Overview

ID MAG02370
Name MMD2_bin.36
Sample SMP0059
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Anaerolineae
Order Anaerolineales
Family RBG-16-64-43
Genus RBG-16-64-43
Species
Assembly information
Completeness (%) 80.69
Contamination (%) 1.05
GC content (%) 66.0
N50 (bp) 10,929
Genome size (bp) 1,763,563

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1579

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1000777_0 PFAM Transketolase central region K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 445.0
MMD2_k127_1000777_1 Dehydrogenase E1 component K00166 - 1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 331.0
MMD2_k127_1000777_2 e3 binding domain K00658,K09699 - 2.3.1.168,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 332.0
MMD2_k127_1000777_3 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
MMD2_k127_1001662_0 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 471.0
MMD2_k127_1001662_1 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003801 361.0
MMD2_k127_1001662_2 Bacterial sugar transferase - - - 0.00000000000000001157 86.0
MMD2_k127_1035925_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 440.0
MMD2_k127_1035925_2 PFAM Tetratricopeptide repeat - - - 0.000000000001436 78.0
MMD2_k127_1036939_0 PFAM AAA-4 family protein K02444,K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 468.0
MMD2_k127_1036939_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.00000000000000009476 84.0
MMD2_k127_1052049_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1062.0
MMD2_k127_1073830_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.697e-255 797.0
MMD2_k127_1073830_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.969e-246 766.0
MMD2_k127_1073830_10 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.00000000000000000000000000000000000000000000000000119 203.0
MMD2_k127_1073830_11 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001249 189.0
MMD2_k127_1073830_12 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000000000000000001366 182.0
MMD2_k127_1073830_13 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000005105 163.0
MMD2_k127_1073830_14 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000002152 149.0
MMD2_k127_1073830_15 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000008337 160.0
MMD2_k127_1073830_16 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000001486 146.0
MMD2_k127_1073830_17 chromosome segregation K03497 - - 0.0000000000000000000000000000000009421 146.0
MMD2_k127_1073830_18 SMART helix-turn-helix domain protein K15539 - - 0.000000000000000000000000000000001373 143.0
MMD2_k127_1073830_19 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000001079 128.0
MMD2_k127_1073830_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 605.0
MMD2_k127_1073830_21 Copper binding proteins, plastocyanin/azurin family - - - 0.000000004642 64.0
MMD2_k127_1073830_22 DinB superfamily - - - 0.0002373 50.0
MMD2_k127_1073830_3 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 528.0
MMD2_k127_1073830_4 Cell division protein FtsA K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004899 342.0
MMD2_k127_1073830_5 Belongs to the 'phage' integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 326.0
MMD2_k127_1073830_6 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 310.0
MMD2_k127_1073830_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002628 306.0
MMD2_k127_1073830_8 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000958 248.0
MMD2_k127_1073830_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000004216 199.0
MMD2_k127_107655_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002252 479.0
MMD2_k127_107655_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000000000001642 195.0
MMD2_k127_107655_2 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.000000000000000000000000000000000000001872 153.0
MMD2_k127_107655_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000002613 151.0
MMD2_k127_107655_4 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000002573 132.0
MMD2_k127_107655_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000693 120.0
MMD2_k127_107655_6 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000001488 115.0
MMD2_k127_107655_7 Belongs to the UPF0109 family K06960 - - 0.0000000000005724 75.0
MMD2_k127_1083804_0 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 507.0
MMD2_k127_1083804_2 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 389.0
MMD2_k127_1083804_3 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000008688 176.0
MMD2_k127_1083804_4 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000001471 169.0
MMD2_k127_1083804_6 COG2335, Secreted and surface protein containing fasciclin-like repeats - - - 0.00000000000000000003194 100.0
MMD2_k127_1087598_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 406.0
MMD2_k127_1087598_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005992 368.0
MMD2_k127_1087598_2 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 351.0
MMD2_k127_1087598_3 PFAM Exonuclease, RNase T and DNA polymerase III K02342,K03722 - 2.7.7.7,3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000004914 237.0
MMD2_k127_1087598_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000004347 63.0
MMD2_k127_1089498_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 390.0
MMD2_k127_1089498_1 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.00000000000005964 81.0
MMD2_k127_1089498_2 Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine K04069 - 1.97.1.4 0.000005798 51.0
MMD2_k127_1089498_3 Phosphopantetheine attachment site - - - 0.0000926 49.0
MMD2_k127_1159724_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009168 439.0
MMD2_k127_1159724_1 Phosphotransferase K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000009978 264.0
MMD2_k127_1159724_2 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000005815 116.0
MMD2_k127_1159724_3 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000009157 77.0
MMD2_k127_1159724_4 ABC transporter K10112 - - 0.000000000001682 68.0
MMD2_k127_1179450_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 372.0
MMD2_k127_1179450_1 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 325.0
MMD2_k127_1179450_2 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 300.0
MMD2_k127_1179450_3 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000001221 158.0
MMD2_k127_1179450_4 ABC-2 type transporter K01992 - - 0.000000000000000000000002194 108.0
MMD2_k127_1232835_0 Transcriptional regulator of aromatic amino acids metabolism K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 332.0
MMD2_k127_1232835_1 PFAM Rhomboid family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003035 277.0
MMD2_k127_1232835_2 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003267 249.0
MMD2_k127_1232835_3 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000006347 219.0
MMD2_k127_1232835_4 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000001409 179.0
MMD2_k127_1232835_6 PFAM TadE family protein K12287 - - 0.000000000000000000000002325 118.0
MMD2_k127_1232835_7 PFAM TadE family protein K12287 - - 0.0000000000000000001965 103.0
MMD2_k127_1232835_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000001872 66.0
MMD2_k127_1232835_9 TadE-like protein - - - 0.00001538 55.0
MMD2_k127_1238270_0 PFAM major facilitator superfamily MFS_1 - - - 1.328e-196 622.0
MMD2_k127_1238270_1 ADP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 597.0
MMD2_k127_1238270_10 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000000000002494 124.0
MMD2_k127_1238270_11 PFAM Vitamin B12 dependent methionine synthase, activation - - - 0.00000000000002155 81.0
MMD2_k127_1238270_2 ADP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 525.0
MMD2_k127_1238270_3 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003165 422.0
MMD2_k127_1238270_4 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 410.0
MMD2_k127_1238270_5 family 4 K01222 - 3.2.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 346.0
MMD2_k127_1238270_6 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001605 277.0
MMD2_k127_1238270_7 C4-dicarboxylate anaerobic carrier - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001079 262.0
MMD2_k127_1238270_8 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000007471 251.0
MMD2_k127_1238270_9 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000003441 189.0
MMD2_k127_1240209_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 1.387e-262 819.0
MMD2_k127_1240209_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 500.0
MMD2_k127_1240209_2 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 498.0
MMD2_k127_1240209_3 PFAM PSP1 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 321.0
MMD2_k127_1240209_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002919 310.0
MMD2_k127_1240209_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K03615 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 304.0
MMD2_k127_1240209_6 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000008274 243.0
MMD2_k127_1240209_7 - - - - 0.00000000000000000000000000003997 129.0
MMD2_k127_1240209_8 FeS assembly protein IscX - - - 0.000000001079 63.0
MMD2_k127_1240209_9 Haloacid dehalogenase-like hydrolase K07025 - - 0.000004853 51.0
MMD2_k127_1249584_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 584.0
MMD2_k127_1249584_1 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 308.0
MMD2_k127_1249584_2 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 0.00000000000000000000000000000000000000000000000000001407 193.0
MMD2_k127_1249584_3 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000000000000000001502 172.0
MMD2_k127_1249584_4 Nitroreductase family - - - 0.0000000000000000000000000000000000000001428 157.0
MMD2_k127_1309419_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 533.0
MMD2_k127_1309419_1 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002647 489.0
MMD2_k127_1309419_10 Cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 294.0
MMD2_k127_1309419_11 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002164 285.0
MMD2_k127_1309419_12 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000003067 242.0
MMD2_k127_1309419_13 PFAM Methicillin resistance protein - - - 0.0000000000000000000000000000000000000000004886 161.0
MMD2_k127_1309419_14 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000006906 133.0
MMD2_k127_1309419_16 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0042802,GO:0043093,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000002272 111.0
MMD2_k127_1309419_2 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002902 475.0
MMD2_k127_1309419_3 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 455.0
MMD2_k127_1309419_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 413.0
MMD2_k127_1309419_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 398.0
MMD2_k127_1309419_6 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 401.0
MMD2_k127_1309419_7 Pyridoxal-phosphate dependent enzyme K17950 - 4.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 351.0
MMD2_k127_1309419_8 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 342.0
MMD2_k127_1309419_9 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 356.0
MMD2_k127_1315192_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1120.0
MMD2_k127_1315192_1 SMART phosphoesterase PHP domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 559.0
MMD2_k127_1315192_2 acetyltransferase K00950,K03789,K03823 - 2.3.1.128,2.3.1.183,2.7.6.3 0.000000000000000000000000000000000000000171 160.0
MMD2_k127_1315192_3 acetyltransferase K03826 - - 0.0000000000000000000000000000004314 128.0
MMD2_k127_1315192_4 Probable molybdopterin binding domain - - - 0.00000000000000000000000000005333 117.0
MMD2_k127_1315192_5 Belongs to the small heat shock protein (HSP20) family - - - 0.000000000000000000000001119 109.0
MMD2_k127_1315192_6 response regulator K03413,K07719 - - 0.00000000000000000000003156 105.0
MMD2_k127_1333141_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.91e-298 937.0
MMD2_k127_1333141_1 PFAM cytoplasmic peptidoglycan synthetase domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 500.0
MMD2_k127_1333141_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000003822 154.0
MMD2_k127_1333141_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000003042 115.0
MMD2_k127_1360436_0 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 1.054e-228 726.0
MMD2_k127_1360436_1 Belongs to the RtcB family K14415 - 6.5.1.3 3.773e-219 689.0
MMD2_k127_1360436_10 Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.000000003505 64.0
MMD2_k127_1360436_11 Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization K03610 - - 0.00000004833 63.0
MMD2_k127_1360436_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.412e-196 625.0
MMD2_k127_1360436_3 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 494.0
MMD2_k127_1360436_4 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007531 424.0
MMD2_k127_1360436_5 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 386.0
MMD2_k127_1360436_6 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 368.0
MMD2_k127_1360436_7 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000000000000000000000000000000000000000000000000000003883 239.0
MMD2_k127_1360436_8 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000001412 188.0
MMD2_k127_1360436_9 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000000000006018 115.0
MMD2_k127_1377735_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 5.659e-212 672.0
MMD2_k127_1377735_1 PFAM nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 409.0
MMD2_k127_1377735_10 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000002196 156.0
MMD2_k127_1377735_11 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00125 - 1.17.1.9 0.0000000000000000000000000002139 128.0
MMD2_k127_1377735_12 spore germination K03605 - - 0.00000000000000000002094 97.0
MMD2_k127_1377735_13 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000002036 61.0
MMD2_k127_1377735_14 PBS lyase HEAT-like repeat - - - 0.0000005359 62.0
MMD2_k127_1377735_2 Formate/nitrite transporter K06212 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002888 379.0
MMD2_k127_1377735_3 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 370.0
MMD2_k127_1377735_4 Trimethylamine methyltransferase (MTTB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 343.0
MMD2_k127_1377735_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 329.0
MMD2_k127_1377735_6 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 304.0
MMD2_k127_1377735_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000706 278.0
MMD2_k127_1377735_8 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000005769 201.0
MMD2_k127_1377735_9 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000001982 179.0
MMD2_k127_145480_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.0000000000000000000000000000000000000000000000000000000000008742 216.0
MMD2_k127_145480_2 Methyltransferase type 12 - - - 0.000000000000000000000000000000000000000000000007854 181.0
MMD2_k127_145480_3 YacP-like NYN domain K06962 - - 0.00000000000000000000002858 106.0
MMD2_k127_145534_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 560.0
MMD2_k127_145534_1 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003384 316.0
MMD2_k127_145534_2 protein deglycation K05520 - 3.5.1.124 0.000000000000000000000000000000000000000000000000004132 187.0
MMD2_k127_145534_3 PHP-associated - - - 0.00000000000000000000000000000000000003082 153.0
MMD2_k127_145534_4 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000003686 51.0
MMD2_k127_1484771_0 ATPases associated with a variety of cellular activities K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 375.0
MMD2_k127_1484771_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 369.0
MMD2_k127_1484771_2 Alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 361.0
MMD2_k127_1484771_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 297.0
MMD2_k127_1484771_4 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007473 284.0
MMD2_k127_1484771_5 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000731 153.0
MMD2_k127_1484771_6 PFAM secretion protein HlyD family protein K01993 - - 0.000000000000000000000000000000000000001052 164.0
MMD2_k127_1484771_7 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.0000000000000000000000000000000000002452 143.0
MMD2_k127_1484771_8 transcriptional regulator - - - 0.00000000000000000000000000000005161 132.0
MMD2_k127_1484771_9 - - - - 0.0000000000000000001504 94.0
MMD2_k127_1487730_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.809e-307 958.0
MMD2_k127_1487730_1 Binding-protein-dependent transport system inner membrane component K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 557.0
MMD2_k127_1487730_2 Bacterial extracellular solute-binding protein K02064 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 444.0
MMD2_k127_1487730_3 TOBE domain K02062,K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 369.0
MMD2_k127_1487730_4 PFAM Thiamin pyrophosphokinase, catalytic region K00949 - 2.7.6.2 0.000000000000000000000000000000000000000000002025 173.0
MMD2_k127_1487730_5 Protein of unknown function (DUF402) K07586 - - 0.0000000000000000007247 95.0
MMD2_k127_1487730_6 AI-2E family transporter - - - 0.000000003884 65.0
MMD2_k127_150280_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 352.0
MMD2_k127_150280_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000002588 254.0
MMD2_k127_150280_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000000002322 190.0
MMD2_k127_150280_3 Protein of unknown function (DUF4230) - - - 0.0000000000000000000000000000000002671 142.0
MMD2_k127_1572748_0 ATPase AAA-2 domain protein K03696 - - 5.334e-314 988.0
MMD2_k127_1572748_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 593.0
MMD2_k127_1572748_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 468.0
MMD2_k127_1572748_3 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000006303 115.0
MMD2_k127_1572748_4 Transposase IS200 like - - - 0.00000000000000000000001312 104.0
MMD2_k127_1572748_5 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000007952 100.0
MMD2_k127_1585310_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 1.818e-250 781.0
MMD2_k127_1585310_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.473e-221 701.0
MMD2_k127_1585310_10 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000003098 184.0
MMD2_k127_1585310_11 Alpha beta hydrolase - - - 0.000000000000000000000000000000001648 139.0
MMD2_k127_1585310_12 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000002472 123.0
MMD2_k127_1585310_13 Belongs to the acetyltransferase family. ArgA subfamily K00537,K00619,K07755 - 1.20.4.1,2.1.1.137,2.3.1.1 0.000000000000000000006899 98.0
MMD2_k127_1585310_14 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000005462 73.0
