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Overview

ID MAG02372
Name MMD2_bin.4
Sample SMP0059
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA6898
Genus UBA6898
Species
Assembly information
Completeness (%) 77.58
Contamination (%) 2.11
GC content (%) 54.0
N50 (bp) 7,077
Genome size (bp) 1,981,092

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2043

Gene name Description KEGG GOs EC E-value Score Sequence
MMD2_k127_1001873_0 Alanine-glyoxylate amino-transferase K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 502.0
MMD2_k127_1001873_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000002787 208.0
MMD2_k127_1001873_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000001389 205.0
MMD2_k127_1001873_3 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000003256 113.0
MMD2_k127_1001873_5 - - - - 0.000000000007118 67.0
MMD2_k127_1001873_6 ABC transporter substrate binding protein K01989 - - 0.00000000002419 74.0
MMD2_k127_1025221_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 598.0
MMD2_k127_1025221_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 582.0
MMD2_k127_1025221_10 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001756 288.0
MMD2_k127_1025221_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000002467 258.0
MMD2_k127_1025221_12 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000006272 251.0
MMD2_k127_1025221_13 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000001528 207.0
MMD2_k127_1025221_14 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000001304 212.0
MMD2_k127_1025221_15 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000007104 193.0
MMD2_k127_1025221_16 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000009075 173.0
MMD2_k127_1025221_17 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000003536 153.0
MMD2_k127_1025221_18 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.0000000000000000000000000000000000239 140.0
MMD2_k127_1025221_19 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000003731 103.0
MMD2_k127_1025221_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 578.0
MMD2_k127_1025221_20 Protein of unknown function (DUF2905) - - - 0.000000000000000001936 90.0
MMD2_k127_1025221_21 Polymer-forming cytoskeletal - - - 0.000000000000000003496 89.0
MMD2_k127_1025221_22 - - - - 0.00000000000006646 73.0
MMD2_k127_1025221_23 - - - - 0.00000000001283 68.0
MMD2_k127_1025221_24 - - - - 0.00000002735 61.0
MMD2_k127_1025221_25 Fibronectin type 3 domain-containing protein K06882 - - 0.00000003242 65.0
MMD2_k127_1025221_26 Lipoprotein - - - 0.0000006639 59.0
MMD2_k127_1025221_3 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006769 494.0
MMD2_k127_1025221_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 481.0
MMD2_k127_1025221_5 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 452.0
MMD2_k127_1025221_6 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 348.0
MMD2_k127_1025221_7 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 340.0
MMD2_k127_1025221_8 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 336.0
MMD2_k127_1025221_9 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 298.0
MMD2_k127_1026871_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004113 413.0
MMD2_k127_1026871_1 endonuclease III K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004716 287.0
MMD2_k127_1026871_2 ATPase (AAA superfamily) K06923 - - 0.000000000000000000000000000000000000000000000000000006408 196.0
MMD2_k127_1026871_3 TIGRFAM mutator mutT protein K03574 - 3.6.1.55 0.0000000000000000000000000000000002365 136.0
MMD2_k127_1026871_4 Thioredoxin K03672 - 1.8.1.8 0.000000000000000000000000004773 116.0
MMD2_k127_1038771_0 DNA polymerase K02337 GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006260,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009360,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032991,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044776,GO:0046483,GO:0061695,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.0 1118.0
MMD2_k127_1038771_1 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005499 420.0
MMD2_k127_1038771_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 374.0
MMD2_k127_1038771_3 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005329 249.0
MMD2_k127_1038771_4 - - - - 0.0000000000000000000000000000000000000000000000001535 179.0
MMD2_k127_1038771_6 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000002336 66.0
MMD2_k127_1040397_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 8.535e-258 812.0
MMD2_k127_1040397_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.241e-230 728.0
MMD2_k127_1040397_2 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000008008 154.0
MMD2_k127_1040397_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000001036 141.0
MMD2_k127_1040397_4 Glu-tRNAGln amidotransferase C subunit K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000157 111.0
MMD2_k127_1040397_5 Trypsin K04771 - 3.4.21.107 0.000001483 52.0
MMD2_k127_1054537_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 408.0
MMD2_k127_1054537_1 MatE K03327 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 357.0
MMD2_k127_1054537_2 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 355.0
MMD2_k127_1054537_3 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000505 168.0
MMD2_k127_1054537_4 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.0000000000002304 81.0
MMD2_k127_1054537_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0001564 51.0
MMD2_k127_1064676_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.782e-261 822.0
MMD2_k127_1064676_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 321.0
MMD2_k127_1064676_2 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000003075 214.0
MMD2_k127_1064676_3 Cold-shock DNA-binding domain protein K03704 - - 0.0000000000000000002851 87.0
MMD2_k127_1064676_4 - - - - 0.0000000000001414 73.0
MMD2_k127_1067819_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 376.0
MMD2_k127_1067819_1 metal ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000003246 240.0
MMD2_k127_1067819_2 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.000000000000000000000000000000000000000000005651 166.0
MMD2_k127_1079309_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 504.0
MMD2_k127_1079309_1 Protein of unknown function (DUF512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 436.0
MMD2_k127_1079309_10 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000000000000000000000000007357 185.0
MMD2_k127_1079309_11 OstA-like protein K09774 - - 0.0000000000000000000000000000000003526 136.0
MMD2_k127_1079309_12 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000006647 134.0
MMD2_k127_1079309_13 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000001346 131.0
MMD2_k127_1079309_14 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000001136 98.0
MMD2_k127_1079309_15 PFAM EamA-like transporter family - - - 0.00000000000000000315 94.0
MMD2_k127_1079309_16 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.000004995 55.0
MMD2_k127_1079309_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 333.0
MMD2_k127_1079309_3 PFAM ABC transporter related K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002377 295.0
MMD2_k127_1079309_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 290.0
MMD2_k127_1079309_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001371 282.0
MMD2_k127_1079309_6 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001127 261.0
MMD2_k127_1079309_7 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000163 255.0
MMD2_k127_1079309_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000005744 241.0
MMD2_k127_1079309_9 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000479 201.0
MMD2_k127_1080618_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 568.0
MMD2_k127_1080618_1 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000006109 233.0
MMD2_k127_1137619_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02652 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 541.0
MMD2_k127_1137619_1 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007647 342.0
MMD2_k127_1137619_2 Bacterial type II and III secretion system protein K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 353.0
MMD2_k127_1137619_3 protein secretion K02460 - - 0.00000000000000000000000000000000003424 148.0
MMD2_k127_1137619_4 Pilus assembly protein K02461,K02662,K02663,K12289 - - 0.00000105 61.0
MMD2_k127_1142661_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 374.0
MMD2_k127_1153482_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 553.0
MMD2_k127_1153482_1 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 336.0
MMD2_k127_1153482_2 4Fe-4S binding domain - - - 0.00000000000000001188 83.0
MMD2_k127_1153482_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000002121 80.0
MMD2_k127_1153482_4 DsrE/DsrF-like family K07235 - - 0.0000000004131 65.0
MMD2_k127_1153482_5 energy transducer activity K03832 - - 0.0000000005357 67.0
MMD2_k127_1153482_6 sulfur carrier activity - - - 0.000000002785 61.0
MMD2_k127_1153482_7 Belongs to the DsrF TusC family K07236 - - 0.000004655 54.0
MMD2_k127_1173901_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 505.0
MMD2_k127_1173901_1 Transposase IS200 like - - - 0.00000000000000000000001505 105.0
MMD2_k127_1204535_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007092 593.0
MMD2_k127_1204535_1 biosynthesis glycosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001229 267.0
MMD2_k127_1204919_0 PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 401.0
MMD2_k127_1204919_1 Low affinity iron permease - - - 0.0000000000000000000000000000000000000000000000001547 180.0
MMD2_k127_1204919_2 Transglycosylase associated protein - - - 0.000000000000000000000000000000501 127.0
MMD2_k127_1217416_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 332.0
MMD2_k127_1217416_1 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000197 241.0
MMD2_k127_1217416_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000001689 75.0
MMD2_k127_1220202_0 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 515.0
MMD2_k127_1220202_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 446.0
MMD2_k127_1220202_10 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000001932 92.0
MMD2_k127_1220202_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 419.0
MMD2_k127_1220202_3 Transcriptional regulator K11921,K19338 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 383.0
MMD2_k127_1220202_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 352.0
MMD2_k127_1220202_5 aldolase class II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 288.0
MMD2_k127_1220202_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000001729 265.0
MMD2_k127_1220202_7 Aspartyl-tRNA amidotransferase K09117 - - 0.0000000000000000000000000000000000001752 145.0
MMD2_k127_1220202_8 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000004144 149.0
MMD2_k127_1220202_9 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000005024 99.0
MMD2_k127_1239134_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 551.0
MMD2_k127_1239134_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000002045 166.0
MMD2_k127_1261401_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 573.0
MMD2_k127_1261401_1 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000003634 181.0
MMD2_k127_1261401_2 Belongs to the P(II) protein family K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000000000001841 173.0
MMD2_k127_1261401_3 exo-alpha-(2->6)-sialidase activity - - - 0.0001445 54.0
MMD2_k127_1264376_0 cell redox homeostasis - - - 1.511e-214 676.0
MMD2_k127_1264376_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 316.0
MMD2_k127_1264376_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002781 282.0
MMD2_k127_1264376_3 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000002293 267.0
MMD2_k127_1264376_4 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000001041 192.0
MMD2_k127_1281277_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000792 246.0
MMD2_k127_1281277_2 transcriptional K03892 - - 0.00000000000004352 74.0
MMD2_k127_1285624_0 Histidine kinase A domain protein K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000365 240.0
MMD2_k127_1285624_1 - - - - 0.00000000000000000000000000000000000001094 148.0
MMD2_k127_1285624_2 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.00000000000000000000000000001303 120.0
MMD2_k127_1285624_3 response to heat K07090 - - 0.00000000000000000000000000007115 117.0
MMD2_k127_1285624_4 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000000003158 114.0
MMD2_k127_1285624_5 PFAM histidine kinase, HAMP region domain protein - - - 0.000000000000000000000009572 112.0
MMD2_k127_1288665_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1163.0
MMD2_k127_1288665_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006427 513.0
MMD2_k127_1288665_2 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 366.0
MMD2_k127_1288665_3 May be involved in the formation or repair of Fe-S clusters present in iron-sulfur proteins K13819 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 356.0
MMD2_k127_1288665_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000006223 237.0
MMD2_k127_1288665_5 GYD domain - - - 0.00000000000000000000000000000000005762 136.0
MMD2_k127_1288665_6 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000006451 109.0
MMD2_k127_1288665_7 sulfur carrier activity K04085 - - 0.00000000000000000003226 95.0
MMD2_k127_1289794_0 phosphorelay signal transduction system K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003817 277.0
MMD2_k127_1289794_1 Mo-molybdopterin cofactor metabolic process K02379 - - 0.000000000000000000000000000000000000000000000000000000000000001435 226.0
MMD2_k127_1289794_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000195 191.0
MMD2_k127_13060_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.17e-259 817.0
MMD2_k127_13060_1 PFAM PSP1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004601 247.0
MMD2_k127_13060_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000003463 221.0
MMD2_k127_13216_0 Polysaccharide export protein K01991 - - 0.000000000000000000000000000000000000000001041 171.0
MMD2_k127_13216_1 Bacterial type II and III secretion system protein K02453 - - 0.0000000000000000000000000001746 127.0
MMD2_k127_13216_2 G-rich domain on putative tyrosine kinase K16554 - - 0.000000004551 68.0
MMD2_k127_1323953_0 Polysulphide reductase, NrfD - - - 1.44e-196 620.0
MMD2_k127_1323953_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 551.0
MMD2_k127_1323953_10 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.0000000000000000000000000000006229 126.0
MMD2_k127_1323953_11 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000004142 132.0
MMD2_k127_1323953_12 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000000004688 77.0
MMD2_k127_1323953_13 PFAM cytoplasmic chaperone TorD family protein - - - 0.00000000004744 70.0
MMD2_k127_1323953_14 COG3005 Nitrate TMAO reductases, membrane-bound tetraheme cytochrome c subunit - - - 0.00001019 53.0
MMD2_k127_1323953_2 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 433.0
MMD2_k127_1323953_3 PFAM 4Fe-4S K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007124 435.0
MMD2_k127_1323953_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 337.0
MMD2_k127_1323953_5 PFAM VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000375 262.0
MMD2_k127_1323953_6 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000254 246.0
MMD2_k127_1323953_7 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000003807 204.0
MMD2_k127_1323953_8 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000008527 209.0
MMD2_k127_1323953_9 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000003264 160.0
MMD2_k127_1351224_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 578.0
MMD2_k127_1351224_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 440.0
MMD2_k127_1351224_10 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000003723 192.0
MMD2_k127_1351224_11 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000000000000000000000000000000000000000001872 171.0
MMD2_k127_1351224_12 PIN domain - - - 0.000000000000000000000000000000000000001377 150.0
MMD2_k127_1351224_13 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000008398 132.0
MMD2_k127_1351224_14 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.00000000000000001373 91.0
MMD2_k127_1351224_15 SpoVT / AbrB like domain - - - 0.000000000000006655 76.0
MMD2_k127_1351224_16 - - - - 0.00000000005533 64.0
MMD2_k127_1351224_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 370.0
MMD2_k127_1351224_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 352.0
MMD2_k127_1351224_4 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007619 333.0
MMD2_k127_1351224_5 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 330.0
MMD2_k127_1351224_6 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 311.0
MMD2_k127_1351224_7 PFAM cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 310.0
MMD2_k127_1351224_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 285.0
MMD2_k127_1351224_9 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000006996 229.0
MMD2_k127_1356712_0 Cytochrome C and Quinol oxidase polypeptide I K04561 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0016966,GO:0055114 1.7.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 398.0
MMD2_k127_1356712_1 PFAM Cytochrome b5 - - - 0.0000000000000000000000000000000000000000009 164.0
MMD2_k127_1356712_2 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000001294 141.0
MMD2_k127_1369852_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1094.0
MMD2_k127_1369852_1 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000006926 197.0
MMD2_k127_1374101_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 580.0
MMD2_k127_1374101_1 haloacid dehalogenase-like hydrolase K07026 - 3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 310.0
MMD2_k127_1374101_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000002636 223.0
MMD2_k127_1374101_3 phosphorelay signal transduction system - - - 0.0000000000000000000000009624 109.0
MMD2_k127_1374101_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000001288 90.0
MMD2_k127_1496451_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000000000000005832 211.0
MMD2_k127_1496451_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000001896 184.0
MMD2_k127_1496451_2 4 iron, 4 sulfur cluster binding - - - 0.000000000009499 67.0
MMD2_k127_1505916_0 Acetyl-coenzyme A transporter 1 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009807 580.0
MMD2_k127_1505916_1 TIGRFAM PAS domain S-box - - - 0.000000000000000000000000000000000000000000000000000000000000002504 238.0
MMD2_k127_1505916_2 Protein of unknown function (DUF1460) - - - 0.000000000000000000000000000000000000002474 151.0
MMD2_k127_1508366_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 441.0
MMD2_k127_1508366_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000386 251.0
MMD2_k127_1508366_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.00000000000000000000000000000000000000000000000000000000000003515 221.0
MMD2_k127_1508366_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000000000000007928 188.0
MMD2_k127_1508366_4 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000001804 120.0
MMD2_k127_155461_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 3.5e-293 915.0
MMD2_k127_155461_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 517.0
MMD2_k127_155461_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000006306 248.0
MMD2_k127_157953_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 8.814e-201 631.0
MMD2_k127_157953_1 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 548.0
MMD2_k127_157953_2 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 390.0
MMD2_k127_157953_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 328.0
MMD2_k127_157953_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000003943 271.0
MMD2_k127_157953_5 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000001106 235.0
MMD2_k127_157953_6 3-beta hydroxysteroid dehydrogenase isomerase - - - 0.00000000000000000000000000000000000000000008882 173.0
MMD2_k127_157953_7 phosphorelay signal transduction system - - - 0.000000000000001184 81.0
MMD2_k127_157953_8 Helix-turn-helix domain - - - 0.000000000000137 81.0
MMD2_k127_157953_9 DnaJ molecular chaperone homology domain - - - 0.0001651 54.0
MMD2_k127_1597577_0 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 474.0
MMD2_k127_1597577_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 418.0
MMD2_k127_1597577_2 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 366.0
MMD2_k127_1597577_3 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002149 269.0
MMD2_k127_1597577_4 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000204 245.0
MMD2_k127_1607504_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.551e-227 711.0
MMD2_k127_1607504_1 domain protein - - - 0.000000000000000000000001573 111.0
MMD2_k127_1607504_2 YtxH-like protein - - - 0.0000000000001162 72.0
MMD2_k127_1607504_3 EVE domain - - - 0.00000000001444 67.0
MMD2_k127_1610927_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 4.725e-234 746.0
MMD2_k127_1611414_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 457.0
MMD2_k127_1611414_1 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000001258 210.0
MMD2_k127_1611414_2 YGGT family K02221 - - 0.0000000000000000000000000000000009118 132.0
MMD2_k127_1611414_3 Conserved hypothetical protein 698 - - - 0.00000000000000000000000003686 119.0
MMD2_k127_1611414_4 HD domain - - - 0.0000000003122 70.0
MMD2_k127_1636108_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 335.0
MMD2_k127_1636108_1 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007269 297.0
MMD2_k127_1636108_2 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000000000000001066 163.0
MMD2_k127_1636108_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000000000000000003078 149.0
MMD2_k127_1636108_4 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine - - - 0.00000000000000004601 81.0
MMD2_k127_1636410_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1110.0
MMD2_k127_1636410_1 PFAM Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 499.0
MMD2_k127_1636410_2 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 328.0
MMD2_k127_1636410_3 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 302.0
MMD2_k127_1636410_4 Glycoprotease family K01409,K14742 GO:0002949,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000008427 197.0
MMD2_k127_1636410_5 response regulator - - - 0.0000000000000000000000000000000002519 144.0
MMD2_k127_1636410_6 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000007752 125.0
MMD2_k127_1636410_7 Regulatory protein, FmdB family - - - 0.000000146 55.0
MMD2_k127_1637335_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002926 410.0
MMD2_k127_1637335_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000007906 154.0
MMD2_k127_1637335_2 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000001007 150.0
MMD2_k127_1645429_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 385.0
MMD2_k127_1651311_0 GHKL domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007297 474.0
MMD2_k127_1651311_1 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001443 256.0
MMD2_k127_1651311_2 Histidine biosynthesis bifunctional protein HisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000003961 176.0
