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Overview

ID MAG02366
Name MMD2_bin.31
Sample SMP0059
Taxonomy
Kingdom Archaea
Phylum Halobacteriota
Class Methanomicrobia
Order Methanomicrobiales
Family JACTUA01
Genus JAJRCL01
Species
Assembly information
Completeness (%) 78.85
Contamination (%) 2.24
GC content (%) 59.0
N50 (bp) 5,838
Genome size (bp) 1,695,411

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1839

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_100299_0 TIGRFAM acetate--CoA ligase K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 514.0
MMD2_k127_100299_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 319.0
MMD2_k127_100299_2 Transcriptional regulator, TrmB - - - 0.000000000000000000000000000000000000000000000000398 178.0
MMD2_k127_1063340_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.000000000000000000000000000000000000000000000000000000000000000003051 228.0
MMD2_k127_1063340_1 - - - - 0.000000000000000000000000000000000000000000002623 175.0
MMD2_k127_1063340_2 PFAM Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000002662 72.0
MMD2_k127_1080757_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008854 419.0
MMD2_k127_1080757_1 Acetyl-coenzyme A synthetase N-terminus K01895,K01908 GO:0003674,GO:0003824,GO:0003987,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016405,GO:0016874,GO:0016877,GO:0016878,GO:0017144,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046950,GO:0046951,GO:0070013,GO:0071704,GO:1901568,GO:1901570,GO:1901576,GO:1902224 6.2.1.1,6.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 304.0
MMD2_k127_1080757_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000006059 163.0
MMD2_k127_1080757_3 Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000001308 145.0
MMD2_k127_1080757_4 SpoVT / AbrB like domain - - - 0.00000000000000000000000000001643 120.0
MMD2_k127_10878_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009312 530.0
MMD2_k127_10878_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 424.0
MMD2_k127_10878_2 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 375.0
MMD2_k127_10878_3 Fumarase C-terminus K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000007161 258.0
MMD2_k127_10878_4 Oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000005247 252.0
MMD2_k127_10878_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000000000000000000000000000000002284 164.0
MMD2_k127_1089154_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.541e-300 947.0
MMD2_k127_1089154_1 Cell division protein 48 (CDC48), domain 2 K13525 - - 9.754e-274 863.0
MMD2_k127_1089154_2 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 2.426e-237 738.0
MMD2_k127_1089154_3 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000001015 213.0
MMD2_k127_1089154_4 5-formyltetrahydrofolate cycloligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000829 195.0
MMD2_k127_1097295_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000001379 203.0
MMD2_k127_1097295_1 - - - - 0.00000002477 67.0
MMD2_k127_1111203_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 548.0
MMD2_k127_1111203_1 signal transduction protein with CBS domains K07744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 285.0
MMD2_k127_1111203_2 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000002948 234.0
MMD2_k127_1111203_3 PFAM PRC-barrel domain - - - 0.000000000000000000000000000000000006831 138.0
MMD2_k127_1111203_4 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.000000000000000000001191 98.0
MMD2_k127_1111203_5 Histone-like transcription factor (CBF/NF-Y) and archaeal histone - - - 0.00000000000000000001472 93.0
MMD2_k127_1111203_6 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000001204 62.0
MMD2_k127_1111203_7 - - - - 0.00001507 49.0
MMD2_k127_1114591_0 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 1.327e-225 704.0
MMD2_k127_1114591_1 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 516.0
MMD2_k127_1114591_10 transcription activator, effector binding - - - 0.00000000000000000000000000004411 118.0
MMD2_k127_1114591_11 - - - - 0.00000000007678 66.0
MMD2_k127_1114591_2 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 354.0
MMD2_k127_1114591_3 O-methyltransferase K15256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002941 251.0
MMD2_k127_1114591_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005247 248.0
MMD2_k127_1114591_5 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000193 216.0
MMD2_k127_1114591_6 HAD-hyrolase-like K07025 - - 0.000000000000000000000000000000000000000000000000000000000002331 216.0
MMD2_k127_1114591_7 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000001502 204.0
MMD2_k127_1114591_8 PFAM Uncharacterised protein family (UPF0153) - - - 0.0000000000000000000000000000000000000000002157 164.0
MMD2_k127_1114591_9 small multi-drug export - - - 0.00000000000000000000000000000000000002956 151.0
MMD2_k127_1121360_0 Arginine deiminase K01478 - 3.5.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 343.0
MMD2_k127_1121360_1 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.00000000000000000000000000000000000000000000000000000000000000000002571 239.0
MMD2_k127_1134012_0 PFAM type II secretion system protein E K07332 - - 1.067e-299 937.0
MMD2_k127_1134012_1 Type II secretion system (T2SS), protein F K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 400.0
MMD2_k127_1134012_2 Type II secretion system (T2SS), protein F K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 346.0
MMD2_k127_1134012_3 - - - - 0.0000000000000000000000000000000000000000001594 165.0
MMD2_k127_1150113_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000003377 251.0
MMD2_k127_1150113_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06885 - - 0.000000000000000000000000000000000001878 141.0
MMD2_k127_1150113_2 UbiD family - - - 0.00000000000000000000000000007302 123.0
MMD2_k127_1158072_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.612e-212 671.0
MMD2_k127_1158072_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.369e-199 626.0
MMD2_k127_1158072_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 575.0
MMD2_k127_1214594_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 479.0
MMD2_k127_1215478_0 PFAM dihydropteroate synthase, DHPS - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 591.0
MMD2_k127_1215478_1 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 332.0
MMD2_k127_1215478_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000006131 264.0
MMD2_k127_1215478_3 - - - - 0.0000000000000000000000000000000000000000008581 163.0
MMD2_k127_1215478_4 - - - - 0.00000000000000000000000000005152 123.0
MMD2_k127_1215478_5 B3/4 domain - - - 0.00001153 49.0
MMD2_k127_1241121_0 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 341.0
MMD2_k127_1241121_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
MMD2_k127_1241121_2 amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000002783 215.0
MMD2_k127_1241121_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000007661 151.0
MMD2_k127_1241121_4 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000785 134.0
MMD2_k127_1251474_0 Protein of unknown function (DUF1616) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 379.0
MMD2_k127_1251474_1 - - - - 0.0000000000000000000000000000000000000000000000000000119 193.0
MMD2_k127_1251474_2 - - - - 0.0000000000000000003194 89.0
MMD2_k127_1251474_3 RDD family - - - 0.0000000002917 69.0
MMD2_k127_1251474_4 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0001088 45.0
MMD2_k127_1275245_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009528 520.0
MMD2_k127_1275245_1 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 306.0
MMD2_k127_1275245_2 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000009917 216.0
MMD2_k127_1275245_3 Alpha/beta hydrolase family K06889 - - 0.0000000000000000000000000000000000000000000000000005939 195.0
MMD2_k127_1275245_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000001849 125.0
MMD2_k127_1284164_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 1.43e-225 717.0
MMD2_k127_1284164_1 Serine dehydrogenase proteinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 320.0
MMD2_k127_1284164_2 Belongs to the PdaD family K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 312.0
MMD2_k127_1292714_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 543.0
MMD2_k127_1292714_1 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000000000000000002785 198.0
MMD2_k127_1292714_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000001105 172.0
MMD2_k127_1306243_0 SMART DNA-directed DNA polymerase B K02319 - 2.7.7.7 0.0 1142.0
MMD2_k127_1306243_1 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 360.0
MMD2_k127_1306243_2 Tetratricopeptide repeat - - - 0.000000000000000000000006518 115.0
MMD2_k127_1313423_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 385.0
MMD2_k127_1313423_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005803 295.0
MMD2_k127_1313423_2 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007861 292.0
MMD2_k127_1313423_3 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001211 280.0
MMD2_k127_1313423_4 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000000000000000000000000000000000000007629 222.0
MMD2_k127_1313423_5 Precorrin-6y C5,15-methyltransferase (Decarboxylating), CbiE subunit K03399 - 2.1.1.289 0.00000000000000000000000000000000000000000000000000002918 194.0
MMD2_k127_1313423_6 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02009 - - 0.0000000000000005139 83.0
MMD2_k127_1381111_0 rubredoxin K22405 - 1.6.3.4 0.0000000000000000000000000000000000000000000000000000000003653 219.0
MMD2_k127_1381111_1 amino acid K03294 - - 0.000000000000000000000000000000000003672 146.0
MMD2_k127_1381111_2 ABC-type sugar transport system, ATPase component K10539 - 3.6.3.17 0.00000003094 61.0
MMD2_k127_1400551_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.717e-210 668.0
MMD2_k127_1400551_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000336 388.0
MMD2_k127_1400551_2 TIGRFAM F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 348.0
MMD2_k127_1400551_3 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005246 302.0
MMD2_k127_1400551_4 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001467 263.0
MMD2_k127_1400551_5 - - - - 0.00000000000000000005389 94.0
MMD2_k127_1406338_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 314.0
MMD2_k127_1406338_1 Phosphate transport regulator K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 296.0
MMD2_k127_1406338_2 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002765 254.0
MMD2_k127_1406338_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000004589 226.0
MMD2_k127_1406338_4 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000007322 173.0
MMD2_k127_1406338_5 - K06193 - - 0.0000000000000004715 78.0
MMD2_k127_1408544_0 PFAM Multicopper oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 496.0
MMD2_k127_1413958_0 Involved in cell shape control K22222 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 444.0
MMD2_k127_1413958_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 423.0
MMD2_k127_1413958_2 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000006925 203.0
MMD2_k127_1480062_0 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 413.0
MMD2_k127_1480062_1 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 332.0
MMD2_k127_1480062_2 PFAM Glycosyl transferase family 2 K07027 - - 0.00000000000000000000000000000000000000000000000000000006131 199.0
MMD2_k127_1482240_0 PFAM Semialdehyde dehydrogenase NAD - binding K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 526.0
MMD2_k127_1482240_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 447.0
MMD2_k127_1482240_10 - - - - 0.000000001203 66.0
MMD2_k127_1482240_2 Domain of unknown function (DUF373) K08975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 451.0
MMD2_k127_1482240_3 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 370.0
MMD2_k127_1482240_4 archaeal coiled-coil protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 323.0
MMD2_k127_1482240_5 protein conserved in archaea - - - 0.000000000000000000000000000000000000000000005183 176.0
MMD2_k127_1482240_6 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000000000000000000000006925 158.0
MMD2_k127_1482240_7 - - - - 0.0000000000000000000000000000000000008198 149.0
MMD2_k127_1482240_8 4Fe-4S dicluster domain - - - 0.00000000000000001225 87.0
MMD2_k127_1482240_9 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000002656 82.0
MMD2_k127_1496186_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 449.0
MMD2_k127_1496186_1 Replication factor C K04801 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 368.0
MMD2_k127_1496186_2 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 325.0
MMD2_k127_1496186_3 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000238 243.0
MMD2_k127_1496186_4 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000000000000000000000001425 227.0
MMD2_k127_1496186_5 PFAM AIR synthase related protein K07388 - - 0.00000000000000000000003309 100.0
MMD2_k127_1496186_6 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000005932 79.0
MMD2_k127_1500781_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 290.0
MMD2_k127_1500781_1 PFAM Transmembrane exosortase (Exosortase_EpsH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 293.0
MMD2_k127_1500781_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.0000000000000000000000000000000000000000006321 159.0
MMD2_k127_1548722_0 PFAM Archaeal protein of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 545.0
MMD2_k127_1548722_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008414 278.0
MMD2_k127_1548722_2 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004432 264.0
MMD2_k127_1548722_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000343 254.0
MMD2_k127_1548722_4 PFAM Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000001026 218.0
MMD2_k127_1548722_5 Phosphoribosyl transferase domain K07101 - - 0.000000000000000000000000000000000000000000000000000000000000821 216.0
MMD2_k127_1548722_6 - - - - 0.000000000000000000000002473 108.0
MMD2_k127_1548722_7 PFAM blue (type 1) copper domain protein - - - 0.00000000007173 74.0
MMD2_k127_1548722_8 - K01448 - 3.5.1.28 0.0000000004 71.0
MMD2_k127_1575995_0 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 445.0
MMD2_k127_1575995_1 PFAM Exonuclease VII large subunit K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003202 378.0
MMD2_k127_1575995_2 archaeal Zn-finger protein - - - 0.000000000000000000000000000000000000000000000000000000006998 205.0
MMD2_k127_1575995_3 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000000000000000000000007397 173.0
MMD2_k127_1575995_4 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000003116 160.0
MMD2_k127_1575995_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000001141 143.0
MMD2_k127_1575995_6 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000003748 132.0
MMD2_k127_1575995_7 - - - - 0.0000000000000000000002008 108.0
MMD2_k127_1617409_0 - - - - 0.000000000000002994 90.0
MMD2_k127_1617409_1 PFAM Glycosyl transferase family 2 - - - 0.000000000002025 72.0
MMD2_k127_1672720_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009525 292.0
MMD2_k127_1672720_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000001385 214.0
MMD2_k127_1672720_2 Epoxide hydrolase K01253 - 3.3.2.9 0.0000205 50.0
MMD2_k127_1680861_0 PFAM ABC transporter K16787 - - 0.0000000000000000000000000000000000000000000000000000000000022 216.0
MMD2_k127_1680861_1 - K16785 - - 0.0000000000000000000000000000000000000817 149.0
MMD2_k127_1680861_2 PFAM ABC transporter K16786 - - 0.00000000000000000004369 92.0
MMD2_k127_172102_0 TGS domain protein K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 496.0
MMD2_k127_172102_1 - - - - 0.00000000000000000000000000000000000000004682 154.0
MMD2_k127_172102_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000001434 130.0
MMD2_k127_172102_3 - - - - 0.0000000000000000000000008065 115.0
MMD2_k127_172102_4 - - - - 0.0000000000309 68.0
MMD2_k127_1751786_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 3.647e-209 660.0
MMD2_k127_1772104_0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000002661 205.0
MMD2_k127_1772104_1 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000008962 193.0
MMD2_k127_1772104_2 - - - - 0.0000000000000005473 85.0
MMD2_k127_1773213_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 331.0
MMD2_k127_1773213_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 301.0
MMD2_k127_1773213_2 PFAM acylneuraminate cytidylyltransferase K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 289.0
MMD2_k127_1773213_3 HpcH/HpaI aldolase/citrate lyase family K00979,K02510 - 2.7.7.38,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001908 280.0
MMD2_k127_1773213_4 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00000000000000000000000001947 121.0
MMD2_k127_1773213_5 Glycosyltransferase, group 2 family protein - - - 0.00000000000000000000000006413 110.0
MMD2_k127_17880_0 Converts O-phospho-L-seryl-tRNA(Cys) (Sep-tRNA(Cys)) to L-cysteinyl-tRNA(Cys) (Cys-tRNA(Cys)) K06868 - 2.5.1.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 565.0
MMD2_k127_17880_1 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 445.0
MMD2_k127_17880_2 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single- stranded endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 427.0
MMD2_k127_17880_3 Uncharacterized protein conserved in archaea (DUF2150) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001214 241.0
MMD2_k127_17880_4 WxcM-like, C-terminal K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000001133 221.0
MMD2_k127_17880_5 COG1202 Superfamily II helicase, archaea-specific - - - 0.00000000000000000000000000000000000000000000000000003523 193.0
MMD2_k127_17880_6 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000000002963 117.0
MMD2_k127_17880_7 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000003495 87.0
MMD2_k127_17880_8 - K06868 - 2.5.1.73 0.0000000001133 63.0
MMD2_k127_17880_9 Restriction endonuclease - - - 0.00000005057 63.0
MMD2_k127_1790968_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1067.0
MMD2_k127_1801460_0 LOR SDH bifunctional enzyme conserved - - - 2.063e-195 616.0
MMD2_k127_1801460_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 578.0
MMD2_k127_1801460_2 PFAM Aminotransferase class I and II K04720 - 4.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 363.0
MMD2_k127_1801460_3 MobA-like NTP transferase domain K19712 - 2.7.7.62 0.00000000000000000000000000000000000000000000000000000002436 203.0
MMD2_k127_1801460_4 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain K07746 - - 0.000000000000000000003582 94.0
MMD2_k127_1862121_0 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 3.723e-235 735.0
MMD2_k127_1862121_1 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004381 558.0
MMD2_k127_1862121_2 COG0438 Glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 333.0
MMD2_k127_1862121_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 310.0
MMD2_k127_1862121_4 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008375 269.0
MMD2_k127_1862121_6 Domain of unknown function (DUF4282) - - - 0.00003042 50.0
MMD2_k127_1887710_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1225.0
MMD2_k127_1887710_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002045 273.0
MMD2_k127_1887710_2 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002213 258.0
MMD2_k127_1887710_3 Uncharacterized protein conserved in archaea (DUF2124) - - - 0.0000000000000000000000000000000000000000000000000000000002189 207.0
MMD2_k127_1887710_4 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000000009009 186.0
MMD2_k127_1887710_5 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000002683 123.0
MMD2_k127_1887710_6 COG0433 Predicted ATPase K06915 - - 0.00000000000000000000000003158 122.0
MMD2_k127_1889940_0 Involved in regulation of DNA replication K10725 - - 2.289e-201 632.0
MMD2_k127_1889940_1 PFAM Aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 577.0
MMD2_k127_1889940_2 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003531 251.0
MMD2_k127_1911927_0 ATPase, P-type transporting, HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.658e-257 818.0
MMD2_k127_1911927_1 Belongs to the peptidase S16 family - - - 1.446e-196 620.0
MMD2_k127_1911927_2 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 417.0
MMD2_k127_1911927_3 - - - - 0.0000568 48.0
MMD2_k127_1934654_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 404.0
MMD2_k127_1934654_1 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001267 271.0
MMD2_k127_1934654_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000009364 241.0
MMD2_k127_1934654_3 metallopeptidase activity - - - 0.00000000000000000000000000000000000000003119 155.0
MMD2_k127_1934654_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000002297 143.0
MMD2_k127_1934654_5 Proline dehydrogenase - - - 0.00000000000002199 79.0
MMD2_k127_1951588_0 Domain of unknown function (DUF4445) - - - 3.589e-234 738.0
MMD2_k127_1951588_1 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.000000000000000904 77.0
MMD2_k127_1984153_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 473.0
MMD2_k127_1984153_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000001629 228.0
MMD2_k127_1984153_2 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000000000000000000000000000000000005043 165.0
MMD2_k127_1988218_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 358.0
MMD2_k127_1988218_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001292 273.0
MMD2_k127_1988218_2 glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000006951 221.0
MMD2_k127_1988218_3 epimerase K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000001258 79.0
MMD2_k127_1990680_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 996.0
MMD2_k127_1990680_1 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 2.916e-251 781.0
