127_3467540_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000001201 57.0
MMD2_k127_3504012_0 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005021 434.0
MMD2_k127_3504012_1 Family membership - - - 0.000000000000000000006931 102.0
MMD2_k127_3553779_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 430.0
MMD2_k127_3553779_1 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 321.0
MMD2_k127_3553779_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000002232 241.0
MMD2_k127_3553779_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000002847 199.0
MMD2_k127_3553779_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000002792 193.0
MMD2_k127_3553779_5 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000009261 171.0
MMD2_k127_3553779_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000004067 123.0
MMD2_k127_3553779_7 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000000472 69.0
MMD2_k127_3568281_0 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000681 262.0
MMD2_k127_3568281_1 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000008491 245.0
MMD2_k127_3568281_2 Leucine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000001691 208.0
MMD2_k127_3572415_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 4.61e-196 631.0
MMD2_k127_3572415_1 - - - - 0.00000000000000000000000000000000000000000000000000000001967 205.0
MMD2_k127_3572415_2 - - - - 0.0000000000000000000000000000005171 136.0
MMD2_k127_3665159_0 Dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000484 332.0
MMD2_k127_3665159_1 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 295.0
MMD2_k127_3665159_2 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000727 188.0
MMD2_k127_3665159_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000004313 166.0
MMD2_k127_3665159_4 D-alanine [D-alanyl carrier protein] ligase activity - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000003518 82.0
MMD2_k127_3695218_0 Pyruvate:ferredoxin oxidoreductase core domain II K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006234 429.0
MMD2_k127_3695218_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007009 375.0
MMD2_k127_3695218_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 380.0
MMD2_k127_3695218_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 340.0
MMD2_k127_3695218_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 292.0
MMD2_k127_3695218_5 Transport permease protein K01992,K18233 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002168 284.0
MMD2_k127_3695218_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000001385 201.0
MMD2_k127_3695218_7 4Fe-4S binding domain K00176 - 1.2.7.3 0.000000000000000000000328 97.0
MMD2_k127_3719230_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 297.0
MMD2_k127_3719230_1 Glycosyl transferase family 2 K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004875 248.0
MMD2_k127_3719230_2 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000001006 246.0
MMD2_k127_3719230_3 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000001027 189.0
MMD2_k127_3719230_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000005991 140.0
MMD2_k127_3719230_5 Methyltransferase domain - - - 0.0000000000000006288 89.0
MMD2_k127_3719230_6 Glycosyltransferase like family 2 K00786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0006163 49.0
MMD2_k127_3762165_0 two-component system, chemotaxis family, sensor kinase CheA with response regulator domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 477.0
MMD2_k127_3762165_1 chemotaxis protein K03410 GO:0006935,GO:0008150,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0050896,GO:0050918 - 0.00000000000000000000000000000005755 132.0
MMD2_k127_3762165_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.0000000000000000000000000002846 122.0
MMD2_k127_3762165_3 cheY-homologous receiver domain K03413 - - 0.0000000533 54.0
MMD2_k127_3762165_4 Two component signalling adaptor domain K03408 - - 0.0007563 44.0
MMD2_k127_3791316_0 Uncharacterised conserved protein (DUF2156) K04567,K14205 - 2.3.2.3,6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009552 323.0
MMD2_k127_3791316_1 peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001459 240.0
MMD2_k127_3791316_2 glyoxalase III activity K01259 - 3.4.11.5 0.00000000000000000000000003488 112.0
MMD2_k127_3791316_3 - - - - 0.0000000002417 68.0
MMD2_k127_3979395_0 B12 binding domain - - - 1.466e-202 642.0
MMD2_k127_3979395_1 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000875 242.0
MMD2_k127_3979395_2 Domain of unknown function (DUF296) - - - 0.000000000000000000000000000000000000000000000000000000000001748 211.0
MMD2_k127_3979395_3 xylulokinase activity K00879,K11216 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006004,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008737,GO:0009056,GO:0009987,GO:0016052,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019317,GO:0019318,GO:0019320,GO:0019321,GO:0019323,GO:0019566,GO:0019568,GO:0019571,GO:0042354,GO:0042355,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046365,GO:0046372,GO:0046835,GO:0071704,GO:1901575 2.7.1.189,2.7.1.51 0.00000000000000000000000000000000000000002915 162.0
MMD2_k127_3981355_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 373.0
MMD2_k127_3981355_1 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 316.0
MMD2_k127_3992072_0 Acetolactate synthase, large subunit K01652 - 2.2.1.6 4.782e-221 699.0
MMD2_k127_3992072_1 PFAM Alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 448.0
MMD2_k127_3992072_2 metal-dependent phosphohydrolase HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009968 404.0
MMD2_k127_3992072_3 DNA modification repair radical SAM protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007798 356.0
MMD2_k127_3992072_4 - - - - 0.0000000000000003649 86.0
MMD2_k127_4008410_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 383.0
MMD2_k127_4008410_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00192,K00193 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000003296 255.0
MMD2_k127_4033244_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 296.0
MMD2_k127_4033244_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000003281 183.0
MMD2_k127_4033244_2 structural constituent of ribosome K02879 - - 0.0000000000000000000000000000000000009578 141.0
MMD2_k127_4033244_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000009582 111.0
MMD2_k127_4055540_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.098e-239 765.0
MMD2_k127_4055540_1 VWA containing CoxE family protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 432.0
MMD2_k127_4055540_2 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 391.0
MMD2_k127_4055540_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 307.0
MMD2_k127_4055540_4 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000002684 163.0
MMD2_k127_4055540_5 SNARE associated Golgi protein - - - 0.0000000000000008461 85.0
MMD2_k127_4062046_0 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003449 247.0
MMD2_k127_4062046_1 MaoC like domain - - - 0.000000000000000000000000000000005882 132.0
MMD2_k127_4062046_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000002958 74.0
MMD2_k127_4062046_3 N-terminal half of MaoC dehydratase - - - 0.000000003085 63.0
MMD2_k127_4067420_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 613.0
MMD2_k127_4067420_1 amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 535.0
MMD2_k127_4067420_10 TIGRFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007281 250.0
MMD2_k127_4067420_11 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000259 214.0
MMD2_k127_4067420_12 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000004675 194.0
MMD2_k127_4067420_13 Flavodoxin - - - 0.00000000000000000000000000000000000000003944 156.0
MMD2_k127_4067420_14 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000009139 142.0
MMD2_k127_4067420_15 Short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000175 144.0
MMD2_k127_4067420_16 Nuclear transport factor 2 (NTF2) domain K01822 - 5.3.3.1 0.000000000000000000000000000000002615 135.0
MMD2_k127_4067420_17 Thioesterase superfamily - - - 0.00000000000000000000000000005412 122.0
MMD2_k127_4067420_18 toxin-antitoxin pair type II binding - - - 0.00000000000000000000000002716 110.0
MMD2_k127_4067420_19 HIT domain K02503 - - 0.0000000001763 67.0
MMD2_k127_4067420_2 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 530.0
MMD2_k127_4067420_20 - - - - 0.0000000007721 68.0
MMD2_k127_4067420_21 Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family - - - 0.0000004235 60.0
MMD2_k127_4067420_22 Flavodoxin - - - 0.000144 50.0
MMD2_k127_4067420_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 460.0
MMD2_k127_4067420_4 alpha/beta hydrolase fold K01066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 390.0
MMD2_k127_4067420_5 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 347.0
MMD2_k127_4067420_6 Male sterility protein K00091,K19997 - 1.1.1.219,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 324.0
MMD2_k127_4067420_7 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 312.0
MMD2_k127_4067420_8 PFAM Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007973 272.0
MMD2_k127_4067420_9 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000001061 271.0
MMD2_k127_4085012_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000008046 215.0
MMD2_k127_4085012_1 - - - - 0.00000000000000000000000000000000000000000007646 176.0
MMD2_k127_4085012_2 PFAM Nitroreductase - - - 0.000000000000000000000000000000008746 130.0
MMD2_k127_4085012_3 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000272 106.0
MMD2_k127_4116050_0 PFAM Radical SAM domain protein K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 413.0
MMD2_k127_4116050_1 ATPase BadF BadG BcrA BcrD type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 389.0
MMD2_k127_4116050_2 Mechanosensitive ion channel K22044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 307.0
MMD2_k127_4116050_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000212 222.0
MMD2_k127_4116050_4 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000000000000001727 183.0
MMD2_k127_4116050_5 Chemotaxis sensory transducer K03406 - - 0.0000000000000000000000000000000000008636 152.0
MMD2_k127_412431_0 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 334.0
MMD2_k127_412431_1 SCO1/SenC - - - 0.000000000000000000000000000000000000000000000000000000000000004397 220.0
MMD2_k127_412431_2 Hemerythrin HHE cation binding K07322 - - 0.00000000000000000000000000000000000000000000000008556 181.0
MMD2_k127_412431_3 PFAM Rubrerythrin - - - 0.00000000000000000000000000003715 119.0
MMD2_k127_412431_4 4Fe-4S single cluster domain of Ferredoxin I - - - 0.00000000009717 64.0
MMD2_k127_4180186_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.827e-197 625.0
MMD2_k127_4180186_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 2.479e-197 627.0
MMD2_k127_4180186_10 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000001119 215.0
MMD2_k127_4180186_11 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000392 160.0
MMD2_k127_4180186_12 COG1960 Acyl-CoA dehydrogenases - - - 0.000000006336 59.0
MMD2_k127_4180186_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 610.0
MMD2_k127_4180186_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 546.0
MMD2_k127_4180186_4 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
MMD2_k127_4180186_5 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004271 386.0
MMD2_k127_4180186_6 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 315.0
MMD2_k127_4180186_7 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000001389 242.0
MMD2_k127_4180186_8 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000002775 220.0