MMD2_k127_1585310_15 cell adhesion K20276 - - 0.00000001963 66.0
MMD2_k127_1585310_16 - - - - 0.00003602 48.0
MMD2_k127_1585310_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.396e-218 687.0
MMD2_k127_1585310_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 491.0
MMD2_k127_1585310_4 PFAM acyl-CoA dehydrogenase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 422.0
MMD2_k127_1585310_5 acetyl-CoA carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000844 408.0
MMD2_k127_1585310_6 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 339.0
MMD2_k127_1585310_7 PFAM Alcohol dehydrogenase, zinc-binding K00001 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 337.0
MMD2_k127_1585310_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005748 269.0
MMD2_k127_1585310_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001709 243.0
MMD2_k127_1661406_0 Polynucleotide adenylyltransferase region K00974 - 2.7.7.72 6.973e-250 803.0
MMD2_k127_1661406_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 611.0
MMD2_k127_1661406_10 Protein of unknown function (DUF2892) K03671 - - 0.0000000000000000000000000000000000001368 147.0
MMD2_k127_1661406_11 NnrU protein K21310 - 2.1.1.334 0.00000000000000000000000000007845 123.0
MMD2_k127_1661406_12 PFAM peptidase M14, carboxypeptidase A - - - 0.00000000000000000000000000015 128.0
MMD2_k127_1661406_13 PFAM pentapeptide repeat protein - - - 0.0000000000000000000000371 104.0
MMD2_k127_1661406_14 Protein of unknown function (DUF2892) - - - 0.0000000000000000001077 93.0
MMD2_k127_1661406_15 positive regulation of macromolecule biosynthetic process K03973 - - 0.0000000000000000005269 93.0
MMD2_k127_1661406_16 Putative zinc-finger - - - 0.0000000000000002594 81.0
MMD2_k127_1661406_17 - - - - 0.000000000008197 74.0
MMD2_k127_1661406_2 PFAM VWA containing CoxE family protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008311 475.0
MMD2_k127_1661406_3 PFAM ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 438.0
MMD2_k127_1661406_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004238 445.0
MMD2_k127_1661406_5 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 349.0
MMD2_k127_1661406_6 Peptidase_C39 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 340.0
MMD2_k127_1661406_7 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000008486 239.0
MMD2_k127_1661406_8 PFAM sigma-70 region 2 domain protein K03088 - - 0.000000000000000000000000000000000000000000000000000004808 196.0
MMD2_k127_1661406_9 acetyltransferase - - - 0.0000000000000000000000000000000000000000003097 163.0
MMD2_k127_1662618_0 Domain present in PSD-95, Dlg, and ZO-1/2. K04771,K08070 - 1.3.1.74,3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 294.0
MMD2_k127_1662618_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000002237 216.0
MMD2_k127_1662618_2 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000008218 171.0
MMD2_k127_1662618_3 Diguanylate cyclase - - - 0.000672 51.0
MMD2_k127_16734_0 PFAM band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 419.0
MMD2_k127_16734_1 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000386 424.0
MMD2_k127_16734_10 Ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031365,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.128 0.00000000000009512 78.0
MMD2_k127_16734_2 galactokinase activity K00849 - 2.7.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 322.0
MMD2_k127_16734_3 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007062 282.0
MMD2_k127_16734_4 PFAM diacylglycerol kinase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001867 276.0
MMD2_k127_16734_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000154 216.0
MMD2_k127_16734_6 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000002868 203.0
MMD2_k127_16734_7 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K07025,K20866 - 3.1.3.10 0.000000000000000000000000000000000000000003858 171.0
MMD2_k127_16734_8 Helicase conserved C-terminal domain - - - 0.0000000000000000000000000000000000000168 163.0
MMD2_k127_16734_9 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.00000000000000000135 91.0
MMD2_k127_1675184_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 496.0
MMD2_k127_1675184_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 421.0
MMD2_k127_1675184_2 NAD synthase K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 415.0
MMD2_k127_1675184_3 Transmembrane secretion effector K08225 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 402.0
MMD2_k127_1675184_4 PFAM Shikimate quinate 5-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 378.0
MMD2_k127_1675184_5 molybdenum cofactor guanylyltransferase activity K03752,K13818 GO:0003674,GO:0003824,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000001193 244.0
MMD2_k127_1675184_6 phosphatidate phosphatase activity K01096,K19302 - 3.1.3.27,3.1.3.4,3.1.3.81,3.6.1.27 0.0000000000000000000000000000000000000000001672 166.0
MMD2_k127_1675184_7 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000004438 101.0
MMD2_k127_1687844_0 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 583.0
MMD2_k127_1687844_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005156 304.0
MMD2_k127_1792136_0 ABC-type polysaccharide polyol phosphate transport system ATPase component K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 321.0
MMD2_k127_1792136_1 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 301.0
MMD2_k127_1792136_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000005469 215.0
MMD2_k127_1826102_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.987e-280 874.0
MMD2_k127_1826102_1 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 513.0
MMD2_k127_1826102_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 362.0
MMD2_k127_1826102_3 N-4 methylation of cytosine K00590 - 2.1.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 368.0
MMD2_k127_1826102_4 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001726 259.0
MMD2_k127_1826102_5 TIGRFAM lipid kinase, YegS Rv2252 BmrU family - - - 0.00000000000000000000000000000000000000000002912 174.0
MMD2_k127_1826102_6 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000563 112.0
MMD2_k127_1826102_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000001164 111.0
MMD2_k127_1826102_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03075 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0022857,GO:0022884,GO:0031522,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044464,GO:0045047,GO:0045184,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000006362 68.0
MMD2_k127_1834591_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 455.0
MMD2_k127_1834591_1 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 370.0
MMD2_k127_1834591_2 PFAM ABC transporter related K02049,K15555,K15578 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 302.0
MMD2_k127_1834591_3 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000001415 199.0
MMD2_k127_1850918_0 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004977 607.0
MMD2_k127_1850918_1 Part of an ABC transporter complex involved in carbohydrate import. Could be involved in ribose, galactose and or methyl galactoside import. Responsible for energy coupling to the transport system K02056,K10441,K10542,K10545,K17204,K17215 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 440.0
MMD2_k127_1850918_2 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 309.0
MMD2_k127_1850918_3 catechol 2,3-dioxygenase activity K00446,K07104 - 1.13.11.2 0.000000000000000000000000009498 116.0
MMD2_k127_1882198_0 PFAM ABC transporter related K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002714 614.0
MMD2_k127_1882198_1 phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002677 252.0
MMD2_k127_1882198_2 Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000000000000000000000000000000000001635 241.0
MMD2_k127_1882198_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000002001 223.0
MMD2_k127_1882198_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0000000000000000000000000000000000000000000000000000001217 200.0
MMD2_k127_1882198_5 ECF-type riboflavin transporter, S component K16924 - - 0.000000000000000000000000000000000004719 149.0
MMD2_k127_1882198_6 - - - - 0.0000000007301 70.0
MMD2_k127_1911202_0 PFAM HD domain - - - 0.000000000000000000000000000000000000000000000000000007831 209.0
MMD2_k127_1911202_1 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000002302 183.0
MMD2_k127_1911202_2 Adenosine specific kinase K09129 - - 0.000000000000000000000000003035 112.0
MMD2_k127_1956251_0 Catalyzes the synthesis of activated sulfate K00958 - 2.7.7.4 2.933e-266 831.0
MMD2_k127_1956251_1 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 509.0
MMD2_k127_1956251_10 amino acid - - - 0.00000000000000000000000000000000000001064 164.0
MMD2_k127_1956251_11 glycosyl transferase group 1 - - - 0.00000000000000000000000000000003056 140.0
MMD2_k127_1956251_12 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000002826 128.0
MMD2_k127_1956251_13 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000007518 105.0
MMD2_k127_1956251_2 TIGRFAM galactose-1-phosphate uridylyltransferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 428.0
MMD2_k127_1956251_3 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005959 411.0
MMD2_k127_1956251_4 PFAM Metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 297.0
MMD2_k127_1956251_5 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003656 286.0
MMD2_k127_1956251_6 PFAM Diacylglycerol kinase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004622 257.0
MMD2_k127_1956251_7 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000006465 230.0
MMD2_k127_1956251_8 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000001987 203.0
MMD2_k127_1956251_9 - - - - 0.000000000000000000000000000000000000000000000000001367 194.0
MMD2_k127_1985392_10 PFAM Sporulation and spore germination - - - 0.000002093 60.0
MMD2_k127_1985392_11 - - - - 0.000002772 51.0
MMD2_k127_1985392_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000004962 234.0
MMD2_k127_1985392_3 - - - - 0.00000000000000000000000000000000000000000000000000000000002499 215.0
MMD2_k127_1985392_4 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000008973 198.0
MMD2_k127_1985392_5 Cyclophilin-like K09143 - - 0.000000000000000000000000002218 115.0
MMD2_k127_1985392_6 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000001537 111.0
MMD2_k127_1985392_7 ACT domain - - - 0.000000000000000000000001781 110.0
MMD2_k127_1985392_9 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000001529 83.0
MMD2_k127_1991235_0 PFAM Enoyl-CoA hydratase isomerase K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 553.0
MMD2_k127_1991235_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 537.0
MMD2_k127_1991235_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 289.0
MMD2_k127_1991235_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001846 264.0
MMD2_k127_1991235_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000002669 165.0
MMD2_k127_1991235_5 Sterol-binding domain protein - - - 0.000000000000000005761 87.0
MMD2_k127_1997551_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1536.0
MMD2_k127_1997551_1 Responsible for synthesis of pseudouridine from uracil K06180 GO:0000154,GO:0000455,GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 354.0
MMD2_k127_1997551_2 Threonyl alanyl tRNA synthetase SAD K07050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 291.0
MMD2_k127_1997551_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000005001 155.0
MMD2_k127_2066781_0 Kinase/pyrophosphorylase K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000001452 216.0
MMD2_k127_2066781_1 membrane - - - 0.00000000000000000000000000000000000000008248 162.0
MMD2_k127_2066781_2 COG2226 Methylase involved in ubiquinone menaquinone biosynthesis K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000002113 128.0
MMD2_k127_2066781_3 - - - - 0.0000000000000000000000000002643 125.0
MMD2_k127_2066781_4 methyltransferase - - - 0.00000000000000000000001696 104.0
MMD2_k127_2066781_5 PspC domain - - - 0.0000000000000000001182 94.0
MMD2_k127_2066781_6 - - - - 0.0000000000000000001513 96.0
MMD2_k127_2066781_7 N-terminal domain of toast_rack, DUF2154 - - - 0.0000009457 60.0
MMD2_k127_208204_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1198.0
MMD2_k127_208204_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 532.0
MMD2_k127_208204_10 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000178 269.0
MMD2_k127_208204_11 translation release factor activity K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002392 269.0
MMD2_k127_208204_12 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001627 256.0
MMD2_k127_208204_13 PFAM Thioredoxin domain K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000002306 243.0
MMD2_k127_208204_14 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000007252 220.0
MMD2_k127_208204_15 Exonuclease K07502 - - 0.000000000000000000000000000000000000000000000000000001153 207.0
MMD2_k127_208204_16 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000008583 207.0
MMD2_k127_208204_17 response to abiotic stimulus - - - 0.0000000000000000000000000000000000000000000005454 182.0
MMD2_k127_208204_18 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000558 183.0
MMD2_k127_208204_19 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000000000000000000000001808 139.0
MMD2_k127_208204_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 415.0
MMD2_k127_208204_20 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000003929 131.0
MMD2_k127_208204_21 - - - - 0.000000000000000000000000000009443 126.0
MMD2_k127_208204_22 Ig-like domain from next to BRCA1 gene - - - 0.0000000000000000000000082 118.0
MMD2_k127_208204_23 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000003135 55.0
MMD2_k127_208204_24 Putative ATP-binding cassette K01992 - - 0.00000007713 60.0
MMD2_k127_208204_3 NUDIX domain K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006082 366.0
MMD2_k127_208204_4 Rad50 zinc hook motif K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000426 373.0
MMD2_k127_208204_5 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 351.0
MMD2_k127_208204_6 Heat shock protein DnaJ domain protein K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 325.0
MMD2_k127_208204_7 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03546,K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 304.0
MMD2_k127_208204_8 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000099 297.0
MMD2_k127_208204_9 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003813 272.0
MMD2_k127_2091636_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 434.0
MMD2_k127_2091636_1 SMART AAA ATPase K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008118 426.0
MMD2_k127_2091636_2 Aminotransferase K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 422.0
MMD2_k127_2091636_3 PFAM thioesterase superfamily protein - - - 0.000000000000000000000000000000000000000000001069 170.0
MMD2_k127_2091636_4 GtrA-like protein - - - 0.00000000000000000000000000000000000000003016 162.0
MMD2_k127_2144642_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 9.082e-280 874.0
MMD2_k127_2144642_1 PFAM glycosyl transferase family 3 K00756 - 2.4.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007034 540.0
MMD2_k127_2144642_2 TIGRFAM RNA polymerase sigma-54 factor, RpoN K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 340.0
MMD2_k127_2181851_0 PFAM Dak phosphatase K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 444.0
MMD2_k127_2181851_1 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000001279 184.0
MMD2_k127_2181851_2 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000001584 164.0
MMD2_k127_2181851_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000002731 64.0
MMD2_k127_2230916_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 363.0
MMD2_k127_2230916_1 CAAX protease self-immunity K07052 - - 0.000000000000000000000000000000000000000000000000000000000000007568 225.0
MMD2_k127_2230916_2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000000000000002288 197.0
MMD2_k127_2230916_3 Protein of unknown function (DUF1295) - - - 0.0000000000000000000000000000000003199 139.0
MMD2_k127_2230916_4 Nucleotidyltransferase domain - - - 0.0000000000000001144 86.0
MMD2_k127_2276585_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 469.0
MMD2_k127_2276585_1 PFAM peptidase S58, DmpA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009751 411.0
MMD2_k127_2276585_10 PFAM AzlC family protein - - - 0.0000000000000000000000000000000000000000000000000000000000003803 226.0
MMD2_k127_2276585_11 TIGRFAM thioredoxin K03671 - - 0.0000000000000000000000000000000000000000000000000000004049 201.0
MMD2_k127_2276585_12 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000013 201.0
MMD2_k127_2276585_13 PFAM DegV family protein - - - 0.00000000000000000000000000000000000000000000004265 180.0
MMD2_k127_2276585_14 TIGRFAM carbohydrate kinase, thermoresistant glucokinase family K00851 - 2.7.1.12 0.000000000000000000000000000000000000000002689 169.0
MMD2_k127_2276585_15 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000004557 171.0
MMD2_k127_2276585_16 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000002012 163.0
MMD2_k127_2276585_17 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.0000000000000000000000000000004004 132.0
MMD2_k127_2276585_18 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000179 114.0
MMD2_k127_2276585_19 2-dehydropantoate 2-reductase activity K00077 - 1.1.1.169 0.0000000000000000001984 91.0
MMD2_k127_2276585_2 PFAM major facilitator superfamily MFS_1 K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 400.0
MMD2_k127_2276585_20 membrane - - - 0.0000000000000000002042 96.0
MMD2_k127_2276585_21 - - - - 0.0000000000000000002335 97.0
MMD2_k127_2276585_3 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 383.0
MMD2_k127_2276585_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 340.0
MMD2_k127_2276585_5 Magnesium transport protein CorA K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 330.0
MMD2_k127_2276585_6 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 316.0
MMD2_k127_2276585_7 PFAM regulatory protein, MerR K22491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 295.0
MMD2_k127_2276585_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001504 283.0
MMD2_k127_2276585_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007687 235.0
MMD2_k127_2286261_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 506.0
MMD2_k127_2286261_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001241 268.0
MMD2_k127_2286261_2 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.0000000000000003099 79.0
MMD2_k127_2394675_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 528.0
MMD2_k127_2394675_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 385.0
MMD2_k127_2394675_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000001338 145.0