MMD2_k127_1990680_2 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 6.428e-245 761.0
MMD2_k127_1990680_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001665 257.0
MMD2_k127_1990680_4 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000043 216.0
MMD2_k127_19959_0 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 443.0
MMD2_k127_19959_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 320.0
MMD2_k127_2013765_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 329.0
MMD2_k127_2013765_1 amino acid K16263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008654 282.0
MMD2_k127_2013765_2 Rubredoxin is a small nonheme, iron protein lacking acid-labile sulfide. Its single Fe, chelated to 4 Cys, functions as an electron acceptor and may also stabilize the conformation of the molecule - - - 0.00000000000000000000000000000000000000000000000007441 180.0
MMD2_k127_2044575_0 PFAM TrkA-N domain protein K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 497.0
MMD2_k127_2044575_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
MMD2_k127_2044575_2 PFAM PP-loop domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001789 265.0
MMD2_k127_2044575_3 PFAM Glucose-6-phosphate isomerase K06859 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000001666 222.0
MMD2_k127_2044575_4 Domain of unknown function DUF128 K21640 - - 0.00000000000000000000000000000000000000000000002499 172.0
MMD2_k127_2060029_0 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 4.444e-300 938.0
MMD2_k127_2060029_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030955,GO:0031420,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 445.0
MMD2_k127_2060029_2 PFAM Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000005604 199.0
MMD2_k127_2060029_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.000000000000000000000000000000000000000000000009058 178.0
MMD2_k127_206354_0 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 421.0
MMD2_k127_206354_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 403.0
MMD2_k127_206354_2 RNA methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 340.0
MMD2_k127_206354_3 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 326.0
MMD2_k127_206354_4 Nitrogen regulatory protein P-II K04751 - - 0.0000000000000000000000000000000000000001733 164.0
MMD2_k127_2085824_0 glycosyl transferase, family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000005673 229.0
MMD2_k127_2085824_1 involved in cell wall biogenesis K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000006403 206.0
MMD2_k127_2085824_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000002392 184.0
MMD2_k127_2114195_0 PFAM proteinase inhibitor I4 serpin K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 484.0
MMD2_k127_2114195_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000004073 204.0
MMD2_k127_2114195_2 Flavodoxin - - - 0.00000000000000000000000000000000000000000000000002595 184.0
MMD2_k127_2114195_3 - - - - 0.000000000000000000000000000001186 124.0
MMD2_k127_2114195_4 PFAM Ribonuclease III K03685 - 3.1.26.3 0.0000000000000000000000000002217 119.0
MMD2_k127_2114195_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000005013 81.0
MMD2_k127_2117008_0 Threonyl-tRNA synthetase K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000001012 179.0
MMD2_k127_2117008_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000002534 109.0
MMD2_k127_2117008_2 CHY zinc finger K16276 - - 0.00000009066 61.0
MMD2_k127_2127439_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 431.0
MMD2_k127_2127439_1 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 319.0
MMD2_k127_2127439_2 COG1361 S-layer domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 312.0
MMD2_k127_2127439_3 Sugar-specific transcriptional regulator TrmB - - - 0.00000000000000000000000000000000000000000000000000000000000000000006593 239.0
MMD2_k127_2127439_4 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit K01546 - 3.6.3.12 0.000000000000000000000000000000000000000000000000000000000000000008668 229.0
MMD2_k127_2127439_5 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000003879 177.0
MMD2_k127_215388_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 432.0
MMD2_k127_215388_1 Domain of unknown function (DUF1894) - - - 0.000000000000000000000000007244 111.0
MMD2_k127_215388_2 Elongator protein 3 MiaB NifB - - - 0.000000000000000001282 91.0
MMD2_k127_2163014_0 Dihydrouridine synthase (Dus) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 362.0
MMD2_k127_2163014_1 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001159 282.0
MMD2_k127_2163014_2 - - - - 0.000000000000000000000000000000000000000000000000000001841 203.0
MMD2_k127_2163014_3 Catalyzes the insertion of Co(2 ) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl- coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2 ) into sirohydrochlorin to yield Ni- sirohydrochlorin K22011 - 4.99.1.11,4.99.1.3 0.00000000000000000000000000000000000000000000000894 174.0
MMD2_k127_216402_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 8.733e-238 745.0
MMD2_k127_216402_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 335.0
MMD2_k127_216402_2 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000006465 262.0
MMD2_k127_216402_3 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000003733 226.0
MMD2_k127_216402_4 PIN domain of ribonuclease K07060 - - 0.000000000000000000000000000000000000000002002 160.0
MMD2_k127_216402_5 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.0000000000000000000000000000000002042 134.0
MMD2_k127_216402_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000188 121.0
MMD2_k127_2168585_0 TIR domain - - - 0.00000000000000000000000000000000000000275 165.0
MMD2_k127_2168585_1 TIR domain - - - 0.0000000000000000000000000000000000001294 160.0
MMD2_k127_2210988_0 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000593 542.0
MMD2_k127_2210988_1 Cysteine-rich small domain K08260 - 3.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 338.0
MMD2_k127_2210988_2 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003613 263.0
MMD2_k127_2210988_3 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000000000000000000000000000000000000000000000000000000000004349 209.0
MMD2_k127_2210988_4 Domain of unknown function (DUF1858) - - - 0.00000000000000000000001021 101.0
MMD2_k127_2214649_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 475.0
MMD2_k127_2214649_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002642 275.0
MMD2_k127_2219633_0 Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 458.0
MMD2_k127_2219633_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001094 355.0
MMD2_k127_2219633_2 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000033 132.0
MMD2_k127_2238871_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 510.0
MMD2_k127_2238871_1 Alpha-acetolactate decarboxylase K01575 - 4.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 327.0
MMD2_k127_2238871_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000004925 93.0
MMD2_k127_2238871_3 UPF0391 membrane protein - - - 0.0000000000002151 71.0
MMD2_k127_2238871_4 TIR domain - - - 0.000000000003905 72.0
MMD2_k127_2263221_0 Activator of Hsp90 ATPase - - - 0.0000000000000000000000000000000000000000000000000001931 195.0
MMD2_k127_2263221_1 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000007689 154.0
MMD2_k127_2263221_2 PFAM bifunctional deaminase-reductase domain protein - - - 0.000000000000000002635 89.0
MMD2_k127_2263221_3 RibD C-terminal domain K00287 - 1.5.1.3 0.00000000000000002551 87.0
MMD2_k127_2263904_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 328.0
MMD2_k127_2263904_1 - - - - 0.000000000000000000000000004653 113.0
MMD2_k127_2273803_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008173 370.0
MMD2_k127_2273803_1 methylase K00571 - 2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 344.0
MMD2_k127_2273803_2 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000004284 256.0
MMD2_k127_2273803_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000005497 253.0
MMD2_k127_2273803_4 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000001012 80.0
MMD2_k127_2273803_5 Tripartite tricarboxylate transporter TctA family K08971 - - 0.000001183 52.0
MMD2_k127_232266_0 Domain of unknown function (DUF3821) - - - 3.614e-197 640.0
MMD2_k127_232266_1 Tripartite tricarboxylate transporter TctA family K08971 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 383.0
MMD2_k127_232266_2 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 368.0
MMD2_k127_232266_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 363.0
MMD2_k127_232266_4 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000000000000000000000002208 235.0
MMD2_k127_232266_5 Protein of unknown function (DUF1614) - - - 0.0000000000000000000000000000000000000000000000000000000000000000235 234.0
MMD2_k127_232266_6 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.00000000000000000000000000000000000000000000000000000000001881 218.0
MMD2_k127_2328573_0 - K14093 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002886 241.0
MMD2_k127_2328573_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000003498 111.0
MMD2_k127_2328573_2 Predicted membrane protein (DUF2107) K14096 - - 0.00000000000000000000002234 105.0
MMD2_k127_2328573_3 Predicted membrane protein (DUF2109) K14094 - - 0.0000000000000000003373 98.0
MMD2_k127_2328573_4 PFAM NiFe -hydrogenase-3-type complex Eha, membrane protein EhaF K14097 - - 0.000000000000000008215 89.0
MMD2_k127_2328573_5 Predicted membrane protein (DUF2108) K14095 - - 0.00000000000000364 82.0
MMD2_k127_2339334_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1152.0
MMD2_k127_2339334_1 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00125 - 1.17.1.9 1.714e-199 626.0
MMD2_k127_2339334_2 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000175 249.0
MMD2_k127_2339334_3 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000001481 231.0
MMD2_k127_2339334_4 PFAM TPR repeat-containing protein - - - 0.0000000000000000000473 94.0
MMD2_k127_2345845_0 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 410.0
MMD2_k127_2345845_1 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 355.0
MMD2_k127_2345845_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 315.0
MMD2_k127_2345845_3 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000002917 182.0
MMD2_k127_2345845_4 Involved in protein export. The function of the beta subunit is - GO:0003674,GO:0005085,GO:0005086,GO:0005488,GO:0005515,GO:0008150,GO:0019899,GO:0051020,GO:0065007,GO:0065009,GO:0098772 - 0.000000000000003777 75.0
MMD2_k127_2351064_0 MoeA domain protein domain I and II K03750,K07219 - 2.10.1.1 2.064e-195 622.0
MMD2_k127_2351064_1 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 390.0
MMD2_k127_2351064_2 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 344.0
MMD2_k127_2351064_3 - - - - 0.000000000000002508 77.0
MMD2_k127_2351064_4 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000001656 77.0
MMD2_k127_2353262_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000174 273.0
MMD2_k127_2353262_1 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000002242 215.0
MMD2_k127_2353262_2 COG1881 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000009624 181.0
MMD2_k127_2353262_3 SNARE associated Golgi protein K03975 - - 0.00000000000000000000000000000000000000000000221 173.0
MMD2_k127_2353262_4 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000003059 123.0
MMD2_k127_2353262_5 COG0457 FOG TPR repeat - - - 0.000000000000002998 89.0
MMD2_k127_2353262_6 Domain of unknown function (DUF4405) - - - 0.00002439 51.0
MMD2_k127_2355133_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 342.0
MMD2_k127_2355133_1 PFAM Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000001863 259.0
MMD2_k127_2355133_2 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000006665 225.0
MMD2_k127_2355133_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000533 70.0
MMD2_k127_2356723_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 8.616e-194 611.0
MMD2_k127_2356723_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000005185 190.0
MMD2_k127_2356723_2 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000006516 51.0
MMD2_k127_2373737_0 cellulose binding K01179,K21449 - 3.2.1.4 0.0000000000000000000000273 106.0
MMD2_k127_2373737_1 response regulator, receiver K09763 - - 0.000000000005922 72.0
MMD2_k127_2373737_2 Phenazine biosynthesis-like protein - - - 0.000000001509 59.0
MMD2_k127_2375873_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.065e-213 672.0
MMD2_k127_2375873_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 395.0
MMD2_k127_2375873_2 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000004063 176.0
MMD2_k127_2375873_3 - - - - 0.000000000000000000000006651 108.0
MMD2_k127_2378883_0 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 1.729e-287 892.0
MMD2_k127_2378883_1 Carbamoyl-phosphate synthetase large chain domain protein K01959 - 6.4.1.1 5.536e-243 758.0
MMD2_k127_2378883_2 PAS domain - - - 0.00009551 44.0
MMD2_k127_2387699_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 7.271e-237 744.0
MMD2_k127_2387699_1 Uncharacterized protein conserved in archaea (DUF2117) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 344.0
MMD2_k127_2387699_2 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009536 262.0
MMD2_k127_2387699_3 - - - - 0.000000000000000000000001568 104.0
MMD2_k127_2387699_4 Catalyzes the reversible phosphorylation of UMP to UDP K00947 - - 0.000000000000000000002161 102.0
MMD2_k127_2387699_5 - - - - 0.000000000000008709 81.0
MMD2_k127_2387699_6 - - - - 0.00000000000004884 80.0
MMD2_k127_2387699_7 - - - - 0.000000000005273 68.0
MMD2_k127_2406093_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009878 278.0
MMD2_k127_2406093_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000002208 216.0
MMD2_k127_2418180_0 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 291.0
MMD2_k127_2418180_1 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001065 236.0
MMD2_k127_2418180_2 Protein of unknown function (DUF1428) - - - 0.0000000000000000000000000000000000000000000009635 168.0
MMD2_k127_2418180_3 PFAM alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000001348 158.0
MMD2_k127_2427907_0 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 529.0
MMD2_k127_2427907_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004505 454.0
MMD2_k127_2427907_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000002889 177.0
MMD2_k127_2427907_3 - - - - 0.00000000000000000000000003847 122.0
MMD2_k127_2427907_4 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000002174 75.0
MMD2_k127_2436690_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002507 254.0
MMD2_k127_2436690_1 Archaebacterial flagellin K07330 - - 0.0000000000000000000000000000000000000000000000217 175.0
MMD2_k127_2436690_2 Archaeal flagellar protein F K07329 - - 0.000000000000000000000000000000000000000003116 160.0
MMD2_k127_2452267_0 DEAD DEAH box helicase K06877 - - 1.855e-281 884.0
MMD2_k127_2452267_1 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000000006098 196.0
MMD2_k127_2456836_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000002215 176.0
MMD2_k127_2456836_1 - - - - 0.00000000000000000000000000000276 127.0
MMD2_k127_2456836_2 Belongs to the UPF0215 family K09120 - - 0.000000308 53.0
MMD2_k127_2459810_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 614.0
MMD2_k127_2459810_1 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004098 394.0
MMD2_k127_2459810_11 endonuclease III K01247 - 3.2.2.21 0.000000005631 67.0
MMD2_k127_2459810_12 AN1-like Zinc finger K07059 - - 0.0004271 50.0
MMD2_k127_2459810_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 346.0
MMD2_k127_2459810_3 permease K03299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 352.0
MMD2_k127_2459810_4 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 317.0
MMD2_k127_2459810_5 extracellular matrix structural constituent - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 313.0
MMD2_k127_2459810_6 Pas domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007935 241.0
MMD2_k127_2459810_7 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000002018 186.0
MMD2_k127_2459810_8 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000002395 164.0
MMD2_k127_2459810_9 Diguanylate cyclase - - - 0.00000000000000000000000000000000007422 152.0
MMD2_k127_2494495_0 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 432.0
MMD2_k127_2494495_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K11645,K16306 - 2.2.1.10,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 430.0
MMD2_k127_2494495_2 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000104 126.0
MMD2_k127_2510316_0 PFAM DEAD_2 domain protein K10844 - 3.6.4.12 2.483e-263 827.0
MMD2_k127_2510316_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.331e-194 617.0
MMD2_k127_2510316_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 375.0
MMD2_k127_2510316_3 PFAM asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 338.0
MMD2_k127_2510316_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
MMD2_k127_2510316_5 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000008163 212.0
MMD2_k127_2510316_6 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000004324 180.0
MMD2_k127_2510316_7 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.000000000000000000000000000000000001656 149.0
MMD2_k127_2510316_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000002968 101.0
MMD2_k127_2516132_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 549.0
MMD2_k127_2516132_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 357.0
MMD2_k127_2516132_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 335.0
MMD2_k127_2516132_3 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 - 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 336.0
MMD2_k127_2516132_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000002144 85.0
MMD2_k127_2519951_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001348 266.0
MMD2_k127_2519951_1 - - - - 0.00000000000000000000000000000000000000000000000000000001358 212.0
MMD2_k127_2519951_2 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000000000000000000000000000000000151 181.0
MMD2_k127_2519951_3 Methyltransferase domain - - - 0.00000000000000000000000000000000001239 141.0
MMD2_k127_2519951_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000004214 114.0
MMD2_k127_2544439_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 2.813e-209 672.0
MMD2_k127_2544439_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 523.0
MMD2_k127_2544439_10 - - - - 0.0000001674 62.0
MMD2_k127_2544439_2 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 371.0
MMD2_k127_2544439_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004753 274.0
MMD2_k127_2544439_4 Thioredoxin - - - 0.000000000000000000000000000000000000000005366 158.0
MMD2_k127_2544439_5 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000000000002919 151.0
MMD2_k127_2544439_7 - - - - 0.0000000000000000000000000000008646 130.0
MMD2_k127_2544439_8 - - - - 0.0000000000000000000001457 109.0
MMD2_k127_2544439_9 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000001871 59.0
MMD2_k127_2566519_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 4.493e-235 734.0
MMD2_k127_2566519_1 Integral membrane protein DUF92 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 395.0
MMD2_k127_2566519_2 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 286.0
MMD2_k127_2566519_3 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000001314 220.0
MMD2_k127_2566519_4 Stage II sporulation protein M - - - 0.00000000000000000000000000000000000000000005118 173.0
MMD2_k127_2566519_5 TGS domain protein K06942 - - 0.0000003622 52.0
MMD2_k127_2586010_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 1.532e-279 871.0
MMD2_k127_2586010_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.000000000000000000000000000000000000000000003442 167.0
MMD2_k127_2594834_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 6.938e-194 625.0
MMD2_k127_2594834_1 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009475 280.0
MMD2_k127_2594834_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002772 273.0
MMD2_k127_2594834_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000001831 214.0
MMD2_k127_2594834_4 Lysine exporter protein LysE YggA - - - 0.000000000000000000000000000000000000000000000001441 179.0
MMD2_k127_2594834_5 - - - - 0.000000000000000000000000000003468 128.0
MMD2_k127_2594834_6 - - - - 0.0001689 46.0
MMD2_k127_2604028_0 PFAM Osmosensitive K channel His kinase sensor K07646 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 476.0
MMD2_k127_2604028_1 TIR domain - - - 0.0007843 43.0
MMD2_k127_2604572_0 Uncharacterized protein conserved in archaea (DUF2193) - - - 5.016e-256 796.0
MMD2_k127_2604572_1 Uncharacterized protein conserved in archaea (DUF2180) - - - 0.00000000000267 72.0
MMD2_k127_2604572_2 SMART zinc finger, CDGSH-type domain protein - - - 0.0000000000104 74.0
MMD2_k127_2604572_3 Double zinc ribbon - - - 0.0008313 49.0
MMD2_k127_2615013_0 DEAD DEAH box helicase domain protein K03724 - - 0.0 1233.0
MMD2_k127_2615013_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 5.086e-290 898.0
MMD2_k127_2615013_2 sensor histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 333.0
MMD2_k127_2615013_3 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 305.0
MMD2_k127_2615013_4 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 289.0
MMD2_k127_2615013_5 protein conserved in archaea K09746 - - 0.0009065 44.0
MMD2_k127_2657222_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 595.0
MMD2_k127_2657222_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 518.0
MMD2_k127_2657222_2 Belongs to the UPF0285 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 411.0
MMD2_k127_2657222_3 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007569 270.0
MMD2_k127_2657222_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.00000000000000000000000000000000003231 137.0