MMD2_k127_4180186_9 HIT domain K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000002783 215.0
MMD2_k127_4180682_0 Two component transcriptional regulator, winged helix family K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 304.0
MMD2_k127_4180682_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004606 266.0
MMD2_k127_4180682_2 Transglutaminase-like - - - 0.00000000000000000000000000000000000000000000005707 178.0
MMD2_k127_4180682_3 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000002746 142.0
MMD2_k127_4180682_4 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000007332 127.0
MMD2_k127_4180682_5 Acid phosphatase homologues - - - 0.0000000000000000000000002253 116.0
MMD2_k127_4200721_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 421.0
MMD2_k127_4200721_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004914 370.0
MMD2_k127_4200721_2 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 318.0
MMD2_k127_4200721_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000005292 179.0
MMD2_k127_4200721_4 dUTPase K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006163,GO:0006195,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035862,GO:0035863,GO:0035870,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000001503 134.0
MMD2_k127_4200721_5 NlpC/P60 family - - - 0.0000000000942 70.0
MMD2_k127_4200721_6 Mo-molybdopterin cofactor metabolic process K00366,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0019344,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.7.7.1,2.7.7.80,2.8.1.11 0.000393 48.0
MMD2_k127_4203228_0 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.261e-213 675.0
MMD2_k127_4203228_1 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000002719 246.0
MMD2_k127_4203228_2 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.0000000000000000000000000000000000000000000000000000000004187 209.0
MMD2_k127_4203228_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000001785 160.0
MMD2_k127_4203228_4 Anthranilate synthase component I, N terminal region K01665 - 2.6.1.85 0.0000000000000000000000000000000000000004457 155.0
MMD2_k127_4203228_5 Anthranilate synthase component I K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.00000000000000000001912 93.0
MMD2_k127_4203228_6 Rieske [2Fe-2S] domain K15762 - - 0.0000000000000002027 86.0
MMD2_k127_4203228_7 DUF167 K09131 - - 0.00000000000002307 75.0
MMD2_k127_4203228_8 - - - - 0.0000000000000326 74.0
MMD2_k127_4203228_9 serine-type aminopeptidase activity - - - 0.0000000000005198 76.0
MMD2_k127_4250379_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 593.0
MMD2_k127_4250379_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 418.0
MMD2_k127_4250379_10 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.00000000000000000000000000000000000000000005641 177.0
MMD2_k127_4250379_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 411.0
MMD2_k127_4250379_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 328.0
MMD2_k127_4250379_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 319.0
MMD2_k127_4250379_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 295.0
MMD2_k127_4250379_6 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000004677 242.0
MMD2_k127_4250379_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000005641 213.0
MMD2_k127_4250379_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000003529 207.0
MMD2_k127_4250379_9 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000001049 193.0
MMD2_k127_4293603_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 3.214e-240 758.0
MMD2_k127_4293603_1 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 444.0
MMD2_k127_4293603_2 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.000000000000000000000000000000000000000000000000000000000003927 218.0
MMD2_k127_4293603_3 Telomere recombination K04656 - - 0.000000000000000000000000000000000000000000008111 166.0
MMD2_k127_4293603_4 - - - - 0.0002794 47.0
MMD2_k127_4293778_0 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 314.0
MMD2_k127_4293778_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001652 269.0
MMD2_k127_4293778_2 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000000000000000001111 199.0
MMD2_k127_4293778_3 Putative regulatory protein - - - 0.0000000000000000006587 90.0
MMD2_k127_4293778_4 Putative regulatory protein - - - 0.000000001401 63.0
MMD2_k127_4293778_5 - - - - 0.00000005035 65.0
MMD2_k127_4301290_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 3.569e-208 659.0
MMD2_k127_4301290_1 alpha/beta hydrolase fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 319.0
MMD2_k127_4301290_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000001965 202.0
MMD2_k127_4301290_3 Methyltransferase type 11 K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000001212 183.0
MMD2_k127_4301290_4 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000008111 166.0
MMD2_k127_4301290_5 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000000000004573 115.0
MMD2_k127_4301290_6 methyltransferase - - - 0.0000000000004216 79.0
MMD2_k127_4301290_7 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000001163 71.0
MMD2_k127_4301290_8 SMART Fibronectin type III domain protein - - - 0.00000005773 62.0
MMD2_k127_4301290_9 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0001063 47.0
MMD2_k127_4306622_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.318e-303 944.0
MMD2_k127_4306622_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000689 306.0
MMD2_k127_4306622_10 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000002447 83.0
MMD2_k127_4306622_2 CoA-transferase family III K07544 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 298.0
MMD2_k127_4306622_3 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000003357 235.0
MMD2_k127_4306622_4 Transcriptional regulatory protein, C terminal K07667 - - 0.0000000000000000000000000000000000000000000000000000000000000005792 230.0
MMD2_k127_4306622_5 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000000000000000000000000000000000000000000001122 214.0
MMD2_k127_4306622_6 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000005413 209.0
MMD2_k127_4306622_7 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000001143 132.0
MMD2_k127_4306622_8 HD domain - - - 0.00000000000000000000000000007993 135.0
MMD2_k127_4306622_9 diguanylate cyclase - - - 0.000000000000000000000000003056 128.0
MMD2_k127_4330555_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 1.055e-228 737.0
MMD2_k127_4330555_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 393.0
MMD2_k127_4330555_2 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 342.0
MMD2_k127_4330555_3 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000003958 241.0
MMD2_k127_4330555_4 Abc-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000005863 205.0
MMD2_k127_4330555_5 Abc-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000003066 190.0
MMD2_k127_4330555_6 Peptidase family M54 K06974 - - 0.0000000000000000003795 88.0
MMD2_k127_4330555_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000001691 59.0
MMD2_k127_4330555_8 Peptidase family M54 K06974 - - 0.00001949 49.0
MMD2_k127_4358283_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006278 399.0
MMD2_k127_4358283_1 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000005697 172.0
MMD2_k127_4358283_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000536 96.0
MMD2_k127_4358283_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000004307 80.0
MMD2_k127_4358337_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 346.0
MMD2_k127_4358337_1 Regulator of chromosome condensation (RCC1) repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 347.0
MMD2_k127_4358337_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000002483 218.0
MMD2_k127_4358337_3 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000001164 169.0
MMD2_k127_4377798_0 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 373.0
MMD2_k127_4377798_1 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000009979 243.0
MMD2_k127_4377798_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000006817 240.0
MMD2_k127_4377798_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000003459 191.0
MMD2_k127_4377798_4 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.000000000000000000000000000000000001226 144.0
MMD2_k127_4391531_0 FAD dependent oxidoreductase K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004589 399.0
MMD2_k127_4391531_1 Drug exporters of the RND superfamily K06994,K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 354.0
MMD2_k127_4391531_2 O-methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000004134 239.0
MMD2_k127_4391531_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000003413 188.0
MMD2_k127_4391531_4 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000001943 178.0
MMD2_k127_4391531_5 Probable zinc-ribbon domain - - - 0.0000000000000000000000000000000000000004239 151.0
MMD2_k127_4391531_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03855 - - 0.000000000000000000000000001151 115.0
MMD2_k127_4391531_7 RNA recognition motif - - - 0.000000000000000000000000001779 117.0
MMD2_k127_4438521_0 NAD(P)H dehydrogenase (quinone) activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001744 253.0
MMD2_k127_4438521_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000001422 220.0
MMD2_k127_4438521_2 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000516 202.0
MMD2_k127_4442355_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1520.0
MMD2_k127_4442355_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 4.653e-203 658.0
MMD2_k127_4442355_2 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.0000000000000000000001644 96.0
MMD2_k127_4473072_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 406.0
MMD2_k127_4473072_1 SMART ATPase, AAA type, core K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 310.0
MMD2_k127_4473072_2 PFAM glycosyl transferase family 2 K14597 - - 0.0000000000000000000000000000000000000000000000000000000000008367 224.0
MMD2_k127_4473072_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000479 185.0
MMD2_k127_4473072_4 Short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000001498 128.0
MMD2_k127_4473072_5 Bacterial transcriptional repressor C-terminal - - - 0.00000000000000000004278 98.0
MMD2_k127_4473072_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000005207 74.0
MMD2_k127_4523176_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 565.0
MMD2_k127_4523176_1 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002817 306.0
MMD2_k127_4523176_2 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000001102 246.0
MMD2_k127_4523176_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000007731 203.0
MMD2_k127_4523176_4 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.00000000000000000000000000000000000000000000001314 182.0
MMD2_k127_4523176_5 GAF domain K07778 - 2.7.13.3 0.00000000000000000000000000000000000000000008706 179.0
MMD2_k127_4523176_6 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 GO:0003674,GO:0003824,GO:0008966,GO:0016853,GO:0016866,GO:0016868 5.4.2.10 0.0000000000000000000000000002946 122.0
MMD2_k127_4523176_7 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000005772 108.0
MMD2_k127_4523176_8 - - - - 0.0006911 42.0
MMD2_k127_4528889_0 helix_turn_helix, Lux Regulon K03556 - - 6.196e-211 687.0
MMD2_k127_4528889_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 427.0
MMD2_k127_4528889_2 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 387.0
MMD2_k127_4528889_3 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 284.0
MMD2_k127_4528889_4 PFAM Silent information regulator protein Sir2 K12410 - - 0.0000000000000000000000000000000000000000000000000000001941 206.0