MMD2_k127_2394675_3 Phospholipid methyltransferase - - - 0.0000000000000000000000000004466 121.0
MMD2_k127_2405897_0 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005038 335.0
MMD2_k127_2405897_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 298.0
MMD2_k127_2405897_2 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006787 233.0
MMD2_k127_2405897_3 integral membrane protein - - - 0.000000000000000000000000000000000000000000000000000000004576 206.0
MMD2_k127_2405897_4 PFAM Abortive infection protein - - - 0.0000000000000000000000000000000000000000000000004641 181.0
MMD2_k127_2405897_5 Putative ATP-binding cassette K01992 - - 0.00000000000000002351 96.0
MMD2_k127_2415614_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 569.0
MMD2_k127_2415614_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 432.0
MMD2_k127_2415614_10 - - - - 0.0009052 49.0
MMD2_k127_2415614_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 384.0
MMD2_k127_2415614_3 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 348.0
MMD2_k127_2415614_4 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 339.0
MMD2_k127_2415614_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 329.0
MMD2_k127_2415614_6 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.00000000000000000000000000000000000000000000000000000000000002092 223.0
MMD2_k127_2415614_7 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000002503 225.0
MMD2_k127_2415614_9 acetyltransferase K00014 - 1.1.1.25 0.00000000000000003286 91.0
MMD2_k127_2423014_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 392.0
MMD2_k127_2423014_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 299.0
MMD2_k127_2423014_10 - - - - 0.0001189 51.0
MMD2_k127_2423014_11 PFAM GCN5-related N-acetyltransferase - - - 0.0002447 49.0
MMD2_k127_2423014_12 - - - - 0.0008077 46.0
MMD2_k127_2423014_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001732 286.0
MMD2_k127_2423014_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003574 248.0
MMD2_k127_2423014_4 nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003025 225.0
MMD2_k127_2423014_5 Ferritin-like domain K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000001037 219.0
MMD2_k127_2423014_6 PFAM Haloacid dehalogenase domain protein hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000001047 209.0
MMD2_k127_2423014_7 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000007221 142.0
MMD2_k127_2423014_8 PFAM 6-O-methylguanine DNA methyltransferase, DNA binding domain K07443 - - 0.000000000000000000000000001436 115.0
MMD2_k127_2423014_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000001998 55.0
MMD2_k127_2483725_0 PFAM VanW family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 495.0
MMD2_k127_2483725_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002368 329.0
MMD2_k127_2483725_2 methyltransferase K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001991 263.0
MMD2_k127_2483725_3 PFAM phospholipase D Transphosphatidylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001095 264.0
MMD2_k127_2483725_4 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000212 252.0
MMD2_k127_2483725_5 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003317 258.0
MMD2_k127_2483725_6 KR domain K03793 - 1.5.1.33 0.00000000000000000000000000000000000000000000000000000001832 205.0
MMD2_k127_2483725_7 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.000000000000000000000000006288 111.0
MMD2_k127_2502815_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00647,K09458 - 2.3.1.179,2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 506.0
MMD2_k127_2502815_1 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 512.0
MMD2_k127_2502815_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 405.0
MMD2_k127_2502815_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 299.0
MMD2_k127_2502815_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000001084 231.0
MMD2_k127_2502815_5 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000777 185.0
MMD2_k127_2502815_6 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000002569 77.0
MMD2_k127_2528123_0 ATPase associated with various cellular activities, AAA_5 K03696 - - 0.0 1289.0
MMD2_k127_2528123_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.497e-241 759.0
MMD2_k127_2528123_10 PFAM NMT1 THI5 like domain protein K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 318.0
MMD2_k127_2528123_11 PFAM deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 295.0
MMD2_k127_2528123_12 PhoQ Sensor K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 318.0
MMD2_k127_2528123_13 Deoxynucleoside kinase K15518 - 2.7.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003253 281.0
MMD2_k127_2528123_14 ATPases associated with a variety of cellular activities K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002042 282.0
MMD2_k127_2528123_15 PFAM binding-protein-dependent transport systems inner membrane component K02050 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000117 273.0
MMD2_k127_2528123_16 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 - 2.4.2.22 0.000000000000000000000000000000000000000000000000000000000000000000000000003917 256.0
MMD2_k127_2528123_17 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000000000002117 220.0
MMD2_k127_2528123_18 DNA methylase - - - 0.0000000000000000000000000000000000000000000000000000000000002174 224.0
MMD2_k127_2528123_19 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000004823 183.0
MMD2_k127_2528123_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 564.0
MMD2_k127_2528123_20 - - - - 0.000000000000000000000000000000000000000000004296 176.0
MMD2_k127_2528123_21 UTRA K03710 - - 0.00000000000000000000000000000000000000000001481 171.0
MMD2_k127_2528123_22 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000005761 162.0
MMD2_k127_2528123_23 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000006885 169.0
MMD2_k127_2528123_24 FMN binding - - - 0.000000000000000000000000000000000325 137.0
MMD2_k127_2528123_25 - - - - 0.000000000000000000000000000000001879 132.0
MMD2_k127_2528123_26 sterol carrier protein - - - 0.000000000000000000000000000000006697 134.0
MMD2_k127_2528123_27 iron-sulfur cluster assembly - - - 0.00000000000000000000000000002623 118.0
MMD2_k127_2528123_28 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.0000000000000000000000000000283 118.0
MMD2_k127_2528123_29 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000005412 122.0
MMD2_k127_2528123_3 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 522.0
MMD2_k127_2528123_30 DNA polymerase III (delta' subunit) K02340 - 2.7.7.7 0.0000000000000000000000001079 118.0
MMD2_k127_2528123_31 - - - - 0.000000000000000000000006428 108.0
MMD2_k127_2528123_32 Protein of unknown function (DUF3467) - - - 0.0000000000000000297 88.0
MMD2_k127_2528123_35 beta-lactamase domain protein K05555 - - 0.00005876 55.0
MMD2_k127_2528123_4 PFAM Pyridoxal-dependent decarboxylase K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000788 473.0
MMD2_k127_2528123_5 FGGY family of carbohydrate kinase, N-terminal domain protein K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 400.0
MMD2_k127_2528123_6 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 377.0
MMD2_k127_2528123_7 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 328.0
MMD2_k127_2528123_8 L-asparaginase II K01424 - 3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 331.0
MMD2_k127_2528123_9 transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 330.0
MMD2_k127_2533409_0 Alpha-Mannosidase K01191,K15524 GO:0003674,GO:0003824,GO:0004553,GO:0004559,GO:0005975,GO:0005996,GO:0006013,GO:0006464,GO:0006517,GO:0006807,GO:0008150,GO:0008152,GO:0009100,GO:0009987,GO:0015923,GO:0016787,GO:0016798,GO:0019318,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0071704,GO:1901135,GO:1901564 3.2.1.170,3.2.1.24 9.217e-266 850.0
MMD2_k127_2533409_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 357.0
MMD2_k127_2533409_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000002821 223.0
MMD2_k127_2577093_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006323 544.0
MMD2_k127_2577093_1 Formiminotransferase domain, N-terminal subdomain K00603,K13990 - 2.1.2.5,4.3.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 521.0
MMD2_k127_2577093_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 446.0
MMD2_k127_2577093_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000631 344.0
MMD2_k127_2577093_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001223 229.0
MMD2_k127_2577093_5 O-methyltransferase activity K00545 - 2.1.1.6 0.0000000000000000000000000000000000000000000000000005687 194.0
MMD2_k127_2577093_6 Peptidase, M23 K21471 - - 0.000000000000003359 87.0
MMD2_k127_2577093_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000002077 52.0
MMD2_k127_2595023_0 associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009887 385.0
MMD2_k127_2595023_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.00000000000000000000000000000000000000000000000000000000000000007424 231.0
MMD2_k127_2595023_2 NurA - - - 0.000000000000000000000000000000000000009622 160.0
MMD2_k127_2646785_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1149.0
MMD2_k127_2646785_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 477.0
MMD2_k127_2646785_10 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006306 307.0
MMD2_k127_2646785_11 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206,K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000005192 253.0
MMD2_k127_2646785_12 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000006813 227.0
MMD2_k127_2646785_13 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000009949 197.0
MMD2_k127_2646785_14 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000001952 204.0
MMD2_k127_2646785_15 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000005908 199.0
MMD2_k127_2646785_16 - - - - 0.000000000000000000000000000000000000000000001344 182.0
MMD2_k127_2646785_17 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.000000000000000000000000000000000002123 150.0
MMD2_k127_2646785_18 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000718 123.0
MMD2_k127_2646785_19 Pyridoxamine 5'-phosphate oxidase K09979 - - 0.00000000000000000001548 102.0
MMD2_k127_2646785_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006104 447.0
MMD2_k127_2646785_3 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 360.0
MMD2_k127_2646785_4 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009423 332.0
MMD2_k127_2646785_5 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 327.0
MMD2_k127_2646785_6 peptidase M42 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 319.0
MMD2_k127_2646785_7 TIGRFAM LAO AO transport system ATPase K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 314.0
MMD2_k127_2646785_8 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 305.0
MMD2_k127_2646785_9 PFAM secretion protein HlyD family protein K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005969 310.0
MMD2_k127_2675433_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 5.522e-277 880.0
MMD2_k127_2675433_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.306e-244 769.0
MMD2_k127_2675433_10 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000009328 188.0
MMD2_k127_2675433_11 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000369 198.0
MMD2_k127_2675433_12 Amino acid permease - - - 0.00000000000000000008687 104.0
MMD2_k127_2675433_13 Protein of unknown function (DUF1706) - - - 0.00000000000008377 78.0
MMD2_k127_2675433_14 - - - - 0.000000009261 61.0
MMD2_k127_2675433_15 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.0000001912 61.0
MMD2_k127_2675433_2 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 500.0
MMD2_k127_2675433_3 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 434.0
MMD2_k127_2675433_4 TIGRFAM DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 351.0
MMD2_k127_2675433_5 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002968 336.0
MMD2_k127_2675433_6 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 290.0
MMD2_k127_2675433_7 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001471 283.0
MMD2_k127_2675433_8 Putative NAD(P)-binding K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004282 252.0
MMD2_k127_2675433_9 TrkA-N domain K03499,K10716 - - 0.0000000000000000000000000000000000000000000000000001339 196.0
MMD2_k127_2802767_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.717e-230 744.0
MMD2_k127_2802767_1 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 426.0
MMD2_k127_2818116_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K09181 - - 0.0 1242.0
MMD2_k127_2818116_1 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007712 283.0
MMD2_k127_2818116_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000006783 239.0
MMD2_k127_2818116_3 L,D-transpeptidase catalytic domain - - - 0.000000000001386 81.0
MMD2_k127_285063_0 PFAM ABC transporter transmembrane region K06147 - - 1.263e-249 788.0
MMD2_k127_285063_1 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000005594 174.0
MMD2_k127_285063_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000388 157.0
MMD2_k127_285063_3 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000001681 131.0
MMD2_k127_285063_4 metal-dependent membrane protease K07052 - - 0.00004314 50.0
MMD2_k127_2869811_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004625 394.0
MMD2_k127_2869811_1 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 371.0
MMD2_k127_2869811_2 lipid binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004927 305.0
MMD2_k127_2869811_3 LysM domain - - - 0.00000000000000000000000000000000000000000000000000000001127 218.0
MMD2_k127_2869811_4 - - - - 0.000000000000000000000009754 117.0
MMD2_k127_2869811_5 Yip1 domain - - - 0.00000000000000005641 86.0
MMD2_k127_2869811_6 peptidyl-tyrosine sulfation - - - 0.0000000000005376 74.0
MMD2_k127_2921583_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 1.919e-203 657.0
MMD2_k127_2921583_1 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006139 499.0
MMD2_k127_2921583_10 ABC transporter substrate-binding protein K15580 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 321.0
MMD2_k127_2921583_11 Binding-protein-dependent transport system inner membrane component K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 295.0
MMD2_k127_2921583_12 Permease K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001154 280.0
MMD2_k127_2921583_13 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007856 266.0
MMD2_k127_2921583_14 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000004459 208.0
MMD2_k127_2921583_15 PFAM Maf family protein K06287 - - 0.0000000000000000000000000000000000000000000000008548 185.0
MMD2_k127_2921583_16 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.00000000000000000000000000000000000000002725 155.0
MMD2_k127_2921583_17 CAAX protease self-immunity K07052 - - 0.00000000000000000000000001016 121.0
MMD2_k127_2921583_18 'Cold-shock' DNA-binding domain K03704 - - 0.000000000000000000000006339 106.0
MMD2_k127_2921583_19 Metalloenzyme superfamily - - - 0.0000000000000002858 93.0
MMD2_k127_2921583_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 506.0
MMD2_k127_2921583_20 Prenyltransferase and squalene oxidase repeat - - - 0.0000000000002998 83.0
MMD2_k127_2921583_21 Prenyltransferase and squalene oxidase repeat - - - 0.000000000003716 79.0
MMD2_k127_2921583_22 cytochrome K08738 - - 0.00007255 53.0
MMD2_k127_2921583_3 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 507.0
MMD2_k127_2921583_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 486.0
MMD2_k127_2921583_5 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004119 489.0
MMD2_k127_2921583_6 Belongs to the ABC transporter superfamily K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 465.0
MMD2_k127_2921583_7 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 456.0
MMD2_k127_2921583_8 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002164 344.0
MMD2_k127_2921583_9 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004951 338.0
MMD2_k127_2946347_0 PFAM cytochrome c biogenesis protein, transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001343 284.0
MMD2_k127_2946347_1 Predicted membrane protein (DUF2085) - - - 0.0000000000000000000000000000000000000000000000000000000000003073 222.0
MMD2_k127_2946347_2 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000002029 154.0
MMD2_k127_2946347_3 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.00000000000000000000000000008652 126.0
MMD2_k127_3054432_0 MFS/sugar transport protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007143 284.0
MMD2_k127_3054432_1 PFAM Diacylglycerol kinase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000008825 236.0
MMD2_k127_3054432_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000002519 146.0
MMD2_k127_3054432_3 Periplasmic component of the Tol biopolymer transport system - - - 0.0000000000008858 80.0
MMD2_k127_3054432_4 isoprenylcysteine carboxyl methyltransferase - - - 0.00000000001263 73.0
MMD2_k127_3144376_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 509.0
MMD2_k127_3144376_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 439.0
MMD2_k127_3144376_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 372.0
MMD2_k127_3144376_3 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 321.0
MMD2_k127_3144376_4 ATPases associated with a variety of cellular activities K01990 - - 0.00000000000000000004538 95.0
MMD2_k127_316254_0 Heat shock 70 kDa protein K04043 - - 6.822e-296 919.0
MMD2_k127_316254_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 374.0
MMD2_k127_316254_10 Ribosomal protein S21 K02970 - - 0.000000000000000000512 90.0
MMD2_k127_316254_11 regulation of response to stimulus K01126,K21449 - 3.1.4.46 0.00000000000001047 86.0
MMD2_k127_316254_12 YGGT family K02221 - - 0.00000000000005173 75.0
MMD2_k127_316254_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 340.0
MMD2_k127_316254_3 major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 296.0
MMD2_k127_316254_4 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000055 288.0
MMD2_k127_316254_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004097 275.0
MMD2_k127_316254_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000003815 221.0
MMD2_k127_316254_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000007399 137.0
MMD2_k127_316254_8 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000004812 121.0
MMD2_k127_316254_9 Belongs to the UPF0235 family K09131 - - 0.000000000000000000009749 98.0
MMD2_k127_3187203_0 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001126 289.0
MMD2_k127_3187203_1 Glycosyl transferases group 1 K21001 - - 0.000000000000000000000000000000000000000000000000000000001287 217.0
MMD2_k127_3187203_2 Polysaccharide biosynthesis protein K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000003172 96.0