MMD2_k127_2666493_0 Belongs to the glutamate synthase family - - - 2.634e-264 821.0
MMD2_k127_2666493_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 608.0
MMD2_k127_2666493_10 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.000000000000000000002239 97.0
MMD2_k127_2666493_2 PFAM glutamine amidotransferase, class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 574.0
MMD2_k127_2666493_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 550.0
MMD2_k127_2666493_4 Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 415.0
MMD2_k127_2666493_5 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 437.0
MMD2_k127_2666493_6 PFAM glutamate synthase alpha subunit domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 334.0
MMD2_k127_2666493_7 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 332.0
MMD2_k127_2666493_8 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000003862 193.0
MMD2_k127_2666493_9 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.00000000000000000000008111 100.0
MMD2_k127_2691383_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 391.0
MMD2_k127_2691383_1 Membrane protein of unknown function DUF63 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 353.0
MMD2_k127_270055_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 415.0
MMD2_k127_270055_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 312.0
MMD2_k127_270055_2 Domain of unknown function DUF128 K21640 - - 0.000000000000000000000000000000000000000000001674 168.0
MMD2_k127_2713261_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 588.0
MMD2_k127_2713261_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 582.0
MMD2_k127_2713261_2 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000000002325 163.0
MMD2_k127_2728181_0 - - - - 0.000000000000000000000000002371 115.0
MMD2_k127_2728181_1 Domain present in carbohydrate binding proteins and sugar hydrolses - - - 0.000000000000000003284 93.0
MMD2_k127_2728181_2 - - - - 0.00000006845 58.0
MMD2_k127_2764092_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 528.0
MMD2_k127_2764092_1 Uncharacterised protein family UPF0058 - - - 0.000000000000000000000000000000000000000002888 156.0
MMD2_k127_2764092_2 Belongs to the UPF0235 family K09131 - - 0.0000000000000000000009725 99.0
MMD2_k127_2773292_0 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 351.0
MMD2_k127_2773292_1 Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K02303 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 338.0
MMD2_k127_2773292_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000002546 104.0
MMD2_k127_2773292_3 small multi-drug export - - - 0.0000007273 59.0
MMD2_k127_2788431_0 PFAM phosphoesterase, RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 612.0
MMD2_k127_2788431_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 424.0
MMD2_k127_2788431_2 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000924 414.0
MMD2_k127_2788431_3 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 317.0
MMD2_k127_2788431_4 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000000000000000000008201 214.0
MMD2_k127_2788431_5 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000000000000000000001509 147.0
MMD2_k127_2788431_6 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K07398,K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000276 71.0
MMD2_k127_280705_0 PFAM AIR synthase related protein K07388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 494.0
MMD2_k127_280705_1 PFAM Phosphomethylpyrimidine kinase type-1 K00941,K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000001083 166.0
MMD2_k127_2849942_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001233 295.0
MMD2_k127_2853878_0 Orotidine 5'-phosphate decarboxylase K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 527.0
MMD2_k127_2853878_1 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 302.0
MMD2_k127_2853878_2 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 304.0
MMD2_k127_2853878_3 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002647 270.0
MMD2_k127_2853878_4 - - - - 0.000002282 55.0
MMD2_k127_2853878_5 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00004836 53.0
MMD2_k127_288272_0 PFAM amino acid permease-associated region K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003018 271.0
MMD2_k127_288272_1 Alpha/beta hydrolase family K06889 - - 0.00000000000000000004723 91.0
MMD2_k127_2890686_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 427.0
MMD2_k127_2890686_1 TIGRFAM mannose-1-phosphate guanylyltransferase mannose-6-phosphate isomerase K16011 - 2.7.7.13,5.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 377.0
MMD2_k127_289195_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 2.698e-203 642.0
MMD2_k127_289195_1 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000002874 206.0
MMD2_k127_2901397_0 PFAM ATPase, BadF BadG BcrA BcrD type - - - 5.841e-210 658.0
MMD2_k127_2901397_1 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.000000000000001143 81.0
MMD2_k127_2949604_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006223 435.0
MMD2_k127_2949604_1 PFAM Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000002556 159.0
MMD2_k127_2949604_2 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000008209 124.0
MMD2_k127_2949604_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000003123 113.0
MMD2_k127_2949604_4 - - - - 0.000000000000000003471 87.0
MMD2_k127_2949604_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000001249 63.0
MMD2_k127_2949604_6 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000001223 57.0
MMD2_k127_2949604_7 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000004563 59.0
MMD2_k127_2949604_8 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000007341 54.0
MMD2_k127_2950853_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 3.095e-317 983.0
MMD2_k127_2950853_1 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 584.0
MMD2_k127_2950853_2 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 474.0
MMD2_k127_2950853_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 282.0
MMD2_k127_2950853_4 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.0000000000000000000000000000000000000000000005697 172.0
MMD2_k127_2950853_5 Hydrogenase maturation protease K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.00000000000000000000000000000000000000001928 160.0
MMD2_k127_2950853_6 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K00338 - 1.6.5.3 0.0000000000000000000000000000001081 133.0
MMD2_k127_2953951_0 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 450.0
MMD2_k127_2953951_1 WD-40 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 355.0
MMD2_k127_2953951_2 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000004294 205.0
MMD2_k127_2953951_3 DNA polymerase activity K02319 - 2.7.7.7 0.00000000000000000000000000000001471 132.0
MMD2_k127_2953951_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000000000002988 90.0
MMD2_k127_2953951_5 Protein of unknown function (DUF2997) - - - 0.00002197 50.0
MMD2_k127_2957944_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of Ni- sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source K22012 - 6.3.5.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 603.0
MMD2_k127_2957944_1 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 476.0
MMD2_k127_2957944_2 PFAM Mur ligase, middle domain protein K21612 - 6.4.1.9 0.0000000000000000000000000000000000000000000001428 173.0
MMD2_k127_2957944_3 Methanogenesis marker 13 metalloprotein K21611 - 6.3.3.7 0.00000000000000004403 81.0
MMD2_k127_2957944_4 - - - - 0.00000000000001478 80.0
MMD2_k127_2969489_0 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 562.0
MMD2_k127_2969489_1 Belongs to the peptidase M24B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 541.0
MMD2_k127_2969489_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 420.0
MMD2_k127_2969489_3 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 413.0
MMD2_k127_2969489_4 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 342.0
MMD2_k127_2969489_5 Nitrite and sulphite reductase 4Fe-4S - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 297.0
MMD2_k127_2969489_6 membrane K09167 - - 0.000000000000000000000000000000000000000000000000009574 189.0
MMD2_k127_2969489_7 membrane protein (DUF2178) - - - 0.000000000000000000000000000005503 124.0
MMD2_k127_2969489_8 Ferric reductase like transmembrane component - - - 0.000000000000000000000008044 109.0
MMD2_k127_2969489_9 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K03733,K04763 - - 0.000000000000004192 75.0
MMD2_k127_298348_0 PFAM 4Fe-4S - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 351.0
MMD2_k127_298348_1 PFAM DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 311.0
MMD2_k127_298348_2 Protein of unknown function (DUF1697) - - - 0.000000000000000000000000000000000000000000001887 170.0
MMD2_k127_298348_3 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000000000000000000000003137 145.0
MMD2_k127_298348_4 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000003259 111.0
MMD2_k127_298348_5 COG1246 N-acetylglutamate synthase and related acetyltransferases K00619 - 2.3.1.1 0.0000000000000000000008514 98.0
MMD2_k127_298348_6 Chagasin family peptidase inhibitor I42 K14475 - - 0.000000000000000003843 96.0
MMD2_k127_298348_7 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.00005941 48.0
MMD2_k127_3010322_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1444.0
MMD2_k127_3010322_1 tRNAHis guanylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000004933 235.0
MMD2_k127_3058456_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 370.0
MMD2_k127_3058456_1 TfuA-like protein - - - 0.00000000000000000000000000000000000000000000004087 177.0
MMD2_k127_3065086_0 PFAM Cytochrome c assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000003445 228.0
MMD2_k127_3065086_1 Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000199 160.0
MMD2_k127_3065086_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000003811 61.0
MMD2_k127_3113154_0 KH, type 1, domain K07041 - - 0.0 1085.0
MMD2_k127_3123787_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 4.607e-289 894.0
MMD2_k127_3123787_1 PFAM Methyl-coenzyme M reductase, beta subunit K00401 - 2.8.4.1 2.651e-217 680.0
MMD2_k127_3123787_2 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 361.0
MMD2_k127_3123787_3 PFAM Methyl-coenzyme M reductase, protein D K03422 - - 0.0000000000000000000000000008708 116.0
MMD2_k127_3144191_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 599.0
MMD2_k127_3144191_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 601.0
MMD2_k127_3144191_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 549.0
MMD2_k127_3144191_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 522.0
MMD2_k127_3144191_4 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 334.0
MMD2_k127_3144191_5 Desulfoferrodoxin, N-terminal domain K05919 - 1.15.1.2 0.000000000000000000000000000000006092 140.0
MMD2_k127_3144191_6 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000008827 102.0
MMD2_k127_3144191_7 ThiS family K03636 - - 0.0000001315 56.0
MMD2_k127_3152627_0 Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 308.0
MMD2_k127_3152627_1 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000000000000000000000000009935 170.0
MMD2_k127_3152627_2 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.00000000002275 64.0
MMD2_k127_3221705_0 The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex, which has 2 components the iron protein and the molybdenum-iron protein K02588 - 1.18.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 342.0
MMD2_k127_3221705_1 RibD C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000008932 189.0
MMD2_k127_3222212_0 Methanogenesis marker protein 8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 318.0
MMD2_k127_3222212_1 Protein of unknown function (DUF1624) - - - 0.0000000000000000000000000000000000000000000000000003438 193.0
MMD2_k127_3222212_2 TIGRFAM PAS sensor protein - - - 0.000000000000000000000000000003587 125.0
MMD2_k127_3222212_3 Cytochrome C biogenesis protein - - - 0.000000000000000000007407 108.0
MMD2_k127_3222212_4 HEAT repeat - - - 0.0000000000000006987 89.0
MMD2_k127_3226771_0 PFAM Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 2.342e-266 845.0
MMD2_k127_3226771_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 453.0
MMD2_k127_3228975_0 PFAM NAD(P) transhydrogenase, beta subunit K00325 - 1.6.1.2 5.4e-231 722.0
MMD2_k127_3228975_1 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 509.0
MMD2_k127_3228975_2 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005358 340.0
MMD2_k127_3228975_3 PFAM Linocin_M18 bacteriocin protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
MMD2_k127_3228975_4 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000000000000000000000000000000000000000000000000000000000006944 226.0
MMD2_k127_3228975_5 Rubrerythrin - - - 0.0000000000000000000000000000000000000000008816 159.0
MMD2_k127_3228975_6 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000002023 126.0
MMD2_k127_3228975_7 PFAM thioesterase superfamily K02614 - - 0.000000000000000000000000000006486 124.0
MMD2_k127_3228975_8 COG0438 Glycosyltransferase - - - 0.000000000000000000006799 94.0
MMD2_k127_3232512_0 PFAM NADH-ubiquinone oxidoreductase, chain 49kDa K14106 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006127 264.0
MMD2_k127_3232512_1 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003357 252.0
MMD2_k127_3232512_2 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K14101 - - 0.000000000000000000000000000000000000000000000128 171.0
MMD2_k127_3232512_3 PFAM NiFe -hydrogenase-3-type complex Eha, EhaM K14104 - - 0.0000000000000002396 85.0
MMD2_k127_3232512_4 - - - - 0.00006094 49.0
MMD2_k127_3237908_0 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04068 - 1.97.1.4 0.00000000000000000000000000000000000000004376 159.0
MMD2_k127_3237908_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000006765 150.0
MMD2_k127_3246024_0 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 373.0
MMD2_k127_3246024_1 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.00000000000000000000000000000005439 129.0
MMD2_k127_3246024_2 protein N-acetylglucosaminyltransferase activity K12600 - - 0.000000000000000000000000003196 118.0
MMD2_k127_3247147_0 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 9.447e-214 668.0
MMD2_k127_3247147_1 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 4.646e-196 615.0
MMD2_k127_3247147_2 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000003934 134.0
MMD2_k127_3253152_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 529.0
MMD2_k127_3253152_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 414.0
MMD2_k127_3253152_2 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000002967 165.0
MMD2_k127_3253152_3 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000005218 125.0
MMD2_k127_3253152_4 CARDB - - - 0.00000000000000000000001039 118.0
MMD2_k127_325864_0 DEAD DEAH box helicase domain protein K10896 - - 5.851e-252 792.0
MMD2_k127_325864_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 1.587e-210 664.0
MMD2_k127_3313460_0 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 476.0
MMD2_k127_3313460_1 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005955 331.0
MMD2_k127_3314057_0 Belongs to the UPF0284 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 430.0
MMD2_k127_3314057_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005064 271.0
MMD2_k127_3314057_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000003743 222.0
MMD2_k127_3314057_3 PFAM Phosphatidylglycerophosphatase A - - - 0.0000000000000000000000000000000000000000000000000002561 188.0
MMD2_k127_3314057_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000004068 121.0
MMD2_k127_3328548_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 555.0
MMD2_k127_3328548_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000001226 267.0
MMD2_k127_3328548_2 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000003405 237.0
MMD2_k127_3328548_3 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000007729 218.0
MMD2_k127_3334435_0 Thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 574.0
MMD2_k127_3334435_1 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 541.0
MMD2_k127_3334435_10 SMART Excinuclease ABC, C subunit - - - 0.00000000000000000000000000000000000003047 147.0
MMD2_k127_3334435_2 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11781 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 499.0
MMD2_k127_3334435_3 COG1361 S-layer domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 482.0
MMD2_k127_3334435_4 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 396.0
MMD2_k127_3334435_5 TIGRFAM riboflavin synthase K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001073 257.0
MMD2_k127_3334435_6 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008258 254.0
MMD2_k127_3334435_7 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008595 246.0
MMD2_k127_3334435_8 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000001267 227.0
MMD2_k127_3334435_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000002758 175.0
MMD2_k127_3357392_0 Nicotinic acid phosphoribosyltransferase K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 567.0
MMD2_k127_3357392_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000105 51.0
MMD2_k127_3365720_0 PFAM PUA domain containing protein K07557 - 2.6.1.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 585.0
MMD2_k127_3365720_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 - 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 578.0
MMD2_k127_3365720_2 PFAM alanine dehydrogenase PNT domain protein K00259,K00324 GO:0000286,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009987,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1,1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 565.0
MMD2_k127_3365720_3 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000004931 215.0
MMD2_k127_3365720_4 - - - - 0.000000000000000000000000000000000007308 139.0
MMD2_k127_3365720_5 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000003595 56.0
MMD2_k127_3370372_0 An RNase that has 5'-3' exonuclease activity. May be involved in RNA degradation K12574 - - 3.3e-250 777.0
MMD2_k127_3370372_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 1.548e-234 739.0
MMD2_k127_3370372_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003041 447.0
MMD2_k127_3370372_3 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 421.0
MMD2_k127_3370372_4 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 - 2.7.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008489 276.0
MMD2_k127_3370372_5 - - - - 0.00001182 53.0
MMD2_k127_3419556_0 Catalyzes the transfer of the 2-phospholactate moiety from lactyl (2) diphospho-(5')guanosine (LPPG) to 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) with the formation of the L- lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5- deazariboflavin (F420-0) and GMP K11212 - 2.7.8.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 391.0
MMD2_k127_3419556_1 Cation efflux family - - - 0.000000000000000000000000000000000000001497 151.0
MMD2_k127_3419556_2 PBS lyase K22221 - - 0.00000000000005816 78.0
MMD2_k127_3423773_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 490.0
MMD2_k127_3423773_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 424.0
MMD2_k127_3423773_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000001786 235.0
MMD2_k127_3436660_0 PFAM Aminotransferase class I and II K10206 - 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 573.0
MMD2_k127_3436660_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000954 246.0
MMD2_k127_3444505_0 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000001477 202.0
MMD2_k127_3444505_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000212 202.0
MMD2_k127_3444505_2 - - - - 0.0000000000000000000000000000003882 123.0
MMD2_k127_3444505_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000277 106.0
MMD2_k127_3444505_5 Fibronectin type 3 domain - - - 0.0000000000000005976 91.0
MMD2_k127_3446762_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 5e-324 1006.0
MMD2_k127_3446762_1 DEAD DEAH box helicase domain protein K03725 - - 2.474e-284 887.0
MMD2_k127_3446762_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000002087 233.0
MMD2_k127_3446762_11 ArsR transcriptional regulator - - - 0.000000000000000000000000000000000000002422 152.0
MMD2_k127_3446762_12 Putative adhesin - - - 0.000000000000000000000000000002434 131.0
MMD2_k127_3446762_13 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000000004259 116.0
MMD2_k127_3446762_14 Polymer-forming cytoskeletal - - - 0.0000000000000000000000509 100.0
MMD2_k127_3446762_15 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.000000000000000000004535 93.0
MMD2_k127_3446762_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006564 504.0
MMD2_k127_3446762_3 SMART regulatory protein, Crp K07730 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 384.0
MMD2_k127_3446762_4 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003229 348.0
MMD2_k127_3446762_5 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009961 337.0
MMD2_k127_3446762_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001671 277.0
MMD2_k127_3446762_7 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004866 270.0
MMD2_k127_3446762_8 COG0122 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000004051 258.0
MMD2_k127_3446762_9 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005385 239.0
MMD2_k127_3469844_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 493.0
MMD2_k127_3469844_1 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000001706 202.0
MMD2_k127_3471730_0 FHA domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 299.0
MMD2_k127_3471730_1 Right handed beta helix region - - - 0.0000000001016 71.0
MMD2_k127_3487674_0 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 386.0