MMD2_k127_4528889_5 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000001241 191.0
MMD2_k127_4528889_6 FMN binding - - - 0.000000000000007401 79.0
MMD2_k127_4528889_7 transmembrane transport K01992 - - 0.0000000194 59.0
MMD2_k127_4528889_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000331 56.0
MMD2_k127_4568155_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 441.0
MMD2_k127_4568155_1 electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000003249 273.0
MMD2_k127_4568155_2 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008457 254.0
MMD2_k127_4568155_3 PFAM Chorismate mutase of the AroH class K06208 - 5.4.99.5 0.00000000000000000000000000000000000003866 147.0
MMD2_k127_4601729_0 AMP-binding enzyme K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 613.0
MMD2_k127_4601729_1 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 291.0
MMD2_k127_4601729_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000003651 224.0
MMD2_k127_4601729_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000003879 206.0
MMD2_k127_4601729_4 Receptor family ligand binding region K01999 - - 0.000000001588 70.0
MMD2_k127_4696772_0 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 292.0
MMD2_k127_4696772_1 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000002253 263.0
MMD2_k127_4696772_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000001272 234.0
MMD2_k127_4720020_0 Belongs to the alpha-IPM synthase homocitrate synthase family K02594 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007789 455.0
MMD2_k127_4720020_1 FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 368.0
MMD2_k127_4720020_10 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000002688 74.0
MMD2_k127_4720020_2 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007939 308.0
MMD2_k127_4720020_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002213 281.0
MMD2_k127_4720020_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008746 269.0
MMD2_k127_4720020_5 Alpha/beta hydrolase family K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004047 266.0
MMD2_k127_4720020_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000002437 208.0
MMD2_k127_4720020_7 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000004379 200.0
MMD2_k127_4720020_8 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000009819 153.0
MMD2_k127_4720020_9 SnoaL-like domain - - - 0.0000000000000000000001796 102.0
MMD2_k127_4722340_0 Elongator protein 3, MiaB family, Radical SAM - - - 9.244e-222 702.0
MMD2_k127_4722340_1 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 526.0
MMD2_k127_4722340_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004962 269.0
MMD2_k127_4722340_3 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000007323 162.0
MMD2_k127_4722340_4 - - - - 0.0000000000000000001041 90.0
MMD2_k127_4730534_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 8.713e-246 786.0
MMD2_k127_4730534_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000001439 242.0
MMD2_k127_4730534_10 - - - - 0.00000000004476 70.0
MMD2_k127_4730534_2 SMART Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000002804 242.0
MMD2_k127_4730534_3 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000169 195.0
MMD2_k127_4730534_4 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000008129 183.0
MMD2_k127_4730534_5 NAD-dependent protein deacetylase K11416 - 2.4.2.31 0.000000000000000000000000000000000000000000000005341 183.0
MMD2_k127_4730534_6 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000001161 171.0
MMD2_k127_4730534_8 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000001562 106.0
MMD2_k127_4730534_9 - - - - 0.000000000002895 71.0
MMD2_k127_4731643_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.085e-259 810.0
MMD2_k127_4731643_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 484.0
MMD2_k127_4731643_2 Fungal trichothecene efflux pump (TRI12) - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 409.0
MMD2_k127_4731643_3 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001902 276.0
MMD2_k127_4731643_4 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.0000000000000000000000000000002212 129.0
MMD2_k127_4731643_5 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.0000000000000000000000000004134 123.0
MMD2_k127_4731643_6 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000006601 84.0
MMD2_k127_4731855_0 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 567.0
MMD2_k127_4731855_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 518.0
MMD2_k127_4731855_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000001472 187.0
MMD2_k127_4731855_3 - K07018 - - 0.00000000000000000000000000000000000000000000000001407 186.0
MMD2_k127_4731855_4 Transglutaminase-like superfamily - - - 0.000002361 58.0
MMD2_k127_4742213_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 429.0
MMD2_k127_4742213_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009166 395.0
MMD2_k127_4742213_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 341.0
MMD2_k127_4742213_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 323.0
MMD2_k127_4742213_4 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 312.0
MMD2_k127_4742213_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000002023 145.0
MMD2_k127_4799338_0 Nitrite and sulphite reductase 4Fe-4S - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 352.0
MMD2_k127_4799338_1 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 321.0
MMD2_k127_4799338_2 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003215 264.0
MMD2_k127_4799338_3 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000009766 277.0
MMD2_k127_4799338_4 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000001727 228.0
MMD2_k127_4814781_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.387e-276 863.0
MMD2_k127_4814781_1 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 407.0
MMD2_k127_4814781_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 347.0
MMD2_k127_4814781_3 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 303.0
MMD2_k127_4814781_4 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 297.0
MMD2_k127_4814781_5 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004005 272.0
MMD2_k127_4814781_6 TIGRFAM degV family protein - - - 0.000000000000000000000000000000000000000000039 171.0
MMD2_k127_4814781_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000046 142.0
MMD2_k127_4814781_8 transcriptional regulator PadR family K10947 - - 0.0000000000000000000000000000006039 125.0
MMD2_k127_4814781_9 Belongs to the SEDS family - - - 0.0003983 51.0
MMD2_k127_4822605_0 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.000000000000000000000093 105.0
MMD2_k127_4822605_1 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000007217 98.0
MMD2_k127_4822605_2 subunit of the oligosaccharyltransferase complex K07151 GO:0003674,GO:0003824,GO:0004576,GO:0004579,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006464,GO:0006486,GO:0006487,GO:0006807,GO:0008150,GO:0008152,GO:0008250,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0012505,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0018193,GO:0018196,GO:0018279,GO:0019538,GO:0031984,GO:0032991,GO:0034645,GO:0036211,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043413,GO:0043686,GO:0043687,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0070085,GO:0071704,GO:0098796,GO:0098827,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990234 2.4.99.18 0.00000001229 68.0
MMD2_k127_4831133_0 Part of the ACDS complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha-epsilon subcomponent functions as a carbon monoxide dehydrogenase K00192 GO:0000302,GO:0003674,GO:0003824,GO:0004601,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016661,GO:0016684,GO:0042221,GO:0042493,GO:0042542,GO:0046677,GO:0050418,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1990748 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 363.0
MMD2_k127_4831133_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). The alpha- epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl- CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00192,K00193 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 297.0
MMD2_k127_4831133_10 - - - - 0.00005906 52.0
MMD2_k127_4831133_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001682 283.0
MMD2_k127_4831133_3 Short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 257.0
MMD2_k127_4831133_4 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000009701 254.0
MMD2_k127_4831133_5 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000001916 181.0
MMD2_k127_4831133_6 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000006339 164.0
MMD2_k127_4831133_7 formylmethanofuran dehydrogenase, subunit G K11260 - - 0.000000000000000000000000002647 117.0
MMD2_k127_4831133_8 SMART AAA ATPase K03404,K03405 - 6.6.1.1 0.000000000000228 84.0
MMD2_k127_4843492_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 468.0
MMD2_k127_4843492_1 Calcineurin-like phosphoesterase K03547 - - 0.0000000000000000000000000000000000000000001082 173.0
MMD2_k127_4843492_2 Parallel beta-helix repeats - - - 0.000000000000000000000004031 119.0
MMD2_k127_4843492_3 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000004491 55.0
MMD2_k127_4843492_4 RecF RecN SMC N terminal domain-containing protein - - - 0.0002313 54.0
MMD2_k127_4852403_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000008648 233.0
MMD2_k127_4852403_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000001218 214.0
MMD2_k127_4852403_2 MscS Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000128 184.0
MMD2_k127_4852403_3 TOBE domain - - - 0.00000000000000009095 84.0
MMD2_k127_4868973_0 Metal-dependent hydrolase, beta-lactamase superfamily II K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 302.0
MMD2_k127_4868973_1 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 299.0
MMD2_k127_4868973_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003367 278.0
MMD2_k127_4868973_3 Thioredoxin K03671 - - 0.0000000000000000000000000000000005195 142.0
MMD2_k127_4868973_4 4 iron, 4 sulfur cluster binding K02574 - - 0.0000000000000000000000000000001487 130.0
MMD2_k127_4868973_5 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000203 128.0
MMD2_k127_4868973_6 protein-disulfide reductase activity - - - 0.000000341 55.0
MMD2_k127_4884407_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 2.749e-224 711.0
MMD2_k127_4884407_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006223 300.0
MMD2_k127_4884407_2 TIGRFAM glycerol-3-phosphate dehydrogenase, anaerobic, C subunit K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002572 257.0
MMD2_k127_4884407_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000001154 209.0
MMD2_k127_4884407_4 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000007858 195.0
MMD2_k127_4884407_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000005932 176.0
MMD2_k127_4884407_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000009156 150.0
MMD2_k127_4884407_7 4Fe-4S binding domain - - - 0.000000000000000000000000000004134 126.0
MMD2_k127_4884407_8 6-phosphogluconate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000001383 121.0
MMD2_k127_4927995_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 484.0
MMD2_k127_4927995_1 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008774 317.0
MMD2_k127_4927995_2 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000414 284.0
MMD2_k127_4927995_3 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000000821 188.0
MMD2_k127_4927995_4 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000000000000000138 169.0
MMD2_k127_4927995_5 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000002876 111.0
