Overview

ID MAG02369
Name MMD2_bin.35
Sample SMP0059
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class DTKX01
Order DTKX01
Family GCA-020343715
Genus
Species
Assembly information
Completeness (%) 73.05
Contamination (%) 0.86
GC content (%) 69.0
N50 (bp) 4,244
Genome size (bp) 2,470,394

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1799

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1013784_0 PFAM Type II secretion system protein E K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 595.0
MMD2_k127_1013784_1 pyridoxal phosphate-dependent acyltransferase K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 432.0
MMD2_k127_1013784_2 KaiC K07331 - - 0.00000000000000000000000000000000000000000000000000000000002653 213.0
MMD2_k127_1013784_3 PFAM ATP-NAD AcoX kinase - - - 0.0000000000000000000002097 99.0
MMD2_k127_1013784_4 Flagellin is the subunit protein which polymerizes to form the filaments of archaeal flagella K07325 GO:0005575,GO:0005623,GO:0009288,GO:0042995,GO:0043226,GO:0043228,GO:0044464 - 0.0000000000000000083 91.0
MMD2_k127_1013784_5 Flagella accessory protein C (FlaC) K07327,K07328 - - 0.00000000000000004694 94.0
MMD2_k127_1013784_6 archaeal flagellar protein F K07329 - - 0.000000000003264 72.0
MMD2_k127_1013784_7 archaeal flagellar protein G K07330 - - 0.000000000125 68.0
MMD2_k127_1039775_0 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.0000000000000000000000000000000000000000000000006467 201.0
MMD2_k127_1039775_1 amine dehydrogenase activity K20276 - - 0.0000000000000000000000000000000000001063 165.0
MMD2_k127_1046962_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000006815 138.0
MMD2_k127_1046962_1 SMART Parallel beta-helix repeat - - - 0.000000000000000000000000000000001681 151.0
MMD2_k127_1058205_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 411.0
MMD2_k127_1058205_1 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.000000000000000000000000000000000000000000000000001437 189.0
MMD2_k127_1066720_0 geranylgeranyl reductase - - - 0.000000000003113 76.0
MMD2_k127_1082734_0 RNA recognition motif - - - 0.0000000000000000000000000004668 114.0
MMD2_k127_1082734_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000395 83.0
MMD2_k127_1082734_2 PFAM ABC-2 type transporter K09694 - - 0.000000001448 60.0
MMD2_k127_1110199_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006506 350.0
MMD2_k127_1110199_1 PFAM Ribosomal L18ae LX protein domain K02944 - - 0.00000004857 57.0
MMD2_k127_1110199_2 Metallophosphoesterase, calcineurin superfamily - - - 0.00000006206 63.0
MMD2_k127_1110199_3 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000002342 61.0
MMD2_k127_1112284_0 small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000005885 224.0
MMD2_k127_1112284_1 KaiC K08482 - - 0.0000000000000000000000000000000002597 140.0
MMD2_k127_1112284_2 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0005772 49.0
MMD2_k127_1120728_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 497.0
MMD2_k127_1120728_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 424.0
MMD2_k127_1120728_2 archaeal coiled-coil protein - - - 0.000000000000000000000000000000000000000000000000007315 197.0
MMD2_k127_1120728_3 Serine protease with a broad substrate specificity K13276,K17734 - - 0.0000000000000000000000000000000000000000000002715 193.0
MMD2_k127_1120728_4 UbiA prenyltransferase family K04040 - 2.5.1.133,2.5.1.62 0.000000000000000000000000007582 123.0
MMD2_k127_1120728_5 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.000000000000000000000000734 121.0
MMD2_k127_1120728_6 PFAM NHL repeat containing protein - - - 0.000000000000000000000007631 119.0
MMD2_k127_1120728_7 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 - 3.1.26.5 0.0000000000000006539 85.0
MMD2_k127_1120728_8 Subtilase family - - - 0.000000000001454 80.0
MMD2_k127_1120728_9 RNA-binding protein containing KH domain, possibly ribosomal protein K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.0000063 57.0
MMD2_k127_1130590_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 459.0
MMD2_k127_1130590_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 414.0
MMD2_k127_1130590_10 Beta-eliminating lyase K04487 - 2.8.1.7 0.0007487 45.0
MMD2_k127_1130590_2 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005699 269.0
MMD2_k127_1130590_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000049 267.0
MMD2_k127_1130590_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000009625 198.0
MMD2_k127_1130590_5 Transcription elongation factor Spt5 K02601 - - 0.0000000000000000000000000000000000000006915 159.0
MMD2_k127_1130590_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000002949 114.0
MMD2_k127_1130590_7 Major Facilitator Superfamily - - - 0.0000000000000000002768 101.0
MMD2_k127_1130590_8 - - - - 0.0000000000000003893 84.0
MMD2_k127_1130590_9 TIGRFAM protein translocase SEC61 complex gamma subunit K07342 - - 0.00007035 49.0
MMD2_k127_1136153_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 469.0
MMD2_k127_1136153_1 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000001073 226.0
MMD2_k127_1136153_2 Belongs to the thioredoxin family K03671 - - 0.000000000001005 69.0
MMD2_k127_1136554_0 Belongs to the peptidase S8 family - - - 0.00000000005094 77.0
MMD2_k127_1147835_0 FtsX-like permease family K02004 - - 0.00000000000000003558 94.0
MMD2_k127_1147835_1 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.00000003296 64.0
MMD2_k127_1147835_2 PA14 domain - - - 0.000003559 61.0
MMD2_k127_1147835_3 Domain of unknown function (DUF4082) - - - 0.00001414 59.0
MMD2_k127_1147835_4 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0005507 53.0
MMD2_k127_115986_0 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000000003792 91.0
MMD2_k127_115986_1 TIGRFAM Outer membrane protein K20276 - - 0.00000000000000779 90.0
MMD2_k127_115986_2 Endonuclease I - - - 0.0000000000685 72.0
MMD2_k127_1175704_0 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000009621 246.0
MMD2_k127_1175704_1 PFAM UbiA prenyltransferase K02548 - 2.5.1.74 0.0000000000000000000000000001804 121.0
MMD2_k127_1178569_0 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000009695 157.0
MMD2_k127_1178569_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.000000000000000000000004115 110.0
MMD2_k127_1178569_2 Integral membrane protein DUF106 - - - 0.0000000000000000000000113 109.0
MMD2_k127_1180899_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 312.0
MMD2_k127_1180899_1 GMP synthase C terminal domain K01951 - 6.3.5.2 0.000000000000000000001225 94.0
MMD2_k127_1193985_0 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000004572 216.0
MMD2_k127_1193985_1 tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000002774 202.0
MMD2_k127_1193985_2 Major Facilitator Superfamily - - - 0.000000000000000000008892 102.0
MMD2_k127_1194415_0 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.000000000000000000000000000005831 122.0
MMD2_k127_1194415_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K18824 GO:0003674,GO:0003824,GO:0004156,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.15 0.000000000000009873 80.0
MMD2_k127_1194601_0 4Fe-4S single cluster domain K07129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006158 273.0
MMD2_k127_1194601_1 Mg2 transporter-C family protein K07507 - - 0.000000000000000000000000000000002757 137.0
MMD2_k127_1194601_2 PFAM PKD domain containing protein - - - 0.00000000000002141 86.0
MMD2_k127_1220347_0 4Fe-4S ferredoxin - - - 0.000000000000000000000000006066 129.0
MMD2_k127_1220347_1 Ethylbenzene dehydrogenase - - - 0.00000000000000000008587 106.0
MMD2_k127_1220347_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000001014 82.0
MMD2_k127_1220347_3 PA14 domain - - - 0.000006507 60.0
MMD2_k127_1221649_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001022 247.0
MMD2_k127_1224376_0 Carboxyl transferase domain - - - 9.827e-238 743.0
MMD2_k127_1224376_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000002503 235.0
MMD2_k127_1224376_2 Enoyl-CoA hydratase/isomerase - GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.000000000000000001799 85.0
MMD2_k127_1273169_0 Redoxin domain protein - - - 0.000000000000007784 85.0
MMD2_k127_1273169_1 - - - - 0.00000006275 57.0
MMD2_k127_1277204_0 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000254 210.0
MMD2_k127_1296958_0 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000000002281 157.0
MMD2_k127_1296958_1 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000001574 121.0
MMD2_k127_1296958_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000001281 121.0
MMD2_k127_1296958_3 - - - - 0.000000264 60.0
MMD2_k127_1302890_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 285.0
MMD2_k127_1302890_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000008679 212.0
MMD2_k127_1302890_2 pfkB family carbohydrate kinase K22026 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006213,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008617,GO:0008906,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009129,GO:0009130,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034404,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042278,GO:0042455,GO:0043167,GO:0043168,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046033,GO:0046035,GO:0046085,GO:0046087,GO:0046102,GO:0046128,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901068,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:1905108 2.7.1.213,2.7.1.73 0.0000000000000000000000000000000000000000000000009207 198.0
MMD2_k127_1302890_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000005359 147.0
MMD2_k127_1302890_4 Histone deacetylase domain K04768 - - 0.0000001356 58.0
MMD2_k127_130378_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 484.0
MMD2_k127_130378_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000001168 179.0
MMD2_k127_130378_2 NTPase K06928 - 3.6.1.15 0.0000000000000000000000000000000001935 142.0
MMD2_k127_132115_0 AMMECR1 K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000001453 240.0
MMD2_k127_132115_1 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.0000000000000000000000001146 111.0
MMD2_k127_132115_2 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000003762 102.0
MMD2_k127_132115_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000006158 86.0
MMD2_k127_132115_4 Lrp/AsnC ligand binding domain - - - 0.0009972 48.0
MMD2_k127_1325811_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000006727 147.0
MMD2_k127_1325811_1 - - - - 0.00000000000002741 79.0
MMD2_k127_1325811_2 metal-dependent membrane protease K07052 - - 0.00000000005349 72.0
MMD2_k127_1329957_0 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000004706 246.0
MMD2_k127_1329957_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000001511 208.0
MMD2_k127_1329957_2 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000148 179.0
MMD2_k127_1329957_3 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171,K00188 - 1.2.7.1,1.2.7.7 0.000000000000000000000000803 108.0
MMD2_k127_1340186_0 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004232 388.0
MMD2_k127_1347991_0 KH domain K07041 - - 4.883e-258 810.0
MMD2_k127_1347991_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000000000000004159 224.0
MMD2_k127_1348875_0 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001053 291.0
MMD2_k127_1348875_1 Catalyzes a transaldol reaction between 6-deoxy-5- ketofructose 1-phosphate (DKFP) and L-aspartate semialdehyde (ASA) with an elimination of hydroxypyruvaldehyde phosphate to yield 2- amino-3,7-dideoxy-D-threo-hept-6-ulosonate (ADH). Plays a key role in an alternative pathway of the biosynthesis of 3-dehydroquinate (DHQ), which is involved in the canonical pathway for the biosynthesis of aromatic amino acids K16306 - 2.2.1.10,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000006872 243.0
MMD2_k127_1348875_2 Thioesterase domain - - - 0.000000000000000000000003141 113.0
MMD2_k127_1348875_3 PFAM Polysaccharide pyruvyl transferase - - - 0.0000000000000000000003442 98.0
MMD2_k127_1348875_4 PFAM 3-dehydroquinate synthase K11646 - 1.4.1.24 0.0000000002483 68.0
MMD2_k127_1354450_0 Protein of unknown function DUF86 K07075 - - 0.0000000000000000000000000007894 114.0
MMD2_k127_1354450_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.000000000000000000000002352 104.0
MMD2_k127_1354450_2 PFAM DNA polymerase, beta domain protein region K07075 - - 0.000000000000000000000009605 105.0
MMD2_k127_1354450_3 hydrolase activity, acting on ester bonds K01259 - 3.4.11.5 0.0000000000001697 81.0
MMD2_k127_1356822_0 acyl-coa dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000001859 220.0
MMD2_k127_1358928_0 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000006696 191.0
MMD2_k127_1358928_1 PFAM acylneuraminate cytidylyltransferase K00983 - 2.7.7.43 0.00000000000000000000000000000000002452 138.0
MMD2_k127_1361279_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.0000000000000000000000000000000006959 133.0
MMD2_k127_1361279_1 Psort location Extracellular, score - - - 0.000638 53.0
MMD2_k127_1370088_0 nucleotide metabolic process - - - 0.0000000000000000000000003882 115.0
MMD2_k127_1370088_1 response to heat - - - 0.0000000000003074 74.0
MMD2_k127_1372049_0 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002025 207.0
MMD2_k127_1372049_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002143 201.0
MMD2_k127_1372049_10 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000002557 74.0
MMD2_k127_1372049_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000004444 206.0
MMD2_k127_1372049_3 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000002547 190.0
MMD2_k127_1372049_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000003656 184.0
MMD2_k127_1372049_5 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000001457 145.0
MMD2_k127_1372049_6 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000009913 122.0
MMD2_k127_1372049_7 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000004269 122.0
MMD2_k127_1372049_8 ribosomal protein S14 K02954 - - 0.000000000000000004259 89.0
MMD2_k127_1372049_9 Ribosomal L29 protein K02904 - - 0.00000000000008845 77.0
MMD2_k127_1388689_0 Beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000007743 209.0
MMD2_k127_1406186_0 aminopeptidase activity K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 505.0
MMD2_k127_1406186_1 parallel beta-helix repeat (two copies) - - - 0.000001201 61.0
MMD2_k127_1414784_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 321.0
MMD2_k127_1414784_1 PKD domain - - - 0.000005596 59.0
MMD2_k127_1428461_0 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - 0.00000000005313 76.0
MMD2_k127_1430643_0 TIGRFAM hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000002305 232.0
MMD2_k127_1430643_1 Transcriptional regulator K07722 - - 0.00000000000000000000000000000002004 132.0
MMD2_k127_1430643_2 PKD domain containing protein - - - 0.00000000000003963 87.0
MMD2_k127_1446941_0 amine dehydrogenase activity K20276 - - 0.000000000003041 79.0
MMD2_k127_1450394_0 Bacterial Ig-like domain (group 3) K20276 - - 0.000000000000000000000000000000006297 149.0
MMD2_k127_1455910_0 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000002563 169.0
MMD2_k127_1455910_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000002301 130.0
MMD2_k127_1455910_2 domain, Protein - - - 0.0000000000000000009032 90.0
MMD2_k127_1456136_0 HemY domain protein - - - 0.00000000000000000000000000000000000000000003578 186.0
MMD2_k127_1465491_0 Hemolysin-type calcium-binding - - - 0.000000000000000000000000000000004148 149.0
MMD2_k127_1465491_1 flavin reductase - - - 0.00000000000000000000000000002047 127.0
MMD2_k127_1465491_2 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.00000000000000000000244 109.0
MMD2_k127_1465491_3 Rubrerythrin - - - 0.00007398 52.0
MMD2_k127_1468505_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 429.0
MMD2_k127_148826_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 486.0
MMD2_k127_148826_1 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000000000000002942 135.0
MMD2_k127_1488813_0 COG1520 FOG WD40-like repeat - - - 0.00000000000000000000000000000000008748 151.0
MMD2_k127_1488813_1 WD domain, G-beta repeat - - - 0.00000000004031 74.0
MMD2_k127_149085_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 3.96e-314 994.0
MMD2_k127_149085_1 Alanine-glyoxylate amino-transferase K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 394.0
MMD2_k127_149085_2 Belongs to the glycosyl hydrolase 30 family K01201 - 3.2.1.45 0.0007135 51.0
MMD2_k127_1501485_0 - - - - 0.000000000000000000000000001236 131.0
MMD2_k127_1501485_1 PKD domain - - - 0.00000008123 65.0
MMD2_k127_1505652_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000002232 145.0
MMD2_k127_1505652_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000002674 145.0
MMD2_k127_1505652_2 TIGRFAM adenylyl cyclase CyaB K05873 GO:0003674,GO:0003824,GO:0004016,GO:0009975,GO:0016829,GO:0016849 4.6.1.1 0.000000000000000000000000000000002378 136.0
MMD2_k127_1505652_3 4Fe-4S dicluster domain - - - 0.00001653 53.0
MMD2_k127_15151_0 Rhodanese Homology Domain K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000002283 232.0
MMD2_k127_15151_1 PFAM UBA THIF-type NAD FAD binding protein - - - 0.0000000000000000000000000000000000000000002083 170.0
MMD2_k127_15151_2 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex - - - 0.000000000001108 83.0
MMD2_k127_1515615_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005635 283.0
MMD2_k127_1515615_1 protein histidine kinase activity - - - 0.00000000000000000000379 96.0
MMD2_k127_1515615_2 Pfam Response regulator receiver - - - 0.0000000000000000005384 92.0
MMD2_k127_1515615_3 SMART Elongator protein 3 MiaB NifB K15865 - 2.8.4.5 0.0000000003193 64.0
MMD2_k127_1525772_0 Low-density lipoprotein-receptor YWTD domain - - - 0.00000002621 66.0
MMD2_k127_1540507_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 356.0
MMD2_k127_1540507_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000007694 157.0
MMD2_k127_1540507_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.00000000000000000000000000000000000001784 151.0
MMD2_k127_1540507_3 Trm112p-like protein - - - 0.0000000000000002518 84.0
MMD2_k127_1568566_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000853 424.0
MMD2_k127_1568566_1 PFAM Cytochrome c assembly protein K02195 - - 0.00000000000004392 76.0
MMD2_k127_1568566_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00001312 54.0
MMD2_k127_1575260_0 transcription activator, effector binding - - - 0.000000000000000000000000000000000000000002204 162.0
MMD2_k127_1575260_1 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000000495 149.0
MMD2_k127_158110_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000001863 248.0
MMD2_k127_158110_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a - - - 0.000000000000000000000000000000000009925 150.0
MMD2_k127_1586708_0 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000042 295.0
MMD2_k127_1586708_1 Beta propeller domain - - - 0.00000000000000000000000000000000000000000000000000000000003993 233.0
MMD2_k127_1586708_2 Protein of unknown function (DUF531) K09725 - - 0.000000000000000000000000000000000000000000000001577 181.0
MMD2_k127_1591223_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 399.0
MMD2_k127_1591223_1 membrane transporter protein K07090 - - 0.000000000000512 79.0
MMD2_k127_1591223_2 cytochrome c biogenesis protein - - - 0.00008658 49.0
MMD2_k127_1601412_0 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000001682 251.0
MMD2_k127_1601412_1 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.0000000000000000000000000000000000000000003223 168.0
MMD2_k127_1601412_2 Mut7-C RNAse domain K09122 - - 0.000000000000000000000006699 111.0
MMD2_k127_1601412_3 Domain of unknown function DUF11 - - - 0.000004939 59.0
MMD2_k127_1615970_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000007183 175.0
MMD2_k127_1615970_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000006595 136.0
MMD2_k127_1615970_2 CAAX protease self-immunity K07052 - - 0.000000000000000000000000102 121.0
MMD2_k127_1615970_3 Uncharacterised protein family (UPF0147) K09721 - - 0.000000000000000000008461 99.0
MMD2_k127_1618462_0 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 369.0
MMD2_k127_1618462_1 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000000624 64.0
MMD2_k127_1627520_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001304 246.0
MMD2_k127_1627520_1 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000007242 190.0
MMD2_k127_1627520_2 PFAM amino acid-binding ACT domain protein - - - 0.000000004767 65.0
MMD2_k127_1630189_0 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001237 277.0
MMD2_k127_1630189_1 ATP cone domain - - - 0.00000000005532 68.0
MMD2_k127_1630189_2 response to heat - - - 0.0001178 55.0
MMD2_k127_1639748_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 364.0
MMD2_k127_1639748_1 SMART ATPase, AAA type, core K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001398 261.0
MMD2_k127_1639748_2 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000002132 230.0
MMD2_k127_1639748_3 TPR Domain containing protein - - - 0.0000000000000000000000000000000000000000000000004295 185.0
MMD2_k127_1639748_4 - - - - 0.00000000000000000000000000000000007198 141.0
MMD2_k127_1639748_5 alpha-L-arabinofuranosidase - - - 0.0000000000000000000000000000000003416 153.0
MMD2_k127_1639748_6 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000004216 85.0
MMD2_k127_1639748_7 VIT family - - - 0.00000000000006313 82.0