MMD2_k127_3487674_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 334.0
MMD2_k127_3487674_2 Galactose oxidase, central domain - - - 0.0000000000000000000000000000000000000000000005432 192.0
MMD2_k127_3487674_3 Bacterial transferase hexapeptide (six repeats) K21379 - 2.3.1.209 0.00000000000000000000000000000000000144 144.0
MMD2_k127_3487674_4 Protein of unknown function (DUF3344) - - - 0.000000000000000000000000000000000142 155.0
MMD2_k127_3487674_5 membrane-bound metal-dependent hydrolase - - - 0.0000000000000000000000000000007239 130.0
MMD2_k127_3487674_6 Peptidase C13 family K09607 - - 0.000000000000000000000000000448 133.0
MMD2_k127_3496018_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 426.0
MMD2_k127_3496018_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 373.0
MMD2_k127_3496018_3 - - - - 0.00000001013 67.0
MMD2_k127_3548604_0 - - - - 0.0000000000000000000007406 100.0
MMD2_k127_3548604_1 Membrane - - - 0.0000000004971 62.0
MMD2_k127_3563943_0 methanogenesis marker protein 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001911 548.0
MMD2_k127_3563943_1 Protein of unknown function DUF86 - - - 0.000000000000000000000000000000000000000000000000006021 184.0
MMD2_k127_3563943_2 Nucleotidyltransferase domain K07076 - - 0.0000000000000000000000000000000000000000008407 160.0
MMD2_k127_3563943_3 PIN domain - - - 0.000000000000000000000000000002652 124.0
MMD2_k127_3563943_4 homoserine dehydrogenase K00003 - 1.1.1.3 0.00002812 46.0
MMD2_k127_3595965_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 527.0
MMD2_k127_3595965_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002439 280.0
MMD2_k127_3595965_2 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000000000000000000000000000000000000000000000000000006458 259.0
MMD2_k127_3598680_0 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 541.0
MMD2_k127_3598680_1 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 365.0
MMD2_k127_3598680_2 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 334.0
MMD2_k127_3598680_3 PAS domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002763 299.0
MMD2_k127_3598680_4 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006028 285.0
MMD2_k127_3598680_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001353 248.0
MMD2_k127_3598680_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000001587 222.0
MMD2_k127_3598680_7 - - - - 0.0000000000000000000000000000000000000000000000004044 190.0
MMD2_k127_3598680_8 Yip1 domain - - - 0.000000000000000000000000000000000000000005941 162.0
MMD2_k127_3598680_9 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000000000813 123.0
MMD2_k127_3609335_0 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 485.0
MMD2_k127_3609335_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 289.0
MMD2_k127_3615825_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 - 6.3.5.7 7.841e-254 797.0
MMD2_k127_3615825_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 582.0
MMD2_k127_3615825_10 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000002433 144.0
MMD2_k127_3615825_11 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000000000000000000000000001961 143.0
MMD2_k127_3615825_12 Family of unknown function (DUF5350) - - - 0.0000000000000000000138 100.0
MMD2_k127_3615825_13 - - - - 0.00000002969 55.0
MMD2_k127_3615825_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 531.0
MMD2_k127_3615825_3 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 425.0
MMD2_k127_3615825_4 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 374.0
MMD2_k127_3615825_5 Fe-S type, tartrate fumarate subfamily, alpha K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 380.0
MMD2_k127_3615825_6 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 341.0
MMD2_k127_3615825_7 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005441 272.0
MMD2_k127_3615825_8 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004741 261.0
MMD2_k127_3615825_9 Fumarase C-terminus K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000002686 244.0
MMD2_k127_3646627_0 PFAM Yip1 domain - - - 0.0000000000000000000000000000004271 129.0
MMD2_k127_3646627_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000002579 113.0
MMD2_k127_3646627_2 uridine kinase K00855,K00876 - 2.7.1.19,2.7.1.48 0.00000000003924 68.0
MMD2_k127_3651901_0 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 346.0
MMD2_k127_3651901_1 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 351.0
MMD2_k127_3651901_2 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 316.0
MMD2_k127_3651901_3 Sodium hydrogen exchanger K03455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 306.0
MMD2_k127_3651901_4 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004322 234.0
MMD2_k127_3651901_5 PFAM TrkA-C domain K07228 - - 0.00000000000000000000000000000000000000000000000000000000001606 209.0
MMD2_k127_3651901_6 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.0000000000000000000000000000000000000000000000000000003685 196.0
MMD2_k127_3651901_7 Protein of unknown function DUF45 K07043 - - 0.0000000000000000000000000000000000000006983 157.0
MMD2_k127_3651901_8 Prokaryotic homologs of the JAB domain - - - 0.00000000000000000000000000000000000005533 150.0
MMD2_k127_3651901_9 - - - - 0.000000005418 61.0
MMD2_k127_365458_0 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 312.0
MMD2_k127_365458_1 - - - - 0.0000000000000000000000000000004831 124.0
MMD2_k127_365458_2 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 0.0000000000000000000002443 98.0
MMD2_k127_365458_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000001322 80.0
MMD2_k127_3663181_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.177e-217 687.0
MMD2_k127_3663181_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.651e-204 647.0
MMD2_k127_3663181_2 transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 498.0
MMD2_k127_3663181_3 COG0518 GMP synthase - Glutamine amidotransferase domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000886 209.0
MMD2_k127_3663181_4 Belongs to the SUI1 family K03113 - - 0.000000000000000000000000000000000000000000000000001118 184.0
MMD2_k127_3663181_5 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000005067 120.0
MMD2_k127_3663181_6 rubredoxin - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0017144,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114,GO:0072592 - 0.00000000005611 63.0
MMD2_k127_37146_0 PFAM TatD-related deoxyribonuclease K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 350.0
MMD2_k127_37146_1 pfam nmd3 K07562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 343.0
MMD2_k127_37146_2 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 - 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000000000007909 225.0
MMD2_k127_37146_3 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000000000000000005035 127.0
MMD2_k127_37146_4 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.0000000000000001495 81.0
MMD2_k127_3729593_0 Membrane - - - 0.0000000000000000000000000000000000000000000000000002299 194.0
MMD2_k127_3729593_1 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000000000000000000000009245 130.0
MMD2_k127_3729593_2 SnoaL-like polyketide cyclase K06893 - - 0.0000000000000000000000163 105.0
MMD2_k127_3729593_4 - - - - 0.000007556 53.0
MMD2_k127_3729593_5 GYD domain - - - 0.00002301 49.0
MMD2_k127_3745822_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 7.806e-259 810.0
MMD2_k127_3745822_1 - - - - 0.000000000000000000000000000000000000000000000000000006311 196.0
MMD2_k127_3745822_2 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000000000003344 187.0
MMD2_k127_3745822_3 - - - - 0.0000000000000000000000000000000002682 138.0
MMD2_k127_376926_0 Methanogenesis marker protein 8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 403.0
MMD2_k127_376926_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000266 73.0
MMD2_k127_3774665_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 1.046e-237 749.0
MMD2_k127_3774665_1 methanogenesis marker protein 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004442 444.0
MMD2_k127_3774665_10 - - - - 0.0000000000000000761 86.0
MMD2_k127_3774665_11 PBS lyase HEAT-like repeat - - - 0.0000000000000528 80.0
MMD2_k127_3774665_12 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.0000000000002182 73.0
MMD2_k127_3774665_2 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 420.0
MMD2_k127_3774665_3 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 364.0
MMD2_k127_3774665_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008575 291.0
MMD2_k127_3774665_5 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001072 287.0
MMD2_k127_3774665_6 TIGRFAM alkylhydroperoxidase like protein, AhpD family - - - 0.000000000000000000000000000000000000000000000000000007945 195.0
MMD2_k127_3774665_7 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000001165 175.0
MMD2_k127_3774665_8 Uncharacterized protein conserved in archaea (DUF2113) - - - 0.0000000000000000000000000000000000000000000001462 171.0
MMD2_k127_3774665_9 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000007416 166.0
MMD2_k127_3822892_0 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 3.091e-297 922.0
MMD2_k127_3822892_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 554.0
MMD2_k127_3822892_2 TfuA-like protein - - - 0.0000000000000000000000000000000000000000000667 168.0
MMD2_k127_3890138_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001237 275.0
MMD2_k127_3891685_0 COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 294.0
MMD2_k127_3891685_1 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000002661 195.0
MMD2_k127_3891685_2 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000001679 175.0
MMD2_k127_3891685_3 PFAM TspO MBR family K05770 - - 0.00000000000000000000000000000000000000003486 157.0
MMD2_k127_3891685_4 Peptidase A4 family - - - 0.0000000000000000000000000000005905 136.0
MMD2_k127_3891685_5 PFAM membrane-bound metal-dependent hydrolase - - - 0.00000000000000006198 90.0
MMD2_k127_3891685_6 Magnesium transport protein CorA K03284 - - 0.00000000000000529 82.0
MMD2_k127_3891685_7 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.00000000005195 67.0
MMD2_k127_3891685_9 PFAM blue (type 1) copper domain protein K00368,K02638 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.00002037 54.0
MMD2_k127_3898833_0 DNA polymerase beta domain protein region K09717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 346.0
MMD2_k127_3898833_1 PFAM amino acid-binding ACT domain protein K06862 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 308.0
MMD2_k127_3898833_2 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000002427 242.0
MMD2_k127_3898833_3 CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000000000000000000005157 227.0
MMD2_k127_3898833_4 - - - - 0.000000000000000000000000000000000006999 149.0
MMD2_k127_3898833_5 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000001363 139.0
MMD2_k127_3898833_6 Protein of unknown function (DUF3467) - - - 0.00000000000000000000000000000000005659 139.0
MMD2_k127_3908248_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 298.0
MMD2_k127_3908248_1 Belongs to the UPF0145 family - - - 0.0000000000000000000000000000000000000000000000000001063 188.0
MMD2_k127_3908248_2 toxin activity - - - 0.0000000000000000000000000000000000000000000000000002044 195.0
MMD2_k127_3908248_3 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000000000000000000552 173.0
MMD2_k127_3908248_4 - - - - 0.0000000000000000000000000000000000000007227 152.0
MMD2_k127_3908248_5 - - - - 0.000000000000000000000000000000001777 134.0
MMD2_k127_3908248_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000002089 124.0
MMD2_k127_3908248_7 - - - - 0.0000000000000000000000000008741 117.0
MMD2_k127_3908248_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000005929 78.0
MMD2_k127_3908248_9 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000496 60.0
MMD2_k127_3973443_0 PFAM Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 595.0
MMD2_k127_3973443_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 375.0
MMD2_k127_3987822_0 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 342.0
MMD2_k127_3987822_1 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 - - 0.00000000000000000000000000000000000000000000000006424 184.0
MMD2_k127_3987822_2 - - - - 0.00000000000000000000000000000000000000005326 160.0
MMD2_k127_3987822_3 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000000000000000000000000001469 157.0
MMD2_k127_3987822_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 - - 0.00000000000001576 74.0
MMD2_k127_3987822_5 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000112 71.0
MMD2_k127_3990042_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000004457 227.0
MMD2_k127_3990042_1 ATPase, AAA superfamily - - - 0.00000000000000000000000000000000000000000000000000000448 206.0
MMD2_k127_3990042_2 PIN domain - - - 0.00000000000000000000000000000000000003228 145.0
MMD2_k127_3990042_3 Protein of unknown function DUF86 - - - 0.0000000000000000002402 95.0
MMD2_k127_3990042_4 Lamin Tail Domain K07004 - - 0.0000000000007211 81.0
MMD2_k127_3990042_5 Nucleotidyltransferase domain K07076 - - 0.000000000001954 72.0
MMD2_k127_3990042_6 Domain of unknown function (DUF4382) - - - 0.0000004329 61.0
MMD2_k127_3990042_7 PIN domain - - - 0.000006884 49.0
MMD2_k127_4043495_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 536.0
MMD2_k127_4043495_1 PFAM phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 396.0
MMD2_k127_4043495_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 365.0
MMD2_k127_4043495_3 COG0411 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 334.0
MMD2_k127_4043495_4 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 283.0
MMD2_k127_4043495_5 META domain - - - 0.000000000000000001161 94.0
MMD2_k127_4043495_6 COG0559 Branched-chain amino acid ABC-type transport system, permease components K01997,K11956 - - 0.000000000000004927 74.0
MMD2_k127_4043495_7 META domain K03668 - - 0.00001147 49.0
MMD2_k127_405733_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 562.0
MMD2_k127_405733_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007393 478.0
MMD2_k127_405733_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 374.0
MMD2_k127_405733_3 - - - - 0.000000000000000000000000000000001318 138.0
MMD2_k127_405733_4 Belongs to the UPF0434 family - - - 0.0000000000000000001085 89.0
MMD2_k127_4062831_0 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 2.515e-236 738.0
MMD2_k127_4062831_1 AMP-binding enzyme C-terminal domain K01912 - 6.2.1.30 7.187e-228 710.0
MMD2_k127_4062831_2 PFAM amino acid-binding ACT domain protein - - - 0.00000000000000000000000000000000000000000000000000000000004266 207.0
MMD2_k127_4062831_3 LysM domain - - - 0.000000000000000000000000000000000000000000000003723 186.0
MMD2_k127_4062831_4 LysM domain - - - 0.000000000000000000000000000000000000000007501 167.0
MMD2_k127_4110202_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 1.224e-231 724.0
MMD2_k127_4110202_1 - - - - 0.0000000000000000000000000000000000000000000000000000001141 199.0
MMD2_k127_4110202_2 Stage II sporulation protein M K06384 - - 0.0000000000000000000000000000000000000000007 161.0
MMD2_k127_4110202_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0034641,GO:0043170,GO:0043737,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.7 0.00000000000000000000001446 105.0
MMD2_k127_411366_0 methanogenesis marker protein 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 429.0
MMD2_k127_411366_1 homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 322.0
MMD2_k127_411366_2 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 335.0
MMD2_k127_411366_3 PFAM response regulator receiveR - - - 0.0000000000000000000000000000000000000000000000000000006132 198.0
MMD2_k127_411366_4 PP-loop domain protein K06864 - - 0.0000000000000000000000000138 112.0
MMD2_k127_4121424_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000005412 281.0
MMD2_k127_4121424_1 FHA domain containing protein - - - 0.0000000000000000000000000000000000000000000000000008346 194.0
MMD2_k127_4121424_2 Alpha Beta K06889 - - 0.0000000000000000000000000000000000000006013 154.0
MMD2_k127_4121424_3 Subtilase family - - - 0.0002259 53.0
MMD2_k127_4154634_0 self proteolysis - - - 0.00000007387 59.0
MMD2_k127_4172248_0 COG2217 Cation transport ATPase K01533 - 3.6.3.4 3.02e-277 869.0
MMD2_k127_4172248_1 - - - - 0.000000000005866 69.0
MMD2_k127_4179923_0 phosphohydrolase (DHH superfamily) K07097 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 366.0
MMD2_k127_4179923_1 - - - - 0.000000000000000000000000000000000000000000000000209 185.0
MMD2_k127_4179923_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000573 108.0
MMD2_k127_4196067_0 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005415 267.0
MMD2_k127_4196067_1 NMT1/THI5 like - - - 0.00001663 51.0
MMD2_k127_4196067_2 Flavin reductase like domain - - - 0.0001697 46.0
MMD2_k127_421211_0 Catalyzes the attachment of O-phosphoserine (Sep) to tRNA(Cys) K07587 - 6.1.1.27 4.568e-253 790.0
MMD2_k127_421211_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 417.0
MMD2_k127_421211_2 NTPase - - - 0.0001134 46.0
MMD2_k127_4217486_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 4.322e-218 687.0
MMD2_k127_4217486_1 PFAM Radical SAM domain protein K07129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007498 404.0
MMD2_k127_4217486_2 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 394.0
MMD2_k127_4217486_3 PFAM GTP-binding protein HSR1-related K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005107 366.0
MMD2_k127_4217486_4 PFAM CBS domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002539 270.0
MMD2_k127_4217486_5 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007265 246.0
MMD2_k127_4217486_6 Uncharacterized protein conserved in archaea (DUF2073) K09743 - - 0.00000000000000000000000000000000000000000000000001382 181.0
MMD2_k127_4217486_7 Zn-ribbon containing protein K07163 - - 0.0000000000000000000000000000000000000000000000001409 179.0
MMD2_k127_4217486_8 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 - 2.5.1.89 0.000000000000000000006776 95.0
MMD2_k127_4236622_0 PFAM ferredoxin-dependent glutamate synthase - - - 1.547e-288 891.0
MMD2_k127_4236622_1 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 418.0
MMD2_k127_4236622_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008509 270.0
MMD2_k127_4236622_3 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000004045 124.0
MMD2_k127_4236622_4 TIR domain - - - 0.000000000000001217 85.0
MMD2_k127_4274189_0 PFAM SufBD protein K07033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 574.0
MMD2_k127_4274189_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 290.0
MMD2_k127_4274189_2 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001155 280.0
MMD2_k127_4274189_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005444 278.0
MMD2_k127_4274189_4 PFAM cyclase family protein K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000009981 176.0
MMD2_k127_4274189_5 - - - - 0.000000000000000000000000000000000000000003177 162.0
MMD2_k127_4292891_0 Pyridine nucleotide-disulphide oxidoreductase K00529,K18227,K18249 - 1.18.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000001574 251.0
MMD2_k127_4292891_1 Predicted membrane protein (DUF2231) - - - 0.000000000000000002803 91.0
MMD2_k127_4310637_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 7.746e-199 622.0
MMD2_k127_4310637_1 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 352.0
MMD2_k127_4310637_2 SMART phosphoesterase PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 292.0
MMD2_k127_4310637_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000000000000000001001 111.0
MMD2_k127_4310637_4 RNA-binding protein involved in rRNA processing K07569 - - 0.00000000000000000001554 95.0
MMD2_k127_4329993_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 614.0
MMD2_k127_4329993_1 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000000002493 108.0
MMD2_k127_4329993_2 CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette - - - 0.0000007176 53.0
MMD2_k127_4352966_0 Ferrous iron transport B domain protein K04759 - - 4.484e-211 675.0
MMD2_k127_4352966_1 Helix-hairpin-helix domain K02347 - - 8.21e-196 625.0
MMD2_k127_4352966_2 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006766 302.0
MMD2_k127_4352966_3 PFAM conserved K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 294.0
MMD2_k127_4352966_4 PFAM Di-trans-poly-cis-decaprenylcistransferase K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000001735 237.0
MMD2_k127_4352966_5 Mn-dependent transcriptional regulator K03709 - - 0.000000000000000000000000000000000000007722 154.0
MMD2_k127_4352966_6 Protein of unknown function (DUF357) K09728 - - 0.00000000000000000000000000001168 128.0
MMD2_k127_4360241_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 474.0
MMD2_k127_4360241_1 Beta-eliminating lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 370.0
MMD2_k127_4360241_2 Spore coat polysaccharide biosynthesis protein F, CMP-KDO synthetase - - - 0.00001574 54.0
MMD2_k127_4362756_0 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008471 337.0
MMD2_k127_4362756_1 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000005904 249.0
MMD2_k127_4362756_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000285 235.0
MMD2_k127_4362756_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000003774 233.0
MMD2_k127_437484_0 Conserved region in glutamate synthase - - - 1.492e-215 672.0
MMD2_k127_437484_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000009552 232.0
MMD2_k127_437484_2 TIR domain - - - 0.0000000009469 65.0
MMD2_k127_4375107_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 2.98e-225 705.0
MMD2_k127_4375107_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000005292 222.0
MMD2_k127_4375107_2 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000001864 94.0
MMD2_k127_4375107_3 Protein of unknown function (DUF2953) - - - 0.0000000000000003079 86.0