MMD2_k127_4927995_6 sulfur carrier activity - - - 0.0000000000000000000002098 97.0
MMD2_k127_4927995_7 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0006046 45.0
MMD2_k127_4948610_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 346.0
MMD2_k127_4948610_1 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003058 273.0
MMD2_k127_4948610_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000003769 235.0
MMD2_k127_4948610_3 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000003185 205.0
MMD2_k127_4948610_4 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000006295 121.0
MMD2_k127_4948610_5 - - - - 0.0000002065 57.0
MMD2_k127_4948610_6 - - - - 0.0000004722 51.0
MMD2_k127_4954498_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 499.0
MMD2_k127_4954498_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004877 281.0
MMD2_k127_4954498_2 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000001946 255.0
MMD2_k127_4954498_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000004211 188.0
MMD2_k127_4954498_4 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000307 76.0
MMD2_k127_4954498_5 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000007512 76.0
MMD2_k127_4954498_6 Cupin 2, conserved barrel domain protein - - - 0.0000000008365 66.0
MMD2_k127_4954498_7 Cupin 2, conserved barrel domain protein - - - 0.00000001183 63.0
MMD2_k127_4967255_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 3.667e-295 924.0
MMD2_k127_4967255_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006605,GO:0006612,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0030312,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032991,GO:0033036,GO:0034613,GO:0035639,GO:0036094,GO:0040007,GO:0042886,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045184,GO:0046907,GO:0048500,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0072657,GO:0090150,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1990904 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 512.0
MMD2_k127_4967255_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000001103 177.0
MMD2_k127_4967255_11 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000001088 164.0
MMD2_k127_4967255_12 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000007112 97.0
MMD2_k127_4967255_14 TM2 domain - - - 0.0000000002565 67.0
MMD2_k127_4967255_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 465.0
MMD2_k127_4967255_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 466.0
MMD2_k127_4967255_4 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004705 438.0
MMD2_k127_4967255_5 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 332.0
MMD2_k127_4967255_6 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 306.0
MMD2_k127_4967255_7 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000977 250.0
MMD2_k127_4967255_8 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000001956 217.0
MMD2_k127_4967255_9 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000006166 209.0
MMD2_k127_4981206_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain - - - 3.923e-265 829.0
MMD2_k127_4981206_1 NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 436.0
MMD2_k127_4981206_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 294.0
MMD2_k127_4981206_3 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001057 270.0
MMD2_k127_4981206_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002204 265.0
MMD2_k127_4981206_5 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007409 269.0
MMD2_k127_4981206_6 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006858 261.0
MMD2_k127_4981206_7 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000319 230.0
MMD2_k127_4981206_8 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000001817 160.0
MMD2_k127_4990541_0 Two component transcriptional regulator, winged helix family K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001497 283.0
MMD2_k127_4990541_1 histidine kinase HAMP region domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006508 269.0
MMD2_k127_4990541_2 PFAM Methyltransferase - - - 0.000000000000000000245 91.0
MMD2_k127_4990541_3 YHS domain - - - 0.00000000000485 68.0
MMD2_k127_4990541_4 Short C-terminal domain K08982 - - 0.000000003374 64.0
MMD2_k127_4990541_5 Zinc metalloprotease (Elastase) - - - 0.00001219 52.0
MMD2_k127_4994108_0 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 525.0
MMD2_k127_4994108_1 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 340.0
MMD2_k127_4994108_10 cheY-homologous receiver domain - - - 0.0000001466 53.0
MMD2_k127_4994108_11 - - - - 0.000003276 55.0
MMD2_k127_4994108_2 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 318.0
MMD2_k127_4994108_3 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000023 264.0
MMD2_k127_4994108_4 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000003112 249.0
MMD2_k127_4994108_5 ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000005463 181.0
MMD2_k127_4994108_6 Acetyltransferase (GNAT) domain K03830 - - 0.00000000000000000000000000000000007857 139.0
MMD2_k127_4994108_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000105 132.0
MMD2_k127_4994108_8 secreted hydrolase - - - 0.000000000000000000000000000002997 133.0
MMD2_k127_5025012_0 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002971 391.0
MMD2_k127_5025012_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 379.0
MMD2_k127_5025012_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 361.0
MMD2_k127_5025012_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 299.0
MMD2_k127_5025012_4 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000611 224.0
MMD2_k127_5025012_5 BioY protein K03523 - - 0.000000000000000000000000000000000000000002459 164.0
MMD2_k127_5025012_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000002534 150.0
MMD2_k127_5025012_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000002251 144.0
MMD2_k127_5041543_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 383.0
MMD2_k127_5041543_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 338.0
MMD2_k127_5041543_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000001951 185.0
MMD2_k127_5041543_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000002129 148.0
MMD2_k127_5041543_4 Domain of unknown function (DUF2520) - - - 0.000000000000000000003737 94.0
MMD2_k127_5041543_5 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.000000000000002735 78.0
MMD2_k127_5050269_0 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002525 539.0
MMD2_k127_5050269_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004455 392.0
MMD2_k127_5050269_2 PFAM Prokaryotic protein of K18013 - 2.3.1.247 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 333.0
MMD2_k127_5050269_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001219 261.0
MMD2_k127_5050269_4 electron transfer activity K00335,K02572,K03616 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000009127 240.0
MMD2_k127_5050269_5 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000001593 176.0
MMD2_k127_5071242_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009451,GO:0009628,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0050896,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.485e-214 680.0
MMD2_k127_5071242_1 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 419.0
MMD2_k127_5071242_2 ig-like, plexins, transcription factors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 379.0
MMD2_k127_5071242_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000002035 222.0
MMD2_k127_5071242_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000000006704 192.0
MMD2_k127_5071242_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000004025 164.0
MMD2_k127_5071242_6 Activator of Hsp90 ATPase - - - 0.000000000000000000000001661 110.0
MMD2_k127_5071242_7 Belongs to the peptidase S26 family - - - 0.00000000000000000001826 99.0
MMD2_k127_5071242_8 MarR family - - - 0.00000000001098 72.0
MMD2_k127_5082930_0 Conserved carboxylase domain K01960 - 6.4.1.1 1.091e-236 745.0
MMD2_k127_5082930_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 529.0
MMD2_k127_5082930_2 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 492.0
MMD2_k127_5082930_3 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000004554 211.0
MMD2_k127_5082930_4 DoxX - - - 0.000000007555 67.0
MMD2_k127_5082930_5 PFAM UBA THIF-type NAD FAD binding protein K21029,K21147 - 2.7.7.80,2.8.1.11 0.0002938 48.0
MMD2_k127_5083310_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.048e-222 706.0
MMD2_k127_5083310_1 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000003891 238.0
MMD2_k127_5083310_2 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000005419 107.0
MMD2_k127_5083310_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.000000000000000000002426 94.0
MMD2_k127_5098003_0 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 565.0
MMD2_k127_5098003_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000004296 214.0
MMD2_k127_5098003_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000005648 151.0
MMD2_k127_5098003_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000001657 100.0
MMD2_k127_5098003_4 GYD domain - - - 0.0000000000000000008849 89.0
MMD2_k127_5098003_5 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000009346 68.0
MMD2_k127_5098003_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000001742 62.0
MMD2_k127_5099862_0 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000001699 170.0
MMD2_k127_5099862_1 membrane - - - 0.000000000000000000000000000000000000000007803 178.0
MMD2_k127_5099862_2 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000005827 146.0
MMD2_k127_5099862_3 - - - - 0.00002031 55.0
MMD2_k127_5131164_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 445.0
MMD2_k127_5131164_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 391.0
MMD2_k127_5131164_2 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 308.0
MMD2_k127_5131164_3 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000002373 268.0
MMD2_k127_5131164_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000001417 130.0
MMD2_k127_5131164_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000006439 107.0
MMD2_k127_5131164_6 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000005062 70.0
MMD2_k127_5168284_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 2.379e-214 675.0
MMD2_k127_5168284_2 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000133 157.0
MMD2_k127_5168284_3 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000000001412 130.0
MMD2_k127_5168284_4 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000007509 119.0
MMD2_k127_5168284_5 Esterase PHB depolymerase - - - 0.00002407 57.0
MMD2_k127_5247807_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 5.799e-211 671.0
MMD2_k127_5247807_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 435.0
MMD2_k127_5247807_10 GrpB protein - - - 0.000000000000000000000000000000000000000000000000000001946 196.0
MMD2_k127_5247807_11 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000006055 196.0
MMD2_k127_5247807_12 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000002448 122.0
MMD2_k127_5247807_13 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000005035 103.0
MMD2_k127_5247807_14 Protein of unknown function (DUF448) K07742 - - 0.000000000000000000986 91.0
MMD2_k127_5247807_15 RDD family - - - 0.00000000000000001544 90.0
MMD2_k127_5247807_16 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0001317 49.0
MMD2_k127_5247807_2 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 418.0
MMD2_k127_5247807_3 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 410.0
MMD2_k127_5247807_4 ig-like, plexins, transcription factors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 393.0