MMD2_k127_1639748_8 peptidase activity, acting on L-amino acid peptides K13735,K20276,K21449 - - 0.000000003087 68.0
MMD2_k127_1641880_0 PKD domain - - - 0.0000000000000000000000000000000000005487 158.0
MMD2_k127_1643385_0 Aminotransferase class-III K00823 - 2.6.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 469.0
MMD2_k127_1643385_1 domain, Protein - - - 0.000000000000000314 90.0
MMD2_k127_1650099_0 Hydantoinaseoxoprolinase domain protein K01473 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001024 286.0
MMD2_k127_1653957_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 323.0
MMD2_k127_1653957_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000005577 159.0
MMD2_k127_1654008_0 DOMON domain-containing protein - - - 0.0000000000000004388 94.0
MMD2_k127_1654008_1 methyltransferase activity - - - 0.00001082 60.0
MMD2_k127_1659601_0 CARDB - - - 0.000001296 61.0
MMD2_k127_1662979_0 Multicopper K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 616.0
MMD2_k127_1672959_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000009899 216.0
MMD2_k127_1672959_1 Cupin domain - - - 0.000000000000000000000003372 108.0
MMD2_k127_1672959_2 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000001758 66.0
MMD2_k127_1673420_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 338.0
MMD2_k127_1673420_1 myosin light chain kinase activity K12567 - 2.7.11.1 0.000000000000000000000000000000000000000001535 182.0
MMD2_k127_1673420_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000001133 74.0
MMD2_k127_1678676_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003959 351.0
MMD2_k127_1678676_1 Bacterial Ig-like domain (group 3) K20276 - - 0.00000000000001163 89.0
MMD2_k127_1678676_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000888 71.0
MMD2_k127_1678676_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000007216 63.0
MMD2_k127_1681207_0 TIGRFAM NiFe hydrogenase maturation protein HypF K04656 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 370.0
MMD2_k127_1681207_1 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 331.0
MMD2_k127_1681207_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000127 85.0
MMD2_k127_1681207_3 TIGRFAM hydrogenase assembly chaperone hypC hupF K04653 - - 0.000000000000001011 79.0
MMD2_k127_1686318_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007686 469.0
MMD2_k127_1686318_1 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 388.0
MMD2_k127_1686318_2 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 313.0
MMD2_k127_1686318_3 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001181 261.0
MMD2_k127_1686318_4 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000005084 197.0
MMD2_k127_1693808_0 FG-GAP repeat - - - 0.000000000000000000000000000000003565 151.0
MMD2_k127_1693808_1 metallopeptidase activity - - - 0.0000000001699 74.0
MMD2_k127_1693808_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000007685 65.0
MMD2_k127_1693808_3 N-Acetylmuramoyl-L-alanine amidase - - - 0.000317 53.0
MMD2_k127_1695529_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 451.0
MMD2_k127_1695529_1 PFAM HhH-GPD K07457 - - 0.00000000000000000000000000000000000000000000000000000000003486 217.0
MMD2_k127_1695529_2 KaiC - - - 0.0000000002398 70.0
MMD2_k127_1695583_0 proteolysis K03665 - - 0.00000000003592 73.0
MMD2_k127_1695583_1 PFAM Ubiquitin-conjugating - - - 0.000001734 56.0
MMD2_k127_1695583_2 Tubulin like - - - 0.0001244 55.0
MMD2_k127_1695583_3 protein conserved in archaea K09723 - - 0.0009869 44.0
MMD2_k127_1698932_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1215.0
MMD2_k127_1698932_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 472.0
MMD2_k127_1698932_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 409.0
MMD2_k127_1698932_3 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 - - 0.0000000000000000001386 92.0
MMD2_k127_1698932_4 Participates in transcription termination K02600 - - 0.000000000005334 71.0
MMD2_k127_170279_0 Hemolysin-type calcium-binding - - - 0.0000000000001084 85.0
MMD2_k127_1704206_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.866e-207 661.0
MMD2_k127_1704206_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 593.0
MMD2_k127_1708174_0 S-layer homology domain - - - 0.00000000000000000000000000000000000000000000000000000003699 226.0
MMD2_k127_1708174_1 Protein of unknown function (DUF402) K09145 - - 0.0000000000000038 83.0
MMD2_k127_1708174_2 cellulase activity K01795,K20276 - 5.1.3.37 0.0003293 49.0
MMD2_k127_1722408_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000002387 245.0
MMD2_k127_1722408_1 AAA domain K06873 - - 0.00000000000000000000000003212 126.0
MMD2_k127_1722408_2 FeoA K03709 - - 0.0000000000000000000001593 106.0
MMD2_k127_1722408_3 oligopeptide transporter, OPT family - - - 0.0000000000008589 82.0
MMD2_k127_1758215_0 COG5016 Pyruvate oxaloacetate carboxyltransferase K01960 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008631 534.0
MMD2_k127_1758215_1 Biotin-requiring enzyme - - - 0.00000000000000007069 87.0
MMD2_k127_1758215_2 PFAM carboxyl transferase K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 0.000000151 52.0
MMD2_k127_1759754_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000002535 87.0
MMD2_k127_1759754_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000001598 64.0
MMD2_k127_1761733_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.132e-250 804.0
MMD2_k127_1761733_1 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 460.0
MMD2_k127_1761733_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 368.0
MMD2_k127_1761733_3 Cation efflux family K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003925 259.0
MMD2_k127_1761733_4 Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000002923 169.0
MMD2_k127_1761733_5 PFAM CoA-binding domain protein - - - 0.0000000000000000000000000000000000000001356 168.0
MMD2_k127_1761733_6 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K07023 - 2.3.1.57 0.0000000000000000000000003362 112.0
MMD2_k127_1761733_7 TPR-like protein K03353 GO:0000151,GO:0000152,GO:0000228,GO:0000775,GO:0000785,GO:0000790,GO:0000792,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0005694,GO:0005720,GO:0005721,GO:0005737,GO:0005829,GO:0006275,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008156,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009896,GO:0009987,GO:0010498,GO:0010556,GO:0010558,GO:0010564,GO:0010605,GO:0010638,GO:0010965,GO:0016567,GO:0019219,GO:0019222,GO:0019538,GO:0019941,GO:0030071,GO:0030163,GO:0030174,GO:0031145,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031331,GO:0031461,GO:0031618,GO:0031974,GO:0031981,GO:0032270,GO:0032297,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044454,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0060255,GO:0062033,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0080090,GO:0090068,GO:0090329,GO:0098687,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2000104,GO:2000112,GO:2000113,GO:2001252 - 0.0004564 50.0
MMD2_k127_1785933_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 304.0
MMD2_k127_1785933_1 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.0000000000000000000000000000009588 141.0
MMD2_k127_1785933_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00001367 58.0
MMD2_k127_1785933_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0001897 55.0
MMD2_k127_1798667_0 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.0000000000000000003253 97.0
MMD2_k127_1798667_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000006789 95.0
MMD2_k127_1798667_2 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.00000000000000007963 83.0
MMD2_k127_1798667_3 - - - - 0.00000004046 63.0
MMD2_k127_1840788_0 Fe-S protein PflX, homolog of pyruvate formate lyase activating K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002641 274.0
MMD2_k127_1840788_1 Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate K06989 - 1.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000001155 244.0
MMD2_k127_1840788_2 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000007212 132.0
MMD2_k127_1840942_0 COG0608 Single-stranded DNA-specific exonuclease K07463 - - 0.0000000000000000000008614 99.0
MMD2_k127_1840942_1 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00000001774 67.0
MMD2_k127_1841337_0 Mo-co oxidoreductase dimerisation domain - - - 0.0000000000000000000000000000000000000002296 162.0
MMD2_k127_1841337_1 Bacterial transcription activator, effector binding domain - - - 0.000001985 59.0
MMD2_k127_1842769_0 FecR protein - - - 0.0000003119 59.0
MMD2_k127_1844416_0 cellulose binding - - - 0.0000000000000000000000000000000003972 154.0
MMD2_k127_1844416_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000001597 126.0
MMD2_k127_1844416_2 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000006719 79.0
MMD2_k127_1844416_3 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000008363 87.0
MMD2_k127_1844416_4 Integrin alpha (beta-propellor repeats). - - - 0.00004368 58.0
MMD2_k127_1847892_0 TPR Domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000005831 228.0
MMD2_k127_1847892_1 Roadblock LC7 family protein K07131 - - 0.00000000000006872 76.0
MMD2_k127_1857529_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000002125 151.0
MMD2_k127_1857529_1 alginic acid biosynthetic process - - - 0.000006875 59.0
MMD2_k127_185909_0 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009088 332.0
MMD2_k127_185909_1 ASCH - - - 0.0000000000000000000000000000000124 138.0
MMD2_k127_1861962_0 Large extracellular alpha-helical protein K06894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000427 424.0
MMD2_k127_1861962_1 cellulase activity K01083,K01224,K07004,K07156 - 3.1.3.8,3.2.1.89 0.000000008472 69.0
MMD2_k127_1861962_2 acetyltransferase K00619 - 2.3.1.1 0.0005655 50.0
MMD2_k127_1870740_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.00000000000000000000000000000000000000627 164.0
MMD2_k127_1870740_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000001124 155.0
MMD2_k127_1876634_0 AIR synthase related protein domain protein K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 415.0
MMD2_k127_1876634_1 PFAM Transketolase central region K00162 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000877 397.0
MMD2_k127_1876634_2 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 369.0
MMD2_k127_1876634_3 pyridoxamine 5'-phosphate K07005 - - 0.000000000000000000000001799 108.0
MMD2_k127_1876634_4 cell redox homeostasis - - - 0.00000000000000000003964 93.0
MMD2_k127_1876634_5 Protein of unknown function (DUF1059) - - - 0.00006615 51.0
MMD2_k127_188408_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009196 394.0
MMD2_k127_188408_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 389.0
MMD2_k127_188408_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000004815 186.0
MMD2_k127_1884457_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008674 286.0
MMD2_k127_1884457_1 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000001899 270.0
MMD2_k127_1902890_0 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 466.0
MMD2_k127_1902890_1 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000448 248.0
MMD2_k127_1902890_2 Protein of unknown function DUF47 K07220 - - 0.000000000000000000000000000000000000000000003981 172.0
MMD2_k127_1902890_3 phosphate K02040 GO:0003674,GO:0005488,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015698,GO:0042301,GO:0043167,GO:0043168,GO:0051179,GO:0051234 - 0.000000000000000000000000000000000000004804 159.0
MMD2_k127_1902890_4 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000551 126.0
MMD2_k127_1911896_0 type II secretion system protein K07333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 321.0
MMD2_k127_1935061_0 metallopeptidase activity - - - 0.000007062 60.0
MMD2_k127_1935061_1 Haemolysin-type calcium-binding repeat (2 copies) K01406 - 3.4.24.40 0.000219 53.0
MMD2_k127_1941283_0 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 418.0
MMD2_k127_1941283_1 - - - - 0.000000000000000000000000000000000000000000004787 184.0
MMD2_k127_1941283_2 Protein conserved in bacteria - - - 0.00000000000000000000000000000006757 131.0
MMD2_k127_1941283_3 Dodecin K09165 - - 0.000000000000002859 78.0
MMD2_k127_1941283_4 - - - - 0.0007364 48.0
MMD2_k127_1942573_0 cell redox homeostasis K02199 - - 0.0000000000000258 87.0
MMD2_k127_1952689_0 MCM OB domain K10726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 620.0
MMD2_k127_1952689_1 amino acid activation for nonribosomal peptide biosynthetic process K06045 - 4.2.1.129,5.4.99.17 0.000000005574 67.0
MMD2_k127_1965140_0 - - - - 0.000000000004109 80.0
MMD2_k127_1965148_0 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 309.0
MMD2_k127_1965148_1 Subtilase family - - - 0.000000000000000003762 88.0
MMD2_k127_1968676_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009515 525.0
MMD2_k127_1968676_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005954 461.0
MMD2_k127_1968676_2 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759,K22503 - 6.1.1.12,6.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 447.0
MMD2_k127_1968676_3 - - - - 0.00000000000001208 78.0
MMD2_k127_1968676_4 - - - - 0.000001749 55.0
MMD2_k127_1968676_5 Oxidoreductase molybdopterin binding domain K00387 - 1.8.3.1 0.0002177 51.0
MMD2_k127_1974669_0 Transcription factor zinc-finger - - - 0.0000002311 61.0
MMD2_k127_2001359_0 Belongs to the N(4) N(6)-methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 292.0
MMD2_k127_2001359_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000002155 144.0
MMD2_k127_2008320_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 7.479e-199 627.0
MMD2_k127_2008320_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009941 294.0
MMD2_k127_2042302_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000006769 165.0
MMD2_k127_2042302_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000001071 148.0
MMD2_k127_2042302_2 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes K08321,K11645 - 2.3.1.245,4.1.2.13 0.00000000000004475 73.0
MMD2_k127_2044795_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007279 379.0
MMD2_k127_2044795_1 snRNP Sm proteins K04796 - - 0.0000000000000005803 88.0
MMD2_k127_2044795_2 transferase hexapeptide repeat containing protein K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000001712 53.0
MMD2_k127_2061346_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 361.0
MMD2_k127_2070635_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 317.0
MMD2_k127_2070635_1 dTDP-glucose pyrophosphorylase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000007893 211.0
MMD2_k127_208598_0 nucleotidyltransferase activity K07076 - - 0.00000000000000000001153 99.0
MMD2_k127_208598_1 DNA-sulfur modification-associated - - - 0.0000009461 61.0
MMD2_k127_208598_2 - - - - 0.000001963 51.0
MMD2_k127_208598_3 HEPN domain K09132 - - 0.00002547 53.0
MMD2_k127_2088037_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1085.0
MMD2_k127_2088037_1 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 542.0
MMD2_k127_2088037_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001906 274.0
MMD2_k127_2088037_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000476 216.0
MMD2_k127_2088037_4 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000002251 186.0
MMD2_k127_2088037_5 4Fe-4S binding domain - - - 0.00000000002352 66.0
MMD2_k127_2088037_6 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000128 56.0
MMD2_k127_2101998_0 regulator of chromosome condensation, RCC1 - - - 0.0000000000002747 84.0
MMD2_k127_2132488_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 588.0
MMD2_k127_2132488_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 304.0
MMD2_k127_2135647_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.384e-203 649.0
MMD2_k127_2135647_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 489.0
MMD2_k127_2135647_2 L-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004961 367.0
MMD2_k127_2135647_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000003107 194.0
MMD2_k127_2135647_4 Multidrug efflux transporter, MFS family protein - - - 0.00000000000000001517 95.0
MMD2_k127_2136758_0 BioY family K03523 - - 0.000000000000000000000000000000000000000000000000009356 190.0
MMD2_k127_2136758_1 - - - - 0.00000000000000000000000000000001983 138.0
MMD2_k127_2136758_2 Transcriptional regulators - - - 0.0000000002076 70.0
MMD2_k127_2136758_3 - - - - 0.0004131 51.0
MMD2_k127_2141252_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006636 636.0
MMD2_k127_2145147_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 349.0
MMD2_k127_2145147_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 343.0
MMD2_k127_2145147_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 298.0
MMD2_k127_2145147_3 PAC2 family K06869 - - 0.000000000000000000000000000000000000000002399 165.0
MMD2_k127_2148771_0 membrane-associated protein domain - - - 0.000000000000001866 89.0
MMD2_k127_2148771_1 PFAM Cytochrome C biogenesis protein transmembrane region - - - 0.000002126 54.0
MMD2_k127_2149759_0 Belongs to the peptidase S8 family - - - 0.00000001631 68.0
MMD2_k127_2154257_0 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001488 250.0
MMD2_k127_2154257_1 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000005531 209.0
MMD2_k127_2154257_2 RNA polymerase subunit 9 K03057 - - 0.0000000000000000000000000009925 116.0
MMD2_k127_2155309_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 369.0
MMD2_k127_2155309_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000973 220.0
MMD2_k127_2155309_2 Dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000001984 151.0
MMD2_k127_2155309_3 AIG2-like family - - - 0.0000000000005811 79.0
MMD2_k127_2161809_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000008837 209.0
MMD2_k127_2161809_1 oxidase subunit III K02299 - - 0.00000000000000000000000000000000001836 145.0
MMD2_k127_2162094_0 Bacterial Ig-like domain (group 3) K20276 - - 0.00000000000000000000003124 118.0
MMD2_k127_2162094_1 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.00000001541 69.0
MMD2_k127_2162094_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0001502 52.0
MMD2_k127_2172812_0 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000432 228.0
MMD2_k127_2172812_1 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000001757 118.0
MMD2_k127_2172812_2 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00001888 50.0
MMD2_k127_2174043_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009356 327.0
MMD2_k127_217525_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.000000000000000000000000000000000000000000000000000000002198 208.0
MMD2_k127_217525_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000002804 198.0
MMD2_k127_2179934_0 ADP-ribosylation factor family - - - 0.0000000000000000000000000000001036 131.0
MMD2_k127_2179934_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.00000000000000000003032 102.0
MMD2_k127_2179934_2 PFAM Roadblock LC7 family protein K07131 - - 0.000000000884 66.0
MMD2_k127_2179934_3 hydrocarbon binding protein (contains V4R domain) K07013 - - 0.00000001198 63.0
MMD2_k127_2180677_0 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 289.0
MMD2_k127_2180677_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000001508 65.0
MMD2_k127_2195091_0 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000000000000004051 139.0
MMD2_k127_2195091_1 Creatinase/Prolidase N-terminal domain - - - 0.00000000000000000000000000004659 119.0
MMD2_k127_2195091_2 Rieske-like [2Fe-2S] domain - - - 0.00000000000000000000000000007311 119.0
MMD2_k127_2195091_3 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000002564 115.0
MMD2_k127_2195091_4 Glutaredoxin - - - 0.00000000000000000000002166 103.0
MMD2_k127_2197397_0 FG-GAP repeat - - - 0.00000000003215 77.0
MMD2_k127_2199077_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 3.55e-221 699.0
MMD2_k127_2199077_1 Pirin K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 348.0
MMD2_k127_2199077_2 COG1064 Zn-dependent alcohol K12957 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 303.0
MMD2_k127_2199077_3 COG0328 Ribonuclease HI K03469 - 3.1.26.4 0.0000000000000000000000007098 110.0
MMD2_k127_2199077_4 Domain of unknown function K20276 - - 0.000000000000000002242 102.0
MMD2_k127_2199077_5 Dystroglycan-type cadherin-like domains. - - - 0.000000000000000007233 98.0
MMD2_k127_2199077_6 Fibronectin type 3 domain - - - 0.0000001212 64.0
MMD2_k127_2199077_7 TIGRFAM delta-1-pyrroline-5-carboxylate dehydrogenase, group 1 K00294,K13821 - 1.2.1.88,1.5.5.2 0.0001764 46.0
MMD2_k127_2200890_0 PFAM ABC transporter related K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 349.0
MMD2_k127_2200890_1 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001147 285.0
MMD2_k127_2200890_2 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000001424 147.0
MMD2_k127_2200890_3 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.0000000000000000000000001105 109.0
MMD2_k127_2202894_0 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 366.0
MMD2_k127_2202894_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000003798 228.0
MMD2_k127_2202894_2 poly-hydroxybutyrate biosynthetic process - - - 0.000003268 56.0
MMD2_k127_2204227_0 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 323.0
MMD2_k127_2204227_1 PFAM FecR protein K09800,K13735 - - 0.0000000000001723 85.0
MMD2_k127_2205735_0 HELICc2 K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 377.0
MMD2_k127_2205735_1 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000002828 216.0