MMD2_k127_3212466_0 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 340.0
MMD2_k127_3212466_1 MFS/sugar transport protein K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 300.0
MMD2_k127_3212466_2 GxGYxYP putative glycoside hydrolase C-terminal domain - - - 0.00000000000000000000000000000001006 146.0
MMD2_k127_3212466_3 TIGRFAM geranylgeranyl reductase K17830 - 1.3.1.101,1.3.7.11 0.0000000000000000000008345 110.0
MMD2_k127_3213507_0 PFAM magnesium chelatase ChlI subunit K07391 - - 9.749e-223 701.0
MMD2_k127_3213507_1 Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 391.0
MMD2_k127_3213507_2 Nitrite reductase K00368 - 1.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 329.0
MMD2_k127_3213507_3 MFS/sugar transport protein K03292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004379 262.0
MMD2_k127_3213507_4 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.000000000000000000000000000000000000000000000000005776 189.0
MMD2_k127_3213507_5 nitrite reductase, copper-containing K00368 - 1.7.2.1 0.0000000000000000000000000000000000001152 143.0
MMD2_k127_3217802_0 2-hydroxy-3-oxopropionate reductase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 355.0
MMD2_k127_3217802_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.00000000000000000000000000000000000000000000006011 174.0
MMD2_k127_3217802_2 helix_turn_helix, Lux Regulon K07684 - - 0.0000000000002766 79.0
MMD2_k127_3217802_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.00000002314 57.0
MMD2_k127_3217802_4 tail specific protease K03797 - 3.4.21.102 0.0003245 49.0
MMD2_k127_3294463_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 436.0
MMD2_k127_3294463_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 382.0
MMD2_k127_3294463_2 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 321.0
MMD2_k127_3294463_3 ATPases associated with a variety of cellular activities K02028,K02029,K10004,K10010,K10038 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 314.0
MMD2_k127_3294463_4 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001833 252.0
MMD2_k127_3294463_5 Belongs to the bacterial solute-binding protein 3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004423 247.0
MMD2_k127_3294463_6 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000009476 234.0
MMD2_k127_3294463_7 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000309 143.0
MMD2_k127_3294463_9 - - - - 0.00000000000000000000000000000276 127.0
MMD2_k127_329791_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 4.867e-216 694.0
MMD2_k127_329791_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000001535 215.0
MMD2_k127_329791_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000009319 177.0
MMD2_k127_3323932_0 DEAD DEAH box helicase domain protein K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 601.0
MMD2_k127_3323932_1 Two component transcriptional regulator, winged helix family K07669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008176 326.0
MMD2_k127_3323932_2 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000000000000000000000494 203.0
MMD2_k127_3323932_3 LysM domain - - - 0.00000000000000000000000000000000000001484 154.0
MMD2_k127_3323932_4 Putative zincin peptidase - - - 0.0000000000398 72.0
MMD2_k127_3327309_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.101e-262 835.0
MMD2_k127_3327309_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.167e-223 722.0
MMD2_k127_3327309_2 SIS domain K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 378.0
MMD2_k127_3327309_3 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 359.0
MMD2_k127_3327309_4 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 330.0
MMD2_k127_3327309_5 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 319.0
MMD2_k127_3327309_6 Belongs to the HAD-like hydrolase superfamily K01101 - 3.1.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000005045 271.0
MMD2_k127_3327309_7 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000001423 223.0
MMD2_k127_3327309_8 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000002331 145.0
MMD2_k127_3368336_0 Glycyl-tRNA synthetase alpha subunit K14164 - 6.1.1.14 0.0 1111.0
MMD2_k127_3368336_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 606.0
MMD2_k127_3368336_10 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000000000000000000000167 187.0
MMD2_k127_3368336_11 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000002132 137.0
MMD2_k127_3368336_12 Alpha beta hydrolase - - - 0.00000000000000000000004701 103.0
MMD2_k127_3368336_2 Pyridine nucleotide-disulphide oxidoreductase dimerisation region K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005695 452.0
MMD2_k127_3368336_3 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 445.0
MMD2_k127_3368336_4 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007846 406.0
MMD2_k127_3368336_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 376.0
MMD2_k127_3368336_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 310.0
MMD2_k127_3368336_7 PFAM YbbR family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002281 273.0
MMD2_k127_3368336_8 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000006431 253.0
MMD2_k127_3368336_9 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000004676 239.0
MMD2_k127_3412772_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 463.0
MMD2_k127_3412772_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004154 458.0
MMD2_k127_3412772_10 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000003707 123.0
MMD2_k127_3412772_11 PFAM amine oxidase - - - 0.00000000000000002297 83.0
MMD2_k127_3412772_12 - - - - 0.0000000000000002463 87.0
MMD2_k127_3412772_2 Coenzyme A transferase K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 391.0
MMD2_k127_3412772_3 PFAM amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 397.0
MMD2_k127_3412772_4 CorA-like Mg2+ transporter protein K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 364.0
MMD2_k127_3412772_5 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 308.0
MMD2_k127_3412772_6 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 317.0
MMD2_k127_3412772_7 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006161 290.0
MMD2_k127_3412772_8 - - - - 0.00000000000000000000000000000000000000000000000004022 191.0
MMD2_k127_3412772_9 peptidase - - - 0.000000000000000000000000000000000007382 147.0
MMD2_k127_3430526_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 568.0
MMD2_k127_3430526_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 481.0
MMD2_k127_3430526_2 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 381.0
MMD2_k127_3430526_3 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 286.0
MMD2_k127_3430526_4 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000213 218.0
MMD2_k127_3430526_5 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000005533 64.0
MMD2_k127_3454915_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 467.0
MMD2_k127_3454915_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 320.0
MMD2_k127_3454915_2 Molydopterin dinucleotide binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001777 282.0
MMD2_k127_3454915_3 Dihydroxyacetone kinase family - - - 0.00000000000000000000000000000000000000000000002533 181.0
MMD2_k127_3454915_4 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000003145 129.0
MMD2_k127_3454915_5 Protein of unknown function (DUF3341) - - - 0.0000000000000000001633 100.0
MMD2_k127_3454915_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000973 98.0
MMD2_k127_3454915_7 Cytochrome c - - - 0.000000001372 65.0
MMD2_k127_3454915_8 COG1977 Molybdopterin converting factor, small subunit K03636 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 - 0.00003019 51.0
MMD2_k127_3484426_0 pathogenesis K21471,K21687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 381.0
MMD2_k127_3484426_1 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000009997 262.0
MMD2_k127_348558_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000009683 251.0
MMD2_k127_348558_1 response regulator receiver K07668,K07775 - - 0.00000000000000000000000000000000000000000000000000000000000000000002929 241.0
MMD2_k127_348558_2 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000002988 222.0
MMD2_k127_348558_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000002229 153.0
MMD2_k127_3663315_0 ATP synthesis coupled electron transport K00336 GO:0003674,GO:0003824,GO:0003954,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0009405,GO:0010941,GO:0016020,GO:0016491,GO:0016651,GO:0030312,GO:0033668,GO:0035821,GO:0042981,GO:0043067,GO:0043069,GO:0044003,GO:0044068,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0048037,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051536,GO:0051540,GO:0051701,GO:0051704,GO:0051817,GO:0052040,GO:0052041,GO:0052150,GO:0052248,GO:0052433,GO:0052490,GO:0055114,GO:0060548,GO:0065007,GO:0071944 1.6.5.3 2.601e-208 656.0
MMD2_k127_3663315_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 611.0
MMD2_k127_3663315_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 587.0
MMD2_k127_3663315_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000001915 184.0
MMD2_k127_3663315_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000004736 181.0
MMD2_k127_3678060_0 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K12528 - - 0.0 1371.0
MMD2_k127_3678060_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1032.0
MMD2_k127_3678060_10 Thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000009504 161.0
MMD2_k127_3678060_11 Guanylyl transferase CofC like K14941 - 2.7.7.68 0.0000000000000000000000009676 113.0
MMD2_k127_3678060_12 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000002575 71.0
MMD2_k127_3678060_13 Nitroreductase family - - - 0.00000002394 56.0
MMD2_k127_3678060_2 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 577.0
MMD2_k127_3678060_3 CO dehydrogenase flavoprotein C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 499.0
MMD2_k127_3678060_4 Uncharacterised protein family UPF0052 K11212 - 2.7.8.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 325.0
MMD2_k127_3678060_5 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003398 321.0
MMD2_k127_3678060_6 WD-40 repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 326.0
MMD2_k127_3678060_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000905 237.0
MMD2_k127_3678060_8 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000001425 242.0
MMD2_k127_3678060_9 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000003381 226.0
MMD2_k127_3716135_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000009286 162.0
MMD2_k127_3716135_2 Glycosyltransferase - - - 0.00003487 52.0
MMD2_k127_3764535_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 384.0
MMD2_k127_3764535_1 ABC transporter related K01990,K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001329 266.0
MMD2_k127_3764535_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000003168 239.0
MMD2_k127_3764535_3 Transport permease protein K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000008801 199.0
MMD2_k127_3829142_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01840 - 5.4.2.8 6.281e-209 663.0
MMD2_k127_3829142_1 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 517.0
MMD2_k127_3829142_10 gas vesicle protein - - - 0.00000001981 60.0
MMD2_k127_3829142_11 Bacterial SH3 domain - - - 0.000003001 59.0
MMD2_k127_3829142_2 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 406.0
MMD2_k127_3829142_3 Belongs to the FPP GGPP synthase family K00805,K02523 - 2.5.1.30,2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003508 285.0
MMD2_k127_3829142_4 PFAM glycosyl transferase, family 28 K05841 - 2.4.1.173 0.000000000000000000000000000000000000000000000000000000000000000000000000000002655 277.0
MMD2_k127_3829142_5 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000177 227.0
MMD2_k127_3829142_6 Haloacid dehalogenase domain protein hydrolase - - - 0.000000000000000000000000000000000000000000002064 169.0
MMD2_k127_3829142_7 Histidine kinase-like ATPase domain - - - 0.000000000000001676 82.0
MMD2_k127_3829142_8 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000001201 68.0
MMD2_k127_3829142_9 - - - - 0.0000000001601 67.0
MMD2_k127_3849514_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 324.0
MMD2_k127_3849514_1 Acetyltransferase (GNAT) domain K03823 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.183 0.0000000000000000000000000000000000000000000000000000000000004123 220.0
MMD2_k127_3849514_2 - - - - 0.00000000000000000000000000000000006019 139.0
MMD2_k127_3849514_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000003384 139.0
MMD2_k127_3849514_4 - - - - 0.00000000000000000000000000001039 124.0
MMD2_k127_3899091_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.703e-230 721.0
MMD2_k127_3899091_1 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009567 466.0
MMD2_k127_3899091_2 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 419.0
MMD2_k127_3899091_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002043 285.0
MMD2_k127_3899091_4 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003082 251.0
MMD2_k127_3899091_5 Methyltransferase domain - - - 0.0000000000000000001233 103.0
MMD2_k127_3899091_6 lysyltransferase activity K07027 - - 0.0000000000004604 81.0
MMD2_k127_3929464_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 317.0
MMD2_k127_3929464_1 Transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000159 230.0
MMD2_k127_3929464_2 TIGRFAM glutaredoxin-like domain protein - - - 0.00000000000000000000000000000000000000000000001296 188.0
MMD2_k127_3929464_3 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000000000000000000005453 111.0
MMD2_k127_3929464_4 lysyltransferase activity K07027 - - 0.0006215 44.0
MMD2_k127_3930936_0 PFAM type II secretion system protein E K02283 - - 1.806e-207 653.0
MMD2_k127_3930936_1 PFAM response regulator receiver K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 355.0
MMD2_k127_3930936_2 PFAM type II secretion system protein K12511 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 336.0
MMD2_k127_3930936_3 PFAM type II secretion system protein K12510 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002917 275.0
MMD2_k127_3930936_4 histidine kinase, dimerisation and phosphoacceptor region K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000001631 260.0
MMD2_k127_3930936_5 ATP hydrolysis coupled proton transport - - - 0.00000000000000000000000000000000000000000000006778 177.0
MMD2_k127_3930936_6 competence protein - - - 0.0000000000000000000000000000000000000000000001075 181.0
MMD2_k127_3930936_7 Flp pilus assembly protein CpaB K02279 - - 0.00000000000000000000000000000000000000008564 164.0
MMD2_k127_3936691_0 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 434.0
MMD2_k127_3936691_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000004346 228.0
MMD2_k127_3936691_2 Glycosyl transferase 4-like domain - - - 0.00000000000009709 83.0
MMD2_k127_3936691_3 Glycosyl transferase - - - 0.000000000002692 75.0
MMD2_k127_4013689_0 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 586.0
MMD2_k127_4013689_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 357.0
MMD2_k127_4013689_2 Belongs to the glycosyl hydrolase 1 family K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004434 299.0
MMD2_k127_4013689_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000183 162.0
MMD2_k127_4013689_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000000000000000000000000000004427 155.0
MMD2_k127_4013689_5 Zincin-like metallopeptidase K00930 - 2.7.2.8 0.0000000000000003635 84.0
MMD2_k127_4024084_0 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 349.0
MMD2_k127_4024084_1 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 315.0
MMD2_k127_4024084_10 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00006674 53.0
MMD2_k127_4024084_2 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001482 284.0
MMD2_k127_4024084_3 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009003 276.0
MMD2_k127_4024084_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000001832 237.0
MMD2_k127_4024084_5 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000004908 170.0
MMD2_k127_4024084_6 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000004927 168.0
MMD2_k127_4024084_7 Asp23 family, cell envelope-related function - - - 0.0000000000000000000000000007803 119.0
MMD2_k127_4024084_8 Specifically methylates the guanine in position - - - 0.00000000000000001991 93.0
MMD2_k127_4024084_9 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000002255 84.0
MMD2_k127_4029620_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.561e-264 824.0
MMD2_k127_4029620_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000001513 64.0
MMD2_k127_4041835_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 2.521e-256 804.0
MMD2_k127_4041835_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006226 617.0
MMD2_k127_4041835_2 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001695 272.0
MMD2_k127_4041835_3 histidine kinase A domain protein K02482 - 2.7.13.3 0.0000000002933 72.0
MMD2_k127_4041835_4 Belongs to the SOS response-associated peptidase family - - - 0.00000000689 61.0
MMD2_k127_4047506_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 453.0
MMD2_k127_4047506_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 370.0
MMD2_k127_4047506_2 PFAM Alpha beta hydrolase fold-3 domain protein K14731 - 3.1.1.83 0.00000000000000000000000000000000000000000000000000000000000000000009409 241.0
MMD2_k127_4047506_3 signal peptide peptidase SppA, 36K type K04773 - - 0.000000000000000000000000000000000000000000000000000000000005013 221.0
MMD2_k127_4047506_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0055114,GO:0098796,GO:1902494 1.6.5.3 0.000000000000000000000000000000000000000002244 160.0
MMD2_k127_4071070_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0008479,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046116,GO:0046483,GO:0046872,GO:0046914,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 429.0
MMD2_k127_4071070_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001394 286.0
MMD2_k127_4071070_2 COGs COG0491 Zn-dependent hydrolase including glyoxylase - - - 0.00000000000000000000000000000000000000000000000003588 184.0
MMD2_k127_4071070_3 PFAM Citrate transporter - - - 0.00000000000000001248 83.0
MMD2_k127_4071070_4 PBP superfamily domain K02040 - - 0.000000003613 69.0
MMD2_k127_4073539_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 426.0
MMD2_k127_4073539_1 Belongs to the ABC transporter superfamily K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 393.0
MMD2_k127_4073539_10 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000005252 142.0
MMD2_k127_4073539_11 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000001019 98.0
MMD2_k127_4073539_12 Psort location CytoplasmicMembrane, score 9.49 - - - 0.0000001389 53.0