MMD2_k127_1651311_3 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.00000000000000000000000000000000000000000001271 165.0
MMD2_k127_1651311_4 Histidine biosynthesis bifunctional protein hisIE K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000005405 112.0
MMD2_k127_1658127_0 ABC transporter transmembrane region K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 525.0
MMD2_k127_1658127_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000408 412.0
MMD2_k127_1658127_10 Thiamine biosynthesis protein (ThiI) - - - 0.0001167 48.0
MMD2_k127_1658127_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 301.0
MMD2_k127_1658127_3 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007103 293.0
MMD2_k127_1658127_4 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000000000000000000000000000000000000000002348 235.0
MMD2_k127_1658127_5 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001919 225.0
MMD2_k127_1658127_6 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000000000001123 203.0
MMD2_k127_1658127_7 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000001053 183.0
MMD2_k127_1658127_8 Glycosyl transferase K20444 - - 0.000000000000000000000000003135 121.0
MMD2_k127_1658127_9 Glycosyl transferases group 1 - - - 0.0000000000000000169 94.0
MMD2_k127_1698361_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009197 599.0
MMD2_k127_1706165_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1069.0
MMD2_k127_1706165_1 Protein conserved in bacteria - - - 1.498e-221 713.0
MMD2_k127_1706165_10 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001606 282.0
MMD2_k127_1706165_11 PFAM PP-loop domain protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005468 269.0
MMD2_k127_1706165_12 Tetratricopeptide repeat K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001796 248.0
MMD2_k127_1706165_13 lactate metabolic process K11473,K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000001154 235.0
MMD2_k127_1706165_14 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000000000002025 207.0
MMD2_k127_1706165_15 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.0000000000000000000000000000000000000001387 158.0
MMD2_k127_1706165_2 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 6.517e-210 661.0
MMD2_k127_1706165_3 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 604.0
MMD2_k127_1706165_4 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 547.0
MMD2_k127_1706165_5 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002402 557.0
MMD2_k127_1706165_6 2Fe-2S iron-sulfur cluster binding domain K00240,K00245 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 412.0
MMD2_k127_1706165_7 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 328.0
MMD2_k127_1706165_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008488 282.0
MMD2_k127_1706165_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009584 278.0
MMD2_k127_1710882_0 Cytochrome bd terminal oxidase subunit I K00425 - 1.10.3.14 5.484e-209 657.0
MMD2_k127_1710882_1 Cytochrome bd terminal oxidase subunit II K00426 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 462.0
MMD2_k127_1710882_2 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009314 358.0
MMD2_k127_1710882_3 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005106 342.0
MMD2_k127_1710882_4 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000201 223.0
MMD2_k127_1710882_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000005089 198.0
MMD2_k127_1710882_6 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000002049 172.0
MMD2_k127_1710882_7 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000006491 141.0
MMD2_k127_1710882_8 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000000000000000005323 138.0
MMD2_k127_1710882_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000002334 80.0
MMD2_k127_1712423_0 anaerobic respiration - - - 0.0000000000000000000000000000000005598 139.0
MMD2_k127_1712423_1 elongation factor G K02355 - - 0.00000000000000000000001911 102.0
MMD2_k127_1712423_2 PFAM amidohydrolase - - - 0.00000000000000000001148 104.0
MMD2_k127_1712423_3 PFAM Rhodanese domain protein - - - 0.000000001519 62.0
MMD2_k127_1712423_4 - - - - 0.000000003056 60.0
MMD2_k127_1712423_5 Glutaredoxin - - - 0.000000007581 59.0
MMD2_k127_1712423_6 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000002485 59.0
MMD2_k127_1712423_7 PFAM Rhodanese domain protein - - - 0.0006651 42.0
MMD2_k127_1737826_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 300.0
MMD2_k127_1737826_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000008594 141.0
MMD2_k127_1737826_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000001185 93.0
MMD2_k127_1741967_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1661.0
MMD2_k127_1741967_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 2.409e-284 883.0
MMD2_k127_1741967_10 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000001235 123.0
MMD2_k127_1741967_11 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.00000000000000000000004163 103.0
MMD2_k127_1741967_12 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000009207 98.0
MMD2_k127_1741967_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.764e-203 640.0
MMD2_k127_1741967_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 1.381e-195 616.0
MMD2_k127_1741967_4 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 497.0
MMD2_k127_1741967_5 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000787 271.0
MMD2_k127_1741967_6 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000008783 254.0
MMD2_k127_1741967_7 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000003964 257.0
MMD2_k127_1741967_8 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000000009219 236.0
MMD2_k127_1741967_9 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000004622 208.0
MMD2_k127_1745705_1 - - - - 0.0000009923 55.0
MMD2_k127_1748028_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.253e-198 629.0
MMD2_k127_1748028_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002677 553.0
MMD2_k127_1748028_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 536.0
MMD2_k127_1748028_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003597 433.0
MMD2_k127_1748028_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 345.0
MMD2_k127_1748028_5 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000007235 182.0
MMD2_k127_1748028_6 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.0000000000000000000000000000788 116.0
MMD2_k127_1748028_7 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.00000000000008967 76.0
MMD2_k127_1748028_8 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000234 50.0
MMD2_k127_1777957_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 413.0
MMD2_k127_1777957_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000002688 195.0
MMD2_k127_1777957_2 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000005728 132.0
MMD2_k127_1777957_3 4Fe-4S binding domain - - - 0.0000000000000002949 84.0
MMD2_k127_1777957_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00005882 53.0
MMD2_k127_1835619_0 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 336.0
MMD2_k127_1884407_0 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 418.0
MMD2_k127_1884407_1 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000001475 179.0
MMD2_k127_1884407_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.00000000000000000000000000000000000000000000006058 176.0
MMD2_k127_1885112_0 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 541.0
MMD2_k127_1885112_1 Cytochrome c oxidase subunit K00404 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 512.0
MMD2_k127_1885112_10 - - - - 0.00008055 46.0
MMD2_k127_1885112_2 cytochrome c oxidase cbb3-type, subunit II K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 442.0
MMD2_k127_1885112_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 337.0
MMD2_k127_1885112_4 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 289.0
MMD2_k127_1885112_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000002929 241.0
MMD2_k127_1885112_6 Cytochrome c K08738 - - 0.000000000000000000000000000000000000000000000000000000000000000001513 230.0
MMD2_k127_1885112_7 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000002608 226.0
MMD2_k127_1885112_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000001048 142.0
MMD2_k127_1885112_9 part of a sulfur-relay system - - - 0.0000002252 56.0
MMD2_k127_1913718_0 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 390.0
MMD2_k127_1913718_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 340.0
MMD2_k127_1913718_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000003788 239.0
MMD2_k127_1913718_3 - - - - 0.000000000000000000000000000000000000000002249 165.0
MMD2_k127_1913718_4 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000004226 118.0
MMD2_k127_1928295_0 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 446.0
MMD2_k127_1928295_1 HAF family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 342.0
MMD2_k127_1928295_2 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 301.0
MMD2_k127_1928295_3 DJ-1/PfpI family K03152,K05520,K05687 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000002801 252.0
MMD2_k127_1928295_4 Protein of unknown function DUF262 - - - 0.0000000000000000000000000000000000000000001556 173.0
MMD2_k127_1928295_5 GAF domain K02584 - - 0.0000000000000000000000003741 108.0
MMD2_k127_1935653_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005244 409.0
MMD2_k127_1935653_1 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008855 343.0
MMD2_k127_1935653_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000002124 223.0
MMD2_k127_1935653_3 - - - - 0.00000000000000000000000006825 111.0
MMD2_k127_1951736_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 522.0
MMD2_k127_1951736_1 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 385.0
MMD2_k127_1951736_2 PFAM Fatty acid hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 327.0
MMD2_k127_1951736_3 Protein of unknown function (DUF3641) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009466 298.0
MMD2_k127_1951736_4 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.000000000000000000000000000000000000000000000000000000000001896 220.0
MMD2_k127_1951736_5 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000000000000000000000000004828 143.0
MMD2_k127_1983264_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 592.0
MMD2_k127_1983264_1 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 421.0
MMD2_k127_1983264_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000001516 264.0
MMD2_k127_1983264_3 Signal transduction histidine kinase, nitrogen specific, NtrB K07708 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000003955 221.0
MMD2_k127_1983264_4 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000002056 120.0
MMD2_k127_1983264_6 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00001512 48.0
MMD2_k127_1987971_0 PFAM V-type ATPase 116 kDa K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 576.0
MMD2_k127_1987971_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 533.0
MMD2_k127_1987971_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000000008177 108.0
MMD2_k127_1987971_11 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000003309 100.0
MMD2_k127_1987971_12 Protein of unknown function (DUF2892) - - - 0.0000000000002065 76.0
MMD2_k127_1987971_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 503.0
MMD2_k127_1987971_3 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007633 316.0
MMD2_k127_1987971_4 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000001884 221.0
MMD2_k127_1987971_5 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000008464 230.0
MMD2_k127_1987971_6 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000004557 162.0
MMD2_k127_1987971_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000002817 140.0
MMD2_k127_1987971_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000000002589 117.0
MMD2_k127_19974_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007503 331.0
MMD2_k127_19974_1 ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 337.0
MMD2_k127_19974_2 DUF218 domain - - - 0.000000000000000000009287 100.0
MMD2_k127_2028993_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1915.0
MMD2_k127_2028993_1 Beta-lactamase enzyme family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000004499 229.0
MMD2_k127_2028993_2 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000003885 216.0
MMD2_k127_2028993_3 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000000000256 115.0
MMD2_k127_2028993_4 Rubrerythrin - - - 0.00000000007693 63.0
MMD2_k127_2076810_0 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 587.0
MMD2_k127_2076810_1 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.00000000000000000000000000000000000000000000000000000000000005742 214.0
MMD2_k127_2076810_2 - - - - 0.000000000000000000000000000000000000000000000009582 179.0
MMD2_k127_2076810_3 - - - - 0.00000000000000000000000000000003485 129.0
MMD2_k127_2076810_4 - - - - 0.0004156 47.0
MMD2_k127_2092136_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006399 529.0
MMD2_k127_2092136_1 membrane K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 360.0
MMD2_k127_2092136_2 protein with SCP PR1 domains - - - 0.000000000000000000000000000000000000000000001344 172.0
MMD2_k127_2092136_3 - - - - 0.0000000000000000000000000000001001 132.0
MMD2_k127_2092136_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000002383 108.0
MMD2_k127_2092136_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.000000000000000000000001384 105.0
MMD2_k127_2092136_6 protein with SCP PR1 domains - - - 0.00000000000000000009428 91.0
MMD2_k127_2092136_7 - - - - 0.0000000000007571 71.0
MMD2_k127_2092136_8 Protein involved in outer membrane biogenesis K07289,K09800 - - 0.000001122 58.0
MMD2_k127_21080_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 480.0
MMD2_k127_21080_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000113 252.0
MMD2_k127_21080_2 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000000000000000000000582 159.0
MMD2_k127_21080_3 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000158 131.0
MMD2_k127_21080_4 PFAM Transglycosylase-associated protein - - - 0.0000000000000000000000000009858 114.0
MMD2_k127_21080_5 - - - - 0.000000000000000000003022 94.0
MMD2_k127_21080_6 Hemerythrin HHE cation binding domain - - - 0.0000000000000000005384 92.0
MMD2_k127_212487_0 ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 305.0
MMD2_k127_212487_1 photoreceptor activity K02007,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000002695 244.0
MMD2_k127_212487_2 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000006985 215.0
MMD2_k127_212487_3 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000001037 186.0
MMD2_k127_21394_0 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.0000000000000000000000000000000000000000001179 165.0
MMD2_k127_21394_1 Helix-hairpin-helix motif - - - 0.0000000000000000000000000000000000000001321 157.0
MMD2_k127_21394_2 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000234 151.0
MMD2_k127_2145410_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 330.0
MMD2_k127_2145410_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0008556,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015399,GO:0015405,GO:0015662,GO:0015672,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030001,GO:0030312,GO:0030955,GO:0031004,GO:0031224,GO:0031226,GO:0031420,GO:0032991,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043167,GO:0043169,GO:0043492,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0071944,GO:0090533,GO:0090662,GO:0098533,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009069 301.0
MMD2_k127_2145410_2 COG1233 Phytoene dehydrogenase and related - - - 0.00000000000007101 74.0
MMD2_k127_2180272_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002355 295.0
MMD2_k127_2180272_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002232 282.0
MMD2_k127_2180272_2 Sigma-70, region 4 K03088 - - 0.00000000000000000000000000000000000000000000000000000000002767 211.0
MMD2_k127_2180272_3 Putative zinc-finger - - - 0.0000000000000001917 90.0
MMD2_k127_2180272_4 PFAM copper resistance protein CopC K07156 - - 0.000001665 54.0
MMD2_k127_2185080_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 339.0
MMD2_k127_2185080_1 Glycosyltransferase like family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 299.0
MMD2_k127_2185080_2 Male sterility protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002801 277.0
MMD2_k127_2185080_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000004353 59.0
MMD2_k127_220216_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.357e-234 736.0
MMD2_k127_220216_1 Sigma-54 interaction domain - - - 5.015e-213 676.0
MMD2_k127_220216_10 2 iron, 2 sulfur cluster binding K01465,K02823,K05784,K17828 - 1.3.1.14,3.5.2.3 0.0000000000000000000000000000000000000000000000000000002632 202.0
MMD2_k127_220216_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000006132 198.0
MMD2_k127_220216_12 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000005736 181.0
MMD2_k127_220216_13 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000000000000000005591 160.0
MMD2_k127_220216_14 Transcriptional regulator - - - 0.000000000000000000000000000000000000003653 150.0
MMD2_k127_220216_15 Sulfurtransferase TusA - - - 0.0000000000000000000000118 105.0
MMD2_k127_220216_16 Tetratricopeptide repeat - - - 0.000000000001244 76.0
MMD2_k127_220216_17 4Fe-4S binding domain - - - 0.00000002458 59.0
MMD2_k127_220216_2 ribonuclease Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 464.0
MMD2_k127_220216_3 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 425.0
MMD2_k127_220216_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 379.0
MMD2_k127_220216_5 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 334.0
MMD2_k127_220216_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000004513 237.0
MMD2_k127_220216_7 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000000000000000008706 227.0
MMD2_k127_220216_8 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000003333 241.0
MMD2_k127_220216_9 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000001531 199.0
MMD2_k127_2213826_0 PFAM magnesium chelatase ChlI subunit K07391 - - 3.898e-209 662.0
MMD2_k127_2213826_1 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008709 484.0
MMD2_k127_2213826_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002836 396.0
MMD2_k127_2213826_4 Regulatory protein, FmdB family - - - 0.000000000000000003016 86.0
MMD2_k127_2244664_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 506.0
MMD2_k127_2244664_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 343.0
MMD2_k127_2244664_2 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000001129 216.0
MMD2_k127_2244664_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000006026 79.0
MMD2_k127_2312388_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009873 535.0
MMD2_k127_2312388_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 427.0
MMD2_k127_2312388_2 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000001001 132.0
MMD2_k127_2312388_3 S1 domain K00243 - - 0.00000000000000001311 83.0
MMD2_k127_2312388_4 Type II/IV secretion system protein K02669 - - 0.000000000146 62.0
MMD2_k127_2312388_5 - - - - 0.00004878 52.0
MMD2_k127_2327206_0 Belongs to the GPI family K01810 - 5.3.1.9 2.272e-201 634.0
MMD2_k127_2327206_1 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 430.0
MMD2_k127_2327206_2 NAD(P)H dehydrogenase (quinone) activity K03809 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0055114 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 331.0
MMD2_k127_2327206_3 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000008044 126.0
MMD2_k127_2327206_4 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533,K17686 - 3.6.3.4,3.6.3.54 0.0001609 47.0
MMD2_k127_2329282_0 polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000003908 211.0
MMD2_k127_2329282_1 Glycosyl transferase, family 2 K00721,K07011,K20444 - 2.4.1.83 0.00000000000000000000000000000000000000009946 163.0
MMD2_k127_2362711_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 6.384e-291 902.0
MMD2_k127_2362711_1 Dehydratase family K01687 - 4.2.1.9 5.298e-260 811.0
MMD2_k127_2362711_10 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007961 245.0
MMD2_k127_2362711_11 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.000000000000000000000000000000000000000000000000000000000207 207.0
MMD2_k127_2362711_12 Protein of unknown function (DUF465) K09794 - - 0.00000000000000002227 83.0
MMD2_k127_2362711_2 GTP-binding GTPase Middle Region K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 603.0
MMD2_k127_2362711_3 PFAM Radical SAM domain protein K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 586.0
MMD2_k127_2362711_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 454.0
MMD2_k127_2362711_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 419.0
MMD2_k127_2362711_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006291 341.0
MMD2_k127_2362711_7 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 331.0
MMD2_k127_2362711_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004542 269.0
MMD2_k127_2362711_9 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001433 256.0
MMD2_k127_2370060_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 1.383e-215 676.0
MMD2_k127_2370060_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.096e-214 672.0
MMD2_k127_2370060_10 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000001071 194.0
MMD2_k127_2370060_11 heat shock protein binding - - - 0.00000000000000000000000000000000001602 146.0
MMD2_k127_2370060_12 redox protein regulator of disulfide bond formation K07397 - - 0.00000000000000000000000003684 113.0
MMD2_k127_2370060_13 Heat shock protein DnaJ domain protein - - - 0.00000000167 69.0
MMD2_k127_2370060_2 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 524.0
MMD2_k127_2370060_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 398.0
MMD2_k127_2370060_4 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007901 398.0
MMD2_k127_2370060_5 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 357.0
MMD2_k127_2370060_6 Polyprenyl synthetase K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008429 335.0
MMD2_k127_2370060_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000001371 244.0
MMD2_k127_2370060_8 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000004988 242.0
MMD2_k127_2370060_9 ferrous iron binding K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000000003944 209.0
MMD2_k127_2376009_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 543.0
MMD2_k127_2376009_1 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 488.0
MMD2_k127_2376009_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004366 318.0
MMD2_k127_2376009_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003017 309.0
MMD2_k127_2376009_4 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 303.0
MMD2_k127_2376009_5 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004786 282.0
MMD2_k127_2376009_6 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000002347 138.0
MMD2_k127_2376009_7 PFAM EAL domain - - - 0.000000000000000000000001742 121.0
MMD2_k127_2376009_8 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000003152 97.0
MMD2_k127_2380215_0 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000008161 221.0