MMD2_k127_2205735_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000000002593 192.0
MMD2_k127_2205735_3 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000007296 174.0
MMD2_k127_2205735_4 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000006451 109.0
MMD2_k127_2205735_5 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.000000000000000000000002264 114.0
MMD2_k127_2205735_6 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001491 88.0
MMD2_k127_2205735_7 Belongs to the PdaD family K02626 - 4.1.1.19 0.00000000000436 72.0
MMD2_k127_2205735_8 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000004185 62.0
MMD2_k127_2214572_0 DNA polymerase type-B family K02319 - 2.7.7.7 6.235e-216 689.0
MMD2_k127_2244157_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000001828 196.0
MMD2_k127_2244157_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.00000000000000000000000000000000000001133 167.0
MMD2_k127_2244157_2 TPM domain K06872 - - 0.00000000000003938 82.0
MMD2_k127_2247730_0 PFAM CoA-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001379 290.0
MMD2_k127_2247730_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000005505 225.0
MMD2_k127_2247730_2 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000006237 172.0
MMD2_k127_2247730_3 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000001962 147.0
MMD2_k127_2260877_0 TIGRFAM Outer membrane protein K13735,K20276 - - 0.00000000000000000000000004585 126.0
MMD2_k127_2284435_0 Archaeal holliday junction resolvase (hjc) - - - 0.00000000000000000000000000000000000000000003952 166.0
MMD2_k127_2284435_1 PAC2 family K06869 - - 0.00000000000000000000000006776 120.0
MMD2_k127_2288800_0 Cell division protein 48, CDC48, domain 2 K13525 - - 3.411e-269 848.0
MMD2_k127_2288800_1 ABC transporter K00400,K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 319.0
MMD2_k127_2288800_2 Cobalt transport protein K16785 - - 0.000000000000000000000000000000000000000004249 173.0
MMD2_k127_2288800_3 PRC-barrel domain - - - 0.0000000000000000000000000006532 114.0
MMD2_k127_2288800_4 Glycosyl transferases group 1 - - - 0.0004146 52.0
MMD2_k127_2290047_0 ATPase, AAA superfamily K06921 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000137 294.0
MMD2_k127_2290047_1 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000003134 145.0
MMD2_k127_2290971_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000001183 121.0
MMD2_k127_2290971_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000008438 60.0
MMD2_k127_2299091_0 PFAM Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006021 267.0
MMD2_k127_2301104_0 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000999 96.0
MMD2_k127_2301104_1 regulator of chromosome condensation, RCC1 K20276 - - 0.000000000000001196 92.0
MMD2_k127_2307431_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 383.0
MMD2_k127_2307431_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 344.0
MMD2_k127_2307431_2 Subtilase family K17734 - - 0.00000000000000000000000000000000001618 151.0
MMD2_k127_2307431_3 cheY-homologous receiver domain K03413 - - 0.00000000000004318 84.0
MMD2_k127_2307431_4 Sugar-specific transcriptional regulator TrmB - - - 0.0000008077 60.0
MMD2_k127_2310490_0 Double zinc ribbon - - - 0.0000000000003326 85.0
MMD2_k127_2338022_0 HWE histidine kinase - - - 0.00000000000000000000006306 114.0
MMD2_k127_2346169_0 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007597 361.0
MMD2_k127_2346169_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000457 246.0
MMD2_k127_2346169_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000004451 249.0
MMD2_k127_2346169_3 Phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000003586 189.0
MMD2_k127_2346169_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000482 201.0
MMD2_k127_2346169_5 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000000000000000000000000003742 143.0
MMD2_k127_2346169_6 von Willebrand factor, type A K11912 - 2.7.11.1 0.000000000000000000000000000000001263 146.0
MMD2_k127_2346169_7 Von willebrand factor, type a - - - 0.0000000000000000000004952 109.0
MMD2_k127_2358989_0 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000003528 141.0
MMD2_k127_2358989_1 Sulfurtransferase TusA - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000003999 89.0
MMD2_k127_2358989_2 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000000005858 96.0
MMD2_k127_2358989_3 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.0000000000006461 70.0
MMD2_k127_2358989_4 reverse transcriptase K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000135 81.0
MMD2_k127_2358989_5 OsmC-like protein - - - 0.00000009658 61.0
MMD2_k127_2359059_0 Bifunctional pyrimidine biosynthesis protein (PyrABCN) K01954,K11541 GO:0000050,GO:0003674,GO:0003824,GO:0003922,GO:0004070,GO:0004087,GO:0004088,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006139,GO:0006142,GO:0006206,GO:0006207,GO:0006520,GO:0006525,GO:0006526,GO:0006541,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009892,GO:0009987,GO:0016020,GO:0016021,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0016787,GO:0016810,GO:0016812,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019219,GO:0019222,GO:0019627,GO:0019752,GO:0019856,GO:0031224,GO:0031323,GO:0031324,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044425,GO:0044444,GO:0044464,GO:0045934,GO:0045984,GO:0046112,GO:0046394,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0055086,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071941,GO:0072527,GO:0072528,GO:0080090,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.2,6.3.5.5 7.553e-294 925.0
MMD2_k127_2359059_1 MMPL family K06994 - - 0.0000000223 66.0
MMD2_k127_2362370_0 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 488.0
MMD2_k127_2362370_1 DNA polymerase type-B family K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000005089 200.0
MMD2_k127_2368207_0 Acetyltransferase (GNAT) family - - - 0.0000000000000001387 92.0
MMD2_k127_2368207_1 regulator of chromosome condensation, RCC1 - - - 0.00000000006913 76.0
MMD2_k127_2368207_2 - - - - 0.0007996 51.0
MMD2_k127_2373747_0 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 377.0
MMD2_k127_2373747_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 334.0
MMD2_k127_2373747_2 Belongs to the ompA family K20276 - - 0.0000000000000000000000000003941 133.0
MMD2_k127_2373747_3 Domain of unknown function - - - 0.00000000000000000000000004791 126.0
MMD2_k127_2373747_4 Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase - - - 0.000000000005315 79.0
MMD2_k127_2373747_5 SpoVT / AbrB like domain - - - 0.00000000005845 66.0
MMD2_k127_2375350_0 Methyl-viologen-reducing hydrogenase, delta subunit K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 481.0
MMD2_k127_2375350_1 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001891 290.0
MMD2_k127_2375350_2 HEPN domain - - - 0.000000000000000000000001403 109.0
MMD2_k127_2375350_3 DNA polymerase beta - - - 0.000000000000000000000002957 112.0
MMD2_k127_2375350_4 CARDB - - - 0.0002439 53.0
MMD2_k127_2376413_0 glycoside hydrolase, family - - - 1.279e-277 939.0
MMD2_k127_2376413_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000039 409.0
MMD2_k127_2376413_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000009356 207.0
MMD2_k127_2376413_3 D,D-heptose 1,7-bisphosphate phosphatase K03273,K15669 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 2.7.7.71,3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000002138 168.0
MMD2_k127_2376413_4 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.0002475 49.0
MMD2_k127_2388733_0 Belongs to the HypD family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003989 271.0
MMD2_k127_2388733_1 Domain of unknown function (DUF4382) - - - 0.000000000000000007994 97.0
MMD2_k127_2388733_2 Domain of unknown function (DUF4382) - - - 0.0000000002226 73.0
MMD2_k127_2389482_0 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000008293 153.0
MMD2_k127_2389482_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000006042 135.0
MMD2_k127_2389482_2 Belongs to the UPF0248 family K09715 - - 0.00007869 51.0
MMD2_k127_2389640_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 367.0
MMD2_k127_2389640_1 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002426 246.0
MMD2_k127_2389640_2 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.0000000000000000000000000000000000000000003618 166.0
MMD2_k127_2389640_3 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000003357 162.0
MMD2_k127_2389640_4 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000004888 163.0
MMD2_k127_2389640_5 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000003044 151.0
MMD2_k127_2389803_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 298.0
MMD2_k127_2389803_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000003649 160.0
MMD2_k127_2389803_2 PRC-barrel domain - - - 0.0000000000000000001424 94.0
MMD2_k127_2389803_3 PFAM Xylose isomerase domain protein TIM barrel - - - 0.0000000002645 72.0
MMD2_k127_2389803_4 - - - - 0.000005002 50.0
MMD2_k127_2408716_0 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000001826 241.0
MMD2_k127_2408716_1 - - - - 0.00000000000000012 85.0
MMD2_k127_2429682_0 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000000000000001066 256.0
MMD2_k127_2433865_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 387.0
MMD2_k127_2433865_1 pfam abc1 K03688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 327.0
MMD2_k127_2433865_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001226 305.0
MMD2_k127_2433865_3 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000002333 168.0
MMD2_k127_2436676_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 370.0
MMD2_k127_2436676_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000732 196.0
MMD2_k127_2436676_2 ICC-like phosphoesterases K06953 - - 0.000000000000002537 82.0
MMD2_k127_2467751_0 Periplasmic copper-binding protein (NosD) K07218 - - 0.0001208 55.0
MMD2_k127_2471288_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 434.0
MMD2_k127_2471288_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000007244 196.0
MMD2_k127_2471288_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.00000000000000000000000000000000000000000000000003917 185.0
MMD2_k127_2471288_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000000000000000000000000000004454 126.0
MMD2_k127_2473308_0 - - - - 0.0000000000000000346 96.0
MMD2_k127_2498100_0 Fungal trichothecene efflux pump (TRI12) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001065 275.0
MMD2_k127_2498100_1 - - - - 0.000000000000000000000000000000000000000000000000000000000002267 216.0
MMD2_k127_2498100_2 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000008184 168.0
MMD2_k127_2498100_3 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000001881 57.0
MMD2_k127_2510015_0 Phosphate uptake regulator, PhoU - - - 0.000000000000000000000000000000000000000000000000000000000000000000008484 247.0
MMD2_k127_2510015_1 protein conserved in archaea - - - 0.00000000008991 74.0
MMD2_k127_2510015_2 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0001665 45.0
MMD2_k127_2515357_0 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000167 272.0
MMD2_k127_2515357_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000004812 179.0
MMD2_k127_2515357_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000005734 164.0
MMD2_k127_2515357_3 Glycosyltransferase Family 4 K12995 - 2.4.1.348 0.0000000000000002852 91.0
MMD2_k127_2515357_4 TIGRFAM stage V sporulation protein B K06409 - - 0.00000008939 65.0
MMD2_k127_2515357_5 CAAX protease self-immunity K07052 - - 0.000005486 60.0
MMD2_k127_2515357_6 oxidoreductase At1g06690 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0009507,GO:0009526,GO:0009532,GO:0009534,GO:0009535,GO:0009536,GO:0009570,GO:0009579,GO:0009941,GO:0010287,GO:0016020,GO:0031967,GO:0031975,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0055035 - 0.0002416 44.0
MMD2_k127_2526814_0 transcriptional regulators - - - 0.000000000000000000002029 102.0
MMD2_k127_2526814_1 Carotenoid biosynthesis protein - - - 0.0004832 49.0
MMD2_k127_2526814_2 Rhodanese Homology Domain - - - 0.0006871 51.0
MMD2_k127_252960_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 1.217e-201 657.0
MMD2_k127_252960_1 Methyltransferase domain - - - 0.00000000000000000000000000000000008814 143.0
MMD2_k127_2531781_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 327.0
MMD2_k127_2531781_1 KEOPS complex Cgi121-like subunit K09119 - - 0.000000002045 67.0
MMD2_k127_2531781_2 S-layer protein - - - 0.000000007608 70.0
MMD2_k127_2535214_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.000000000000000000000000000000000000000000000000000000000000000000000001383 258.0
MMD2_k127_2535748_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006376 310.0
MMD2_k127_2535748_1 - - - - 0.000000000000000000000000000000001404 134.0
MMD2_k127_2535748_2 - - - - 0.000000000000000005049 91.0
MMD2_k127_2540311_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 306.0
MMD2_k127_2540311_1 - K06193 - - 0.0006972 44.0
MMD2_k127_2540831_0 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 362.0
MMD2_k127_2540831_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000003532 258.0
MMD2_k127_2540831_2 PFAM PKD domain containing protein - - - 0.000004552 54.0
MMD2_k127_2569429_0 Integrin alpha (beta-propellor repeats). - - - 0.000000000000000000000000000000002205 151.0
MMD2_k127_2571211_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 310.0
MMD2_k127_2571211_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 288.0
MMD2_k127_2571211_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000002325 246.0
MMD2_k127_2571211_3 binds to the 23S rRNA K02921 - - 0.000000000000000000062 93.0
MMD2_k127_2571211_4 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.00000002047 56.0
MMD2_k127_2572197_0 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 307.0
MMD2_k127_2572197_1 Amino acid kinase family K00928,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000004393 168.0
MMD2_k127_2572197_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000002936 148.0
MMD2_k127_2572197_3 TonB-dependent receptor K16089 - - 0.00001363 56.0
MMD2_k127_2572197_4 Glycosyl hydrolase family 48 - - - 0.0005042 54.0
MMD2_k127_2576889_0 Hep Hag repeat protein - - - 0.0000000000000007912 92.0
MMD2_k127_2587863_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008984 347.0
MMD2_k127_2587863_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0048037,GO:0051536,GO:0051540,GO:0055114 1.7.7.2 0.000000000000000000000000000000000000000000000000000000000003389 235.0
MMD2_k127_2587863_2 archaeal Zn-finger protein - - - 0.0000000000000000001181 96.0
MMD2_k127_2587863_3 Molybdopterin-guanine dinucleotide biosynthesis protein B K03753,K13818 - 2.7.7.77 0.000000000000002034 85.0
MMD2_k127_2587863_4 - - - - 0.0000000009315 62.0
MMD2_k127_2587863_5 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000005879 62.0
MMD2_k127_2587863_6 PFAM UspA domain protein - - - 0.0000003499 57.0
MMD2_k127_2590448_0 Toprim domain K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 395.0
MMD2_k127_2590448_1 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000001957 97.0
MMD2_k127_2590448_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000001646 89.0
MMD2_k127_2592911_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005878 266.0
MMD2_k127_2607659_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 555.0
MMD2_k127_2607659_1 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000001844 59.0
MMD2_k127_2607947_0 glycoside hydrolase, family - - - 0.00000000000000000000000000000000000001688 157.0
MMD2_k127_2607947_1 PFAM PKD domain containing protein - - - 0.0003267 46.0
MMD2_k127_2608243_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000006646 60.0
MMD2_k127_2608243_1 Fibronectin type III domain K12567 - 2.7.11.1 0.00002071 56.0
MMD2_k127_2628552_0 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 424.0
MMD2_k127_2628552_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.00000000000000000000000000000000000000005547 155.0
MMD2_k127_2628552_2 Serine aminopeptidase, S33 - - - 0.000000000008372 72.0
MMD2_k127_2630624_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 553.0
MMD2_k127_2630624_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000005551 198.0
MMD2_k127_2642023_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000164 297.0
MMD2_k127_2642023_1 SMART Parallel beta-helix repeat - - - 0.0004174 52.0
MMD2_k127_2650528_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001874 287.0
MMD2_k127_2650528_1 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002604 267.0
MMD2_k127_2650528_2 PFAM Ribosomal protein S27E K02978 - - 0.000000000000007913 76.0
MMD2_k127_2650528_3 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000001776 59.0
MMD2_k127_2657998_0 TIGRFAM conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 333.0
MMD2_k127_2657998_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.0000000000000000000000000000000000000000000000003716 203.0
MMD2_k127_2657998_2 Low-density lipoprotein-receptor YWTD domain - - - 0.00003138 56.0
MMD2_k127_2662736_0 Nitrate reductase gamma subunit K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000007915 154.0
MMD2_k127_2662736_1 Glycine cleavage system H protein K02437 - - 0.00000000000000000000000000000000000005115 149.0
MMD2_k127_2662736_2 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000003485 144.0
MMD2_k127_2662736_3 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000146 103.0
MMD2_k127_2675715_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 346.0
MMD2_k127_2675715_1 S-layer homology domain - - - 0.00000000000000001164 96.0
MMD2_k127_2731462_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003956 408.0
MMD2_k127_2731462_1 PFAM Na-Ca exchanger integrin-beta4 peptidase-like FG-GAP K20276 - - 0.0000000000000000000000000004944 130.0
MMD2_k127_2758782_0 4Fe-4S single cluster domain K07129 - - 0.0000000008801 60.0
MMD2_k127_2758782_1 Fungalysin metallopeptidase (M36) - - - 0.00005674 57.0
MMD2_k127_2758782_2 Zinc metalloprotease (Elastase) K01183 - 3.2.1.14 0.00005674 57.0
MMD2_k127_2763566_0 Membrane protein of unknown function DUF63 - - - 0.00000000000001422 84.0
MMD2_k127_2770328_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 1.272e-287 897.0
MMD2_k127_2770328_1 PFAM CoA-binding domain protein K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000007998 229.0
MMD2_k127_2770719_0 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000006004 69.0
MMD2_k127_277820_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000009347 153.0
MMD2_k127_2778991_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000002871 192.0
MMD2_k127_2780263_0 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000009183 140.0
MMD2_k127_2780263_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0001373 49.0
MMD2_k127_2780861_0 Protein of unknown function (DUF1698) - - - 0.00000000001196 77.0
MMD2_k127_2785498_0 amine dehydrogenase activity - - - 0.0000000000000000000000000001416 134.0
MMD2_k127_2793933_0 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 295.0
MMD2_k127_2793933_1 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 282.0
MMD2_k127_2793933_2 Predicted membrane protein (DUF2070) K08979 - - 0.00000000000000000000000000000000000000000000000000000267 215.0
MMD2_k127_2793933_3 B12 binding domain - - - 0.00000000000000000000000000001097 121.0
MMD2_k127_2793933_4 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.00000000000000000000000000001498 120.0
MMD2_k127_2803272_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005675 358.0
MMD2_k127_2803272_1 - - - - 0.00000000000000003963 93.0
MMD2_k127_2803272_2 Glycosyl transferase 4-like - - - 0.0000000173 62.0
MMD2_k127_281640_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000002029 216.0
MMD2_k127_2818693_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1046.0
MMD2_k127_2818693_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.996e-256 807.0
MMD2_k127_2818693_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 411.0
MMD2_k127_2818693_3 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 352.0
MMD2_k127_2818693_4 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003893 288.0
MMD2_k127_2818693_5 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000001864 197.0
MMD2_k127_2818693_6 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000001443 126.0
MMD2_k127_2826563_0 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004716 287.0
MMD2_k127_2826563_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000004497 199.0
MMD2_k127_2826563_2 Chromate resistance - - - 0.000000000000000000000000000000000000000000000001567 179.0
MMD2_k127_2826563_3 Papain family cysteine protease - - - 0.000000000000008495 84.0
MMD2_k127_2826563_4 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000000000555 79.0
MMD2_k127_2837625_0 peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000000000001692 213.0
MMD2_k127_2841475_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000001535 244.0
MMD2_k127_2841475_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.00000000000000000000000000008683 135.0
MMD2_k127_2860702_0 Type II/IV secretion system protein K07332 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 597.0
MMD2_k127_2860702_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000004476 246.0
MMD2_k127_2860702_2 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000004881 221.0
MMD2_k127_2860702_3 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000005138 205.0