MMD2_k127_4073539_13 Histone deacetylase domain - - - 0.0003663 51.0
MMD2_k127_4073539_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 359.0
MMD2_k127_4073539_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006181 360.0
MMD2_k127_4073539_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 315.0
MMD2_k127_4073539_5 DNA recombination K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007591 273.0
MMD2_k127_4073539_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000226 243.0
MMD2_k127_4073539_7 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000005506 241.0
MMD2_k127_4073539_8 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000001077 193.0
MMD2_k127_4073539_9 spore germination - - - 0.00000000000000000000000000000000000005608 156.0
MMD2_k127_4073787_0 ABC transporter K17215 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 499.0
MMD2_k127_4073787_1 transporter K03292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002683 453.0
MMD2_k127_4073787_10 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000001265 222.0
MMD2_k127_4073787_11 Periplasmic binding protein domain K10439 - - 0.000000000000000000000000000000000000000000000000000000001773 214.0
MMD2_k127_4073787_12 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.0000000000000000000000000000000000000000000000000000003788 203.0
MMD2_k127_4073787_13 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000009142 197.0
MMD2_k127_4073787_14 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000001378 201.0
MMD2_k127_4073787_15 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000022 190.0
MMD2_k127_4073787_16 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs K00087,K03519 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000002543 181.0
MMD2_k127_4073787_17 FCD - - - 0.000000000000000000000000000000000000000000003097 173.0
MMD2_k127_4073787_18 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000004509 158.0
MMD2_k127_4073787_19 Methyltransferase domain - - - 0.00000000000000000000000000000000002833 144.0
MMD2_k127_4073787_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 369.0
MMD2_k127_4073787_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 353.0
MMD2_k127_4073787_4 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 336.0
MMD2_k127_4073787_5 Beta-lactamase superfamily domain K03476 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008673 309.0
MMD2_k127_4073787_6 Aldehyde oxidase and xanthine dehydrogenase a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003832 279.0
MMD2_k127_4073787_7 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000195 238.0
MMD2_k127_4073787_8 Branched-chain amino acid transport system / permease component K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000002144 238.0
MMD2_k127_4073787_9 PFAM Short-chain dehydrogenase reductase SDR K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000001091 231.0
MMD2_k127_4101665_0 Belongs to the formate--tetrahydrofolate ligase family K00288,K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.5.1.5,3.5.4.9,6.3.4.3 3.412e-312 967.0
MMD2_k127_4101665_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 3.924e-235 748.0
MMD2_k127_4101665_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003573 376.0
MMD2_k127_4101665_11 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 343.0
MMD2_k127_4101665_12 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000978 327.0
MMD2_k127_4101665_13 Uncharacterised ACR (DUF711) K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 325.0
MMD2_k127_4101665_14 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008177 281.0
MMD2_k127_4101665_15 PFAM 60 kDa inner membrane insertion protein K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001875 261.0
MMD2_k127_4101665_16 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000198 254.0
MMD2_k127_4101665_17 heme binding K21472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003321 250.0
MMD2_k127_4101665_18 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008411 248.0
MMD2_k127_4101665_19 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000006065 218.0
MMD2_k127_4101665_2 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 3.196e-207 653.0
MMD2_k127_4101665_20 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.000000000000000000000000000000000000000000000000000000001325 209.0
MMD2_k127_4101665_21 redox protein regulator of disulfide bond formation K04063 - - 0.000000000000000000000000000000000000000000000007143 175.0
MMD2_k127_4101665_22 Integral membrane protein DUF92 - - - 0.000000000000000000000000000000000000000000000683 178.0
MMD2_k127_4101665_23 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000119 167.0
MMD2_k127_4101665_24 Peptidase M50 - - - 0.000000000000000000000000000000000000000000004492 179.0
MMD2_k127_4101665_25 PFAM single-stranded nucleic acid binding R3H domain protein K06346 - - 0.000000000000000000000000000000000000000001416 165.0
MMD2_k127_4101665_26 Deacetylates O-acetyl-ADP ribose. Down-regulates ribonuclease 3 (RNase III) activity. Acts by interacting directly with the region of the ribonuclease that is required for dimerization activation - GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005515,GO:0008150,GO:0008428,GO:0009892,GO:0010605,GO:0016787,GO:0019213,GO:0019219,GO:0019222,GO:0019899,GO:0030234,GO:0031323,GO:0031324,GO:0032069,GO:0032074,GO:0043086,GO:0043900,GO:0044092,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051336,GO:0051346,GO:0060255,GO:0060698,GO:0060699,GO:0060700,GO:0060701,GO:0060702,GO:0061463,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:1900190,GO:1900231 - 0.00000000000000000000000000000000000000003557 168.0
MMD2_k127_4101665_27 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000000001355 159.0
MMD2_k127_4101665_28 Belongs to the MenA family. Type 1 subfamily - - - 0.000000000000000000000000000000000134 138.0
MMD2_k127_4101665_29 succinate dehydrogenase, cytochrome K00241 - - 0.0000000000000000000000000000000004539 141.0
MMD2_k127_4101665_3 Beta-eliminating lyase K01668 - 4.1.99.2 1.365e-203 653.0
MMD2_k127_4101665_30 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000000004938 132.0
MMD2_k127_4101665_31 PQQ-like domain - - - 0.0000000000000000000000000000003223 138.0
MMD2_k127_4101665_32 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000000007812 123.0
MMD2_k127_4101665_33 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.000000000000000000000000000002953 125.0
MMD2_k127_4101665_34 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000006493 132.0
MMD2_k127_4101665_35 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000006668 122.0
MMD2_k127_4101665_36 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000001419 113.0
MMD2_k127_4101665_37 Protein of unknown function (DUF952) - - - 0.0000000000000000000000004738 110.0
MMD2_k127_4101665_38 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000001149 102.0
MMD2_k127_4101665_39 GIY-YIG catalytic domain K07461 - - 0.000000000000000000003403 96.0
MMD2_k127_4101665_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 593.0
MMD2_k127_4101665_40 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000003529 68.0
MMD2_k127_4101665_41 Bacterial PH domain - - - 0.0000001266 63.0
MMD2_k127_4101665_42 Putative esterase - - - 0.0001057 53.0
MMD2_k127_4101665_5 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 549.0
MMD2_k127_4101665_6 Polysaccharide biosynthesis protein K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 518.0
MMD2_k127_4101665_7 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 507.0
MMD2_k127_4101665_8 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 494.0
MMD2_k127_4101665_9 PFAM Cys Met metabolism K01739 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003962,GO:0004123,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009070,GO:0009086,GO:0009092,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0017144,GO:0019279,GO:0019343,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071265,GO:0071266,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 475.0
MMD2_k127_4110728_0 PFAM fumarate lyase K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 461.0
MMD2_k127_4110728_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 308.0
MMD2_k127_4110728_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000002526 234.0
MMD2_k127_4110728_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001175 213.0
MMD2_k127_4110728_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000001189 214.0
MMD2_k127_4110728_5 PFAM RNA binding S1 domain protein - - - 0.0000000000000000000000000000000000000000000008992 176.0
MMD2_k127_4110728_6 phosphate transport regulator (Distant homolog of PhoU) K07220 - - 0.000000000000000000000000000000000000000000001194 172.0
MMD2_k127_4110728_7 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.0000000000000000000000000000000000000000131 155.0
MMD2_k127_4110728_8 Tyrosine recombinase xerD K04763 - - 0.000000000000004922 87.0
MMD2_k127_4110728_9 EamA-like transporter family K11939 - - 0.0000002478 62.0
MMD2_k127_4115666_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 6.437e-222 706.0
MMD2_k127_4115666_1 CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 390.0
MMD2_k127_4115666_2 Domain of unknown function - - - 0.0000000000000000000000000000000000000000000002145 177.0
MMD2_k127_4122310_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 3.001e-238 751.0
MMD2_k127_4122310_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 315.0
MMD2_k127_4122310_10 DinB superfamily - - - 0.0001659 51.0
MMD2_k127_4122310_2 RNA cap guanine-N2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 298.0
MMD2_k127_4122310_3 Phosphoribosyl transferase domain K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000008372 232.0
MMD2_k127_4122310_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000000000000002786 174.0
MMD2_k127_4122310_5 Carbamoyl-phosphate synthetase large chain domain protein K01961,K01968,K11263 - 6.3.4.14,6.4.1.2,6.4.1.3,6.4.1.4 0.00000000000000000000000000000000000000000000033 172.0
MMD2_k127_4122310_6 CYTH domain K05873 - 4.6.1.1 0.0000000000000000000000000000000000000001944 157.0
MMD2_k127_4122310_7 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.000000000000000000000000000002953 125.0
MMD2_k127_4122310_8 AI-2E family transporter - - - 0.000000000000000000000573 101.0
MMD2_k127_4147383_0 AAA domain K02282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 297.0
MMD2_k127_4147383_1 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.000000000000000000000000000000000000000000000000000000000000000001413 237.0
MMD2_k127_4147383_2 PAS domain - - - 0.0000000000000000000000000000000000000000006538 174.0
MMD2_k127_4153797_0 Trimethylamine methyltransferase K14083 - 2.1.1.250 6.586e-195 630.0
MMD2_k127_4153797_1 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
MMD2_k127_4153797_2 transcriptional K03710 - - 0.000000000000000000000000000000000000001305 158.0
MMD2_k127_4188448_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 1.043e-285 900.0
MMD2_k127_4188448_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 501.0
MMD2_k127_4188448_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002641 475.0
MMD2_k127_4188448_3 VIT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 311.0
MMD2_k127_4188448_4 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000001067 205.0
MMD2_k127_4188448_5 DNA methylase K00571,K13581 - 2.1.1.72 0.000000000000000000000000000000000000000000000000002504 184.0
MMD2_k127_4188448_6 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000000004859 186.0
MMD2_k127_4188448_7 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000003327 138.0
MMD2_k127_4216297_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 302.0
MMD2_k127_4216297_1 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001108 270.0
MMD2_k127_4216297_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003274 248.0
MMD2_k127_4216297_3 Glycosyl transferase, family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000002296 240.0
MMD2_k127_4216297_4 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000001313 157.0
MMD2_k127_4228777_0 Belongs to the UbiD family K03182 - 4.1.1.98 5.379e-207 663.0
MMD2_k127_4228777_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 513.0
MMD2_k127_4228777_10 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000006679 204.0
MMD2_k127_4228777_2 SMART Nucleotide binding protein, PINc - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 410.0
MMD2_k127_4228777_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 324.0
MMD2_k127_4228777_4 ATPases associated with a variety of cellular activities K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 312.0
MMD2_k127_4228777_5 PFAM UbiA prenyltransferase K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004299 280.0
MMD2_k127_4228777_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002064 262.0
MMD2_k127_4228777_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000005394 243.0
MMD2_k127_4228777_8 thiamine-containing compound biosynthetic process K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000007422 243.0
MMD2_k127_4228777_9 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000163 221.0
MMD2_k127_4248542_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 3.908e-236 754.0
MMD2_k127_4248542_1 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 380.0
MMD2_k127_4248542_2 short-chain dehydrogenase reductase SDR K12454 - 5.1.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 301.0
MMD2_k127_4248542_3 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000000000000000000007433 171.0
MMD2_k127_4248542_4 PFAM peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000000009012 153.0
MMD2_k127_4248542_5 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0000000000000000000000000000000000003512 146.0
MMD2_k127_4248542_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000002411 147.0
MMD2_k127_4248542_7 PFAM membrane protein of K08972 - - 0.000000000000000000000000000000009115 130.0
MMD2_k127_4267133_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 - 1.2.7.1 0.0 1008.0
MMD2_k127_4267133_1 Acetyltransferase (GNAT) domain - - - 0.000007489 54.0
MMD2_k127_4273922_0 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 296.0
MMD2_k127_4273922_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001747 259.0
MMD2_k127_4273922_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000217 190.0
MMD2_k127_4273922_3 pfkB family carbohydrate kinase - - - 0.00000000000000000000000007349 117.0
MMD2_k127_4297804_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.092e-211 663.0
MMD2_k127_4297804_1 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 344.0
MMD2_k127_4297804_10 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 299.0
MMD2_k127_4297804_11 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004759 272.0
MMD2_k127_4297804_12 glycosyl transferase group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000003563 273.0
MMD2_k127_4297804_13 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000004137 215.0
MMD2_k127_4297804_14 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000009747 223.0
MMD2_k127_4297804_15 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000002177 176.0
MMD2_k127_4297804_16 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000007638 173.0
MMD2_k127_4297804_17 PFAM 6-pyruvoyl tetrahydropterin synthase and K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000004986 153.0
MMD2_k127_4297804_18 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000001035 140.0
MMD2_k127_4297804_19 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000732 114.0
MMD2_k127_4297804_2 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 332.0
MMD2_k127_4297804_20 Belongs to the 'phage' integrase family - - - 0.0002915 49.0
MMD2_k127_4297804_3 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 336.0
MMD2_k127_4297804_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 330.0
MMD2_k127_4297804_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 318.0
MMD2_k127_4297804_6 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 335.0
MMD2_k127_4297804_7 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 308.0
MMD2_k127_4297804_8 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006362 313.0
MMD2_k127_4297804_9 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 310.0
MMD2_k127_43524_0 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006106 399.0
MMD2_k127_43524_1 PFAM RNA binding S1 domain protein K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 367.0
MMD2_k127_43524_2 PFAM sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000000001228 204.0
MMD2_k127_43524_3 membrane - - - 0.000000000000000000000000000000000000000000000000000001775 203.0
MMD2_k127_43524_4 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000002518 170.0
MMD2_k127_43524_6 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000001046 171.0
MMD2_k127_436771_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 1.152e-198 632.0
MMD2_k127_436771_1 response to antibiotic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 573.0
MMD2_k127_436771_10 Methyltransferase - - - 0.0000000000003578 79.0
MMD2_k127_436771_11 Belongs to the glycosyl hydrolase 57 family K07405 - 3.2.1.1 0.00004792 57.0
MMD2_k127_436771_2 Alpha amylase, catalytic domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 492.0
MMD2_k127_436771_3 Nucleotidyl transferase K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 413.0
MMD2_k127_436771_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 376.0
MMD2_k127_436771_5 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000006921 266.0
MMD2_k127_436771_6 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001035 249.0
MMD2_k127_436771_7 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000216 166.0
MMD2_k127_436771_8 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000596 141.0
MMD2_k127_4419293_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 602.0
MMD2_k127_4419293_1 PFAM RNA binding S1 domain protein K02945,K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000008724 264.0
MMD2_k127_4419293_2 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000074 231.0
MMD2_k127_4419293_3 N-terminal 7TM region of histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001181 216.0
MMD2_k127_4429725_0 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 516.0
MMD2_k127_4429725_1 periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 322.0
MMD2_k127_4429725_2 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000005134 159.0
MMD2_k127_4429725_3 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000007201 69.0
MMD2_k127_4429725_4 Amino acid permease - - - 0.0000000001345 74.0
MMD2_k127_44464_0 PFAM ABC transporter related K06147 - - 1.923e-236 745.0
MMD2_k127_44464_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004938 320.0