MMD2_k127_4408402_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1269.0
MMD2_k127_4408402_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1075.0
MMD2_k127_4408402_2 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 319.0
MMD2_k127_4408402_3 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K02006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 304.0
MMD2_k127_4408402_4 - - - - 0.00000000000000000000000000000000000000001155 156.0
MMD2_k127_4408402_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000001154 109.0
MMD2_k127_4408402_6 Tetratricopeptide repeat - - - 0.000000000000000004328 91.0
MMD2_k127_4434512_0 TIGRFAM AAA family ATPase, CDC48 subfamily K13525 - - 0.0 1065.0
MMD2_k127_4434512_1 PFAM ABC transporter K00400 - - 5.452e-274 850.0
MMD2_k127_4434512_2 Belongs to the UPF0288 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 540.0
MMD2_k127_4434512_3 Belongs to the eIF-2B alpha beta delta subunits family K18237 - 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 404.0
MMD2_k127_4434512_4 Belongs to the LarC family K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 403.0
MMD2_k127_4434512_5 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 370.0
MMD2_k127_4434512_6 PFAM Haloacid dehalogenase domain protein hydrolase K17686 - 3.6.3.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 332.0
MMD2_k127_4434512_7 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002452 274.0
MMD2_k127_4434512_8 Uncharacterized protein conserved in archaea (DUF2102) - - - 0.000000000000000000000000000000000000000000000000008207 188.0
MMD2_k127_4437112_0 acid binding OB-fold tRNA helicase-type K07463 - - 2.168e-294 916.0
MMD2_k127_4437112_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000223 410.0
MMD2_k127_4437112_2 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000001679 243.0
MMD2_k127_4437112_3 adenyl ribonucleotide binding - - - 0.00000000000000000000000000000000000000000000000000000008506 200.0
MMD2_k127_4437112_4 - - - - 0.000000000000000000000000000000007445 129.0
MMD2_k127_4437112_5 - - - - 0.000000000000003305 82.0
MMD2_k127_4452047_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1216.0
MMD2_k127_4452047_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.0 1054.0
MMD2_k127_4452047_2 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 1.635e-298 922.0
MMD2_k127_4452047_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 1.772e-194 614.0
MMD2_k127_4452047_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 346.0
MMD2_k127_4452047_5 transcription termination protein NusA K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000472 216.0
MMD2_k127_4452047_6 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.000000000000000000000000000004634 121.0
MMD2_k127_4452047_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000000000002271 118.0
MMD2_k127_4452047_8 PFAM Ribonuclease III K03685 - 3.1.26.3 0.00000000000000000000000000004037 120.0
MMD2_k127_4452047_9 Phosphate-starvation-inducible E - - - 0.000000000000000000000002649 107.0
MMD2_k127_446602_0 PFAM Thiolase K00626 - 2.3.1.9 1.335e-206 648.0
MMD2_k127_446602_1 Methyltransferase K15429 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 373.0
MMD2_k127_446602_2 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
MMD2_k127_446602_3 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000004192 75.0
MMD2_k127_446602_4 Belongs to the HMG-CoA reductase family K00021 - 1.1.1.34 0.00000000005829 66.0
MMD2_k127_4482479_0 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008721 458.0
MMD2_k127_4482479_1 Cation transporter/ATPase, N-terminus - - - 0.00000000000000000000000000000000000000146 152.0
MMD2_k127_448993_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 5.078e-254 792.0
MMD2_k127_448993_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 487.0
MMD2_k127_448993_2 Catalyzes the reversible reduction of methenyl- H(4)MPT( ) to methylene-H(4)MPT K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 467.0
MMD2_k127_448993_3 Putative RNA methyltransferase K09142 - - 0.000000000000000000000000000000000000000000000000000000000000001297 228.0
MMD2_k127_448993_4 PFAM sigma-70 region 4 domain protein K09714 - - 0.0000000000000000000000000000000000000000000000000004211 187.0
MMD2_k127_448993_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000003739 121.0
MMD2_k127_4494713_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008881 447.0
MMD2_k127_4494713_1 PFAM Methyltransferase type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 415.0
MMD2_k127_4494713_10 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000001995 58.0
MMD2_k127_4494713_11 - - - - 0.00001218 54.0
MMD2_k127_4494713_2 PFAM ABC transporter related K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 389.0
MMD2_k127_4494713_3 Mitochondrial biogenesis AIM24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 330.0
MMD2_k127_4494713_4 PFAM ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002844 327.0
MMD2_k127_4494713_5 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000001178 164.0
MMD2_k127_4494713_6 Belongs to the UPF0216 family K09737 - - 0.0000000000000000000000000000000000003485 144.0
MMD2_k127_4494713_7 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000005892 146.0
MMD2_k127_4494713_8 - K00960 - 2.7.7.6 0.000000000000000000000000000007737 118.0
MMD2_k127_4494713_9 - K00960 - 2.7.7.6 0.00000000000000000000000343 106.0
MMD2_k127_4498324_0 ATP-grasp domain K06914 - 6.3.4.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 391.0
MMD2_k127_4498324_1 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.0000000000000000000000000000000000000000000003654 171.0
MMD2_k127_4498324_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000002704 126.0
MMD2_k127_4517840_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 515.0
MMD2_k127_4517840_1 PFAM ribonuclease II K01147 - 3.1.13.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 489.0
MMD2_k127_4517840_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001673 267.0
MMD2_k127_4518163_0 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 324.0
MMD2_k127_4518163_1 protein with SCP PR1 domains - - - 0.0000000000957 73.0
MMD2_k127_4518163_2 PFAM SCP-like extracellular - - - 0.000009275 52.0
MMD2_k127_4518163_3 PFAM Cysteine-rich secretory protein family - - - 0.0001145 48.0
MMD2_k127_4527755_0 PFAM peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 531.0
MMD2_k127_4527755_1 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 490.0
MMD2_k127_4527755_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008902 381.0
MMD2_k127_4527755_3 TIGRFAM cell division ATPase MinD K03609 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 308.0
MMD2_k127_4527755_4 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005795 275.0
MMD2_k127_4527755_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000001513 250.0
MMD2_k127_4527755_6 NfeD-like C-terminal, partner-binding - - - 0.0000000000000000000000000000000000000000000000000005773 187.0
MMD2_k127_4527755_7 tetratricopeptide repeat - - - 0.000000000000003184 84.0
MMD2_k127_4527755_8 COG1413 FOG HEAT repeat - - - 0.000000000006591 74.0
MMD2_k127_4527755_9 - - - - 0.00000005062 56.0
MMD2_k127_4539939_0 PFAM amine oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 486.0
MMD2_k127_4539939_1 Involved in cell shape control K22222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 366.0
MMD2_k127_4539939_2 PFAM Glycosyl transferase family 2 K07027 - - 0.00000000000000000000006442 104.0
MMD2_k127_4574614_0 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 316.0
MMD2_k127_4574614_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 312.0
MMD2_k127_4574614_2 PFAM peptidase zinc-dependent K06974 - - 0.00000000000000000000000000000000000000000000000000000000003193 211.0
MMD2_k127_4574614_3 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K01823,K06989 - 1.4.1.21,5.3.3.2 0.000000000000000000000000000000000000000000002062 165.0
MMD2_k127_4574614_4 Belongs to the UPF0146 family K09713 - - 0.00000000000000000000000000000000000000216 150.0
MMD2_k127_4574614_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000000000000005382 111.0
MMD2_k127_4607707_0 PFAM ABC-1 domain protein K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 595.0
MMD2_k127_4607707_1 Catalyzes the radical-mediated transfer of the hydroxybenzyl group from 4-hydroxyphenylpyruvate (HPP) to 5-amino- 6-ribitylamino-2,4(1H,3H)-pyrimidinedione to form 7,8-didemethyl- 8-hydroxy-5-deazariboflavin (FO) K11780 - 2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 443.0
MMD2_k127_4607707_10 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000008292 141.0
MMD2_k127_4607707_11 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.000000000000000000000000000006914 127.0
MMD2_k127_4607707_12 PFAM dihydropteroate synthase, DHPS K00796 - 2.5.1.15 0.00000000000000000000000002129 110.0
MMD2_k127_4607707_13 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000005707 102.0
MMD2_k127_4607707_2 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 388.0
MMD2_k127_4607707_3 PFAM major facilitator superfamily MFS_1 K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 389.0
MMD2_k127_4607707_4 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 335.0
MMD2_k127_4607707_5 TIGRFAM F420-dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 331.0
MMD2_k127_4607707_6 Phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 286.0
MMD2_k127_4607707_7 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001566 272.0
MMD2_k127_4607707_8 methyltransferase small K07579 - - 0.00000000000000000000000000000000000000000000000000000000000000000007639 237.0
MMD2_k127_4607707_9 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000000000000000001592 184.0
MMD2_k127_4611606_0 type II secretion system protein K07333 - - 1.281e-214 678.0
MMD2_k127_4611606_1 PFAM type II secretion system protein E K07332 - - 0.0000000000000006238 77.0
MMD2_k127_4630557_0 peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 445.0
MMD2_k127_4630557_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 430.0
MMD2_k127_4630557_2 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 373.0
MMD2_k127_4630557_3 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000000000003412 238.0
MMD2_k127_4630557_4 - - - - 0.000000000000000000000000000000000000000000000000000002718 196.0
MMD2_k127_4630557_5 involved in cell wall biogenesis K00721 - 2.4.1.83 0.00000000000000000000000000000000000008123 151.0
MMD2_k127_4630557_6 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000003174 126.0
MMD2_k127_4630557_7 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.00000000000000000000009101 102.0
MMD2_k127_4630557_8 lysyltransferase activity K07027 - - 0.000005911 58.0
MMD2_k127_4645054_0 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 402.0
MMD2_k127_4645054_1 PFAM NAD(P)H dehydrogenase (quinone) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 351.0
MMD2_k127_4645054_2 TIGRFAM PAS sensor protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 337.0
MMD2_k127_4645054_3 SpoIIAA-like - - - 0.000000000000000000000000000003096 122.0
MMD2_k127_4645054_4 - - - - 0.00000000002683 67.0
MMD2_k127_4645054_5 TfoX N-terminal domain - - - 0.0000000001188 67.0
MMD2_k127_4646845_0 F420-non-reducing hydrogenase subunit G K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 510.0
MMD2_k127_4646845_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006469 403.0
MMD2_k127_4646845_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000944 269.0
MMD2_k127_4646845_3 Peptidase A24A, prepilin type IV K07991 - 3.4.23.52 0.000000000000000000000000000000000000000000000000000000000000000001041 241.0
MMD2_k127_4646845_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000003124 141.0
MMD2_k127_4649243_0 Protein-export membrane protein SecD K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008871 493.0
MMD2_k127_4649243_1 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 443.0
MMD2_k127_4649243_10 PFAM ABC transporter K16786 - - 0.00000000000000000000000001778 112.0
MMD2_k127_4649243_11 - - - - 0.000000000000000002329 89.0
MMD2_k127_4649243_2 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 374.0
MMD2_k127_4649243_3 Involved in protein export K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 331.0
MMD2_k127_4649243_4 Belongs to the RtcB family K14415 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 307.0
MMD2_k127_4649243_5 Uncharacterized protein conserved in archaea (DUF2111) - - - 0.0000000000000000000000000000000000000000000000000000000003917 205.0
MMD2_k127_4649243_6 - - - - 0.0000000000000000000000000000000000000000000000000000002662 208.0
MMD2_k127_4649243_7 PFAM BioY protein K03523 - - 0.000000000000000000000000000000000000000000000000002942 187.0
MMD2_k127_4649243_8 Protein of unknown function (DUF2551) - - - 0.0000000000000000000000000000000000006044 141.0
MMD2_k127_4649243_9 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000000001342 128.0
MMD2_k127_4658258_0 HI0933 family K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 438.0
MMD2_k127_4658258_1 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009593 361.0
MMD2_k127_4658258_11 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.0001516 48.0
MMD2_k127_4658258_12 - - - - 0.0004985 49.0
MMD2_k127_4658258_2 COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002047 335.0
MMD2_k127_4658258_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 324.0
MMD2_k127_4658258_4 PFAM Pyridoxamine 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000004915 196.0
MMD2_k127_4658258_6 Pas domain - - - 0.00000000000000000000000000000000000000000000007971 179.0
MMD2_k127_4658258_7 ChaB K06197 - - 0.0000000000000001782 83.0
MMD2_k127_4658258_8 PFAM Uncharacterised protein family (UPF0153) - - - 0.00000000000004255 78.0
MMD2_k127_4658258_9 - - - - 0.0000000000005914 74.0
MMD2_k127_4681673_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1130.0
MMD2_k127_4681673_1 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 304.0
MMD2_k127_4681673_2 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.000000000000000000000000000000000000000000000000000000000000203 215.0
MMD2_k127_4684375_0 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 379.0
MMD2_k127_4684375_1 Belongs to the archaeal adenylate kinase family K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004814 271.0
MMD2_k127_4684375_2 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000000001163 228.0
MMD2_k127_4684375_3 Integral membrane protein DUF106 - - - 0.000000000000000000000000000000000000000000000000000000000000000002647 233.0
MMD2_k127_4684375_4 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000000000000000000001245 196.0
MMD2_k127_4691858_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1236.0
MMD2_k127_4691858_1 PFAM CBS domain - - - 2.389e-232 728.0
MMD2_k127_4691858_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 376.0
MMD2_k127_4691858_3 NIF3 (NGG1p interacting factor 3) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006178 280.0
MMD2_k127_4691858_4 Belongs to the UPF0280 family K09740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001642 278.0
MMD2_k127_4691858_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000009344 178.0
MMD2_k127_4691858_6 Helix-turn-helix domain - - - 0.00000000000000000000000000000000412 138.0
MMD2_k127_4691858_7 zinc finger, SWIM - - - 0.0000000000000000000000000002708 120.0
MMD2_k127_4691858_8 - - - - 0.000000000000000001483 88.0
MMD2_k127_4710805_0 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing growth on acetate as sole source of carbon and energy. The alpha-epsilon complex generates CO from CO(2), while the beta subunit (this protein) combines the CO with CoA and a methyl group to form acetyl-CoA. The methyl group, which is incorporated into acetyl-CoA, is transferred to the beta subunit by a corrinoid iron-sulfur protein (the gamma-delta complex) K00193 - - 3.662e-304 945.0
MMD2_k127_4710805_1 2Fe-2S iron-sulfur cluster binding domain - - - 3.594e-198 627.0
MMD2_k127_4710805_2 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003177 548.0
MMD2_k127_4710805_3 Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009992 378.0
MMD2_k127_4710805_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000001375 180.0
MMD2_k127_4710805_5 Protein of unknown function (DUF2769) - - - 0.000000000000000000000000000000002146 132.0
MMD2_k127_4710805_6 Transcriptional regulator K07729 - - 0.0000000000000000000001536 102.0
MMD2_k127_4710805_7 Protein of unknown function (DUF3147) - - - 0.00000000000000000002077 95.0
MMD2_k127_4710805_8 - - - - 0.000000000000000002654 89.0
MMD2_k127_4728590_0 PFAM Ion transport protein K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 294.0
MMD2_k127_4728590_1 PFAM TM2 domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001007 286.0
MMD2_k127_4728590_2 PFAM TM2 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000005579 214.0
MMD2_k127_4728590_3 PFAM PEGA domain - - - 0.00000000000000000000000000000000000000000000000000000001465 214.0
MMD2_k127_4740332_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000596 545.0
MMD2_k127_4740332_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 301.0
MMD2_k127_4740332_2 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000001908 233.0
MMD2_k127_4740332_3 Helix-turn-helix domain protein K03627 - - 0.00000000000000000000000000000000000000000000001122 179.0
MMD2_k127_4744241_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 499.0
MMD2_k127_4744241_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 421.0
MMD2_k127_4744241_2 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 368.0
MMD2_k127_4760189_0 Heat shock 70 kDa protein K04043 - - 1.072e-232 728.0
MMD2_k127_4760189_1 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 7.143e-209 659.0
MMD2_k127_4760189_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 585.0
MMD2_k127_4760189_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005902 385.0
MMD2_k127_4760189_4 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000001684 267.0
MMD2_k127_4760189_5 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000000000000002357 224.0
MMD2_k127_4760189_6 Protein of unknown function (DUF4013) - - - 0.000000000000000000000000000000000000000000000000000000002411 207.0
MMD2_k127_4760189_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000002503 126.0
MMD2_k127_4760189_8 Protein of unknown function (DUF4013) - - - 0.00000000000000000000000000001132 126.0
MMD2_k127_4771110_0 amino acid K03294 - - 1.758e-268 841.0
MMD2_k127_477126_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 296.0
MMD2_k127_477126_1 TPR repeat - - - 0.000000000000000000001282 97.0
MMD2_k127_4773092_0 pfam nmd3 K07562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004135 310.0
MMD2_k127_4773092_1 PFAM TatD-related deoxyribonuclease K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001129 245.0
MMD2_k127_4773092_2 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000000000000116 116.0
MMD2_k127_4799294_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K00342,K05568 - 1.6.5.3 0.0 1284.0
MMD2_k127_4799294_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter MnhD subunit K00343,K05568,K14115,K22169 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000001028 217.0
MMD2_k127_4817013_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.998e-289 898.0
MMD2_k127_4817013_1 Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 574.0
MMD2_k127_4817013_2 UDP-glucose:hexose-1-phosphate uridylyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 336.0
MMD2_k127_4833215_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.451e-306 949.0
MMD2_k127_4833215_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 587.0
MMD2_k127_4833215_10 - - - - 0.00000000000000000000000000005739 123.0
MMD2_k127_4833215_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 481.0
MMD2_k127_4833215_3 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 403.0
MMD2_k127_4833215_4 PFAM ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 369.0
MMD2_k127_4833215_5 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 298.0
MMD2_k127_4833215_6 - - - - 0.000000000000000000000000000000000000000000000000000000000007138 211.0
MMD2_k127_4833215_7 N-6 DNA Methylase - - - 0.00000000000000000000000000000000000000000000000000000000001369 231.0
MMD2_k127_4833215_8 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000002202 186.0
MMD2_k127_4833215_9 PFAM transcriptional regulator PadR family protein - - - 0.000000000000000000000000000000000003279 143.0
MMD2_k127_4858768_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 378.0
MMD2_k127_4858768_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009445 342.0
MMD2_k127_4858768_2 PFAM multicopper oxidase K22348 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000001026 227.0
MMD2_k127_4858768_3 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000002528 181.0
MMD2_k127_4858768_4 antibiotic catabolic process K18235 - - 0.0000000000000000000000000001051 128.0
MMD2_k127_4873315_0 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 324.0
MMD2_k127_4873315_1 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000005372 66.0
MMD2_k127_4898474_0 Belongs to the RNA polymerase beta chain family K03045 - 2.7.7.6 1.807e-274 847.0
MMD2_k127_4898474_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 584.0
MMD2_k127_4930963_0 PFAM Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 572.0
MMD2_k127_4930963_1 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 559.0
MMD2_k127_4930963_10 - - - - 0.000000000000000000000000000000001773 129.0
MMD2_k127_4930963_11 helicase activity K06915 - - 0.00000000000000000000000000000009027 134.0
MMD2_k127_4930963_12 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.000000000000000000004727 94.0
MMD2_k127_4930963_13 TPR repeat-containing protein - - - 0.0000000000000000002618 93.0
MMD2_k127_4930963_14 - - - - 0.0000000000001236 80.0
MMD2_k127_4930963_15 TIGRFAM aspartate ammonia-lyase K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000002741 76.0