MMD2_k127_2860702_4 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000176 134.0
MMD2_k127_2860702_5 Alpha-L-arabinofuranosidase C-terminal domain - - - 0.00000000000000000000000000008767 134.0
MMD2_k127_2860702_6 PFAM PKD domain containing protein - - - 0.00000000000006636 82.0
MMD2_k127_2861923_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 356.0
MMD2_k127_287367_0 Integrin alpha (beta-propellor repeats). - - - 0.00000000000004762 85.0
MMD2_k127_2891133_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003044 290.0
MMD2_k127_2891133_1 PKD domain - - - 0.0000000000001382 83.0
MMD2_k127_2891133_2 OmpA family - - - 0.00000000005673 75.0
MMD2_k127_2892294_0 PFAM FecR protein K20276 - - 0.0001418 55.0
MMD2_k127_2899998_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000005164 156.0
MMD2_k127_2899998_1 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000001411 87.0
MMD2_k127_2899998_2 6-phosphogluconolactonase activity - - - 0.00000000008848 74.0
MMD2_k127_2951020_0 OmpA family - - - 0.00000001261 67.0
MMD2_k127_295383_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000001785 125.0
MMD2_k127_295383_1 methyltransferase - - - 0.00000000000000000000004915 109.0
MMD2_k127_295383_2 proteolysis K03665 - - 0.000000000000000000009182 101.0
MMD2_k127_2965810_0 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions - - - 0.00000000000004175 73.0
MMD2_k127_2965810_1 Oxidoreductase molybdopterin binding domain K00387 - 1.8.3.1 0.000004923 53.0
MMD2_k127_2965810_2 helix_turn_helix ASNC type - - - 0.00003329 51.0
MMD2_k127_3004243_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 448.0
MMD2_k127_3039996_0 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 491.0
MMD2_k127_3039996_1 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006084 288.0
MMD2_k127_3039996_2 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.00001644 57.0
MMD2_k127_3043333_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000003588 83.0
MMD2_k127_3121666_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000945 196.0
MMD2_k127_3121666_1 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.0000000000000000000000000000000000000000004022 172.0
MMD2_k127_3173695_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000003211 93.0
MMD2_k127_3186780_0 Hydrogenase maturation protease K03605 - - 0.0000000000000000000001067 103.0
MMD2_k127_3186780_1 Hydrogenase maturation protease K03605 - - 0.00000000000001112 80.0
MMD2_k127_3186780_2 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000007852 57.0
MMD2_k127_3204890_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00000000000002143 87.0
MMD2_k127_3209398_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 425.0
MMD2_k127_3213050_0 gluconolactonase activity K01053,K01179,K07214,K12287 - 3.1.1.17,3.2.1.4 0.00002906 57.0
MMD2_k127_3213050_1 Belongs to the peptidase S8 family - - - 0.0003359 49.0
MMD2_k127_3218892_0 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000004295 159.0
MMD2_k127_3218892_1 Phosphoesterase - - - 0.000000000000000000000000000004017 124.0
MMD2_k127_3218892_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000895 115.0
MMD2_k127_3218892_3 Psort location Cytoplasmic, score - - - 0.0000000000000009213 87.0
MMD2_k127_3218892_4 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.00000000006882 73.0
MMD2_k127_3231873_0 Domain of unknown function DUF11 - - - 0.000001767 61.0
MMD2_k127_3238536_0 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 388.0
MMD2_k127_3244650_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000002101 163.0
MMD2_k127_325798_0 4-hydroxyphenylacetate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000059 555.0
MMD2_k127_325798_1 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000002588 196.0
MMD2_k127_325798_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000007527 118.0
MMD2_k127_325798_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000526 108.0
MMD2_k127_3258491_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006612 442.0
MMD2_k127_3258491_1 Fe-S cluster K04488 - - 0.00000000000000000000000000000000000000000000000002007 186.0
MMD2_k127_3259525_0 Papain family cysteine protease - - - 0.000000000001911 80.0
MMD2_k127_3279565_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000002469 213.0
MMD2_k127_3279565_1 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802 - 5.2.1.8 0.000000000000000000000000004213 126.0
MMD2_k127_3289961_0 COG1022 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 4.576e-310 975.0
MMD2_k127_3289961_1 PFAM Glucose-methanol-choline oxidoreductase, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 536.0
MMD2_k127_3289961_2 PFAM Polysaccharide pyruvyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 449.0
MMD2_k127_3289961_3 - - - - 0.00000000000000000000000000000000000002104 168.0
MMD2_k127_3298636_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004405 334.0
MMD2_k127_3298636_1 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 314.0
MMD2_k127_3298636_2 Fibronectin type III domain K12567 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000007599 232.0
MMD2_k127_3298636_3 PFAM Cobalt transport protein K16785 - - 0.00000000000000000000000000000000000001018 159.0
MMD2_k127_3298636_4 Fibronectin type III domain - - - 0.00000000000000000000000000000001443 134.0
MMD2_k127_3298636_5 Transcriptional regulator K07730 - - 0.00000000000000000000000000000005396 136.0
MMD2_k127_3298636_6 Periplasmic copper-binding protein (NosD) - - - 0.000000000000001076 91.0
MMD2_k127_3298636_7 PFAM Prenyltransferase squalene oxidase - - - 0.0002024 51.0
MMD2_k127_3304632_0 Bacterial Ig-like domain (group 3) - - - 0.000001763 61.0
MMD2_k127_3306810_0 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000009532 137.0
MMD2_k127_3306810_1 PFAM glycoside hydrolase, family 10 K01181 - 3.2.1.8 0.000018 56.0
MMD2_k127_331117_0 Bacterial Ig-like domain (group 3) K20276 - - 0.00000000000000000000002873 117.0
MMD2_k127_3316535_0 Domain of unknown function (DUF814) - - - 0.000000000000000000000000000007098 129.0
MMD2_k127_3316535_1 thymidylate kinase K00943 - 2.7.4.9 0.00000000000000000000001696 107.0
MMD2_k127_3318405_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 443.0
MMD2_k127_3318405_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 318.0
MMD2_k127_3318405_2 Helix-hairpin-helix motif K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000002825 231.0
MMD2_k127_3318405_3 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000128 238.0
MMD2_k127_3318405_4 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000001486 179.0
MMD2_k127_3318405_5 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.0000000000000000000000001487 109.0
MMD2_k127_3318405_6 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000000000000001443 85.0
MMD2_k127_3319122_0 Subtilase family K17734 - - 0.00000000000000000000000000000000000000000000000000000000205 229.0
MMD2_k127_3326063_0 Bacterial periplasmic substrate-binding proteins K02030 - - 0.000000003784 70.0
MMD2_k127_3326063_1 RHS Repeat - - - 0.0000000577 66.0
MMD2_k127_3326063_2 FlgD Ig-like domain - - - 0.0001012 55.0
MMD2_k127_3329158_0 DnaB-like helicase C terminal domain - - - 0.0000000000000000000000000000000000000000000000000000004864 202.0
MMD2_k127_3329158_1 SMART Parallel beta-helix repeat - - - 0.000002056 60.0
MMD2_k127_3330847_0 SMART zinc finger, CDGSH-type domain protein - - - 0.000000000000000000000000000000000000000000000000000000009912 203.0
MMD2_k127_3330847_1 Cupin domain protein - - - 0.000000000000000000000000000000000004276 141.0
MMD2_k127_3330847_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000002672 135.0
MMD2_k127_3330847_3 HAD-superfamily hydrolase, subfamily IB, PSPase-like K08966 - 3.1.3.87 0.00000000000000000000000000003689 126.0
MMD2_k127_3330847_4 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000001098 119.0
MMD2_k127_3330847_5 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.0000000000000000826 87.0
MMD2_k127_3330847_6 Domain of unknown function (DU1801) - - - 0.000000000001748 73.0
MMD2_k127_3337160_0 Protein of unknown function (DUF3795) - - - 0.00000000000000000000001569 105.0
MMD2_k127_3337160_1 amine dehydrogenase activity - - - 0.000000000005329 78.0
MMD2_k127_3342736_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 389.0
MMD2_k127_3342736_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 316.0
MMD2_k127_3342736_2 Methyltransferase type 11 - - - 0.0000000000000000006915 96.0
MMD2_k127_3343529_0 Peptidase family C25 - - - 0.0000000000000000000000000001732 134.0
MMD2_k127_3343529_1 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000164 107.0
MMD2_k127_3343529_2 PFAM DsrE K07235 - - 0.000000000000000265 83.0
MMD2_k127_3343529_3 TIGRFAM Outer membrane protein K13735,K20276 - - 0.00000000000006678 86.0
MMD2_k127_3343529_4 DsrE/DsrF-like family K07236 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.000000000192 67.0
MMD2_k127_3343796_0 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000002907 64.0
MMD2_k127_3343796_1 C-terminal domain of CHU protein family - - - 0.00001375 59.0
MMD2_k127_3344112_0 Periplasmic copper-binding protein (NosD) - - - 0.000001312 62.0
MMD2_k127_336527_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05559,K14086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 402.0
MMD2_k127_336527_1 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000007115 102.0
MMD2_k127_336527_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000004429 81.0
MMD2_k127_336527_3 PFAM respiratory-chain NADH dehydrogenase, subunit 1 K00337,K14087 - 1.6.5.3 0.000000000006455 67.0
MMD2_k127_336527_4 PFAM regulatory protein AsnC Lrp family - - - 0.0003288 50.0
MMD2_k127_3397766_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004795 244.0
MMD2_k127_3397766_1 PFAM HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000001836 223.0
MMD2_k127_3397766_2 - - - - 0.0000000000000000000000000000000000000217 150.0
MMD2_k127_3402272_0 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000004603 132.0
MMD2_k127_3402272_1 - - - - 0.00003752 56.0
MMD2_k127_3411568_0 Pfam:DUF650 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 464.0
MMD2_k127_3411568_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000002906 238.0
MMD2_k127_3411568_2 Transglutaminase-like - - - 0.0000000000007535 85.0
MMD2_k127_3411568_3 PFAM Prenyltransferase squalene oxidase - - - 0.00000003306 70.0
MMD2_k127_3413380_0 FAD binding domain K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 316.0
MMD2_k127_3422257_0 serine threonine protein kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000008609 228.0
MMD2_k127_3422257_1 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000004295 182.0
MMD2_k127_3422257_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000002812 111.0
MMD2_k127_3422257_3 Sulfur transfer protein involved in thiamine biosynthesis K03154,K21947 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 2.8.1.15 0.00004522 49.0
MMD2_k127_3427173_0 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009753 370.0
MMD2_k127_3427173_1 COG1404 Subtilisin-like serine proteases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000412 293.0
MMD2_k127_3427173_2 metallopeptidase activity K06974 - - 0.00000000000000000000000000001169 126.0
MMD2_k127_3430861_0 cell adhesion involved in biofilm formation K13735,K20276 - - 0.000000001139 72.0
MMD2_k127_3443108_0 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.0004068 53.0
MMD2_k127_3467352_0 Clostripain family - - - 0.0000000000000000000000001642 121.0
MMD2_k127_3467352_1 arsenical-resistance protein K03325 - - 0.0000000001238 74.0
MMD2_k127_3469688_0 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000001396 221.0
MMD2_k127_3469688_1 PFAM Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000001196 208.0
MMD2_k127_3469688_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000005951 175.0
MMD2_k127_3469688_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000000000000000000007788 154.0
MMD2_k127_3469688_4 lactoylglutathione lyase activity - - - 0.00000007387 59.0
MMD2_k127_3474573_0 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 3.169e-206 661.0
MMD2_k127_3474573_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000004911 202.0
MMD2_k127_3474573_2 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000005346 152.0
MMD2_k127_3474573_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000002456 148.0
MMD2_k127_3474573_4 Belongs to the eukaryotic ribosomal protein eS28 family K02979 - - 0.00000000000000000000000002675 115.0
MMD2_k127_3474573_5 Binds to the 23S rRNA K02896 - - 0.000000000000000000002201 94.0
MMD2_k127_3474573_6 metal-sulfur cluster biosynthetic enzyme K02612,K04488 - - 0.0000000000000000024 92.0
MMD2_k127_3474573_7 Bacterio-opsin activator HTH domain-containing protein K06930 - - 0.000000000005559 68.0
MMD2_k127_3479457_0 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000903 267.0
MMD2_k127_3479457_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000002457 253.0
MMD2_k127_3479457_2 Protein of unknown function (DUF1003) - - - 0.00000000000000000000000000000000000000004639 154.0
MMD2_k127_3493582_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004268 290.0
MMD2_k127_3493582_1 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000000000000000000000001646 155.0
MMD2_k127_3519842_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000004795 177.0
MMD2_k127_3519842_1 PFAM S-layer - - - 0.000006787 60.0
MMD2_k127_3520378_0 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000000000000000000000000002454 212.0
MMD2_k127_3520378_1 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000003181 151.0
MMD2_k127_3520378_2 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000002079 137.0
MMD2_k127_3520378_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000003114 98.0
MMD2_k127_3520378_4 COG1520 FOG WD40-like repeat K17713 - - 0.0000000002558 74.0
MMD2_k127_3520410_0 3-demethylubiquinone-9 3-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 347.0
MMD2_k127_3520410_1 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001974 251.0
MMD2_k127_3520410_2 haemagglutination activity domain - - - 0.0000000000000000000000000000000000000000001911 169.0
MMD2_k127_352760_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 408.0
MMD2_k127_352760_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.00000001249 59.0
MMD2_k127_3531327_0 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000000000000005234 238.0
MMD2_k127_3531327_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000009256 216.0
MMD2_k127_3531327_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000317 173.0
MMD2_k127_3531327_3 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000001386 99.0
MMD2_k127_3531327_4 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000002139 57.0
MMD2_k127_3534526_0 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000281 192.0
MMD2_k127_3534526_1 Protein of unknown function (DUF3795) - - - 0.00000000000005816 78.0
MMD2_k127_3541434_0 Bacterial Ig-like domain (group 3) K20276 - - 0.000000000000000287 95.0
MMD2_k127_3541434_1 Protein conserved in bacteria K20276 - - 0.000000000005334 79.0
MMD2_k127_3555662_0 UDP-N-acetyl-D-glucosamine 2-epimerase, UDP-hydrolysing K08068,K18429 - 3.2.1.183,3.2.1.184 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 289.0
MMD2_k127_3555662_1 TIGRFAM sugar O-acyltransferase, sialic acid O-acetyltransferase NeuD family K13006 - - 0.00000000000000000000000000000000000000001723 162.0
MMD2_k127_3555662_2 NAD-dependent epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.00000000000000000000006319 106.0
MMD2_k127_3563087_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 4.921e-196 636.0
MMD2_k127_3563087_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.00000000000000000615 87.0
MMD2_k127_3563087_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.0000000008476 68.0
MMD2_k127_3563087_3 Belongs to the UPF0201 family K09736 - - 0.0000000009617 66.0
MMD2_k127_3563087_4 Flavodoxin - - - 0.000001254 58.0
MMD2_k127_3573849_0 PFAM FecR protein - - - 0.00000000000000000005625 106.0
MMD2_k127_359022_0 S-layer homology domain - - - 0.00000000000000000000000002706 125.0
MMD2_k127_363644_0 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000004916 151.0
MMD2_k127_363644_1 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.000000000000000003863 100.0
MMD2_k127_3642378_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000251 299.0
MMD2_k127_3642378_1 Protein of unknown function TPD sequence-motif - - - 0.000000000000000000000000000000000000000001386 168.0
MMD2_k127_3652597_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 395.0
MMD2_k127_3652597_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000004845 245.0
MMD2_k127_3652597_2 Protein of unknown function (DUF835) - - - 0.00000000000885 72.0
MMD2_k127_3685028_0 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000003281 81.0
MMD2_k127_3697751_0 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004698 281.0
MMD2_k127_3697751_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000003124 257.0
MMD2_k127_3697751_2 - - - - 0.0000000006524 66.0
MMD2_k127_371032_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000003078 166.0
MMD2_k127_3730299_0 Belongs to the peptidase S8 family K17734 - - 0.0000000000000000000000000000000000000000000000000000000000000007204 239.0
MMD2_k127_373752_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 527.0
MMD2_k127_373752_1 ATPase, AAA superfamily K06921 - - 0.0000002632 52.0
MMD2_k127_3742028_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.226e-195 624.0
MMD2_k127_3742028_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 296.0
MMD2_k127_3742028_2 TIGRFAM ribosomal protein L30P K02907 - - 0.00000000000000000000000000000000000000000009863 173.0
MMD2_k127_3742028_3 Binds to the 23S rRNA K02876 - - 0.00000000000000000331 94.0
MMD2_k127_375513_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.151e-256 805.0
MMD2_k127_375513_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 3.731e-241 758.0
MMD2_k127_375513_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000201 249.0
MMD2_k127_375513_3 Beta propeller domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005307 256.0
MMD2_k127_375513_4 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000001062 244.0
MMD2_k127_375513_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000002594 230.0
MMD2_k127_375513_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000000000005106 111.0
MMD2_k127_375513_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.000000000000000003918 88.0
MMD2_k127_375513_8 F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K K02124 - - 0.0000000005207 62.0
MMD2_k127_3770739_0 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 310.0
MMD2_k127_3770739_1 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000007718 164.0
MMD2_k127_3772043_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 517.0
MMD2_k127_3772043_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 346.0
MMD2_k127_3772043_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000472 180.0
MMD2_k127_3772043_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000002467 84.0
MMD2_k127_3781594_0 isochorismatase - - - 0.000000000000000000000000000000000003511 145.0
MMD2_k127_3782222_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000002633 213.0
MMD2_k127_3782222_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000005803 123.0
MMD2_k127_3782222_2 pfam yhs - - - 0.0000000000181 67.0
MMD2_k127_3782222_3 Domain of unknown function - - - 0.0000000592 63.0
MMD2_k127_3782222_4 SNF2 family N-terminal domain - - - 0.00005038 53.0
MMD2_k127_3783318_0 phosphoglycerate kinase activity K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 355.0
MMD2_k127_3799003_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 1.281e-273 863.0
MMD2_k127_3810017_0 Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000003614 187.0
MMD2_k127_3810017_1 Fibronectin type III domain protein - - - 0.0000000000000000004047 100.0
MMD2_k127_3821944_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 4.914e-224 707.0
MMD2_k127_3821944_1 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 7.295e-209 663.0
MMD2_k127_3821944_2 exonuclease K07502 - - 0.00000000000000000000000000000000002252 141.0
MMD2_k127_3821944_3 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.0000000000000009782 90.0
MMD2_k127_3821944_4 3-demethylubiquinone-9 3-O-methyltransferase activity K16328 - 2.7.1.83 0.0000000000005512 71.0
MMD2_k127_383343_0 methanogenesis marker protein 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 319.0
MMD2_k127_383343_1 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003616 253.0
MMD2_k127_383343_2 Protein of unknown function (DUF429) - - - 0.000000000001718 77.0
MMD2_k127_3850785_0 HEPN domain - - - 0.0000000000000000000000001775 111.0
MMD2_k127_3850785_1 DNA polymerase beta - - - 0.000000000000000000003854 102.0
MMD2_k127_385798_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002253 245.0
MMD2_k127_385798_1 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000431 198.0
MMD2_k127_385798_2 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000508 89.0
MMD2_k127_385798_3 ATP cone domain - - - 0.00000006877 57.0
MMD2_k127_385798_4 ATP cone domain - - - 0.0001367 53.0
MMD2_k127_3863314_0 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000002116 243.0
MMD2_k127_3863314_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000103 71.0
MMD2_k127_3863314_2 HI0933-like protein K00313 - - 0.0001373 49.0
MMD2_k127_3865867_0 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 329.0