MMD2_k127_2380215_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000003356 184.0
MMD2_k127_2380215_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000008838 179.0
MMD2_k127_2380215_3 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000004287 135.0
MMD2_k127_238565_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001507 284.0
MMD2_k127_238565_1 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004346 275.0
MMD2_k127_238565_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000166 155.0
MMD2_k127_238565_3 Catalyzes the reversible hydration of fumarate to (S)- malate K01676,K03780 - 4.2.1.2,4.2.1.32 0.000000000000000000000000000005322 124.0
MMD2_k127_238565_4 Rhodanese Homology Domain - - - 0.00001109 55.0
MMD2_k127_2402717_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 376.0
MMD2_k127_2402717_1 Glycosyltransferase family 9 (heptosyltransferase) K02841,K02843 - - 0.000000000000000000000000000000000000005851 150.0
MMD2_k127_2412682_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.0 1127.0
MMD2_k127_2412682_1 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system K01547 - 3.6.3.12 0.0 1028.0
MMD2_k127_2412682_2 Osmosensitive K+ channel His kinase sensor domain K07646 - 2.7.13.3 1.033e-316 993.0
MMD2_k127_2412682_3 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane K01546 - 3.6.3.12 4.469e-217 682.0
MMD2_k127_2412682_4 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 328.0
MMD2_k127_2412682_5 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004037 299.0
MMD2_k127_2412682_6 Histidine kinase K07642,K18143 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002373 268.0
MMD2_k127_2412682_7 Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex K01548 - 3.6.3.12 0.00000000000000000000000000000000000000000000000000000000000000000001721 238.0
MMD2_k127_2412682_8 - - - - 0.0000000008023 65.0
MMD2_k127_2412682_9 Universal stress protein family - - - 0.0000001829 62.0
MMD2_k127_2424996_0 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 359.0
MMD2_k127_2424996_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 303.0
MMD2_k127_2424996_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000002458 205.0
MMD2_k127_2424996_3 MGS-like domain - - - 0.00000000000000000000000000000000000000000000000003645 187.0
MMD2_k127_2424996_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000001552 180.0
MMD2_k127_2424996_5 PFAM Uncharacterised protein family (UPF0153) - - - 0.000000000000000000000000000000000000000009911 163.0
MMD2_k127_2424996_6 Histidine kinase - - - 0.000000000000000000000000000000000000002267 152.0
MMD2_k127_2424996_7 - - - - 0.00000000000000004044 88.0
MMD2_k127_2433815_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 5.282e-200 638.0
MMD2_k127_2433815_1 Glu/Leu/Phe/Val dehydrogenase, dimerisation domain K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 458.0
MMD2_k127_2433815_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006154 330.0
MMD2_k127_2433815_3 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000001766 180.0
MMD2_k127_2433815_4 Male sterility protein - - - 0.000000000000000000000002141 113.0
MMD2_k127_2433815_5 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000004829 69.0
MMD2_k127_2442502_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 550.0
MMD2_k127_2442502_1 Pfam:Arch_ATPase - - - 0.000000000000009866 75.0
MMD2_k127_2442502_2 Histidine kinase A domain protein - - - 0.000000000001807 73.0
MMD2_k127_2442502_4 stage II sporulation protein E K07315 - 3.1.3.3 0.00000001102 62.0
MMD2_k127_2446322_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.175e-195 623.0
MMD2_k127_2446322_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 509.0
MMD2_k127_2446322_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 480.0
MMD2_k127_2446322_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003252 418.0
MMD2_k127_2446322_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008403 308.0
MMD2_k127_2446322_5 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 294.0
MMD2_k127_2446322_6 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000001919 227.0
MMD2_k127_2446322_7 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000003437 190.0
MMD2_k127_2446322_8 bacterial (prokaryotic) histone like domain K05788 - - 0.00000000000000000000003438 101.0
MMD2_k127_2447494_0 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000348 367.0
MMD2_k127_2447494_1 Domain of Unknown Function with PDB structure (DUF3857) - - - 0.0000000000000000000000000000000000000000000000000000000004048 226.0
MMD2_k127_2447494_3 PEGA domain - - - 0.0000002198 55.0
MMD2_k127_2447494_4 PFAM type IV pilus assembly PilZ - - - 0.00002102 54.0
MMD2_k127_2457418_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.991e-318 981.0
MMD2_k127_2457418_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 491.0
MMD2_k127_2457418_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 358.0
MMD2_k127_2457418_3 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000000000005865 160.0
MMD2_k127_2457418_4 Nucleotide pyrophosphohydrolase - - - 0.00000000000000000000000000000001096 130.0
MMD2_k127_2457418_5 SpoIIAA-like - - - 0.000000000000000000000556 100.0
MMD2_k127_2457418_6 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000003849 93.0
MMD2_k127_2457418_7 SpoVT / AbrB like domain K07172 - - 0.0000000000000001257 82.0
MMD2_k127_2457418_8 - - - - 0.00000000001512 67.0
MMD2_k127_245818_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 1.383e-269 841.0
MMD2_k127_245818_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.00000000000000000000000000000005466 126.0
MMD2_k127_245818_2 Ferredoxin K17992 - 1.12.1.3 0.00000000001125 66.0
MMD2_k127_2463101_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 5.747e-218 682.0
MMD2_k127_2463101_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 481.0
MMD2_k127_2463101_2 Uncharacterised MFS-type transporter YbfB - - - 0.000000000000000000000000000000000000000000000000000000000238 207.0
MMD2_k127_2463101_3 RNA recognition motif - - - 0.0000000000000000000000004708 109.0
MMD2_k127_2463101_4 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000001901 72.0
MMD2_k127_2467458_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 317.0
MMD2_k127_2467458_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000294 275.0
MMD2_k127_2467458_2 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 262.0
MMD2_k127_2467458_3 Putative MetA-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 237.0
MMD2_k127_2467458_4 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000005961 180.0
MMD2_k127_2467458_5 PFAM Cobalt uptake substrate-specific transmembrane region K02007 - - 0.00000000000000000000000000000000001011 140.0
MMD2_k127_2467666_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 404.0
MMD2_k127_2467666_1 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 393.0
MMD2_k127_2468335_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1067.0
MMD2_k127_2468335_1 fatty acid beta-oxidation using acyl-CoA dehydrogenase K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 494.0
MMD2_k127_2468335_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 437.0
MMD2_k127_2468335_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007792 303.0
MMD2_k127_2468335_4 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000005368 164.0
MMD2_k127_2471387_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 595.0
MMD2_k127_2471387_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000008392 221.0
MMD2_k127_2471387_2 Thioesterase K18700 - 3.1.2.29 0.000000000000000000000000000000000000000000000000000000000004157 211.0
MMD2_k127_2471387_3 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000000000000000000002705 186.0
MMD2_k127_2471387_4 Protein of unknown function (DUF4019) - - - 0.000000000000000000000000000000000000002474 151.0
MMD2_k127_2471387_5 Diguanylate cyclase - - - 0.000000000000000000000000000000001866 140.0
MMD2_k127_2502178_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 349.0
MMD2_k127_2502178_1 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 320.0
MMD2_k127_2502178_2 Peptide methionine sulfoxide reductase K07304 - 1.8.4.11 0.0000000000000000000000000001643 118.0
MMD2_k127_2502178_3 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000604 105.0
MMD2_k127_2536127_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 364.0
MMD2_k127_2547114_0 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000002819 159.0
MMD2_k127_2547114_1 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000003192 139.0
MMD2_k127_2547114_2 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000002149 138.0
MMD2_k127_2547114_3 HEAT repeat - - - 0.0000000000000000000000001792 119.0
MMD2_k127_2547114_4 Chemotaxis sensory transducer - - - 0.0000402 53.0
MMD2_k127_2574393_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003334 446.0
MMD2_k127_2574393_1 PFAM inositol monophosphatase K01082 - 3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 299.0
MMD2_k127_2574393_2 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007913 290.0
MMD2_k127_2574393_3 Adenylylsulphate kinase K00955 - 2.7.1.25,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000005171 217.0
MMD2_k127_2574393_4 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000009513 175.0
MMD2_k127_2574393_5 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000000000000000009088 135.0
MMD2_k127_2576300_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 439.0
MMD2_k127_2576300_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases - - - 0.0000000003156 66.0
MMD2_k127_2599536_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 343.0
MMD2_k127_2599536_1 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 333.0
MMD2_k127_2599536_2 - - - - 0.00000000000000000000000000000000000000000000000000000000003769 218.0
MMD2_k127_2599536_3 Predicted membrane protein (DUF2318) - - - 0.000000000001826 74.0
MMD2_k127_2599536_4 Uncharacterized integral membrane protein (DUF2301) - - - 0.00000003062 66.0
MMD2_k127_2615201_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 520.0
MMD2_k127_2615201_1 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 375.0
MMD2_k127_2615201_2 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000038 231.0
MMD2_k127_2615201_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000007331 121.0
MMD2_k127_2615330_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 456.0
MMD2_k127_2615330_1 ABC-type transport system involved in lipoprotein release permease component K02004,K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0089705,GO:0098796,GO:0098797,GO:1990778 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004612 381.0
MMD2_k127_2615330_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
MMD2_k127_2615330_3 lipoprotein involved in nitrous oxide reduction - - - 0.00000000000000000000000000000000000000001465 160.0
MMD2_k127_2615330_4 Predicted membrane protein (DUF2318) - - - 0.0000000000000000000000001919 111.0
MMD2_k127_2615330_5 - - - - 0.00000000000000000000007406 101.0
MMD2_k127_2615330_6 Cytochrome c554 and c-prime - - - 0.000005682 48.0
MMD2_k127_2616598_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005179 506.0
MMD2_k127_2616598_1 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000000000000002005 204.0
MMD2_k127_2616598_2 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000132 194.0
MMD2_k127_2617725_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.273e-196 619.0
MMD2_k127_2617725_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 607.0
MMD2_k127_2617725_10 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000000000000000000000000000000005134 210.0
MMD2_k127_2617725_11 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000005378 198.0
MMD2_k127_2617725_12 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000002979 142.0
MMD2_k127_2617725_13 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000001024 94.0
MMD2_k127_2617725_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 GO:0003674,GO:0005488,GO:0006417,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044087,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:0090069,GO:0090071,GO:2000112,GO:2000113 - 0.0000000002477 63.0
MMD2_k127_2617725_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 501.0
MMD2_k127_2617725_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 487.0
MMD2_k127_2617725_4 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006494 439.0
MMD2_k127_2617725_5 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 418.0
MMD2_k127_2617725_6 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 364.0
MMD2_k127_2617725_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 341.0
MMD2_k127_2617725_8 Peptidase M16 domain protein K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 298.0
MMD2_k127_2617725_9 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000002064 229.0
MMD2_k127_2617747_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 1.166e-277 868.0
MMD2_k127_2617747_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 545.0
MMD2_k127_2617747_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000001501 270.0
MMD2_k127_2617747_3 glycolate biosynthetic process K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000004701 226.0
MMD2_k127_2617747_4 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000001334 181.0
MMD2_k127_2617747_5 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.00000000000000000000000000000000000001486 152.0
MMD2_k127_2617747_6 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000009596 107.0
MMD2_k127_2634129_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000007953 123.0
MMD2_k127_2634129_1 amine dehydrogenase activity - - - 0.00000000000001368 78.0
MMD2_k127_264071_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 419.0
MMD2_k127_264071_1 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000001792 197.0
MMD2_k127_264071_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.000000003 65.0
MMD2_k127_264071_3 PFAM tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000002439 51.0
MMD2_k127_2676708_0 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005948 326.0
MMD2_k127_2676708_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 278.0
MMD2_k127_2676708_2 - - - - 0.0000000000000000000000000000000000000000001411 165.0
MMD2_k127_2698578_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 428.0
MMD2_k127_2698578_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000001676 154.0
MMD2_k127_2698578_2 - - - - 0.00001817 50.0
MMD2_k127_2698578_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00004098 46.0
MMD2_k127_2730209_0 PFAM Polysulphide reductase, NrfD K00185 - - 6.778e-224 705.0
MMD2_k127_2730209_1 lyase activity - - - 0.0000000000000000002131 95.0
MMD2_k127_2730534_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 450.0
MMD2_k127_2730534_1 PFAM Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000005584 145.0
MMD2_k127_2732708_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002221 520.0
MMD2_k127_2732708_1 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009116 437.0
MMD2_k127_2732708_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000003027 118.0
MMD2_k127_2772745_0 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009343 601.0
MMD2_k127_2772745_1 COG0463 Glycosyltransferases involved in cell wall biogenesis K13693 - 2.4.1.266 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 373.0
MMD2_k127_2772745_2 transmembrane transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004882 258.0
MMD2_k127_2772745_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0
MMD2_k127_2772745_4 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000004055 153.0
MMD2_k127_2772745_5 - - - - 0.0000000002624 66.0
MMD2_k127_2772745_6 PFAM Transposase IS200 like - - - 0.00000003371 58.0
MMD2_k127_278080_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.222e-273 854.0
MMD2_k127_278080_1 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 328.0
MMD2_k127_278080_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides - - - 0.0000000000000000000000000000000000000000000000001031 181.0
MMD2_k127_278080_3 glycolate transport K14393 - - 0.000000001356 59.0
MMD2_k127_2812705_0 GAF domain K02584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 521.0
MMD2_k127_2812705_1 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000003686 205.0
MMD2_k127_2816909_0 4Fe-4S double cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008507 235.0
MMD2_k127_2816909_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000004863 217.0
MMD2_k127_2816909_2 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000002811 167.0
MMD2_k127_2816909_3 Yhs domain-containing protein - - - 0.0000000000000000000000000000000000000000002114 163.0
MMD2_k127_2816909_4 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000001021 116.0
MMD2_k127_2816909_5 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000009772 97.0
MMD2_k127_2816909_6 Pentapeptide repeat protein - - - 0.00000000000001473 82.0
MMD2_k127_2816909_7 DsrE/DsrF-like family K07092 - - 0.0001392 50.0
MMD2_k127_2837513_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1042.0
MMD2_k127_2837513_1 PFAM lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000004544 261.0
MMD2_k127_2837513_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000177 234.0
MMD2_k127_2838624_0 ATPase BadF BadG BcrA BcrD type - - - 1.36e-277 874.0
MMD2_k127_2838624_1 Prokaryotic N-terminal methylation motif K02650,K02682 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000002746 53.0
MMD2_k127_287700_0 transferase activity, transferring glycosyl groups K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 323.0
MMD2_k127_287700_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000002739 183.0
MMD2_k127_287700_2 Glycosyltransferase like family 2 K07011,K20444 - - 0.00000000000000000000000006239 120.0
MMD2_k127_287700_3 biosynthesis glycosyltransferase - - - 0.0000000000000000000000001207 109.0
MMD2_k127_287700_4 DUF based on E. rectale Gene description (DUF3880) K06320 - - 0.00000000001714 68.0
MMD2_k127_287700_5 COGs COG3307 Lipid A core - O-antigen ligase - - - 0.0000261 56.0
MMD2_k127_2896413_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 355.0
MMD2_k127_2902840_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.291e-221 693.0
MMD2_k127_2902840_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000004748 238.0
MMD2_k127_2902840_2 translation initiation inhibitor, yjgF family - - - 0.00000000000000002917 83.0
MMD2_k127_2919010_0 PFAM peptidase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 413.0
MMD2_k127_2919010_1 cheY-homologous receiver domain K11522 - - 0.000000002738 68.0
MMD2_k127_2935223_0 PFAM S-adenosylmethionine synthetase (MAT) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005824 547.0
MMD2_k127_2935223_1 DsrC like protein K11179 - - 0.00000000000000000000000000003888 119.0
MMD2_k127_2935223_2 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000001639 117.0
MMD2_k127_2935223_3 electron transfer activity K05337,K17247 - - 0.00000000000000000000000003997 108.0
MMD2_k127_2949709_0 Uroporphyrinogen decarboxylase (URO-D) K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 438.0
MMD2_k127_2949709_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000002617 186.0
MMD2_k127_2949709_2 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000001653 153.0
MMD2_k127_2960730_0 Response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 546.0
MMD2_k127_2960730_1 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000000005906 221.0
MMD2_k127_2960730_2 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.0000000000000000000000000000000000000000002255 160.0
MMD2_k127_2960730_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000003905 106.0
MMD2_k127_3040252_0 FtsX-like permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 324.0
MMD2_k127_3040252_1 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 317.0
MMD2_k127_3040252_2 - - - - 0.0000000000000000000000000000000000000000000097 166.0
MMD2_k127_3050967_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 607.0
MMD2_k127_3050967_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 350.0
MMD2_k127_3050967_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 296.0
MMD2_k127_3050967_3 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000004585 187.0
MMD2_k127_3081704_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 489.0
MMD2_k127_3081704_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
MMD2_k127_309004_0 galactose-1-phosphate uridylyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006339 267.0
MMD2_k127_309004_1 SMART Signal transduction response regulator, receiver domain - - - 0.0000000000000000000000000000000000000000000006555 177.0
MMD2_k127_3143302_0 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 355.0
MMD2_k127_3143302_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000009837 241.0
MMD2_k127_3165106_0 alpha amylase, catalytic region - - - 1.146e-236 741.0
MMD2_k127_3165106_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 383.0
MMD2_k127_3165106_2 Glycogen debranching enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000008247 228.0
MMD2_k127_3169849_0 PFAM NADH Ubiquinone plastoquinone (complex I) K12141 - - 2.337e-195 620.0
MMD2_k127_3169849_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 408.0
MMD2_k127_3169849_10 - - - - 0.0000000000000008167 81.0
MMD2_k127_3169849_11 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000621 56.0
MMD2_k127_3169849_2 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 410.0
MMD2_k127_3169849_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 406.0
MMD2_k127_3169849_4 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 376.0
MMD2_k127_3169849_5 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 366.0
MMD2_k127_3169849_6 HycBCDEFG is part of the formate hydrogenlyase system which is involved in the cleaving of formate to dihydrogen and carbon dioxide K12138,K12139,K15829 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016020,GO:0033554,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 289.0
MMD2_k127_3169849_7 hydrogenase 4 membrane K12140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001331 245.0
MMD2_k127_3169849_8 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000001033 233.0
MMD2_k127_3169849_9 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000001468 149.0
MMD2_k127_3180410_0 Biotin and Thiamin Synthesis associated K03150 - 4.1.99.19 1.392e-249 776.0
MMD2_k127_3180410_1 Iron hydrogenase small subunit K00336,K18332 - 1.12.1.3,1.6.5.3 5.602e-229 711.0
MMD2_k127_3180410_2 Elongator protein 3, MiaB family, Radical SAM K01012 - 2.8.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 492.0
MMD2_k127_3180410_3 Fumarase C C-terminus K01744 - 4.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004031 249.0
MMD2_k127_3184668_0 Domain of unknown function (DUF362) K07138 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 366.0
MMD2_k127_3184668_1 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009604 353.0
MMD2_k127_3184668_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000005465 132.0
MMD2_k127_3184668_5 VanZ like family - - - 0.0000002806 56.0
MMD2_k127_3184669_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 9.799e-209 657.0
MMD2_k127_3184669_1 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 456.0
MMD2_k127_3184669_10 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001719 235.0