MMD2_k127_5247807_5 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003077 364.0
MMD2_k127_5247807_6 Phosphoesterase family K01114 - 3.1.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 348.0
MMD2_k127_5247807_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 303.0
MMD2_k127_5247807_8 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001379 262.0
MMD2_k127_5247807_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000201 263.0
MMD2_k127_5257453_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 6.016e-265 826.0
MMD2_k127_5257453_1 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000009151 225.0
MMD2_k127_5257453_2 Protein of unknown function (DUF2851) - - - 0.000000000000000000000000000000000000000000000000001054 201.0
MMD2_k127_5257453_3 helix-turn-helix domain protein - - - 0.0000000000000007312 79.0
MMD2_k127_5268245_0 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000001222 239.0
MMD2_k127_5268245_1 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000004634 195.0
MMD2_k127_5268245_2 PFAM B12 binding domain - - - 0.000000000000000000000000000000000000006271 155.0
MMD2_k127_5268245_3 conserved repeat domain protein - - - 0.0000000000000000000005087 113.0
MMD2_k127_5268245_4 Archaeal Type IV pilin, N-terminal - - - 0.00000000000001524 89.0
MMD2_k127_5268245_5 cell wall binding repeat 2 - - - 0.00000000007106 76.0
MMD2_k127_5297913_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 8.507e-202 644.0
MMD2_k127_5297913_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 582.0
MMD2_k127_5297913_10 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 312.0
MMD2_k127_5297913_11 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003723 294.0
MMD2_k127_5297913_12 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001206 285.0
MMD2_k127_5297913_13 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008413 274.0
MMD2_k127_5297913_14 to orf3 of fosmid clone 4B7mr3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002336 246.0
MMD2_k127_5297913_15 Methyltransferase K15256 - - 0.000000000000000000000000000000000000000000000000000000000000001633 226.0
MMD2_k127_5297913_16 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000001445 205.0
MMD2_k127_5297913_17 - - - - 0.000000000000000000000000000000000000000000000000007707 199.0
MMD2_k127_5297913_18 acetyltransferase - - - 0.000000000000000000000000000000000000000000000006377 181.0
MMD2_k127_5297913_19 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000007152 179.0
MMD2_k127_5297913_2 Arsenical pump membrane protein K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 529.0
MMD2_k127_5297913_20 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000542 168.0
MMD2_k127_5297913_21 MaoC domain protein dehydratase K00634,K17865 - 2.3.1.19,4.2.1.55 0.00000000000000000000000000000000000002451 147.0
MMD2_k127_5297913_22 Haloacid dehalogenase-like hydrolase K02101 - - 0.00000000000000000000000000000000004719 145.0
MMD2_k127_5297913_23 - - - - 0.00000000000000000000000002335 112.0
MMD2_k127_5297913_24 GtrA-like protein - - - 0.000000000000000000000005633 107.0
MMD2_k127_5297913_25 Pfam:DUF2029 - - - 0.0000000000000000002335 102.0
MMD2_k127_5297913_26 EamA-like transporter family - - - 0.000000000004832 71.0
MMD2_k127_5297913_27 cell wall anchor domain - - - 0.000000000009883 78.0
MMD2_k127_5297913_28 Bacterial membrane protein YfhO - - - 0.000000002091 71.0
MMD2_k127_5297913_3 ADP-glyceromanno-heptose 6-epimerase activity K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 504.0
MMD2_k127_5297913_30 Membrane - - - 0.0000009075 63.0
MMD2_k127_5297913_4 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 474.0
MMD2_k127_5297913_5 Dolichol monophosphate mannose synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 420.0
MMD2_k127_5297913_6 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 416.0
MMD2_k127_5297913_7 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 409.0
MMD2_k127_5297913_8 Glucose-1-phosphate cytidylyltransferase K00978 - 2.7.7.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 378.0
MMD2_k127_5297913_9 Short-chain dehydrogenase reductase SDR K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004876 381.0
MMD2_k127_5313214_0 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 300.0
MMD2_k127_5313214_1 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003817 295.0
MMD2_k127_5313214_10 - - - - 0.000001584 57.0
MMD2_k127_5313214_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009859 286.0
MMD2_k127_5313214_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000009758 267.0
MMD2_k127_5313214_4 PFAM Pterin binding enzyme K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000557 243.0
MMD2_k127_5313214_5 Flavin containing amine oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000001335 213.0
MMD2_k127_5313214_6 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000003938 177.0
MMD2_k127_5313214_7 methyltransferase activity K16176 - 2.1.1.248 0.0000000000000000000000000000000000000000002885 175.0
MMD2_k127_5313214_8 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000009997 135.0
MMD2_k127_5313214_9 Flavin containing amine oxidoreductase - - - 0.0000000001254 65.0
MMD2_k127_5316741_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 385.0
MMD2_k127_5316741_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008728 270.0
MMD2_k127_5316741_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000002494 151.0
MMD2_k127_5316741_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000001645 141.0
MMD2_k127_5316741_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000001257 121.0
MMD2_k127_5316741_13 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000002716 114.0
MMD2_k127_5316741_14 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000007601 104.0
MMD2_k127_5316741_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000000009071 101.0
MMD2_k127_5316741_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000009818 94.0
MMD2_k127_5316741_17 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000001297 84.0
MMD2_k127_5316741_18 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000001435 66.0
MMD2_k127_5316741_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001582 254.0
MMD2_k127_5316741_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000003957 211.0
MMD2_k127_5316741_4 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001163 207.0
MMD2_k127_5316741_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000001485 191.0
MMD2_k127_5316741_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000006893 184.0
MMD2_k127_5316741_7 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000002 184.0
MMD2_k127_5316741_8 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000002295 173.0
MMD2_k127_5316741_9 Binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000001008 166.0
MMD2_k127_5371502_0 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003972 484.0
MMD2_k127_5371502_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 464.0
MMD2_k127_5371502_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 299.0
MMD2_k127_5371502_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 294.0
MMD2_k127_5371502_4 Peptidase MA superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001288 258.0
MMD2_k127_5371502_5 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000006958 192.0
MMD2_k127_5371502_6 - - - - 0.0000000000000000000000000000000000000000001542 164.0
MMD2_k127_5371502_7 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000004507 134.0
MMD2_k127_5371502_8 PFAM periplasmic copper-binding - - - 0.00000000000001408 83.0
MMD2_k127_5380854_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 3.198e-224 713.0
MMD2_k127_5380854_1 Formyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 318.0
MMD2_k127_5380854_2 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 310.0
MMD2_k127_5380854_3 PHP-associated - - - 0.00000000000000000000000000000000000000000000000000000000003679 213.0
MMD2_k127_5380854_4 Catalyzes a trans-dehydration via an enolate intermediate K03786,K16021 - 4.2.1.10 0.00000000000000000000000000000000000000000000005219 178.0
MMD2_k127_5380854_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000639 75.0
MMD2_k127_5380854_6 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000001128 73.0
MMD2_k127_5412872_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 400.0
MMD2_k127_5412872_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 283.0
MMD2_k127_5412872_2 B12- binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000002039 139.0
MMD2_k127_5412872_3 - - - - 0.0000000000000000000000000000001363 126.0
MMD2_k127_5412872_4 Oxidoreductase NAD-binding domain - - - 0.000000000004133 66.0
MMD2_k127_5412872_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000005932 72.0
MMD2_k127_5429686_0 Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000303 253.0
MMD2_k127_5429686_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000004523 146.0
MMD2_k127_5429686_2 PFAM alpha beta hydrolase fold K01259 - 3.4.11.5 0.000000000000000000000000000003315 127.0
MMD2_k127_5429686_3 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000003133 120.0
MMD2_k127_5429686_4 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000584 118.0
MMD2_k127_5429686_5 Domain of unknown function (DUF4382) - - - 0.000000000000000000004419 104.0
MMD2_k127_5429686_6 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 0.0000000000000000005188 92.0
MMD2_k127_5429686_7 - - - - 0.00009064 54.0
MMD2_k127_5457840_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.614e-226 732.0
MMD2_k127_5457840_1 FAD dependent oxidoreductase K05898 - 1.3.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 521.0
MMD2_k127_5457840_2 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000001159 131.0
MMD2_k127_5457840_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000000008343 124.0
MMD2_k127_5457840_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.000000000000000000000000513 109.0
MMD2_k127_5483270_0 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 507.0
MMD2_k127_5483270_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 437.0
MMD2_k127_5483270_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 337.0
MMD2_k127_5483270_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 313.0
MMD2_k127_5483270_4 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003968 309.0
MMD2_k127_5483270_5 Zinc-binding dehydrogenase K00055,K00121 - 1.1.1.1,1.1.1.284,1.1.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009385 291.0
MMD2_k127_5483270_6 ATPase domain of DNA mismatch repair MUTS family - - - 0.000000000000000000000344 108.0
MMD2_k127_5487656_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.293e-196 621.0
MMD2_k127_5487656_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007906 274.0
MMD2_k127_5487656_2 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000003517 238.0
MMD2_k127_5487656_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000004506 225.0
MMD2_k127_5487656_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000003407 201.0
MMD2_k127_5487656_5 COGs COG0589 Universal stress protein UspA and related nucleotide-binding protein - - - 0.00000000000000000000001328 109.0
MMD2_k127_5503121_0 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008463 414.0
MMD2_k127_5503121_1 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000001955 172.0
MMD2_k127_5503121_2 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000003524 135.0
MMD2_k127_5503121_3 PFAM SpoVT AbrB domain protein K07172 - - 0.00000000000000000000001755 104.0
MMD2_k127_5503121_4 Thioesterase-like superfamily K07107,K12500 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016289,GO:0016787,GO:0016788,GO:0016790,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0047617,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.000000000000007565 85.0