MMD2_k127_3865867_1 heterodisulfide reductase subunit C K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000003727 178.0
MMD2_k127_3865867_2 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000002697 119.0
MMD2_k127_3865867_3 PFAM CBS domain - - - 0.000000000000002931 79.0
MMD2_k127_3865867_4 Domain of unknown function (DUF749) - - - 0.00001613 51.0
MMD2_k127_3873979_0 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 379.0
MMD2_k127_3882925_0 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000003831 248.0
MMD2_k127_3882925_1 Alpha/beta hydrolase family - - - 0.00004621 57.0
MMD2_k127_3891504_0 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 389.0
MMD2_k127_3891504_1 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.0000000000000000000000000000000000000000000000000000000000000007389 241.0
MMD2_k127_3891504_2 amine dehydrogenase activity K20276 - - 0.0000000000000000000000000000000000000000000000000000000001135 235.0
MMD2_k127_3891504_3 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000004633 196.0
MMD2_k127_3891504_4 myosin light chain kinase activity K12567 - 2.7.11.1 0.0000000000000000000000000000000000001708 165.0
MMD2_k127_3891504_5 cyclic nucleotide gated channel alpha K04948,K04949,K04950,K04951 GO:0000003,GO:0000139,GO:0000166,GO:0000902,GO:0001558,GO:0001654,GO:0001666,GO:0001750,GO:0001754,GO:0003008,GO:0003031,GO:0003407,GO:0003674,GO:0005215,GO:0005216,GO:0005217,GO:0005221,GO:0005222,GO:0005223,GO:0005244,GO:0005249,GO:0005261,GO:0005267,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005798,GO:0005886,GO:0005887,GO:0005929,GO:0006355,GO:0006357,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0006873,GO:0006874,GO:0006875,GO:0006935,GO:0006950,GO:0007154,GO:0007165,GO:0007186,GO:0007187,GO:0007199,GO:0007275,GO:0007276,GO:0007283,GO:0007399,GO:0007423,GO:0007600,GO:0007601,GO:0007602,GO:0007603,GO:0007606,GO:0007608,GO:0007610,GO:0007635,GO:0008022,GO:0008150,GO:0008277,GO:0008324,GO:0008361,GO:0009266,GO:0009314,GO:0009416,GO:0009453,GO:0009454,GO:0009581,GO:0009582,GO:0009583,GO:0009584,GO:0009593,GO:0009605,GO:0009628,GO:0009653,GO:0009887,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010648,GO:0010752,GO:0010754,GO:0010769,GO:0010975,GO:0012505,GO:0014070,GO:0014074,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015276,GO:0015318,GO:0015672,GO:0016020,GO:0016021,GO:0016043,GO:0016056,GO:0017071,GO:0017076,GO:0019001,GO:0019219,GO:0019222,GO:0019722,GO:0019725,GO:0019932,GO:0019934,GO:0019935,GO:0019953,GO:0022008,GO:0022400,GO:0022414,GO:0022603,GO:0022604,GO:0022607,GO:0022803,GO:0022832,GO:0022834,GO:0022836,GO:0022838,GO:0022839,GO:0022843,GO:0022857,GO:0022890,GO:0023051,GO:0023052,GO:0023057,GO:0030001,GO:0030003,GO:0030030,GO:0030154,GO:0030182,GO:0030424,GO:0030425,GO:0030516,GO:0030551,GO:0030553,GO:0030660,GO:0031090,GO:0031175,GO:0031224,GO:0031226,GO:0031253,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031344,GO:0031410,GO:0031982,GO:0031984,GO:0032026,GO:0032101,GO:0032501,GO:0032502,GO:0032504,GO:0032535,GO:0032553,GO:0032555,GO:0032561,GO:0032989,GO:0032990,GO:0032991,GO:0033267,GO:0034220,GO:0034702,GO:0034703,GO:0035556,GO:0036094,GO:0036293,GO:0036296,GO:0036477,GO:0040008,GO:0040009,GO:0040010,GO:0040011,GO:0040040,GO:0042048,GO:0042221,GO:0042330,GO:0042391,GO:0042461,GO:0042462,GO:0042592,GO:0042622,GO:0042670,GO:0042995,GO:0043005,GO:0043010,GO:0043025,GO:0043052,GO:0043167,GO:0043168,GO:0043195,GO:0043204,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043679,GO:0043855,GO:0043933,GO:0044085,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044433,GO:0044441,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0045202,GO:0045595,GO:0045664,GO:0045893,GO:0045927,GO:0045935,GO:0045944,GO:0046530,GO:0046549,GO:0046683,GO:0046873,GO:0048232,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048592,GO:0048593,GO:0048609,GO:0048638,GO:0048666,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050767,GO:0050770,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050877,GO:0050896,GO:0050906,GO:0050907,GO:0050953,GO:0051128,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051239,GO:0051252,GO:0051254,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051290,GO:0051291,GO:0051480,GO:0051591,GO:0051606,GO:0051704,GO:0051716,GO:0051899,GO:0051960,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055085,GO:0055093,GO:0060041,GO:0060042,GO:0060170,GO:0060219,GO:0060255,GO:0060284,GO:0061387,GO:0065003,GO:0065007,GO:0065008,GO:0070482,GO:0071214,GO:0071478,GO:0071482,GO:0071804,GO:0071805,GO:0071840,GO:0071944,GO:0072503,GO:0072507,GO:0080090,GO:0090066,GO:0090596,GO:0097159,GO:0097367,GO:0097447,GO:0097458,GO:0097543,GO:0097708,GO:0097730,GO:0097731,GO:0097733,GO:0098588,GO:0098590,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098791,GO:0098793,GO:0098796,GO:0098805,GO:0099094,GO:0104004,GO:0120025,GO:0120035,GO:0120036,GO:0120038,GO:0120039,GO:0150034,GO:1901265,GO:1901363,GO:1901698,GO:1901700,GO:1902495,GO:1902531,GO:1902532,GO:1902680,GO:1903506,GO:1903508,GO:1990351,GO:2000026,GO:2000112,GO:2001141 - 0.00000001776 68.0
MMD2_k127_3891504_6 FMN binding - - - 0.00004862 52.0
MMD2_k127_3904341_0 Putative Ig domain - - - 0.000000000458 73.0
MMD2_k127_3926075_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 537.0
MMD2_k127_3926075_1 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000002025 136.0
MMD2_k127_3936103_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000003346 94.0
MMD2_k127_3936164_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007461 327.0
MMD2_k127_3936164_1 small GTP-binding protein K06945 - - 0.00000000007948 67.0
MMD2_k127_3936164_2 Pfam:KaiC - - - 0.00000004686 63.0
MMD2_k127_3946433_0 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000006883 144.0
MMD2_k127_3950589_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000101 279.0
MMD2_k127_3950589_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
MMD2_k127_3950589_2 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.000000000000000000000000000000000000000000000000000000000001185 222.0
MMD2_k127_3950589_3 Domain of unknown function K20276 - - 0.0000000000000000000000000007846 134.0
MMD2_k127_3950589_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000003914 79.0
MMD2_k127_3950589_5 TIGRFAM Outer membrane protein - - - 0.00000000000004132 88.0
MMD2_k127_3950589_6 MacB-like periplasmic core domain K02004 - - 0.0000000000004141 81.0
MMD2_k127_3950589_7 MacB-like periplasmic core domain K02004,K09808 - - 0.000000001857 70.0
MMD2_k127_3950589_8 Protein conserved in bacteria K20276 - - 0.000001972 60.0
MMD2_k127_3961382_0 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001012 279.0
MMD2_k127_3964981_0 4-hydroxy-tetrahydrodipicolinate reductase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 367.0
MMD2_k127_3964981_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 318.0
MMD2_k127_3964981_2 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000001108 151.0
MMD2_k127_3965156_0 Protein of unknown function, DUF255 K06888 - - 8.705e-238 754.0
MMD2_k127_3965156_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000001287 190.0
MMD2_k127_3965156_2 D,D-heptose 1,7-bisphosphate phosphatase K03273,K15669 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 2.7.7.71,3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000001434 164.0
MMD2_k127_3965156_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000002827 73.0
MMD2_k127_3965156_4 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000001158 59.0
MMD2_k127_3965156_5 protein conserved in archaea K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.0000006119 60.0
MMD2_k127_3976679_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000005418 277.0
MMD2_k127_3976679_1 PQQ enzyme repeat - - - 0.000000000000000000000000000000000001862 157.0
MMD2_k127_3976679_2 adenyl ribonucleotide binding - - - 0.0000000000000000000000000000000009727 138.0
MMD2_k127_3976679_3 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000000002217 128.0
MMD2_k127_3976679_4 Hemolysin-type calcium-binding repeat (2 copies) - - - 0.00000004317 66.0
MMD2_k127_3977108_0 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000002726 193.0
MMD2_k127_3977108_1 ribosomal protein S11 K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000006334 176.0
MMD2_k127_3977108_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000007131 166.0
MMD2_k127_3977108_3 protein contain chitin-binding domain type 3 - - - 0.000000000005845 80.0
MMD2_k127_3977108_4 OmpA family - - - 0.00000000001015 79.0
MMD2_k127_3977108_5 Belongs to the peptidase S8 family K13276,K17734 - - 0.0004651 54.0
MMD2_k127_3984557_0 Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K01083,K06131,K06915 - 3.1.3.8 0.00000000000000000000004033 115.0
MMD2_k127_3984557_1 Helix-turn-helix domain - - - 0.00000000002206 73.0
MMD2_k127_3984557_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K20276 - - 0.0000000001711 75.0
MMD2_k127_3987060_0 CARDB - - - 0.00008773 57.0
MMD2_k127_3992531_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 348.0
MMD2_k127_4002932_0 PFAM DNA methylase N-4 N-6 domain protein K00571 - 2.1.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 393.0
MMD2_k127_4002932_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 336.0
MMD2_k127_400957_0 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000000000968 202.0
MMD2_k127_4018387_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000001063 251.0
MMD2_k127_4021388_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.193e-294 930.0
MMD2_k127_4021388_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 6.631e-251 788.0
MMD2_k127_4021388_2 Bacterial transferase hexapeptide (six repeats) K02617,K08279 - - 0.00000000000000000000000000000000000000000000000000000000000000000000374 242.0
MMD2_k127_4021388_3 extracellular matrix structural constituent K02035 - - 0.0000001709 65.0
MMD2_k127_4021388_4 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.00001995 59.0
MMD2_k127_4022779_0 DHH family - - - 0.0000000000000000000000001878 118.0
MMD2_k127_4022779_1 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.00000000001292 71.0
MMD2_k127_4037026_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 464.0
MMD2_k127_4037026_1 Isocitrate isopropylmalate dehydrogenase K10978 - 1.1.1.87 0.000000000000000000000000000000000000000000000000000000009665 207.0
MMD2_k127_4037026_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000001891 196.0
MMD2_k127_4037026_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000001131 167.0
MMD2_k127_4066116_0 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.00004151 56.0
MMD2_k127_4074091_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000004055 194.0
MMD2_k127_4074091_1 GvpD gas vesicle protein - - - 0.000000000000000000000000000000000000000001547 164.0
MMD2_k127_4074091_2 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000002328 72.0
MMD2_k127_4074091_3 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0001742 47.0
MMD2_k127_4081795_0 S-layer homology domain - - - 0.000000000000000000000001161 121.0
MMD2_k127_4081795_1 Right handed beta helix region - - - 0.00001821 58.0
MMD2_k127_4087467_0 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000001935 208.0
MMD2_k127_4087467_1 von Willebrand factor (vWF) type A domain - - - 0.0003194 52.0
MMD2_k127_4094832_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000003182 278.0
MMD2_k127_4094832_1 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
MMD2_k127_4094832_2 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000000004819 115.0
MMD2_k127_4094832_3 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.000000000000000006324 86.0
MMD2_k127_4094832_4 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000002052 79.0
MMD2_k127_4094832_5 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000000005943 69.0
MMD2_k127_4096603_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 2.949e-195 623.0
MMD2_k127_4096603_1 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.0000000000000000000001689 97.0
MMD2_k127_4096603_2 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000003757 89.0
MMD2_k127_4098381_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 341.0
MMD2_k127_4098381_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000008359 196.0
MMD2_k127_4098381_2 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000006397 98.0
MMD2_k127_4107028_0 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.0 1017.0
MMD2_k127_4107028_1 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006327 490.0
MMD2_k127_4107028_2 Cys Met metabolism K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.000000000000000000000000000002153 123.0
MMD2_k127_4131345_0 Beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 340.0
MMD2_k127_4131345_1 S-layer homology domain - - - 0.00000000000000000000000000006551 134.0
MMD2_k127_4131345_2 C-terminal domain of CHU protein family - - - 0.000000000000000005467 95.0
MMD2_k127_4138560_0 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000002157 139.0
MMD2_k127_4138560_1 Putative TM nitroreductase - - - 0.000000000000000000000000004885 113.0
MMD2_k127_4138560_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.00000000000000000000000005862 123.0
MMD2_k127_4138560_3 Aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000000000000009243 79.0
MMD2_k127_414540_0 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 311.0
MMD2_k127_414540_1 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007924 273.0
MMD2_k127_414540_2 COG3291 FOG PKD repeat - - - 0.00000000000000000000000000000000000000000000000001966 201.0
MMD2_k127_4149133_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 312.0
MMD2_k127_4149133_1 COG2931 RTX toxins and related Ca2 -binding - - - 0.0000000000004775 83.0
MMD2_k127_4159851_0 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.000000000001438 68.0
MMD2_k127_4159851_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000000000009427 79.0
MMD2_k127_4159851_2 S-layer homology domain - - - 0.0000002227 61.0
MMD2_k127_419156_0 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008104 291.0
MMD2_k127_419156_1 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000001108 161.0
MMD2_k127_419156_2 PFAM Glycosyl transferase family 2 - - - 0.0000000005284 68.0
MMD2_k127_419156_3 Right handed beta helix region - - - 0.0000146 58.0
MMD2_k127_4214641_0 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007207 324.0
MMD2_k127_4214641_1 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000002673 272.0
MMD2_k127_4214641_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000000000000000004965 200.0
MMD2_k127_4214641_3 PAS domain K02488 - 2.7.7.65 0.0000000000000000000000000000000000000105 168.0
MMD2_k127_4214641_4 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000004765 140.0
MMD2_k127_4214641_5 - - - - 0.000005201 55.0
MMD2_k127_423642_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 310.0
MMD2_k127_423642_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006414 312.0
MMD2_k127_423642_2 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004137 246.0
MMD2_k127_423642_3 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000542 215.0
MMD2_k127_423642_4 NADH-quinone oxidoreductase K03940 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000005338 135.0
MMD2_k127_423642_5 Rhomboid family - - - 0.0000000000000000000007918 107.0
MMD2_k127_423642_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000001299 85.0
MMD2_k127_4241243_0 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000001309 75.0
MMD2_k127_4263002_0 COG3291 FOG PKD repeat - - - 0.00000000000000000000000000000000000000000000000000003359 214.0
MMD2_k127_4263002_1 Double zinc ribbon - - - 0.0000000008801 60.0
MMD2_k127_4268149_0 E1-E2 ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000832 454.0
MMD2_k127_4270955_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 6.086e-196 623.0
MMD2_k127_4270955_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000001362 184.0
MMD2_k127_4286488_0 - - - - 0.00000000000000000000000001038 115.0
MMD2_k127_4286488_1 subfamily IA, variant 1 K20862 - 3.1.3.102,3.1.3.104 0.00000000000823 67.0
MMD2_k127_4294093_0 PFAM carboxyl transferase - - - 2.549e-194 613.0
MMD2_k127_4303214_0 Ethylbenzene dehydrogenase - - - 0.00000000000000000002424 108.0
MMD2_k127_4303214_1 CARDB - - - 0.00000000003925 78.0
MMD2_k127_4329778_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007104 302.0
MMD2_k127_4329778_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000004475 201.0
MMD2_k127_4329778_2 Bacterial Ig-like domain (group 3) K20276 - - 0.000000000000000000003919 110.0
MMD2_k127_4329778_3 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000004776 71.0
MMD2_k127_4363757_0 Inter-alpha-trypsin inhibitor heavy chain 3 - GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0006810,GO:0006887,GO:0008150,GO:0009892,GO:0009987,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034774,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.000000000000000000000000000000007543 143.0
MMD2_k127_4363757_1 Inter-alpha-trypsin inhibitor heavy chain - - - 0.0000000000000006705 88.0
MMD2_k127_4370926_0 membrane K08971 - - 0.0000000000000000000005891 109.0
MMD2_k127_4370926_1 Trehalose utilisation K01179 - 3.2.1.4 0.00000000000000000002762 107.0
MMD2_k127_4373667_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001185 308.0
MMD2_k127_4373667_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000003431 133.0
MMD2_k127_4373667_2 PFAM Di-glucose binding within endoplasmic reticulum - - - 0.00000000003898 77.0
MMD2_k127_4381687_0 WD-40 repeat - - - 0.0000002789 65.0
MMD2_k127_4381687_1 PFAM Hemolysin-type calcium-binding region - - - 0.0008134 54.0
MMD2_k127_4385183_0 Protein of unknown function (DUF3788) - - - 0.000000000000000000000005619 106.0
MMD2_k127_4385183_1 Molybdopterin guanine dinucleotide synthesis protein B K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.0000000000002596 78.0
MMD2_k127_4385183_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000005269 70.0
MMD2_k127_4385183_3 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000004873 57.0
MMD2_k127_4395611_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000001024 118.0
MMD2_k127_4395611_1 PFAM GvpD gas vesicle - - - 0.0000000000000003626 90.0
MMD2_k127_4395611_2 heat shock protein binding - - - 0.0005016 42.0
MMD2_k127_4402488_0 PFAM FecR protein - - - 0.000000000001499 81.0
MMD2_k127_4405992_0 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000004575 210.0
MMD2_k127_4405992_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000003663 167.0
MMD2_k127_4405992_2 PFAM DNA polymerase, beta domain protein region K07075 - - 0.000000000000000000000000006363 112.0
MMD2_k127_4405992_3 Protein of unknown function DUF86 - - - 0.00000000000000000000000008114 111.0
MMD2_k127_4405992_4 HEPN domain - - - 0.000000000000000000003441 100.0
MMD2_k127_4405992_5 Domain of unknown function (DU1801) - - - 0.0000000000000000009543 91.0
MMD2_k127_4405992_6 nucleotidyltransferase activity - - - 0.000000000007055 71.0
MMD2_k127_4405992_7 Domain of unknown function (DU1801) - - - 0.00000008366 57.0
MMD2_k127_4417849_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000005638 256.0
MMD2_k127_4434034_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
MMD2_k127_4434034_1 HEPN domain K09132 - - 0.0000000000003522 74.0
MMD2_k127_4434034_2 Nucleotidyltransferase domain - - - 0.00000000001573 72.0
MMD2_k127_4445511_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 442.0
MMD2_k127_4445511_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.0000000000000000000000000000000000000000000001927 190.0
MMD2_k127_4445511_2 PAS fold - - - 0.00000000000000000002224 107.0
MMD2_k127_4445511_3 RNase L inhibitor K06174 - - 0.00000002403 55.0
MMD2_k127_4445511_4 but it may be involved in stabilization of the trimeric complex - - - 0.00000002746 56.0
MMD2_k127_4445511_5 Helix-turn-helix domain - - - 0.0000001379 58.0
MMD2_k127_4448543_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 574.0
MMD2_k127_4448543_1 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 379.0
MMD2_k127_4448543_2 PFAM Glycosyl transferase, group 1 K16150 - 2.4.1.11 0.00000000000000000000000000000000000000003432 175.0
MMD2_k127_4448543_3 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000001315 163.0
MMD2_k127_4448543_4 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000002817 155.0
MMD2_k127_4448543_5 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000004571 86.0
MMD2_k127_4466255_0 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000006213 235.0
MMD2_k127_4466255_1 DnaB-like helicase C terminal domain - - - 0.00000000000000000000000000000000000003797 152.0
MMD2_k127_4466255_2 PFAM MazG nucleotide pyrophosphohydrolase domain - - - 0.00000000000000005149 90.0
MMD2_k127_4470084_0 amine dehydrogenase activity - - - 0.00000000000000000000000002125 126.0
MMD2_k127_4517625_0 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009854 354.0
MMD2_k127_4517625_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003605 282.0
MMD2_k127_4517625_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.000000000000008051 76.0
MMD2_k127_4517625_3 - - - - 0.0000003009 57.0
MMD2_k127_4522285_0 Multicopper K06324 - 1.16.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008908 441.0
MMD2_k127_4522285_1 Fibronectin type III domain - - - 0.000000000000001712 91.0
MMD2_k127_4523173_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000006645 147.0