MMD2_k127_3184669_11 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000003641 215.0
MMD2_k127_3184669_12 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000135 216.0
MMD2_k127_3184669_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000007829 205.0
MMD2_k127_3184669_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001061 202.0
MMD2_k127_3184669_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000751 200.0
MMD2_k127_3184669_16 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000002774 184.0
MMD2_k127_3184669_17 Binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000001132 183.0
MMD2_k127_3184669_18 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000005932 169.0
MMD2_k127_3184669_19 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000009197 168.0
MMD2_k127_3184669_2 rRNA binding K02886 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 374.0
MMD2_k127_3184669_20 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000005019 156.0
MMD2_k127_3184669_21 Ribosomal L18 of archaea, bacteria, mitoch. and chloroplast K02881 - - 0.000000000000000000000000000000000000003399 149.0
MMD2_k127_3184669_22 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000002804 139.0
MMD2_k127_3184669_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000007609 136.0
MMD2_k127_3184669_24 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.0000000000000000000000000000000006399 131.0
MMD2_k127_3184669_25 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000004675 110.0
MMD2_k127_3184669_26 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000073 109.0
MMD2_k127_3184669_27 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000009355 106.0
MMD2_k127_3184669_28 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000004921 81.0
MMD2_k127_3184669_29 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000952 76.0
MMD2_k127_3184669_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 356.0
MMD2_k127_3184669_30 Ribosomal protein L36 K02919 - - 0.0000000000001547 70.0
MMD2_k127_3184669_31 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000005293 64.0
MMD2_k127_3184669_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 330.0
MMD2_k127_3184669_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007912 326.0
MMD2_k127_3184669_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 285.0
MMD2_k127_3184669_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002864 280.0
MMD2_k127_3184669_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005554 278.0
MMD2_k127_3184669_9 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001075 235.0
MMD2_k127_3201023_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 602.0
MMD2_k127_3201023_1 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000007835 264.0
MMD2_k127_3201023_2 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004924 251.0
MMD2_k127_3202160_0 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 484.0
MMD2_k127_3202160_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000009224 158.0
MMD2_k127_3202160_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000005728 121.0
MMD2_k127_3202160_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000002558 83.0
MMD2_k127_3204272_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006073 287.0
MMD2_k127_3204272_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000772 173.0
MMD2_k127_3204272_2 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000001964 74.0
MMD2_k127_3205846_0 Molecular chaperone. Has ATPase activity K04079 - - 7.654e-273 852.0
MMD2_k127_3205846_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 415.0
MMD2_k127_3205846_2 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 376.0
MMD2_k127_3205846_3 Cold shock protein K03704 - - 0.0000000000000000000000009662 106.0
MMD2_k127_3205846_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000001229 105.0
MMD2_k127_3222765_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 498.0
MMD2_k127_3222765_1 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000839 109.0
MMD2_k127_3237886_0 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000001989 102.0
MMD2_k127_3237886_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000001058 75.0
MMD2_k127_3237886_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0031123,GO:0031404,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000628 68.0
MMD2_k127_3237886_3 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000001807 57.0
MMD2_k127_3251942_0 Sigma-54 interaction domain K02481,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 436.0
MMD2_k127_3251942_1 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007359 255.0
MMD2_k127_3251942_2 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000174 233.0
MMD2_k127_3251942_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000005192 253.0
MMD2_k127_3251942_4 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000005918 226.0
MMD2_k127_3251942_5 Belongs to the Fur family K03711,K09825 - - 0.0000000000000000000000000000000000000000000000002121 179.0
MMD2_k127_3251942_6 - - - - 0.000000000000000000000000000000000000000009487 159.0
MMD2_k127_3251942_7 - - - - 0.0005221 45.0
MMD2_k127_3254348_0 Elongation factor G, domain IV K02355 - - 8.374e-289 899.0
MMD2_k127_3254348_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 527.0
MMD2_k127_3254348_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 341.0
MMD2_k127_3254348_3 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000004646 226.0
MMD2_k127_3254348_4 Membrane - - - 0.00000000000000000000000726 110.0
MMD2_k127_3265288_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 512.0
MMD2_k127_3265288_1 Transcription termination factor nusG - - - 0.00000000000000000000000000000000000000000008571 164.0
MMD2_k127_3265288_2 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000004053 128.0
MMD2_k127_3265288_3 Bacterial sugar transferase - - - 0.0000000000000000000001128 101.0
MMD2_k127_32804_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 6.669e-257 802.0
MMD2_k127_32804_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000574 348.0
MMD2_k127_32804_2 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 296.0
MMD2_k127_32804_3 imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000198 254.0
MMD2_k127_32804_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009301 246.0
MMD2_k127_32804_5 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000892 209.0
MMD2_k127_3286954_0 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 497.0
MMD2_k127_3286954_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 378.0
MMD2_k127_3296491_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008133 604.0
MMD2_k127_3296491_1 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 467.0
MMD2_k127_3296491_2 Cellulose synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 428.0
MMD2_k127_3296491_3 Cellulose biosynthesis protein BcsG - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000199 286.0
MMD2_k127_3296491_5 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000000549 65.0
MMD2_k127_3313726_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 385.0
MMD2_k127_3313726_1 ATP cone domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004461 232.0
MMD2_k127_3313726_2 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000003427 192.0
MMD2_k127_3313726_3 Protein of unknown function (DUF3365) - - - 0.0000000000000000000000000000000000001516 146.0
MMD2_k127_3375845_0 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 347.0
MMD2_k127_3375845_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000002372 232.0
MMD2_k127_3375845_2 Rubrerythrin - - - 0.000000000000000000000000000000000000001261 151.0
MMD2_k127_3396168_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01840,K15778 - 5.4.2.2,5.4.2.8 2.217e-218 685.0
MMD2_k127_3396168_1 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 608.0
MMD2_k127_3396168_2 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 313.0
MMD2_k127_3396168_4 PBS lyase HEAT-like repeat - - - 0.00003679 52.0
MMD2_k127_3408363_0 TRCF K03723 - - 1.43e-229 747.0
MMD2_k127_3408363_1 PAS domain K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 460.0
MMD2_k127_3408363_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000008754 195.0
MMD2_k127_3408363_3 - - - - 0.000000000006926 68.0
MMD2_k127_3408363_4 NUDIX domain - - - 0.000002467 50.0
MMD2_k127_3438376_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 313.0
MMD2_k127_3438376_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004763 255.0
MMD2_k127_3438376_2 CGGC - - - 0.00000000000000000000000000000000000000000000000000009515 189.0
MMD2_k127_3438376_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000003759 190.0
MMD2_k127_3438376_4 Small glutamine-rich tetratricopeptide K16365 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006457,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0007029,GO:0008022,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009893,GO:0009894,GO:0009895,GO:0009896,GO:0009987,GO:0010033,GO:0010243,GO:0010256,GO:0010498,GO:0010604,GO:0010605,GO:0016020,GO:0016043,GO:0019222,GO:0019538,GO:0019941,GO:0030162,GO:0030163,GO:0030433,GO:0030544,GO:0031072,GO:0031323,GO:0031324,GO:0031325,GO:0031329,GO:0031330,GO:0031331,GO:0031333,GO:0032268,GO:0032269,GO:0032270,GO:0032434,GO:0032435,GO:0032436,GO:0032459,GO:0032460,GO:0033036,GO:0033365,GO:0033554,GO:0034613,GO:0034976,GO:0036503,GO:0042176,GO:0042177,GO:0042221,GO:0042802,GO:0042803,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043254,GO:0043621,GO:0043632,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0045048,GO:0045184,GO:0045732,GO:0045861,GO:0045862,GO:0046982,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048585,GO:0050789,GO:0050794,GO:0050896,GO:0051087,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051205,GO:0051234,GO:0051246,GO:0051247,GO:0051248,GO:0051603,GO:0051641,GO:0051716,GO:0060255,GO:0061024,GO:0061136,GO:0065007,GO:0070727,GO:0071704,GO:0071816,GO:0071840,GO:0072657,GO:0080090,GO:0080134,GO:0080135,GO:0090150,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901799,GO:1901800,GO:1903050,GO:1903051,GO:1903052,GO:1903069,GO:1903070,GO:1903071,GO:1903332,GO:1903334,GO:1903362,GO:1903363,GO:1903364,GO:1903573,GO:1903644,GO:1903646,GO:1904288,GO:1904292,GO:1904293,GO:1904294,GO:1905897,GO:1905898,GO:2000058,GO:2000059,GO:2000060 - 0.000000009133 64.0
MMD2_k127_3438376_5 Phosphoesterase family - - - 0.00000006234 64.0
MMD2_k127_344271_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 303.0
MMD2_k127_344271_1 Competence protein K02238 - - 0.000000000000000000000000000000000000000000000001049 194.0
MMD2_k127_3536623_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 316.0
MMD2_k127_3536623_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 317.0
MMD2_k127_3536623_10 proteolysis K03665 - - 0.00000000000000000000000000000004947 130.0
MMD2_k127_3536623_11 Belongs to the glycosyl hydrolase 43 family - - - 0.0000000000000000000000000000001038 132.0
MMD2_k127_3536623_12 Peptidase family M50 - - - 0.00000000000000005406 82.0
MMD2_k127_3536623_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000144 271.0
MMD2_k127_3536623_3 Belongs to the metallo-dependent hydrolases superfamily. NagA family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003924 260.0
MMD2_k127_3536623_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000004332 196.0
MMD2_k127_3536623_5 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000007686 173.0
MMD2_k127_3536623_6 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000001107 164.0
MMD2_k127_3536623_7 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000171 154.0
MMD2_k127_3536623_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K03832 - - 0.0000000000000000000000000000000000002163 152.0
MMD2_k127_3536623_9 Universal stress protein family - - - 0.0000000000000000000000000000000000009318 145.0
MMD2_k127_3542122_0 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 501.0
MMD2_k127_3542122_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000009583 173.0
MMD2_k127_3548023_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 2.699e-296 924.0
MMD2_k127_3548023_1 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 327.0
MMD2_k127_3548023_2 Phospholipid methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000001024 200.0
MMD2_k127_3562228_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 587.0
MMD2_k127_3562228_1 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006456 280.0
MMD2_k127_3600146_0 Telomere recombination K04656 - - 5.262e-231 738.0
MMD2_k127_3600146_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 479.0
MMD2_k127_3600146_10 nickel cation binding K04651,K19640 - - 0.00000000000000000000000000002521 121.0
MMD2_k127_3600146_11 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000502 120.0
MMD2_k127_3600146_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000001032 107.0
MMD2_k127_3600146_13 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000001213 102.0
MMD2_k127_3600146_14 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000001212 101.0
MMD2_k127_3600146_15 - - - - 0.000000000000004571 80.0
MMD2_k127_3600146_16 peptidylprolyl isomerase K03769,K07533 - 5.2.1.8 0.000000003682 67.0
MMD2_k127_3600146_2 Hydrogenase formation hypA family K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 451.0
MMD2_k127_3600146_3 AIR synthase related protein, C-terminal domain K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 357.0
MMD2_k127_3600146_4 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 315.0
MMD2_k127_3600146_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 314.0
MMD2_k127_3600146_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 308.0
MMD2_k127_3600146_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000009939 198.0
MMD2_k127_3600146_8 PFAM CBS domain - - - 0.00000000000000000000000000000000000002387 148.0
MMD2_k127_3600146_9 Smr domain - - - 0.000000000000000000000000000001723 129.0
MMD2_k127_3627606_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 2.204e-226 719.0
MMD2_k127_3627606_1 FR47-like protein - - - 0.0000000000000000533 83.0
MMD2_k127_3627606_2 - - - - 0.00000000000001304 79.0
MMD2_k127_3627606_3 Nitrate reductase gamma subunit - - - 0.0001 52.0
MMD2_k127_3634592_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008461 579.0
MMD2_k127_3634592_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 460.0
MMD2_k127_3634592_2 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 408.0
MMD2_k127_3634592_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002668 280.0
MMD2_k127_3634592_4 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000001335 168.0
MMD2_k127_3634592_5 DSBA-like thioredoxin domain - - - 0.000001145 51.0
MMD2_k127_3634682_0 ABC transporter K06158 - - 5.259e-238 750.0
MMD2_k127_3685503_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008629 505.0
MMD2_k127_3685503_1 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 424.0
MMD2_k127_3685503_2 shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000000003891 173.0
MMD2_k127_3685503_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000001446 97.0
MMD2_k127_3685503_4 TIGRFAM rod shape-determining protein MreD K03571 - - 0.0009359 48.0
MMD2_k127_3714130_0 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 405.0
MMD2_k127_3714130_1 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 321.0
MMD2_k127_3715731_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000000003465 242.0
MMD2_k127_3715731_1 Protein of unknown function, DUF480 K09915 - - 0.00000000000000000000000000000000000000000000000000000000002378 213.0
MMD2_k127_3715731_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000002552 128.0
MMD2_k127_3715731_3 - - - - 0.000000003913 58.0
MMD2_k127_3715731_4 ACT domain protein - - - 0.0001383 51.0
MMD2_k127_3722735_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 2.834e-202 643.0
MMD2_k127_3722735_1 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000003492 245.0
MMD2_k127_3736602_0 DNA photolyase K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008065 585.0
MMD2_k127_3736602_1 PFAM Alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 466.0
MMD2_k127_3736602_2 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.000000000000000000000000000000000000000003534 165.0
MMD2_k127_3736602_3 ferredoxin-thioredoxin reductase activity - - - 0.000000000000000000000000000000000000000008703 156.0
MMD2_k127_3736602_4 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000003559 108.0
MMD2_k127_3736602_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.000000000000000001237 87.0
MMD2_k127_3750006_0 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 330.0
MMD2_k127_3750006_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 316.0
MMD2_k127_3750006_2 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000000000000000305 236.0
MMD2_k127_3750006_3 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000602 191.0
MMD2_k127_3750006_4 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000001224 194.0
MMD2_k127_3750006_5 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000001594 184.0
MMD2_k127_3750006_6 - - - - 0.00000005498 61.0
MMD2_k127_3750006_7 protein transport across the cell outer membrane K02246,K02457,K02459,K02672,K08084 - - 0.0000003634 59.0
MMD2_k127_3750006_8 type IV pilus modification protein PilV K02458,K02671 - - 0.0003381 48.0
MMD2_k127_3755900_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 433.0
MMD2_k127_3755900_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008632 341.0
MMD2_k127_3755900_2 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000001571 172.0
MMD2_k127_3755900_3 Thioesterase-like superfamily K07107 - - 0.00000000000001639 74.0
MMD2_k127_3806225_0 Aconitase C-terminal domain K01681 - 4.2.1.3 4.272e-270 841.0
MMD2_k127_3806225_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 5.059e-257 798.0
MMD2_k127_3806225_2 also catalyzes the condensation of oxaloacetate with acetyl-CoA but with a lower specificity K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 574.0
MMD2_k127_3806225_3 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 441.0
MMD2_k127_3810461_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 445.0
MMD2_k127_3810461_1 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004104 271.0
MMD2_k127_3930845_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 1.135e-239 764.0
MMD2_k127_3930845_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 382.0
MMD2_k127_3930845_10 PFAM response regulator receiver K02483,K07658 - - 0.0000000000000000009509 93.0
MMD2_k127_3930845_2 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005529 335.0
MMD2_k127_3930845_3 Belongs to the pseudouridine synthase RluA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002334 256.0
MMD2_k127_3930845_4 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000001792 236.0
MMD2_k127_3930845_5 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000001022 211.0
MMD2_k127_3930845_6 Esterase PHB depolymerase K03932 - - 0.0000000000000000000000000000000000000000000000000001654 197.0
MMD2_k127_3930845_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.0000000000000000000000000000000000000000004642 164.0
MMD2_k127_3930845_8 NosL - - - 0.0000000000000000000000000000000000000000005462 169.0
MMD2_k127_3930845_9 NosL - - - 0.0000000000000000000000000000000000000002699 161.0
MMD2_k127_3931222_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1227.0
MMD2_k127_3931222_1 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.0000000000000000000000000000000000000001241 154.0
MMD2_k127_3931222_2 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K13640 GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000003547 137.0
MMD2_k127_3931222_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000006103 106.0
MMD2_k127_3931222_4 AMP binding K06149 - - 0.0000000036 62.0
MMD2_k127_3932063_0 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000003427 245.0
MMD2_k127_3932063_1 Protein export membrane protein K07003 - - 0.000000000000000000000000000000000000000000000000000005144 215.0
MMD2_k127_3932063_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000004698 168.0
MMD2_k127_3932063_3 - - - - 0.0000000000000000000000000000003611 126.0
MMD2_k127_3932063_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000003846 103.0
MMD2_k127_3932063_5 acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.000000000000000000002927 101.0
MMD2_k127_3932063_6 Cupin 2, conserved barrel domain protein - - - 0.00000000000000003433 86.0
MMD2_k127_3932063_7 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000008457 73.0
MMD2_k127_3932063_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000182 72.0
MMD2_k127_3972194_0 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008205 569.0
MMD2_k127_3972194_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003536 429.0
MMD2_k127_3972194_2 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000004732 176.0
MMD2_k127_3972194_3 nucleotide metabolic process - - - 0.00000000000000000000000000000000002653 143.0
MMD2_k127_3976691_0 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 400.0
MMD2_k127_3976691_1 COG2223 Nitrate nitrite transporter K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000179 274.0
MMD2_k127_3976691_2 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000001352 245.0
MMD2_k127_3976691_3 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000000000000000000003741 171.0
MMD2_k127_3976691_4 cyclic nucleotide-binding K10914 - - 0.000000000000000000000000002266 120.0
MMD2_k127_3976691_5 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000001533 113.0
MMD2_k127_3976691_6 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000000000000000000532 101.0
MMD2_k127_3976691_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000005846 100.0
MMD2_k127_3976691_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K14986 - 2.7.13.3 0.000000000000000001815 93.0
MMD2_k127_3976691_9 - - - - 0.0000004928 59.0
MMD2_k127_39797_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 324.0
MMD2_k127_39797_1 protein trimerization K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000002826 174.0
MMD2_k127_39797_2 PFAM Response regulator receiver domain K07658 - - 0.0000002574 57.0
MMD2_k127_3989777_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00362 - 1.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 335.0
MMD2_k127_3989777_1 Belongs to the Fur family K02076,K03711 GO:0000976,GO:0001067,GO:0001130,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0032993,GO:0043565,GO:0044212,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000002423 183.0
MMD2_k127_3989777_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000008506 92.0
MMD2_k127_4013893_0 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 332.0
MMD2_k127_4013893_1 PspA/IM30 family K03969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 304.0
MMD2_k127_4013893_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001346 243.0
MMD2_k127_4013893_3 phosphoribosyltransferases - - - 0.0000000000000000000000000000000000000000001742 162.0
MMD2_k127_4013893_4 glucosylceramidase activity - - - 0.000000000000000000000000000000000007294 139.0
MMD2_k127_4013893_5 - - - - 0.000000000000000000000003431 104.0
MMD2_k127_4013893_6 Bacterial protein of unknown function (DUF937) - - - 0.00000000000001231 82.0
MMD2_k127_4013893_7 TM2 domain - - - 0.000003682 55.0
MMD2_k127_4033734_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 312.0