MMD2_k127_4930963_2 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 531.0
MMD2_k127_4930963_3 Catalyzes the condensation of 4-aminobenzoate (pABA) with 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to produce beta-ribofuranosylaminobenzene 5'-phosphate (beta-RFA-P) K06984 - 2.4.2.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 537.0
MMD2_k127_4930963_4 phosphoglycerate mutase K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 521.0
MMD2_k127_4930963_5 PFAM Radical SAM domain protein K02585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 478.0
MMD2_k127_4930963_6 Elongator protein 3, MiaB family, Radical SAM K06935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 440.0
MMD2_k127_4930963_7 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 403.0
MMD2_k127_4930963_8 His Kinase A (phospho-acceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007462 407.0
MMD2_k127_4930963_9 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006544 267.0
MMD2_k127_4935489_0 PFAM AIR synthase related protein K07123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002182 511.0
MMD2_k127_4935489_1 methanogen marker protein 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000009574 239.0
MMD2_k127_4935489_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000000000000000003025 172.0
MMD2_k127_4935489_3 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000003587 149.0
MMD2_k127_4949131_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 431.0
MMD2_k127_4949131_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 357.0
MMD2_k127_4949131_2 TIGRFAM signal peptide peptidase SppA, 36K type K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
MMD2_k127_4949131_3 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000419 240.0
MMD2_k127_4949131_4 hydrolase K04794 - 3.1.1.29 0.0000000000000000000000000000000000000000000005616 173.0
MMD2_k127_497523_0 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000006892 226.0
MMD2_k127_497523_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000719 183.0
MMD2_k127_497523_2 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000086 135.0
MMD2_k127_4976842_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.848e-235 735.0
MMD2_k127_4976842_1 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 380.0
MMD2_k127_4976842_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003274 284.0
MMD2_k127_4976842_3 PFAM regulatory protein, ArsR K07721 - - 0.00000000000000000000000000000000000000000000000000000000000001691 221.0
MMD2_k127_4976842_4 ABC-2 family transporter protein - - - 0.000000000000000000000000000000000000000000000003813 188.0
MMD2_k127_4976842_5 HxlR-like helix-turn-helix - - - 0.000000000000000000000000000000000000157 145.0
MMD2_k127_4976842_6 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000002862 139.0
MMD2_k127_4976842_7 HEAT repeats - - - 0.000000000000000000000000000000199 132.0
MMD2_k127_4976842_8 - - - - 0.0000007673 59.0
MMD2_k127_4979489_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000299 588.0
MMD2_k127_4979489_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 369.0
MMD2_k127_4979489_10 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000005503 219.0
MMD2_k127_4979489_11 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02930 - - 0.000000000000000000000000000000000000000000000000000000000000006042 220.0
MMD2_k127_4979489_12 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000001136 211.0
MMD2_k127_4979489_13 binds to the 23S rRNA K02885 - - 0.000000000000000000000000000000000000000000000000000000001665 204.0
MMD2_k127_4979489_14 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000000000004038 201.0
MMD2_k127_4979489_15 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000000000000000000000001938 186.0
MMD2_k127_4979489_16 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000003121 158.0
MMD2_k127_4979489_17 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 - - 0.0000000000000000000000000000000000002348 149.0
MMD2_k127_4979489_18 PFAM Ribosomal protein K02912 - - 0.0000000000000000000000000000000000003374 146.0
MMD2_k127_4979489_19 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.000000000000000000000000006074 112.0
MMD2_k127_4979489_2 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 349.0
MMD2_k127_4979489_20 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000000000000005397 101.0
MMD2_k127_4979489_21 Binds 16S rRNA, required for the assembly of 30S particles K02954 - - 0.000000000000000000003949 97.0
MMD2_k127_4979489_22 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000000003256 91.0
MMD2_k127_4979489_3 With S4 and S12 plays an important role in translational accuracy K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 338.0
MMD2_k127_4979489_4 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 309.0
MMD2_k127_4979489_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000002101 240.0
MMD2_k127_4979489_6 TIGRFAM ribosomal protein L30P K02907 - - 0.000000000000000000000000000000000000000000000000000000000000000000004102 243.0
MMD2_k127_4979489_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000000004103 235.0
MMD2_k127_4979489_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000586 229.0
MMD2_k127_4979489_9 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000000004652 226.0
MMD2_k127_498143_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 2.321e-199 629.0
MMD2_k127_498143_1 PFAM Methionine synthase, vitamin-B12 independent K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 355.0
MMD2_k127_498143_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000002418 198.0
MMD2_k127_498143_3 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000000000000000000000000000000000000000000003977 184.0
MMD2_k127_5008831_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.575e-258 808.0
MMD2_k127_5008831_1 transferase hexapeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001148 256.0
MMD2_k127_5008831_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000000000000000000000003928 230.0
MMD2_k127_5008831_3 transferase hexapeptide repeat containing protein K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000426 154.0
MMD2_k127_5021079_0 binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000001607 224.0
MMD2_k127_5021079_1 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000003145 167.0
MMD2_k127_5021079_2 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems, periplasmic components K02051 GO:0003674,GO:0005215 - 0.00002597 51.0
MMD2_k127_5048830_0 PFAM Aldehyde dehydrogenase K00130,K00135 - 1.2.1.16,1.2.1.20,1.2.1.79,1.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 532.0
MMD2_k127_5048830_1 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 373.0
MMD2_k127_5048830_2 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001143 273.0
MMD2_k127_5048830_3 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000000002283 187.0
MMD2_k127_5048830_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000002964 147.0
MMD2_k127_5048830_5 AN1-like Zinc finger - - - 0.00000005258 60.0
MMD2_k127_5050590_0 Pyridine nucleotide-disulphide oxidoreductase K00382,K00383 - 1.8.1.4,1.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 452.0
MMD2_k127_5050590_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 432.0
MMD2_k127_5050590_2 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 374.0
MMD2_k127_5050590_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 318.0
MMD2_k127_5050590_4 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000001896 158.0
MMD2_k127_5055693_0 PFAM Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000000000000000000000000000002797 217.0
MMD2_k127_5055693_1 PAS domain - - - 0.000000000000000000000000000000000000000000000000000000000003975 221.0
MMD2_k127_5055693_2 Diphthamide synthase K06927 - 6.3.1.14 0.0000000006455 60.0
MMD2_k127_5055700_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.245e-233 727.0
MMD2_k127_5055700_1 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 415.0
MMD2_k127_5055700_2 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000001527 195.0
MMD2_k127_5055700_3 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000008119 171.0
MMD2_k127_5055700_4 - - - - 0.00000000000000000000000000000002436 128.0
MMD2_k127_5066402_0 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008812 330.0
MMD2_k127_5066402_1 PFAM oxidoreductase nitrogenase, component 1 - - - 0.00000000000000000000000000000000000000000000008073 175.0
MMD2_k127_5070698_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 8.973e-230 725.0
MMD2_k127_5070698_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 - 6.1.1.20 5.216e-209 660.0
MMD2_k127_5070698_10 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 361.0
MMD2_k127_5070698_11 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 329.0
MMD2_k127_5070698_12 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 306.0
MMD2_k127_5070698_13 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001062 271.0
MMD2_k127_5070698_14 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002674 247.0
MMD2_k127_5070698_15 Eco57I restriction-modification methylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003728 271.0
MMD2_k127_5070698_16 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000002418 239.0
MMD2_k127_5070698_17 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K11260 - - 0.00000000000000000000000000000000000005706 143.0
MMD2_k127_5070698_18 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00001271 48.0
MMD2_k127_5070698_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 600.0
MMD2_k127_5070698_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 558.0
MMD2_k127_5070698_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00205 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 542.0
MMD2_k127_5070698_5 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 518.0
MMD2_k127_5070698_6 PFAM isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 468.0
MMD2_k127_5070698_7 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 433.0
MMD2_k127_5070698_8 Domain of unknown function (DUF1743) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005125 415.0
MMD2_k127_5070698_9 sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005464 373.0
MMD2_k127_5075148_0 Sigma factor PP2C-like phosphatases K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000469 184.0
MMD2_k127_5075148_1 Ras family K06945 - - 0.0000000000000000000000000000000000000305 149.0
MMD2_k127_5075148_2 - - - - 0.000000000000000000000000000005384 120.0
MMD2_k127_5075148_3 - - - - 0.0000000000000000006303 89.0
MMD2_k127_509270_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 434.0
MMD2_k127_509270_1 Belongs to the glutamate synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 346.0
MMD2_k127_509270_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000167 189.0
MMD2_k127_509270_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0009263 49.0
MMD2_k127_5105062_0 SMART Elongator protein 3 MiaB NifB K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 427.0
MMD2_k127_5105062_1 LOR SDH bifunctional enzyme conserved - - - 0.00000000000000000000000000000000000000000000000002345 179.0
MMD2_k127_5114725_0 PFAM Radical SAM domain protein K06937 - - 8.419e-235 733.0
MMD2_k127_5114725_1 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 387.0
MMD2_k127_5128286_0 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 2.978e-232 728.0
MMD2_k127_5128286_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 549.0
MMD2_k127_5128286_2 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 346.0
MMD2_k127_5128286_3 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 316.0
MMD2_k127_5128286_4 Belongs to the eukaryotic ribosomal protein eS1 family K02984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001649 258.0
MMD2_k127_5128286_5 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000551 247.0
MMD2_k127_5128286_6 ribosomal protein S15 K02956 - - 0.00000000000000000000000000000000000000000000000000000000000000691 219.0
MMD2_k127_5128286_7 - - - - 0.0000000002147 65.0
MMD2_k127_5147896_0 ATP-grasp domain K06913 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 349.0
MMD2_k127_5147896_1 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000008697 256.0
MMD2_k127_5147896_2 regulator of amino acid metabolism, contains ACT domain K07103 - - 0.0000000000000000000000000000000000000000000000000000000000000003212 224.0
MMD2_k127_5147896_3 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000000000000000000000000000007868 217.0
MMD2_k127_5147896_4 Metal dependent phosphohydrolases with conserved 'HD' motif. K06950 - - 0.0000000000000000000000000000000000003933 146.0
MMD2_k127_5147896_5 PAS domain - - - 0.0000000000000000000000000000000000195 150.0
MMD2_k127_5147896_6 PQ loop repeat K15383 - - 0.00000000000000000007041 93.0
MMD2_k127_5147896_7 - - - - 0.0000000000004551 72.0
MMD2_k127_5147896_8 Diguanylate cyclase - - - 0.000005741 58.0
MMD2_k127_5154432_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 7.744e-217 680.0
MMD2_k127_5154432_1 COG0433 Predicted ATPase K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 517.0
MMD2_k127_5154432_2 PFAM Coenzyme F420 hydrogenase dehydrogenase, beta subunit K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 462.0
MMD2_k127_5154432_3 NADH ubiquinone oxidoreductase 20 kDa subunit K00443 - 1.12.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 423.0
MMD2_k127_5154432_4 coenzyme F420-reducing hydrogenase, delta subunit K00442 - - 0.000000000000000000000000000000000000000000000001028 179.0
MMD2_k127_5154432_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00440 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.98.1 0.000000000000000000000000000000000000000000006952 163.0
MMD2_k127_5168437_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.823e-283 880.0
MMD2_k127_5168437_1 Belongs to the dCTP deaminase family K01494,K09887 - 3.5.4.13,3.5.4.30 0.000000000000000000000000000000000000000000000007854 172.0
MMD2_k127_51769_0 PFAM peptidase U32 K08303 - - 6.874e-210 681.0
MMD2_k127_51769_1 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000006976 194.0
MMD2_k127_51769_2 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.0000000000000000000000000000000000000004811 154.0
MMD2_k127_51769_3 PFAM Histone deacetylase - - - 0.000000000000000000000000000000004809 132.0
MMD2_k127_51769_4 - - - - 0.00000000000000000000000000005473 120.0
MMD2_k127_51769_5 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00000000000000001384 87.0
MMD2_k127_51769_6 DNA ligase K01971 - 6.5.1.1 0.0000001646 54.0
MMD2_k127_5178822_0 CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 537.0
MMD2_k127_5178822_1 PFAM formyl transferase domain protein K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002103 263.0
MMD2_k127_5178822_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002751 249.0
MMD2_k127_5178822_3 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000000000000000004757 211.0
MMD2_k127_5178822_4 Belongs to the PDCD5 family K06875 - - 0.000000000000000000000000000000000003375 139.0
MMD2_k127_5178822_5 Belongs to the eukaryotic ribosomal protein eL31 family K02910 - - 0.00000000000000000000000000000006093 126.0
MMD2_k127_5178822_6 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000003881 117.0
MMD2_k127_5178822_7 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000000000006164 104.0
MMD2_k127_5178822_8 CRS1_YhbY K07574 - - 0.000000000000000000009978 93.0
MMD2_k127_5178822_9 structural constituent of ribosome K02924 - - 0.000000000000000001184 86.0
MMD2_k127_5183822_0 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 432.0
MMD2_k127_5183822_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000000000000000000000000000000000000000000718 195.0
MMD2_k127_5183822_2 PFAM blue (type 1) copper domain protein - - - 0.000000000000000000000000000000003724 134.0
MMD2_k127_5192143_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 409.0
MMD2_k127_5192143_1 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 314.0
MMD2_k127_5192143_2 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000706 254.0
MMD2_k127_5192143_3 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000008919 104.0
MMD2_k127_5198900_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 5.218e-238 739.0
MMD2_k127_5198900_1 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003892 379.0
MMD2_k127_5198900_2 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 375.0
MMD2_k127_5198900_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000000000117 199.0
MMD2_k127_5198900_4 - - - - 0.000000000000000000000000000000002815 132.0
MMD2_k127_5203360_0 TIGRFAM small GTP-binding protein K06943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 417.0
MMD2_k127_5203360_1 SMART Peptidase A22, presenilin signal peptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 347.0
MMD2_k127_5203360_2 - - - - 0.00000000000000000000000000000000002056 138.0
MMD2_k127_5203360_3 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000007777 125.0
MMD2_k127_5203360_4 signal transduction protein with CBS domains K07744 - - 0.0000000000002244 70.0
MMD2_k127_520958_0 DEAD DEAH box helicase domain protein K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 615.0
MMD2_k127_520958_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 475.0
MMD2_k127_5224483_0 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 359.0
MMD2_k127_5224483_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001659 258.0
MMD2_k127_5224483_2 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000004911 192.0
MMD2_k127_5244228_0 TIGRFAM histone acetyltransferase, ELP3 family K07739 - 2.3.1.48 2.432e-223 702.0
MMD2_k127_5244228_1 PHP C-terminal domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 438.0
MMD2_k127_5244228_10 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000000000000000000000001809 168.0
MMD2_k127_5244228_11 protein conserved in archaea K09723 - - 0.0000000000000000000000000000000000000002308 160.0
MMD2_k127_5244228_12 metal-binding protein - - - 0.00000000000000000000000006134 110.0
MMD2_k127_5244228_13 PFAM Ribosomal protein S27E K02978 - - 0.00000000000000000000001162 104.0
MMD2_k127_5244228_14 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000003872 97.0
MMD2_k127_5244228_15 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000008204 57.0
MMD2_k127_5244228_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 429.0
MMD2_k127_5244228_3 Translation initiation factor 2 alpha subunit K03237 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 368.0
MMD2_k127_5244228_4 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 311.0
MMD2_k127_5244228_5 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000005023 244.0
MMD2_k127_5244228_6 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.00000000000000000000000000000000000000000000000000000000000000000005529 233.0
MMD2_k127_5244228_7 Belongs to the UPF0179 family K09730 - - 0.00000000000000000000000000000000000000000000000000000000009215 213.0
MMD2_k127_5244228_8 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.000000000000000000000000000000000000000000000000000000008441 201.0
MMD2_k127_5244228_9 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000000000000001227 199.0
MMD2_k127_5253088_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000009794 196.0
MMD2_k127_5257536_0 N-formylglutamate amidohydrolase K01479 - 3.5.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 304.0
MMD2_k127_5257536_1 Restriction endonuclease K07448 - - 0.000000499 52.0
MMD2_k127_5260995_0 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 496.0
MMD2_k127_5260995_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 464.0
MMD2_k127_5260995_2 - - - - 0.000000000000000000000000000000001044 139.0
MMD2_k127_5260995_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000003926 98.0
MMD2_k127_5280658_0 Belongs to the MCM family K10726 - - 1.013e-300 936.0
MMD2_k127_5280658_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 478.0
MMD2_k127_5280658_2 protein conserved in archaea K09746 - - 0.000000000000000000811 94.0
MMD2_k127_5301007_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 5.762e-237 743.0
MMD2_k127_5301007_1 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 407.0
MMD2_k127_5301007_10 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.000000000000000001136 85.0
MMD2_k127_5301007_11 PFAM helix-turn-helix domain protein K07729 - - 0.0000000000000001366 85.0
MMD2_k127_5301007_12 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000006696 78.0
MMD2_k127_5301007_2 Domain of unknown function (DUF1917) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 309.0
MMD2_k127_5301007_3 TIGRFAM DNA-directed RNA polymerase K03049 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 296.0
MMD2_k127_5301007_4 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003146 246.0
MMD2_k127_5301007_5 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000001603 240.0
MMD2_k127_5301007_6 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000000000000000000000000000000000003702 205.0
MMD2_k127_5301007_7 Large family of predicted nucleotide-binding domains K07158 - - 0.0000000000000000000000000000005599 127.0
MMD2_k127_5301007_8 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000000000000000000000256 115.0
MMD2_k127_5301007_9 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000000183 99.0
MMD2_k127_5318422_0 AIR synthase related protein domain protein K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 436.0
MMD2_k127_5318422_1 Thiamine-phosphate synthase K21220 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000004608 244.0
MMD2_k127_5318422_2 Molybdopterin converting factor K03635 - 2.8.1.12 0.00000000000000000000000000000001096 130.0
MMD2_k127_5319198_0 PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000004388 204.0
MMD2_k127_5319198_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000001048 196.0
MMD2_k127_5319198_2 RibD C-terminal domain K14654 - 1.1.1.302 0.0000000000000000000000000000000000000000000000000006972 192.0