MMD2_k127_44464_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001829 258.0
MMD2_k127_44464_3 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000007676 232.0
MMD2_k127_44464_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000002201 209.0
MMD2_k127_44464_5 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000000000000000000000000397 198.0
MMD2_k127_44464_6 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000002003 177.0
MMD2_k127_4471402_0 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 396.0
MMD2_k127_4471402_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 296.0
MMD2_k127_4471402_2 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004598 240.0
MMD2_k127_4471402_3 sigma-70 region 2 domain protein K03088 - - 0.0000000000000000000000000000000000000000000000000000001783 201.0
MMD2_k127_4471402_4 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000003622 188.0
MMD2_k127_4471402_5 TIGRFAM sugar-phosphate isomerases, RpiB LacA LacB family K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000001698 166.0
MMD2_k127_4471402_6 Nudix hydrolase - - - 0.00000000000000000000000000000000000002114 156.0
MMD2_k127_4471402_8 Transglycosylase SLT domain - - - 0.00000000000003301 81.0
MMD2_k127_4471402_9 AntiSigma factor - - - 0.0000000000005972 79.0
MMD2_k127_4473193_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.002e-293 937.0
MMD2_k127_4473193_1 Serine threonine protein kinase K12132 - 2.7.11.1 8.174e-214 687.0
MMD2_k127_4473193_10 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 374.0
MMD2_k127_4473193_11 PFAM UbiA prenyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 346.0
MMD2_k127_4473193_12 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001819 285.0
MMD2_k127_4473193_13 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006953 276.0
MMD2_k127_4473193_14 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000143 273.0
MMD2_k127_4473193_15 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001099 267.0
MMD2_k127_4473193_16 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000000000000000000000000005239 239.0
MMD2_k127_4473193_17 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000001625 218.0
MMD2_k127_4473193_18 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000007869 219.0
MMD2_k127_4473193_19 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000093 205.0
MMD2_k127_4473193_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.344e-199 637.0
MMD2_k127_4473193_20 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0000049,GO:0001522,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0031119,GO:0034337,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000002522 201.0
MMD2_k127_4473193_21 GHMP kinases C terminal K00054,K00869,K01641 - 1.1.1.88,2.3.3.10,2.7.1.36 0.000000000000000000000000000000000000000000000000001929 195.0
MMD2_k127_4473193_22 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) - - - 0.0000000000000000000000000000000000000000000000006629 181.0
MMD2_k127_4473193_23 TIGRFAM small GTP-binding protein K06945 - - 0.000000000000000000000000000000000000001187 153.0
MMD2_k127_4473193_24 Belongs to the thioredoxin family K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.000000000000000000000000000000000000003663 148.0
MMD2_k127_4473193_25 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000004912 129.0
MMD2_k127_4473193_26 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000000000004659 119.0
MMD2_k127_4473193_27 PFAM Forkhead-associated protein - - - 0.000000000000000000000000007026 116.0
MMD2_k127_4473193_28 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000001913 100.0
MMD2_k127_4473193_29 - - - - 0.000000000000000000006827 95.0
MMD2_k127_4473193_3 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.579e-198 635.0
MMD2_k127_4473193_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004018 428.0
MMD2_k127_4473193_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 428.0
MMD2_k127_4473193_6 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003588 387.0
MMD2_k127_4473193_7 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 384.0
MMD2_k127_4473193_8 Two component transcriptional regulator, winged helix family K07667,K07668 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 370.0
MMD2_k127_4473193_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 380.0
MMD2_k127_4507022_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.939e-204 642.0
MMD2_k127_4507022_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 612.0
MMD2_k127_4507022_10 iron ion homeostasis K07165 - - 0.0005852 48.0
MMD2_k127_4507022_2 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 325.0
MMD2_k127_4507022_3 Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005057 256.0
MMD2_k127_4507022_4 Molydopterin dinucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 242.0
MMD2_k127_4507022_5 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000001532 153.0
MMD2_k127_4507022_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000002713 112.0
MMD2_k127_4507022_7 geranylgeranyl reductase activity - - - 0.0000000000000000000000004767 119.0
MMD2_k127_4507022_8 - - - - 0.0000501 55.0
MMD2_k127_4507022_9 - - - - 0.00006547 45.0
MMD2_k127_452291_0 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 355.0
MMD2_k127_452291_1 TIGRFAM channel protein, hemolysin III family K11068 - - 0.00000000000000000000000000000000000000000000000000000000002687 213.0
MMD2_k127_452291_2 lipid binding - - - 0.0000000000000000000000000000000000000000000000000223 191.0
MMD2_k127_452291_3 4Fe-4S dicluster domain - - - 0.0000000000000000000002352 100.0
MMD2_k127_452291_4 Encoded by - - - 0.00000000000000008517 87.0
MMD2_k127_4580492_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 555.0
MMD2_k127_4580492_1 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 364.0
MMD2_k127_4580492_2 Serine aminopeptidase, S33 K03928 - 3.1.1.1 0.0000000000000000000000000000000000000000000000000327 188.0
MMD2_k127_4580492_3 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000001029 178.0
MMD2_k127_4580492_4 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000005237 159.0
MMD2_k127_4580492_5 Acid phosphatase homologues - - - 0.0000000000000000000000000000000000000005726 158.0
MMD2_k127_4580492_7 Major facilitator superfamily - - - 0.00000000000000003269 94.0
MMD2_k127_4596519_0 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 434.0
MMD2_k127_4596519_1 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.00002545 50.0
MMD2_k127_4712331_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 514.0
MMD2_k127_4712331_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002696 463.0
MMD2_k127_4712331_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960,K20810 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0050270 3.5.4.28,3.5.4.31,3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 390.0
MMD2_k127_4712331_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 301.0
MMD2_k127_4712331_4 Peptidase M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001922 271.0
MMD2_k127_4712331_5 MFS/sugar transport protein K03292 - - 0.00000000000000000000000000000000000001103 161.0
MMD2_k127_4729364_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0 1354.0
MMD2_k127_4729364_1 Pyruvate:ferredoxin oxidoreductase core domain II K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 542.0
MMD2_k127_4729364_2 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008567 546.0
MMD2_k127_4729364_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 411.0
MMD2_k127_4729364_4 3'-5' exonuclease K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 323.0
MMD2_k127_4729364_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00177 - 1.2.7.1,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000001599 260.0
MMD2_k127_4729364_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000000000000000000005597 117.0
MMD2_k127_4729364_7 polysaccharide biosynthetic process - - - 0.00000000000000001216 96.0
MMD2_k127_4730832_0 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 451.0
MMD2_k127_4730832_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 420.0
MMD2_k127_4730832_10 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000002222 109.0
MMD2_k127_4730832_11 signal peptide peptidase SppA, 36K type K04773 - - 0.00000000005362 76.0
MMD2_k127_4730832_2 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 357.0
MMD2_k127_4730832_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 326.0
MMD2_k127_4730832_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 323.0
MMD2_k127_4730832_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000004282 256.0
MMD2_k127_4730832_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
MMD2_k127_4730832_7 Belongs to the CDS family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000007731 245.0
MMD2_k127_4730832_8 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000003409 219.0
MMD2_k127_4730832_9 serine-type peptidase activity K04773 - - 0.000000000000000000000000000000000000000198 161.0
MMD2_k127_4732115_0 Belongs to the pseudouridine synthase RsuA family K06178,K06181 - 5.4.99.20,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001757 280.0
MMD2_k127_4732115_1 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000000004651 189.0
MMD2_k127_4732115_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000004188 179.0
MMD2_k127_4779922_0 4Fe-4S double cluster binding domain K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006746 287.0
MMD2_k127_4779922_1 Rubrerythrin - - - 0.00000000000000000000000000000000000000000000000000000000949 203.0
MMD2_k127_4779922_2 COG COG0371 Glycerol dehydrogenase and related enzymes Energy production and conversion K00096 - 1.1.1.261 0.0000000000000000000000000000000000002613 146.0
MMD2_k127_4779922_4 Ferredoxin - - - 0.000000000000000000000006149 102.0
MMD2_k127_4781960_0 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 486.0
MMD2_k127_4781960_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 395.0
MMD2_k127_4781960_10 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000008411 106.0
MMD2_k127_4781960_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 325.0
MMD2_k127_4781960_3 Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway K16329 - 4.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 314.0
MMD2_k127_4781960_4 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009593 291.0
MMD2_k127_4781960_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001562 268.0
MMD2_k127_4781960_7 mRNA catabolic process K06950 - - 0.00000000000000000000000000000000000000000000000000002378 197.0
MMD2_k127_4781960_8 PFAM DSBA oxidoreductase - - - 0.0000000000000000000000000000000000000000000000003957 186.0
MMD2_k127_4781960_9 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000001637 122.0
MMD2_k127_4815455_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 3.787e-199 632.0
MMD2_k127_4815455_1 PHP domain protein K02347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 574.0
MMD2_k127_4815455_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 474.0
MMD2_k127_4815455_3 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 317.0
MMD2_k127_4815455_4 - - - - 0.0000000000001665 77.0
MMD2_k127_4821004_0 Tetratricopeptide TPR_2 repeat protein - - - 5.012e-251 815.0
MMD2_k127_4821004_1 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 451.0
MMD2_k127_4836643_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 433.0
MMD2_k127_4836643_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000002293 228.0
MMD2_k127_4836643_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000001656 63.0
MMD2_k127_4858037_0 Acyl- CoA dehydrogenase type 2 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 486.0
MMD2_k127_4858037_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005865 276.0
MMD2_k127_4858037_2 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000001364 245.0
MMD2_k127_4858037_3 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000001763 213.0
MMD2_k127_4868872_0 NTF2-like N-terminal transpeptidase domain K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000506 604.0
MMD2_k127_4868872_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 511.0
MMD2_k127_4868872_3 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 407.0
MMD2_k127_4868872_4 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000142 293.0
MMD2_k127_4868872_5 - - - - 0.0001671 49.0
MMD2_k127_4888770_0 Heavy-metal-associated domain K17686 - 3.6.3.54 9.231e-221 704.0
MMD2_k127_4888770_1 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 624.0
MMD2_k127_4888770_2 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 553.0
MMD2_k127_4888770_3 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 314.0
MMD2_k127_4888770_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000002874 212.0
MMD2_k127_4888770_5 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000005006 115.0
MMD2_k127_4940772_0 SMART AAA ATPase - - - 4.879e-207 652.0
MMD2_k127_4940772_1 PFAM phosphoesterase, RecJ domain protein K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 439.0
MMD2_k127_4940772_10 Ferric uptake regulator family K03711 - - 0.0000000000000000006011 92.0
MMD2_k127_4940772_11 - - - - 0.00000002527 63.0
MMD2_k127_4940772_2 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 326.0
MMD2_k127_4940772_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 307.0
MMD2_k127_4940772_4 Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001826 270.0
MMD2_k127_4940772_5 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000001445 244.0
MMD2_k127_4940772_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000000000000000000000000000000000000000000000000183 206.0
MMD2_k127_4940772_7 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000007711 192.0
MMD2_k127_4940772_8 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000000000000000000000000001765 182.0
MMD2_k127_4940772_9 Domain of unknown function (DUF4870) - - - 0.0000000000000000000000000001387 119.0
MMD2_k127_5031162_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 9.173e-310 970.0
MMD2_k127_5031162_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.317e-224 707.0
MMD2_k127_5031162_10 Modulates RecA activity K03565 - - 0.000000000000000000000000000000000000002636 156.0
MMD2_k127_5031162_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000002573 151.0
MMD2_k127_5031162_12 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000000000001099 118.0
MMD2_k127_5031162_13 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000004163 103.0
MMD2_k127_5031162_15 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000008374 82.0
MMD2_k127_5031162_16 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000008983 78.0
MMD2_k127_5031162_17 regulatory protein, FmdB family - - - 0.000000000002695 69.0
MMD2_k127_5031162_18 PFAM Tetratricopeptide repeat - - - 0.00001203 57.0
MMD2_k127_5031162_19 PFAM GGDEF domain containing protein - - - 0.0001226 49.0
MMD2_k127_5031162_2 Short-chain dehydrogenase reductase SDR - - - 1.903e-224 713.0
MMD2_k127_5031162_3 Endoribonuclease that initiates mRNA decay K18682 - - 1.341e-206 653.0
MMD2_k127_5031162_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 516.0
MMD2_k127_5031162_5 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 503.0
MMD2_k127_5031162_6 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006827 421.0
MMD2_k127_5031162_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 331.0
MMD2_k127_5031162_8 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 300.0
MMD2_k127_5031162_9 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000009476 250.0
MMD2_k127_5047759_0 PFAM metal-dependent phosphohydrolase, HD sub domain K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006133 535.0
MMD2_k127_5047759_1 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 411.0
MMD2_k127_5047759_10 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000003251 244.0
MMD2_k127_5047759_11 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001866 235.0
MMD2_k127_5047759_12 Redoxin K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000001461 220.0
MMD2_k127_5047759_13 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000000000000000000000004952 222.0
MMD2_k127_5047759_14 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000000000000000000001212 195.0
MMD2_k127_5047759_15 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000006455 193.0
MMD2_k127_5047759_16 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000001723 186.0
MMD2_k127_5047759_17 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000005376 159.0
MMD2_k127_5047759_18 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000002823 162.0
MMD2_k127_5047759_19 Phosphomethylpyrimidine kinase K00882,K00917 - 2.7.1.144,2.7.1.56 0.00000000000000000000000000000000000000003082 164.0
MMD2_k127_5047759_2 PFAM Polynucleotide adenylyltransferase region K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 359.0
MMD2_k127_5047759_20 4-vinyl reductase, 4VR - - - 0.000000000000000000000000000000002089 138.0
MMD2_k127_5047759_21 Ribosomal L27 protein K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000005466 126.0
MMD2_k127_5047759_22 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000000000002736 122.0
MMD2_k127_5047759_23 Class ii aldolase K01628,K03077 - 4.1.2.17,5.1.3.4 0.000000000000000000000000002737 120.0
MMD2_k127_5047759_25 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000002284 102.0
MMD2_k127_5047759_26 Uncharacterised conserved protein (DUF2156) K14205 - 2.3.2.3 0.000002662 60.0
MMD2_k127_5047759_27 Transcriptional regulator - - - 0.000005499 57.0
MMD2_k127_5047759_3 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007578 334.0
MMD2_k127_5047759_4 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 329.0
MMD2_k127_5047759_5 TIGRFAM small GTP-binding protein K06945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 289.0
MMD2_k127_5047759_6 PFAM thymidine kinase K00857 GO:0003674,GO:0003824,GO:0004797,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006259,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009120,GO:0009123,GO:0009124,GO:0009157,GO:0009162,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019136,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046104,GO:0046125,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0090304,GO:0090407,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008327 273.0
MMD2_k127_5047759_7 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002133 269.0
MMD2_k127_5047759_8 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 257.0
MMD2_k127_5047759_9 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000001257 244.0
MMD2_k127_5103347_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.623e-284 888.0
MMD2_k127_5103347_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 3.791e-239 756.0
MMD2_k127_5103347_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 439.0