MMD2_k127_4033734_1 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000004495 187.0
MMD2_k127_4033734_2 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000267 165.0
MMD2_k127_4033734_3 - - - - 0.000000000000000000000000000000000000001247 149.0
MMD2_k127_4033734_4 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000001042 120.0
MMD2_k127_403950_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.134e-223 702.0
MMD2_k127_403950_1 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 377.0
MMD2_k127_403950_2 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000001848 239.0
MMD2_k127_403950_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000000000000000000000000000000001028 190.0
MMD2_k127_403950_4 - - - - 0.000000000000000000000000000000000000000000000000001502 188.0
MMD2_k127_403950_5 CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000000005563 131.0
MMD2_k127_403950_6 Cytochrome c K08906,K12263 - - 0.00000000000000000001105 96.0
MMD2_k127_4051963_0 Carbohydrate phosphorylase K00688,K00691 - 2.4.1.1,2.4.1.8 8.5e-297 933.0
MMD2_k127_4058457_0 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000004006 260.0
MMD2_k127_4058457_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000017 191.0
MMD2_k127_4058457_10 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000001797 66.0
MMD2_k127_4058457_2 metalloendopeptidase activity K03799 - - 0.0000000000000000000000000000000000000000000000001069 197.0
MMD2_k127_4058457_3 LemA family K03744 - - 0.00000000000000000000000000000000000000000000002959 175.0
MMD2_k127_4058457_4 Protein of unknown function (DUF1255) K09913 - 2.4.2.1,2.4.2.2 0.0000000000000000000000000000000000000001138 154.0
MMD2_k127_4058457_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000001194 139.0
MMD2_k127_4058457_6 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000002938 141.0
MMD2_k127_4058457_7 Cold shock K03704 - - 0.0000000000000000000000001018 107.0
MMD2_k127_4058457_8 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000006879 100.0
MMD2_k127_4058457_9 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000008285 93.0
MMD2_k127_4059019_0 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 450.0
MMD2_k127_4059019_1 WYL domain K13573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002067 267.0
MMD2_k127_4059019_2 alanine aminotransferase K00814 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004021,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009507,GO:0009536,GO:0009628,GO:0009987,GO:0010035,GO:0010038,GO:0016054,GO:0016740,GO:0016769,GO:0017076,GO:0019481,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036293,GO:0042221,GO:0042851,GO:0042853,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046686,GO:0047635,GO:0050896,GO:0070482,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.2 0.0000001812 54.0
MMD2_k127_4065500_0 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 291.0
MMD2_k127_4065500_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002058 285.0
MMD2_k127_4065500_2 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000006131 195.0
MMD2_k127_4065500_3 Sulfatase - - - 0.0000000000000000000000000000000000004681 151.0
MMD2_k127_4065500_4 Sulfotransferase domain - - - 0.00000000000000002294 89.0
MMD2_k127_4065500_5 glycosyl transferase group 1 - - - 0.00000000007309 74.0
MMD2_k127_4081188_0 Cell surface protein - - - 0.00000000000001142 87.0
MMD2_k127_4094943_0 Trypsin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 416.0
MMD2_k127_4094943_1 Lytic transglycosylase catalytic K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001423 262.0
MMD2_k127_4094943_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000001085 129.0
MMD2_k127_4100794_0 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009645 428.0
MMD2_k127_4100794_1 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005346 288.0
MMD2_k127_4100794_2 Thiosulfate reductase cytochrome B subunit (Membrane anchoring protein) K03620,K08354 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000005696 251.0
MMD2_k127_4106430_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 558.0
MMD2_k127_4106430_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 338.0
MMD2_k127_4106430_2 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000002507 237.0
MMD2_k127_4106430_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000000000000000000000000000000000000000001815 201.0
MMD2_k127_4119530_0 Domains GAF, HisKA, HATPase_c, GAF, HD-GYP-related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 419.0
MMD2_k127_4119530_1 Bacterial regulatory proteins, crp family - - - 0.00000000000000000000000000000000002291 139.0
MMD2_k127_4125448_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.063e-246 774.0
MMD2_k127_4125448_1 phosphoglucosamine mutase activity K01835,K01840 - 5.4.2.2,5.4.2.8 1.392e-218 690.0
MMD2_k127_4125448_2 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007707 271.0
MMD2_k127_4125448_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000278 228.0
MMD2_k127_4142889_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.158e-217 696.0
MMD2_k127_4142889_1 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000002897 233.0
MMD2_k127_4142889_2 Protein of unknown function (DUF3124) - - - 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
MMD2_k127_4142889_3 - - - - 0.000000000000000000000000000000000000000002936 162.0
MMD2_k127_4142889_4 PFAM Tetratricopeptide repeat - - - 0.00000000000000001865 91.0
MMD2_k127_4142889_5 Domain of unknown function (DUF4912) K09942 - - 0.00000001809 67.0
MMD2_k127_4142889_6 Transport of potassium into the cell K03549 - - 0.0000001229 53.0
MMD2_k127_4166317_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 578.0
MMD2_k127_4166317_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002196 466.0
MMD2_k127_4166317_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004912 386.0
MMD2_k127_4166317_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0070180,GO:0071704,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000005585 204.0
MMD2_k127_4166317_4 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000185 179.0
MMD2_k127_4170028_0 BadF BadG BcrA BcrD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 398.0
MMD2_k127_4170028_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 347.0
MMD2_k127_4170028_10 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0003982 46.0
MMD2_k127_4170028_2 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002837 304.0
MMD2_k127_4170028_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000003483 248.0
MMD2_k127_4170028_4 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000392 225.0
MMD2_k127_4170028_5 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000006678 198.0
MMD2_k127_4170028_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000006383 79.0
MMD2_k127_4170028_8 Outer membrane lipoprotein carrier protein LolA K03634 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0030288,GO:0030313,GO:0031975,GO:0032940,GO:0033036,GO:0034613,GO:0042597,GO:0042886,GO:0042953,GO:0042954,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0051641,GO:0070727,GO:0071702,GO:0071705,GO:0072321,GO:0072322,GO:0072323,GO:0072657 - 0.0000000000000597 79.0
MMD2_k127_4170028_9 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000002665 68.0
MMD2_k127_4171457_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 531.0
MMD2_k127_4171457_1 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 374.0
MMD2_k127_4171457_2 Competence protein - GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0015976,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0005921 45.0
MMD2_k127_4171457_3 Thioredoxin K03672 - 1.8.1.8 0.0007889 49.0
MMD2_k127_4200852_0 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005357 517.0
MMD2_k127_4200852_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005182 286.0
MMD2_k127_4200852_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000008055 166.0
MMD2_k127_4200852_3 Hydrolase, TatD family K03424 - - 0.0000893 47.0
MMD2_k127_4204058_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007621 353.0
MMD2_k127_4204058_1 Mur ligase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 325.0
MMD2_k127_4204058_2 Sporulation related domain K03749 - - 0.00002573 54.0
MMD2_k127_4204058_3 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.000729 44.0
MMD2_k127_421623_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 359.0
MMD2_k127_421623_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 305.0
MMD2_k127_421623_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 299.0
MMD2_k127_421623_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000181 273.0
MMD2_k127_421623_4 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000167 165.0
MMD2_k127_421623_5 PBS lyase HEAT-like repeat - - - 0.00000000000002125 84.0
MMD2_k127_421623_6 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000001842 56.0
MMD2_k127_4224696_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.626e-234 734.0
MMD2_k127_4224696_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 9.907e-219 683.0
MMD2_k127_4224696_10 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001457 236.0
MMD2_k127_4224696_11 ThiS family K03636 - - 0.00000000000000000000000000000000005762 136.0
MMD2_k127_4224696_12 NIL - - - 0.000000000000000000000000002066 112.0
MMD2_k127_4224696_2 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006552 608.0
MMD2_k127_4224696_3 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 519.0
MMD2_k127_4224696_4 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 514.0
MMD2_k127_4224696_5 Polysaccharide biosynthesis protein K06409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002588 394.0
MMD2_k127_4224696_6 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 347.0
MMD2_k127_4224696_7 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 333.0
MMD2_k127_4224696_8 MazG nucleotide pyrophosphohydrolase domain K02428,K02499 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 331.0
MMD2_k127_4224696_9 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002528 270.0
MMD2_k127_4224798_0 - K07112 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000009057 67.0
MMD2_k127_4224798_1 Protein of unknown function (DUF3592) - - - 0.00000000807 67.0
MMD2_k127_4229443_0 Elongation factor SelB, winged helix K03833 - - 6.346e-214 681.0
MMD2_k127_4229443_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001672 471.0
MMD2_k127_4229443_10 Tetratricopeptide repeat - - - 0.0000008954 62.0
MMD2_k127_4229443_2 L-seryl-tRNASec selenium transferase activity K01042 GO:0003674,GO:0003824,GO:0004125,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016070,GO:0016259,GO:0016260,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0019752,GO:0019842,GO:0030170,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0090304,GO:0097056,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 460.0
MMD2_k127_4229443_3 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 417.0
MMD2_k127_4229443_4 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 356.0
MMD2_k127_4229443_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002406 279.0
MMD2_k127_4229443_6 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000001781 188.0
MMD2_k127_4229443_7 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000001024 178.0
MMD2_k127_4229443_8 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000001135 175.0
MMD2_k127_4229443_9 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000004944 151.0
MMD2_k127_4247769_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.875e-252 784.0
MMD2_k127_4247769_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.87e-245 765.0
MMD2_k127_4247769_10 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000003672 62.0
MMD2_k127_4247769_2 SMART Elongator protein 3 MiaB NifB K22226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008865 497.0
MMD2_k127_4247769_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 472.0
MMD2_k127_4247769_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 338.0
MMD2_k127_4247769_5 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000003691 215.0
MMD2_k127_4247769_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000874 156.0
MMD2_k127_4247769_7 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000009888 152.0
MMD2_k127_4247769_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000001051 134.0
MMD2_k127_4247769_9 ATP synthesis coupled proton transport K02109 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0016020,GO:0016469,GO:0032991,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045259,GO:0045260,GO:0071944,GO:0098796,GO:0098797 - 0.0000000000000000000000000871 111.0
MMD2_k127_4272839_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.415e-201 649.0
MMD2_k127_4272839_1 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003948 261.0
MMD2_k127_4272839_2 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000001454 166.0
MMD2_k127_4272839_3 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.00000000000000000000000000000008463 129.0
MMD2_k127_4272839_4 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000009922 68.0
MMD2_k127_427741_0 SMART Elongator protein 3 MiaB NifB - - - 4.11e-210 662.0
MMD2_k127_427741_1 Sulphur transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 431.0
MMD2_k127_427741_2 Protoporphyrinogen oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 358.0
MMD2_k127_427741_3 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002837 263.0
MMD2_k127_427741_4 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000001345 110.0
MMD2_k127_427741_5 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000001281 87.0
MMD2_k127_427741_7 COG0589 Universal stress protein UspA and related nucleotide-binding proteins - - - 0.000000004833 64.0
MMD2_k127_4291083_0 Cytochrome c554 and c-prime - - - 4.75e-241 752.0
MMD2_k127_4291083_1 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000156 257.0
MMD2_k127_4291083_2 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000006515 175.0
MMD2_k127_4291083_3 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000002255 152.0
MMD2_k127_4338389_0 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000004495 164.0
MMD2_k127_4338389_1 Histidine kinase - - - 0.00000000000000000000000000000000001996 151.0
MMD2_k127_4338389_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000004807 75.0
MMD2_k127_4344148_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000577 274.0
MMD2_k127_4344148_1 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000001046 234.0
MMD2_k127_4347494_0 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000002831 230.0
MMD2_k127_4347494_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000001358 213.0
MMD2_k127_4347494_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000003945 154.0
MMD2_k127_4347494_3 - - - - 0.00000000000000000000000003944 112.0
MMD2_k127_4350420_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 401.0
MMD2_k127_4350420_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000001357 205.0
MMD2_k127_4350420_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000006733 199.0
MMD2_k127_4350420_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000006997 145.0
MMD2_k127_4350420_4 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000003775 151.0
MMD2_k127_4350420_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000001756 72.0
MMD2_k127_4351353_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 354.0
MMD2_k127_4351353_1 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 309.0
MMD2_k127_4351353_2 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 309.0
MMD2_k127_4351353_3 PFAM ferredoxin - - - 0.00000000000000000000000000000000000000000000000000002909 196.0
MMD2_k127_4351353_4 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000002668 184.0
MMD2_k127_4351353_5 Domain of unknown function (DUF4124) K08309 - - 0.000000000000000000000000000000000000000007407 162.0
MMD2_k127_4351353_6 Putative regulatory protein - - - 0.000000000000000000000006174 104.0
MMD2_k127_4351353_7 PilZ domain - - - 0.00000000000002375 81.0
MMD2_k127_4363563_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.514e-205 645.0
MMD2_k127_4363563_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 2.394e-195 618.0
MMD2_k127_4363563_2 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000002176 213.0
MMD2_k127_4363563_3 tartrate metabolic process K01676,K01678 - 4.2.1.2 0.0000000000000000000000000000000000000008021 151.0
MMD2_k127_4363563_4 AMP binding - - - 0.00000000000000000000000000000001414 132.0
MMD2_k127_4363563_5 MOSC domain containing protein - - - 0.00000000000000000002179 91.0
MMD2_k127_4375292_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 589.0
MMD2_k127_4375292_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 329.0
MMD2_k127_4375292_2 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000003019 93.0
MMD2_k127_4375292_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000208 89.0
MMD2_k127_4375292_4 Protein of unknown function (DUF721) - - - 0.0000003774 59.0
MMD2_k127_4380274_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009981 420.0
MMD2_k127_4380274_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 355.0
MMD2_k127_4380274_10 DnaJ molecular chaperone homology domain - - - 0.000000004062 66.0
MMD2_k127_4380274_2 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 295.0
MMD2_k127_4380274_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000003874 199.0
MMD2_k127_4380274_4 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000001611 198.0
MMD2_k127_4380274_5 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000002833 150.0
MMD2_k127_4380274_6 Belongs to the ompA family K03640 - - 0.00000000000000000000000000000000000004216 152.0
MMD2_k127_4380274_7 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000738 147.0
MMD2_k127_4380274_8 energy transducer activity K03646,K03832 - - 0.00000000000000001968 91.0
MMD2_k127_4380274_9 GIY-YIG catalytic domain K07461 - - 0.000000000000002489 79.0
MMD2_k127_4389887_0 hydrophobe amphiphile efflux-3 (HAE3) family K07003 - - 0.0 1084.0
MMD2_k127_4389887_1 Sodium hydrogen exchanger K03455 - - 5.925e-229 726.0
MMD2_k127_4389887_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 382.0
MMD2_k127_4389887_3 S-layer protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 381.0
MMD2_k127_4389887_4 - - - - 0.000000000000000000000000000004797 126.0
MMD2_k127_4430476_0 membrane - - - 7.119e-244 763.0
MMD2_k127_4430476_1 Ammonium Transporter K03320 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 459.0
MMD2_k127_4430476_10 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000006451 172.0
MMD2_k127_4430476_11 Protein of unknown function (DUF2889) K07053 - 3.1.3.97 0.000000000000000000001483 104.0
MMD2_k127_4430476_12 - - - - 0.000000000000002689 76.0
MMD2_k127_4430476_13 Conserved hypothetical protein 698 - - - 0.0000000546 55.0
MMD2_k127_4430476_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006546 442.0
MMD2_k127_4430476_3 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 308.0
MMD2_k127_4430476_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007497 284.0
MMD2_k127_4430476_5 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006579 273.0
MMD2_k127_4430476_6 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001915 260.0
MMD2_k127_4430476_7 aminopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000232 254.0
MMD2_k127_4430476_8 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000000000000000000000000000000004672 206.0
MMD2_k127_4430476_9 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000003683 181.0
MMD2_k127_4431810_0 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001071 266.0
MMD2_k127_4431810_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000007746 208.0
MMD2_k127_4431810_2 MlaC protein K07323 - - 0.0000000000000000000000000000000000000000000000000000000006043 210.0
MMD2_k127_4451264_0 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003568 252.0
MMD2_k127_4451264_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000001804 132.0
MMD2_k127_445420_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 7.893e-280 865.0
MMD2_k127_445420_1 PFAM major facilitator superfamily MFS_1 K02575 - - 5.746e-242 754.0
MMD2_k127_445420_10 lyase activity - - - 0.000000000000000002181 93.0
MMD2_k127_445420_11 denitrification pathway K03532 - - 0.000004945 53.0
MMD2_k127_445420_12 PFAM CBS domain K07182 - - 0.00004733 48.0
MMD2_k127_445420_2 Nitrate reductase, beta subunit K00371,K17051 - 1.7.5.1 1.31e-234 734.0
MMD2_k127_445420_3 Nitrite sulfite reductase, hemoprotein beta-component, ferrodoxin domain protein K11181 GO:0003674,GO:0003824,GO:0005575,GO:0006790,GO:0008150,GO:0008152,GO:0009987,GO:0016002,GO:0016020,GO:0016491,GO:0016667,GO:0016673,GO:0019419,GO:0044237,GO:0050311,GO:0055114 1.8.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 332.0
MMD2_k127_445420_4 TIGRFAM respiratory nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 291.0
MMD2_k127_445420_5 Nitrite and sulphite reductase 4Fe-4S domain K11180,K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001322 286.0
MMD2_k127_445420_6 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004495 263.0
MMD2_k127_445420_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000004732 220.0
MMD2_k127_445420_8 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.000000000000000000000000000000000004498 144.0
MMD2_k127_445420_9 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000007572 99.0
MMD2_k127_4455760_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1110.0
MMD2_k127_4455760_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 360.0
MMD2_k127_4455760_10 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000002079 68.0
MMD2_k127_4455760_2 Cadherin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 368.0
MMD2_k127_4455760_3 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000000000000000000000000505 235.0
MMD2_k127_4455760_4 PFAM MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000004989 219.0
MMD2_k127_4455760_5 TIGRFAM molybdenum cofactor synthesis domain - - - 0.0000000000000000000000000000000000000000000000000000000007039 205.0
MMD2_k127_4455760_6 DNA polymerase K02347 - - 0.00000000000000000000000000000000000000158 150.0
MMD2_k127_4455760_7 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000989 106.0
MMD2_k127_4455760_9 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000002151 71.0
MMD2_k127_4496640_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 484.0
MMD2_k127_4496640_1 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 357.0
MMD2_k127_4496640_10 cytochrome c biogenesis protein - - - 0.00000000000000000000001086 106.0
MMD2_k127_4496640_11 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000103 96.0
MMD2_k127_4496640_12 cytochrome c biogenesis protein - - - 0.0000000002376 66.0
MMD2_k127_4496640_13 Rhodanese domain protein - - - 0.00000003955 58.0
MMD2_k127_4496640_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 359.0
MMD2_k127_4496640_3 Metal-dependent phosphohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004798 263.0
MMD2_k127_4496640_4 cytochrome complex assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000005877 244.0
MMD2_k127_4496640_5 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000642 232.0
MMD2_k127_4496640_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000008641 186.0
MMD2_k127_4496640_7 Glutathione peroxidase - - - 0.000000000000000000000000000000000000009025 151.0