MMD2_k127_5503121_5 Acyl-ACP thioesterase K07107 - - 0.0000000000002575 81.0
MMD2_k127_5503121_6 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.0000000004449 60.0
MMD2_k127_5503121_7 MarR family - - - 0.000005084 54.0
MMD2_k127_5504034_0 Pyridine nucleotide-disulphide oxidoreductase - - - 4.368e-293 928.0
MMD2_k127_5504034_1 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 415.0
MMD2_k127_5504034_2 Citrate transporter K03893 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 352.0
MMD2_k127_5504034_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 287.0
MMD2_k127_5504034_4 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000001205 74.0
MMD2_k127_5523216_0 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.0000000000000000000000000000000000000000000000000001654 197.0
MMD2_k127_5523216_1 PFAM Integrase catalytic region - - - 0.00000000000000000000000000001068 133.0
MMD2_k127_5523216_2 Peptidase S24-like K13280 - 3.4.21.89 0.0000000000000000000000001459 120.0
MMD2_k127_5523216_4 Kelch motif - - - 0.0008887 51.0
MMD2_k127_5523938_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1056.0
MMD2_k127_5523938_1 Fungal trichothecene efflux pump (TRI12) - GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.000000000000000000000000000000000000000000000000000489 192.0
MMD2_k127_5523938_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000007076 113.0
MMD2_k127_5523938_3 GlcNAc-PI de-N-acetylase K22408 - - 0.0000000000000001396 90.0
MMD2_k127_5550969_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 3.123e-199 638.0
MMD2_k127_5550969_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 590.0
MMD2_k127_5550969_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000002599 194.0
MMD2_k127_5550969_11 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000001125 188.0
MMD2_k127_5550969_12 ACT domain - - - 0.0000000000000000000000000000000000000000009191 162.0
MMD2_k127_5550969_13 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000008712 166.0
MMD2_k127_5550969_14 4Fe-4S dicluster domain - - - 0.0000000000000000000000009205 108.0
MMD2_k127_5550969_2 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 405.0
MMD2_k127_5550969_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 355.0
MMD2_k127_5550969_4 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 338.0
MMD2_k127_5550969_5 Abc transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001596 276.0
MMD2_k127_5550969_6 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001778 279.0
MMD2_k127_5550969_7 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004489 249.0
MMD2_k127_5550969_8 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002021 248.0
MMD2_k127_5550969_9 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000003044 205.0
MMD2_k127_5568433_0 LVIVD repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000347 579.0
MMD2_k127_5568433_1 succinate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 365.0
MMD2_k127_5568433_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007584 262.0
MMD2_k127_5568433_3 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004395 259.0
MMD2_k127_5568433_4 succinate dehydrogenase - - - 0.0000000000000000000000000000000000001351 150.0
MMD2_k127_5568433_5 4Fe-4S dicluster domain - - - 0.0000000000002922 72.0
MMD2_k127_5584795_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007521 430.0
MMD2_k127_5584795_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000003194 72.0
MMD2_k127_5609985_0 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 565.0
MMD2_k127_5609985_1 molybdopterin cofactor binding K00183 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005795 509.0
MMD2_k127_5609985_10 - - - - 0.00000001063 66.0
MMD2_k127_5609985_2 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007915 407.0
MMD2_k127_5609985_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002936 312.0
MMD2_k127_5609985_4 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001195 270.0
MMD2_k127_5609985_5 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000001543 192.0
MMD2_k127_5609985_6 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000003203 149.0
MMD2_k127_5609985_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000004475 111.0
MMD2_k127_5609985_8 - - - - 0.00000000002781 74.0
MMD2_k127_5609985_9 Methyl-transferase - - - 0.0000000004061 71.0
MMD2_k127_5611347_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 1.135e-212 676.0
MMD2_k127_5611347_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 420.0
MMD2_k127_5611347_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000003386 203.0
MMD2_k127_5611347_11 60Kd inner membrane protein K03217 - - 0.0000000000000000000000000000000000000000000000000000006431 203.0
MMD2_k127_5611347_12 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000005672 208.0
MMD2_k127_5611347_13 KH domain K06346 - - 0.0000000000000000000000000000000000000000000000001385 184.0
MMD2_k127_5611347_14 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000004067 182.0
MMD2_k127_5611347_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000004201 178.0
MMD2_k127_5611347_16 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000006957 170.0
MMD2_k127_5611347_17 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000001986 171.0
MMD2_k127_5611347_18 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000000000001016 165.0
MMD2_k127_5611347_19 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000009339 154.0
MMD2_k127_5611347_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 357.0
MMD2_k127_5611347_20 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000001302 146.0
MMD2_k127_5611347_21 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000007162 105.0
MMD2_k127_5611347_22 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000000004952 88.0
MMD2_k127_5611347_23 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000007069 66.0
MMD2_k127_5611347_24 - - - - 0.00003329 51.0
MMD2_k127_5611347_3 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 325.0
MMD2_k127_5611347_4 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000357 297.0
MMD2_k127_5611347_5 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005535 282.0
MMD2_k127_5611347_6 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007104 284.0
MMD2_k127_5611347_7 PFAM ABC transporter related K02013 - 3.6.3.34 0.00000000000000000000000000000000000000000000000000000000000000001901 238.0
MMD2_k127_5611347_8 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.00000000000000000000000000000000000000000000000000000000000005804 222.0
MMD2_k127_5611347_9 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000001791 211.0
MMD2_k127_5620817_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0 1219.0
MMD2_k127_5620817_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 1.311e-314 985.0
MMD2_k127_5620817_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 469.0
MMD2_k127_5620817_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 355.0
MMD2_k127_5620817_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000009001 231.0
MMD2_k127_5620817_5 DUF35 OB-fold domain, acyl-CoA-associated K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000004136 177.0
MMD2_k127_5620817_6 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000004538 95.0
MMD2_k127_5640416_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006826 310.0
MMD2_k127_5640416_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005981 246.0
MMD2_k127_5640416_2 PFAM Class I peptide chain release factor K15034 - - 0.0000000000001015 76.0
MMD2_k127_5640416_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000398 62.0
MMD2_k127_5671030_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 5.664e-306 951.0
MMD2_k127_5671030_1 Histidine kinase K07646 - 2.7.13.3 2.895e-265 844.0
MMD2_k127_5671030_10 Conserved region in glutamate synthase - - - 0.00000000000000003311 83.0
MMD2_k127_5671030_2 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 4.289e-254 796.0
MMD2_k127_5671030_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 1.461e-216 679.0
MMD2_k127_5671030_4 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 557.0
MMD2_k127_5671030_5 Two component transcriptional regulator, winged helix family K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 291.0
MMD2_k127_5671030_6 GXGXG motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005023 278.0
MMD2_k127_5671030_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000000005908 239.0
MMD2_k127_5671030_8 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000003467 176.0
MMD2_k127_5671030_9 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000000001485 158.0
MMD2_k127_5702496_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 486.0
MMD2_k127_5702496_1 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 340.0
MMD2_k127_5702496_2 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005413 266.0
MMD2_k127_5702496_3 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000007892 135.0
MMD2_k127_5702496_4 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0002031 44.0
MMD2_k127_5717749_0 PFAM CoA-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000007477 240.0
MMD2_k127_5717749_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000002087 224.0
MMD2_k127_5717749_2 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000001089 76.0
MMD2_k127_5720430_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 494.0
MMD2_k127_5720430_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 319.0
MMD2_k127_5720430_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 308.0
MMD2_k127_5720430_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000654 264.0
MMD2_k127_5744686_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1067.0
MMD2_k127_5744686_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 7.679e-218 687.0
MMD2_k127_5744686_2 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 347.0
MMD2_k127_5744686_3 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000844 212.0
MMD2_k127_5744686_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000002957 146.0
MMD2_k127_5744686_5 - - - - 0.0000000642 61.0
MMD2_k127_5744686_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000002099 53.0
MMD2_k127_5784439_0 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 592.0
MMD2_k127_5784439_1 TIGRFAM MIP family channel K02440,K06188 - - 0.0000000000000000000000000000000000000000000000000000000002465 207.0
MMD2_k127_5784439_2 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000003979 193.0
MMD2_k127_5784439_3 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000001087 189.0
MMD2_k127_5784439_4 Fibronectin type III domain protein K21571 - - 0.0000000000001546 86.0
MMD2_k127_5784439_5 SMART Fibronectin type III domain protein - - - 0.000000000005515 81.0
MMD2_k127_5788234_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 1.871e-227 729.0
MMD2_k127_5788234_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 439.0
MMD2_k127_5788234_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000003973 205.0
MMD2_k127_5788234_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000399 195.0
MMD2_k127_5788234_4 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000007264 184.0
MMD2_k127_5788234_5 Domain of unknown function (DUF4070) - - - 0.0000000000000000000000000000000000000000006556 162.0
MMD2_k127_5788234_6 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000126 147.0
MMD2_k127_5788234_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000002322 74.0
MMD2_k127_5788234_8 Prokaryotic N-terminal methylation motif K02650 - - 0.0004761 48.0
MMD2_k127_5800906_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 7.26e-221 697.0