MMD2_k127_5103347_3 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 410.0
MMD2_k127_5103347_4 amino acid-binding ACT domain protein K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001331 245.0
MMD2_k127_5103347_5 Encoded by - - - 0.0000000000000000000000000000000000000000000000000001816 199.0
MMD2_k127_5103347_6 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000001527 138.0
MMD2_k127_5103347_7 Belongs to the N(4) N(6)-methyltransferase family K13581 - 2.1.1.72 0.000000313 55.0
MMD2_k127_510623_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 570.0
MMD2_k127_510623_1 ATPase associated with various cellular K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005492 431.0
MMD2_k127_510623_2 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001923 287.0
MMD2_k127_510623_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000006803 172.0
MMD2_k127_510623_4 Protein of unknown function (DUF456) K09793 - - 0.0000000000000000000000006354 110.0
MMD2_k127_510623_5 GIY-YIG catalytic domain - - - 0.0000001598 52.0
MMD2_k127_5112063_0 PFAM band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 434.0
MMD2_k127_5112063_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 330.0
MMD2_k127_5112063_2 PFAM regulatory protein GntR HTH K07979 - - 0.000000000000000000000000000000001024 134.0
MMD2_k127_5112063_3 PFAM response regulator receiver - - - 0.00000000001935 68.0
MMD2_k127_5112063_4 CAAX protease self-immunity - - - 0.00006316 52.0
MMD2_k127_5112063_5 Domain of unknown function (DUF4177) - - - 0.0004591 45.0
MMD2_k127_5133103_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004041 320.0
MMD2_k127_5133103_1 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000004251 223.0
MMD2_k127_5133103_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000001134 184.0
MMD2_k127_5133103_3 COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit - - - 0.000000000000285 81.0
MMD2_k127_5133103_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 - - 0.00001179 52.0
MMD2_k127_5221815_0 GHMP kinases N terminal domain K01597 - 4.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 332.0
MMD2_k127_5221815_1 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001957 284.0
MMD2_k127_5221815_2 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002417 271.0
MMD2_k127_5221815_3 SMART PDZ DHR GLGF domain protein K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000002506 244.0
MMD2_k127_5221815_4 PFAM aspartate glutamate uridylate kinase K06981 - 2.7.4.26 0.0000000000000000000000000000000000000000000000000000000000000000001347 239.0
MMD2_k127_5221815_5 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000005371 218.0
MMD2_k127_5221815_6 PBS lyase HEAT domain protein repeat-containing protein - - - 0.000000000000000000000000000000000000000000000001993 189.0
MMD2_k127_5221815_7 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000007945 153.0
MMD2_k127_5221815_8 sh3 domain protein K01227,K03642 - 3.2.1.96 0.0000000000000000000000000000000000004996 158.0
MMD2_k127_5221815_9 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000000004315 101.0
MMD2_k127_5234419_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 4.379e-265 829.0
MMD2_k127_5234419_1 elongation factor Tu domain 2 protein K02355 - - 1.274e-245 771.0
MMD2_k127_5234419_2 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 479.0
MMD2_k127_5234419_3 Protein of unknown function (DUF971) - - - 0.0000000000000000000000001171 119.0
MMD2_k127_5255100_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 559.0
MMD2_k127_5255100_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 446.0
MMD2_k127_5255100_10 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000007001 240.0
MMD2_k127_5255100_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000005258 227.0
MMD2_k127_5255100_12 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000008357 226.0
MMD2_k127_5255100_13 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000002136 221.0
MMD2_k127_5255100_14 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000087 209.0
MMD2_k127_5255100_15 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002268 202.0
MMD2_k127_5255100_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001161 205.0
MMD2_k127_5255100_17 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002592 197.0
MMD2_k127_5255100_18 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002579 194.0
MMD2_k127_5255100_19 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000001544 188.0
MMD2_k127_5255100_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 426.0
MMD2_k127_5255100_20 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001676 177.0
MMD2_k127_5255100_21 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000001292 181.0
MMD2_k127_5255100_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000009007 164.0
MMD2_k127_5255100_23 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000001206 154.0
MMD2_k127_5255100_24 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000002168 153.0
MMD2_k127_5255100_25 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000004073 151.0
MMD2_k127_5255100_26 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000001872 153.0
MMD2_k127_5255100_27 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000001461 122.0
MMD2_k127_5255100_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000001584 102.0
MMD2_k127_5255100_29 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002944 94.0
MMD2_k127_5255100_3 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 431.0
MMD2_k127_5255100_30 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000005283 98.0
MMD2_k127_5255100_31 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000809 83.0
MMD2_k127_5255100_32 Ribosomal protein L30p/L7e K02907 - - 0.000000000000094 74.0
MMD2_k127_5255100_33 Belongs to the bacterial ribosomal protein bL36 family K02919 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000339 65.0
MMD2_k127_5255100_34 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000004807 68.0
MMD2_k127_5255100_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003928 318.0
MMD2_k127_5255100_5 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 293.0
MMD2_k127_5255100_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 290.0
MMD2_k127_5255100_7 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006696 281.0
MMD2_k127_5255100_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000001154 250.0
MMD2_k127_5255100_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000002954 246.0
MMD2_k127_5276411_0 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 507.0
MMD2_k127_5276411_1 Domain of unknown function (DUF4347) - - - 0.000000000000000000000006636 112.0
MMD2_k127_5338791_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012,K00066 - 1.1.1.132,1.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 322.0
MMD2_k127_5338791_1 Glycosyl transferase, family 2 K20444 - - 0.0000000000000000000000000000000000000000000000000000000000000000002994 242.0
MMD2_k127_5419693_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 296.0
MMD2_k127_5419693_1 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002885 274.0
MMD2_k127_5419693_2 transferase activity, transferring glycosyl groups K21011,K21012 - - 0.0000000000000000000000000000000000000000000000002754 191.0
MMD2_k127_5419693_3 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000005056 130.0
MMD2_k127_5423762_0 PFAM Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 385.0
MMD2_k127_5423762_1 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002836 255.0
MMD2_k127_5423762_2 Transposase - - - 0.000000000000000000000000000000000000007982 151.0
MMD2_k127_5423762_3 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000721 141.0
MMD2_k127_5423762_4 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000008375 136.0
MMD2_k127_5423762_5 Transcriptional regulator - - - 0.00000000000001083 81.0
MMD2_k127_5494223_0 Beta-eliminating lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 597.0
MMD2_k127_5494223_1 beta-lactamase domain protein - - - 0.0000000000000001451 88.0
MMD2_k127_5509041_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 308.0
MMD2_k127_5509041_1 PFAM Glycosyl hydrolase family 1 K01223,K05350 - 3.2.1.21,3.2.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000009301 268.0
MMD2_k127_5509041_2 phosphatidylinositol kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000193 228.0
MMD2_k127_5509041_3 Phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000001518 191.0
MMD2_k127_5509041_4 Protein of unknown function (DUF3090) - - - 0.0000000000000000000000000000000000000000000000002081 183.0
MMD2_k127_5519813_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 540.0
MMD2_k127_5519813_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 415.0
MMD2_k127_5519813_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000308 278.0
MMD2_k127_5519813_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000153 250.0
MMD2_k127_5519813_4 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000005663 243.0
MMD2_k127_5519813_5 isoprenoid biosynthetic process K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000001034 224.0
MMD2_k127_5519813_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000114 205.0
MMD2_k127_5519813_7 methyltransferase activity K00569 - 2.1.1.67 0.0000000000000000000000000000000001673 139.0
MMD2_k127_5526421_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain - - - 9.743e-226 709.0
MMD2_k127_5526421_1 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002366 325.0
MMD2_k127_5526421_2 Two component transcriptional regulator, winged helix family K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 292.0
MMD2_k127_5526421_3 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000006463 278.0
MMD2_k127_5526421_4 TIGRFAM phosphate ABC transporter, phosphate-binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000008736 243.0
MMD2_k127_5526421_5 maltose binding K02027,K15770 - - 0.00000000000000000000000000000000000000000000000007557 195.0
MMD2_k127_5526421_6 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000007514 171.0
MMD2_k127_5553343_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 477.0
MMD2_k127_5553343_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008951 413.0
MMD2_k127_5553343_2 PFAM type II secretion system protein E K02283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 401.0
MMD2_k127_5553343_3 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000203 172.0
MMD2_k127_5553343_4 - - - - 0.000000000000000000000000000000000000004796 150.0
MMD2_k127_5553343_5 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000001157 137.0
MMD2_k127_5553343_6 sequence-specific DNA binding - - - 0.000000000000000000000000000001631 134.0
MMD2_k127_5553343_7 - - - - 0.000000000000000002767 93.0
MMD2_k127_5553343_8 FR47-like protein K03789 - 2.3.1.128 0.00000001343 66.0
MMD2_k127_5553343_9 Protein of unknown function (DUF554) K07150 - - 0.0000001956 54.0
MMD2_k127_5565028_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 551.0
MMD2_k127_5565028_1 PFAM oxidoreductase, molybdopterin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004145 335.0
MMD2_k127_5565028_10 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000145 152.0
MMD2_k127_5565028_11 PFAM Cytochrome C assembly protein K02195 - - 0.000000000000000000000000000000000002059 140.0
MMD2_k127_5565028_12 zinc-ribbon domain - - - 0.0000000000000003043 85.0
MMD2_k127_5565028_13 - - - - 0.0000001161 64.0
MMD2_k127_5565028_2 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004522 304.0
MMD2_k127_5565028_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 313.0
MMD2_k127_5565028_4 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
MMD2_k127_5565028_5 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004017 272.0
MMD2_k127_5565028_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000003286 254.0
MMD2_k127_5565028_7 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000001825 193.0
MMD2_k127_5565028_8 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K02199 - - 0.000000000000000000000000000000000000000000002697 169.0
MMD2_k127_5565028_9 Metalloenzyme superfamily - - - 0.0000000000000000000000000000000000000000002116 173.0
MMD2_k127_5575170_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.027e-228 739.0
MMD2_k127_5575170_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 487.0
MMD2_k127_5575170_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000005702 256.0
MMD2_k127_5575170_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002094 254.0
MMD2_k127_5575170_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000001225 178.0
MMD2_k127_5575170_5 PFAM alpha amylase, catalytic K01176,K01187 - 3.2.1.1,3.2.1.20 0.000000000000000000000000000000000000000000001405 171.0
MMD2_k127_5575170_6 PspC domain K03973 - - 0.0000000000001695 73.0
MMD2_k127_5575170_7 - - - - 0.000000000002947 69.0
MMD2_k127_5575170_8 domain protein - - - 0.000004913 56.0
MMD2_k127_5624977_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 9.33e-218 679.0
MMD2_k127_5624977_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 559.0
MMD2_k127_5624977_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00004389 46.0
MMD2_k127_5624977_11 PFAM glycosyl transferase, family 51 - - - 0.000286 52.0
MMD2_k127_5624977_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 343.0
MMD2_k127_5624977_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 297.0
MMD2_k127_5624977_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000007086 224.0
MMD2_k127_5624977_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000001977 147.0
MMD2_k127_5624977_6 THIoesterase K18700 - 3.1.2.29 0.000000000000000000000000000005322 124.0
MMD2_k127_5624977_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000006594 110.0
MMD2_k127_5624977_8 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000004132 98.0
MMD2_k127_5624977_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.00000000004284 65.0
MMD2_k127_5709563_0 PFAM Methicillin resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 308.0
MMD2_k127_5709563_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000005421 222.0
MMD2_k127_5709563_2 PFAM Methicillin resistance protein - - - 0.000000000000000000000000000000000000000000000000000000009795 218.0
MMD2_k127_5709563_3 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769 - 5.2.1.8 0.0000000000000000000000000000000000000001342 164.0
MMD2_k127_5727016_0 FAD dependent oxidoreductase central domain K19191 - 1.5.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 629.0
MMD2_k127_5727016_1 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 377.0
MMD2_k127_5727016_2 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 305.0
MMD2_k127_5727016_3 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000004243 203.0
MMD2_k127_5727016_4 Choline/ethanolamine kinase - - - 0.00000000000000000000000000000000000000000000000000009471 197.0
MMD2_k127_5727016_5 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000009636 202.0
MMD2_k127_5727016_6 DeoR C terminal sensor domain - - - 0.00000000000000000000000000000000000000000000000002503 190.0
MMD2_k127_5727016_7 - - - - 0.0000000000000000000000000000000000000000000002781 179.0
MMD2_k127_5727016_8 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000006078 145.0
MMD2_k127_5727016_9 Domain in cystathionine beta-synthase and other proteins. K14446 - 1.3.1.85 0.00000000000000001402 93.0
MMD2_k127_5759219_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.384e-301 944.0
MMD2_k127_5759219_1 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 394.0
MMD2_k127_5759219_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 323.0
MMD2_k127_5759219_3 Molybdopterin-binding domain of aldehyde dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 303.0
MMD2_k127_5759219_4 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004156 276.0
MMD2_k127_5759219_5 CbbQ/NirQ/NorQ C-terminal K09882 - 6.6.1.2 0.000000000000000000000000000000000000000005477 166.0
MMD2_k127_5759219_6 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.000000000000000000000002342 106.0
MMD2_k127_5759219_7 Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide 5, 6-dimethylbenzimidazole phosphoribosyltransferase) K09883 - 6.6.1.2 0.00000000000002204 87.0
MMD2_k127_5767855_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1877.0
MMD2_k127_5767855_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1039.0
MMD2_k127_5767855_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000007075 258.0
MMD2_k127_5767855_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000000001043 232.0
MMD2_k127_5767855_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.00000000000000000000000000000000000000000000000000000001057 201.0
MMD2_k127_5767855_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000002684 73.0
MMD2_k127_5797062_0 Selenocysteine-specific translation elongation factor K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002595 619.0
MMD2_k127_5797062_1 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 451.0
MMD2_k127_5797062_2 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 334.0
MMD2_k127_5797062_3 peptidase - - - 0.00000000000002273 78.0
MMD2_k127_5846801_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 608.0
MMD2_k127_5846801_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 580.0
MMD2_k127_5846801_2 Aminotransferase K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 512.0
MMD2_k127_5846801_3 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 366.0
MMD2_k127_5846801_4 Trypsin-like peptidase domain K08372 - - 0.0000000000000000000000000000000001442 154.0
MMD2_k127_5846801_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000002115 99.0
MMD2_k127_5846801_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000001339 56.0
MMD2_k127_5846801_8 - - - - 0.0009181 45.0
MMD2_k127_5911334_0 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.0000000000000000000000000000000000000000000000000000000000000000002174 235.0
MMD2_k127_5911334_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000002961 216.0
MMD2_k127_5911334_2 Domain of unknown function (DUF4442) - - - 0.0000000000000000000000000000000000000000000000000000004217 199.0
MMD2_k127_5911334_3 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000000004823 197.0
MMD2_k127_5911334_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000005294 178.0
MMD2_k127_5911334_5 Uracil DNA glycosylase superfamily - - - 0.00000000000000000000000000000000000002348 150.0
MMD2_k127_5911334_6 - - - - 0.00000000000000000000000000000002058 129.0
MMD2_k127_5911334_7 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000000000601 117.0
MMD2_k127_5911334_8 Domain of unknown function (DUF1508) K09946 - - 0.000000000000000008116 92.0
MMD2_k127_5920175_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0 1104.0
MMD2_k127_5920175_1 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 400.0
MMD2_k127_5920175_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 397.0