MMD2_k127_4496640_8 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.00000000000000000000000000000000000004474 148.0
MMD2_k127_4496640_9 - - - - 0.00000000000000000000000000003636 122.0
MMD2_k127_4499000_0 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000004828 223.0
MMD2_k127_4499000_1 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000002603 152.0
MMD2_k127_4499000_2 peptidyl-tyrosine sulfation - - - 0.00000000001972 66.0
MMD2_k127_452196_0 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 439.0
MMD2_k127_452196_1 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001886 287.0
MMD2_k127_452196_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000001534 143.0
MMD2_k127_4525_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.552e-194 616.0
MMD2_k127_4525_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 600.0
MMD2_k127_4525_2 DNA recombination-mediator protein A K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 322.0
MMD2_k127_4525_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000002091 142.0
MMD2_k127_4526214_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 536.0
MMD2_k127_4526214_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 296.0
MMD2_k127_4526214_2 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000009527 269.0
MMD2_k127_4526214_3 Cytochrome c7 and related cytochrome c - - - 0.0000000000004018 73.0
MMD2_k127_4587193_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 456.0
MMD2_k127_4587193_1 belongs to the CobB CobQ family K06873 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 326.0
MMD2_k127_4587193_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 286.0
MMD2_k127_4587193_3 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002919 286.0
MMD2_k127_4587193_4 Protein tyrosine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000007148 241.0
MMD2_k127_4587193_5 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000001734 231.0
MMD2_k127_4587193_6 PFAM Protein phosphatase K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000001915 226.0
MMD2_k127_4587193_7 - - - - 0.0000000000000000008024 93.0
MMD2_k127_4590870_0 Glycosyl hydrolase family 57 - - - 2.051e-231 739.0
MMD2_k127_4590870_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 601.0
MMD2_k127_4590870_2 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 609.0
MMD2_k127_4590870_3 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003508 464.0
MMD2_k127_4590870_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000002822 171.0
MMD2_k127_4590870_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000001442 169.0
MMD2_k127_4590870_6 4Fe-4S binding domain - - - 0.0000000000000000000000000000000001716 138.0
MMD2_k127_4590870_7 - - - - 0.0000000000000000000000000004098 129.0
MMD2_k127_4590870_8 cell cycle K05589,K12065,K13052 - - 0.00000000005062 71.0
MMD2_k127_4593027_0 AcrB/AcrD/AcrF family - - - 2.724e-279 871.0
MMD2_k127_4593027_1 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 411.0
MMD2_k127_4593027_2 Belongs to the bacterial solute-binding protein 3 family K02030,K09969,K10039 - - 0.000000000000000000000000000000000000000000000000000000006803 208.0
MMD2_k127_4634208_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 582.0
MMD2_k127_4634208_1 Nitronate monooxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007564 526.0
MMD2_k127_4634208_10 YtkA-like - - - 0.0000000008293 65.0
MMD2_k127_4634208_2 Vacuole effluxer Atg22 like K06902 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 402.0
MMD2_k127_4634208_3 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 328.0
MMD2_k127_4634208_4 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 286.0
MMD2_k127_4634208_5 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004634 239.0
MMD2_k127_4634208_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000001268 183.0
MMD2_k127_4634208_7 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000001039 128.0
MMD2_k127_4634208_9 PilZ domain K02676 - - 0.0000000000002412 77.0
MMD2_k127_46447_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 438.0
MMD2_k127_46447_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.000000000000001058 77.0
MMD2_k127_46447_2 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000002665 64.0
MMD2_k127_4661150_0 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000003912 129.0
MMD2_k127_4661150_1 cyclic nucleotide binding K10914 - - 0.000000000000000000000000000002245 126.0
MMD2_k127_4661150_2 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000000000000000000001996 106.0
MMD2_k127_4661150_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000002369 81.0
MMD2_k127_4737993_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 413.0
MMD2_k127_4737993_1 B12 binding domain K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 376.0
MMD2_k127_4737993_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003502 280.0
MMD2_k127_4737993_3 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000004128 64.0
MMD2_k127_4746106_0 zinc ion binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009011 258.0
MMD2_k127_4746106_1 Lysin motif K08307 - - 0.00000000000000000000000000000000000001113 151.0
MMD2_k127_4746106_2 competence protein - - - 0.00000000000000000000000000000000001394 143.0
MMD2_k127_4746106_3 Tetratricopeptide repeat-like domain - - - 0.000000000000000166 89.0
MMD2_k127_4765678_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 6.8e-232 725.0
MMD2_k127_4765678_1 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 466.0
MMD2_k127_4765678_2 Phosphofructokinase K00850 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000009921 232.0
MMD2_k127_4766053_0 flavodoxin nitric oxide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 496.0
MMD2_k127_4766053_1 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 320.0
MMD2_k127_4766053_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000007538 124.0
MMD2_k127_4766053_3 Cysteine-rich small domain K07162 - - 0.0000000000000000006021 89.0
MMD2_k127_4766801_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.0000000000000000000000000000000001793 136.0
MMD2_k127_4766801_1 ribonuclease activity - - - 0.0000000000000000006593 92.0
MMD2_k127_4766801_2 Protein of unknown function (DUF433) - - - 0.000000000000000001812 86.0
MMD2_k127_4766801_3 CopG domain protein DNA-binding domain protein - - - 0.00000000000000218 78.0
MMD2_k127_4781625_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.689e-298 928.0
MMD2_k127_4781625_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 1.088e-270 851.0
MMD2_k127_4781625_10 domain, Protein - - - 0.00008692 57.0
MMD2_k127_4781625_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 3.413e-223 701.0
MMD2_k127_4781625_3 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 493.0
MMD2_k127_4781625_4 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 371.0
MMD2_k127_4781625_5 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 355.0
MMD2_k127_4781625_6 domain protein K01637,K20276 - 4.1.3.1 0.00000000000000000000000000000000000000000000000000000000006247 236.0
MMD2_k127_4781625_7 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000001147 151.0
MMD2_k127_4781625_8 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.00000000000000000007942 107.0
MMD2_k127_4781625_9 amine dehydrogenase activity - - - 0.00000000000001422 89.0
MMD2_k127_4782047_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 496.0
MMD2_k127_4782047_1 Predicted permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 477.0
MMD2_k127_4782047_2 Putative Fe-S cluster - - - 0.000000000000000000000000000000000000000002261 158.0
MMD2_k127_4782047_3 Domain of unknown function (DUF2703) - - - 0.000000000000000000000000000000000005383 141.0
MMD2_k127_4782047_4 Thioredoxin domain - - - 0.000000000000000000001114 96.0
MMD2_k127_47967_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 604.0
MMD2_k127_47967_1 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 347.0
MMD2_k127_47967_2 xyloglucan:xyloglucosyl transferase activity K20846 - 3.2.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 332.0
MMD2_k127_47967_3 Rare lipoprotein A K20628 - - 0.000000000000000000000000000000000000000000000001945 175.0
MMD2_k127_47967_4 - - - - 0.000000000000000000000000000000000000000000000003789 176.0
MMD2_k127_47967_5 Rhodanese Homology Domain - - - 0.000000000000000000000000001689 116.0
MMD2_k127_47967_6 Trypsin-like peptidase domain - - - 0.00000000000000000000000008022 122.0
MMD2_k127_480247_0 Poly-beta-hydroxybutyrate polymerase N terminal K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 559.0
MMD2_k127_480247_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 383.0
MMD2_k127_480247_2 Poly-beta-hydroxybutyrate polymerase K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000008403 236.0
MMD2_k127_480247_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000269 223.0
MMD2_k127_480247_4 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000001795 192.0
MMD2_k127_480247_5 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000157 136.0
MMD2_k127_4804687_0 FAD binding domain K00278 - 1.4.3.16 3.216e-199 634.0
MMD2_k127_4804687_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 573.0
MMD2_k127_4804687_10 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 304.0
MMD2_k127_4804687_11 metal-dependent enzyme K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 298.0
MMD2_k127_4804687_12 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.000000000000000000000000000000000000000000000000000000000000000000005007 244.0
MMD2_k127_4804687_13 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000000000000000000000000006419 197.0
MMD2_k127_4804687_14 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000002322 168.0
MMD2_k127_4804687_15 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000005442 157.0
MMD2_k127_4804687_16 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000004646 133.0
MMD2_k127_4804687_17 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000001051 118.0
MMD2_k127_4804687_18 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000305 111.0
MMD2_k127_4804687_19 - - - - 0.0000000000000000000000001124 107.0
MMD2_k127_4804687_2 DHHA2 domain K15986 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 564.0
MMD2_k127_4804687_20 phosphorelay signal transduction system - - - 0.00000000000000000000006367 102.0
MMD2_k127_4804687_21 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000001092 98.0
MMD2_k127_4804687_22 cheY-homologous receiver domain - - - 0.0000000000000005805 81.0
MMD2_k127_4804687_23 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000000000003157 80.0
MMD2_k127_4804687_24 conserved protein (DUF2081) - - - 0.0000000000003451 73.0
MMD2_k127_4804687_25 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000007102 69.0
MMD2_k127_4804687_26 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00001316 53.0
MMD2_k127_4804687_27 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000228 46.0
MMD2_k127_4804687_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 554.0
MMD2_k127_4804687_4 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007511 539.0
MMD2_k127_4804687_5 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007881 507.0
MMD2_k127_4804687_6 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 494.0
MMD2_k127_4804687_7 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 476.0
MMD2_k127_4804687_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 473.0
MMD2_k127_4804687_9 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 452.0
MMD2_k127_4838394_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 606.0
MMD2_k127_4838394_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007634 408.0
MMD2_k127_4838394_10 - - - - 0.0000000000000000000007396 97.0
MMD2_k127_4838394_11 Translation Initiation Factor K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043024,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000004235 89.0
MMD2_k127_4838394_12 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000002962 82.0
MMD2_k127_4838394_13 transferase activity, transferring glycosyl groups - - - 0.00000002482 61.0
MMD2_k127_4838394_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 378.0
MMD2_k127_4838394_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000099 253.0
MMD2_k127_4838394_4 Cytochrome P460 - - - 0.00000000000000000000000000000000000000002349 159.0
MMD2_k127_4838394_5 methyltransferase activity - - - 0.00000000000000000000000000000000000000008925 158.0
MMD2_k127_4838394_6 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000003714 148.0
MMD2_k127_4838394_7 L,D-transpeptidase catalytic domain K16291 - - 0.00000000000000000000000000000000836 130.0
MMD2_k127_4838394_8 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000000000000002561 116.0
MMD2_k127_4838394_9 SMART Cold shock protein K03704 - - 0.0000000000000000000000000005539 114.0
MMD2_k127_4842808_0 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000002793 235.0
MMD2_k127_4842808_1 - - - - 0.000000000000000000003969 98.0
MMD2_k127_4842808_2 WYL domain K13573 - - 0.000000000003587 68.0
MMD2_k127_4842808_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0009216 50.0
MMD2_k127_4861907_0 ZIP Zinc transporter K07238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 407.0
MMD2_k127_4861907_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 377.0
MMD2_k127_4861907_2 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000001935 220.0
MMD2_k127_4861907_3 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000125 187.0
MMD2_k127_4861907_4 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000001671 168.0
MMD2_k127_4861907_5 FHA domain GGDEF domain protein - - - 0.00003188 47.0
MMD2_k127_488921_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001922 279.0
MMD2_k127_488921_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000004467 217.0
MMD2_k127_488921_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000002977 202.0
MMD2_k127_488921_3 cyclic diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000005749 156.0
MMD2_k127_4907476_0 Cell shape determining protein MreB Mrl K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000001534 241.0
MMD2_k127_4907476_1 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000009149 139.0
MMD2_k127_4907476_2 diguanylate cyclase K02488 - 2.7.7.65 0.00002103 56.0
MMD2_k127_4927767_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 1.816e-241 755.0
MMD2_k127_4927767_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 4.574e-234 740.0
MMD2_k127_4927767_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.83e-227 713.0
MMD2_k127_4927767_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 478.0
MMD2_k127_4927767_4 Arginyl-tRNA synthetase K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 464.0
MMD2_k127_4927767_5 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006659 317.0
MMD2_k127_4927767_6 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006733 280.0
MMD2_k127_4927767_7 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000001867 115.0
MMD2_k127_4927767_8 - - - - 0.0000000000000000000000003445 115.0
MMD2_k127_4927767_9 transcription factor binding K10941 - - 0.0000000000000000000001736 104.0
MMD2_k127_4958055_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005998 313.0
MMD2_k127_4958055_1 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000001277 260.0
MMD2_k127_4958055_2 - K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000001961 241.0
MMD2_k127_4958055_3 HNH nucleases - - - 0.0000000000000000000000000000000000000000001934 160.0
MMD2_k127_4958055_4 - - - - 0.00000000000001925 76.0
MMD2_k127_4958055_5 transglycosylase K08309 - - 0.000001047 59.0
MMD2_k127_4976632_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1543.0
MMD2_k127_4976632_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.454e-205 646.0
MMD2_k127_4976632_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000000000000002599 169.0
MMD2_k127_4976632_11 Pas domain K13069 - 2.7.7.65 0.00000000000000000000000000000000000001093 158.0
MMD2_k127_4976632_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000004493 88.0
MMD2_k127_4976632_2 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 557.0
MMD2_k127_4976632_3 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007388 496.0
MMD2_k127_4976632_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0030312,GO:0031406,GO:0034618,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 366.0
MMD2_k127_4976632_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000246 338.0
MMD2_k127_4976632_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 319.0
MMD2_k127_4976632_7 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000009688 260.0
MMD2_k127_4976632_8 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000002461 234.0
MMD2_k127_4976632_9 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000002344 219.0
MMD2_k127_4978105_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 545.0
MMD2_k127_4978105_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002375 524.0
MMD2_k127_4978105_10 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000002141 124.0
MMD2_k127_4978105_11 PFAM CheW domain protein K03408 - - 0.0000000000000000003703 96.0
MMD2_k127_4978105_12 Histidine kinase A domain protein K02482,K14986 - 2.7.13.3 0.000000000009521 66.0
MMD2_k127_4978105_2 Pfam:Arch_ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 288.0
MMD2_k127_4978105_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000079 312.0
MMD2_k127_4978105_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009124 273.0
MMD2_k127_4978105_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000001236 261.0
MMD2_k127_4978105_6 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000006294 198.0
MMD2_k127_4978105_7 regulator, PATAN and FRGAF domain-containing - - - 0.00000000000000000000000000000000000000000002313 176.0
MMD2_k127_4978105_8 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000006119 148.0
MMD2_k127_4978105_9 PFAM CheW-like domain K03408 - - 0.00000000000000000000000000000006436 130.0
MMD2_k127_4988010_0 TIGRFAM ATP-dependent helicase HrpB K03579 - 3.6.4.13 3.689e-278 879.0
MMD2_k127_4988010_1 Bacterial protein of unknown function (DUF853) K06915 - - 4.443e-217 682.0
MMD2_k127_4988010_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 593.0
MMD2_k127_4988010_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000468 215.0
MMD2_k127_4988010_4 - - - - 0.00000000000000000000000000427 113.0
MMD2_k127_4988010_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000009878 74.0
MMD2_k127_4998325_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 440.0
MMD2_k127_4998325_1 HlyD family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 289.0
MMD2_k127_4998325_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006808 243.0
MMD2_k127_4998325_3 cheY-homologous receiver domain - - - 0.0005888 46.0
MMD2_k127_5011614_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 559.0
MMD2_k127_5011614_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 520.0
MMD2_k127_5011614_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000272 199.0
MMD2_k127_5011614_3 2 iron, 2 sulfur cluster binding K00334,K00335 - 1.6.5.3 0.000000000000000000000000000000000000000002228 161.0
MMD2_k127_5036147_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 8.607e-204 651.0
MMD2_k127_5036147_1 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.000000000000000000000002702 106.0
MMD2_k127_5036147_2 Histidine kinase - - - 0.0000009344 54.0
MMD2_k127_5042058_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1073.0
MMD2_k127_5042058_1 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 593.0
MMD2_k127_5056975_0 PFAM HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001071 264.0
MMD2_k127_5056975_1 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006353 239.0
MMD2_k127_5056975_2 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003588 235.0
MMD2_k127_5056975_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000001736 219.0
MMD2_k127_5056975_4 PFAM CBS domain - - - 0.00000000000000000000000000000000000000000000000001456 185.0
MMD2_k127_5056975_5 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000003237 151.0
MMD2_k127_5056975_6 - - - - 0.00000000000000000000000000000000000004456 146.0
MMD2_k127_5064964_0 ABC transporter K06020 - 3.6.3.25 3.567e-242 751.0
MMD2_k127_5064964_1 PFAM PhoH-like protein K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 384.0
MMD2_k127_5064964_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005124 278.0
MMD2_k127_5064964_3 Methylates ribosomal protein L11 K02687 - - 0.00000000000000000000000000000000000000000003757 173.0
MMD2_k127_5065344_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 466.0
MMD2_k127_5065344_1 PFAM Peptidase C26 K07010 - - 0.00001903 49.0
MMD2_k127_5065667_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 369.0
MMD2_k127_5065667_1 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 333.0
MMD2_k127_5065667_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000001605 185.0
MMD2_k127_5087410_0 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000002281 169.0
MMD2_k127_5087410_1 Auxin Efflux Carrier K07088 - - 0.0000000000000000000000000000000000000000000003486 179.0
MMD2_k127_5087410_3 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000002084 100.0
MMD2_k127_5087410_4 phosphorelay signal transduction system - - - 0.00000000000000000004909 100.0
MMD2_k127_5087410_5 Cbs domain - - - 0.0000000008194 63.0
MMD2_k127_5107983_0 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004852 408.0
MMD2_k127_5107983_1 - - - - 0.000000000000000000000000000000000000000000000000000001458 206.0
MMD2_k127_5107983_2 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000001676 175.0
MMD2_k127_5131588_0 DNA polymerase Ligase (LigD) - - - 2.373e-316 986.0
MMD2_k127_5131588_1 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 400.0
MMD2_k127_5131588_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 334.0
MMD2_k127_5131588_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000134 261.0
MMD2_k127_5131588_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000001597 199.0
MMD2_k127_5131588_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000402 162.0
MMD2_k127_5189144_0 Lytic transglycosylase, SLT, LysM and LysM domain-containing K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008288 265.0
MMD2_k127_5189144_1 smart pdz dhr glgf K04771 - 3.4.21.107 0.000000000001993 68.0
MMD2_k127_5212418_0 Domains REC, sigma54 interaction, HTH8 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 434.0
MMD2_k127_5212418_1 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000008032 120.0
MMD2_k127_5212418_2 heat shock protein binding - - - 0.00001803 58.0
MMD2_k127_5222039_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 426.0
MMD2_k127_5222039_1 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 402.0
MMD2_k127_5226243_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 398.0
MMD2_k127_5226243_1 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 314.0
MMD2_k127_5226243_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000008097 238.0
MMD2_k127_5226243_3 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000004814 168.0
MMD2_k127_5226243_4 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000001725 147.0
MMD2_k127_5226243_5 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.000000001824 65.0
MMD2_k127_5284883_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 338.0