MMD2_k127_5800906_1 Iron-sulfur cluster-binding protein K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 499.0
MMD2_k127_5800906_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 326.0
MMD2_k127_5800906_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004632 312.0
MMD2_k127_5800906_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 291.0
MMD2_k127_5800906_5 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000007722 246.0
MMD2_k127_5800906_6 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000001273 218.0
MMD2_k127_5800906_7 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.00000000000000000000000000000000000000000000000000001958 201.0
MMD2_k127_5800906_8 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000004369 187.0
MMD2_k127_5800906_9 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000001567 134.0
MMD2_k127_5824358_0 Tetratricopeptide repeat K12600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 355.0
MMD2_k127_5824358_1 metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 371.0
MMD2_k127_5824358_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000158 241.0
MMD2_k127_5824358_3 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000001892 249.0
MMD2_k127_5824358_4 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000006181 205.0
MMD2_k127_5824358_5 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000000258 131.0
MMD2_k127_5824358_6 Competence protein ComEC K02238 - - 0.0000000000000000001041 90.0
MMD2_k127_5827588_0 protoporphyrinogen oxidase activity K00231 - 1.3.3.15,1.3.3.4 9.511e-197 621.0
MMD2_k127_5827588_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 366.0
MMD2_k127_5827588_10 Hydrogenase/urease nickel incorporation, metallochaperone, hypA - - - 0.0000000000000000000000000002589 117.0
MMD2_k127_5827588_11 N-terminal half of MaoC dehydratase - - - 0.0000004963 58.0
MMD2_k127_5827588_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 323.0
MMD2_k127_5827588_3 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 325.0
MMD2_k127_5827588_4 PFAM L-carnitine dehydratase bile acid-inducible protein F K18702 - 2.8.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000718 275.0
MMD2_k127_5827588_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002115 258.0
MMD2_k127_5827588_6 Belongs to the thiolase family K00626 GO:0003674,GO:0003824,GO:0003988,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000006873 252.0
MMD2_k127_5827588_7 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000001007 254.0
MMD2_k127_5827588_8 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000005752 240.0
MMD2_k127_5827588_9 KR domain K00046 - 1.1.1.69 0.0000000000000000000000000000000002855 136.0
MMD2_k127_5851853_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 597.0
MMD2_k127_5851853_1 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 592.0
MMD2_k127_5851853_10 Peptidase S24-like K13280 - 3.4.21.89 0.0000000000000000000000002827 113.0
MMD2_k127_5851853_11 - - - - 0.000000000000000000000001644 113.0
MMD2_k127_5851853_12 - - - - 0.00000000000000000004658 100.0
MMD2_k127_5851853_13 Preprotein translocase SecG subunit K03075 - - 0.000000000000001256 78.0
MMD2_k127_5851853_14 - - - - 0.000003138 50.0
MMD2_k127_5851853_15 Transcriptional regulator, MarR family - - - 0.0002177 51.0
MMD2_k127_5851853_2 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 293.0
MMD2_k127_5851853_3 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 292.0
MMD2_k127_5851853_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000009084 235.0
MMD2_k127_5851853_5 Two component transcriptional regulator, winged helix family - - - 0.0000000000000000000000000000000000000000000000000000000000000001227 228.0
MMD2_k127_5851853_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000008982 213.0
MMD2_k127_5851853_7 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000005635 217.0
MMD2_k127_5851853_8 Periplasmic Protein - - - 0.0000000000000000000000000000000000000000000000009899 189.0
MMD2_k127_5851853_9 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000005578 167.0
MMD2_k127_5880296_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 573.0
MMD2_k127_5880296_1 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 315.0
MMD2_k127_5880296_2 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 308.0
MMD2_k127_5880296_3 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 291.0
MMD2_k127_5880296_4 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000004178 153.0
MMD2_k127_5880296_5 PFAM Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000002034 156.0
MMD2_k127_5880296_6 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000001192 121.0
MMD2_k127_5880296_7 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000001504 118.0
MMD2_k127_5880296_8 Binds the 23S rRNA K02909 - - 0.00000000000000000000000001873 110.0
MMD2_k127_5880296_9 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000261 96.0
MMD2_k127_5889004_0 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000221 232.0
MMD2_k127_5889004_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00263 - 1.4.1.9 0.00000000000000000000000000000009631 134.0
MMD2_k127_5889004_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000001243 91.0
MMD2_k127_5889004_3 IMP dehydrogenase activity K03406,K15371 - 1.4.1.2 0.000000000000009225 78.0
MMD2_k127_5933718_0 Nickel-dependent hydrogenase K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 589.0
MMD2_k127_5933718_1 -binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003243 410.0
MMD2_k127_5933718_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000157 293.0
MMD2_k127_5933718_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000008958 242.0
MMD2_k127_5933718_4 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000003249 206.0
MMD2_k127_5933718_5 PFAM NADH ubiquinone oxidoreductase, 20 K18007 - 1.12.1.2 0.000000000000000000000000000000000000000000005278 169.0
MMD2_k127_5995139_0 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000002331 162.0
MMD2_k127_5995139_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000004057 125.0
MMD2_k127_5995139_2 PFAM HD domain - - - 0.0000000000000000000005505 109.0
MMD2_k127_5995139_3 Helix-turn-helix XRE-family like proteins - - - 0.00000000000002916 85.0
MMD2_k127_5995139_5 PFAM CoA-transferase family III K18702 - 2.8.3.19 0.00000000002421 65.0
MMD2_k127_5995139_6 - - - - 0.0000000004143 63.0
MMD2_k127_5995139_7 Bacterial regulatory proteins, luxR family K07684 - - 0.0000000008591 70.0
MMD2_k127_6022696_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 1.172e-299 932.0
MMD2_k127_6022696_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 527.0
MMD2_k127_6022696_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 436.0
MMD2_k127_6022696_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002824 275.0
MMD2_k127_6022696_4 PFAM Enoyl-CoA hydratase isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000139 265.0
MMD2_k127_6022696_5 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000009373 185.0
MMD2_k127_6022696_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000001539 123.0
MMD2_k127_6022696_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000003579 105.0
MMD2_k127_6022696_8 - - - - 0.0000000000000000000002104 102.0
MMD2_k127_6022696_9 Glyoxalase-like domain K01759,K05606 - 4.4.1.5,5.1.99.1 0.000000000000000000001012 99.0
MMD2_k127_6028330_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 566.0
MMD2_k127_6028330_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 369.0
MMD2_k127_6028330_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 329.0
MMD2_k127_6028330_3 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 287.0
MMD2_k127_6028330_4 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000009988 153.0
MMD2_k127_6028330_5 Type IV pilus biogenesis stability protein PilW - - - 0.0000000000000000000000003329 111.0
MMD2_k127_6118705_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 442.0
MMD2_k127_6118705_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 372.0
MMD2_k127_6118705_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000002493 270.0
MMD2_k127_6118705_3 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000001531 224.0
MMD2_k127_6118705_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000001318 187.0
MMD2_k127_6118705_5 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000001401 149.0
MMD2_k127_6118705_6 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000003201 133.0
MMD2_k127_6118705_7 - - - - 0.0000000001035 67.0
MMD2_k127_6119617_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 299.0
MMD2_k127_6119617_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000003841 134.0
MMD2_k127_6119617_2 Alpha/beta hydrolase family - - - 0.00000000000584 76.0
MMD2_k127_6151910_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.151e-229 734.0
MMD2_k127_6151910_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 505.0
MMD2_k127_6151910_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 469.0
MMD2_k127_6151910_3 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 294.0
MMD2_k127_6151910_4 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002778 226.0
MMD2_k127_6151910_5 SMART HNH nuclease - - - 0.00000000000000000000000000000000000000000000000002209 185.0
MMD2_k127_6151910_6 Chromatin associated protein KTI12 - - - 0.0000000000000000000000000164 116.0
MMD2_k127_6151910_7 PFAM Biotin lipoyl attachment - - - 0.00000000000000298 83.0
MMD2_k127_6151910_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000001965 76.0
MMD2_k127_6256192_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 550.0
MMD2_k127_6256192_1 metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007679 367.0
MMD2_k127_6256192_2 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 319.0
MMD2_k127_6256192_3 histidine kinase HAMP region domain protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000356 268.0
MMD2_k127_6256192_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001261 251.0
MMD2_k127_6256192_5 PFAM Signal transduction histidine kinase, subgroup 2, dimerisation and phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000000001806 244.0
MMD2_k127_6256192_7 Ion channel - - - 0.00006318 53.0
MMD2_k127_695630_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 5.817e-222 702.0
MMD2_k127_695630_1 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005352 425.0
MMD2_k127_695630_2 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 347.0
MMD2_k127_73688_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000898 186.0
MMD2_k127_73688_1 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000001305 161.0
MMD2_k127_73688_2 histidine kinase, dimerisation and phosphoacceptor region K02480 - 2.7.13.3 0.0000000000000000000000000000000806 144.0
MMD2_k127_73688_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 0.00000000000000000003145 99.0
MMD2_k127_73688_5 Polyprenyl synthetase - - - 0.00000000007214 74.0
MMD2_k127_73688_6 - - - - 0.000003766 56.0
MMD2_k127_738526_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 316.0
MMD2_k127_738526_1 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 299.0
MMD2_k127_738526_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000003045 201.0
MMD2_k127_738526_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase - - - 0.000000000000000000000004998 109.0
MMD2_k127_738526_4 NAD(P)H dehydrogenase (quinone) activity - - - 0.00000000000002803 81.0
MMD2_k127_765930_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003403 283.0
MMD2_k127_765930_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000447 222.0
MMD2_k127_765930_2 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000002846 130.0
MMD2_k127_765930_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000004554 109.0