MMD2_k127_5920175_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000003531 226.0
MMD2_k127_5920175_4 acyl-phosphate glycerol-3-phosphate acyltransferase activity K08591 - 2.3.1.15 0.0000000000000000000000000000000000001008 155.0
MMD2_k127_5921269_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 331.0
MMD2_k127_5921269_1 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 310.0
MMD2_k127_5921269_2 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000000000000000000000000000005087 161.0
MMD2_k127_5921269_3 Acetyltransferase (GNAT) domain K18816 - 2.3.1.82 0.00000000000000000000000000000000001446 140.0
MMD2_k127_5921269_4 WD40-like Beta Propeller Repeat K03641,K08676 - - 0.00000000000000006255 93.0
MMD2_k127_5921269_5 - - - - 0.00005202 55.0
MMD2_k127_5930556_0 Fe-S oxidoreductase - - - 2.764e-214 685.0
MMD2_k127_5930556_1 Uncharacterised ArCR, COG2043 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003442 289.0
MMD2_k127_5951071_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000004248 168.0
MMD2_k127_5951071_1 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000001152 164.0
MMD2_k127_5951071_2 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000254 124.0
MMD2_k127_5951071_3 TIGRFAM cysteine desulfurase family protein - - - 0.000000000000000000000000005344 113.0
MMD2_k127_5983994_0 PFAM peptidase M20 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009745 571.0
MMD2_k127_5983994_1 Immune inhibitor A peptidase M6 K09607 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 561.0
MMD2_k127_5983994_10 YhhN family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000001321 114.0
MMD2_k127_5983994_12 Domain of unknown function (DUF309) K09763 - - 0.000000000000001431 83.0
MMD2_k127_5983994_2 Immune inhibitor A peptidase M6 K09607 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 480.0
MMD2_k127_5983994_3 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 505.0
MMD2_k127_5983994_4 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 320.0
MMD2_k127_5983994_5 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 297.0
MMD2_k127_5983994_6 Domain of unknown function (DUF348) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000127 281.0
MMD2_k127_5983994_7 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000004134 247.0
MMD2_k127_5983994_8 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000000000000000000000002883 238.0
MMD2_k127_5983994_9 Putative cyclase K07130 - 3.5.1.9 0.000000000000000000000000000000000000000000000000000000002989 206.0
MMD2_k127_5995357_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 376.0
MMD2_k127_5995357_1 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 365.0
MMD2_k127_5995357_2 PFAM glycosyl transferase, family 51 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 344.0
MMD2_k127_5995357_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 293.0
MMD2_k127_5995357_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K14696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 292.0
MMD2_k127_5995357_5 Methylenetetrahydrofolate reductase K00297,K00547,K00548 - 1.5.1.20,2.1.1.10,2.1.1.13 0.0000000000000000000000000000001048 128.0
MMD2_k127_6001500_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 510.0
MMD2_k127_6001500_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 389.0
MMD2_k127_6001500_2 PFAM Monogalactosyldiacylglycerol synthase K03429 - 2.4.1.315 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 392.0
MMD2_k127_6001500_3 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 362.0
MMD2_k127_6001500_4 Beta-lactamase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 293.0
MMD2_k127_6001500_5 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005251 268.0
MMD2_k127_6001500_7 Bacterial protein of unknown function (DUF951) - - - 0.0000000000000000002023 93.0
MMD2_k127_6027012_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 2.138e-227 719.0
MMD2_k127_6027012_1 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 517.0
MMD2_k127_6027012_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 440.0
MMD2_k127_6027012_3 FCD domain - - - 0.000000000000000000000000000000000000000000000000000000000386 209.0
MMD2_k127_6027012_4 PFAM periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000008611 212.0
MMD2_k127_6027012_5 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000003504 199.0
MMD2_k127_6038267_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 8.016e-282 884.0
MMD2_k127_6038267_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.595e-251 802.0
MMD2_k127_6038267_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00122,K00335 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 522.0
MMD2_k127_6038267_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 454.0
MMD2_k127_6038267_4 formate dehydrogenase (NAD+) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 325.0
MMD2_k127_6038267_5 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.000000000000000000002878 94.0
MMD2_k127_6045023_0 PFAM ABC transporter related K09691 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000597 435.0
MMD2_k127_6045023_1 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 408.0
MMD2_k127_6045023_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 317.0
MMD2_k127_6045023_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000008324 169.0
MMD2_k127_6045023_4 Cytidylyltransferase K00983 - 2.7.7.43 0.000000000000000000000002961 111.0
MMD2_k127_6113978_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 492.0
MMD2_k127_6113978_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000001901 269.0
MMD2_k127_6113978_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000001152 208.0
MMD2_k127_6113978_3 - - - - 0.000000000000000000000000000000000000000000000004114 178.0
MMD2_k127_6113978_4 regulatory protein, arsR - - - 0.0000000000000000000000009184 107.0
MMD2_k127_6113978_5 Nuclease-related domain - - - 0.00000000000000000001113 101.0
MMD2_k127_6113978_6 heme a metabolic process K02257,K02259 - 2.5.1.141 0.000000000004123 74.0
MMD2_k127_619226_0 hydroxyacid-oxoacid transhydrogenase activity K00001,K01714 - 1.1.1.1,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 409.0
MMD2_k127_619226_1 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000002848 111.0
MMD2_k127_619226_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000004889 104.0
MMD2_k127_619226_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000007519 73.0
MMD2_k127_6215661_0 PFAM natural resistance-associated macrophage protein K03322 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 581.0
MMD2_k127_6215661_1 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 242.0
MMD2_k127_6215661_2 conserved protein (DUF2156) K07027,K14205 - 2.3.2.3 0.00000000000000000000000000000000000001443 149.0
MMD2_k127_6215661_3 Cupin domain - - - 0.000000000000000009972 83.0
MMD2_k127_649260_0 rRNA (adenine-N6,N6-)-dimethyltransferase activity K00561,K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182,2.1.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000002581 258.0
MMD2_k127_649260_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000004192 226.0
MMD2_k127_649260_2 lysyltransferase activity K07027 - - 0.0000000000006179 77.0
MMD2_k127_649260_3 - - - - 0.000004239 55.0
MMD2_k127_684914_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 550.0
MMD2_k127_72665_0 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 548.0
MMD2_k127_72665_1 PFAM glycoside hydrolase, family 1 K05350 - 3.2.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 551.0
MMD2_k127_72665_10 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000005017 88.0
MMD2_k127_72665_11 Regulatory protein - - - 0.0000000003452 63.0
MMD2_k127_72665_12 Protein of unknown function (DUF459) - - - 0.00003639 55.0
MMD2_k127_72665_13 FR47-like protein - - - 0.0005507 51.0
MMD2_k127_72665_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III domain protein K01641 - 2.3.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 496.0
MMD2_k127_72665_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 474.0
MMD2_k127_72665_4 Family of unknown function (DUF5305) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000341 293.0
MMD2_k127_72665_5 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000000000000007312 201.0
MMD2_k127_72665_6 PFAM phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000001326 176.0
MMD2_k127_72665_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000002332 154.0
MMD2_k127_72665_8 LysM domain K07273,K22278 - 3.5.1.104 0.0000000000000000000007692 107.0
MMD2_k127_72665_9 - - - - 0.00000000000000000006045 94.0
MMD2_k127_731083_0 PFAM single-stranded nucleic acid binding R3H domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006172 481.0
MMD2_k127_731083_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 468.0
MMD2_k127_731083_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000001206 253.0
MMD2_k127_731083_11 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000009243 237.0
MMD2_k127_731083_12 PFAM Rhomboid family protein K19225 - 3.4.21.105 0.0000000000000000000000000000000000000000000002166 184.0
MMD2_k127_731083_13 Putative regulatory protein - - - 0.000000000000000000000000000000000005533 151.0
MMD2_k127_731083_14 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000002619 145.0
MMD2_k127_731083_16 Proton-conducting membrane transporter - - - 0.0000000000000000005903 100.0
MMD2_k127_731083_2 PFAM luciferase family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 376.0
MMD2_k127_731083_3 histidine kinase A domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 381.0
MMD2_k127_731083_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 362.0
MMD2_k127_731083_5 Belongs to the UPF0173 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 326.0
MMD2_k127_731083_6 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006003 276.0
MMD2_k127_731083_7 FES K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 267.0
MMD2_k127_731083_8 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000002913 256.0
MMD2_k127_731083_9 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007425 278.0
MMD2_k127_73660_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 530.0
MMD2_k127_73660_1 PFAM IstB domain protein ATP-binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 517.0
MMD2_k127_73660_10 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000005279 250.0
MMD2_k127_73660_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000009816 199.0
MMD2_k127_73660_12 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000001411 191.0
MMD2_k127_73660_13 TIGRFAM primosome, DnaD subunit - - - 0.000000000000000000000000000000000000003535 154.0
MMD2_k127_73660_14 - - - - 0.0000000000000000000000009449 115.0
MMD2_k127_73660_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 509.0
MMD2_k127_73660_3 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000568 461.0
MMD2_k127_73660_4 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003605 417.0
MMD2_k127_73660_5 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 409.0
MMD2_k127_73660_6 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 406.0
MMD2_k127_73660_7 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 364.0
MMD2_k127_73660_8 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 348.0
MMD2_k127_73660_9 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004714 280.0
MMD2_k127_785658_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 9.593e-211 662.0
MMD2_k127_785658_1 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002037 268.0
MMD2_k127_785658_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000009422 172.0
MMD2_k127_785658_3 exodeoxyribonuclease I activity - - - 0.00000000000000000000000000000000000000000697 166.0
MMD2_k127_785658_4 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0009135 49.0
MMD2_k127_790192_0 VWA domain containing CoxE-like protein K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 614.0
MMD2_k127_790192_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 495.0
MMD2_k127_790192_10 PFAM zinc finger, SWIM domain protein - - - 0.000000000000000000000000004672 113.0
MMD2_k127_790192_2 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 460.0
MMD2_k127_790192_3 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 415.0
MMD2_k127_790192_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 402.0
MMD2_k127_790192_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 359.0
MMD2_k127_790192_6 energy transducer activity K03531,K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002323 347.0
MMD2_k127_790192_7 PFAM Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000001059 236.0
MMD2_k127_790192_8 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000001009 224.0
MMD2_k127_827081_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 523.0
MMD2_k127_827081_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 429.0
MMD2_k127_827081_2 heterodisulfide reductase K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 424.0
MMD2_k127_827081_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 333.0
MMD2_k127_827081_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 312.0
MMD2_k127_827081_5 CobQ/CobB/MinD/ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000164 287.0
MMD2_k127_827081_6 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004363 286.0
MMD2_k127_827081_7 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000001342 187.0
MMD2_k127_827451_0 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000003199 214.0
MMD2_k127_827451_1 Nacht domain K13730 - - 0.0000000000000000000000000000000000000000000000000000001563 220.0
MMD2_k127_827451_2 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.00000000000002552 81.0
MMD2_k127_85971_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 497.0
MMD2_k127_85971_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 389.0
MMD2_k127_85971_2 Protein of unknown function (DUF2905) - - - 0.00000005602 57.0
MMD2_k127_864896_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 385.0
MMD2_k127_864896_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000001757 211.0
MMD2_k127_864896_2 Nacht domain - - - 0.0000000000000000000006784 113.0
MMD2_k127_864896_3 - - - - 0.000000000003997 70.0
MMD2_k127_900692_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000002508 240.0
MMD2_k127_900692_1 - - - - 0.00000000000000000000000244 107.0
MMD2_k127_900692_2 YbaB/EbfC DNA-binding family K06187,K09747 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0097159,GO:1901363 - 0.0000000000000000003253 97.0
MMD2_k127_900692_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0001157 50.0
MMD2_k127_927998_0 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 421.0
MMD2_k127_927998_1 Methionine synthase B12-binding module cap domain protein K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 396.0
MMD2_k127_927998_2 methylenetetrahydrofolate reductase (NAD(P)H) activity K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000001737 136.0
MMD2_k127_927998_3 ATP-dependent helicase deoxyribonuclease subunit B K16899 - 3.6.4.12 0.000000000000003479 90.0
MMD2_k127_952506_0 PFAM NADH-Ubiquinone oxidoreductase (complex I), chain 5 L domain protein K00341 - 1.6.5.3 7.982e-308 958.0
MMD2_k127_952506_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 2.001e-203 643.0
MMD2_k127_952506_10 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000002005 154.0
MMD2_k127_952506_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000000000000002359 134.0
MMD2_k127_952506_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000002878 123.0
MMD2_k127_952506_13 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000005476 135.0
MMD2_k127_952506_14 response regulator K02282,K07705 - - 0.00000000000000000000000008402 114.0
MMD2_k127_952506_15 integral membrane protein - - - 0.0000000000000000000003438 100.0
MMD2_k127_952506_16 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000199 106.0
MMD2_k127_952506_17 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000000000000001889 96.0
MMD2_k127_952506_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000002021 92.0
MMD2_k127_952506_19 luxR family - - - 0.000000000009657 66.0
MMD2_k127_952506_2 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 610.0
MMD2_k127_952506_20 PFAM CheB methylesterase K13924 - 2.1.1.80,3.1.1.61 0.0001579 50.0
MMD2_k127_952506_23 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0009684 46.0
MMD2_k127_952506_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006247 556.0
MMD2_k127_952506_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 424.0
MMD2_k127_952506_5 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 366.0
MMD2_k127_952506_6 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 340.0
MMD2_k127_952506_7 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 313.0
MMD2_k127_952506_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001115 248.0
MMD2_k127_952506_9 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000001687 182.0
MMD2_k127_989943_0 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006993 388.0
MMD2_k127_989943_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 362.0
MMD2_k127_989943_10 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000001329 175.0
MMD2_k127_989943_11 Protein of unknown function (DUF402) K07586 - - 0.000000000000000000003713 98.0
MMD2_k127_989943_12 PFAM basic membrane lipoprotein K07335 - - 0.000000000000000893 89.0
MMD2_k127_989943_2 TIGRFAM cell envelope-related function transcriptional attenuator, LytR CpsA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 367.0
MMD2_k127_989943_3 Fumarase C-terminus K01676,K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002579 302.0
MMD2_k127_989943_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002595 283.0
MMD2_k127_989943_5 PFAM peptidase C60, sortase A and B K07284 - 3.4.22.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002939 277.0
MMD2_k127_989943_6 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000000000000000000001228 233.0
MMD2_k127_989943_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000001913 219.0
MMD2_k127_989943_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000265 198.0
MMD2_k127_989943_9 Predicted membrane protein (DUF2085) - - - 0.000000000000000000000000000000000000000000000002254 184.0
MMD2_k127_999611_0 membrane protein involved in D-alanine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001711 273.0
MMD2_k127_999611_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000001078 104.0
MMD2_k127_999611_2 Sulfotransferase domain - - - 0.0000001945 58.0
MMD2_k127_999611_3 Non-ribosomal peptide synthetase modules and related proteins - - - 0.0000002285 57.0
MMD2_k127_999611_4 Sulfotransferase domain - - - 0.000002217 58.0
MMD2_k127_999611_5 lipolytic protein G-D-S-L family - - - 0.00000308 59.0
MMD2_k127_999611_6 Phosphopantetheine attachment site - - - 0.00008835 48.0