MMD2_k127_4526106_0 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000000000000000000000001093 221.0
MMD2_k127_4526106_2 PFAM methyltransferase small K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.0000000000000000000000000000007735 130.0
MMD2_k127_4526106_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000001413 109.0
MMD2_k127_4526106_4 FlgD Ig-like domain K15924 - 3.2.1.136 0.00000003589 68.0
MMD2_k127_4526106_5 4Fe-4S binding domain - - - 0.000004033 59.0
MMD2_k127_4544871_0 threonine synthase activity K01733,K15527 - 2.5.1.76,4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005229 492.0
MMD2_k127_4544871_1 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 487.0
MMD2_k127_4544871_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000002656 137.0
MMD2_k127_4544871_3 COG1404 Subtilisin-like serine proteases K13276 GO:0005575,GO:0005576 - 0.000008035 57.0
MMD2_k127_4545435_0 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000002596 195.0
MMD2_k127_4545435_1 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 0.00000000000000000000000000000000000000000000005196 172.0
MMD2_k127_4545435_2 WD-40 repeat - - - 0.0000000000000000000000000000001114 145.0
MMD2_k127_4545435_3 SMART Integrin alpha beta-propellor repeat protein - - - 0.0000000000000000001172 104.0
MMD2_k127_4546330_0 SMART Parallel beta-helix repeat - - - 0.0000109 58.0
MMD2_k127_4549354_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 8.538e-294 925.0
MMD2_k127_4552894_0 PFAM PKD domain containing protein - - - 0.00006684 56.0
MMD2_k127_4552917_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 541.0
MMD2_k127_4552917_1 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000001635 213.0
MMD2_k127_4552917_2 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000006811 58.0
MMD2_k127_4565339_0 Cellulase N-terminal ig-like domain K01179 - 3.2.1.4 0.00007612 57.0
MMD2_k127_457421_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 7.122e-265 850.0
MMD2_k127_457421_1 Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000000000000000004545 117.0
MMD2_k127_457421_2 Conserved repeat domain - - - 0.0002742 55.0
MMD2_k127_4587153_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 393.0
MMD2_k127_4587153_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002116 383.0
MMD2_k127_4587153_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
MMD2_k127_4587153_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006525 319.0
MMD2_k127_4587153_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000171 287.0
MMD2_k127_4587153_5 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000003106 140.0
MMD2_k127_4587153_6 SPFH Band 7 PHB domain protein K07192 - - 0.000000000000000001991 93.0
MMD2_k127_4587882_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000000001452 162.0
MMD2_k127_4587882_1 protein conserved in archaea - - - 0.00000000000003398 79.0
MMD2_k127_4594901_0 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 316.0
MMD2_k127_4594901_1 transmembrane transport K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002942 298.0
MMD2_k127_4597274_0 Fungalysin metallopeptidase (M36) - - - 0.0000000000000000002659 103.0
MMD2_k127_4597274_1 Belongs to the ompA family K20276 - - 0.000005305 53.0
MMD2_k127_4602508_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000576 270.0
MMD2_k127_4602508_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000002395 212.0
MMD2_k127_4602508_2 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000001291 107.0
MMD2_k127_4602720_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 336.0
MMD2_k127_4602720_2 - - - - 0.00000000000000000002653 91.0
MMD2_k127_4602720_3 PFAM FecR protein K09800,K13735 - - 0.0000000000000008425 93.0
MMD2_k127_4602720_6 Tetratricopeptide repeat - - - 0.000000000288 72.0
MMD2_k127_4602720_7 4 iron, 4 sulfur cluster binding - - - 0.0000005662 62.0
MMD2_k127_4602720_8 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein K02557,K03286 - - 0.00002702 59.0
MMD2_k127_4602720_9 - - - - 0.00004633 46.0
MMD2_k127_4607329_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.216e-290 902.0
MMD2_k127_4607329_1 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 9.966e-207 657.0
MMD2_k127_4607329_2 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000213 237.0
MMD2_k127_4615239_0 Intracellular protease, PfpI K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000003354 178.0
MMD2_k127_4615239_1 glyoxalase bleomycin resistance protein dioxygenase K07032 - - 0.000000000000000000000000000000000000000000009894 170.0
MMD2_k127_4615239_2 conserved protein, contains double-stranded beta-helix domain K00450,K06720 - 1.13.11.4,4.2.1.108 0.000000000000000000000008842 104.0
MMD2_k127_4616807_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 339.0
MMD2_k127_4616807_1 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000001348 139.0
MMD2_k127_4632780_0 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000627 261.0
MMD2_k127_4632780_1 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000007142 194.0
MMD2_k127_4632780_2 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000003091 129.0
MMD2_k127_4632780_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0001514 48.0
MMD2_k127_4632780_4 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000297 51.0
MMD2_k127_4638885_0 PFAM FecR protein K09800,K13735 - - 0.000000000000000001013 102.0
MMD2_k127_4638885_1 COG2931, RTX toxins and related Ca2 -binding proteins K01406,K07004,K20276 - 3.4.24.40 0.0007167 52.0
MMD2_k127_4646965_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 450.0
MMD2_k127_4646965_1 PFAM PKD domain containing protein - - - 0.000000000000000000633 103.0
MMD2_k127_4647193_0 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 396.0
MMD2_k127_4647193_1 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000005617 170.0
MMD2_k127_4647193_2 Domain of unknown function (DUF4350) - - - 0.000000644 61.0
MMD2_k127_4647193_3 Belongs to the peptidase S8 family K20276 - - 0.0004746 54.0
MMD2_k127_4647193_4 RecR protein - - - 0.0007406 53.0
MMD2_k127_4675551_0 Catalyzes the deamination of 5'-deoxyadenosine into 5'- deoxyinosine. May be involved in the recycling of 5'- deoxyadenosine, whereupon the 5'-deoxyribose moiety of 5'- deoxyinosine is further metabolized to deoxyhexoses used for the biosynthesis of aromatic amino acids in methanogens. Is also able to deaminate 5-methylthioadenosine, S-adenosyl-L-homocysteine and adenosine to a small extent K12960 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 401.0
MMD2_k127_4675551_1 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.000000000000000000000000000000000000000000000008936 183.0
MMD2_k127_4675551_2 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000121 147.0
MMD2_k127_4675893_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 420.0
MMD2_k127_4675893_1 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000000000001202 168.0
MMD2_k127_4675893_2 Putative RNA methylase family UPF0020 K07446 - 2.1.1.213 0.00000000000000000000000000000000001012 148.0
MMD2_k127_4675893_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000001776 92.0
MMD2_k127_4696792_0 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000003038 189.0
MMD2_k127_4696792_1 Psort location CytoplasmicMembrane, score K16927 - - 0.000000000000000000000000000000000000000000006785 178.0
MMD2_k127_4696792_2 part of an ABC transporter complex. Responsible for energy coupling to the transport system K16785,K16786,K16787 - - 0.000000000000000000007423 96.0
MMD2_k127_4708722_0 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000135 216.0
MMD2_k127_4708722_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000000000000000000000000000006651 162.0
MMD2_k127_4708722_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000007638 136.0
MMD2_k127_4708722_3 - - - - 0.00000000000009066 75.0
MMD2_k127_4708722_4 TPR repeat - - - 0.0008836 48.0
MMD2_k127_4709516_0 RHS Repeat - - - 0.0000000004651 73.0
MMD2_k127_4714350_0 Glycosyltransferase, group 2 family protein K07011 - - 0.00000000000000000000000008443 120.0
MMD2_k127_4714350_1 UDP-N-acetylglucosamine 2-epimerase - - - 0.0000000002107 73.0
MMD2_k127_4717539_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001069 256.0
MMD2_k127_4717539_1 S53, subtilisin kexin sedolisin - - - 0.0000000000002232 86.0
MMD2_k127_4717539_2 WD40 repeat, subgroup - - - 0.0001482 57.0
MMD2_k127_4718230_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003467 250.0
MMD2_k127_4718230_2 - - - - 0.000000000001901 76.0
MMD2_k127_4718230_3 protein containing a NRPS condensation (Elongation) domain - - - 0.00000001275 66.0
MMD2_k127_4718230_4 ABC-2 family transporter protein K01992 - - 0.0000003306 54.0
MMD2_k127_4723468_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002601 447.0
MMD2_k127_4723468_1 PFAM aminotransferase class I and II K10907 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 332.0
MMD2_k127_4723468_2 Belongs to the eIF-2B alpha beta delta subunits family K03680 - - 0.0000000000000000000000000001029 128.0
MMD2_k127_4735069_0 Carbohydrate esterase family 3 protein - - - 0.000000000000000000000000000000000001856 162.0
MMD2_k127_4735996_0 prosthetic group binding K01644,K01646,K18292 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0008815,GO:0009346,GO:0009987,GO:0015980,GO:0016829,GO:0016830,GO:0016833,GO:0032991,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 4.1.3.25,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000001895 253.0
MMD2_k127_4735996_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000002862 146.0
MMD2_k127_4735996_2 PFAM Citrate lyase, alpha subunit K01643 - 2.8.3.10 0.0000000000000000000829 96.0
MMD2_k127_4746830_0 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000006455 136.0
MMD2_k127_4746830_1 lipase activity K15125 - - 0.0000000000009182 81.0
MMD2_k127_4746892_0 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 349.0
MMD2_k127_4746892_1 PFAM Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000006732 136.0
MMD2_k127_4755095_0 TIGRFAM TraB family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003462 263.0
MMD2_k127_4755095_1 COG1226 Kef-type K transport systems - - - 0.000000000000000000000000000000000000000000000000000001784 211.0
MMD2_k127_4755095_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000004914 62.0
MMD2_k127_4765614_0 helicase superfamily c-terminal domain K03724 - - 7.6e-204 661.0
MMD2_k127_4767956_0 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000003293 228.0
MMD2_k127_4767956_1 YoaP-like - - - 0.0000003216 61.0
MMD2_k127_4767956_2 YoaP-like - - - 0.0001354 53.0
MMD2_k127_4767956_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0009931 51.0
MMD2_k127_4768661_0 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000007603 172.0
MMD2_k127_4768661_1 Formiminotransferase-cyclodeaminase K01746 - 4.3.1.4 0.0000000000000000000000000000000000004385 147.0
MMD2_k127_4768661_2 COG1361 S-layer domain - - - 0.0000000000001835 85.0
MMD2_k127_4778283_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000007814 104.0
MMD2_k127_4780799_0 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000001385 240.0
MMD2_k127_4780799_1 peptidase U62, modulator of DNA gyrase - - - 0.00000001511 66.0
MMD2_k127_4793114_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 403.0
MMD2_k127_4793305_0 Papain family cysteine protease - - - 0.000000000000001342 91.0
MMD2_k127_4793305_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000002889 53.0
MMD2_k127_4793305_2 Myomesin 1a (skelemin) - - - 0.000001812 61.0
MMD2_k127_4802418_0 FG-GAP repeat - - - 0.0000000001068 76.0
MMD2_k127_4802418_1 TIGRFAM conserved repeat domain protein - - - 0.00002572 58.0
MMD2_k127_4802706_0 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 458.0
MMD2_k127_4802706_1 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000002986 228.0
MMD2_k127_4802706_2 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000000000000002308 119.0
MMD2_k127_4806386_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000781 273.0
MMD2_k127_4822179_0 PFAM NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000007821 213.0
MMD2_k127_483119_0 PEP-utilising enzyme, mobile domain K01006,K01007 - 2.7.9.1,2.7.9.2 1.165e-262 843.0
MMD2_k127_483119_1 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000006925 203.0
MMD2_k127_483119_2 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000006169 204.0
MMD2_k127_483119_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000006289 120.0
MMD2_k127_483119_4 to SP P29212 GB L02649 GB X70994 PID 581070 GB U00096 percent identity K00666,K01897 - 6.2.1.3 0.000000000000000000000000162 112.0
MMD2_k127_483119_5 CcmB protein K02194 - - 0.000000000000002067 88.0
MMD2_k127_4833003_0 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000003841 252.0
MMD2_k127_4834106_0 PFAM Flavodoxin K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 589.0
MMD2_k127_4834106_1 Ferritin-like domain - GO:0003674,GO:0003824,GO:0004601,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0016692,GO:0022900,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002702 264.0
MMD2_k127_4834106_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000005463 223.0
MMD2_k127_4834106_3 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000002934 162.0
MMD2_k127_4834106_4 Rubrerythrin - - - 0.000000000000000000000000000002703 125.0
MMD2_k127_4834106_5 Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000004102 106.0
MMD2_k127_4834106_6 iron ion binding - - - 0.00000000000009921 79.0
MMD2_k127_4834106_7 Major facilitator superfamily - - - 0.0000000000008602 81.0
MMD2_k127_4834106_8 CarboxypepD_reg-like domain K13276 - - 0.0002042 51.0
MMD2_k127_4838964_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000007213 250.0
MMD2_k127_4838964_1 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000002811 231.0
MMD2_k127_4838964_2 amino acid activation for nonribosomal peptide biosynthetic process K17713,K20952 - - 0.0000005617 58.0
MMD2_k127_4840209_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 321.0
MMD2_k127_4840209_1 Protein involved in outer membrane biogenesis - - - 0.0000000008031 70.0
MMD2_k127_4840209_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.00000000239 62.0
MMD2_k127_4842498_0 Domain of unknown function K20276 - - 0.000000000000000000008133 110.0
MMD2_k127_4848676_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 570.0
MMD2_k127_4848676_1 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 531.0
MMD2_k127_4848676_2 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 400.0
MMD2_k127_4848676_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 398.0
MMD2_k127_4848676_4 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000001725 212.0
MMD2_k127_4848676_5 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.000000000000000000000000000000000000000000008251 173.0
MMD2_k127_4848676_6 4Fe-4S binding domain - - - 0.00000000001155 76.0
MMD2_k127_4848967_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 476.0
MMD2_k127_4848967_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000186 153.0
MMD2_k127_4848967_2 Lrp/AsnC ligand binding domain - - - 0.00000000000000001063 86.0
MMD2_k127_4848967_3 response regulator, receiver - - - 0.00000000000000001329 87.0
MMD2_k127_4859739_0 Heat shock 70 kDa protein K04043 - - 8.153e-244 766.0
MMD2_k127_4859739_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000001514 75.0
MMD2_k127_4870904_0 phenylacetate-CoA ligase activity K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000003586 198.0
MMD2_k127_4870904_1 shikimate kinase activity K00891 - 2.7.1.71 0.00000000000000000000000000000000000001399 160.0
MMD2_k127_4870904_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K04040,K20616 - 2.5.1.133,2.5.1.62 0.0007335 51.0
MMD2_k127_4871822_0 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009382 261.0
MMD2_k127_4871822_1 Chlorophyll synthase, ChlG K04040 - 2.5.1.133,2.5.1.62 0.00000000000000000003474 103.0
MMD2_k127_4871822_2 Integral membrane protein DUF92 - - - 0.000000000000000000195 98.0
MMD2_k127_4889385_0 NADH-ubiquinone oxidoreductase chain 49kDa K00333,K14090 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003556 357.0
MMD2_k127_4889385_1 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009751 271.0
MMD2_k127_4889385_2 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000004198 187.0
MMD2_k127_4889385_3 4Fe-4S binding domain - - - 0.00000000000000000000003391 103.0
MMD2_k127_4889385_4 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K00332 - 1.6.5.3 0.00004781 50.0
MMD2_k127_4904460_0 membrane - - - 0.00000000000008045 84.0
MMD2_k127_4911127_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008612,GO:0009058,GO:0009987,GO:0010467,GO:0016740,GO:0016765,GO:0018193,GO:0018205,GO:0019538,GO:0034038,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 332.0
MMD2_k127_4911127_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000006159 240.0
MMD2_k127_4911127_2 TatD related DNase K07049 - - 0.000000000000000000000000000000000000000000000000000000000000000114 231.0
MMD2_k127_4911127_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000007824 88.0
MMD2_k127_4911127_4 protein conserved in archaea - - - 0.00000009568 64.0
MMD2_k127_491760_0 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001221 281.0
MMD2_k127_491760_1 S-layer homology domain - - - 0.00000000000000000000000006354 126.0
MMD2_k127_491760_2 PA14 - - - 0.0000000000000007368 93.0
MMD2_k127_4920893_0 Ethylbenzene dehydrogenase - - - 0.00000000000000000000007547 114.0
MMD2_k127_4920893_1 CARDB - - - 0.00000001574 64.0
MMD2_k127_4920893_2 COG0500 SAM-dependent methyltransferases - - - 0.000182 49.0
MMD2_k127_4930948_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000219 83.0
MMD2_k127_493843_0 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 306.0
MMD2_k127_493843_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000001322 229.0
MMD2_k127_493843_2 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.000002641 51.0
MMD2_k127_4939471_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000003668 230.0
MMD2_k127_4939471_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000242 98.0
MMD2_k127_4939471_2 Tetratricopeptide repeat - - - 0.000000000006382 71.0
MMD2_k127_4939471_3 Tetratricopeptide repeat - - - 0.00000000005372 66.0
MMD2_k127_4943139_0 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000009624 121.0
MMD2_k127_4943139_1 FtsX-like permease family - - - 0.0000003925 58.0
MMD2_k127_4943139_2 Alpha-1,2-mannosidase - - - 0.0003343 54.0
MMD2_k127_4972669_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 536.0
MMD2_k127_4972669_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000001477 224.0
MMD2_k127_4972669_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000001263 98.0
MMD2_k127_4973706_0 self proteolysis K21449 - - 0.0000000003003 71.0
MMD2_k127_4973706_1 Bacterial Ig-like domain - - - 0.0006455 53.0
MMD2_k127_4981623_0 LemA family K03744 - - 0.0000000000000000000000000000000003712 139.0
MMD2_k127_4981623_1 TPM domain K06872 - - 0.00000000000000000000000000008668 127.0
MMD2_k127_4981623_2 Mycolic acid cyclopropane synthetase - - - 0.000000000000002931 79.0
MMD2_k127_4986192_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 498.0
MMD2_k127_4986192_1 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007085 293.0
MMD2_k127_4987643_0 TIGRFAM MIP family channel K02440,K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002732 279.0
MMD2_k127_4987643_1 NAD(P)H-binding - - - 0.0000000000000000000000000000004017 135.0
MMD2_k127_4987643_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000001047 117.0
MMD2_k127_4991370_0 RibD C-terminal domain K14654 - 1.1.1.302 0.00000000000000000000000000000000000000000000000000000001083 207.0
MMD2_k127_4991370_1 Transcriptional regulator, ArsR family - - - 0.0000000000000000000000001146 109.0
MMD2_k127_4991370_2 O-methyltransferase activity - - - 0.0000000000000000015 95.0
MMD2_k127_4991370_3 domain protein K16191,K20276 - - 0.0000000008023 65.0
MMD2_k127_4999276_0 glycoside hydrolase, family - - - 6.946e-194 675.0
MMD2_k127_5005888_0 electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0016628,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071949,GO:0097159,GO:1901265,GO:1901363 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 445.0
MMD2_k127_5005888_1 electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 328.0
MMD2_k127_5005888_2 Domain of unknown function (DUF296) K06934 - - 0.000000000000000000002096 109.0
MMD2_k127_5011326_0 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000000000002051 231.0
MMD2_k127_5019929_0 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000007662 94.0
MMD2_k127_5028955_0 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000000002509 218.0
MMD2_k127_5028955_1 OmpA family - - - 0.00000000000002809 87.0
MMD2_k127_5042613_0 Subtilase family K01342 - 3.4.21.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 302.0
MMD2_k127_5081119_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 442.0
MMD2_k127_5081119_1 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005482 424.0
MMD2_k127_5081119_2 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002286 253.0
MMD2_k127_5081119_3 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.000000006555 66.0
MMD2_k127_5094379_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 407.0
MMD2_k127_5094379_1 PFAM ATP-NAD AcoX kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002964 251.0
MMD2_k127_5109364_0 Bacterial Ig-like domain (group 3) - - - 0.0000000001571 72.0