MMD2_k127_5284883_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 314.0
MMD2_k127_5284883_2 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.00000000000000000000000000000000000000004639 154.0
MMD2_k127_5284883_3 peptidyl-tyrosine sulfation - - - 0.0000004715 59.0
MMD2_k127_5389067_0 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 287.0
MMD2_k127_5389067_1 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000000000000008941 233.0
MMD2_k127_5389067_2 DUF1264-domain-containing protein - - - 0.000000000001507 74.0
MMD2_k127_5389067_3 Protein of unknown function (DUF1353) - - - 0.00006446 47.0
MMD2_k127_5401193_0 Aminotransferase class I and II K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 565.0
MMD2_k127_5401193_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004611 372.0
MMD2_k127_5401193_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 325.0
MMD2_k127_5401193_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000008377 106.0
MMD2_k127_5408473_0 belongs to the bacterial solute-binding protein 3 family K02030,K09969,K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 360.0
MMD2_k127_5408473_1 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006065 281.0
MMD2_k127_5408473_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000206 269.0
MMD2_k127_5408473_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000159 186.0
MMD2_k127_5408473_4 Citrate transporter - - - 0.00000000000001521 78.0
MMD2_k127_5426301_0 4Fe-4S dicluster domain - - - 7.684e-305 940.0
MMD2_k127_5426301_1 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 423.0
MMD2_k127_5426301_2 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000000000000001243 186.0
MMD2_k127_5426301_3 - - - - 0.00000000000000000000000000000000000000000000004332 178.0
MMD2_k127_5426301_4 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.0000000000000000000000000000000000000000000003376 172.0
MMD2_k127_5426301_5 4 iron, 4 sulfur cluster binding K00184 - - 0.00000000000000000000000000113 116.0
MMD2_k127_5426301_6 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.0000000000000000000005736 105.0
MMD2_k127_5426301_7 lyase activity - - - 0.00000000000002006 78.0
MMD2_k127_5426301_8 lyase activity - - - 0.000000000005078 74.0
MMD2_k127_5426301_9 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000004449 60.0
MMD2_k127_5470914_0 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 565.0
MMD2_k127_5470914_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 466.0
MMD2_k127_5470914_2 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 412.0
MMD2_k127_5470914_3 Diphthamide synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002648 273.0
MMD2_k127_5470914_4 (ABC) transporter K02028,K02029 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000135 246.0
MMD2_k127_5470914_5 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000003066 179.0
MMD2_k127_5470914_6 Diguanylate cyclase - - - 0.000000000000000000000000000000002818 149.0
MMD2_k127_5470914_7 sulfur carrier activity K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000000000000000001002 96.0
MMD2_k127_5470914_8 - - - - 0.0000000000000005767 78.0
MMD2_k127_5497150_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 571.0
MMD2_k127_5497150_1 Citrate synthase, C-terminal domain K01647,K01659 - 2.3.3.1,2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 404.0
MMD2_k127_5507574_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.409e-320 1003.0
MMD2_k127_5507574_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.149e-277 866.0
MMD2_k127_5507574_10 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 339.0
MMD2_k127_5507574_11 Histidine kinase K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 331.0
MMD2_k127_5507574_12 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 291.0
MMD2_k127_5507574_13 FMN binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001875 272.0
MMD2_k127_5507574_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001385 248.0
MMD2_k127_5507574_15 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000006471 233.0
MMD2_k127_5507574_16 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000000000000000000000000677 188.0
MMD2_k127_5507574_17 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008104,GO:0008150,GO:0009966,GO:0010646,GO:0010738,GO:0023051,GO:0033036,GO:0034237,GO:0044424,GO:0044444,GO:0044464,GO:0048583,GO:0050789,GO:0050794,GO:0051018,GO:0051179,GO:0065007,GO:1902531 3.1.4.58 0.00000000000000000000000000000000002346 141.0
MMD2_k127_5507574_18 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.000000000000000000000000001293 118.0
MMD2_k127_5507574_19 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.000000000000000000000008015 106.0
MMD2_k127_5507574_2 Sugar (and other) transporter K03446 - - 2.022e-228 719.0
MMD2_k127_5507574_20 RecX family K03565 - - 0.0000003519 58.0
MMD2_k127_5507574_22 - - - - 0.0001879 47.0
MMD2_k127_5507574_23 ATP synthase, subunit b - - - 0.0005146 47.0
MMD2_k127_5507574_3 Sigma-54 interaction domain - - - 2.109e-206 651.0
MMD2_k127_5507574_4 membrane transporter protein K07090 - - 1.403e-203 641.0
MMD2_k127_5507574_5 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 555.0
MMD2_k127_5507574_6 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 501.0
MMD2_k127_5507574_7 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009542 497.0
MMD2_k127_5507574_8 Sigma-54 interaction domain K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 433.0
MMD2_k127_5507574_9 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000965 366.0
MMD2_k127_5514349_0 MCP methyltransferase, CheR-type K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 308.0
MMD2_k127_5514349_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000593 216.0
MMD2_k127_5514349_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000001931 215.0
MMD2_k127_5519486_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 518.0
MMD2_k127_5519486_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000000000000000000000000000000000000002054 160.0
MMD2_k127_5519486_2 nuclease activity - - - 0.000000000000000000000000000000000000000005879 157.0
MMD2_k127_5519486_3 MgtC family K07507 - - 0.0000000000000000000000000000000000005187 148.0
MMD2_k127_5519486_4 - - - - 0.000000000000000000007847 97.0
MMD2_k127_5519486_5 - - - - 0.00000000000000000000839 93.0
MMD2_k127_5519486_7 NUDIX domain K01515 - 3.6.1.13 0.000007976 48.0
MMD2_k127_5522590_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1128.0
MMD2_k127_5522590_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 512.0
MMD2_k127_5522590_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000111 134.0
MMD2_k127_5522590_3 response regulator, receiver K03413 - - 0.00000000000000002745 87.0
MMD2_k127_5577239_0 Nitrite and sulphite reductase 4Fe-4S K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 556.0
MMD2_k127_5577239_1 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 554.0
MMD2_k127_5577239_2 Nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 337.0
MMD2_k127_5577239_3 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001946 284.0
MMD2_k127_5577239_4 GDP-mannose mannosyl hydrolase activity - - - 0.000000000000000002043 87.0
MMD2_k127_5577239_5 - - - - 0.00001004 51.0
MMD2_k127_5580183_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 1.103e-280 875.0
MMD2_k127_5580183_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000001229 206.0
MMD2_k127_5580183_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000008714 194.0
MMD2_k127_5580183_3 Membrane - - - 0.000000000000000000000000000000000002031 142.0
MMD2_k127_5580183_4 Protein of unknown function (DUF3617) - - - 0.00000000000000000000000117 109.0
MMD2_k127_5581367_0 Heat shock 70 kDa protein K04043 - - 3.21e-317 980.0
MMD2_k127_5581367_1 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 488.0
MMD2_k127_5581367_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 445.0
MMD2_k127_5581367_3 spermidine synthase activity K00797 GO:0003674,GO:0003824,GO:0004766,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 411.0
MMD2_k127_5581367_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 294.0
MMD2_k127_5581367_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000142 261.0
MMD2_k127_5581367_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000008139 152.0
MMD2_k127_5581367_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000001123 143.0
MMD2_k127_5601935_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004011 499.0
MMD2_k127_5601935_1 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002416 250.0
MMD2_k127_5601935_2 PFAM Dinitrogenase iron-molybdenum cofactor biosynthesis protein - - - 0.000000000000000000000000000000000000000002692 160.0
MMD2_k127_5601935_3 Protein of unknown function DUF134 - - - 0.0000000000000000000000000004437 115.0
MMD2_k127_5601935_4 PFAM DsrE DsrF-like family - - - 0.00000001564 61.0
MMD2_k127_5616824_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 424.0
MMD2_k127_5616824_1 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000085 269.0
MMD2_k127_5616824_2 Zinc dependent phospholipase C - - - 0.000000000000000000000000000000000000000000000000000000742 203.0
MMD2_k127_5616824_3 HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.00000000000000000000004508 101.0
MMD2_k127_5622284_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1022.0
MMD2_k127_5622284_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 379.0
MMD2_k127_5622284_2 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000007865 239.0
MMD2_k127_5622284_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000005313 122.0
MMD2_k127_5638689_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 328.0
MMD2_k127_5638689_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007653 272.0
MMD2_k127_5638689_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000002442 240.0
MMD2_k127_5638689_3 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000001064 215.0
MMD2_k127_564314_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1211.0
MMD2_k127_564314_1 NADH dehydrogenase - - - 2.917e-216 695.0
MMD2_k127_564314_10 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000168 209.0
MMD2_k127_564314_11 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000006543 131.0
MMD2_k127_564314_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000001842 109.0
MMD2_k127_564314_13 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0000000000000000000000004487 107.0
MMD2_k127_564314_14 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000004329 57.0
MMD2_k127_564314_15 Uncharacterized protein conserved in bacteria (DUF2059) - - - 0.00001104 57.0
MMD2_k127_564314_16 Bacterial protein of unknown function (DUF922) - - - 0.0001172 53.0
MMD2_k127_564314_2 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336,K05299,K06441 - 1.12.7.2,1.17.1.10,1.17.1.9,1.6.5.3 4.182e-208 672.0
MMD2_k127_564314_3 Ftsk_gamma K03466 - - 1.633e-198 644.0
MMD2_k127_564314_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009245 580.0
MMD2_k127_564314_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 386.0
MMD2_k127_564314_6 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 353.0
MMD2_k127_564314_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 291.0
MMD2_k127_564314_8 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003712 280.0
MMD2_k127_564314_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain - - - 0.000000000000000000000000000000000000000000000000000000000000144 218.0
MMD2_k127_5643858_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 3.531e-227 718.0
MMD2_k127_5643858_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001229 267.0
MMD2_k127_5643858_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000002904 179.0
MMD2_k127_5643858_3 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000004947 114.0
MMD2_k127_5643858_4 SMART Cold shock protein K03704 - - 0.00000000000000000000000001443 112.0
MMD2_k127_5646671_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000009597 254.0
MMD2_k127_5646671_1 ABC transporter K03701 - - 0.00000000000000000000000000000000000000000000000000000001496 199.0
MMD2_k127_5646671_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000008055 179.0
MMD2_k127_5646671_3 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00000000000000000000000000000000003596 140.0
MMD2_k127_5646671_4 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000008331 78.0
MMD2_k127_5646671_5 NusG domain II - - - 0.00000000007797 67.0
MMD2_k127_5656220_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.175e-262 821.0
MMD2_k127_5656220_1 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003809 252.0
MMD2_k127_5656220_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000002807 151.0
MMD2_k127_5656220_3 - - - - 0.00000001729 65.0
MMD2_k127_5716480_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002713 574.0
MMD2_k127_5716480_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 533.0
MMD2_k127_5716480_2 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 402.0
MMD2_k127_5716480_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000004557 215.0
MMD2_k127_5716480_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000001839 202.0
MMD2_k127_5716480_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.0000000000000000000000000000000000000000000000000001911 193.0
MMD2_k127_5716480_6 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000008727 114.0
MMD2_k127_5716480_7 ATPase (AAA superfamily K07133 - - 0.00000000000102 77.0
MMD2_k127_5721108_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 5.095e-196 621.0
MMD2_k127_5721108_1 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 345.0
MMD2_k127_5721108_2 PFAM major facilitator superfamily MFS_1 K08223 - - 0.000000000000000000000000000000000000000000000000000000000000000002554 241.0
MMD2_k127_5721108_3 Protein of unknown function (DUF1189) - - - 0.000000000000000000000000000000001717 139.0
MMD2_k127_5721108_4 CO dehydrogenase acetyl-CoA synthase gamma subunit (Corrinoid Fe-S protein) - - - 0.0000000000000000005188 92.0
MMD2_k127_5721108_5 EAL domain protein - - - 0.000000000002257 75.0
MMD2_k127_5725817_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 449.0
MMD2_k127_5725817_1 Histidine kinase K07641,K07642,K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000125 273.0
MMD2_k127_5725817_2 phosphatidate phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000003586 237.0
MMD2_k127_5725817_3 Transcriptional regulatory protein, C terminal K07776 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009405,GO:0009889,GO:0010468,GO:0010556,GO:0010565,GO:0019216,GO:0019217,GO:0019219,GO:0019220,GO:0019222,GO:0031323,GO:0031326,GO:0044419,GO:0048583,GO:0050789,GO:0050794,GO:0051171,GO:0051174,GO:0051252,GO:0051704,GO:0060255,GO:0062012,GO:0065007,GO:0080090,GO:0080134,GO:0097159,GO:1901363,GO:1902882,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000001093 205.0
MMD2_k127_5725817_4 RNA-binding protein containing a PIN domain K06962 - - 0.000000000000000000000000000000002307 134.0
MMD2_k127_5725817_5 Helix-turn-helix domain K02806 - - 0.000000000000000000000000000002717 128.0
MMD2_k127_5725817_6 Belongs to the UPF0235 family K09131 - - 0.000000001537 63.0
MMD2_k127_573563_0 PFAM PfkB K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 385.0
MMD2_k127_573563_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008679 267.0
MMD2_k127_573563_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000002603 78.0
MMD2_k127_5741918_0 protein secretion K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 559.0
MMD2_k127_5741918_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005296 451.0
MMD2_k127_5741918_2 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 330.0
MMD2_k127_5741918_3 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008218 331.0
MMD2_k127_5741918_4 helix_turn_helix gluconate operon transcriptional repressor K03710 - - 0.0000000000000000000000000000000044 138.0
MMD2_k127_5747900_0 FAD binding domain K00394 - 1.8.99.2 0.0 1045.0
MMD2_k127_5747900_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 6.4e-323 1002.0
MMD2_k127_5747900_2 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.616e-276 860.0
MMD2_k127_5747900_3 FAD dependent oxidoreductase K16885 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 484.0
MMD2_k127_5747900_4 nitrate reductase activity K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 397.0
MMD2_k127_5747900_5 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000009122 154.0
MMD2_k127_5747900_6 FAD dependent oxidoreductase K16885 - - 0.000000000000000000000003385 104.0
MMD2_k127_5747900_7 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000008685 106.0
MMD2_k127_5750616_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1011.0
MMD2_k127_5750616_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 559.0
MMD2_k127_5750616_10 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003142 269.0
MMD2_k127_5750616_11 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005081 276.0
MMD2_k127_5750616_12 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005187 277.0
MMD2_k127_5750616_13 SEC-C motif K09858 - - 0.0000000000000000000000000000000000000000000000000000000000005455 214.0
MMD2_k127_5750616_14 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000004757 212.0
MMD2_k127_5750616_15 - - - - 0.000000000000000000000000000000000000000000000000000001873 202.0
MMD2_k127_5750616_16 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000004773 179.0
MMD2_k127_5750616_17 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000008798 87.0
MMD2_k127_5750616_18 Belongs to the UPF0434 family K09791 - - 0.0000000000000000724 81.0
MMD2_k127_5750616_19 - - - - 0.0000000000002194 72.0
MMD2_k127_5750616_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 553.0
MMD2_k127_5750616_22 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000005769 48.0
MMD2_k127_5750616_23 type IV pilus assembly PilZ - - - 0.0000259 51.0
MMD2_k127_5750616_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 509.0
MMD2_k127_5750616_4 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 461.0
MMD2_k127_5750616_5 response regulator K07712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 404.0
MMD2_k127_5750616_6 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 388.0
MMD2_k127_5750616_7 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 347.0
MMD2_k127_5750616_8 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 322.0
MMD2_k127_5750616_9 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009102 290.0
MMD2_k127_5755367_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 3.588e-261 814.0
MMD2_k127_5755367_1 PFAM ferredoxin-dependent glutamate synthase - - - 8.508e-246 764.0
MMD2_k127_5755367_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004699 446.0
MMD2_k127_5755367_3 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005656 382.0
MMD2_k127_5755367_4 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000245 263.0
MMD2_k127_5755367_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000004094 205.0
MMD2_k127_5755367_6 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000246 204.0
MMD2_k127_5755367_7 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000175 179.0
MMD2_k127_5755367_8 thiamine diphosphate biosynthetic process K03154 - - 0.00000000002973 67.0
MMD2_k127_5777984_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1167.0
MMD2_k127_5777984_1 Aminotransferase class I and II K14261 - - 3.787e-213 666.0
MMD2_k127_5777984_10 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.000000000000000000000000000000000000000000000000000000001328 204.0
MMD2_k127_5777984_11 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000000002089 115.0
MMD2_k127_5777984_12 Tetratricopeptide repeat - - - 0.0000000000001205 80.0
MMD2_k127_5777984_14 - - - - 0.0004264 51.0
MMD2_k127_5777984_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 529.0
MMD2_k127_5777984_3 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 424.0
MMD2_k127_5777984_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 408.0
MMD2_k127_5777984_5 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 379.0
MMD2_k127_5777984_6 ThiF family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 362.0
MMD2_k127_5777984_7 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008792 327.0
MMD2_k127_5777984_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 304.0
MMD2_k127_5777984_9 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000002111 219.0
MMD2_k127_5779007_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009293 482.0
MMD2_k127_5779007_1 Putative Fe-S cluster K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 342.0
MMD2_k127_5779007_2 Part of a membrane complex involved in electron transport K03617 - - 0.000000000000000000000000000000000000000000000000000000000000000000293 234.0
MMD2_k127_5779007_3 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000001546 210.0
MMD2_k127_5779007_4 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000003001 200.0
MMD2_k127_5779007_5 Part of a membrane complex involved in electron transport K03614 - - 0.00000000000000000000000000000000000000002265 155.0
MMD2_k127_5779007_6 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000001359 114.0
MMD2_k127_5781702_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 456.0
MMD2_k127_5781702_1 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009328 336.0
MMD2_k127_5781702_2 ABC transporter K01996 - - 0.000000000000000001989 85.0
MMD2_k127_5784880_0 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 379.0
MMD2_k127_5784880_1 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 367.0
MMD2_k127_5784880_2 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 346.0
MMD2_k127_5784880_3 ABC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006075 290.0
MMD2_k127_5784880_4 UPF0056 membrane protein K05595 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000005651 194.0
MMD2_k127_5784880_5 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000001785 175.0
MMD2_k127_5784880_6 radical SAM domain protein - - - 0.0000000000000000000000000000003163 137.0
MMD2_k127_5784880_7 Type II secretion system protein B K02451 - - 0.00000000000000000000004619 108.0
MMD2_k127_5784880_8 Uncharacterized conserved protein (DUF2196) - - - 0.00000000000000000000005169 101.0
MMD2_k127_5785988_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 3.519e-226 724.0
MMD2_k127_5792427_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 331.0
MMD2_k127_5792427_1 HD domain K06950 - - 0.000000000000000000000000000000000000000000000000000000008055 201.0
MMD2_k127_5797016_0 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 424.0
MMD2_k127_5797016_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 315.0
MMD2_k127_5812873_0 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001527 297.0
MMD2_k127_5812873_1 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000004632 233.0
MMD2_k127_5812873_2 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.000000000000000000000000000000000000000000000000000000004914 202.0
MMD2_k127_5812873_3 metalloendopeptidase activity K03799 - - 0.0000000000000000000000007 116.0
MMD2_k127_5812873_4 SMART chemotaxis sensory transducer, histidine kinase HAMP region domain protein K03406 - - 0.0000003827 60.0
MMD2_k127_5814127_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 599.0
MMD2_k127_5814127_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 610.0