MMD2_k127_783384_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 392.0
MMD2_k127_783384_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 330.0
MMD2_k127_783384_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000006404 166.0
MMD2_k127_787101_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 4.667e-207 655.0
MMD2_k127_787101_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008769 480.0
MMD2_k127_787101_2 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 443.0
MMD2_k127_787101_3 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000005921 240.0
MMD2_k127_787101_4 LysE type translocator - - - 0.00000000000000000000000000000000000004092 151.0
MMD2_k127_787101_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006437,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000003333 74.0
MMD2_k127_788811_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007387 289.0
MMD2_k127_788811_1 TPR repeat - - - 0.0000000000000000000000000000000000000000001097 170.0
MMD2_k127_788811_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000005473 147.0
MMD2_k127_788811_3 PFAM Alpha beta hydrolase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000009291 130.0
MMD2_k127_788811_4 Belongs to the 4-oxalocrotonate tautomerase family K01821 - 5.3.2.6 0.0000000005154 62.0
MMD2_k127_788811_5 all-trans-retinol 13,14-reductase activity K09516,K09835 - 1.3.99.23,5.2.1.13 0.0000000009256 63.0
MMD2_k127_791020_0 DNA polymerase X family K02347 - - 2.04e-226 714.0
MMD2_k127_791020_1 Helix-turn-helix - - - 0.000000000000000003679 86.0
MMD2_k127_791020_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.000000002441 58.0
MMD2_k127_794129_0 PFAM glycoside hydrolase, family 3 domain protein K05349 - 3.2.1.21 1.824e-272 861.0
MMD2_k127_794129_1 ABC transporter K06147 - - 1.802e-257 812.0
MMD2_k127_794129_2 ABC transporter K06147 - - 4.351e-257 807.0
MMD2_k127_794129_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006342 386.0
MMD2_k127_794129_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 379.0
MMD2_k127_794129_5 metal-dependent phosphohydrolase HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 362.0
MMD2_k127_794129_6 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004953 320.0
MMD2_k127_794129_7 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001242 238.0
MMD2_k127_794129_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000001177 124.0
MMD2_k127_794627_0 Elongation factor G C-terminus K06207 - - 3.48e-279 869.0
MMD2_k127_794627_1 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 367.0
MMD2_k127_794627_2 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 291.0
MMD2_k127_794627_3 Protein of unknown function (DUF3795) - - - 0.0000000000000000000000000000000000000000000000001756 181.0
MMD2_k127_794627_4 - - - - 0.000000000000000000000000000000000000000001094 163.0
MMD2_k127_794627_5 acetyltransferase - - - 0.00000000000000000000000000000000000000004546 159.0
MMD2_k127_794627_6 Nitroreductase family - - - 0.000000000000000000000000000000000000002406 153.0
MMD2_k127_794627_7 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.00000000000000000002712 92.0
MMD2_k127_794627_8 Flavodoxin domain - - - 0.00000002049 61.0
MMD2_k127_806073_0 Glycosyltransferase family 20 K16055 - 2.4.1.15,3.1.3.12 1.247e-195 621.0
MMD2_k127_806073_1 Glycosyl transferases group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009861 559.0
MMD2_k127_806073_2 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 323.0
MMD2_k127_806073_3 Removes the phosphate from trehalose 6-phosphate to produce free trehalose K01087 - 3.1.3.12 0.0000000000000000000000000000000000000000002276 168.0
MMD2_k127_806073_4 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.000000000000000000000000000000001884 132.0
MMD2_k127_806073_5 - - - - 0.0000000000002365 78.0
MMD2_k127_806073_6 Transporter associated domain K03699 - - 0.0000000000005159 70.0
MMD2_k127_809867_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1571.0
MMD2_k127_809867_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1470.0
MMD2_k127_809867_10 - - - - 0.000000000000000000000000000000000000000000000729 181.0
MMD2_k127_809867_11 Protein of unknown function (DUF2889) K07053 - 3.1.3.97 0.000000000000000000000000000000000000003346 154.0
MMD2_k127_809867_12 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000002173 136.0
MMD2_k127_809867_13 von Willebrand factor type A domain K03404 - 6.6.1.1 0.0000000000000000000000000007779 125.0
MMD2_k127_809867_15 RNA polymerase II K20827 GO:0000428,GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005730,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008420,GO:0009058,GO:0009059,GO:0009301,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016073,GO:0016311,GO:0016591,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0030880,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032774,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0036211,GO:0042578,GO:0042795,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055029,GO:0060255,GO:0061695,GO:0065007,GO:0070013,GO:0070940,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:0098781,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 3.1.3.16 0.0001808 48.0
MMD2_k127_809867_2 Belongs to the ClpA ClpB family K03696 - - 0.0 1056.0
MMD2_k127_809867_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 294.0
MMD2_k127_809867_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002038 290.0
MMD2_k127_809867_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0018193,GO:0018205,GO:0019538,GO:0030312,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070490,GO:0070647,GO:0071704,GO:0071944,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000002945 231.0
MMD2_k127_809867_6 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000006087 227.0
MMD2_k127_809867_7 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000001369 222.0
MMD2_k127_809867_8 - - - - 0.000000000000000000000000000000000000000000000000000000434 202.0
MMD2_k127_809867_9 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000195 185.0
MMD2_k127_81478_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 7.291e-249 811.0
MMD2_k127_81478_1 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000006946 207.0
MMD2_k127_81478_2 PKD domain K01179,K08651 - 3.2.1.4,3.4.21.66 0.00000000000000005763 90.0
MMD2_k127_81478_3 DNA alkylation repair enzyme - - - 0.00000000004377 73.0
MMD2_k127_81478_4 PQQ enzyme repeat protein - - - 0.00000000103 68.0
MMD2_k127_828329_0 haemagglutination activity domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 362.0
MMD2_k127_828329_1 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 314.0
MMD2_k127_828329_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000003168 154.0
MMD2_k127_828329_3 Nitroreductase family - - - 0.00000000000000007997 82.0
MMD2_k127_828329_4 Acetyltransferase (GNAT) family - - - 0.0000000000000001468 85.0
MMD2_k127_828329_5 Putative regulatory protein - - - 0.000001469 53.0
MMD2_k127_844597_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.0 1519.0
MMD2_k127_844597_1 Male sterility protein K21793 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003495 453.0
MMD2_k127_844597_10 Domain of unknown function (DUF362) - - - 0.000000001095 66.0
MMD2_k127_844597_11 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00004577 51.0
MMD2_k127_844597_2 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 447.0
MMD2_k127_844597_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 440.0
MMD2_k127_844597_4 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002093 255.0
MMD2_k127_844597_5 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000009247 257.0
MMD2_k127_844597_6 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000005206 240.0
MMD2_k127_844597_7 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000007358 228.0
MMD2_k127_844597_8 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000001668 165.0
MMD2_k127_844597_9 PQ loop repeat K15383 - - 0.0000000000000000005004 89.0
MMD2_k127_856976_0 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000001791 188.0
MMD2_k127_856976_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058,K11216 - 1.1.1.399,1.1.1.95,2.7.1.189 0.00000000000000000000000000000000000008396 152.0
MMD2_k127_879858_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 266.0
MMD2_k127_879858_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000002183 162.0
MMD2_k127_879858_2 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000001518 105.0
MMD2_k127_879858_3 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 0.00000000000000000003794 103.0
MMD2_k127_879858_4 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.000000000000004901 83.0
MMD2_k127_879858_5 Guanylate kinase homologues. K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009507,GO:0009536,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040008,GO:0042278,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0048638,GO:0050145,GO:0050789,GO:0050793,GO:0055086,GO:0065007,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000001728 54.0
MMD2_k127_912722_0 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000003903 174.0
MMD2_k127_912722_1 Acyltransferase family - - - 0.0000000000000000000000000000000000000001218 158.0
MMD2_k127_912722_3 - - - - 0.00000000000002073 79.0
MMD2_k127_912722_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000004764 80.0
MMD2_k127_936493_0 beta-keto acid cleavage enzyme K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 354.0
MMD2_k127_936493_1 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007407 289.0
MMD2_k127_936493_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000004098 121.0
MMD2_k127_936493_3 - - - - 0.000000000000000000001233 103.0
MMD2_k127_938917_0 Heat shock 70 kDa protein K04043 - - 1.496e-199 626.0
MMD2_k127_938917_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01640,K01666 - 4.1.3.39,4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000167 272.0
MMD2_k127_938917_10 hydrolase K01048 - 3.1.1.5 0.00002259 49.0
MMD2_k127_938917_12 Restriction of 5-methyl and 5-hydroxymethylcytosines at the specific DNA sequence C(me)CGG K07451 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0008327,GO:0036094,GO:0043565,GO:0097159,GO:1901265,GO:1901363 - 0.0003061 48.0
MMD2_k127_938917_13 - - - - 0.0008573 46.0
MMD2_k127_938917_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001485 285.0
MMD2_k127_938917_3 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000001923 195.0
MMD2_k127_938917_4 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000003682 191.0
MMD2_k127_938917_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000000000000000001407 151.0
MMD2_k127_938917_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins - - - 0.00000000000000000000000000000000005892 146.0
MMD2_k127_938917_7 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000006057 106.0
MMD2_k127_938917_8 MarR family - - - 0.000000001124 66.0
MMD2_k127_938917_9 Heat shock 70 kDa protein K04043 - - 0.000007034 51.0
MMD2_k127_995012_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.778e-233 727.0
MMD2_k127_995012_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.253e-222 698.0
MMD2_k127_995012_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 349.0
MMD2_k127_995012_3 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000009921 138.0
MMD2_k127_995012_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000009154 132.0
MMD2_k127_995012_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000005559 117.0
MMD2_k127_995012_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000008732 101.0
MMD2_k127_995012_7 KH domain K06960 - - 0.00000000000000002917 83.0
MMD2_k127_995012_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000002283 78.0