MMD2_k127_5119467_0 Belongs to the N(4) N(6)-methyltransferase family - - - 0.000000000000000000000001309 103.0
MMD2_k127_5120017_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 507.0
MMD2_k127_5120017_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 343.0
MMD2_k127_5120017_2 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005132 344.0
MMD2_k127_5120017_3 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000000003742 86.0
MMD2_k127_5143025_0 TIGRFAM conserved repeat domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001029 294.0
MMD2_k127_5143025_1 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000008401 198.0
MMD2_k127_5143025_2 PFAM SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000891 186.0
MMD2_k127_5143025_3 Immunoglobulin like K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.00000000000002585 88.0
MMD2_k127_5164436_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 418.0
MMD2_k127_5164436_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 320.0
MMD2_k127_5164436_2 PFAM GPR1 FUN34 yaaH family K07034 - - 0.0000000000000000000000000000000000000000000000000000000317 205.0
MMD2_k127_5180264_0 CarboxypepD_reg-like domain K13276 - - 0.00000000000027 85.0
MMD2_k127_5180264_1 Belongs to the peptidase S8 family K13276,K17734 - - 0.000000000008509 75.0
MMD2_k127_5181530_0 domain, Protein - - - 0.000000000000000000000000000003163 138.0
MMD2_k127_5185391_0 OPT oligopeptide transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 438.0
MMD2_k127_5185391_1 Integral membrane sensor signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000009174 215.0
MMD2_k127_5185391_2 cheY-homologous receiver domain K07668 - - 0.00000000000000000000000000437 117.0
MMD2_k127_5185391_3 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.000000001847 69.0
MMD2_k127_5192706_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000008428 79.0
MMD2_k127_5194297_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1138.0
MMD2_k127_5194297_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000001564 84.0
MMD2_k127_5194508_0 DNA polymerase X family K02347,K04477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 518.0
MMD2_k127_5194508_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 409.0
MMD2_k127_5194508_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972,K02342,K04096,K12472 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016874,GO:0016886,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0040007,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 2.7.7.7,6.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000003406 267.0
MMD2_k127_5195555_0 Belongs to the glycosyl hydrolase family 6 K19668 - 3.2.1.91 0.000000000000000000000000000000000000000000002195 190.0
MMD2_k127_5195555_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000005475 74.0
MMD2_k127_519564_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.00000000000000000000000000000000000005573 146.0
MMD2_k127_519564_1 Transcriptional regulator, ArsR family - - - 0.0000000000002711 85.0
MMD2_k127_519564_2 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0009916 53.0
MMD2_k127_5211037_0 PFAM Rieske 2Fe-2S domain K15878 - - 0.00000000000004389 80.0
MMD2_k127_5211037_1 - - - - 0.00000003189 61.0
MMD2_k127_5211037_2 Bacterial Ig-like domain - - - 0.000003312 59.0
MMD2_k127_5216425_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008018 259.0
MMD2_k127_5216425_1 Putative zinc- or iron-chelating domain K06940 - - 0.0000008885 59.0
MMD2_k127_5224349_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000000002489 91.0
MMD2_k127_5225825_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 431.0
MMD2_k127_5225825_1 PAS domain - - - 0.000000000000001791 91.0
MMD2_k127_5225825_2 nuclear chromosome segregation - - - 0.0000000000001994 85.0
MMD2_k127_5281685_0 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 342.0
MMD2_k127_5281685_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000005764 197.0
MMD2_k127_5281685_2 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000002601 181.0
MMD2_k127_5296673_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 580.0
MMD2_k127_5296673_1 Aminopeptidase I zinc metalloprotease (M18) K01267 - 3.4.11.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 502.0
MMD2_k127_5296673_2 PQQ-like domain - - - 0.0000000000000000000000000000004328 143.0
MMD2_k127_5296673_3 PQQ-like domain - - - 0.0000000009244 73.0
MMD2_k127_5296673_4 COG3291 FOG PKD repeat - - - 0.00000007586 66.0
MMD2_k127_5297096_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008783 306.0
MMD2_k127_5297096_1 PFAM ATPase, BadF BadG BcrA BcrD type K09680 - 2.7.1.33 0.0000000000000000000000000000000000003477 159.0
MMD2_k127_5306002_0 protein conserved in bacteria K07192 - - 0.000000000000000000000000000000000000000000000000000000000000000002422 246.0
MMD2_k127_532607_0 DNA-binding transcription factor activity K07728 - - 0.0000000000000000000000000000000000000000000000000000000008763 213.0
MMD2_k127_532607_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000001173 166.0
MMD2_k127_532607_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000005941 162.0
MMD2_k127_532607_3 PFAM Glutamine amidotransferase class-I - - - 0.0000000000000000000000000000000000002209 149.0
MMD2_k127_532607_4 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000008819 138.0
MMD2_k127_532607_5 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000002969 134.0
MMD2_k127_532607_6 - - - - 0.0000000000000008092 91.0
MMD2_k127_5383657_1 phosphoesterase, PA-phosphatase related - - - 0.0000002198 59.0
MMD2_k127_5383657_2 DNA-templated transcription, initiation K03088 - - 0.00002723 54.0
MMD2_k127_5390164_0 lipase activity K01083,K11018,K12686,K15349,K21831 GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0016289,GO:0016290,GO:0016787,GO:0016788,GO:0016790,GO:0047617,GO:0052689 3.1.3.8 0.00000000000000000000009303 114.0
MMD2_k127_5410145_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001867 289.0
MMD2_k127_5410145_1 PFAM PKD domain containing protein - - - 0.0000000000005874 79.0
MMD2_k127_5410145_2 LamG domain protein jellyroll fold domain protein - - - 0.00002157 58.0
MMD2_k127_5416387_0 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000003035 242.0
MMD2_k127_5416387_1 - - - - 0.0000000000000008754 86.0
MMD2_k127_5416387_2 Pfam PF01910 - - - 0.00000003169 63.0
MMD2_k127_5416387_3 Reeler domain - - - 0.000003999 59.0
MMD2_k127_5442653_0 Fumarate reductase succinate dehydrogenase flavoprotein K00239 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 615.0
MMD2_k127_5442653_1 Fumarase C C-terminus K01679,K01744 - 4.2.1.2,4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 475.0
MMD2_k127_5442653_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000007543 252.0
MMD2_k127_5442653_3 COG0479 Succinate dehydrogenase fumarate reductase, Fe-S protein subunit K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000001501 218.0
MMD2_k127_5442653_4 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.000000000000000000000000000000000000000000000000000000000009122 216.0
MMD2_k127_5447037_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 545.0
MMD2_k127_5447037_1 4Fe-4S dicluster domain K00124 - - 0.000000000000000000009683 100.0
MMD2_k127_5470052_0 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000006218 141.0
MMD2_k127_5470052_1 cytochrome C oxidase subunit K02275 - 1.9.3.1 0.0000000000000000000000002441 121.0
MMD2_k127_5479861_0 Rhs family - - - 0.0000000000004078 83.0
MMD2_k127_549251_0 COGs COG3367 conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001335 252.0
MMD2_k127_549251_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000001769 184.0
MMD2_k127_549251_2 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000006701 173.0
MMD2_k127_5513844_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 578.0
MMD2_k127_5513844_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000007324 162.0
MMD2_k127_5513844_2 Acetyltransferase (GNAT) domain - - - 0.0001343 50.0
MMD2_k127_5513906_0 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000008597 156.0
MMD2_k127_5513906_1 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000000003466 95.0
MMD2_k127_5514231_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000002401 83.0
MMD2_k127_5515312_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000009155 252.0
MMD2_k127_5515312_1 Transcriptional regulator, ArsR family - - - 0.0000000000000000000000000000000000000000011 163.0
MMD2_k127_5515312_2 DNA binding protein K06930 - - 0.0000000000000000000000000001231 123.0
MMD2_k127_5515312_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000573 108.0
MMD2_k127_5521338_0 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000004101 186.0
MMD2_k127_5521338_1 amine dehydrogenase activity - - - 0.000001054 63.0
MMD2_k127_5521636_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008577 516.0
MMD2_k127_5521636_1 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000000003561 226.0
MMD2_k127_5521636_2 Belongs to the peptidase S8 family K17734 - - 0.000000000000000000000000000000000000000000000000000006919 215.0
MMD2_k127_5524597_0 Glycosyl hydrolases family 32 N-terminal domain - - - 0.0000000000000000000007848 113.0
MMD2_k127_5524597_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000001199 89.0
MMD2_k127_5524597_2 Belongs to the glycosyl hydrolase 32 family K01193 - 3.2.1.26 0.000002833 61.0
MMD2_k127_5525665_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 358.0
MMD2_k127_5525665_1 UPF0056 membrane protein K05595 - - 0.0000004715 59.0
MMD2_k127_5529981_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 382.0
MMD2_k127_5529981_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000001344 111.0
MMD2_k127_5529981_2 Bacterial Ig-like domain (group 3) K20276 - - 0.000000000000000000000001714 122.0
MMD2_k127_5530777_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000008592 244.0
MMD2_k127_5530777_1 ribosomal small subunit binding - - - 0.000001971 57.0
MMD2_k127_5530777_2 Protein of unknown function (DUF835) - - - 0.00000806 57.0
MMD2_k127_5542345_0 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 370.0
MMD2_k127_5542345_1 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000000000000003724 170.0
MMD2_k127_5542345_2 helicase superfamily c-terminal domain K03724 - - 0.00000000000000000000000000000000000001008 153.0
MMD2_k127_5542345_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000105 134.0
MMD2_k127_5542345_4 AAA-like domain K06915 - - 0.000000000000001446 78.0
MMD2_k127_5542345_5 Protein of unknown function (DUF357) K09728 - - 0.0002615 48.0
MMD2_k127_5556856_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 4.766e-266 858.0
MMD2_k127_5558732_0 Papain family cysteine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000009323 241.0
MMD2_k127_5559080_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 463.0
MMD2_k127_5559080_1 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000000001697 152.0
MMD2_k127_5559671_0 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 472.0
MMD2_k127_5559671_1 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 407.0
MMD2_k127_5559671_2 domain, Protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001532 289.0
MMD2_k127_5559671_3 COG1226 Kef-type K transport systems K10716 - - 0.00000000000000000000000000000000000000009378 167.0
MMD2_k127_5559671_4 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000001313 124.0
MMD2_k127_5559671_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000006907 119.0
MMD2_k127_5559671_6 Hemerythrin HHE cation binding domain - - - 0.0000000000001027 81.0
MMD2_k127_5559741_0 Domain of unknown function DUF11 - - - 0.0000000000007608 82.0
MMD2_k127_5559741_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000007722 63.0
MMD2_k127_5562014_0 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000007284 120.0
MMD2_k127_5562014_1 Immunoglobulin like K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.00003186 58.0
MMD2_k127_5566548_0 Belongs to the N(4) N(6)-methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 453.0
MMD2_k127_5566548_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 421.0
MMD2_k127_5566548_2 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 332.0
MMD2_k127_5566548_3 Putative undecaprenyl diphosphate synthase K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000001348 246.0
MMD2_k127_5566548_4 Glycosyl transferase 4-like - - - 0.000000000000000000000000000000000000001625 161.0
MMD2_k127_5566548_5 Thioredoxin - - - 0.000000000000000000000001919 109.0
MMD2_k127_5566548_6 Aldo/keto reductase family - - - 0.00000000000000000000001446 105.0
MMD2_k127_5566548_7 Belongs to the thioredoxin family K03671 - - 0.0000000000001637 75.0
MMD2_k127_5570677_0 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000000000000003833 156.0
MMD2_k127_5570677_1 cell redox homeostasis K12057,K22278 - 3.5.1.104 0.00000000000000643 89.0
MMD2_k127_5576752_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000009443 143.0
MMD2_k127_5576752_1 helix_turn_helix ASNC type - - - 0.00008506 49.0
MMD2_k127_5576864_0 Belongs to the sodium neurotransmitter symporter (SNF) (TC 2.A.22) family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005994 409.0
MMD2_k127_5592527_0 Isocitrate isopropylmalate dehydrogenase K05824 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0019878,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0047046,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.87 0.0000000000000000000000000000000000000001208 153.0
MMD2_k127_5593948_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000005489 78.0
MMD2_k127_5593948_1 Double zinc ribbon - - - 0.00001773 54.0
MMD2_k127_5596213_0 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 286.0
MMD2_k127_5596213_1 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000003291 233.0
MMD2_k127_5596213_2 Right handed beta helix region - - - 0.000425 54.0
MMD2_k127_5609589_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003572 388.0
MMD2_k127_5609589_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008971 301.0
MMD2_k127_5609589_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000001761 207.0
MMD2_k127_5609938_0 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000005736 177.0
MMD2_k127_5609938_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000006992 156.0
MMD2_k127_5609938_2 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.000000000000000000000000000001511 127.0
MMD2_k127_5609938_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000009264 93.0
MMD2_k127_5612725_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 614.0
MMD2_k127_5616120_0 Integrin alpha (beta-propellor repeats). - - - 0.0000000000000001681 94.0
MMD2_k127_5626207_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 331.0
MMD2_k127_5626207_1 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001363 276.0
MMD2_k127_5626207_2 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.000000000000000000000000000000000006499 148.0
MMD2_k127_5626207_3 SIS domain K08094 - 5.3.1.27 0.0000000000000000000000000003815 130.0
MMD2_k127_5626207_4 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000232 67.0
MMD2_k127_5627777_0 6-phosphogluconolactonase activity - - - 0.00000000000000000006499 104.0
MMD2_k127_5627777_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0001295 55.0
MMD2_k127_5629286_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 321.0
MMD2_k127_5629286_1 DNA binding K06930 - - 0.000000000000005126 85.0
MMD2_k127_5629286_2 Methyltransferase type 11 K03892 - - 0.00000000000002803 81.0
MMD2_k127_5632874_0 OmpA family - - - 0.000000225 64.0
MMD2_k127_5642666_0 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000001486 217.0
MMD2_k127_5642666_1 COG1230 Co Zn Cd efflux system component K16264 - - 0.000000000003369 68.0
MMD2_k127_5642666_2 EamA-like transporter family - - - 0.0000000000125 75.0
MMD2_k127_5680943_0 Tetratricopeptide repeat K12600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 534.0
MMD2_k127_5680943_1 TPR repeat-containing protein K07452 - - 0.00000000000000000000000000000000000000000000005898 197.0
MMD2_k127_5680943_2 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000004144 174.0
MMD2_k127_5680943_3 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000000000000000000000000008902 183.0
MMD2_k127_5680943_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000002015 111.0
MMD2_k127_5680943_5 Transcriptional regulator - - - 0.00000000000000000212 99.0
MMD2_k127_5680943_6 COG0457 FOG TPR repeat - - - 0.00000000000000006621 98.0
MMD2_k127_5680943_7 exosome subunit K07581 - - 0.000000001272 67.0
MMD2_k127_5698803_0 Si dkey-103j14.5 K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008333 278.0
MMD2_k127_5698803_1 SMART Integrin alpha beta-propellor repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000002247 237.0
MMD2_k127_5698803_2 Protein conserved in bacteria - - - 0.00000003616 68.0
MMD2_k127_5724320_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 364.0
MMD2_k127_5724320_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000001979 215.0
MMD2_k127_5724320_2 geranylgeranyl reductase - - - 0.0000000000000297 80.0
MMD2_k127_5729621_0 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001537 287.0
MMD2_k127_5729621_1 RNA-binding protein of the translin family K07477 - - 0.00000000000000000000000000000005158 136.0
MMD2_k127_5729621_2 Prismane/CO dehydrogenase family K00198 - 1.2.7.4 0.00000001644 55.0
MMD2_k127_5735619_0 ABC-type multidrug transport system ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 395.0
MMD2_k127_5735619_1 ABC-type multidrug transport system, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 344.0
MMD2_k127_5735619_2 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.00000000000000000000000000000000000000003706 165.0
MMD2_k127_5736298_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000295 277.0
MMD2_k127_5736298_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000001146 106.0
MMD2_k127_5760578_0 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 407.0
MMD2_k127_5760578_1 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000005266 191.0
MMD2_k127_5760578_2 ABC 3 transport family K09816 - - 0.00000000000000000000000000000000000000000001155 177.0
MMD2_k127_576730_0 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 323.0
MMD2_k127_576730_1 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000007902 130.0
MMD2_k127_576730_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00003657 46.0
MMD2_k127_5773846_0 glycoside hydrolase, family - - - 0.0000000000000000000000000000006667 140.0
MMD2_k127_5773846_1 Protein of unknown function DUF58 - - - 0.0000000000000001065 93.0
MMD2_k127_5773846_2 Transglutaminase/protease-like homologues K22452 - 2.3.2.13 0.0000000000001369 84.0
MMD2_k127_5775722_0 Required for chromosome condensation and partitioning K03529 - - 1.425e-241 789.0
MMD2_k127_5775722_1 chromosome segregation and condensation protein ScpA K05896 - - 0.00000000000000000000000000000000000000000001271 177.0
MMD2_k127_579140_0 NAD(P)H-binding - - - 0.00000000000000000000000000000000000000000000009902 177.0
MMD2_k127_579140_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000001033 169.0
MMD2_k127_579140_2 Involved in the binding of tRNA to the ribosomes K02946 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003877 157.0
MMD2_k127_579140_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000004037 96.0
MMD2_k127_579140_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000001198 64.0
MMD2_k127_58266_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 379.0
MMD2_k127_58266_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000003041 194.0
MMD2_k127_5858233_0 homolog of PrgY (pheromone shutdown protein) - - - 0.00000000000000000000000000000000001201 148.0
MMD2_k127_5858233_1 Belongs to the ompA family K20276 - - 0.0000000000000000000000000004702 127.0
MMD2_k127_5858233_2 domain, Protein - - - 0.0000000000000000124 90.0
MMD2_k127_5869641_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 7.001e-218 730.0
MMD2_k127_5869641_1 Thioredoxin domain K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 295.0
MMD2_k127_5869641_2 Domain of unknown function - - - 0.0000000000000000000000000000005313 141.0
MMD2_k127_5879224_0 Fibronectin type 3 domain K01637 - 4.1.3.1 0.0000000000000000000006013 111.0
MMD2_k127_5879224_1 PFAM PKD domain containing protein - - - 0.000000000003812 74.0
MMD2_k127_5879224_2 metallopeptidase activity - - - 0.000000001705 70.0
MMD2_k127_5879224_3 Pfam:DUF552 K09152 - - 0.000000001985 72.0
MMD2_k127_5908878_0 PFAM PKD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 387.0
MMD2_k127_5908878_1 PP-loop family K21947 - 2.8.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002207 283.0
MMD2_k127_5908878_2 Right handed beta helix region - - - 0.0000000000002893 83.0
MMD2_k127_5911835_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000004475 266.0
MMD2_k127_5911835_1 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000007115 166.0
MMD2_k127_5913333_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 432.0
MMD2_k127_5913333_1 thiamine pyrophosphate enzyme domain protein TPP-binding K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 389.0
MMD2_k127_5913333_2 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000003504 223.0
MMD2_k127_5913333_3 oxidoreductase subunit delta K00171 - 1.2.7.1 0.0000000000000000000000005824 106.0
MMD2_k127_5913333_4 Transcriptional regulator - - - 0.000000000000000000000001781 110.0
MMD2_k127_5955145_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 510.0