MMD2_k127_5814127_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 455.0
MMD2_k127_5814127_3 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 377.0
MMD2_k127_5814127_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 305.0
MMD2_k127_5814127_5 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000001041 207.0
MMD2_k127_5814127_6 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000001005 175.0
MMD2_k127_5825100_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 489.0
MMD2_k127_5825100_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000001503 214.0
MMD2_k127_5825100_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000005929 194.0
MMD2_k127_5825100_3 PFAM response regulator receiver - - - 0.0000000000000000000000000001784 119.0
MMD2_k127_5851617_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 562.0
MMD2_k127_5851617_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 332.0
MMD2_k127_5851617_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000000000000000000211 154.0
MMD2_k127_5851617_3 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.00000000000000000000000000000000001745 143.0
MMD2_k127_5851617_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.00000000000000000000000000000000004008 136.0
MMD2_k127_5851617_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000003885 112.0
MMD2_k127_5851617_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000004367 48.0
MMD2_k127_5924179_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 594.0
MMD2_k127_5924179_1 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001969 248.0
MMD2_k127_5924179_2 Protein of unknown function DUF89 K09116 - - 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
MMD2_k127_5924179_3 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000002658 225.0
MMD2_k127_5924179_4 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000005988 235.0
MMD2_k127_5924179_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000001642 195.0
MMD2_k127_5924179_6 Belongs to the SUA5 family K07566 - 2.7.7.87 0.00000000000000000000000000000000000000001348 161.0
MMD2_k127_5924179_7 RNA-binding protein - - - 0.00000000000000000000001998 102.0
MMD2_k127_5951433_0 Protein of unknown function (DUF1318) - - - 0.00000000000000000000000000000000000000000007054 167.0
MMD2_k127_5951433_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000001172 148.0
MMD2_k127_5951433_2 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.00000000000000000005936 93.0
MMD2_k127_5974156_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 582.0
MMD2_k127_5974156_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 461.0
MMD2_k127_5974156_10 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000002271 153.0
MMD2_k127_5974156_11 FabA-like domain - - - 0.00000000000000000000000000000001153 131.0
MMD2_k127_5974156_13 Protein of unknown function (DUF507) - - - 0.000000000000000000000000000006833 120.0
MMD2_k127_5974156_14 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000006053 113.0
MMD2_k127_5974156_15 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000002101 104.0
MMD2_k127_5974156_16 Protein of unknown function (DUF507) - - - 0.00000000000000000000005866 102.0
MMD2_k127_5974156_17 Putative methyltransferase - - - 0.00000000000000000004279 104.0
MMD2_k127_5974156_18 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.00000000006104 66.0
MMD2_k127_5974156_19 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.00001098 48.0
MMD2_k127_5974156_2 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 460.0
MMD2_k127_5974156_3 Beta-ketoacyl synthase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 385.0
MMD2_k127_5974156_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007186 374.0
MMD2_k127_5974156_5 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002123 257.0
MMD2_k127_5974156_6 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000000000000000000000000000000000000000000000000000003791 211.0
MMD2_k127_5974156_7 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000002161 190.0
MMD2_k127_5974156_8 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000004188 176.0
MMD2_k127_5974156_9 SMART HNH nuclease K07451 - - 0.000000000000000000000000000000000000000002315 157.0
MMD2_k127_5998979_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.095e-196 621.0
MMD2_k127_5998979_1 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 411.0
MMD2_k127_5998979_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005578 359.0
MMD2_k127_5998979_3 Conserved region in glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 335.0
MMD2_k127_5998979_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000009183 211.0
MMD2_k127_5998979_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000007973 107.0
MMD2_k127_6003759_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000002714 175.0
MMD2_k127_6003759_1 - - - - 0.0000000000000000007244 91.0
MMD2_k127_6003759_2 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.000005367 48.0
MMD2_k127_602019_0 ATPase BadF BadG BcrA BcrD type - - - 1.44e-212 678.0
MMD2_k127_602019_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 298.0
MMD2_k127_602019_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000001467 191.0
MMD2_k127_6051002_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 366.0
MMD2_k127_6051002_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 364.0
MMD2_k127_6064251_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 1.31e-196 648.0
MMD2_k127_6064251_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 441.0
MMD2_k127_6064251_2 adenylate kinase activity K00939,K01939 - 2.7.4.3,6.3.4.4 0.00000000000000000000000000000000000000000000007074 176.0
MMD2_k127_6067507_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 2.083e-318 981.0
MMD2_k127_6067507_1 cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000001318 241.0
MMD2_k127_6092844_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000001235 186.0
MMD2_k127_6092844_1 radical SAM K06871 - - 0.0000000000000000000000000000000000000075 158.0
MMD2_k127_6154564_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 8.779e-239 754.0
MMD2_k127_6154564_1 GAF domain - - - 1.131e-206 693.0
MMD2_k127_6154564_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001898 269.0
MMD2_k127_6154564_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000001982 227.0
MMD2_k127_6154564_4 PFAM ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000104 207.0
MMD2_k127_6154564_5 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000006757 163.0
MMD2_k127_6224870_0 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003244 267.0
MMD2_k127_6224870_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000000000000000000000000000000000000000248 234.0
MMD2_k127_6224870_2 O-methyltransferase family 3 - - - 0.000000000000000000000000000000000000000000000000000000000001504 216.0
MMD2_k127_6224870_3 Universal stress protein family K07090 - - 0.00000000003666 63.0
MMD2_k127_6240211_0 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 525.0
MMD2_k127_6240211_1 Sigma-54 interaction domain K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 442.0
MMD2_k127_6240211_2 Universal stress protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000008039 246.0
MMD2_k127_6240211_3 FtsZ-dependent cytokinesis - - - 0.00000000000000000000000000000000000000000000000000000000000006683 218.0
MMD2_k127_6240211_4 histidine kinase HAMP region domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000001518 210.0
MMD2_k127_6240211_5 membrane K00389 - - 0.00000000000000000000000000000000000000002642 157.0
MMD2_k127_6240211_6 EamA-like transporter family - - - 0.00000000000000000000000000000000008208 137.0
MMD2_k127_6240211_7 - - - - 0.0000000000000000003501 89.0
MMD2_k127_6264277_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 427.0
MMD2_k127_6264277_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 374.0
MMD2_k127_6264277_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 346.0
MMD2_k127_6264277_3 Thioredoxin - - - 0.0000000000000000000000000000000000003444 153.0
MMD2_k127_6266794_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.58e-276 863.0
MMD2_k127_6266794_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 9.104e-195 614.0
MMD2_k127_6266794_10 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000003002 190.0
MMD2_k127_6266794_11 phenylalanine-tRNA ligase activity K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000001996 181.0
MMD2_k127_6266794_12 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000004798 141.0
MMD2_k127_6266794_13 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000001704 125.0
MMD2_k127_6266794_14 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000005627 91.0
MMD2_k127_6266794_15 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000008412 79.0
MMD2_k127_6266794_16 - - - - 0.000007971 50.0
MMD2_k127_6266794_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 470.0
MMD2_k127_6266794_3 B3/4 domain K01890 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 402.0
MMD2_k127_6266794_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 378.0
MMD2_k127_6266794_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 319.0
MMD2_k127_6266794_6 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007569 270.0
MMD2_k127_6266794_7 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000104 221.0
MMD2_k127_6266794_8 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000001155 201.0
MMD2_k127_6266794_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000232 203.0
MMD2_k127_647692_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002381 269.0
MMD2_k127_647692_1 PFAM Glycosyl transferases group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000131 225.0
MMD2_k127_65385_0 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 408.0
MMD2_k127_65385_1 PFAM Cys Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 356.0
MMD2_k127_65385_2 membrane K09133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 298.0
MMD2_k127_65385_3 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000004263 233.0
MMD2_k127_65385_4 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000000009755 211.0
MMD2_k127_65385_5 4Fe-4S binding domain K00176 - 1.2.7.3 0.0000000000000000004564 90.0
MMD2_k127_65385_6 Metal-dependent phosphohydrolase K06950 - - 0.0000000000000000371 83.0
MMD2_k127_664791_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 447.0
MMD2_k127_664791_1 histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002891 361.0
MMD2_k127_664791_2 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.0000000000000000000000000000000000000000000000000000000000002282 218.0
MMD2_k127_664791_3 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000000000000000381 209.0
MMD2_k127_664791_4 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000006066 188.0
MMD2_k127_664791_5 cheY-homologous receiver domain - - - 0.000000000000000003509 87.0
MMD2_k127_6771_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 7.11e-297 928.0
MMD2_k127_6771_1 cytochrome C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 397.0
MMD2_k127_6771_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001053 272.0
MMD2_k127_6771_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001306 285.0
MMD2_k127_6771_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000001296 209.0
MMD2_k127_6771_5 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000164 126.0
MMD2_k127_6771_6 chlorophyll binding K03286,K07275 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000003093 130.0
MMD2_k127_6771_7 - - - - 0.00000000000000000000000000001626 136.0
MMD2_k127_6771_8 Cadherin repeats. - - - 0.0000000000000000000002063 113.0
MMD2_k127_67824_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 394.0
MMD2_k127_67824_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 326.0
MMD2_k127_67824_2 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000009795 59.0
MMD2_k127_76784_0 Nitroreductase - - - 4.78e-196 625.0
MMD2_k127_76784_1 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008693 274.0
MMD2_k127_76784_2 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.000000000000000000000000000000000003432 143.0
MMD2_k127_76784_3 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000008123 128.0
MMD2_k127_76784_4 Carboxymuconolactone decarboxylase family - - - 0.000000002996 64.0
MMD2_k127_790450_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.254e-207 657.0
MMD2_k127_790450_1 AAA ATPase K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004204 458.0
MMD2_k127_790450_2 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 327.0
MMD2_k127_790450_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 325.0
MMD2_k127_790450_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000003027 124.0
MMD2_k127_790450_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000001475 90.0
MMD2_k127_790450_6 carbon dioxide binding K04653 - - 0.0000000000007462 70.0
MMD2_k127_798772_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.252e-200 632.0
MMD2_k127_798772_1 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000003767 101.0
MMD2_k127_826230_0 helix_turn_helix, Lux Regulon K02282 - - 0.000000000000000000000000000000000000000000000000000000000000000000001953 242.0
MMD2_k127_826230_1 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000004915 205.0
MMD2_k127_826230_2 Histidine kinase K07675 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000003689 212.0
MMD2_k127_83208_0 Transport of potassium into the cell K03549 - - 9.273e-244 766.0
MMD2_k127_83208_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 372.0
MMD2_k127_83208_2 Protein of unknown function (DUF2400) - - - 0.00000000000000000000002532 103.0
MMD2_k127_838756_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006395 440.0
MMD2_k127_838756_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000005799 195.0
MMD2_k127_838756_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000114 143.0
MMD2_k127_838756_3 cyclic nucleotide binding K10914 - - 0.0000000000000000000002075 102.0
MMD2_k127_838756_4 cyclic nucleotide binding K10914 - - 0.0000000000000000000002835 100.0
MMD2_k127_842552_0 Chromate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 434.0
MMD2_k127_842552_1 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000002803 210.0
MMD2_k127_842552_2 Universal stress protein family K07090 - - 0.0000000000000000000000000000000000000000000000000104 190.0
MMD2_k127_842552_3 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.00000000004919 64.0
MMD2_k127_857172_0 PFAM Cysteine-rich domain K08264 - 1.8.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 333.0
MMD2_k127_857172_1 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000006108 164.0
MMD2_k127_857172_2 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000001755 103.0
MMD2_k127_857172_3 4Fe-4S dicluster domain - - - 0.00000008021 59.0
MMD2_k127_858095_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 5.99e-267 848.0
MMD2_k127_858095_1 Protein of unknown function, DUF255 K06888 - - 4.691e-242 764.0
MMD2_k127_858095_2 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 383.0
MMD2_k127_858095_3 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005035 284.0
MMD2_k127_858095_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000002173 190.0
MMD2_k127_858095_5 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.0000000000000000000000000000008387 129.0
MMD2_k127_866848_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005876 640.0
MMD2_k127_866848_1 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 336.0
MMD2_k127_866848_2 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 308.0
MMD2_k127_866848_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009889 258.0
MMD2_k127_866848_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000001324 252.0
MMD2_k127_866848_5 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K13531 - 2.1.1.63 0.0000000000000000000000000000000004983 136.0
MMD2_k127_866848_6 NAD(P)-binding Rossmann-like domain K00316 - 1.5.99.6 0.000000000000000000000000000004234 124.0
MMD2_k127_866848_7 - - - - 0.00000000000000000000001104 101.0
MMD2_k127_866848_8 - - - - 0.0000000000000000000005676 98.0
MMD2_k127_868968_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 467.0
MMD2_k127_868968_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002191 382.0
MMD2_k127_868968_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 368.0
MMD2_k127_868968_3 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 300.0
MMD2_k127_868968_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000004447 158.0
MMD2_k127_89902_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 1.289e-266 830.0
MMD2_k127_89902_1 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000000004626 239.0
MMD2_k127_89902_2 PHP-associated K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000004151 233.0
MMD2_k127_89902_3 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000000001253 191.0
MMD2_k127_89902_4 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000003835 184.0
MMD2_k127_89902_5 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.0000000000000000000000000000000000002838 141.0
MMD2_k127_89902_6 DRTGG domain - - - 0.0000000000000000000000000000002342 126.0
MMD2_k127_89902_7 Domain in cystathionine beta-synthase and other proteins. K06041 - 5.3.1.13 0.0000000000000000001575 89.0
MMD2_k127_901924_0 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 1.648e-232 729.0
MMD2_k127_901924_1 Phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 339.0
MMD2_k127_913525_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.758e-292 912.0
MMD2_k127_913525_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007958 460.0
MMD2_k127_913525_10 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000003422 224.0
MMD2_k127_913525_11 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000006059 220.0
MMD2_k127_913525_12 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000002283 213.0
MMD2_k127_913525_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000003986 198.0
MMD2_k127_913525_14 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000002319 205.0
MMD2_k127_913525_15 DoxX K15977 - - 0.0000000000000000000000000000000000001366 146.0
MMD2_k127_913525_16 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000007544 129.0
MMD2_k127_913525_17 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000001194 80.0
MMD2_k127_913525_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 434.0
MMD2_k127_913525_3 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 417.0
MMD2_k127_913525_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 408.0
MMD2_k127_913525_5 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 387.0
MMD2_k127_913525_6 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 379.0
MMD2_k127_913525_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 358.0
MMD2_k127_913525_8 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 324.0
MMD2_k127_913525_9 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000001957 273.0
MMD2_k127_918801_0 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
MMD2_k127_918801_1 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001432 283.0
MMD2_k127_918801_2 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000000000000007182 114.0
MMD2_k127_918801_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.00000000000000000000000002965 117.0
MMD2_k127_918801_4 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.000000000000001313 83.0
MMD2_k127_924612_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 7.026e-266 842.0
MMD2_k127_924612_1 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006569 611.0
MMD2_k127_924612_10 FixH - - - 0.000000000000000000000001013 108.0
MMD2_k127_924612_11 Glycosyl transferase, family 2 - - - 0.00000000000000000000004682 111.0
MMD2_k127_924612_12 Rhodanese Homology Domain - - - 0.000000000000000000001417 95.0
MMD2_k127_924612_13 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000002554 91.0
MMD2_k127_924612_14 TIGRFAM cytochrome oxidase maturation protein, cbb3-type - - - 0.000000000000004477 78.0
MMD2_k127_924612_15 PFAM ABC transporter K06158 - - 0.0000000000006492 72.0
MMD2_k127_924612_2 HI0933-like protein K07007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 428.0
MMD2_k127_924612_3 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 369.0
MMD2_k127_924612_4 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 297.0
MMD2_k127_924612_5 nucleoside-triphosphate diphosphatase activity K06287 - - 0.0000000000000000000000000000000000000000000000001973 184.0
MMD2_k127_924612_6 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000193 179.0
MMD2_k127_924612_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000001771 167.0
MMD2_k127_924612_8 conserved protein UCP033924 - - - 0.00000000000000000000000000000000000000003004 157.0
MMD2_k127_924612_9 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000274 159.0
MMD2_k127_948581_0 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
MMD2_k127_948581_2 - - - - 0.000003951 54.0
MMD2_k127_951440_0 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 1.546e-252 800.0
MMD2_k127_951440_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 610.0
MMD2_k127_951440_2 TIGRFAM riboflavin biosynthesis protein RibF K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003766 290.0
MMD2_k127_951440_3 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006097 295.0
MMD2_k127_951440_4 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000005215 226.0
MMD2_k127_951440_5 Transcriptional regulator, MerR family - - - 0.00000000000000000000000000000000007608 138.0
MMD2_k127_951440_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000213 94.0
MMD2_k127_951440_7 Histidine kinase K02660,K11525 - - 0.00000001116 68.0
MMD2_k127_951440_8 Belongs to the Fur family K03711 - - 0.00001774 47.0
MMD2_k127_951440_9 - - - - 0.00007884 45.0
MMD2_k127_977751_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 1.078e-237 743.0
MMD2_k127_977751_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 467.0
MMD2_k127_977751_2 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006582 394.0
MMD2_k127_977751_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 382.0
MMD2_k127_977751_4 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000001535 179.0
MMD2_k127_977751_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K05922,K06281 - 1.12.2.1,1.12.5.1,1.12.99.6 0.0000000000000000000000000000000009409 130.0
MMD2_k127_977751_6 Hydrogenase expression formation protein K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000005004 89.0
MMD2_k127_988823_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 1.876e-204 642.0
MMD2_k127_988823_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 371.0
MMD2_k127_988823_10 Belongs to the UPF0296 family K09777 - - 0.00001275 47.0
MMD2_k127_988823_2 Metallopeptidase family M24 K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004756 285.0
MMD2_k127_988823_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000002635 239.0
MMD2_k127_988823_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000003829 208.0
MMD2_k127_988823_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000154 176.0
MMD2_k127_988823_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000001597 171.0
MMD2_k127_988823_7 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000000202 124.0
MMD2_k127_988823_8 Roadblock/LC7 domain - - - 0.00000000000000000000792 96.0
MMD2_k127_988823_9 Tetratricopeptide repeat - - - 0.00000000000000000001916 104.0