MMD2_k127_5320375_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1706.0
MMD2_k127_5320375_1 Carbamoyl-phosphate synthase, small chain K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 507.0
MMD2_k127_5320375_2 PFAM carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000003549 267.0
MMD2_k127_5320375_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000013 221.0
MMD2_k127_5320375_4 - - - - 0.000000000000000000000000000000001835 136.0
MMD2_k127_532426_0 sulfate reduction K00390 - 1.8.4.10,1.8.4.8 2.598e-205 644.0
MMD2_k127_532426_1 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 552.0
MMD2_k127_532426_10 deoxyribonuclease IV (phage-T4-induced) activity - - - 0.00000000000000000000376 106.0
MMD2_k127_532426_11 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins K00657 GO:0000287,GO:0003674,GO:0003824,GO:0004145,GO:0005488,GO:0006576,GO:0006595,GO:0006598,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034641,GO:0042402,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0046872,GO:0071704,GO:1901564,GO:1901565,GO:1901575 2.3.1.57 0.0000000000005085 81.0
MMD2_k127_532426_2 PFAM N-acetylneuraminic acid synthase K01654,K15898 - 2.5.1.56,2.5.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 450.0
MMD2_k127_532426_3 Beta-eliminating lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 332.0
MMD2_k127_532426_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003506 282.0
MMD2_k127_532426_5 Formyl transferase K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004204 269.0
MMD2_k127_532426_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000001163 227.0
MMD2_k127_532426_7 Aminotransferase class-III K01845,K07257,K21585 - 2.6.1.111,5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000003288 227.0
MMD2_k127_532426_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000007469 196.0
MMD2_k127_532426_9 Male sterility protein K01710 - 4.2.1.46 0.000000000000000000000000000000007673 128.0
MMD2_k127_5336812_0 aromatic amino acid beta-eliminating lyase threonine aldolase K11717 - 2.8.1.7,4.4.1.16 0.0 1158.0
MMD2_k127_5336812_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003748 547.0
MMD2_k127_5336812_2 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 359.0
MMD2_k127_5336812_3 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 338.0
MMD2_k127_5336812_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 304.0
MMD2_k127_5336812_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003918 280.0
MMD2_k127_5336812_6 Ferredoxin K05337 - - 0.000000000000000000000000001378 114.0
MMD2_k127_5336812_7 peptidase M42 family protein - - - 0.0000000000000000007393 86.0
MMD2_k127_5336812_8 Archaeal Type IV pilin, N-terminal - - - 0.000000000000005373 87.0
MMD2_k127_5336863_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.695e-228 715.0
MMD2_k127_5336863_1 Catalyzes the formation of 4-(hydroxymethyl)-2- furancarboxaldehyde phosphate (4-HFC-P) from two molecules of glyceraldehyde-3-P (GA-3-P) K09733 - 4.2.3.153 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 306.0
MMD2_k127_5336863_2 PFAM thymidylate kinase K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000004541 258.0
MMD2_k127_5336863_3 MafB19-like deaminase K01485 - 3.5.4.1 0.000000000000000000000000000000000000000000000000000000000000000000004223 236.0
MMD2_k127_5336863_4 Belongs to the HisA HisF family K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000006363 224.0
MMD2_k127_5336863_5 membrane - - - 0.00000000000000000000000000000000000000000000000000006869 191.0
MMD2_k127_5336863_6 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000000000000000000000000000000000006121 193.0
MMD2_k127_5336863_7 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000000005076 156.0
MMD2_k127_5336863_8 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000032 83.0
MMD2_k127_5344143_0 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 593.0
MMD2_k127_5344143_1 Belongs to the carbohydrate kinase PfkB family K00852,K22026 - 2.7.1.15,2.7.1.213,2.7.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 394.0
MMD2_k127_5344143_2 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003302 246.0
MMD2_k127_5344143_3 Belongs to the UPF0212 family K09731 - - 0.000000000000000000000000000000000000000000000005021 173.0
MMD2_k127_5374148_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 8.152e-281 880.0
MMD2_k127_5374148_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007919 514.0
MMD2_k127_5374148_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 469.0
MMD2_k127_5374148_3 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006123 300.0
MMD2_k127_5374148_4 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000000000000000000000009125 229.0
MMD2_k127_5374148_5 TIGRFAM molybdenum cofactor synthesis domain K03638 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000003272 203.0
MMD2_k127_5374148_6 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000000000000000000000000000001455 149.0
MMD2_k127_5374173_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 5.177e-262 822.0
MMD2_k127_5374173_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 567.0
MMD2_k127_5374173_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 523.0
MMD2_k127_5374173_3 PFAM NAD dependent epimerase dehydratase family K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 395.0
MMD2_k127_5374173_4 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 300.0
MMD2_k127_5374173_5 cytidyltransferase-related domain K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001962 276.0
MMD2_k127_5374173_6 PFAM transferase hexapeptide repeat containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008086 265.0
MMD2_k127_5374173_7 PFAM NAD-dependent epimerase dehydratase K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000001167 177.0
MMD2_k127_5374173_8 Group 1 family - - - 0.00000000000000000000000000000000000000006786 162.0
MMD2_k127_5374173_9 - - - - 0.00000000000000000000000001813 111.0
MMD2_k127_5397044_0 Anion transporter K14445 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 579.0
MMD2_k127_5397044_1 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 569.0
MMD2_k127_5397044_10 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000000000000000000000000000000000009957 222.0
MMD2_k127_5397044_11 aspartate glutamate uridylate kinase K07144 - 2.7.4.31 0.0000000000000000000000000000000000000000000000000001894 192.0
MMD2_k127_5397044_12 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000001033 167.0
MMD2_k127_5397044_14 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000002517 168.0
MMD2_k127_5397044_15 protein conserved in archaea - - - 0.00000000000000000000000000001721 121.0
MMD2_k127_5397044_16 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000000000000000002353 109.0
MMD2_k127_5397044_17 nucleic acid binding OB-fold tRNA helicase-type - - - 0.0000000000000000000000003552 113.0
MMD2_k127_5397044_18 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000000000003135 95.0
MMD2_k127_5397044_19 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000000000001281 89.0
MMD2_k127_5397044_2 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 550.0
MMD2_k127_5397044_3 Belongs to the LDH MDH superfamily K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 460.0
MMD2_k127_5397044_4 PFAM peptidase M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 404.0
MMD2_k127_5397044_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004323 378.0
MMD2_k127_5397044_6 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 377.0
MMD2_k127_5397044_7 nucleoside 2-deoxyribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 310.0
MMD2_k127_5397044_8 PFAM beta-lactamase domain protein K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 299.0
MMD2_k127_5397044_9 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 288.0
MMD2_k127_5419191_0 ATPases associated with a variety of cellular activities K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009128 341.0
MMD2_k127_5419191_1 ABC-type molybdate transport system periplasmic component K15495 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 293.0
MMD2_k127_5419191_2 ABC-type tungstate transport system, periplasmic component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002887 267.0
MMD2_k127_5435152_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 400.0
MMD2_k127_5435152_1 PFAM bifunctional deaminase-reductase domain protein K14654 - 1.1.1.302 0.000000000000000000000000000000000000000000001608 166.0
MMD2_k127_5435152_2 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000000000001627 149.0
MMD2_k127_5435152_3 PBS lyase HEAT-like repeat - - - 0.0000000000000005669 83.0
MMD2_k127_5477651_0 Protein of unknown function (DUF460) K09150 - - 2.026e-234 751.0
MMD2_k127_5477651_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 3.537e-199 622.0
MMD2_k127_5477651_10 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.00000000000000000000000002206 113.0
MMD2_k127_5477651_11 RNA-binding protein involved in rRNA processing K07569 - - 0.000000000000000000002766 96.0
MMD2_k127_5477651_12 - - - - 0.00000000000001008 75.0
MMD2_k127_5477651_13 PFAM PP-loop domain protein - - - 0.00000000000003519 74.0
MMD2_k127_5477651_2 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 353.0
MMD2_k127_5477651_3 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 350.0
MMD2_k127_5477651_4 Rio2, N-terminal K07179 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 337.0
MMD2_k127_5477651_5 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009204 282.0
MMD2_k127_5477651_6 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.000000000000000000000000000000000000000000001396 173.0
MMD2_k127_5477651_7 PFAM ribosomal protein S8E K02995 - - 0.000000000000000000000000000000000000000000003853 169.0
MMD2_k127_5477651_8 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000002478 154.0
MMD2_k127_5477651_9 - - - - 0.00000000000000000000000000000000000008784 147.0
MMD2_k127_5498254_0 PFAM Beta propeller domain K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 527.0
MMD2_k127_5498254_1 PFAM Radical SAM domain protein K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004551 243.0
MMD2_k127_5498866_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007384 320.0
MMD2_k127_5498866_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000001665 102.0
MMD2_k127_5498866_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000577 82.0
MMD2_k127_5512302_0 SMART Elongator protein 3 MiaB NifB K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 426.0
MMD2_k127_5512302_1 Multicopper - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 421.0
MMD2_k127_5512302_2 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 343.0
MMD2_k127_5512302_3 AsnC-type helix-turn-helix domain K05710 - - 0.000000000000000000000000000000000000000000000000002344 203.0
MMD2_k127_5525536_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 584.0
MMD2_k127_5525536_1 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001188 283.0
MMD2_k127_5525536_2 STAS domain - - - 0.000000000003152 71.0
MMD2_k127_5547007_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 434.0
MMD2_k127_5547007_1 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006039 284.0
MMD2_k127_5557192_0 PFAM chaperonin Cpn60 TCP-1 K22447 - - 6.674e-281 871.0
MMD2_k127_5557192_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 596.0
MMD2_k127_5557192_10 - - - - 0.00000000000315 70.0
MMD2_k127_5557192_11 methyl-accepting chemotaxis protein K03406,K07652 - 2.7.13.3 0.000007889 54.0
MMD2_k127_5557192_2 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 477.0
MMD2_k127_5557192_3 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 420.0
MMD2_k127_5557192_4 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 415.0
MMD2_k127_5557192_5 HTH-type transcriptional regulatory protein K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 355.0
MMD2_k127_5557192_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000003174 258.0
MMD2_k127_5557192_7 Roadblock LC7 - - - 0.0000000000000000000000000000000000008557 149.0
MMD2_k127_5557192_8 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171,K00188 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000001695 139.0
MMD2_k127_5557192_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K18357 - 1.2.1.58,1.2.7.1 0.00000000000000000000000000000000002625 140.0
MMD2_k127_5559625_0 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 351.0
MMD2_k127_5565701_0 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 335.0
MMD2_k127_5565701_1 COG1361 S-layer domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 312.0
MMD2_k127_5565701_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009227 282.0
MMD2_k127_5565701_3 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000006366 193.0
MMD2_k127_5565701_4 Domain of unknown function (DUF1805) - - - 0.0000000000000000000000000000003542 125.0
MMD2_k127_5565701_5 SPTR Large low complexity protein with proline alanine-rich repeat - - - 0.00001374 53.0
MMD2_k127_5578467_0 PFAM major facilitator superfamily MFS_1 K08177 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 444.0
MMD2_k127_5578467_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.000000000000000000000000000000000000000000000000000000000000000000000013 246.0
MMD2_k127_5578467_2 Located on the platform of the 30S subunit K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005346 238.0
MMD2_k127_5578467_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000000000000005453 213.0
MMD2_k127_5578467_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000003022 181.0
MMD2_k127_5578467_5 Plasmid pRiA4b ORF-3-like protein - - - 0.00000000007609 63.0
MMD2_k127_5607668_0 Transport of potassium into the cell K03549 - - 1.124e-264 827.0
MMD2_k127_5607668_1 UPF0056 membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000005583 223.0
MMD2_k127_5607668_2 Sodium/hydrogen exchanger family - - - 0.000000000000000000006234 106.0
MMD2_k127_5607668_3 - - - - 0.0000000003464 63.0
MMD2_k127_5607668_4 HEAT repeats - - - 0.000000003995 61.0
MMD2_k127_5610144_0 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 489.0
MMD2_k127_5610144_1 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 487.0
MMD2_k127_5610144_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 455.0
MMD2_k127_5610144_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 443.0
MMD2_k127_5610144_4 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004635 422.0
MMD2_k127_5610144_5 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 361.0
MMD2_k127_5610144_6 Oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001115 260.0
MMD2_k127_5610144_7 - - - - 0.000000000000000000000004448 113.0
MMD2_k127_5631183_0 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003122 395.0
MMD2_k127_5631183_1 transcription termination protein NusA K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000165 229.0
MMD2_k127_5631183_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000007768 169.0
MMD2_k127_5631183_3 phosphoribosyl-ATP pyrophosphohydrolase K01523 - 3.6.1.31 0.00000000000000000000000003343 111.0
MMD2_k127_5631715_0 PFAM multi antimicrobial extrusion protein MatE - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 440.0
MMD2_k127_5679284_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 448.0
MMD2_k127_5679284_1 inorganic K15986 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009483 322.0
MMD2_k127_5681585_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0 1021.0
MMD2_k127_5681585_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000226 130.0
MMD2_k127_5681585_2 PspC domain K03973 - - 0.000000000000000001136 88.0
MMD2_k127_5729613_0 Co Zn Cd efflux system component K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 339.0
MMD2_k127_5729613_1 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000002407 177.0
MMD2_k127_5729613_3 - - - - 0.00000000007852 70.0
MMD2_k127_5749901_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000846 162.0
MMD2_k127_5749901_1 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.00000000005196 74.0
MMD2_k127_578036_0 Protein of unknown function (DUF1646) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 446.0
MMD2_k127_578036_1 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 326.0
MMD2_k127_578036_2 PBS lyase K22221 - - 0.000000000000000000000000000000000000000000000000000004708 208.0
MMD2_k127_578036_3 COG0589 Universal stress protein UspA and related nucleotide-binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000003656 184.0
MMD2_k127_578036_4 Protein of unknown function (DUF432) K09149 - - 0.00000000000000000000000000000000000000002386 157.0
MMD2_k127_5803487_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 7.91e-203 655.0
MMD2_k127_5803487_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005606 586.0
MMD2_k127_5803487_2 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 581.0
MMD2_k127_5803487_3 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 472.0
MMD2_k127_5803487_4 - - - - 0.000000000000000000000000000000000000000000628 162.0
MMD2_k127_5803487_5 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.000000000000000001197 87.0
MMD2_k127_5803487_6 - - - - 0.000000000000000003439 84.0
MMD2_k127_5803487_7 SigmaK-factor processing regulatory protein BofA - - - 0.000000000000001327 79.0
MMD2_k127_5813361_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 343.0
MMD2_k127_5813361_1 - - - - 0.0000000000000000000000000000000000000000000000000000000002753 214.0
MMD2_k127_583569_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 536.0
MMD2_k127_583569_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 291.0
MMD2_k127_583569_2 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000004315 81.0
MMD2_k127_5838414_0 Belongs to the TPP enzyme family K00158 - 1.2.3.3 1.031e-228 724.0
MMD2_k127_5838414_1 Belongs to the glutamate synthase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 518.0
MMD2_k127_584187_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008978 310.0
MMD2_k127_584187_1 Belongs to the UPF0173 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 297.0
MMD2_k127_584187_2 PFAM tRNA synthetase, class II (G, H, P and S) K01880 - 6.1.1.14 0.0000000000000000000000000000000000001509 141.0
MMD2_k127_584187_3 metallopeptidase activity - - - 0.0000000000000000000000000004498 122.0
MMD2_k127_5854800_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 428.0
MMD2_k127_5854800_1 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 311.0
MMD2_k127_5854800_2 Transcriptional regulator K07722 - - 0.00000000000000000000000000000000000000000000000000000000000000000007489 232.0
MMD2_k127_5854800_3 Uncharacterized protein conserved in archaea (DUF2098) - - - 0.0000000000000000000004997 100.0
MMD2_k127_5855168_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 600.0
MMD2_k127_5855168_1 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 349.0
MMD2_k127_5855168_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 305.0
MMD2_k127_5855168_3 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000875 252.0
MMD2_k127_5855168_4 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000009803 160.0
MMD2_k127_5872142_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0 1002.0
MMD2_k127_5872142_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.853e-266 824.0
MMD2_k127_5872142_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 580.0
MMD2_k127_5872142_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 319.0
MMD2_k127_5872142_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006035 294.0
MMD2_k127_5872142_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000000000000000000000000000000000146 168.0
MMD2_k127_5872142_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000000000000000000000001518 154.0
MMD2_k127_5872142_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000002857 133.0
MMD2_k127_5879799_0 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008269 368.0
MMD2_k127_5879799_1 4Fe-4S dicluster domain K11260,K14107 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003823 269.0
MMD2_k127_5879799_2 PFAM molydopterin dinucleotide-binding region K00203 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.2.7.12 0.000000000000000000000000002003 115.0
MMD2_k127_588014_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000002808 231.0
MMD2_k127_588014_1 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000000006176 188.0
MMD2_k127_588014_2 protein kinase activity - - - 0.000000009533 64.0
MMD2_k127_5883667_0 aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009403 507.0
MMD2_k127_5883667_1 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000005053 179.0
MMD2_k127_5927820_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.079e-257 805.0
MMD2_k127_5927820_1 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000009174 87.0
MMD2_k127_594322_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 1.73e-321 987.0
MMD2_k127_594322_1 Uncharacterized protein conserved in archaea (DUF2114) - - - 1.446e-259 809.0
MMD2_k127_594322_2 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 583.0
MMD2_k127_594322_3 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 428.0
MMD2_k127_594322_4 - - - - 0.000000000000000000003564 94.0
MMD2_k127_5976791_0 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000001441 268.0
MMD2_k127_5976791_1 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000002588 243.0
MMD2_k127_5976791_2 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000003368 181.0
MMD2_k127_5976791_3 PFAM Thioredoxin K03671 - - 0.000000000000000000000000000000000000223 141.0
MMD2_k127_5976791_4 PFAM HhH-GPD K07457 - - 0.0000000000000000000000000000000004627 139.0
MMD2_k127_5976791_5 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000001106 83.0
MMD2_k127_6018311_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 560.0
MMD2_k127_6018311_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 537.0
MMD2_k127_6018311_2 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 293.0