MMD2_k127_5955145_1 - - - - 0.0000000000000000000000000000000000002529 152.0
MMD2_k127_5955145_2 - - - - 0.000000000000000000000000000000005825 130.0
MMD2_k127_5967106_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 556.0
MMD2_k127_5967106_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000004914 189.0
MMD2_k127_5968028_0 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000001061 98.0
MMD2_k127_5968028_1 Alpha/beta hydrolase family K00627 - 2.3.1.12 0.000000000000000003667 90.0
MMD2_k127_5968028_2 Winged helix DNA-binding domain - - - 0.00000008567 58.0
MMD2_k127_6005361_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 388.0
MMD2_k127_6005361_1 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.00000000000000000000000000000005365 144.0
MMD2_k127_6008013_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 556.0
MMD2_k127_6008013_1 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000002057 149.0
MMD2_k127_6008013_2 Methyltransferase - - - 0.00000000000000000002733 100.0
MMD2_k127_6008013_3 CARDB - - - 0.0004179 53.0
MMD2_k127_6010877_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 1.688e-195 631.0
MMD2_k127_6012275_0 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000003091 216.0
MMD2_k127_6012275_1 Signal peptidase K13280 - 3.4.21.89 0.0000000000000000000000000000000000351 149.0
MMD2_k127_6012275_2 PFAM Tetratricopeptide - - - 0.0000000006149 70.0
MMD2_k127_6015617_0 PFAM Prenyltransferase squalene oxidase - - - 0.000000000000000000000000000000000004874 155.0
MMD2_k127_6017036_0 - K01992 - - 0.0000002029 63.0
MMD2_k127_6043420_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000001021 275.0
MMD2_k127_6043420_1 Copper amine oxidase N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000006211 216.0
MMD2_k127_6043420_2 Xylose isomerase-like TIM barrel - - - 0.00000000000004364 83.0
MMD2_k127_6046524_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703,K16792 - 4.2.1.114,4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 461.0
MMD2_k127_6046524_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006197 352.0
MMD2_k127_6046524_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704,K20453 - 4.2.1.33,4.2.1.35,4.2.1.85 0.0000000000000000000000008672 105.0
MMD2_k127_6054191_0 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001384 190.0
MMD2_k127_6054191_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000425 130.0
MMD2_k127_6054717_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 303.0
MMD2_k127_6054717_1 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0000000000000000000000000000000000000006644 169.0
MMD2_k127_6054717_2 Belongs to the glycosyl hydrolase 43 family K20276 - - 0.000000006321 63.0
MMD2_k127_6059285_0 COG0123 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000126 233.0
MMD2_k127_6059285_1 C-terminal domain of CHU protein family - - - 0.00000000000000000000000000000000000000000000000000000000000005344 245.0
MMD2_k127_6059285_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000004217 181.0
MMD2_k127_6059285_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000003419 171.0
MMD2_k127_6059285_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000002369 114.0
MMD2_k127_606567_0 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 497.0
MMD2_k127_6075838_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000002047 228.0
MMD2_k127_6075838_1 Glyoxalase-like domain K06996 - - 0.0000000000000000000000000000000000003033 145.0
MMD2_k127_6082876_0 metallopeptidase activity - - - 0.0000000000000000000000000000000000005645 160.0
MMD2_k127_6082876_1 Chlorophyllase enzyme - - - 0.0000001491 63.0
MMD2_k127_6084330_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 475.0
MMD2_k127_6084330_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000936 280.0
MMD2_k127_6084330_2 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000002505 92.0
MMD2_k127_6084330_3 binds to the 23S rRNA K02922 - - 0.000000000000008892 77.0
MMD2_k127_6086152_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000001713 184.0
MMD2_k127_6086152_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.00000003798 65.0
MMD2_k127_6108932_0 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004316 533.0
MMD2_k127_6113540_0 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006084 301.0
MMD2_k127_6113540_1 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000000002013 76.0
MMD2_k127_6113540_2 PFAM Endonuclease exonuclease phosphatase K07004 - - 0.00002502 56.0
MMD2_k127_6118389_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 444.0
MMD2_k127_6118389_1 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001351 261.0
MMD2_k127_6118389_2 Biotin carboxyl carrier protein K02160 - - 0.000000000000000000002095 94.0
MMD2_k127_6120603_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 559.0
MMD2_k127_6120603_1 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 340.0
MMD2_k127_6120603_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.0000000000000000000000000000000000000000000000000000000000000000000001088 267.0
MMD2_k127_6134967_0 Multicopper K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 574.0
MMD2_k127_6134967_1 Fibronectin type III domain - - - 0.0000000000003253 83.0
MMD2_k127_6147509_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000009611 200.0
MMD2_k127_6156649_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 522.0
MMD2_k127_6156649_1 4Fe-4S dicluster domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 384.0
MMD2_k127_6156649_2 PFAM methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000005923 199.0
MMD2_k127_6172079_0 aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 364.0
MMD2_k127_6172079_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000001692 173.0
MMD2_k127_6172079_2 Helix-turn-helix domain - - - 0.00000000000000000000001102 104.0
MMD2_k127_6172079_3 Helix-turn-helix domain - - - 0.00000000000000001708 88.0
MMD2_k127_6172079_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000003835 92.0
MMD2_k127_6177011_0 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 396.0
MMD2_k127_6177011_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000001162 154.0
MMD2_k127_6177011_2 AMMECR1 K09141 - - 0.0000000000000000000000000000000006646 133.0
MMD2_k127_6180219_0 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000000000000000000000000000000000000001905 193.0
MMD2_k127_6180219_1 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.000000000000000000000002553 117.0
MMD2_k127_6180219_2 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.0000000000125 68.0
MMD2_k127_6180219_3 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000002266 64.0
MMD2_k127_6188099_0 Belongs to the pyruvate kinase family K00873 GO:0001871,GO:0003674,GO:0003824,GO:0004743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006116,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0019693,GO:0019752,GO:0030246,GO:0030247,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:2001065 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 389.0
MMD2_k127_6188099_1 TOPRIM - - - 0.000000000000004205 86.0
MMD2_k127_6188099_2 Papain family cysteine protease - - - 0.000000000002356 82.0
MMD2_k127_6188099_3 Belongs to the UPF0235 family K09131 - - 0.0000000001118 71.0
MMD2_k127_6188099_5 Kelch motif - - - 0.0001358 56.0
MMD2_k127_6188099_6 PRC-barrel domain protein - - - 0.0004734 47.0
MMD2_k127_6188099_7 Cellulase N-terminal ig-like domain K20276 - - 0.0009301 53.0
MMD2_k127_6199138_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 1.922e-293 929.0
MMD2_k127_6206133_0 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000002416 135.0
MMD2_k127_6206133_1 Membrane - - - 0.00000000000000000000000000000003981 137.0
MMD2_k127_6208030_0 NapC/NirT cytochrome c family, N-terminal region K15876 - - 0.000000006988 68.0
MMD2_k127_6210539_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 6.172e-244 770.0
MMD2_k127_6210539_1 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.0000000000000000000000000000000000000000000000000000000008168 213.0
MMD2_k127_6210539_2 PFAM NAD-dependent epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000008072 185.0
MMD2_k127_6210539_3 nicotinamide-nucleotide adenylyltransferase K00952 - 2.7.7.1 0.000000000000000000000000000000000001178 159.0
MMD2_k127_6210539_4 Small multi-drug export protein - - - 0.000000000000000000000000004223 120.0
MMD2_k127_6210539_5 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.00000000000000000000006133 116.0
MMD2_k127_6210539_6 NUDIX domain - - - 0.00002424 55.0
MMD2_k127_6210539_7 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0002445 46.0
MMD2_k127_6221036_0 SMART ATPase, AAA type, core K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 341.0
MMD2_k127_6221036_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000001369 148.0
MMD2_k127_6221036_2 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000003703 63.0
MMD2_k127_6233277_0 acetyltransferase - - - 0.000000000000000000000000003048 121.0
MMD2_k127_6233277_1 OsmC-like protein - - - 0.000000000000000006069 95.0
MMD2_k127_6233277_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000005854 55.0
MMD2_k127_6236296_0 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000001357 188.0
MMD2_k127_6236296_1 Transcriptional regulator, TrmB - - - 0.000000000000203 76.0
MMD2_k127_6236296_2 Protease prsW family - - - 0.000000008188 64.0
MMD2_k127_6237493_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 441.0
MMD2_k127_6237493_1 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000003136 138.0
MMD2_k127_6237493_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000003113 83.0
MMD2_k127_6240681_0 ATPase (PilT family) K06865 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 314.0
MMD2_k127_6240681_1 LUD domain K00782 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009759 297.0
MMD2_k127_6240681_2 PFAM AIR synthase related protein K07123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001582 284.0
MMD2_k127_6240681_3 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000002748 194.0
MMD2_k127_6240681_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.00000000000000000000000000000000000000006724 157.0
MMD2_k127_6240681_5 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000003873 134.0
MMD2_k127_6240681_6 reductase K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000001466 123.0
MMD2_k127_6240681_7 PFAM VanZ - - - 0.0001412 49.0
MMD2_k127_6260019_0 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 323.0
MMD2_k127_6260019_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004659 284.0
MMD2_k127_6260019_2 - - - - 0.0000000000000000000001124 105.0
MMD2_k127_6260019_3 von willebrand factor, type A K20276 - - 0.000000000000005137 89.0
MMD2_k127_6260019_4 Tetratricopeptide repeat - - - 0.0005708 54.0
MMD2_k127_631614_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000001104 149.0
MMD2_k127_631614_1 - K01992 - - 0.00000002322 66.0
MMD2_k127_631614_2 Peptidase family C25 - - - 0.0001303 55.0
MMD2_k127_640187_0 Putative DNA-binding domain K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 428.0
MMD2_k127_640187_1 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008144 295.0
MMD2_k127_640187_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000002278 76.0
MMD2_k127_640187_4 - - - - 0.0000000000006657 78.0
MMD2_k127_640187_5 Belongs to the 'phage' integrase family K03733,K04763 - - 0.0000000000009261 82.0
MMD2_k127_640187_6 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000004882 79.0
MMD2_k127_649966_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000592 229.0
MMD2_k127_649966_1 COG0183 Acetyl-CoA acetyltransferase K00626,K00632 - 2.3.1.16,2.3.1.9 0.00000000000000000000000000000000000000000000000000003175 203.0
MMD2_k127_693234_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.427e-224 716.0
MMD2_k127_693234_1 Transcriptional regulator, ArsR family - - - 0.000000000000000948 89.0
MMD2_k127_697357_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 329.0
MMD2_k127_702008_0 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.000000000000000000000000000000000000000000000000000000000008504 221.0
MMD2_k127_702008_1 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.0000000000000000000000000000000000000000000001642 178.0
MMD2_k127_70902_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004091 446.0
MMD2_k127_733834_0 transferase activity, transferring glycosyl groups K01371 - 3.4.22.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009756 460.0
MMD2_k127_733834_1 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000004709 206.0
MMD2_k127_733834_2 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000008691 187.0
MMD2_k127_736628_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004074 334.0
MMD2_k127_736628_1 Bacterial Ig-like domain (group 3) K20276 - - 0.00002353 55.0
MMD2_k127_748826_0 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000002733 207.0
MMD2_k127_748826_1 Nodulation protein S (NodS) - - - 0.0000000000000003084 91.0
MMD2_k127_748826_2 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000049,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006450,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0065007,GO:0065008,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.7.7.87 0.000000000003065 76.0
MMD2_k127_748826_3 SMART Parallel beta-helix repeat - - - 0.00000000008877 76.0
MMD2_k127_748826_4 TIGRFAM Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000008938 66.0
MMD2_k127_748826_5 PFAM Major Facilitator Superfamily - - - 0.00069 52.0
MMD2_k127_752505_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K03177,K11131 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000009811 251.0
MMD2_k127_752505_1 epimerase - - - 0.0000000000000000000000000000000000000000000000000006652 192.0
MMD2_k127_757064_0 Protein of unknown function (DUF835) - - - 0.0000134 58.0
MMD2_k127_757064_1 Squalene--hopene cyclase K17811 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009267,GO:0009605,GO:0009607,GO:0009975,GO:0009987,GO:0009991,GO:0010350,GO:0016101,GO:0016102,GO:0016114,GO:0016853,GO:0016872,GO:0019637,GO:0031667,GO:0031668,GO:0031669,GO:0033385,GO:0033554,GO:0035439,GO:0035440,GO:0042594,GO:0043167,GO:0043169,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044419,GO:0046872,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0071496,GO:0071704,GO:0075136,GO:1901576 5.5.1.16 0.0002146 48.0
MMD2_k127_75925_0 PFAM PKD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 368.0
MMD2_k127_75925_1 NADP oxidoreductase coenzyme F420-dependent - - - 0.0000000000000000000000000000000000000000000000000004698 192.0
MMD2_k127_75925_2 Bacterio-opsin activator HTH K06930,K06988 - 1.5.1.40 0.0000000000000000000000000000000000006706 149.0
MMD2_k127_75925_3 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000009902 120.0
MMD2_k127_75925_4 Fungal trichothecene efflux pump (TRI12) - - - 0.00000000000000000002979 94.0
MMD2_k127_796145_0 archaeal coiled-coil protein - - - 0.00000000000000000000000002663 120.0
MMD2_k127_796145_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0002845 52.0
MMD2_k127_80179_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003416 546.0
MMD2_k127_80179_1 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 306.0
MMD2_k127_821013_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000054 68.0
MMD2_k127_823479_0 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001983 266.0
MMD2_k127_823479_1 PFAM Xylose isomerase domain protein TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000002099 166.0
MMD2_k127_823479_10 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0007178 45.0
MMD2_k127_823479_2 Psort location Cytoplasmic, score 8.87 - - - 0.000000000000000000000000006073 119.0
MMD2_k127_823479_3 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000002691 121.0
MMD2_k127_823479_4 addiction module toxin, RelE StbE family - - - 0.000000000000000000005083 98.0
MMD2_k127_823479_5 Zn_pept K08781 GO:0003674,GO:0003824,GO:0004180,GO:0004181,GO:0005575,GO:0005576,GO:0005615,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044421,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.17.1 0.0000000000000000001087 103.0
MMD2_k127_823479_6 Protein of unknown function (DUF2683) - - - 0.00000000000000927 76.0
MMD2_k127_823479_7 - - - - 0.0000001265 63.0
MMD2_k127_823479_8 regulator of chromosome condensation, RCC1 - - - 0.000002217 62.0
MMD2_k127_823479_9 CARDB - - - 0.0003415 54.0
MMD2_k127_83048_0 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 451.0
MMD2_k127_83048_1 PFAM Bacterial transcription activator, effector binding - - - 0.0000000001421 70.0
MMD2_k127_83048_2 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0006228 53.0
MMD2_k127_851256_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 316.0
MMD2_k127_851256_1 PFAM PKD domain containing protein - - - 0.00000000000000000000001946 117.0
MMD2_k127_851256_2 metallopeptidase activity K01081,K01183,K20276 - 3.1.3.5,3.2.1.14 0.00000000004544 77.0
MMD2_k127_853780_0 self proteolysis K21449 - - 0.000000000000000000000000000001139 143.0
MMD2_k127_853780_1 DnaB-like helicase C terminal domain - - - 0.00000000000002598 78.0
MMD2_k127_853780_2 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000005362 79.0
MMD2_k127_869149_0 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000004785 226.0
MMD2_k127_869149_1 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000002305 191.0
MMD2_k127_869149_2 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000007919 171.0
MMD2_k127_870957_0 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 400.0
MMD2_k127_870957_1 Met-10+ like-protein K07055 - 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000008929 217.0
MMD2_k127_870957_2 metallopeptidase activity - - - 0.00000000008365 74.0
MMD2_k127_870957_3 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000251 59.0
MMD2_k127_874979_0 DEAD-box RNA helicase involved in various cellular processes at low temperature, including ribosome biogenesis, mRNA degradation and translation initiation K05592 - 3.6.4.13 0.000000000000000000000000000000000000000187 155.0
MMD2_k127_878415_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 472.0
MMD2_k127_878415_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008675 390.0
MMD2_k127_878415_2 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000008461 70.0
MMD2_k127_890178_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004468 400.0
MMD2_k127_890178_1 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006303 274.0
MMD2_k127_890178_2 Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000004135 258.0
MMD2_k127_890178_3 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000006986 203.0
MMD2_k127_890178_4 PFAM acylneuraminate cytidylyltransferase K00983 - 2.7.7.43 0.0000000000000000000000000000000000000000000003915 177.0
MMD2_k127_890178_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000003905 170.0
MMD2_k127_890178_6 PFAM Nitrous oxide-stimulated promoter - - - 0.00000000000000000000000000000000002355 137.0
MMD2_k127_893480_0 FMN binding K03809 - 1.6.5.2 0.000000000000000000000000000000000000000004277 167.0
MMD2_k127_893480_1 RHS Repeat - - - 0.0000000002108 74.0
MMD2_k127_893480_2 Major facilitator Superfamily - - - 0.000791 51.0
MMD2_k127_905995_0 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002714 273.0
MMD2_k127_905995_1 LamG domain protein jellyroll fold domain protein K12567 - 2.7.11.1 0.000000000000000000000000000000000000000000004324 190.0
MMD2_k127_905995_2 myosin light chain kinase activity K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.000000000000000000000000000000000001552 160.0
MMD2_k127_908457_0 Belongs to the ABC transporter superfamily K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 293.0
MMD2_k127_908457_1 Binding-protein-dependent transport system inner membrane component K02046 - - 0.000000000000000000000001148 108.0
MMD2_k127_908457_2 Nucleotidyltransferase domain - - - 0.000001569 58.0
MMD2_k127_912142_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 333.0
MMD2_k127_912142_1 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008774 271.0
MMD2_k127_931246_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005055 251.0
MMD2_k127_931246_1 TIGRFAM F420-dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000006037 209.0
MMD2_k127_931246_2 PFAM PfkB domain protein K00852,K16328 - 2.7.1.15,2.7.1.83 0.00000000000000000000000000000004606 138.0
MMD2_k127_93866_0 AIR synthase related protein, C-terminal domain K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007579 361.0
MMD2_k127_93866_1 TIGRFAM conserved repeat domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007526 323.0
MMD2_k127_941781_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 421.0
MMD2_k127_941781_1 Glycosyl transferase 4-like domain - - - 0.0000000000000002487 92.0
MMD2_k127_941781_2 PFAM PUA domain K00390 - 1.8.4.10,1.8.4.8 0.000000000005436 67.0
MMD2_k127_941781_3 RDD family - - - 0.00000000289 68.0
MMD2_k127_986995_0 acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 322.0
MMD2_k127_986995_1 COG0095 Lipoate-protein ligase A K03800 GO:0003674,GO:0005488,GO:0005504,GO:0005575,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0008289,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0031405,GO:0031406,GO:0032991,GO:0033293,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0048037,GO:0050662,GO:0051604,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901681 6.3.1.20 0.000000000000000000000000000000000002252 147.0
MMD2_k127_986995_2 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000003913 58.0