MMD2_k127_6018311_3 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000001493 235.0
MMD2_k127_6018311_4 membrane protein (DUF2178) - - - 0.00000000000000000000000000000000000000000000000002128 183.0
MMD2_k127_6018311_5 Protein of unknown function (DUF1622) - - - 0.000000000000000000000003211 106.0
MMD2_k127_6018311_6 Molybdopterin converting factor, small subunit K03636 - - 0.000000000000000002873 89.0
MMD2_k127_6018311_7 Transcriptional K07729 - - 0.000000000000003003 78.0
MMD2_k127_6018311_8 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.000000003839 64.0
MMD2_k127_6028321_0 - - - - 0.0000000000000000000000000000000000000000000000001539 190.0
MMD2_k127_6028321_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000004791 175.0
MMD2_k127_6028321_2 - - - - 0.000000000000000000000000000000000000000000006721 177.0
MMD2_k127_6028321_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K18979 - 1.17.99.6 0.00000000000000000000004291 111.0
MMD2_k127_6028321_4 - - - - 0.00000000000003794 74.0
MMD2_k127_6028321_5 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0000000000002328 72.0
MMD2_k127_6054776_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 1.015e-266 838.0
MMD2_k127_6054776_1 Protein of unknown function, DUF255 K06888 - - 7.091e-197 635.0
MMD2_k127_6054776_2 Rhodanese-like domain K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 500.0
MMD2_k127_6054776_3 PFAM HhH-GPD family protein K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008963 317.0
MMD2_k127_6054776_4 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 300.0
MMD2_k127_6054776_5 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07005 - - 0.000000000000000000000000000000000000000000000000000000000000000000001371 241.0
MMD2_k127_6054776_6 Belongs to the N(4) N(6)-methyltransferase family K00571 - 2.1.1.72 0.00002074 47.0
MMD2_k127_6077885_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1168.0
MMD2_k127_6077885_1 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 309.0
MMD2_k127_6077885_2 Domain in cystathionine beta-synthase and other proteins. K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 306.0
MMD2_k127_6077885_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000004338 173.0
MMD2_k127_6077885_4 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.000000009078 57.0
MMD2_k127_6089694_0 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 309.0
MMD2_k127_6089694_1 PFAM metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
MMD2_k127_6089694_2 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001928 276.0
MMD2_k127_6089694_3 PFAM peptidylprolyl isomerase FKBP-type K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000036 256.0
MMD2_k127_6089694_4 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000001026 205.0
MMD2_k127_6089694_5 adenylyl cyclase CyaB K05873 - 4.6.1.1 0.000000000000000000000000000000000000000000000257 173.0
MMD2_k127_6089694_6 PFAM peptidase U32 K08303 - - 0.0000000000001532 76.0
MMD2_k127_6102256_0 Helix-hairpin-helix domain K02347 - - 9.213e-214 679.0
MMD2_k127_6102256_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 444.0
MMD2_k127_6102256_2 Flavodoxin-like fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 289.0
MMD2_k127_6102256_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001615 265.0
MMD2_k127_6102256_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000001047 162.0
MMD2_k127_6102256_5 SMART Elongator protein 3 MiaB NifB K06936 - - 0.000000000000000000000000000000000006084 142.0
MMD2_k127_6102256_6 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000000000368 129.0
MMD2_k127_6110731_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 314.0
MMD2_k127_6110731_1 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000002395 225.0
MMD2_k127_6110731_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000007885 213.0
MMD2_k127_6110731_3 - - - - 0.0000003712 59.0
MMD2_k127_6110731_4 methyltransferase - - - 0.0001567 53.0
MMD2_k127_6114265_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 484.0
MMD2_k127_6114265_1 B-block binding subunit of TFIIIC - - - 0.0000000000000000000000000000000000000000000000004617 177.0
MMD2_k127_6114265_2 PFAM Like-Sm ribonucleoprotein, core - - - 0.000000000000000000000000000000000138 133.0
MMD2_k127_6115899_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.796e-299 943.0
MMD2_k127_6115899_1 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 580.0
MMD2_k127_6115899_2 AN1-like Zinc finger - - - 0.000000000000000001538 96.0
MMD2_k127_6118215_0 Formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.483e-239 743.0
MMD2_k127_6118215_1 Hydantoinase/oxoprolinase K07072 - 2.5.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 349.0
MMD2_k127_6118215_2 ATP-grasp domain K06914 - 6.3.4.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 354.0
MMD2_k127_6118215_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 329.0
MMD2_k127_6118215_4 - - - - 0.0000000000000000000000000000000000000000000007216 175.0
MMD2_k127_6119585_0 Formylmethanofuran dehydrogenase subunit A K00200 - 1.2.7.12 7.215e-221 694.0
MMD2_k127_6119585_1 Formylmethanofuran dehydrogenase, subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 510.0
MMD2_k127_6124813_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 2.453e-258 805.0
MMD2_k127_6161552_0 ATPases associated with a variety of cellular activities K02006 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 381.0
MMD2_k127_6161552_1 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008027 272.0
MMD2_k127_6161552_2 Cobalt transport protein K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003153 267.0
MMD2_k127_6161552_4 iron dependent repressor K03709 - - 0.00000000000000000000000000000000000000000000000000000002481 202.0
MMD2_k127_6161552_5 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07006 - - 0.000000000000000000000000000000000000000006266 156.0
MMD2_k127_6161552_7 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00004913 47.0
MMD2_k127_618969_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1226.0
MMD2_k127_618969_1 PFAM PilT protein domain protein K06865 - - 0.0000000004657 60.0
MMD2_k127_6229262_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 7.958e-232 730.0
MMD2_k127_6229262_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 530.0
MMD2_k127_6229262_2 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 - 3.5.4.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
MMD2_k127_6235143_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 - 2.7.7.6 0.0 1256.0
MMD2_k127_6235143_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 1.321e-195 615.0
MMD2_k127_6235143_2 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000000000000000001764 125.0
MMD2_k127_6235143_3 transcription termination protein NusA K02600 - - 0.00000000000000000000000000558 112.0
MMD2_k127_6247021_0 SMART Elongator protein 3 MiaB NifB - - - 9.303e-258 808.0
MMD2_k127_6247021_1 Methyltransferase domain - - - 0.000000000000000000006285 93.0
MMD2_k127_6275945_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006492 491.0
MMD2_k127_6275945_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 473.0
MMD2_k127_6275945_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014,K00891,K03785 - 1.1.1.25,2.7.1.71,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007446 432.0
MMD2_k127_6275945_3 Prephenate dehydratase K04518 - 4.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 325.0
MMD2_k127_6275945_4 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 304.0
MMD2_k127_6275945_5 Catalyzes the oxidative deamination and cyclization of 2-amino-3,7-dideoxy-D-threo-hept-6-ulosonic acid (ADH) to yield 3- dehydroquinate (DHQ), which is fed into the canonical shikimic pathway of aromatic amino acid biosynthesis K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006021 292.0
MMD2_k127_6275945_6 beta-lactamase domain protein - - - 0.000000000000005486 76.0
MMD2_k127_68141_0 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05934 - 2.1.1.131 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004406 294.0
MMD2_k127_68141_1 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K05936 - 2.1.1.133,2.1.1.271 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002484 291.0
MMD2_k127_68141_2 PFAM Uroporphyrin-III C tetrapyrrole (Corrin Porphyrin) methyltransferase K03394 - 2.1.1.130,2.1.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000006934 250.0
MMD2_k127_68141_3 PFAM Precorrin-8X methylmutase CbiC CobH K06042 - 5.4.99.60,5.4.99.61 0.00000000000000000000000000000000000000000000000000000088 199.0
MMD2_k127_68141_4 Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin- 7 K02191 - 2.1.1.196 0.0000000000000000000000000000000000000002645 155.0
MMD2_k127_68141_5 Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A K02188 - 2.1.1.195 0.000000000000000000000000002701 114.0
MMD2_k127_68141_6 PFAM cobalamin (vitamin B12) biosynthesis CbiG protein K02189 - 3.7.1.12 0.00000000000000000000000001148 121.0
MMD2_k127_68141_7 small multi-drug export - - - 0.000000000000000000000001542 107.0
MMD2_k127_689892_0 Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005593 565.0
MMD2_k127_689892_1 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 322.0
MMD2_k127_689892_2 - - - - 0.00000000000000000000176 96.0
MMD2_k127_689892_3 Belongs to the UPF0251 family K06933 - - 0.00004522 49.0
MMD2_k127_719637_0 in RNase L inhibitor, RLI K06174 - - 1.861e-285 886.0
MMD2_k127_719637_1 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 1.368e-227 724.0
MMD2_k127_719637_10 RNase L inhibitor, RLI - - - 0.0000000000000000000000000000001183 131.0
MMD2_k127_719637_11 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000004531 87.0
MMD2_k127_719637_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 374.0
MMD2_k127_719637_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 354.0
MMD2_k127_719637_4 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 351.0
MMD2_k127_719637_5 Chemotaxis signal transduction system protein F from archaea K09156 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 344.0
MMD2_k127_719637_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004812 259.0
MMD2_k127_719637_7 PFAM response regulator receiver K03413 - - 0.00000000000000000000000000000000000000000000000000000000000001279 216.0
MMD2_k127_719637_8 CheC inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000000000000000000000001701 192.0
MMD2_k127_719637_9 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000003785 169.0
MMD2_k127_735915_0 PFAM elongation factor Tu domain 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 352.0
MMD2_k127_735915_1 Metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000001178 219.0
MMD2_k127_735915_2 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000000001823 162.0
MMD2_k127_770628_0 SMART PAS domain containing protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 576.0
MMD2_k127_770628_1 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 550.0
MMD2_k127_770628_2 PFAM CheW domain protein K03408 - - 0.0000000000000000000000000000000000000000000007265 170.0
MMD2_k127_770628_3 - - - - 0.00000000000000004779 86.0
MMD2_k127_775689_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 3.35e-202 640.0
MMD2_k127_775689_1 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000002008 157.0
MMD2_k127_816655_0 PFAM Multicopper oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001947 288.0
MMD2_k127_816655_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like - - - 0.00000000000000000000000000000003222 134.0
MMD2_k127_816655_2 - - - - 0.0000000000000000000000000005946 119.0
MMD2_k127_816655_3 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00000000000000000000000003693 111.0
MMD2_k127_816655_4 Stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000001493 84.0
MMD2_k127_83855_0 SMART Elongator protein 3 MiaB NifB - - - 6.972e-231 727.0
MMD2_k127_83855_1 phosphoesterase RecJ domain protein - - - 3.788e-216 680.0
MMD2_k127_83855_2 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 475.0
MMD2_k127_83855_3 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 293.0
MMD2_k127_83855_4 PFAM PRC-barrel domain - - - 0.00000000000000000000000000000006393 126.0
MMD2_k127_83855_5 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000006598 129.0
MMD2_k127_83855_7 tRNAHis guanylyltransferase - - - 0.0000000000001806 74.0
MMD2_k127_839798_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.32e-259 807.0
MMD2_k127_839798_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 567.0
MMD2_k127_839798_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000001819 136.0
MMD2_k127_839798_11 response regulator, receiver - - - 0.00000000000000000000000002001 126.0
MMD2_k127_839798_12 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000002872 87.0
MMD2_k127_839798_13 - - - - 0.000000000000000004303 92.0
MMD2_k127_839798_14 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000001045 68.0
MMD2_k127_839798_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 486.0
MMD2_k127_839798_3 PFAM Aminotransferase class I and II K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 384.0
MMD2_k127_839798_4 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 308.0
MMD2_k127_839798_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002346 267.0
MMD2_k127_839798_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000003346 225.0
MMD2_k127_839798_7 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000001879 201.0
MMD2_k127_839798_8 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000001082 183.0
MMD2_k127_839798_9 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000006073 156.0
MMD2_k127_872157_0 AAA-like domain K06915 - - 9.566e-227 715.0
MMD2_k127_872157_1 coenzyme F420 hydrogenase dehydrogenase beta subunit domain protein K00125 - 1.17.1.9 4.089e-207 652.0
MMD2_k127_872157_2 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing K00123,K00367,K00372,K08356 - 1.17.1.9,1.20.2.1,1.20.9.1,1.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 449.0
MMD2_k127_872157_3 PFAM formate nitrite transporter K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 439.0
MMD2_k127_872157_4 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005847 286.0
MMD2_k127_872157_5 PFAM nucleic acid binding, OB-fold, tRNA helicase-type - - - 0.00000000000000000000000000000000000000000000000000000001826 205.0
MMD2_k127_872157_6 - - - - 0.0000000000000001463 86.0
MMD2_k127_874089_0 Belongs to the N(4) N(6)-methyltransferase family K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002048 414.0
MMD2_k127_874089_1 PFAM PEGA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002635 286.0
MMD2_k127_874089_2 Domain of unknown function (DUF1724) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005264 264.0
MMD2_k127_874089_3 sugar phosphatases of the HAD superfamily K02566 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006112 245.0
MMD2_k127_874089_4 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000002074 208.0
MMD2_k127_874089_5 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000135 149.0
MMD2_k127_874089_6 PFAM ABC transporter K09013 - - 0.00000000000000000000007405 99.0
MMD2_k127_874311_0 TIGRFAM 26S proteasome subunit P45 family K03420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 334.0
MMD2_k127_874311_1 Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000003383 196.0
MMD2_k127_874311_2 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000000000000001031 181.0
MMD2_k127_903917_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 535.0
MMD2_k127_903917_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 453.0
MMD2_k127_903917_2 Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis- homo(3)-aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B K16793 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000003073 224.0
MMD2_k127_903917_3 - - - - 0.000000001171 64.0
MMD2_k127_943742_0 DEAD DEAH box helicase domain protein K10896 - - 0.0000000000000000000000000000000000000000000002515 170.0
MMD2_k127_943742_1 Belongs to the UPF0147 family K09721 - - 0.0000000000000000000000000000000000000001961 151.0
MMD2_k127_943742_2 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000000000000000000001308 118.0
MMD2_k127_943742_3 epoxide hydrolase K21159 - - 0.00006319 49.0
MMD2_k127_966127_0 PFAM PilT protein domain protein K06865 - - 1.211e-266 831.0
MMD2_k127_966127_1 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.0000000000000000000000000000000000000000000000003309 177.0
MMD2_k127_970529_0 Succinate dehydrogenase fumarate reductase flavoprotein subunit K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 7.459e-241 754.0
MMD2_k127_970529_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 2.832e-218 688.0
MMD2_k127_970529_10 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 350.0
MMD2_k127_970529_11 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 311.0
MMD2_k127_970529_12 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 310.0
MMD2_k127_970529_13 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 291.0
MMD2_k127_970529_14 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 284.0
MMD2_k127_970529_15 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003683 271.0
MMD2_k127_970529_16 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
MMD2_k127_970529_17 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000002279 226.0
MMD2_k127_970529_18 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000000000000000000000000000000000000001325 200.0
MMD2_k127_970529_19 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000001432 199.0
MMD2_k127_970529_2 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K18210 - 1.3.4.1 1.538e-214 679.0
MMD2_k127_970529_20 Pfam:DUF552 K09152 - - 0.000000000000000000000000000000000000000000000000000005445 192.0
MMD2_k127_970529_21 ZPR1-related zinc finger protein K06874 - - 0.0000000000000000000000000000000000000000000000000002081 190.0
MMD2_k127_970529_22 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000007661 188.0
MMD2_k127_970529_23 Thioredoxin K03671 - - 0.00000000000000000000000000000000000000000001218 165.0
MMD2_k127_970529_24 PFAM phosphatidate cytidylyltransferase - - - 0.00000000000000000000000000000000000000000003916 168.0
MMD2_k127_970529_25 PFAM Carboxymuconolactone decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000005376 163.0
MMD2_k127_970529_26 PFAM Like-Sm ribonucleoprotein, core K04796 - - 0.00000000000000000000000000000000006819 134.0
MMD2_k127_970529_27 PFAM transcriptional coactivator pterin dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000005299 119.0
MMD2_k127_970529_28 Zinc-ribbon containing domain - - - 0.00000000000000000000000000133 113.0
MMD2_k127_970529_29 chorismate mutase K04093 - 5.4.99.5 0.000000000000000000000000005133 116.0
MMD2_k127_970529_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.258e-204 644.0
MMD2_k127_970529_30 binds to the 23S rRNA K02922 - - 0.00000000000000000000000001395 109.0
MMD2_k127_970529_31 - - - - 0.00000000000000000002079 98.0
MMD2_k127_970529_32 PFAM Desulfoferrodoxin Dfx domain protein - - - 0.00000000000001853 73.0
MMD2_k127_970529_33 - - - - 0.0000003037 53.0
MMD2_k127_970529_4 Belongs to the aspartokinase family K00928 - 2.7.2.4 4.492e-197 624.0
MMD2_k127_970529_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 505.0
MMD2_k127_970529_6 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 467.0
MMD2_k127_970529_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384,K03387 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 458.0
MMD2_k127_970529_8 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006072 408.0
MMD2_k127_970529_9 Belongs to the N(4) N(6)-methyltransferase family K00571,K00590 - 2.1.1.113,2.1.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 360.0
MMD2_k127_974435_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 335.0
MMD2_k127_974435_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 300.0
MMD2_k127_974435_2 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.101 0.000000000000000001085 87.0
MMD2_k127_98594_0 Glutathione synthase ribosomal protein S6 modification enzyme (Glutaminyl transferase) K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 416.0
MMD2_k127_98594_1 PFAM glutamate--cysteine ligase, GCS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 395.0
MMD2_k127_98594_2 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 288.0
MMD2_k127_98594_3 arsenite transmembrane transporter activity K03893 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008490,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042960,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 - 0.0000000000000000000000000000000000000000000000000000000000000000000000009091 267.0
MMD2_k127_98594_4 RimK-like ATPgrasp N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000008494 212.0
MMD2_k127_98594_5 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000001409 160.0
MMD2_k127_98594_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001472 149.0
MMD2_k127_98594_7 EamA-like transporter family - - - 0.00000000000000000000000000007052 127.0
MMD2_k127_98594_8 Tetratricopeptide repeat - - - 0.000000000000000002481 93.0
MMD2_k127_987577_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 388.0
MMD2_k127_987577_1 PFAM Shwachman-Bodian-Diamond syndrome K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 360.0
MMD2_k127_987577_2 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000000000000000000000000000004055 153.0
MMD2_k127_987577_3 binds to the 23S rRNA K02921 - - 0.000000000000000000000000000000000009163 142.0
MMD2_k127_987577_4 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.00000000000000000000000000000000006364 137.0
MMD2_k127_987577_5 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00000000000000000000000000000000058 136.0
MMD2_k127_987577_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000000000000002779 90.0
MMD2_k127_987577_7 protein conserved in archaea K09741 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000138 82.0